Effect of Topical PPARss/‰ and PPARA Agonists on Plaque Psoriasis - Full text - MIT Libraries
SKJH Saurat - Dermatology, 2003 - content.karger.com
... PPARß/‰ is the most ubiquitously expressed isotype among the three, but rela- tively
little is known about its functions due to the lack of identification ...
Web Search - content.karger.com

Species differences in peroxisome proliferation; mechanisms and relevance - Full text - MIT Libraries
AI Choudhury, S Chahal, AR Bell, SR Tomlinson, RA … - Mutat Res, 2000 - dmg.nott.ac.uk
... These species have a functional PPARa, and it remains a challenge to determine what ...
w x9 DS Marsman, RC Cattley, JG Conway, JA Popp, Rela- tionship of hepatic ...
Cited by 13 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Evidence for substantial fine-scale variation in recombination rates across the human genome - Full text - MIT Libraries
DC Crawford, T Bhangale, N Li, G Hellenthal, MJ … - Nature Genetics, 2004 - nature.com
... PLAUR PLG PON1 PON2 PPARA PPARG SERPINA5 ... PLAT PLAUR PLG PON1 PON2 PPARA PPARG SERPINA5
PROS1 PROC PROZ SELP REN SFTPA1 SFTPA2 SFTPD SMP1 STAT4 TFPI TGFB3 TIRAP ...
Cited by 33 - Web Search - nature.com - stat.washington.edu - ncbi.nlm.nih.gov

Distribution of peroxisome proliferator-activated receptors(PPARs) in human skeletal muscle and … - Full text - MIT Libraries
M Loviscach, N Rehman, L Carter, S Mudaliar, P … - Diabetologia, 2000 - springerlink.com
... A statistically significant inverse rela- tion was detected between muscle PPARg
protein and ... Fig.2. A Expression of PPARa (top panel), PPARb (middle panel) and ...
Cited by 45 - Web Search - ncbi.nlm.nih.gov

Peroxisome Proliferator-Activated Receptor A Regulates Eosinophil Functions: A New Therapeutic … - Full text - MIT Libraries
SUYMH Kayaba, H Oyamada, AKAUN Saito, J Chihara - Int Arch Allergy Immunol, 2004 - content.karger.com
... J, Le- seche G, Aubier M, Pretolani M: Regulation of peroxisome proliferator-activated
receptor Á expression in human asthmatic airways: Rela- tionship with ...
Web Search - content.karger.com

Methods for Large-Scale Mining of Networks of Human Genes
TK Jenssen, LMJ Oeberg, ML Andersson, J Komorowski - Proceedings SIAM Conference on Data Mining (SDM, 2001), 2001 - idi.ntnu.no
... UCP2 is found at PubGene distance 2 from both PPARA and PPARD and CD36 at ... SCI neighbours
we also observe many genes that have a less specific rela- tionship to ...
Cited by 5 - View as HTML - Web Search - egeen.ee - lcb.uu.se - cs.ubc.ca - all 6 versions »

Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid … - Full text - MIT Libraries
N Roglans, M Vazquez-Carrera, M Alegret, F Novell, … - Eur J Clin Pharmacol, 2004 - springerlink.com
... type and truncated form of PPARa and enzymes associated with PPARa activation as ...
All treatments reduced the expression of CYP7A1 rela- tive to placebo group (50 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Thiazolidinedione Induces Apoptosis and Monocytic Differentiation in the Promyelocytic Leukemia Cell … - Full text - MIT Libraries
NHTY Yi-ming, MK Muta, TURTH Nawata - Oncology, 1999 - content.karger.com
... triplicate dishes. Letters (a–c) above the error bars indicate the rela-
tionship between the different experiment groups. Similar ...
Cited by 22 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

An integrative genomics approach to the reconstruction of gene networks in segregating populations - Full text - MIT Libraries
J Zhu, PY Lum, J Lamb, D GuhaThakurta, SW Edwards, … - Cytogenetic and Genome Research, 2004 - content.karger.com
... allowed the mice to reach a new steady state with respect to Ppara activity, all ...
Red indicates a gene is up regulated rela- tive to the reference pool, green ...
Cited by 6 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions »

Insulin Resistance and Insulin Sensitizers
MSH Haering - Horm Res, 2001 - content.karger.com
Page 1. Sensitivity to Growth Hormone Horm Res 2001;55(suppl 2):3–13 Insulin
Resistance and Insulin Sensitizers Michael Stumvoll Hans Häring ...
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Quantitative proteomic analysis of mouse liver response to the peroxisome proliferator … - Full text - MIT Libraries
N Macdonald, S Chevalier, R Tonge, M Davison, R … - Archives of Toxicology, 2001 - springerlink.com
... their rela- tive expression on comparison of wild-type and null mice suggesting
regulation by endogenous ligands or possibly regulation by non-liganded PPARa. ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - csa.com

Peroxisome proliferative drugs do not induce an increase of rat mevalonate pyrophosphate … - Full text - MIT Libraries
A Michihara, M Sawamura, Y Yamori, K Akasaki, H … - Biol Pharm Bull, 2003 - bpb.pharm.or.jp
... 13) From these data, the rela- tionship between peroxisome proliferation and ... to activate
peroxisome proliferator-acti- vated receptor alpha (PPARa), a member ...
Web Search - ncbi.nlm.nih.gov

Dietary trans octadecenoic acids upregulate the liver gene encoding Peroxisome Proliferator- …
KT Selberg, CR Staples, ND Luchini, L Badinga - journals.cambridge.org
... palmitoyl- transferase 1 (CPT1), microsomal triglyceride transfer protein (MTP)
and peroxisome proliferator- activated receptor alpha (PPARa) were examined in ...
Web Search - journals.cambridge.org

Causation of type 2 diabetes—the Gordian knot unravels - Full text - MIT Libraries
R Taylor - N Engl J Med, 2004 - fsm.ac.fj
... in- volving PGC-1? What is the dose–response rela- tionship between the ... now known
to be agonists of peroxisome-prolif- erator–activated receptor a (PPARa)? ...
Cited by 15 - View as HTML - Web Search - courses.mcb.arizona.edu - dx.doi.org - content.nejm.org - all 7 versions »

Novel Role of Oxidants in the Molecular Mechanism of Action of Peroxisome Proliferators
I Rusyn, ML Rose, HK Bojes, RG Thurman - Antioxidants & Redox Signaling, 2000 - dx.doi.org
... is known that humans have less than one- tenth the levels of PPARa expression observed ...
Reddy and Lalwani, 1983) and it has been suggested that a direct rela- ...
Cited by 15 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Role of redox-regulated transcription factors in inflammation, aging and age-related diseases
Y Lavrovsky, B Chatterjee, RA Clark, AK Roy - Exp Gerontol, 2000 - aging.pharm.pusan.ac.kr
... Functional antagonism between GR and the RelA subunit of NF-kB is due to their ...
pro-inflammatory agent leukotriene B 4 (LTB 4 ) is a natural ligand for PPARa. ...
Cited by 49 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

HYPERLIPIDIC DIETS INDUCE EARLY ALTERATIONS O. THE VITAMIN A SIGNALLING PATHWAY IN RAT COLONIC … - Full text - MIT Libraries
R Groubet, V Pallet, B Delage, A Redonnet, P … - ENDOCRINE REGULATIONS, 2003 - elis.sk
... Thus, the rela- tive availability of RXR in the cell could result from a complex ...
fatty acids (PU.A (n-6)) induced an increased expression of PPARa and a ...
View as HTML - Web Search - sav.sk - elis.savba.sk - aepress.sk - all 6 versions »

Magnon damping, spin stiffness, and dynamic scaling in the two-dimensional quantum Heisenberg … - Full text - MIT Libraries
P Kopietz, G Castilla - Physical Review B - link.aps.org
... Note, however, that the linear magnon dispersion rela- tion of the QAFM implies
a different ... 43 Jk =-E eikri then be written as para( T) =lim( OlimkO pPara( k, A ...
Cited by 9 - Web Search - adsabs.harvard.edu - ncbi.nlm.nih.gov

3rd Teupitzer Colloquium 2000 Basic Research in Endocrine Dermatology
CC Zouboulis, M Fritsch, H Seltmann, S Fimmel, CE … - content.karger.com
Page 1. 3rd Teupitzer Colloquium 2000 Basic Research in Endocrine Dermatology
September 17–20, 2000 Teupitz Castle Hotel (near Berlin) ...
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Population prevalence of APOE, APOC3 and PPAR-a mutations associated to hypertriglyceridemia in … - Full text - MIT Libraries
J Girouard, MC Vohl, J Bergeron, F Rousseau, P … - J Hum Genet, 2004 - springerlink.com
... E (APOE) (C112R and C158R), the apolipoprotein CIII (APOC3) (C-482T and C3238G)
and the peroxisome proliferator-activated receptor alpha (PPARa) (L162V) genes. ...
Web Search

Ist die versehiedene Sehschiirfe unserer Haustiere dnrch die dioptrisehe Einrichtung ihrer Augen …
FW Krzywanek, M Glaub - springerlink.com
... 17 stellte noeh weitergehende Bereehnungen an; er erreehnete eine ,,rela- tive"
(in ... Sehschiir/e dutch eine Verschiedenheit des dioptrischen A ppara- tes des ...
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Chylomicron remnants and oxidised low density lipoprotein have differential effects on the … - Full text - MIT Libraries
KV Batt, L Patel, KM Botham, KE Suckling - Journal of Molecular Medicine, 2004 - springerlink.com
... net result of these effects is that activation of PPARd, but not PPARa or g ... macrophages
as compared to monocytes are shown in Table 3. The rela- tive abundance ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Pharmacogenomics of lipid-lowering agents
MM Hoffmann, BR Winkelmann, H Wieland, W Maerz - Pharmacogenomics: The Search for Individualized Therapies - doi.wiley.com
... As bezafibrate is not PPARa-specific, but also interacts with PPARc and ... advantage
of providing more information on genotype–phenotype rela- tionships than ...
Cited by 1 - Web Search

Reversibility of the Chronic Effects of Di (2-ethylhexyl) phthalate
RM David, MR Moore, DC Finney, D Guest - Toxicologic Pathology, 2001 - dx.doi.org
... Data from PPARa -null mice suggests that cytoplasmic eosinophilia and hepatocyte
pigmentation ... Only the rela- tive liver weight for male Recovery animals was ...
Cited by 4 - Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - csa.com - Get it from MIT Libraries

Enhanced expression of peroxisome proliferator-activated receptor gamma in epithelial ovarian … - Full text - MIT Libraries
GY Zhang, N Ahmed, C Riley, K Oliva, G Barker, MA … - British Journal of Cancer, 2005 - nature.com
... PPARa has been shown to be expressed in colon tumours and overexpressed in ... inflammation
by regulating nuclear-cytoplasmic shuttling of PPAR- gamma and RelA. ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov

PPAR {alpha} Activators Inhibit Vascular Endothelial Growth Factor Receptor-2 Expression by … - Full text - MIT Libraries
M Meissner, M Stein, C Urbich, K Reisinger, G … - Circulation Research, 2004 - circresaha.org
... Coimmunoprecipitation of Sp1/PPARa For Sp1 immunoprecipitation, 5x10 6 cells were
lysed ... Sp1 consensus-oligonucleotide (Promega), PPAR , Sp1, Sp3, or RelA/NF- B ...
Cited by 2 - Cached - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 7 versions »

The extent and importance of intragenic recombination
E de Silva, LA Kelley, M Stumpf - Hum. Genomics, 2004 - ingentaconnect.com
... pfc, plau, procr, thbd, tirap, tnfaip2, tnfaip1, vtn, proz1, rela, scya2, serpinc1 ...
il1r2, il1rn, il4r, il7r, il15ra, il21r, kng, plat, pon2, ppara, proz, selplg ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Unique renal tubule changes induced in rats and mice by the peroxisome proliferators 2, 4- …
K Ozaki, JF Mahler, JK Haseman, CR Moomaw, ML … - Toxicologic Pathology, 2001 - taylorandfrancis.metapress.com
... c pattern of expression is consistent with a role for PPARa , but not ... and electron
microscopic characterizations to elucidate its possible rela- tionship to ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

NF-kB functions as both a proapoptotic and antiapoptotic regulatory factor within a single cell type - Full text - MIT Libraries
B Lin, C Williams-Skipp, Y Tao, MS Schleicher, LL … - Cell Death Differ, 1999 - nature.com
... Subsequently, it was demonstrated that reintroduction of relA to immortalized
hepatocytes derived ... a role in apoptosis mediated by engagement of PPARa and PPARg ...
Cited by 51 - Web Search - nature.com - ncbi.nlm.nih.gov

Unique Renal Tubule Changes Induced in Rats and Mice by the Peroxisome Proliferators 2, 4- …
K Ozaki, JF Mahler, JK Haseman, CR Moomaw, ML … - Toxicologic Pathology, 2001 - dx.doi.org
... c pattern of expression is consistent with a role for PPARa , but not ... and electron
microscopic characterizations to elucidate its possible rela- tionship to ...
Web Search - ingentaconnect.com - csa.com

N. D. Chuvylkin and G. M. Zhidomirov UDC 539.193
SOFG PARAMETERS - springerlink.com
... HI constants are given in Table 3. A comparison of the rela- tive total ... constants
(Qi_iPara/QHOrtho) and the ratio of the spin populations (Ppara/Portho) for ...
Web Search

Konsensuspapier der DA CH.-Liga Homocystein ueber den rationellen klinischen Umgang mit Homocystein, …
DH als unabhaengiger Risikofaktor - dach-liga-homocystein.org
... L, the risk increase follows a linear dose-response rela- tionship with ... Cobaltoxidation,
Cobalamin und MS-Inaktivierung Lipidsenker Fibrate ­ PPARa-Aktivierung ...
View as HTML - Web Search - 149.148.224.4 - journals.imc.akh-wien.ac.at - kup.at

Age-related phenotypes in the staggerer mouse expand the ROR· nuclear receptor’s role beyond the …
CI Jarvis, B Staels, B Brugg, Y Lemaigre-Dubreuil, … - Mol Cell Endocrinol, 2002 - npa.snv.jussieu.fr
... such as the glucocorticoid receptor (Auphan et al., 1995), PPARa and PPARg ... involved
in a characterised mutation, provide a complementary rela- tionship between ...
Cited by 16 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

High evolutionary rates in nuclear genes of squamates
S Hughes, D Mouchiroud - J molec Evol, 2001 - springerlink.com
... chose to take a mammal representative to compute distances because, as we said above,
phylogenetic rela- tionships between ... ppara 642 0.0144 0.0053 + 0.1011 NS ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

HMG-CoA reductase inhibitor pharmacogenomics: overview and implications for practice
I Zineh - Future Cardiology, 2005 - futuremedicine.com
... 142910 606945 Lipoprotein metabolism ABCA1 ABCG5 ABCG8 APOA1 APOB APOC2 APOE CETP
LCAT LEPR LIPC MTP PPARA PPARD PPARG SOAT1 SCAP SCARA3 SCARB1 SREBF1 SREBF2 ...
Web Search - futuremedicine.com

Peroxisome Proliferator-activated Receptors in Atherosclerosis and Inflammation--An Update
CS Elangbam, RD Tyler, RM Lightfoot - Toxicologic Pathology, 2001 - dx.doi.org
... the transcriptional activity of the NF-j B P65/RelA subunits, suggesting that ...
proliferator-activated receptors (PPARs): Tissue distribution of PPARa , b , and ...
Cited by 15 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Maternal low protein diet in rats programmes fatty acid desaturase activities in the offspring - Full text - MIT Libraries
SE Ozanne, ND Martensz, CJ Petry, CL Loizou, CN … - Diabetologia, 1998 - springerlink.com
... enzyme could contribute to a genetic basis of Type II diabetes [3]. Epidemiological
studies have shown strong rela- tions between ... 1996) The PPARa-leukotriene B ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov

Aplicaciones de un modelo borroso para el calculo de puntos de equilibrio
A Economico - analisiseconomico.com.mx
... Esta expresión representa la relación borrosa O = g(p), es decir la rela- ción oferta ...
El objetivo de este problema es encon- trar el precio Ppara el cual la ...
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Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor jB in …
K Kristiansen - ingentaconnect.com
... The p65-dependent repression of PPARd- but not PPARa- or PPARc- mediated
transactivation was partially relieved by forced expression of the coactivators ...
Web Search

PPARg, the ultimate thrifty gene - Full text - MIT Libraries
J Auwerx - Diabetologia, 1999 - springerlink.com
... expression of PPARg during development in mammals but in Xenopus, un- like PPARa
and b ... A change in the rela- tive expressions of RAR and PPARg in the differen ...
Cited by 29 - Web Search

Glucocorticoids and bone: cellular, metabolic and endocrine effects
M Doga, S Bonadonna, A Giustina - hormones.gr
... These pulsatility studies examined the rela- tionship between PTH and glucocorticoids
in the context of PTH secretory dynamics, calling atten- tion to the need ...
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[BOOK] Bile Acids: From Genomics to Disease and Therapy
G Paumgartner, U Leuschner, D Keppler - 2003 - print.google.com
... mice' 8 .This paper revealed how loss of a major catabolic pathway affected cholesterol
metabolism in a mammal, and it formalized a collegial rela- tionship I ...
Web Search - Get it from MIT Libraries - Library Search

Drug-activated nuclear receptors CAR and PXR
P Honkakoski, T Sueyoshi, M Negishi - Annals of Medicine, 2003 - taylorandfrancis.metapress.com
... This ¯exibility and rela- tive lack of speci®c binding interactions,as compared ...
hepatocyte-speci®c abla- tion of RXRa expression up-regulates PPARa,FXR, and ...
Cited by 23 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Phosphorylation of PPARg via Active ERK1/2 Leads to its Physical Association With p65 and Inhibition … - Full text - MIT Libraries
F Chen, M Wang, JP O’Connor, M He, T Tripathi, … - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... The expression of each PPAR isoform varies from tissue to tissue. PPARa is expressed
in hepatocytes, cardiomyocytes, and proximal tubule cells of the kidney. ...
Cited by 12 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Bezafibrate induces acyl-CoA oxidase mRNA levels and fatty acid peroxisomal beta-oxidation in rat …
M Vazquez, N Roglans, A Cabrero, C Rodriguez, T … - Molecular and Cellular Biochemistry, 2001 - kluweronline.com
... Rela- tionship with their activity as peroxisome proliferators. ... SA, Willson TM:
Aureido-thioisobutiric acid (GW9578) is a subtype- selective PPARa agonist with ...
Cited by 3 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Dual Role of Oxidized LDL on the NF-KappaB Signaling Pathway
F Robbesyn, R Salvayre, A Negre-Salvayre - Free Radical Research, 2004 - dx.doi.org
... The Rel/NF-kB family consists of the members NF-kB-1 (p50/p105), NF-kB-2 (p52/p100),
p65 (RelA), RelB and c-Rel which form various ... [75 – 77] PPARa and PPARg ...
Cited by 3 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

SIGNAL TRANSDUCTION OF BARNACLE EGG-HATCHING PHEROMONE: PHARMACOLOGICAL ASSAYS INDICATE A …
AS CLARE - Journal of Chemical Ecology, 1999 - springerlink.com
... In conclusion, unlike most eicosanoids that act as autocoids, EHP is a rela- tively
stable metabolite ... The PPARA-leukotriene B4 pathway to inflammation control. ...
Cited by 1 - Web Search - kluweronline.com

The solution structure refinement of the paramagnetic reduced high-potential iron-sulfur protein I …
M PICCIOLI, A ROSATO - Eur. J. Biochem, 1996 - blackwell-synergy.com
... used to determine nuclear longitudinal relaxation rates from which ppara can be ... Since
the HiPIP is a rela- tively small paramagnetic protein, the difficulties ...
Cited by 20 - Web Search - ingentaconnect.com - content.febsjournal.org - ejbiochem.org - all 8 versions » - Get it from MIT Libraries

Down regulation of peroxisome proliferator-activated receptor expression by inflammatory cytokines … - Full text - MIT Libraries
T Tanaka, H Itoh, K Doi, Y Fukunaga, K Hosoda, M … - Diabetologia, 1999 - springerlink.com
... family of nuclear receptors comprising three subtypes of designated isoforms, PPARa,
PPARg and ... gands for PPARg and there seems to be a close rela- tion between ...
Cited by 7 - Web Search

[BOOK] Lipids and Vascular Disease
DJ Betteridge - 2000 - print.google.com
... subjects) The authors observed that, when compared to fast- ing TG, the magnitude
of postprandial lipaemia showed a much tighter inverse rela- tionship to high ...
Cited by 1 - Web Search - Get it from MIT Libraries