NF-kappa B/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic … - Full text - MIT Libraries
CE Donovan, DA Mark, HZ He, HC Liou, L Kobzik, Y … - J Immunol, 1999 - jimmunol.org
... Specifically, we tested whether loss of c-Rel would lead to inhibition of allergic
disease, including AHR. ... Allergen-treated c-Rel -/- mice did not develop AHR. ...
Cited by 41 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer - Full text - MIT Libraries
MA Sovak, RE Bellas, DW Kim, GJ Zanieski, AE … - J Clin Invest, 1997 - jci.org
... AhR, Aromatic hydrocarbon receptor; BSAP; B cell specific activator protein; CAT ...
a)anthracene; GST, glutathione-S-transferase; I B- , NF- B/ Rel inhibitor- ; NF ...
Cited by 240 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

The RelA NF-kB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc … - Full text - MIT Libraries
DW Kim, L Gazourian, SA Quadri, R Romieu-Mourez, … - Oncogene, 2000 - nature.com
... RelA and AhR cooperate to activate the c-myc promoter in non-malignant MCF-10F cells
To determine whether AhR and NF-kB/Rel can function cooperatively, we ...
Cited by 27 - Web Search - ncbi.nlm.nih.gov

[CITATION] The aryl hydrocarbon receptor/transcription factor (AhR) and the Rel A nuclear factor-κB subunit …
DW Kim, L Gazourian, SA Quadri, DH Sherr, GE … - Submitted for publication, 2000
Cited by 1 - Web Search

… Tumor Necrosis Factor-alpha and Anti-CD40-Induced Activation of NF-kappa B/Rel in Dendritic Cells: … - Full text - MIT Libraries
CE Ruby, M Leid, NI Kerkvliet - Mol. Pharmacol, 2002 - intl-molpharm.aspetjournals.org
... Thus, RelA seems to be the dominant NF- B/Rel protein to interact with the AhR. ...
7. Overexpression of AhR blocks Rel/p50 heterodimer binding. ...
Cited by 4 - Web Search - molpharm.aspetjournals.org - ncbi.nlm.nih.gov

Interactions at a dioxin responsive element(DRE) and an overlapping Kappa B site within the hs 4 …
CEW Sulentic, JS Kang, YJ Na, NE Kaminski - Toxicology, 2004 - ncbi.nlm.nih.gov
... We have previously demonstrated TCDD-inducible binding of both the AhR nuclear complex
and NF-kappaB/Rel proteins to the DRE and kappaB motifs, respectively ...
Cited by 1 - Web Search - csa.com - Get it from MIT Libraries

Expression of the aryl hydrocarbon receptor/transcription factor (AhR) and AhR-regulated CYP1 gene … - Full text - MIT Libraries
AF Trombino, RI Near, RA Matulka, S Yang, LJ Hafer … - Breast Cancer Res. Treat, 2000 - springerlink.com
... Interestingly, dimeriza- tion of the AhR with NF-κB/Rel [44, 45] and tran- scriptional
activation of the c-myc promoter by an AhR/Rel-A complex in human ...
Cited by 18 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov

Author (s)
CEW Sulentic, JS Kang, YJ Na, NE Kaminski, VP … - aapspharmaceutica.com
... We have previously demonstrated TCDD-inducible binding of both the AhR nuclear complex
and NF-@kB/Rel proteins to the DRE and @kB motifs, respectively, as well ...
Cached - Web Search - aapspharmaceutica.com

The RelA NF-kappa B subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c …
NPG Contact - nature.com
... In contrast, cooperation between AhR and RelB or c-Rel subunits of NF- B/Rel in
transactivation of the c-myc gene was not observed in similar transfection ...
Web Search - nature.com

Aryl hydrocarbon receptor(AhR) agonists suppress interleukin-6 expression by bone marrow stromal … - Full text - MIT Libraries
B Jensen, R Leeman, J Schlezinger, D Sherr - Environmental Health: A Global Access Science Source, 2003 - dx.doi.org
... time-PCR indicated a significant inhibition of IL-6 mRNA by AhR ligands within ... in
the LPS-mediated induction of DNA-binding RelA/p50 and c-Rel/p50 heterodimers ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - ehjournal.net - citebase.eprints.org - all 9 versions »

Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity …
K Hilscherova, M Machala, K Kannan, AL Blankenship … - Environ. Sci. Pollut. Res, 2000 - oekomorph-zoologie.uni-hd.de
... Review Articles Cell Bioassays for Detection of Aryl Hydrocarbon (AhR) ... Their effects
can be mediated through receptor-mediated mechanisms (such as AhR ligand ...
Cited by 19 - View as HTML - Web Search - zoo.uni-heidelberg.de - zoo.uni-heidelberg.de

Aryl Hydrocarbon Receptor (AhR) Agonists Suppress Interleukin-6 Expression by Bone Marrow Stromal …
BA Jensen, RJ Leeman, JJ Schlezinger, DH Sherr - biomedcentral.com
... binding RelA/p50 and c-Rel/p50 heterodimers in the presence of DMBA. Conclusions:
Common environmental AhR agonists can suppress an innate ...
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Sequence variation and phylogenetic history of the mouse Ahr gene
RS Thomas, SG Penn, K Holden, CA Bradfield, DR … - Pharmacogenetics, 2002 - edge.oncology.wisc.edu
... The PAS domain of the Ahr is contained within exons 3±9 with the ligand-binding
region encoded by exons 7 and 8 (Fig. ... brea kdown rel ative to the reference ...
Cited by 10 - View as HTML - Web Search - genome.oncology.wisc.edu - mcardle.oncology.wisc.edu - ncbi.nlm.nih.gov - Get it from MIT Libraries

The arylhydrocarbon receptor(AhR), but not the AhR-nuclear translocator(ARNT), is increased in … - Full text - MIT Libraries
M Mehrabi, G Steiner, C Dellinger, A Kofler, K … - Virchows Archiv, 2002 - springerlink.com
... patterns, we demonstrated an in- crease in the number of AhR-positive myocardial
cells in hearts from patients with ischemic and dilative CMP rel- ative to ...
Web Search - ncbi.nlm.nih.gov

Full record
A Brenda, L Rebecca, S Jennifer, S David - doaj.org
... time-PCR indicated a significant inhibition of IL-6 mRNA by AhR ligands within ... in
the LPS-mediated induction of DNA-binding RelA/p50 and c-Rel/p50 heterodimers ...
Cached - Web Search - doaj.org

A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol - Full text - MIT Libraries
J Gusman, H Malonne, G Atassi - Carcinogenesis, 2001 - carcin.oupjournals.org
... Abbreviations: ACF, aberrant crypt foci; AhR, aryl hydrocarbon receptor; AP-1,
activator protein ... of NF B. The latter is a member of the Rel transcription factor ...
Cited by 46 - Web Search - carcin.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Mouse Models for the Genetic Dissection of Atopy - Full text - MIT Libraries
A Heinzmann, A Daser, F Alert - International Archives of Allergy and Immunology, 2002 - content.karger.com
... Specifically, c-Rel has been associated with AHR, PI, AE and total serum IgE levels
[10]. ... [70] Th2 cytokines Decrease Rel–/– AHR Protection Donovan et al. ...
Cited by 4 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

A low volume method for the analysis of dioxins and dioxin-like compounds in serum and whole blood …
B Brouwer, E Sonneveld, S Botschuijver, H … - ORGANOHALOGEN COMPOUNDS, 2004 - dioxin2004.abstract-management.de
... rat hepatoma H4IIE cell line stably transfected with an AhR-controlled luciferase ...
S r (rel) = repeatability (relative) S R (rel) = reproducibility (relative) n ...
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Putative link between transcriptional regulation of IgM expression by 2, 3, 7, 8-tetrachlorodibenzo- … - Full text - MIT Libraries
CE Sulentic, MP Holsapple, NE Kaminski - J. Pharmacol. Exp. Ther, 2000 - jpet.aspetjournals.org
... of DNA binding by NF- B/Rel proteins after TCDD treatment in the AhR-deficient
BCL-1 cells suggests an AhR-independent activation of p65, RelB, and c-Rel. ...
Cited by 22 - Web Search - jpet.aspetjournals.org - ncbi.nlm.nih.gov

2-Tert-butylmercapto-5-(isoamyl-
VR REL - Khimiya Geterotsiklicheskikh Soedinenii, 1965 - springerlink.com
... 21 22 23 24 Compound Bp, *C ?EGA/ DK + alkali 150" PEGA/DK PEGA! Sili- 1:§ cone
on ,a i NaC1 leO I 170 } ,80 VR REL ... (AHr = [l--(Tr)l ] 0.38 (Any)= Ll--(Tr)21, ...
Web Search

Validation of extraction, clean-up and DR CALUX® bioanalysis. Part I: feedingstuff
H Besselink, A Jonas, M Pijnappels, A Swinkels, B … - ORGANOHALOGEN COMPOUNDS, 2004 - dioxin2004.abstract-management.de
... rat hepatoma H4IIE cell line stably transfected with an AhR-controlled luciferase ...
S r (rel) = repeatability (relative) S R (rel) = reproducibility (relative) n ...
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NICKEL—HYDROGEN BATTERY CELLS John J. Smithrick NASA Lewis Reserh Center Cleveland, Ohio 44135 and
EOFLEOC ON, AAD IPV - ieeexplore.ieee.org
... For the other two cells the pressure increased rel- atively rapidly up to ... CONCLUDING
REMARKS Validation testing of NASA Lewis 125 Ahr advanced design IPV nickel ...
Web Search

Untersuchung iiber die Homopolymerisation des Triallylcyanurats
VHJ Booss, KR HAUSCHILDT - doi.wiley.com
... der Reaktionsenthalpie AHR des TAC. AHM GPhalt TAIC I AHR ' w (cam 4 energie Umsatz
rel. Doppelbindungen bei Absorption an Umwandlungs- rel. Absorption bei ...
Web Search

REDOX REGULATION OF c-Ha-ras AND OSTEOPONTIN SIGNALING IN VASCULAR SMOOTH MUSCLE CELLS: Implications … - Full text - MIT Libraries
KS Ramos - Annual Review of Pharmacology and Toxicology, 1999 - pharmtox.annualreviews.org
... exploited in our efforts to characterize the involvement of the AhR in atherogenesis. ...
NFκB is a member of the Rel protein family consisting of two distinct ...
Cited by 22 - Web Search - ncbi.nlm.nih.gov

Environmental Health: A Global Access Science Source - Full text - MIT Libraries
BA Jensen, RJ Leeman, JJ Schlezinger, DH Sherr - Environmental Health: A Global Access Science Source, 2003 - bmc.ub.uni-potsdam.de
... in the LPS-mediated induction of DNA-binding RelA/p50 and c-Rel/p50 heterodimers
in the presence of DMBA. Conclusions: Common environmental AhR agonists can ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de

The hsp90 Co-chaperone XAP2 Alters Importin Recognition of the Bipartite Nuclear Localization Signal …
JR Petrulis, A Kusnadi, P Ramadoss, B Hollingshead … - cas.psu.edu
... In contrast, AhR complexed with a rel- atively large amount of XAP2 exhibited
3-fold less specific binding of importin to the AhR. Whether importin is ...
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Validation of extraction, clean-up and DR CALUX® bioanalysis. Part II: foodstuff
H Besselink, A Jonas, M Pijnappels, A Swinkels, B … - ORGANOHALOGEN COMPOUNDS, 2004 - dioxin2004.abstract-management.de
... rat hepatoma H4IIE cell line stably transfected with an AhR-controlled luciferase ...
S r (rel) = repeatability (relative) S R (rel) = reproducibility (relative) n ...
View as HTML - Web Search

Distribution of mRNAs Encoding the Arylhydrocarbon Receptor, Arylhydrocarbon Receptor Nuclear … - Full text - MIT Libraries
CD CARPENTER, LS LUBBERS, MD Mc ABEE - THE JOURNAL OF COMPARATIVE NEUROLOGY, 2000 - doi.wiley.com
... Rel- ative levels of AhR, ARNT, and ARNT2 mRNAs were determined by placing the
x-ray films on a light box and measuring the optical densities of ...
Web Search - doi.wiley.com

Structure of tetrabutylammonium bis [benzene-1, 2-dithiolato (2-)] oxorhenate (V)
R Huebener, U Abram - Structure, 1993 - scripts.iucr.org
... LS shift to esd (Ahr) 0.02 Max ... Rel--OI 1.70 (2) Rel--Sl Rel--S2 2.311 (6) ReI--S3
ReI--S4 2.307 (6) SIICI 1 $2-----C 12 1.72 (2) $3--C21 $4IC22 1.77 (2) OI--Rel ...
Web Search - scripts.iucr.org - Get it from MIT Libraries

Acta Crystallographica Section C
R Huebener, U Abram, J Straehle - Crystal Structure Communications - dx.doi.org
... LS shift to esd (Ahr) 0.02 Max ... Rel--OI 1.70 (2) Rel--Sl Rel--S2 2.311 (6) ReI--S3
ReI--S4 2.307 (6) SIICI 1 $2-----C 12 1.72 (2) $3--C21 $4IC22 1.77 (2) OI--Rel ...
Web Search - dx.doi.org

Dioxin-induced Immortalization of Normal Human Keratinocytes and Silencing of p 53 and p 16 INK 4 a - Full text - MIT Libraries
SS Ray, HI Swanson - J Biol Chem, 2004 - jbc.org
... (AHR), a ligand activated transcription factor belonging to the bHLH-PAS family, ...
absolutely requires the AHR and is accompanied by promoter methylation. ...
Cited by 3 - Web Search - dx.doi.org - ijmm.org - ijp-online.com - all 8 versions »

2Bi. R/L Systems Overview: What Do They Do? 2Bii. The R/L Web and Xenobiotic Modulations
SC Rowat - rowatworks.com
... These results appear to have considerable rel- evance for study of presumed CI and
CR condi ... others (or 8, including IL-1); and so on, down to the AhR which was ...
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2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin, an Exogenous Modulator of the 3'{alpha} Immunoglobulin Heavy … - Full text - MIT Libraries
CEW Sulentic, W Zhang, YJ Na, NE Kaminski - J. Pharmacol. Exp. Ther, 2004 - jpet.aspetjournals.org
... However, the AhR and Rel proteins do not seem to dimerize as evidenced by EMSA-Western
analysis in which the AhR/ARNT-bound DNA migrated differently from NF- B ...
Cited by 1 - Web Search - intl-jpet.aspetjournals.org - intl-jpet.aspetjournals.org - ncbi.nlm.nih.gov

Alterations in lung collectins in an adaptive allergic immune response - Full text - MIT Libraries
KJ Haley, A Ciota, JP Contreras, MR Boothby, DL … - Am J Physiol Lung Cell Mol Physiol, 2002 - ajplung.physiology.org
... are upregulated after allergen sensitization concomitant with the kinetics of
allergen-induced AHR. ... and SP-D expression is preserved in the c-Rel mice despite ...
Cited by 9 - Web Search - ajplung.physiology.org - ncbi.nlm.nih.gov

Effects of fluticasone plus salmeterol versus twice the dose of fluticasone in asthmatic patients - Full text - MIT Libraries
GP Currie, CE Bates, DK Lee, CM Jackson, BJ … - Eur J Clin Pharmacol, 2003 - springerlink.com
... demonstrated no fur- ther decrease in exhaled NO or AHR to AMP ... inhaled corticosteroid
therapy with fluticasone alone conferred superiority rel- ative to half ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

A Dynamic Role for the Ah Receptor in Cell Signaling?
DB Carlson, GH Perdew - doi.wiley.com
... Di- rect interactions between AhR and Rel A (a NF B sub- unit) induce transactivation
of c-myc in breast cancer cell lines MCF-10F and Hs578T [39]. ...
Web Search - cas.psu.edu

Annual Review of Pharmacology and Toxicology - Full text - MIT Libraries
KS Ramos - Annual Review of Pharmacology and Toxicology, 1999 - pharmtox.annualreviews.org
... being exploited in our efforts to characterize the involvement of the AhR in
atherogenesis ... NF B is a member of the Rel protein family consisting of two distinct ...
Web Search - pharmtox.annualreviews.org

Application of kernel method to reveal subtypes of TF binding motifs. Causal analysis of gene …
A Kel, Y Tikunov, N Voss, J Borlak, E Wingender - biobase.de
... combinations of different types of TF binding sites including two AhR pattern subtypes
that ... We used TRANSFAC® Professional rel.6.4 and TRANSCompel® rel.6.4. ...
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ANALYSIS OF THE TUMOR-PROMOTING POTENCY OF 2, 4, 4'-TRICHLOROBIPHENYL AND 2, 2', 4, 5, 5'- …
S Kunz, HJ Schmitz, A Buchmann, M Schwarz, B … - ORGANOHALOGEN COMPOUNDS, 2004 - dioxin2004.abstract-management.de
... P450 (CYP) 1A1 3 . On the other hand, ‘non-dioxin-like’ PCB congeners have a lower
or no binding affinity to the AhR, but exhibit a ... of animals rel. ...
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0568-5230/89/3808-1645512.50 9 Plenum Publishing Corporation 1645
RTO ACETYLENE - springerlink.com
... of the acidities of benzene and acetylene follows from the value of AHr(MNDO) for
the ... The complex of the ethynide ion with acetylene is rel- atively stable, and ...
Web Search

Involvement of tachykinin NK 1 and NK 2 receptors in substance P-induced microvascular leakage … - Full text - MIT Libraries
E Boichot, K Biyah, N Germain, X Emonds-Alt, V … - European Respiratory Journal, 1996 - erj.ersjournals.com
... of guinea-pigs to an aerosol of capsaicin or substance P, substances that rel- ease
endogenous sensory neuropeptides, such as SP, elici- ted AHR to exogenous ...
Cited by 11 - Web Search - erj.ersjournals.com - erj.ersjournals.com - ncbi.nlm.nih.gov

Costimulatory molecule OX40L is critical for both Th1 and Th2 responses in allergic inflammation - Full text - MIT Libraries
RS Arestides, H He, RM Westlake, AI Chen, AH … - Eur. J. Immunol, 2002 - doi.wiley.com
... Twenty-four hours following the final aerosol challenge, AHR was assessed using
whole-body ... GT, Perkins, DL and Finn, PW, NF- kappa B/Rel transcription factors ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov

Seasonal Difference in the Occurrence of Exercise-Induced Bronchospasm in Asthmatics: Dependence on … - Full text - MIT Libraries
YIKIS Choi - Respiration, 2002 - content.karger.com
... 3 subjects without AHR to methacholine or exercise had shown AHR to a ... 2. Comparisons
of temperature ( a ), rel- ative humidity ( b ), percentages of cases with ...
Cited by 6 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Structural specificity in the lethal and mutagenic activity of furocoumarins in yeast cells
D Averbeck, P Chandra, RK Biswas - Radiation and Environmental Biophysics, 1975 - springerlink.com
... The ratlos of D 0 (AHR) over D 0 (IMM) after both treatments are about the same. ...
5 b. Data obtained after ultraviolet light at 254 nm are included (Rel. [22]) ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Toxicology and Risk Assessment of POPs
S Safe - Handbook of Environmental Chemistry, O. Hutzinger, Ed. …, 2003 - springerlink.com
... the sum of the concentrations of individual components times their potency (TEF)
rel- ative to TCDD.A number of studies also demonstrate that AhR-inactive POPs ...
Cited by 1 - Web Search

Expression of angiogenic factors including VEGFs and the effects of hypoxia and thalidomide on human … - Full text - MIT Libraries
K Yata, T Otsuki, J Kurebayashi, M Uno, T Fujii, Y … - Int J Oncol, 2003 - virology.med.uoc.gr
... receptor nuclear translocator-like (ARNTL) gene, aryl hydrocarbon receptor (AHR),
and p53 ... The correlation to alterations of REL in individual genes (REL of ...
Cited by 4 - View as HTML - Web Search - 147.52.72.117 - ncbi.nlm.nih.gov

I) iagnostische Beurteilung eines familiiren spastischen Syndroms
H HANs - springerlink.com
... Globulinfraktion), T-Frak- tion: 7,3 rel-o, y- Globuline: 13,0 rel-o, Gesamteiwei ...
Le- bensj ahr des Vaters, der zum Zeitpnnkt der Untersuehung 2 Jahre alten 3I. ...
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Administration of pentoxifylline during allergen sensitization dissociates pulmonary allergic … - Full text - MIT Libraries
CM Fleming, H He, A Ciota, D Perkins, PW Finn - J Immunol, 2001 - jimmunol.org
... B family member c-Rel (c-Rel knockout mice) prevents the development of allergic
pulmonary inflammation and AHR following allergen sensitization and challenge ( ...
Cited by 8 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Exoestrogens: Mechanisms of action and strategies for identification and assessment
BE Gillesby, TR Zacharewski - Environmental Toxicology and Chemistry, 1998 - entc.allenpress.com
... may partially explain some of the antiestrogenic activities observed with AhR ligands. ...
domains (domains C and D) interact directly with the Rel homology domain ...
Cited by 58 - Web Search - etc.allenpress.com - entc.allenpress.com - csa.com - all 5 versions »

Highly Chlorinated PCBs Inhibit the Human Xenobiotic Response Mediated by the Steroid and Xenobiotic … - Full text - MIT Libraries
MM Tabb, V Kholodovych, F Gruen, C Zhou, WJ Welsh, … - Environmental Health Perspectives, 2004 - devcell.bio.uci.edu
... F 5-CTTCATCCAATG- GACTGCATAAAT-3), (R 5-TCCCAAG- TATAACACTCTACACAGACAA-3); AhR:
(F 5 ... by the comparative cycle threshold method for rel- ative quantitation of ...
Cited by 8 - View as HTML - Web Search - earthscape.org - ehp.niehs.nih.gov - unc.edu - all 12 versions »