Homeodomain Sequences
SD Subsets, V Plots - pnas.org
... En-1, Evx-1, GBX2, Gsh-1, Gtx, HD1, HNF-6, HOXB6, ISL1, KIAA0395, Lbx1, LH2,
Lim-1, LMX1, MEIS1, Mix.1, MOX1, MSX1.7, Nkx-2.1, OCT-1, Oct-3/4, PBX1, Pem, PROX1 ...
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20, 847–854 (1998). - Full text - MIT Libraries
N Methods, J Microsc - Proc. Natl Acad. Sci. USA, 1994 - nature.com
... 1j–o). This indicates that mMeis1/2 promotes nuclear localization of Pbx1 and argues
for ... Limbs in c were double-stained for alcian blue and msx1 . ...
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Analysis of HOX Homeodomain Proteins and Gene Transcripts in the Epidermis
LG Koemueves, C Largman - now.humanapress.com
... 2. MSX1: rabbit anti-peptide. ... Cruz Biotechnology (scbt@scbt.com); antibodies marked
with an “x” have been successfully used with epidermal tissue PBX1 (P-20 ...
Web Search - journals.humanapress.com - biomed.humanapress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Gtx, an oligodendrocyte-specific homeodomain protein, has repressor activity - Full text - MIT Libraries
R Awatramani, J Beesley, H Yang, H Jiang, F Cambi, … - Journal of Neuroscience Research, 2000 - doi.wiley.com
... domain, Gtx re- pressed transcription with a magnitude similar to that of other
known repressors, including SMRT (Nagy et al., 1997) and Msx1 (Catron et al ...
Cited by 7 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The Protein Kinase C Pathway Acts Through Multiple Transcription Factors to Repress Gonadotropin- …
Q Tang, M Mazur, PL Mellon - mend.endojournals.org
... Phosphorylation of the PBC-B domain of Pbx1 by PKA blocks the nuclear export, leading
to its nuclear accumulation (27). Since ... homeodomain protein Dlx2 or Msx1. ...
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Deregulated homeobox gene expression in cancer: cause or consequence? - Full text - MIT Libraries
C Abate-Shen - Nature Reviews Cancer, 2002 - nature.com
... Nature 360, 477-481 (1992). Shows that overpression of Msx1 (formerly Hox-7.1) in
cell culture blocks differentiation and promotes a transformed phenotype. ...
Cited by 38 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Fibroblast growth factor receptors(FGFRs) and their roles in limb development - Full text - MIT Libraries
X Xu, M Weinstein, C Li, CX Deng - Cell and Tissue Research, 1999 - springerlink.com
... Page 6. shown that FGF signals regulate Msx1 expression in the progress
zone of the limb bud (Wang and Sassoon 1995). We found that ...
Cited by 69 - Web Search - ncbi.nlm.nih.gov

Homeobox genes in normal and malignant cells - Full text - MIT Libraries
C Cillo, M Cantile, A Faiella, E Boncinelli - Journal of Cellular Physiology, 2001 - doi.wiley.com
... cells, where the signalling protein BMP4 induces apoptosis via Msx1 and Msx2 and ...
Besides homeobox genes, chime- rical HD protein E2A-PBX1 induces apoptosis and ...
Cited by 30 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

An Otx-related homeodomain protein binds an LHss promoter element important for activation during … - Full text - MIT Libraries
SB Rosenberg, PL Mellon - Mol Endocrinol, 2002 - mend.endojournals.org
... appears to be limited to Ptx and Otx HD family members as it fails to interact with
other HD proteins such as Oct-1, Pbx1/2/3, PREP-1, Msx1, and Dlx2 (Fig. ...
Cited by 15 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

Homeodomain revisited: a lesson from disease-causing mutations - Full text - MIT Libraries
YI Chi - Human Genetics, 2005 - springerlink.com
... Hypodontia MSX1 142983 Homeodomain (166–225) R196P PS/DB ... E17 PO4 on G PO4 on T
PBX1 Mouse Homeodomain 1PUF N3 on A O2 on T O4¢ on T O4¢ on A ...
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Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif - Full text - MIT Libraries
ML Phelan, I Rambaldi, MS Featherstone - Mol. Cell. Biol, 1995 - mcb.asm.org
... The naturally occurring fusion of the transcriptional activation domain of E2A with
PBX1 creates an oncoprotein implicated in human pre-B-cell leukemias (MP ...
Cited by 111 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... Transcription factors are frequent targets in these lesions, and rearrangements
can result in the generation of fusion proteins, as in E2A-PBX1 associated with ...
Cited by 32 - Web Search - stemcells.alphamedpress.org - dx.doi.org - ncbi.nlm.nih.gov

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity - Full text - MIT Libraries
B Kammandel, K Chowdhury, A Stoykova, S Aparicio, … - Dev. Biol, 1999 - fbmc.fcen.uba.ar
Page 1. Distinct cis-Essential Modules Direct the Time– Space Pattern of
the Pax6 Gene Activity Birgitta Kammandel, Kamal Chowdhury ...
Cited by 66 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TALE Homeodomain Proteins Regulate Gonadotropin-releasing Hormone Gene Expression Independently and … - Full text - MIT Libraries
N Rave-Harel, ML Givens, SB Nelson, HA Duong, D … - J Biol Chem, 2004 - jbc.org
... Finally, Pbx1 is expressed in GnRH neurons in embryonic, as well as mature mice,
suggesting ... proteins Oct-1 (7), SCIP/Oct-6 (8), Brn2 (9), Dlx2 and Msx1 (MLG, NR ...
Cited by 3 - Web Search - jbc.org - ncbi.nlm.nih.gov

Transcriptional Control of the Cell Cycle in Mammary Gland Development and Tumorigenesis
RD Coletta, P Jedlicka, A Gutierrez-Hartmann, HL … - Journal of Mammary Gland Biology and Neoplasia, 2004 - springerlink.com
... For example, Msx1 overexpression in myogenic precursors blocks their differentiation
(53), and Msx genes have been shown to inhibit chondrogenic and osteogenic ...
Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD 13 … - Full text - MIT Libraries
P Debeer, C Bacchelli, PJ Scambler, L De Smet, JP … - Journal of Medical Genetics, 2002 - dx.doi.org
... AH, Chang CP, Cleary ML, Wolberger C. Structure of a HoxB1-Pbx1 heterodimer bound ...
A human MSX1 homeodomain missense mutation causes selective tooth agenesis. ...
Cited by 9 - Web Search - jmg.bmjjournals.com - jmg.bmjjournals.com - ncbi.nlm.nih.gov - all 5 versions »

Sonic hedgehog signaling at gastrula stages specifies ventral telencephalic cells in the chick … - Full text - MIT Libraries
L Gunhaga, TM Jessell, T Edlund - Development, 2000 - dev.biologists.org
... pan anti-Dlx rabbit antibody (Panganiban et al., 1995), Nkx2.2 with mAb Nkx2.2
(Ericson et al., 1997), Pax7 with mAb Pax7 (Ericson et al., 1996), Msx1 with mAb ...
Cited by 23 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... SF1 B SF1 steroidogenic factor 1 Core should be CAAGG not AAGG PBX1 02 Homeo
domain factor Pbx-1 Core should be CAATC not CAAT MAX ...
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Extracellular signals, cell interactions and transcription factors involved in the induction of the … - Full text - MIT Libraries
MJ AYBAR, A GLAVIC, R MAYOR - Biol Res, 2002 - scielo.cl
... genes in the neural fold region may be controlled by the Meis1/Pbx1 genes, as ... The
dynamic expression patterns of Msx1 and AP-2 genes suggest they could have ...
Cited by 12 - Cached - Web Search - scielo.cl - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular evolution of the homeodomain family of transcription factors - Full text - MIT Libraries
S Banerjee-Basu, AD Baxevanis - Nucleic Acids Research, 2001 - nar.oupjournals.org
... 2). Furthermore, MSX1 is closely linked to two NK class members (HMX1 and BAPX1 ...
Cleary,ML and Wolberger,C. (1999) Structure of a HoxB1-Pbx1 heterodimer bound to ...
Cited by 25 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Comparative genomics provides evidence for an ancient genome duplication event in sh
JS Taylor, Y Van de Peer, I Braasch, A Meyer - Phil. Trans. R. Soc. Lond. B, 2001 - journals.royalsoc.ac.uk
Page 1. Comparative genomics provides evidence for an ancient genome duplication
event in sh John S. Taylor, Yves Van de Peer, Ingo Braasch and Axel Meyer * ...
Cited by 102 - Web Search - evolutionsbiologie.uni-konstanz.de - mit.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Septo-Optic Dysplasia and Related Malformations
MT Dattani - Hypothalamic-pituitary development: genetic and clinical …, 2001 - content.karger.com
... PAX3 (Waardenberg syndrome type I), PAX6 (anir- idia), MSX1 (selective tooth ... Recent
structural studies of the Pbx1 class homeodomains [78, 79] highlight the ...
Cited by 2 - Web Search - content.karger.com

HESX1 and Septo-Optic Dysplasia
MT Dattani, IC Robinson - Reviews in Endocrine & Metabolic Disorders, 2002 - springerlink.com
... coloboma syndrome), PAX3 (Waardenberg syndrome type I), PAX6 (aniridia), MSX1
(selective tooth ... Recent structural studies of the Pbx1 class homeodomains [82,83 ...
Cited by 3 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Conserved and muscle group-specific gene expression patterns shape postnatal development of the … - Full text - MIT Libraries
G Cheng, AP Merriam, B Gong, P Leahy, S Khanna, JD … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... responsive to retinoic acid (eg, Pax2, 25%; Msx1, 23%; Hoxa3, 21%; Znf42, 19%; Pitx2,
15%; Tfap2a, 10%; Pbx1, 8%; Hnf3b, 6%) also were detected at moderate ...
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Developmental functions of the Distal-less/Dlx homeobox genes - Full text - MIT Libraries
G Panganiban, JL Rubenstein - Development, 2002 - dev.biologists.org
... For example, Msx1 is required to maintain Dlx2 (but not Dlx1) expression
in the branchial arch mesenchyme (Bei and Maas, 1998 ). ...
Cited by 51 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Construction and analysis of a subtracted library and microarray of cDNAs expressed specifically in … - Full text - MIT Libraries
M Afrakhte, TM Schultheiss - Developmental Dynamics, 2004 - doi.wiley.com
... sialyltransferase (Fig. 3D), Meis1 (Moskow et al., 1995; Fig. 3B), Msx1 (Hill
et al., 1989; Fig. 3E), Bambi (Onichtchouk et al., 1999; Fig. 3L ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Meningioma Expression Analysis
G Wrobel - dkfz-heidelberg.de
Page 1. Meningioma Expression Analysis Gunnar Wrobel February 26, 2004 Page
2. Contents 1 Preprocessing 3 1.1 Introduction . . . . . ...
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HOXB 13 homeodomain protein is cytoplasmic throughout fetal skin development - Full text - MIT Libraries
LG Koemueves, XK Ma, E Stelnicki, S Rozenfeld, Y … - Developmental Dynamics, 2003 - doi.wiley.com
... In addition, we have reported previ- ously that the non-HOX homeodo- main proteins
MSX1 and MSX2 also exhibit predominant cytoplasmic ex- pression in embryonic ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

HOXB 4 homeodomain protein is expressed in developing epidermis and skin disorders and modulates … - Full text - MIT Libraries
LG Koemueves, E Michael, JM Arbeit, XK Ma, A Kwong … - Developmental Dynamics, 2002 - doi.wiley.com
... The PBX1 gene was first identified as an oncogenic fusion between the PBX ... the HOXB6
(Kömüves et al., 2001) and the non-HOX homeodomain proteins MSX1 and MSX2 ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov

[CITATION] The HOX homeodomain proteins block CBP histone acetyltransferase activity - Full text - MIT Libraries
WF Shen, K Krishnan, HJ Lawrence, C Largman - Mol. Cell. Biol, 2001
Signal Transduction Virtual Journal Home > Literature > Virtual Journal > Shen
et al., pp. 7509-7522. Mol. Cell. Biol. 21 (21): 7509-7522. ...
Cited by 21 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - dx.doi.org - all 6 versions »

Evidence for a direct functional antagonism of the selector genes proboscipedia and eyeless in … - Full text - MIT Libraries
C Benassayag, S Plaza, P Callaerts, J Clements, Y … - Development, 2003 - dev.biologists.org
... in quail (Plaza et al., 1997 ), and between Pax3 and Msx1 for muscle ... of a novel
nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA. ...
Cited by 4 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Luciferase Reporters: Less is More
A Paguio, B Almond, F Fan, P Stecha, D Garvin, M … - promega.com
... v-Myb Pbx1/Meis1 RFX1 TATA Brn3 CHOP CCAAT CCAAT CCAAT VIS1 CDE/CHR Smad4 Se-CtRNA
ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA HNF1 SRF SRF GATA MSX1/MSX-2 ...
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Developmental functions of the Distal-less/Dlx homeobox genes - Full text - MIT Libraries
D DISTAL-LESS - Development, 2002 - ntp.neuroscience.wisc.edu
... For example, Msx1 is required to maintain Dlx2 (but not Dlx1) expression
in the branchial arch mesenchyme (Bei and Maas, 1998). ...
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Use of Heterologous cDNA Array Screening to Analyze Bovine Oocyte Transcriptome and its Evolution …
R DALBIES-TRAN, P MERMILLOD - biolreprod.org
Page 1. Use of Heterologous cDNA Array Screening to Analyze Bovine Oocyte
Transcriptome and its Evolution During In Vitro Maturation ...
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ES cell neural differentiation reveals a substantial number of novel ESTs
G Bain, FC Mansergh, MA Wride, JE Hance, A Isogawa … - Functional & Integrative Genomics, 2000 - springerlink.com
Page 1. Abstract We have used a method for synchronously dif- ferentiating murine
embryonic stem (ES) cells into func- tional neurons and glia in culture. ...
Cited by 4 - Web Search - 136.159.173.207 - camit.org - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

MCN - Full text - MIT Libraries
YA Zhang, A Okada, CH Lew, SK McConnell - Molecular and Cellular Neuroscience, 2002 - stanford.edu
Page 1. Regulated Nuclear Trafficking of the Homeodomain Protein Otx1 in
Cortical Neurons Y. Alex Zhang, 1,2 Ami Okada, 1 Chuen Hong ...
Cited by 5 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

pGL3 Luciferase Reporter Vectors
I Description, IIIP Components, IVC Methods, I … - promega.com
... v-Myb Pbx1/Meis1 RFX1 TATA Brn3 CHOP CCAAT CCAAT CCAAT VIS1 CDE/CHR Smad4 Se-CtRNA
ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA HNF1 SRF SRF GATA MSX1/MSX-2 ...
Web Search - genomics.sbg.ac.at - sci.sdsu.edu - shpromega.cn - all 8 versions »

Molecular basis for the inhibition of Drosophila eye development by Antennapedia - Full text - MIT Libraries
S Plaza, F Prince, J Jaeger, U Kloter, S Flister, … - The EMBO Journal, 2001 - embojournal.npgjournals.com
... of a novel nonhomeodomain protein that inhibits the binding of PBX1–HOX complexes ...
AJ, Ding,J., Hu,G., Shen,MM and Abate-Shen,C. (1999) Msx1 antagonizes the ...
Cited by 15 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

Specification and Morphogenesis of the Zebrafish Larval Head Skeleton - Full text - MIT Libraries
C Kimmel, CT Miller, CB Moens - Developmental Biology, 2001 - neuro.uoregon.edu
... Several differences exist however; for example Et-1 mutant mice have normal Msx1
expression (Thomas et al., 1998) whereas an msx gene in fish seems to more ...
Cited by 26 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Snail precedes Slug in the genetic cascade required for the specification and migration of the … - Full text - MIT Libraries
MJ Aybar, MA Nieto, R Mayor - Development, 2003 - dev.biologists.org
... include BMP4 and the genes downstream of it, such as Msx1 and the ... to be expressed
in the prospective neural crest of Xenopus embryos (Meis1, Pbx1, several Zic ...
Cited by 21 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov

FGFs and Wnts in pancreatic growth and
S Papadopoulou - diva-portal.org
... mesenchyme (Esni et al, 2001) and in mice lacking the homeobox gene Pbx1, albeit
less severe (Kim et al, 2002). ... mesenchyme. The Pbx1 mutants ...
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The pathophysiology of HOX genes and their role in cancer - Full text - MIT Libraries
DG Grier, A Thompson, A Kwasniewska, GJ McGonigle, … - J Pathol, 2005 - doi.wiley.com
Page 1. Journal of Pathology J Pathol 2005; 205: 154–171 Published online in Wiley
InterScience (www.interscience.wiley.com). DOI: 10.1002/path.1710 ...
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Snail precedes Slug in the genetic cascade required for the specification and migration of the … - Full text - MIT Libraries
S Xenopus - Development - codon.ciencias.uchile.cl
Page 1. INTRODUCTION The neural crest comprises a unique set of cells,
which segregates from the dorsal part of the neural tube. ...
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Developmental gene expression profiling of mammalian, fetal orofacial tissue
P Mukhopadhyay, RM Greene, W Zacharias, MC … - Birth Defects Research Part A Clinical and Molecular …, 2004 - doi.wiley.com
Page 1. Original Articles Developmental Gene Expression Profiling of Mammalian,
Fetal Orofacial Tissue Partha Mukhopadhyay, 1 Robert ...
Cited by 3 - Web Search - louisville.edu - louisville.edu - ncbi.nlm.nih.gov - Get it from MIT Libraries

Early steps in the evolution of multicellularity: deep structural and functional homologies among … - Full text - MIT Libraries
CC Coutinho, RN Fonseca, JJC Mansure, R Borojevic - Mechanisms of Development, 2003 - faculty.virginia.edu
... A43561; Msh-like 3 M. musculus (Chordata), NP_034966, Msx1 H. sapiens (Chordata),
AAL17870; Msx-2 M. musculus, (Chordata), Q03358; Nk-1 D. melanogaster ...
Cited by 4 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

1.1 Mechanismen der Steuerung der Embryonalentwicklung
B Christ, B Brand-Saberi - springeronline.com
Page 1. 1.1 Mechanismen der Steuerung der Embryonalentwicklung Bodo Christ
und Beate Brand-Saberi Wer weiter nichts als die Kreaturen ...
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Upper beak truncation in chicken embryos with the cleft primary palate mutation is due to an … - Full text - MIT Libraries
ME MacDonald, UK Abbott, JM Richman - DEVELOPMENTAL DYNAMICS, 2004 - doi.wiley.com
Page 1. PATTERNS & PHENOTYPES Upper Beak Truncation in Chicken Embryos With
the cleft primary palate Mutation Is Due to an Epithelial ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

I. I ntroduction
IV References - promega.com
... v-Myb Pbx1/Meis1 RFX1 TATA Brn3 CHOP CCAAT CCAAT CCAAT VIS1 CDE/CHR Smad4 Se-CtRNA
ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA ST/TA HNF1 SRF SRF GATA MSX1/MSX-2 ...
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[BOOK] Role of epidermal and fibroblast growth factors in pancreatic development
MA Pulkkinen, B Helsinki - 2003 - ethesis.helsinki.fi
... the homeodomain family (Pdx1, Hb9, Pbx1, HNF6, Pax4, Pax6, Nkx2.2, Nkx6.1, Isl1,
HNF1a, ... At e14.5 PBX1 is expressed in the ductal epithelial cells, ...
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The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix … - Full text - MIT Libraries
JA Bruun, EIS Thomassen, K Kristiansen, G Tylden, … - Nucleic Acids Research, 2005 - nar.oxfordjournals.org
... R57 and R58 in helix 3 of the homeodomain We have previously shown that Pax6 PD
as well as other homeodomain proteins, such as Rax, Chx10, HoxB1, Pbx1 and Lhx2 ...
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