Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors … - Full text - MIT Libraries
MO Hottiger, LK Felzien, GJ Nabel - The EMBO Journal, 1998 - embojournal.npgjournals.com
... In support of this possibility, we demonstrate that RelA and Stat2 can compete directly
for p300 binding and, remarkably, that this competition dramatically ...
Cited by 40 - Web Search - emboj.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

RelA suppresses the Wnt/ß-catenin pathway without exerting trans-acting transcriptional ability - Full text - MIT Libraries
O Masui, Y Ueda, A Tsumura, M Koyanagi, M Hijikata … - Int J Mol Med, 2002 - 147.52.72.117
... because of limitation of CBP/p300, strong influence of transcriptional abilities
between RelA and p53 (28-30), HTLV-1 Tax and p53 (31), RelA and STAT2 (32), AP ...
Cited by 4 - View as HTML - Web Search - virology.med.uoc.gr - ncbi.nlm.nih.gov

Activation of multiple growth regulatory genes following inducible expression of IRF-1 or IRF/RelA … - Full text - MIT Libraries
H Nguyen, R Lin, J Hiscott - Oncogene, 1997 - nature.com
... inducible expression of IRF-1 or IRF/RelA fusion proteins ... STAT1. WAF1 levels were
also constitutively elevated in IRF-1 and IRF-1/RelA cells. ...
Cited by 34 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 … - Full text - MIT Libraries
MO Hottiger, GJ Nabel - J. Virol, 1998 - jvi.asm.org
... To confirm the specificity of the p300-Tat interaction, GST-Tat was also used in
binding studies with other proteins, including RelA and Stat2. ...
Cited by 88 - Web Search - jvi.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Inhibition of the RelA (p 65) NF-kappa B Subunit by Egr-1 - Full text - MIT Libraries
NR Chapman, ND Perkins - J Biol Chem, 2000 - jbc.org
... These observations suggest that Egr-1-mediated repression of RelA occurs through ...
Egr-1 from other transcription factors, such as p53 and Stat2, that inhibit NF ...
Cited by 26 - Web Search - jbc.org - ncbi.nlm.nih.gov

Requirement for STAT1 in LPS-induced gene expression in macrophages
Y Ohmori, TA Hamilton - J. Leukoc. Biol, 2001 - jleukbio.org
... In some experiments, rabbit antibody to NF- B1 (p50); RelA (p65); and STAT1,
STAT2, and ISGF3- (p48) were added prior to electrophoresis. ...
Cited by 46 - Web Search - jleukbio.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Stat2 Binding to the Interferon-Receptor 2 Subunit Is Not Required for Interferon-Signaling - Full text - MIT Libraries
VP Nguyen, AZM Saleh, AE Arch, H Yan, F Piazza, J … - J. Biol. Chem, 2002 - ucihs.uci.edu
... significant enhancement of IFN -dependent reporter gene activity rela- tive to ... observe
a consistent difference in the level of Stat2 tyrosine phosphorylation ...
Cited by 1 - View as HTML - Web Search

Meeting Report Second International Conference on Signal Transduction, Croatia May 2000 - Full text - MIT Libraries
Z Dembic - Scandinavian Journal of Immunology, 2000 - blackwell-synergy.com
... Active STAT2 recruits GCN5 factor, which in turn, recruits TAF II 130 creating the
TFTC factor (TAF II 130 ... NF- B is a dimer of two proteins p65(RelA) and p50. ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A ... IκB Family:
NFKB1, NFKB2, NFKBIA, NFKBIB, NFKBIL1, NFKBIL2, NFRKB, REL, RELA, RELB. ...
View as HTML - Web Search - eurogentec.be

A Translation of Statecharts to Esterel
SA Seshia, RK Shyamasundar, AK Bhattacharjee, SD … - World Congress on Formal Methods, 1999 - springerlink.com
... relations can be used to restrict input events and a typical exclusion rela- tion
is ... nothing halt emit S stat1; stat2 loop stat end present S then stat1 else ...
Cited by 10 - Web Search - tcs.tifr.res.in - www-2.cs.cmu.edu - portal.acm.org - all 6 versions »

How the sequestration of a protein interferes with its mechanism of action: example of a new family …
S Thebault, JM Mesnard - Current Protein and Peptide Science, 2001 - ingentaconnect.com
... κB family of proteins is composed of transcriptionally active p65/RelA, c- Rel ... ISGF3
is comprised of three protein subunits, STAT1, STAT2 and p48/ISGF3γ [53 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation of Type I Interferon Gene Expression by Interferon Regulatory Factor-3 - Full text - MIT Libraries
SL Schafer, R Lin, PA Moore, J Hiscott, PM Pitha - J Biol Chem, 1998 - jbc.org
... stimulate expression of IFN genes but can cooperate with RelA(p65) to ... IFN-treated
cells, interacts with phosphorylated STAT1 and STAT2 transcriptional factors ...
Cited by 90 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in … - Full text - MIT Libraries
T Ouchi, SW Lee, M Ouchi, SA Aaronson, CM Horvath - Cell, 2000 - dx.doi.org
... Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit J ... Kraus,
JF Lau, JP Parisien, and CM Horvath A Hybrid IRF9-STAT2 Protein Recapitulates ...
Cited by 87 - Web Search - pnas.org - pubmedcentral.nih.gov - medschool.mc.vanderbilt.edu - all 7 versions »

Intracellular signal transduction in eosinophils and its clinical significance
CK Wong, J Zhang, WK Ip, CWK Lam - Immunopharmacol Immunotoxicol, 2002 - taylorandfrancis.metapress.com
... JAK3 and Tyk2) and at least nine di€erent STATs (STAT1a, STAT1b, STAT2, STAT3, STAT3b ...
genes as a dimmer composed of two Rel family proteins: p50 and RelA (p65 ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Pre-and Post-processing Filters for Improvement of Blood Velocity Estimation
M Schlaikjer, JA Jensen - Ultrasonics Symposium, 2000 IEEE, 2000 - ieeexplore.ieee.org
... One set of rela- tions are the spatial and temporal derivatives. ... of using the optimal
scale factors for 15 dB on all the data sets are listed as stat2 in Table ...
Web Search - es.oersted.dtu.dk - es.oersted.dtu.dk - ieeexplore.ieee.org

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of … - Full text - MIT Libraries
JL Herrmann, FB Jr, S Brisbay, CJ Logothetis, TJ … - Oncogene, 1998 - nature.com
... E64 did not demonstrably a€ect either IkBa degradation or p65 RelA nuclear import ...
The levels of the p116 STAT2 or b-catenin proteins showed no signi®cant ...
Cited by 59 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Restoration of interferon responses of adenovirus E1A-expressing HT1080 cell lines by overexpression … - Full text - MIT Libraries
GT Leonard, GC Sen - J. Virol, 1997 - jvi.asm.org
... acti- vate ISGF-3, because both ISGF-3 , composed of STAT1 and STAT2, and ISGF ... in
the cellular level of p48 in both HeLa and HT1080 cells, the causal rela- FIG. ...
Cited by 42 - Web Search - jvi.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

SEDIMENTATION OF CHARGED PARTICLES AT LARGE PECLET NUMBER
L Zhang, C Zhang, W Liu, Y Ren - jproeng.com
... V D (8) The first two sets of equation system (5) determine rela- tive trajectories
of the two spheres in the absence of Brownian diffusion. ...
View as HTML - Web Search

Signaling Pathways Mediated by the TNF-and Cytokine-Receptor Families Target a Common cis-Element of … - Full text - MIT Libraries
S Gupta, D Xia, M Jiang, S Lee, AB Pernis - J. Immunol, 1998 - jimmunol.org
... were conducted as above by addition of either an antiserum against Stat2 or a ... that
the CD40-inducible complex contains both p50 and p65 (RelA) or antigenically ...
Cited by 18 - Web Search - jimmunol.org - cumc.columbia.edu - ncbi.nlm.nih.gov - all 8 versions »

Interferon {alpha} Activates NF-{kappa} B in JAK1-deficient Cells through a TYK2-dependent Pathway - Full text - MIT Libraries
CH Yang, A Murti, WJ Valentine, Z Du, LM Pfeffer - J. Biol. Chem, 2005 - jbc.org
... proteins (1–3). Upon JAK-mediated tyrosine phosphorylation, the STATs (STAT1, STAT2,
and STAT3 ... the various Rel proteins (p50, p52, c-Rel, v-Rel, RelA/p65, and ...
Web Search - jbc.org - ncbi.nlm.nih.gov

p 300 and CBP: Partners for life and death - Full text - MIT Libraries
A Giordano, ML Avantaggiati - Journal of Cellular Physiology, 1999 - doi.wiley.com
... For example, two transcrip- tion factors, Stat2 and the RelA (p65) subunit of NFkB,
recognize the same structural motif of p300, lying within the first cysteine ...
Cited by 104 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcription Factor Activation in Human Neutrophils
A Cloutier, PP McDonald - The Neutrophil, Basel: Karger, 2003 - content.karger.com
... in other leukocytes, a role for IFN-activated STAT1 (and perhaps STAT2 as well ...
Individual members comprise the p65/RelA, c-Rel, and RelB proteins, as well as ...
Cited by 1 - Web Search - content.karger.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Cells Previously Desensitized to Type 1 Interferons Display Different Mechanisms of Activation of … - Full text - MIT Libraries
S Sakamoto, J Qin, A Navarro, A Gamero, R Potla, T … - J Biol Chem, 2004 - jbc.org
... activated via IFN -stimulated formation of ISGF3, a heterotrimeric DNA binding com-
plex consisting of p48 (IRF9) and tyrosine-phosphory- lated Stat1 and Stat2 ...
Cited by 1 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Functional Interplay Between Nuclear Factor-kappaB and c-Jun Integrated by Coactivator p 300 … - Full text - MIT Libraries
SB Maggirwar, S Ramirez, N Tong, HA Gelbard, S … - Journal of Neurochemistry, 2000 - blackwell-synergy.com
... RelA has previously shown to bind to the same region of p300 as the unrelated
transcription factor Stat2 (the CH1 domain, at amino acids 302-442) (Hottiger et ...
Cited by 23 - Web Search - urmc.rochester.edu - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Chromatin-remodelling factor BRG 1 selectively activates a subset of interferon-α-inducible genes - Full text - MIT Libraries
M Huang, F Qian, Y Hu, C Ang, Z Li, Z Wen - Nature Cell Biology, 2002 - nature.com
... Here we report that BRG1 interacts with signal transducer and activator of
transcription 2 (STAT2) — a transcription factor that reg- ulates gene expression ...
Cited by 22 - Web Search - nature.com - ncbi.nlm.nih.gov

Global Effect of PEG-IFN- and Ribavirin on Gene Expression in PBMC In Vitro
MW Taylor, WM Grosse, JE Schaley, C Sanda, X Wu, … - Journal of Interferon & Cytokine Research, 2004 - dx.doi.org
Page 1. JOURNAL OF INTERFERON & CYTOKINE RESEARCH 24:107–118 (2004) © Mary Ann
Liebert, Inc. Global Effect of PEG-IFN-a and Ribavirin on Gene ...
Cited by 4 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, … - Full text - MIT Libraries
R Lin, C Heylbroeck, PM Pitha, J Hiscott - Mol. Cell. Biol, 1998 - mcb.asm.org
... which in IFN-treated cells interacts with phosphorylated STAT1 and STAT2 transcription
factors ... the IRF-3 DNA binding domain and the RelA(p65) transactivation ...
Cited by 164 - Web Search - pubmedcentral.nih.gov - hepcvets.com - ncbi.nlm.nih.gov - all 5 versions »

IFN-> super-induction of HLA class I expression by a variant thymoma cell line involves nuclear …
H Travers, J Girdlestone - doi.wiley.com
... Therefore, the DNA- binding complexes may represent c-Rel and RelA homo- dimers ... requires
all three components of ISGF3, ie STAT1, STAT2 and ISGF3 + (p48), while ...
Web Search

Transcriptional cross talk between NF-kappaB and p53 - Full text - MIT Libraries
GA Webster, ND Perkins - Mol Cell Biol, 1999 - mcb.asm.org
... shown that cross talk between E2F and p53 (40) or STAT2 and NF- B (29) occurs through
a similar mechanism. Although we have shown that p53 and RelA can bind ...
Cited by 172 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Mechanisms for Regulation of Cellular Responsiveness to Human IFN-1 a
SA Dupont, S Goelz, J Goyal, M Green - Journal of Interferon & Cytokine Research, 2002 - dx.doi.org
... The observed increases in Stat2 levels may also have an effect on alterations of ...
un- like the Jurkat cells), the turnover of MxA protein was rela- tively rapid ...
Cited by 10 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Interferon Regulatory Factor 4 Contributes to Transformation of v-Rel-Expressing Fibroblasts - Full text - MIT Libraries
R Hrdličkova, J Nehyba, HR Bose Jr - Mol Cell Biol, 2001 - pubmedcentral.nih.gov
... during vertebrate evolution, and essentially the same five transcription
factors—RelA, RelB, c ... to DNA binding by a complex composed of STAT1, STAT2, and IRF- ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Interferon alpha/beta Promotes Cell Survival by Activating Nuclear Factor kappa B through … - Full text - MIT Libraries
CH Yang, A Murti, SR Pfeffer, JG Kim, DB Donner, … - J Biol Chem, 2001 - jbc.org
... tyrosine phosphorylation of STAT proteins (4-6). IFN-activated STATs (STAT1, STAT2,
and STAT3 ... B family of polypeptides (p50, p52, c-Rel, v-Rel, RelA (p65), and ...
Cited by 46 - Web Search - jbc.org - ncbi.nlm.nih.gov

Stat 1 depends on transcriptional synergy with Sp 1. - Full text - MIT Libraries
DC Look, MR Pelletier, RM Tidwell, WT Roswit, MJ … - J Biol Chem, 1995 - jbc.org
... domains of several other transcription factors (including p65/RelA, Fos, or ... Additional
immunoblotting indicated that hTBECs also contain Stat2, -3, -5, and -6 ...
Cited by 117 - Web Search - jbc.org - ncbi.nlm.nih.gov

NF-kappa B-dependent Induction of Cyclin D 1 by Retinoblastoma Protein(pRB) Family Proteins and … - Full text - MIT Libraries
T Takebayashi, H Higashi, H Sudo, H Ozawa, E … - J Biol Chem, 2003 - jbc.org
... B2, -229 STAT2, -95 SP1, -23 NF- B3, -229 STAT2/CREB mut, and -229 STAT2/NF- B3 ...
3C). As reported (46-48), ectopic expression of the p65 (RelA) subunit of NF- B ...
Cited by 3 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Interferon modulates the messenger RNA of G 1-controlling genes to suppress the G 1-to-S transition …
H Yamada, K Ochi, S Nakada, S Takahara, T Nemoto, … - Molecular and Cellular Biochemistry, 1995 - springerlink.com
... In addition, the association of Statl-Stat2 complex with other transcription factors
plays a key role in cell transformation or apoptosis ... B) Rela- tive amounts ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

HCDM/GSDS-EXPERIENCES WITH CASE FOR TELECOM SYSTEMS
H Fastenbauer, H Saria - Software Engineering for Telecommunication Switching Systems …, 1989 - ieeexplore.ieee.org
... shows that pow- erful languages like SQL together with rela- tional databases ... GSDS
(Graphical Software Design Tool) idle STAT1) request STAT2) 1acknowIedge I ...
Web Search - ieeexplore.ieee.org

Constitutive nuclear factor kB activity is required to elicit interferon-g-induced expression of … - Full text - MIT Libraries
M HIROI, Y OHMORI - Biochem. J, 2003 - biochemj.org
... 9)/p48, STAT1 (signal transducer and activator of transcription) 1 and STAT2
[17,19 ... Antibodies against STAT1 (E23), NF-kB p50 (NLS), RelA (C-20), RNA polymerase ...
Cached - Web Search - biochemj.org

Interferon Regulatory Factor 4 Contributes to Transformation of v-Rel-Expressing Fibroblasts
HR Bose Jr - mcb.asm.org
... during vertebrate evolution, and essentially the same five transcription factors
RelA, RelB, c-Rel ... to DNA binding by a complex composed of STAT1, STAT2, and IRF ...
Web Search

Interferon/Promotes Cell Survival by Activating Nuclear Factor B through Phosphatidylinositol 3- … - Full text - MIT Libraries
CH Yang, A Murti, SR Pfeffer, JG Kim, DB Donner, … - J Biol Chem, 2001 - intl.jbc.org
... phos- phorylation of STAT proteins (4–6). IFN-activated STATs (STAT1, STAT2, and
STAT3 ... NF- B family of polypeptides (p50, p52, c-Rel, v-Rel, RelA (p65), and ...
Cited by 4 - Web Search - cmdr.ubc.ca - cmdr.ubc.ca

Triggering the Interferon Response: The Role of IRF-3 Transcription Factor
J Hiscott, P Pitha, P Genin, H Nguyen, C … - Journal of Interferon & Cytokine Research, 1999 - dx.doi.org
... p48, which in IFN-treated cells interacts with phosphorylatedStat1 and Stat2
transcriptionfactors, form ... Expression of NF-k B RelA(p65), IRF-1, and IRF-3 alone ...
Cited by 51 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Constitutive Nuclear Factor-B Activity is Required to Elicit Interferon Gamma-Induced Expression of …
M HIROI, Y OHMORI - biochemj.org
... and activator of transcription 1 (STAT1), STAT2, and interferon regulatory
factor–9 (IRF-9 ... κB p50 (NLS), RelA (C-20), RNA polymerase II (N-20), IκBα (C-21 ...
View as HTML - Web Search

Biochemical Assessment of Intracellular Signal Transduction Pathways in Eosinophils: Implications …
C Wong, W Ip, C Kei Lam - Critical Reviews in Clinical Laboratory Sciences, 2004 - dx.doi.org
... JAK3, and Tyk2) and at least nine different STATs (STAT1α, STAT1β, STAT2, STAT3,
STAT3β ... as a dimer composed of two Rel family proteins: p50 and RelA (p65). ...
Cited by 4 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

VIRUSES AND THE TYPE I INTERFERON ANTIVIRAL SYSTEM: INDUCTION AND EVASION
CF BASLER, A GARC& x 000 CD A-SASTRE - International Reviews Of Immunology, 2002 - dx.doi.org
... The STAT1:STAT2:IRF-9 complex, known as ISGF-3, binds to the ISRE elements ... The rela-
tively small difference in susceptibility of wild-type and PKR -=- mice to ...
Cited by 13 - Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Constitutive nuclear factor kappaB activity is required to elicit interferon-gamma-induced … - Full text - MIT Libraries
M Hiroi, Y Ohmori - Biochem. J, 2003 - biochemj.org
... 9)/p48, STAT1 (signal transducer and activator of transcription) 1 and STAT2
[17,19 ... Antibodies againstSTAT1(E23),NF-κBp50(NLS),RelA(C-20),RNApoly- merase II ( ...
Cited by 2 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Induction of interferons and interferon-induced genes
A Background - Biotherapy, 1996 - springerlink.com
... in the cytoplasm by tyrosine phosphorylation, the STATla//3 p91/p84 and STAT2 p
113 ... of phos- phorylation on a given STAT factor or different rela- tive orders ...
Web Search

Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription … - Full text - MIT Libraries
F Macian, A Rao - Mol. Cell. Biol, 1999 - mcb.asm.org
... in CD4 + cells is negatively controlled by competitive binding of RelA to the P ... It
has been shown that Stat2 modulates HIV gene expression by competing for the ...
Cited by 33 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Phosphotyrosine Proteomic Study of Interferon Signaling Pathway Using a Combination of … - Full text - MIT Libraries
H Zheng, P Hu, DF Quinn, YK Wang - Mol. Cell. Proteomics, 2005 - mcponline.org
... transduction pathway by tyrosine phosphorylation of JAK1, Tyk2, STAT1, and STAT2
(12). ... data not shown), and they corresponded to proteins of rela- tively high ...
Cited by 1 - Web Search

Interferon-beta activates multiple signaling cascades in primary human microglia - Full text - MIT Libraries
MO Kim, Q Si, JN Zhou, RG Pestell, CF Brosnan, J … - Journal of Neurochemistry, 2002 - blackwell-synergy.com
... h) showed that the ISG-15 ISRE complex contained IRF-1, but not Stat1, Stat2, IRF3
or ... of the Rel/NF- B family of polypeptides [p50, p52, c-Rel, RelA (p65), and ...
Cited by 20 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Locus-Specific Constitutive and Cytokine-Induced HLA Class I Gene Expression - Full text - MIT Libraries
DR Johnson - The Journal of Immunology, 2003 - jimmunol.org
... the HLA-B7 promoter, nor did any modulate the activity of CIITA or RelA/NF- B1 ... mutant
cells: the ISGF3 mutant U2, the STAT1 mutant U3, and the STAT2 mutant U6 ...
Cited by 4 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Role of the JAK/STAT Signal Transduction Pathway in the Regulation of Gene Expression in CNS
P Dell’Albani, R Santangelo, L Torrisi, VG … - Neurochemical Research, 2003 - kluweronline.com
... STATs 1, 3, 4, 5a, and 5b, possess rela- tively short carboxy-terminal regions of
about 40–50 amino acids, while STAT2 and STAT6 have longer carboxy-terminal ...
Cited by 3 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries