Expression of stem cell markers and transcription factors during the remodeling of the rat pancreas … - Full text - MIT Libraries
K Peters, R Panienka, J Li, G Kloeppel, R Wang - Virchows Archiv, 2005 - springerlink.com
... Ngn3 and Pax4 [21]. These transcription factors, to which we limited our studies,
include the pancreatic and duodenal homeobox gene 1 (Pdx1), Pbx1 and Nkx2.2 ...
Web Search - ncbi.nlm.nih.gov

Regulatory Sequence Analysis of Coclustering Genes
A TFBS - ahavj.ahajournals.org
... PBX1, 12/52=23, 9/29=31, 3/11=27, 1/6=17, 3/16=19, 2/3=67, 3/4=75, 0/9=0, 0/1=0,
0/1=0. ... PAX4, 22/52=42, 11/29=38, 2/11=18, 4/6=67, 8/16=50, 1/3=33, 1/4=25, 3/9=67 ...
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Heterodimeric Pbx-Prep 1 Homeodomain Protein Binding to the Glucagon Gene Restricting Transcription … - Full text - MIT Libraries
S Herzig, L Fuezesi, W Knepel - J Biol Chem, 2000 - jbc.org
... LIM-homeodomain protein lsl-1, and the paired homeodomain proteins Pax4 and Pax6
(6 ... gene are molecularly identified as heterodimers consisting of Pbx1/2, which ...
Cited by 12 - Web Search - intl.jbc.org - jbc.org - ncbi.nlm.nih.gov

Advances in islet cell biology: from stem cell differentiation to clinical transplantation: …
F KANDEEL, CV SMITH, I TODOROV, Y MULLEN - Pancreas, 2003 - pancreasjournal.com
... Pbx1 is a member of the TALE class of homeodomain transcription factors that regulate
the activity of ... Ngn3 turns on several genes, including PAX4 and NKX2.2. ...
Cited by 2 - Web Search - pancreasjournal.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Pancreatic transcription factors: implications for diabetes therapy. - Full text - MIT Libraries
MD Walker - Isr Med Assoc J, 2004 - ima.org.il
... that some of the effects require heterodimerization with the homeodomain protein
Pbx1 [10 ... reduced islet cell number [7]. Several other factors (Pax4, Pax6, Nkx2 ...
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[BOOK] Role of epidermal and fibroblast growth factors in pancreatic development
MA Pulkkinen, B Helsinki - 2003 - ethesis.helsinki.fi
... development. These belong to the homeodomain family (Pdx1, Hb9, Pbx1, HNF6,
Pax4, Pax6, Nkx2.2, Nkx6.1, Isl1, HNF1a, HNF4a, Brn4 ...
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Progenitor cells in the adult pancreas
AM Holland, LJ Gonez, LC Harrison - Diabetes/Metabolism Research and Reviews, 2004 - doi.wiley.com
... Ngn3 Loss of endocrine precursors, islet cells and expression of Isl1, Pax4/6 and
NeuroD. [43] Pbx1 Multiple developmental abnormalities including hypoplasia ...
Cited by 7 - Web Search - pi.be - ncbi.nlm.nih.gov - Get it from MIT Libraries

Development and diseases of the pancreas. - Full text - MIT Libraries
KA Johansson, A Grapin-Botton - Clinical Genetics, 2002 - ingentaconnect.com
... Transactivates the last two (48) PAX4 Increase of a-cell number at the ... Several genes
involved in pancreas development encode proto-oncogenes (PBX1, MEIS, SHH ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

Development and diseases of the pancreas Section Editors: Roderick R McInnes, e-mail: mcinnes@ … - Full text - MIT Libraries
KAJ andA Grapin-Botton - Clinical Genetics, 2002 - blackwell-synergy.com
... Interestingly, in Pax4 / Pax6 / double-mutant mice there is a complete absence of ...
genes involved in pancreas development encode proto-oncogenes (PBX1, MEIS, SHH ...
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A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... protein 1 YY1 01 Yin and Yang 1 One of the best examples of this phenomenon is PAX4
01, with a ... PBX1 02 Homeo domain factor Pbx-1 Core should be CAATC not CAAT ...
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G ENES, S IGNALS, AND L INEAGES IN P ANCREAS D EVELOPMENT - Full text - MIT Libraries
LC Murtaugh, DA Melton - Annual Review of Cell and Developmental Biology, 2003 - astro.annualreviews.org
... A similar albeit less severe phenotype is seen in mice lacking the homeodomain gene
Pbx1, which exhibit severe hypoplasia of the dorsal pancreas, coupled with ...
Cited by 18 - Web Search - astro.annualreviews.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transgenic Tagging Defining Pancreatic Pedigrees - Full text - MIT Libraries
P Cancer, G Expression, E Tumors - Ann. NY Acad. Sci, 2004 - annalsnyas.org
... Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes ...
The Pax4 gene is essential for differentiation of insulin-producing beta ...
Web Search - annalsnyas.org - ncbi.nlm.nih.gov

The PAX6 gene is activated by the basic helix–loop–helix transcription factor NeuroD/BETA2 - Full text - MIT Libraries
E Marsich, A Vetere, M Di Piazza, G Tell, S … - Biochem J, 2003 - bj.portlandpress.com
... spatial expression patterns [4]. Two members of the PAX gene family, PAX4 and PAX6 ...
potential binding sites for bHLH (E boxes), a binding site for Pbx1 and two ...
Cited by 4 - View as HTML - Web Search - biochemj.org - biochemj.org - ncbi.nlm.nih.gov - all 5 versions »

Developmental Biology of the Pancreas
PLH Merino - Cell Biochemistry and Biophysics, 2004 - biomed.humanapress.com
... (71) Pbx1 Hypoplasia (16) Nkx2.2 Immature β-cells (72) Page 10. as well as Pax6
and Pax4, are necessary for the differentiation of islet endocrine cells. ...
Web Search - neurosci.humanapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

The Transcriptional Repressor Nkx6. 1 Also Functions as a DNA Context-Dependent Transcriptional … - Full text - MIT Libraries
T Iype, DG Taylor, SM Ziesmann, JC Garmey, H … - Molecular Endocrinology, 2004 - mend.endojournals.org
... the paired-homeodomain factor Pax4 directly binds to the pax4 promoter and represses ...
Kim SK, Selleri L, Lee JS, Zhang AY, Gu X, Jacobs Y, Cleary ML 2002 Pbx1 ...
Cited by 1 - Web Search - mend.endojournals.org

Development of cell markers for the identification and expansion of islet progenitor cells
YQ Zhang, N Sarvetnick - Diabetes/Metabolism Research and Reviews, 2003 - doi.wiley.com
... Tran- scription factors expressed in pancreatic progenitor cells include PDX-1,
Hlxb9 PTF1-p48 PBX1, Nkx2.2, Nkx6.1, Isl-1, Pax4, Pax6, Ngn3 and Beta2/NeuroD. ...
Cited by 7 - Web Search - joplink.net - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Contrasting patterns of expression of transcription factors in pancreatic alpha and beta cells - Full text - MIT Libraries
J Wang, G Webb, Y Cao, DF Steiner - Proc. Natl. Acad. Sci. USA, 2003 - pnas.org
... Factors such as Pax-6 and Pbx1, which are expressed in differentiated and cells ... Pax4,
which is restricted to pancreatic progenitors and is very low in adult ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

The Development of Beta-cell Mass: Recent Progress and Potential Role of GLP-1 - Full text - MIT Libraries
DA Stoffers - Hormone and Metabolic Research, 2004 - thieme-connect.com
... Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes
diabetes mellitus ... Pineda B, Chowdhury K, Torres M, Gruss P. The Pax4 gene is ...
Cited by 2 - Web Search - thieme-connect.com - ncbi.nlm.nih.gov

Gene regulatory factors in pancreatic development - Full text - MIT Libraries
J Jensen - Developmental Dynamics, 2004 - doi.wiley.com
... neurogenin3 (atoh5) fol- lowed by several genes that may be common between endocrine
cells (eg, Pax6, Isl1, NeuroD), or cell-specific (eg, Pax4, Brn4), among ...
Cited by 14 - Web Search - pi.be - ncbi.nlm.nih.gov

The Transcriptional Repressor Nkx6. 1 Also Functions as a Deoxyribonucleic Acid Context-Dependent … - Full text - MIT Libraries
T Iype, DG Taylor, SM Ziesmann, JC Garmey, H … - Molecular Endocrinology - mend.endojournals.org
... Selleri L, Lee JS, Zhang AY, Gu X, Jacobs Y, Cleary ML 2002 Pbx1 inactivation disrupts ...
Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P 1997 The Pax4 gene is ...
Cited by 2 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity - Full text - MIT Libraries
B Kammandel, K Chowdhury, A Stoykova, S Aparicio, … - Dev. Biol, 1999 - fbmc.fcen.uba.ar
Page 1. Distinct cis-Essential Modules Direct the Time– Space Pattern of
the Pax6 Gene Activity Birgitta Kammandel, Kamal Chowdhury ...
Cited by 66 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TranSignal TM GR-TF Interaction Arrays
PU Manual - panomics.com
Page 1. TranSignal TM GR-TF Interaction Arrays GR-TFCat. # MA5061, MA5062 &
MA5063 Product User Manual Released 07/29/04 Panomics, Inc. ...
View as HTML - Web Search - biocat.de

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays Cat. # MA1010, MA1011, MA1012 Product User
Manual, MA1013 & MA1014, MA1015 Released 09/28/04 Panomics, Inc. ...
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TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays (Column Separation Version) Cat. #
MA1210, MA1211, MA1212l, MA1213 & MA1214, MA1215 Product ...
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FGFs and Wnts in pancreatic growth and
S Papadopoulou - diva-portal.org
... cell proliferation that is mediated partly through its interaction with Pbx1. 18
Page 19. ... Pax genes Pax4 and Pax6 are both independent members of the paired-box ...
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Conserved and muscle group-specific gene expression patterns shape postnatal development of the … - Full text - MIT Libraries
G Cheng, AP Merriam, B Gong, P Leahy, S Khanna, JD … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... enriched genes (eg, Pax4, 62%; Pitx2, 15%; Nkx2.5, 13.5%; Supplementary Table 6 ... 15%;
Tfap2a, 10%; Pbx1, 8%; Hnf3b, 6%) also were detected at moderate frequency ...
Web Search - dx.doi.org - ncbi.nlm.nih.gov - ijmm.org - all 5 versions »

Ectopic expression of the beta-cell specific transcription factor Pdx 1 inhibits glucagon gene … - Full text - MIT Libraries
B Ritz-Laser, BR Gauthier, A Estreicher, A Mamin, … - Diabetologia, 2003 - springerlink.com
... In acinar cells, Pdx1 associates with Pbx1 and Meis2 on the B element of the elastase
I gene [40] and endocrine-specific complexes consist of Pdx1/Pbx, Pdx1/Pax ...
Cited by 1 - Web Search - medecine.unige.ch - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Etude des fonctions pancreatiques du recepteur nucleaire orphelin Liver Receptor Homolog-1 (LRH-1) …
D de These, PJ AUWERX - eprints-scd-ulp.u-strasbg.fr
Page 1. UNIVERSITE STRASBOURG I - LOUIS PASTEUR Institut de Génétique et
de Biologie Moléculaire et Cellulaire THESE Pour obtenir ...
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Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells
S Material, Y Hori, X Gu, X Xie, S Kim - pubmedcentral.nih.gov
... Expression of Pax4 in embryonic stem cells promotes differentiation of Nestin ... Pbx1
inactivation disrupts pancreas development and in Ipf1-deficient mice ...
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Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells
Y Hori, X Gu, X Xie, SK Kim - PLoS Med - dx.doi.org
... Find this article online; Blyszczuk P, Czyz J, Kania G, Wagner M, Roll U, et al.
(2003) Expression of Pax4 in embryonic stem ... (2002) Pbx1 inactivation disrupts ...
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Molecular and biochemical analysis of the MODY syndromes - Full text - MIT Libraries
WE Winter - Pediatric Diabetes, 2000 - dx.doi.org
... islet. Within the islet, Pax4 is important for beta and delta cell formation
whereas Pax6 is important for alpha cell development. ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

1.1 Mechanismen der Steuerung der Embryonalentwicklung
B Christ, B Brand-Saberi - springeronline.com
Page 1. 1.1 Mechanismen der Steuerung der Embryonalentwicklung Bodo Christ
und Beate Brand-Saberi Wer weiter nichts als die Kreaturen ...
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