MYCC and MYCN oncogene amplification in medulloblastoma
N Aldosari, SH Bigner, PC Burger, L Becker, JL … - Arch Pathol Lab Med, 2002 - arpa.allenpress.com
... 9, and each red spot corresponded to the specific probe for MYCC or MYCN (Figure
1 ... for chromosome 9 in approximately 50% of the cells counted; the rest of the ...
Cited by 22 - Web Search - arpa.allenpress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Expression of B-myb in neuroblastoma tumors is a poor prognostic factor independent from MYCN … - Full text - MIT Libraries
G Raschella, V Cesi, R Amendola, A Negroni, B … - Cancer Res, 1999 - cancerres.aacrjournals.org
... an aggressive therapy similar to that tested in patients with MYCN amplification
(24 ... of c-myb expression was somehow surprising; an explanation may rest in the ...
Cited by 6 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

… of multiple genes in neuroblastic tumours: relationship with MYCN amplification and allelic status … - Full text - MIT Libraries
P Gonzalez-Gomez, MJ Bello, J Lomas, D Arjona, ME … - Eur J Cancer, 2003 - biotools.net
... The overall MI value for the neuroblastomas with concurrent MYCN amplification and
1p ... significance when compared with the corresponding MI value in the rest ...
Cited by 9 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Meeting Summary for Advances in Neuroblastoma Research-2000
M SUMMARY - Medical and Pediatric Oncology, 2000 - doi.wiley.com
... sub- mitted, of which 62 were oral presentations and the rest were presented as ... of
allelic gain included ampli- fication of 2p24 around the MYCN proto-oncogene ...
Web Search - doi.wiley.com

Outcome of high-risk neuroblastoma using a dose intensity approach: Improvement in initial but not …
V Castel, A Canete, S Navarro, P Garcia-Miguel, C … - Medical and Pediatric Oncology, 2001 - doi.wiley.com
... Children of 1±2 years had clinical factors similar as those of the rest of the patients,
but MYCN was studied less often than in older patients (58%), it was ...
Cited by 9 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Retinoic-acid-resistant neuroblastoma cell lines show alteredMYC regulation and high sensitivity to …
CP Reynolds, Y Wang, LJ Melton, PA Einhorn, DJ … - Medical and Pediatric Oncology, 2000 - doi.wiley.com
... myc expression (MYCN or c-myc), and because increasing myc expression by
MYCN-transduction also ... seen with pulse (1 week of 4-HPR, 2 weeks rest) dose escalation ...
Cited by 11 - Web Search - nant.org - reprints.nant.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Assessment of an abdominal mass
MWB Arush, JM Pearce - Urol Clin North Am, 2000 - content.karger.com
... these secrete catecholamines and need further intervention – the rest are ‘incidental ...
Molecular biologic markers like MYCN gene amplification confer a worse ...
Web Search - content.karger.com

Neuroblastic and Schwannian stromal cells of neuroblastoma are derived from a tumoral progenitor … - Full text - MIT Libraries
J Mora, NK Cheung, G Juan, P Illei, I Cheung, M … - Cancer Res, 2001 - cancerres.aacrjournals.org
... NB and 1 stage 4 tumor with multiple clones identified by FISH for MYCN (Tumor
#2123 ... The rest of the tumors studied had two signals for chromosome 1 and 17 in ...
Cited by 15 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

paediatrische Onkologie - Full text - MIT Libraries
A Laengler, R Herold, P Kaatsch, R Souchon, C … - klinikarzt, 2005 - thieme-connect.com
... ma- chen dagegen im Kindesalter nur ei- nen verschwindend kleinen Rest von etwa ...
MYCN-Gen Das Onkogen MYCN („myc oncogene, located at chromosome 2“) steuert ...
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Ganglioneuroblastoma Metastatic to the Orbit.
TEMD Johnson, SRMD Toledano - Ophthalmic Plastic & Reconstructive Surgery, 2003 - op-rs.com
... The rest of her ophthalmic examination was normal, and no abdominal ... Unfortunately,
MYCN amplification studies could not be performed because of contamination ...
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BRIEF REPORT Predilection of Retinoblastoma Metastases for the Mandible
J Pandya, K Valverde, E Heon, S Blaser, BL Gallie, … - Med Pediatr Oncol, 2002 - doi.wiley.com
... the metastases go to the brain, CSF and head and neck, and the rest, to bone ...
eye.The long interval to metastasis may be due to the lack of MYCN oncogene ampli ...
Cited by 2 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Telomerase Activity as a Prognostic Factor in Neuroblastomas - Full text - MIT Libraries
CJ Streutker, P Thorner, N Fabricius, S Weitzman, … - Pediatric and Developmental Pathology, 2001 - springerlink.com
... had been previously untreated and all relevant prog- nostic factors were known
(MYCN copy number ... The rest of the patients were followed for a minimum of 8 months ...
Cited by 13 - Web Search - ncbi.nlm.nih.gov

Autologous Stem Cell Transplantation for High-Risk Neuroblastoma
JG Villablanca, KK Matthay, CP Reynolds, R Gerbing … - mmserver.cjp.com
... only, and 19 <1 year of age with ES stage IV and MYCN amplification. ... followed by
a 14-day rest, beginning at day 84 after completion of chemoradio- therapy. ...
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Mass Screening for Neuroblastoma in Japan: Lessons Learned and Future Directions
J Fukuoka - md.huji.ac.il
... Biological fea- tures studied included MYCN gene amplification, DNA ploidy, Shi-
mada ... The information concerning chemo- therapyin the rest of 20 is unknown. ...
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Shc Family Expression in Neuroblastoma: High Expression of shcC Is Associated with a Poor Prognosis … - Full text - MIT Libraries
E Terui, T Matsunaga, H Yoshida, K Kouchi, H … - Clinical Cancer Research, 2005 - clincancerres.aacrjournals.org
... of MYCN. We could not detect shcC in earlier stage samples, although six stage 4
tumors expressed substantially higher levels of shcC than the rest of the ...
Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

Biological aspects of neuroblastoma screening
GM Brodeur, PF Ambros, MC Favrot - Medical and Pediatric Oncology, 1998 - doi.wiley.com
... 3. Three patients had 1p LOH, without MYCN ampli- fication: stages 1, 2B, 4S (CR
at ... 32 months; one is in very good partial response (VGPR); and the rest are in ...
Cited by 12 - Web Search - doi.wiley.com

Colloquy on Neuroblastoma Screening: Is there a future for neuroblastoma mass screening?
F Bessho - Medical and Pediatric Oncology, 1998 - doi.wiley.com
... which was almost 3 times as high as those in the rest of the ... They demonstrate that
the NBLs found by screening had favorable prognostic factors MYCN onco- gene ...
Cited by 1 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Fluorescence in situ hybridization techniques for the rapid detection of genetic prognostic factors … - Full text - MIT Libraries
CPF Taylor, NP Bown, AG McGuckin, J Lunec, AJ … - Br. J. Cancer, 2000 - nature.com
... 2 (A) Chromosome 1 centromere; (B) CT4-1 (distal 1p probe); (C) MYCN probe; (D ...
Twenty-five per cent are probably tetraploid cells and the rest are diploid ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Differentiating Agents in Pediatric Malignancies: Retinoids in Neuroblastoma - Full text - MIT Libraries
CP Reynolds - Current Science, 2000 - current-reports.com
... One of the most potent differentiation inducers for human neuroblastoma in vitro
is retinoic acid [1]. Treatment of both MYCN gene-amplified and nonamplified ...
Cited by 17 - Web Search - current-reports.com - ncbi.nlm.nih.gov

The Role of Angiogenesis in Neuroblastoma
HM Katzenstein - Am J Cancer, 2003 - ingentaconnect.com
... rhexis index, histopathology, and MYCN amplification. Integrin ment with chemotherapy. ...
that this approach is associated with repetitive rest periods follow- ...
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Tumors of the neuroblastoma group - Full text - MIT Libraries
H Shimada, A Nakagawa - International Journal of Clinical Oncology, 1999 - springerlink.com
... represent a true neoplastic process and how many are an embryonic rest, the vast ...
such as age greater than 1 year, metastatic disease, and MYCN amplification. ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov

Pathology and biology guidelines for resectable and unresectable neuroblastic tumors and bone marrow …
PF Ambros, IM Ambros - Medical and Pediatric Oncology, 2001 - doi.wiley.com
... tumor cell suspensions which may serve for cytogenetics, assessment of MYCN and
chromosome ... After this procedure, the rest of the surgical specimen can be ®xed ...
Cited by 17 - Web Search - doi.wiley.com

Terminology and morphologic criteria of neuroblastic tumors
H Shimada, IM Ambros, LP Dehner, J Hata, VV Joshi, … - Cancer, 1999 - doi.wiley.com
... whether these neuroblastic “tumorlets” are persistent embryonic rest, hyperplasia,
or ... chromosome 1 short arm, lack of MYCN amplification, and near-triploidy ...
Cited by 75 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Ring Nebula and Bipolar Outflows Associated with the B 1. 5 Supergiant Sher 25 in NGC 3603 - Full text - MIT Libraries
W Brandner, EK Grebel, YH Chu, K Weis - The Astrophysical Journal, 1997 - journals.uchicago.edu
... km s -1 . The absolute calibration with respect to the local standard of rest (LSR)
has ... nebula as has been observed in the young planetary nebula MyCn 18 (Sahai ...
Cited by 21 - Web Search - arxiv.org - astro.ruhr-uni-bochum.de - astro.rub.de - all 9 versions »

HOMOZYGOUS DELETION AND EXPRESSION OF PTEN AND DMBT1 IN HUMAN PRIMARY NEUROBLASTOMA AND CELL LINES - Full text - MIT Libraries
JS Castresana - Int. J. Cancer, 2004 - doi.wiley.com
... 1, mutated in multiple advanced cancers-1; MXI1, max interacting protein-1; MYCN,
v-myc ... We could not find any other positive controls for the rest of the DMBT1 ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

‘‘A. Kyriakou,’’Athens, Greece
M Baka, MH Collins, S Editor, GJ D’Angio - Med Pediatr Oncol, 2003 - doi.wiley.com
... There were no abnormal lymph nodes and the rest of the abdomen was negative ... with
large areas of hemorrhagic necrosis and calcifications, stage I. MYCN and DNA ...
Web Search

Development, characterization and therapy of a disseminated model of childhood neuroblastoma in SCID … - Full text - MIT Libraries
J Thompson, SM Guichard, PJ Cheshire, LB Richmond, … - Cancer Chemotherapy and Pharmacology, 2001 - springerlink.com
... MYCN gene ampli®cation was investigated by simulta ... Drug was administered daily for
5 days on two consecutive weeks followed by a 9-day rest period, referred to ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov

Histopathology defines prognostic subsets of ganglioneuroblastoma, nodular
S Umehara, A Nakagawa, KK Matthay, JN Lukens, RC … - Cancer, 2000 - doi.wiley.com
... ex- cluded due to missing MYCN data). The “high risk” class included the patients
with Stage IV disease who were age 1 year at diagnosis. The rest of the ...
Cited by 6 - Web Search - reprints.nant.org - nant.org - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Detection of unidentified chromosome abnormalities in human neuroblastoma by spectral karyotyping( …
N Cohen, DR Betts, L Trakhtenbrot, FK Niggli, N … - Genes Chromosomes and Cancer, 2001 - doi.wiley.com
... MYCN ... Figure 1. Case 6. A: SKY, spectra-based colors; classification colors of
chromosomes 13, 14, 15, and 21 centromeres differ from the rest of the chromosome ...
Cited by 9 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

An Integrated 5-Mb Physical, Genetic, and Radiation Hybrid Map of a 1p36. 1 Region Implicated in …
AML EXTL, OP RH - GENES, CHROMOSOMES & CANCER, 2000 - doi.wiley.com
... of 564 bp) was identical to the RH gene; however, the rest of the ... cell lines suggests
that a tumor suppressor locus associ- ated with MYCN amplification maps ...
Cited by 8 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genetic alterations of brain tumors
K von Ammon, U Roelcke - J Neuro Oncol, 1994 - springerlink.com
... In this way, MYCN-gene was amplified [11, 12], which is associated with neuroblastoma ...
to host or viral proteins) are not able to induce cell cycle ar- rest. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Shedding Light on the Dark Side of the Genome: Overlapping Genes in Higher Eukaryotes
S Boi, G Solda, ML Tenchini - Current Genomics, 2004 - dx.doi.org
... classes was not significantly different from that of the rest of human ... MYCN v-myc
myelocytomatosis viral related oncogene MYCNOS DNA-binding transcriptional ...
Cited by 3 - Web Search - ingentaconnect.com

Wilms’tumor and neuroblastoma
BZ Morgenstern, AP Krivoshik, V Rodriguez, PM … - Acta Paediatr Suppl, 2004 - taylorandfrancis.metapress.com
... Haber PS, Marshall GM, Haber M. Prognostic significance of MYCN oncogene expression ...
Wilms’ tumor or monolateral Wilms’ tumor with nephrogenic rest on the ...
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Wilms’tumor and neuroblastoma
BZ Morgenstern, AP Krivoshik, V Rodriguez, PM … - dx.doi.org
... Haber PS, Marshall GM, Haber M. Prognostic significance of MYCN oncogene expression ...
Wilms’ tumor or monolateral Wilms’ tumor with nephrogenic rest on the ...
Web Search

STAGNATION KNOTS IN PLANETARY NEBULAE
W Steffen, JA Lopez, AJ Lim - Ionized Gaseous Nebulae, a Conference to Celebrate the 60th …, 2002 - astrosmo.unam.mx
... shock, the stagnation knot moves roughly at the same speed as the rest of the bow ...
We find that, in agreement with observations (eg, MyCn 18, O’Connor et al. ...
View as HTML - Web Search - adsabs.harvard.edu

FLIERs as Stagnation Knots from Post-AGB Winds with Polar Momentum Deficiency - Full text - MIT Libraries
W Steffen, JA Lopez, A Lim - The Astrophysical Journal, 2001 - journals.uchicago.edu
... shocked fast wind (left) and the shocked external medium (right) in the rest frame
of ... velocities over 600 km s -1 , as observed in the case of MyCn 18 (Bryce ...
Web Search - arxiv.org - arxiv.org - adsabs.harvard.edu - all 5 versions »

Metastatic Neuroblastoma Presenting with Binocular Blindness from Intracranial Compression of the …
C Lau, J Juan, JD Trobe, RE Ruiz, RW Cho, DS … - Journal of Neuro-Ophthalmology, 2004 - jneuro-ophthalmology.com
... The rest of his physical examination was unremarkable. ... with a poor prognosis are
unfavorable histology, amplification of the MYCN oncogene, characteristic ...
Web Search - jneuro-ophthalmology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Symbiotic Miras can do it
RLM Corradi, M Livio, HE Schwarz, U Munari - Arxiv preprint astro-ph/0001234, 2000 - arxiv.org
... mass amounts to about 1% of the Mira wind; the rest distributes around ... The inner
nebula is strikingly similar to the prototypical bipolar PN MyCn 18 (Sahai & ...
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Metastatic Primitive Neuroectodermal Tumour of the Ovary: Successful Treatment With Mega-Dose …
ER Lawlor, JI Murphy, PH Sorensen, CJ Fryer - Medical and Pediatric Oncology, 1997 - doi.wiley.com
... primitive neuroectodermal tumours [2]. Furthermore, there was no evidence of MYCN
gene amplification ... a dose of 160mg/m 2 . After 2 days of rest, the collected ...
Cited by 1 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

FLIERs as stagnation knots from partially collimated outflows
W Steffen, JA Lopez - Arxiv preprint astro-ph/9909261, 1999 - arxiv.org
... the stagnation knot will move roughly at the same speed as the rest of the bow ... of
roughly linear increase of speed with distance, as observed in MyCn 18 (Bryce ...
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Targeted inhibition of NMYC by peptide nucleic acid in N-myc amplified human neuroblastoma cells: … - Full text - MIT Libraries
A PESSION, R TONELLI, R FRONZA, E SCIAMANNA, R … - INTERNATIONAL JOURNAL OF ONCOLOGY, 2004 - 147.52.72.117
... UTR sites or sequences complementary to the start site or the rest of the ... 2. Schwab
M: Amplified MYCN in human neuroblastoma: para- digm for the translation of ...
Cited by 2 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Database of mRNA gene expression profiles of multiple human organs - Full text - MIT Libraries
CG Son, S Bilke, S Davis, BT Greer, JS Wei, CC … - Genome Research, 2005 - genome.org
... Adrenal, kidney, pancreas, lung, and spleen clustered separately from the rest of
the ... NB tumors of different stages (1 through 4 including MYCN amplified tumors ...
Web Search - dx.doi.org - genome.org - ncbi.nlm.nih.gov

Motif-Based Protein Sequence Classification Using Neural Networks - Full text - MIT Libraries
K Blekas, DI Fotiadis, A Likas - Journal of Computational Biology, 2005 - dx.doi.org
... The obtained gradient-log-probability vectors are applied to an SVM to identify
the decision boundary between the family and the rest of the protein universe. ...
Web Search - liebertonline.com - cs.uoi.gr - ncbi.nlm.nih.gov - all 6 versions »

FLIERS AS STAGNATION KNOTS IN PLANETARY NEBULAE
W Steffen, JA Lopez, AJ Lim - Emission Lines from Jet Flows, Isla Mujeres, QR, Mexico, …, 2002 - astrosmo.unam.mx
... up to velocities over 600km s −1 , as observed in the case of MyCn 18 (Bryce et ...
shock, the stagnation knot moves roughly at the same speed as the rest of the ...
View as HTML - Web Search - adsabs.harvard.edu

Neuroblastoma metastatic to the central nervous system
K Kramer, B Kushner, G Heller, NKV Cheung - Cancer, 2001 - doi.wiley.com
... However, progressive disease involving the CNS was docu- mented in 11 patients,
including 8 from Group 127 and 3 from in the rest of the patients (Table 1 ...
Cited by 15 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Advanced Cancer Genetics in Neurosurgical Research.
M Taylor, C Raffel, J Bayani, PRT Marrano, TGMD … - Neurosurgery, 2003 - neurosurgery-online.com
... B, FISH analysis of a neuroblastoma metaphase spread showing amplification of MYCN
(in red ... lasered are lifted away for further analysis, leaving the rest of the ...
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Post-transplant complications Long-term adverse effects on dentition in children with poor-risk …
P Hoelttae, S Alaluusua, UM Saarinen-Pihkala, J … - Bone Marrow Transplantation, 2002 - nature.com
... NBL were age over 1 year and dis- seminated disease, unfavorable histology, or MYCN
ampli- fication. ... dose was 12 Gy in three males and 10 Gy in the rest of the ...
Web Search

DIE MITTEILUNGEN VON GPOH UND KPOH
M des Kompetenznetzes - dx.doi.org
... sich auch in den Projekten »Prä- leukämische Knochenmark-Erkrankungen« und »Minimale
Rest- erkrankung« durch ... 6 MYCN-Doppelbestimmung beim Neuroblastom 6 ...
Web Search - kinderkrebsinfo.de - kinderkrebsinfo.de

Departure from Axisymmetry in Planetary Nebulae - Full text - MIT Libraries
N Soker, S Rappaport - The Astrophysical Journal, 2001 - journals.uchicago.edu
... can be seen in Hubble Space Telescope (HST) images: the PN MyCn 18 (the ... Soker (1999)
analyzes these 19 PNs, and the rest for which no companions were found ...
Cited by 2 - Web Search - arxiv.org - adsabs.harvard.edu - adsabs.harvard.edu

Pediatric genitourinary tumors.
D Herz, D McLellan, K Garrels, PA Merguerian - Current Opinion in Oncology, 2000 - co-oncology.com
... lesions in two patients (7%), which showed a nephrogenic rest in one. ... described to
be overexpressed in alveolar rhabdomyosarcoma (PAX3-FKHR, MYCN, and CDK4) [35 ...
Web Search - co-oncology.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries