… genes: a mole cu lar link betwe en deve lop ment and cancer Ge nes home o box: uma rela cao mole cu …
IDUCTI ON - Pesqui Odontol Bras, 2003 - scielo.br
... ra tem mostra do um núme ro cada vez mai or de traba lhos rela- ci o ... A genomic fusion
in frame between the nucleoporin gene NUP98 and the HOXA9 gene was shown ...
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Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... PBX1,TR ALPHA, Malic Enzyme, HOXA9, HOXA11, HOXD12, HOXB13, SST, RB1, E2F1, HOXA10 ...
GRB2, LCK, VIL2, ERBB2, FYN, CD3Z, FGF2, FGFR1, NUDT6, RELA, HMGA1, EZRIN, MSN ...
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Genomic organization of the Hoxa4-Hoxa10 region from Morone saxatilis: implications for Hox gene …
EA Snell, JL Scemama, EJ Stellwag - J. Exp. Zool.(Mol. Dev. Evol.), 1999 - doi.wiley.com
... gene and the putative Hoxa7 exon1 sequence is similar to the Hoxa9-Hoxa7 intergenic ...
If there is a causal rela- tionship, we hypothesize that the extent of clus ...
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Homeobox genes: a molecular link between development and cancer
I PhD, II Dentist, TIIID Student - scielo.br
... Genes homeobox: uma rela molecular entre o desenvolvimento eo c er. ... A genomic
fusion in frame between the nucleoporin gene NUP98 and the HOXA9 gene was ...
Cached - Web Search - scielo.br

Regulation of HoxA expression in developing and regenerating axolotl limbs - Full text - MIT Libraries
DM Gardiner, B Blumberg, Y Komine, SV Bryant - Development, 1995 - dev.biologists.org
... to changes in Hox gene expression, further evidence of the rela- tionship between
Hox ... the expression of two 5′ members of the HoxA complex, HoxA13 and HoxA9. ...
Cited by 56 - Web Search - blumberg-serv.bio.uci.edu - dev.biologists.org - ncbi.nlm.nih.gov

MOLECULAR TARGETS FOR THERAPY (MTT)
J Roche, C Zeng, A Baron, S Gadgil, RM Gemmill, I … - Leukemia, 2004 - nature.com
... 1,2 Other than chromosomal rearrangements, rela- tively little is known of the ... Paralogs
(eg, HOXA9, B9, C9, D9) are more closely related than adjacent genes ...
Web Search

Characterisation of Hoxa gene expression in the chick limb bud in response to FGF - Full text - MIT Libraries
N Vargesson, K Kostakopoulou, G Drossopoulou, S … - Developmental Dynamics, 2001 - doi.wiley.com
... Expression of genes Hoxa9 through Hoxa13, and Hoxd9 through Hoxd13, in the vertebrate ...
1A,B), only a rela- tively small reduction in the Hoxa11 gene expression ...
Cited by 5 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Therapeutic implications of cancer stem cells
M Al-Hajj, MW Becker, M Wicha, I Weissman, MF … - Curr Opin Genet Dev, 2004 - ufpel.edu.br
... Bmi-1 also plays a key role in malignant hematopoiesis as HOXA9/ MEIS 1 induced ... all
of the mutations could occur during the life of these rela- tively short ...
Cited by 19 - View as HTML - Web Search - biol.sc.edu - ingentaconnect.com - all 5 versions »

Alien invaders - Full text - MIT Libraries
PD Moore - Nature, 2000 - nature.com
... For example, high expression of the homeobox gene HOXA9, previously identi- fied
as a ... with certain plant roots, forming a mutually beneficial rela- tionship). ...
Cited by 1 - Web Search - nature.com

Complete mutation analysis panel of the 39 humanHOX genes
K Kosaki, R Kosaki, T Suzuki, H Yoshihashi, T … - Teratology, 2002 - doi.wiley.com
... as a first step toward comprehensive evaluation of the rela- tionship between ... before
the present study: HOXA1, HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10, HOXA11 ...
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cDNA Hox Sequences 3 0 of the Homeobox Isolated from the Sea Urchin Holopneustes purpurescens are …
VB MORRIS, J BRAMMALL, M BYRNE, M FROMMER - DNA Sequence, 2002 - dx.doi.org
... Hox genes have been recognized in sea urchins and their rela- tive positions ... The
HpHbox4 and TgHbox4 sea urchin sequences are aligned with Hoxa9, Hoxb9, Hoxc9 ...
Cited by 4 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Vertebrate limb development and possible clues to diversity in limb form - Full text - MIT Libraries
C Tickle - Journal of Morphology, 2002 - doi.wiley.com
... while proximal cells express only the more 3 genes, Hoxd9 and Hoxa9 (Izpisua-Belmonte ...
It is also rela- tively easy to explain loss of the most posterior digit ...
Cited by 5 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Hemophilia gene therapy: it’sa matter of expression - Full text - MIT Libraries
R Bhatia - BLOOD, 2004 - bloodjournal.org
... In this study, the authors have evaluated the rela- tive efficacy and safety ... transcript
was in- directly demonstrated by up-regulation of HOXA9 gene expression ...
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Hox cluster organization in the jawless vertebratePetromyzon marinus - Full text - MIT Libraries
A Force, A Amores, JH Postlethwait - Journal of Experimental Zoology, 2002 - doi.wiley.com
... ABD-B P09087; Dre Hoxa9b AAD15942; Hfr HoxD9 AAF44633; Hfr HoxA9 AAF44646; Bmo ... used
the fol- lowing convention to indicate phylogenetic rela- tionships: Square ...
Cited by 33 - Web Search - benaroyaresearch.org - benaroyaresearch.org - ncbi.nlm.nih.gov - all 5 versions »

Implication des genes Hox dans les processus d’organogenese chez les mammiferes
J Aubin, L Jeannotte - Medecine/Sciences, 2001 - ist.inserm.fr
... plexes adjacents, Antennapedia et bithorax (figure 1). Il existe une rela- tion
de co-linéarité entre la position relative de chaque gène au sein de ces ...
Cited by 4 - View as HTML - Web Search

A conceptual scale for correlating cytogenetic and physical maps - Full text - MIT Libraries
M Bina, J Young, EI Pares-Matos, F Alert - Cytogenetic and Genome Research, 2002 - content.karger.com
... A rela- tive scale can help with identifying the position of specific land- marks ...
197.8 TF HOXA9/HOX1G, Hox 1.7 mouse homolog, Abd-B Drosophila homolog 7p15 ...
Cited by 1 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Effects of HOX homeobox genes in blood cell differentiation - Full text - MIT Libraries
MC Magli, C Largman, HJ Lawrence - J Cell Physiol, 1997 - doi.wiley.com
... HOX gene knockouts reported in the literature, rela- tively little has been published ...
volves HOXA9, which, like HOXA10, is expressed in both the lin 0 fraction ...
Cited by 57 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with … - Full text - MIT Libraries
E Hedlund, SL Karsten, L Kudo, DH Geschwind, EM … - Journal of Neuroscience Research, 2004 - doi.wiley.com
... differentiation (Yaron et al., 2001), while overexpression of Hoxa9 or Hoxa10 pro ...
be conserved between mutant and wild-type samples; therefore rela- tively few ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TALE class homeodomain gene Irx5 is an immediate downstream target for Hoxb4 transcriptional … - Full text - MIT Libraries
C Theokli, MEK AS, R Morgan - Dev Dyn, 2003 - doi.wiley.com
... that Irx1 expression is re- pressed by BMP4, suggesting that there is a mutually
repressive rela- tionship between ... Hoxa9 osteopontin Secreted protein Shi et al ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

Progress in Hematology
A Iwama, H Oguro, M Negishi, Y Kato, H Nakauchi - Int J Hematol, 2005 - cardenjennings.metapress.com
... be due to a decreased number of B-cells that results in the rela- tive enrichment ...
defi- cient for PcG genes except for a slight increase in HoxA9 messenger RNA ...
Web Search

d’extraordinaires possibilites de traitement des maladies degeneratives. En effet, la capacite de …
M Tawk, S Vriz - MEDECINE/SCIENCES, 2003 - erudit.org
... C’est le cas, par exemple, des gènes HoxA9 et HoxA13 qui sont exprimés ... Marcus Singer
a montré une rela- tion directe entre le nombre de fibres nerveuses ...
View as HTML - Web Search - ist.inserm.fr - ist.inserm.fr

Molecular pathogenesis of MDS
H Hirai - Int J Hematol, 2002 - haem.nus.edu.sg
... proximately 5% of primary MDS and confers a rela- tively favorable prognosis. ...
p15;q11), and inv(11) (p15q22) result in generation of NUP98/HOXA9, NUP98/ HOXD13 ...
Cited by 3 - View as HTML - Web Search - ishapd.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Molecular control of vertebrate limb development, evolution and congenital malformations - Full text - MIT Libraries
MJ Cohn, PE Bright - Cell & Tissue Research, 1999 - springerlink.com
... It is noteworthy, however, that functional inactivation of Hoxa9, Hoxb9 or Hoxc9
individually results in axial skeletal defects, but limbs appear to develop nor ...
Cited by 17 - Web Search - zoo.ufl.edu - ncbi.nlm.nih.gov

Regeneration of the urodele limb: A review - Full text - MIT Libraries
HLD Nye, JA Cameron, EAG Chernoff, DL Stocum - Developmental Dynamics, 2003 - doi.wiley.com
Page 1. REVIEWS A PEER REVIEWED FORUM Regeneration of the Urodele Limb: A Review
Holly LD Nye, 1 Jo Ann Cameron, 1 Ellen AG Chernoff, 2 and David L. Stocum 2 * ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal …
YN Kobzev, J Martinez-Climent, S Lee, J Chen, JD … - GENES, CHROMOSOMES & CANCER, 2004 - doi.wiley.com
... (2004) who found, using microarray analysis, that trans- fecting the
NUP98–HOXA9 fusion gene into K562 cells up-regulated transcripts. ...
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Transcriptional Control of the Cell Cycle in Mammary Gland Development and Tumorigenesis
RD Coletta, P Jedlicka, A Gutierrez-Hartmann, HL … - Journal of Mammary Gland Biology and Neoplasia, 2004 - springerlink.com
... Current data support the argument that these rela- ... Whilethemammaryglandsofvirginm
icemutant for three paralogous Hox9 genes (Hoxa9, Hoxb9, and Hoxd9) are normal ...
Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin - Full text - MIT Libraries
K KAUSHANSKY, I LEMISCHKA - J. Immunol, 2005 - dx.doi.org
... Home page K. Kirito, N. Fox, and K. Kaushansky Thrombopoietin Induces HOXA9 Nuclear
Transport in Immature Hematopoietic Cells: Potential Mechanism by Which the ...
Web Search - dx.doi.org - pnas.org

Vertebrate limb development: from Harrison’s limb disk transplantations to targeted disruption of … - Full text - MIT Libraries
S Koussoulakos - Anatomy and Embryology, 2004 - springerlink.com
... the dorsal blas- topore lip cells in anurans (posterior to anterior) in rela- tion
to ... formation; however, the pattern of expres- sion of the genes Hoxa9-13 and ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TIF1 functions as a coactivator for C/EBP and is required for induced differentiation in the … - Full text - MIT Libraries
JW Rooney, KL Calame - GENES & DEVELOPMENT - bioscience.drexel.edu
... Hoxa9, when overexpressed, blocks myeloid dif- ferentiation (Calvo et al. ... For TIF1
Rz1, the antisense region corresponding from 907 to 1002 (rela- tive to the ...
Cited by 2 - View as HTML - Web Search

Text-Based Gene Profiling with Domain-Specific Views
P Glenisson, B Coessens, SV Vooren, Y Moreau, BD … - SWDB, 2003 - cs.uic.edu
... We note that, at this time, we chose to neglect the structure defining the rela-
tions between the objects, as well as the limited amount ... HOXA9 3205 NRF 55922 ...
Cited by 1 - View as HTML - Web Search

Ethidium Bromide Provides a Simple Tool for Identifying Genuine DNA-Independent Associations - Full text - MIT Libraries
J Lai, W Herr - Proceedings of the National Academy of Sciences - pnas.org
... Biol. Home page WF Shen, S. Rozenfeld, A. Kwong, LG Komuves, HJ Lawrence, and C.
Largman HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells Mol. ...
Web Search - adsabs.harvard.edu

Rare recurring balanced chromosome abnormalities in therapy-related myelodysplastic syndromes and …
AW Block, AJ Carroll, A Hagemeijer, L Michaux, K … - Genes Chromosomes Cancer, 2002 - doi.wiley.com
Page 1. Rare Recurring Balanced Chromosome Abnormalities in Therapy-Related
Myelodysplastic Syndromes and Acute Leukemia: Report From an International Workshop ...
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Molecular Cytogenetic Aspects of Hematological Malignancies: Clinical Implications
Z CHEN, AA SANDBERG - American Journal of Medical Genetics (Semin. Med. Genet.), 2002 - doi.wiley.com
Page 1. American Journal of Medical Genetics (Semin. Med. Genet.) 115:130–141
(2002) ARTICLE Molecular Cytogenetic Aspects of Hematological ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Effects of Tumor Necrosis Factor-{alpha}(TNF {alpha}) in Epidermal Keratinocytes Revealed Using … - Full text - MIT Libraries
T Banno, A Gazel, M Blumenberg - J Biol Chem, 2004 - jbc.org
... whereas NF B1 (p105/p50), NF B2 (p49/p100), RELA (p65), and ... TNF -induced transcription
factors and transcription regulators include MBOX1, HOXA9, MAFF, HDAC7B ...
Cited by 5 - Web Search - jbc.org - ncbi.nlm.nih.gov

Making Better Drugs for Children with Cancer
PC Adamson, SL Weiner, JV Simone - ipcr.us
... TEL-AML1 <2,500 AML-ETO MLL (HOXA9, Meis1) Juvenile myelomonocytic leukemia Somatic
PTPN11 mutations NF1 GM-CSF hypersensitivity Overactivation of SHP ...
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Jun Dimerization Protein 2: A Multifunctional Transcription Factor in Mammalian Cells
T Yamasaki, M Noguchi, B Liu, K Nakade, PC Wang, T … - Current Genomics, 2005 - ingentaconnect.com
... Fra-1 and Fra-2, which lack potent transactivation domain, have rela- tively weak ...
with acute myelogenous leukemia (AML) who express high levels of HoxA9 [41]. ...
Web Search

Targeted transcriptional repression of Gfi 1 by GFI 1 and GFI 1 B in lymphoid cells - Full text - MIT Libraries
LL Doan, SD Porter, Z Duan, MM Flubacher, D … - Nucleic Acids Research, 2004 - nar.oupjournals.org
... Additional putative regulatory sites include recognition sequences for
E4BP4/NFIL3, HoxA9, SP-1, and the Ets factors ETS1 and ELK1. ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

TIF 1 beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in … - Full text - MIT Libraries
JW Rooney, KL Calame - Genes & Development, 2001 - genesdev.org
... leukemia (Tamura et al. 2000 ). Hoxa9, when overexpressed, blocks myeloid
differentiation (Calvo et al. 2000 ). Our objective was ...
Cited by 1 - Web Search - genesdev.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

AML M 3 and AML M 3 variant each have a distinct gene expression signature but also share patterns …
T Haferlach, A Kohlmann, S Schnittger, M Dugas, W … - Genes Chromosomes and Cancer, 2005 - doi.wiley.com
... the relation was strongest to AML M3v (Table 3). Significant rela- tionships with ...
genes in APL included CD86, CDW52, CSPG2, CTSS, DEFA4, HOXA9, HOXA10, MEIS1 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

BIOINFORMATICS
M Masseroli, P Cerveri, PG Pelicci, M Alcalay - BIOINFORMATICS, 2003 - bioinformatics.oupjournals.org
... We designed a database schema that can aggregate and store in a rela- tional database
all the heterogeneous data extracted from different HTML pages and ...
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Regulation of vertebrate homeobox-containing genes by morphogens
F MAVILIO - European Journal of Biochemistry, 1993 - blackwell-synergy.com
... 13 12 11 Hoxa-11 HOXCll Hoxc-11 HOXDll Hoxd-11 HOXAlO Hoxa-l 0 HOXClO 10
Hoxc-10 HOXDlO Hoxd-10 HOXA9 noxa -9 9 HOXB9 Hoxb-9 XlHbox6 HOXC9 ...
Cited by 30 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Amphibian Limb Regeneration: Rebuilding a Complex Structure - Full text - MIT Libraries
JC Biol, AJ Pathol, C Physiol - J. Cell Biol, 1993 - sciencemag.org
... be- tween Hox gene expression and positional identity is not understood either for
limb development or regeneration, the expres- sion of HoxA9 and A13 in the ...
Web Search

Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte …
C Kappen - American Journal of Hematology, 2000 - doi.wiley.com
... were determined on NIP-BSA (10 µg/ml)-coated plates rela- tive to ... the homeobox gene
HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis. ...
Cited by 13 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Cytogenetic and Molecular Genetic Evolution of Philadelphia-Chromosome-Positive Chronic Myeloid …
BJTFF Mitelman - content.karger.com
Page 1. Bain BJ (ed): Chronic Myeloproliferative
Disorders. Basel, Karger, 2003, pp 44–61 ...
Web Search - content.karger.com

Hedgehog signaling in mouse mammary gland development and neoplasia
MT Lewis - J. Mammary Gland Biol. Neoplasia, 2001 - springerlink.com
... During virgin stages, Ihh expression was rela- tively low in body cells of the terminal
end bud and low-to-undetectable in cap cells and differentiating ...
Cited by 7 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Developmental morphology of the axial skeleton of the zebrafish, Danio rerio(Ostariophysi: … - Full text - MIT Libraries
NC Bird, PM Mabee - Developmental Dynamics, 2003 - doi.wiley.com
Page 1. ARTICLE Developmental Morphology of the Axial Skeleton of the Zebrafish,
Danio rerio (Ostariophysi: Cyprinidae) Nathan C. Bird* and Paula M. Mabee* ...
Cited by 2 - Web Search - usd.edu - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

GENE CO-OPTION IN PHYSIOLOGICAL AND MORPHOLOGICAL EVOLUTION - Full text - MIT Libraries
JR True, SB Carroll - Annual Review of Cell and Developmental Biology, 2002 - cellbio.annualreviews.org
Page 1. Annu. Rev. Cell Dev. Biol. 2002. 18:53–80 doi: 10.1146/annurev.cellbio.
18.020402.140619 Copyright c 2002 by Annual Reviews. ...
Cited by 25 - Web Search - cephbase.com - cephbase.utmb.edu - cephbase.dal.ca - all 9 versions »

Biology of hematopoietic stem cells - Full text - MIT Libraries
M Kondo, AJ Wagers, MG Manz, SS Prohaska, DC … - Annu. Rev. Immunol, 2003 - uiowa.edu
... HOXB4, as well as HOXA9, also enhances HSC ex- pansion in vivo when introduced via
retroviral transduction into HSCs prior to transplantation (54, 57, 101). ...
Cited by 82 - View as HTML - Web Search - phyto.annualreviews.org - uiowa.edu - ncbi.nlm.nih.gov

Issues in Development
MAS MOORE - dx.doi.org
Page 1. STEM CELLS AND DEVELOPMENT 13:1–21 (2004) © Mary Ann Liebert, Inc. Issues
in Development Commentary The Role of Cell Migration in the Ontogeny of the ...
Web Search - liebertonline.com - liebertonline.com

Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
Page 1. HEMATOPOIESIS Novel transcription factors in human CD34 antigen–positive
hematopoietic cells Ignatius Gomes, Tiffany T. Sharma ...
Cited by 3 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »