A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway … - Full text - MIT Libraries
J Das, CH Chen, L Yang, L Cohn, P Ray, A Ray - Nat Immunol, 2001 - nature.com
... that, although other NF- B and Rel proteins can substitute for activation of Il2,
Gata3 induction cannot be replaced by other members of this family. ...
Cited by 108 - Web Search - nature.com - ncbi.nlm.nih.gov

c-Rel delivers a one-two punch in Th1 cell differentiation - Full text - MIT Libraries
SY Pai, IC Ho - J Clin Invest, 2002 - jci.org
... Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell ...
A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation - Full text - MIT Libraries
BA Hilliard, N Mason, L Xu, J Sun, SE Lamhamedi- … - J. Clin. Invest, 2002 - jci.org
... These include STAT-4, STAT-6, Gata3, T-bet, c-Maf, NF-AT, AP-1, and NF- B1 (34-36).
Results reported here indicate that c-Rel is another transcription factor ...
Cited by 22 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Distinctions between c-Rel and other NF-kB proteins in immunity and disease
HC Liou, CY Hsia - doi.wiley.com
... Target genes (cell type specific) Cyclin D1, Jagged 1, GATA3 IAPs, c-FLIP, TRAFs,
bcl-2, Fas ... since the IkBa transgene can inhibit most NF-kB/Rel family members. ...
Web Search

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... Family: NFKB1, NFKB2, NFKBIA, NFKBIB, NFKBIL1, NFKBIL2, NFRKB, REL, RELA, RELB. ... ETS2,
FKBP1B, FLJ14639 (NIP45), FOS, FOSL1, FOXO1A, FOXO3A, GATA3, GATA4, GRLF1 ...
View as HTML - Web Search - eurogentec.be

Specificity of SN50 for NF-{kappa} B - Full text - MIT Libraries
M Boothby, A Ray - Nat Immunol, 2001 - nature.com
... STAT6, on the other hand, regulates GATA3, which, along with NFATc, plays a key ... obtained
with other approaches to the inhibition of NF-κB (Rel) family dimers ...
Cited by 7 - Web Search - nature.com - ncbi.nlm.nih.gov

Response to'Specificity of SN50 for NF-kappa B?' - Full text - MIT Libraries
A Ray - Nature Immunology, 2001 - nature.com
... in which the functions of multiple Rel family members or of other Rel proteins are ...
Mark Boothby and the A critical role for NF- kappaB in Gata3 expression and ...
Web Search - nature.com

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis - Full text - MIT Libraries
E Bettelli, B Sullivan, SJ Szabo, RA Sobel, LH … - J. Exp. Med, 2004 - jem.org
... factors T-bet, signal transducer and activator of transcription (STAT)1, STAT4,
and c-Rel are essential for the development of Th1 cells while GATA3, c-maf ...
Cited by 4 - Web Search - dx.doi.org - jem.org - ncbi.nlm.nih.gov

Role of NFAT proteins in IL13 gene transcription in mast cells - Full text - MIT Libraries
S Monticelli, DC Solymar, A Rao - J. Biol. Chem, 2004 - jbc.org
... 50) showed that transgenic expression of GATA2 and GATA3 under the ... fingers of GATA
proteins interact with the C-terminal domain of the NFAT Rel homology region ...
Cited by 2 - Web Search - dx.doi.org - ijmm.org - ncbi.nlm.nih.gov - all 5 versions »

Decision making in the immune system: The lineage decisions of helper T cells - Full text - MIT Libraries
KM Murphy, SL Reiner - Nature Reviews Immunology, 2002 - nature.com
... Immunity 12, 27-37 (2000). This study showed that GATA3 might act independently
of STAT6 and that GATA3 induces chromatin remodelling of the IL-4 locus. ...
Cited by 8 - Web Search

Nuclear Factor Kappa B Activation in Human Cord Blood Mononuclear Cells - Full text - MIT Libraries
CH SCHROETER, B SCHAUB, DR GOLD, PJ CONTRERAS, O … - Pediatric Research, 2004 - pedresearch.org
... extracts were preincubated with polyclonal antibodies against p65, p50, and c-rel
(Geneka, Montreal, Canada), or MAb against STAT4 and GATA3 (Santa Cruz ...
Web Search - intl.pedresearch.org - pedresearch.org - ncbi.nlm.nih.gov - all 5 versions »

Identification of nucleotide sequences that regulate transcription of the MCF13 murine leukemia … - Full text - MIT Libraries
FK Yoshimura, M Cankovic, R Smeltz, S Ibrahim - J. Virol, 1997 - jvi.asm.org
... 1993. NF- B and Rel: partici- pants in a multiform transcriptional regulatory system. ...
The human enhancer-binding protein Gata3 binds to several T-cell receptor ...
Cited by 8 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Large-scale comparative sequence analysis of the human and murine Bruton’s tyrosine kinase loci … - Full text - MIT Libraries
JC Oeltjen, TM Malley, DM Muzny, W Miller, RA … - Genome Res, 1997 - genome.org
... These include Ap1-b, CCAAT/enhancer-binding protein (C/EBP ), c-ETS-1, c-Rel, GATA1,
GATA2, GATA3, necrosis factor-E2 (NF-E2), and, NF- B (for review, see ...
Cited by 94 - Web Search - genome.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Mouse Models for the Genetic Dissection of Atopy - Full text - MIT Libraries
A Heinzmann, A Daser, F Alert - International Archives of Allergy and Immunology, 2002 - content.karger.com
... PI Absence Total IgE Decrease Th2 cytokines Absence Th1 cytokines Increase Gata3–/–
AE Decrease Zhang ... [70] Th2 cytokines Decrease Rel–/– AHR Protection ...
Cited by 4 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Regulation of IL 4 gene expression by T cells and therapeutic perspectives - Full text - MIT Libraries
M Li-Weber, PH Krammer - Nature Reviews Immunology, 2003 - nature.com
1. Jankovic, D., Sher, A. & Yap, G. T H 1/T H 2 effector choice in parasitic infection:
decision making by committee. Curr. Opin. Immunol. 13, 403-409 (2001). ...
Cited by 11 - Web Search - nature.com - ncbi.nlm.nih.gov

Deborah L. Weiss Regulation of IL-4 production in - Full text - MIT Libraries
MA Brown - Immunological Reviews, 2001 - ingentaconnect.com
... coding a portion of the NF-AT1 rel homology domain ... Th2-associated transcription factors
c-maf, STAT6 and GATA3 are not involved in IL-4 expression by mast cells ...
Web Search - cbr.med.harvard.edu

Amino Terminus of the Yeast GAL4 Gene Product is Sufficient for Nuclear Localization - Full text - MIT Libraries
PA Silver, LP Keegan, M Ptashne - J. Biol. Chem, 2004 - pnas.org
... J. Sampson, AJ Williams, and RV Thakker Characterization of GATA3 Mutations in ... members
only encodes a Drosophila nucleoporin required for Rel protein import ...
Cited by 79 - Web Search - pubmedcentral.nih.gov - biologicalprocedures.com - ncbi.nlm.nih.gov

Associations between gene expressions in breast cancer and patient survival - Full text - MIT Libraries
TK Jenssen, WP Kuo, T Stokke, E Hovig - Hum Genet, 2002 - springerlink.com
... There were two copies of GATA3, corresponding to two distinct spots on the arrays. ...
ber of groups b GRO1 W42723 4.4 E-16 Low 2 GATA3 R31441 3.8 E–14 High 3 ...
Cited by 13 - Web Search - pubgeneserver.uio.no - pubgene.com - idi.ntnu.no - all 6 versions »

Presentation at the National Asthma Campaign International Congress, June 1999 Controlling the … - Full text - MIT Libraries
P Lavender, D Cousins, P Smith, T Lee - Clinical & Experimental Allergy, 2000 - dx.doi.org
... It is suggested that this element contains no consensus binding site for GATA3,
c-Maf ... the kappa light chain enhancer [ 68] and is a member of the Rel family. ...
Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov

GEArray S Series Mouse Autoimmune and Inflammatory Response Gene Array: AR-SAMM-602.3
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.com
... Egr1, Egr2, Egr3, Elk1, Elk3, Fkbp1b, Fos, Fosb, Fosl1, Fosl2, Gata3, Gata4, Icos ...
Nfkb1, Nfkb2, Nfkbia, Nfkbib, Nfkbie, Nfkbil1, P300-ESTs, Raf1, Rel, Rela, Relb ...
View as HTML - Web Search - eurogentec.be

GEArray S Series Human Autoimmune and Inflammatory Response Gene Array: AR-SAHS-602
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.be
... EP300, FKBP1B, FLJ14639 (NIP45), FOS, FOSL1, FOSL2, FOXP3, GATA3, GATA4, GRLF1 ... NFKB2,
NFKBIA, NFKBIB, NFKBIE, NFKBIL1, NFKBIL2, NFRKB, RAF1, REL, RELA, RELB ...
View as HTML - Web Search - eurogentec.com

Regulation of the GATA 3 promoter by human T-cell lymphotropic virus type I Tax protein - Full text - MIT Libraries
SCO Gilli, TSI Salles, STO Saad - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... CRE-binding protein), IkB (an inhibitor of NF- kB/Rel transcription factors ... the
interaction between the specific T-cell tran- scription factor, GATA3, and Tax. ...
Web Search - ncbi.nlm.nih.gov

Impaired NF-kappaB Activation in T Cells Permits Tolerance to Primary Heart Allografts and to … - Full text - MIT Libraries
P Zhou, KW Hwang, DA Palucki, Z Guo, M Boothby, KA … - American Journal of Transplantation, 2003 - blackwell-synergy.com
... T cells from c-Rel-deficient mice have a defect in IL-2 production, IL-2R ... a defect
in Th2 differentiation due to an inability to up-regulate GATA3 (3). Mice ...
Cited by 3 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo - Full text - MIT Libraries
S Agarwal, O Avni, A Rao - Immunity, 2000 - cbr.med.harvard.edu
... The antigen-induced transcription factor NFAT and GATA3 in vivo but is not perceptibly
influenced by the ... The transcription factors cMaf (Maf) and GATA3 show ...
Cited by 100 - View as HTML - Web Search - ncbi.nlm.nih.gov

Partners in transcription: NFAT and AP-1 - Full text - MIT Libraries
F MaciaAn, C LoApez-RodroAguez, A Rao - Oncogene, 2001 - nature.com
... The activity of the IL-5 promoter may also require both NFAT and GATA3. ... structural
variability between di€erent members of the NFAT and Rel families, and may ...
Web Search

Differential requirement for NF-kappa B family members in control of helminth infection and … - Full text - MIT Libraries
D Artis, S Shapira, N Mason, KM Speirs, M … - J Immunol, 2002 - jimmunol.org
... A critical role for NF- B in GATA3 expression and TH2 differentiation in ... Cutting
edge: identification of c-Rel-dependent and -independent pathways of IL-12 ...
Cited by 26 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Technical Advance
PE Tissues - American Journal of Pathology, 2004 - ajp.amjpathol.org
... from the variability inherent in processing surgical tissue specimens, including
rel- ative mass of ... ER1 GATA3 HNF3A HER2 GRB7 ITGA7 LPL RBP4 GRO1 KRT5 KRT17 ...
Web Search - ajp.amjpathol.org - Get it from MIT Libraries

Tumor necrosis factor receptor-associated factor (TRAF) 2 represses the T helper cell type 2 … - Full text - MIT Libraries
R Lieberson, KA Mowen, KD McBride, V Leautaud, X … - J. Exp. Med, 2001 - intl.jem.org
... It may be that GATA3, another Th2-specific factor, can serve this function ... was initially
identified as a factor which interacts with the REL homology domain ...
Cited by 11 - Web Search - jem.org - ncbi.nlm.nih.gov

The Molecular Basis of Th2 Development
M Li-Weber - Current Immunology Reviews, 2005 - ingentaconnect.com
... Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell ...
Cohn L, Ray P, Ray A. A critical role for NF-kappa B in GATA3 expression and ...
Web Search

The role of IRF-4 in B and T cell activation and differentiation
AB Pernis - J. Interferon Cytokine Res, 2002 - dx.doi.org
... 4 upon CD3/CD28 stimulation or BCR engagement is known to require c-Rel, a member ...
Some of these factors, like the recently described T-bet and GATA3, have been ...
Cited by 10 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

New lessons from old pathogens: what parasitic infections have taught us about the role of nuclear … - Full text - MIT Libraries
NJ Mason, D Artis, CA Hunter - Immunological Reviews, 2004 - blackwell-synergy.com
... The nuclear factor- B/reticuloendotheliosis (Rel) family
of transcription factors, Go to: Choose, ...
Web Search - ncbi.nlm.nih.gov

CD 28-mediated co-stimulation: a quantitative support for TCR signalling - Full text - MIT Libraries
O Acuto, F Michel - Nature Reviews Immunology, 2003 - nature.com
... | PubMed | ISI | ChemPort |. 23. Kane, LP, Lin, J. & Weiss, A. It's all Rel-ative:
NF- B and CD28 co-stimulation of T-cell activation. Trends Immunol. ...
Cited by 21 - Web Search - columbia.edu - mail.med.upenn.edu - ncbi.nlm.nih.gov - all 6 versions »

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION - Full text - MIT Libraries
CT Kuo, JM Leiden - Annual Review of Immunology, 1999 - immunol.annualreviews.org
... These include the Ikaros, LKLF, and GATA3 zinc-finger proteins; the Ets, CREB/ATF,
and NF- B/Rel/NFAT transcription factors; the Stat proteins; and HMG box ...
Cited by 125 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells - Full text - MIT Libraries
R Loewe, W Holnthoner, M Groger, M Pillinger, F … - J Immunol, 2002 - jimmunol.org
... Preferential role for NF- B/Rel signaling in the type 1 but not type 2 ... A critical
role for NF- B in GATA3 expression and TH2 differentiation in allergic airway ...
Cited by 9 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

A target selection of somatic hypermutations is regulated similarly between T and B cells upon … - Full text - MIT Libraries
A Kotani, I Okazaki, M Muramatsu, K Kinoshita, NA … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... 3). Freac-7, Gfi-1, and HFH3 have not been extensively investigated, and their
expression in lymphocyte is not reported, whereas GATA3 and c-rel are expressed ...
Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov - all 5 versions »

The lineage decisions of helper T cells - Full text - MIT Libraries
KM Murphy, SL Reiner - Nat. Rev. Immunol, 2002 - nature.com
... mice havea selec- tive defect in IL-4 production 24 .A second,and perhaps further
upstream,T H 2-cell-specific transcription factor, GATA3,was identified ... GATA3 ...
Cited by 170 - Web Search - uiowa.edu - medicine.ucsd.edu - icb.ufmg.br - all 7 versions »

NF-kappa B2 is required for optimal CD40-induced IL-12 production but dispensable for Th1 cell … - Full text - MIT Libraries
K Speirs, J Caamano, MH Goldschmidt, CA Hunter, P … - J. Immunol, 2002 - jimmunol.org
... Preferential role for NF- B/Rel signaling in the type 1 but not type 2 ... A critical
role for NF- B in GATA3 expression and TH2 differentiation in allergic airway ...
Cited by 23 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

NF-k B synergizes with NF-AT and NF-IL6 in activation of the IL-4 gene in T cells
M Li-Weber, M Giaisi, S Baumann, K Palfi, PH … - doi.wiley.com
Page 1. NF- k B synergizes with NF-AT and NF-IL6 in activation of the
IL-4 gene in T cells Min Li-Weber, Marco Giaisi, Sven Baumann ...
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Potential targets of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor for multiple … - Full text - MIT Libraries
N Nath, S Giri, R Prasad, AK Singh, I Singh - J Immunol, 2004 - jimmunol.org
... Lovastatin induced the expression of GATA3 and the phosphorylation of STAT6, whereas
it inhibited tyrosine phosphorylation of Janus kinase 2, tyrosine kinase 2 ...
Cited by 20 - Web Search - jimmunol.org - jautoimdis.com - ncbi.nlm.nih.gov - all 5 versions »

Opposing Roles for RelB and Bcl-3 in Regulation of T-Box Expressed in T Cells, GATA-3, and … - Full text - MIT Libraries
RA Corn, C Hunter, HC Liou, U Siebenlist, MR … - The Journal of Immunology, 2005 - jimmunol.org
... GATA-3, consistent with evidence that Bcl-3 can transactivate a gata3 promoter ... may
be regulated by titrating the stoichiometry of transactivating NF- B/Rel/I B ...
Web Search - jimmunol.org - jimmunol.org - jimmunol.org

Notch Governing Mature T Cell Differentiation - Full text - MIT Libraries
S Tsukumo, K Yasutomo - The Journal of Immunology, 2004 - jimmunol.org
... lacking NF- B1 failed to induce GATA3 expression in CD4 + T cells and were unable
to induce Th2 differentiation (43), whereas mice lacking c-Rel were defective ...
Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

IL-4 Signaling, Gene Transcription Regulation, and the Control of Effector T Cells
JR Sheller, S Goenka, L Stephenson - Immunologic Research, 2001 - neurosci.humanapress.com
... type 2 cytokines is diminished after polyclonal activation of CD4 + T cells derived
from mice deficient in one subunit of the NF-κB/Rel transcription factor ...
Web Search - biomed.humanapress.com - journals.humanapress.com - ingentaconnect.com

Rapid activation of nuclear factor-kappaB in airway epithelium in a murine model of allergic airway … - Full text - MIT Libraries
ME Poynter, CG Irvin, YM Janssen-Heininger - Am J Pathol, 2002 - ajp.amjpathol.org
... Cohn L, Ray P, Ray A: A critical role for NF-kappa B in GATA3 expression and ... L, Wang
Y, De Sanctis GT, Perkins DL, Finn PW: NF-kappa B/Rel transcription factors ...
Cited by 17 - Web Search - ajp.amjpathol.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Origins of immunity: transcription factors and homologues of effector genes of the vertebrate immune … - Full text - MIT Libraries
Z Pancer, JP Rast, EH Davidson - Immunogenetics, 1999 - springerlink.com
... NCAYTA; Gata-YHKMN, CAGCGGCCGCTAY- CAYAARATGA; and 3’ Gata3, CAGTCGACRTANGCRTTR-
CA ... Primer Rel.R4 [5b-TCCTTYTGIACCTTRTCRCA, (Ipinosine), corresponds to the ...
Cited by 27 - Web Search - ncbi.nlm.nih.gov

Roles of interferon-regulatory factors in T-helper-cell differentiation - Full text - MIT Libraries
M Lohoff, TW Mak - Nature Reviews Immunology, 2005 - nature.com
... R., Burnside, J. & Bose, HR A novel interferon regulatory factor (IRF), IRF-10,
has a unique role in immune defense and is induced by the v-Rel oncoprotein. ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov

Modulation of Th1 and Th2 responses for immunotherapy
FJ Dumont - inflammation. - extenza-eps.com
... sequence of events is the induction and main- tained expression of subset-specific
transcription factors, prin- cipally T-bet in Th1 cells and GATA3 in Th2 ...
Cited by 5 - Web Search - ashley-pub.com - dx.doi.org - ingentaconnect.com - all 7 versions »

Regulation of T helper type 2 cell differentiation by murine Schnurri-2
MY Kimura, H Hosokawa, M Yamashita, A Hasegawa, C … - J. Exp. Med. 201: 397, 2005 - jem.org
... Shn-2–deficient developing Th2 cells showed constitutive activation of
nuclear factor B (NF- B) and enhanced GATA3 induction. ...
Cited by 1 - Web Search - jem.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Development and evolution of inner ear sensory epithelia and their innervation - Full text - MIT Libraries
B Fritzsch, KW Beisel, K Jones, I Farinas, A … - Journal of Neurobiology, 2002 - doi.wiley.com
... followed by seg- regation and development of novel, functionally rel- evant
modifications ... genes as revealed with a lac-Z marker inserted into GATA3, BDNF, NeuroD ...
Cited by 16 - Web Search - ucsf.edu - ucsf.edu - ncbi.nlm.nih.gov

L ENTIVIRUS R EPLICATION AND R EGULATION - Full text - MIT Libraries
H Tang, KL Kuhen, F Wong-Staal - Annual Review of Genetics, 1999 - genet.annualreviews.org
... AP-1, COUP-TF, RAR, NRT1/2, T cell factor B, myb, and GATA3 (8, 46 ... The NF- B/rel
proteins upregulate transcription in response to a variety of stimuli including ...
Cited by 42 - Web Search - genet.annualreviews.org - ncbi.nlm.nih.gov

NF-{kappa} B Activation in Airways Modulates Allergic Inflammation but Not Hyperresponsiveness - Full text - MIT Libraries
ME Poynter, R Cloots, T van Woerkom, KJ Butnor, P … - The Journal of Immunology, 2004 - jimmunol.org
... NF- B and rel proteins: Evolutionarily conserved mediators of immune responses ... A
critical role for NF- B in GATA3 expression and TH2 differentiation in allergic ...
Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »