Studies on Pax2 gene in kidney development
D Kim - bric.postech.ac.kr
... If a genetic change occurs in the hyperplastic rest cells, they are able to be a
malignant Wilms’ tumor. Even if Pax2 overexpression have a potential to ...
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A series of no isthmus (noi) alleles of the zebrafish pax2. 1 gene reveals multiple signaling events … - Full text - MIT Libraries
K Lun, M Brand - Development, 1998 - dev.biologists.org
... A) Schematic drawing of the Pax2.1 protein ... deletion leads to the loss of six amino
acids in helix II of the N-terminal paired domain, but leaves the rest of the ...
Cited by 85 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Expression of Pax2 and patterning of the chick inner ear
MR Hutson, JE Lewis, D Nguyen-Luu, KH Lindberg, KF … - J. Neurocytol, 1999 - kluweronline.com
... cavity. However, the Pax2 expression pattern is plastic in the rest of the
otic epithelium after 180 ◦ rotation of the otocyst. Pax2 ...
Cited by 20 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Homonucleotide expansion and contraction mutations of PAX2 and inclusion of Chiari 1 malformation as … - Full text - MIT Libraries
LA Schimmenti, HH Shim, JD Wirtschafter, VA … - Hum Mutat, 1999 - doi.wiley.com
... The rest of the physi- cal exam was normal. Mutation Analysis Genomic DNA was
isolated from each indi- vidual and analyzed for PAX2 mutations. ...
Cited by 8 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

The zebrafish buttonhead-like factor Bts1 is an early regulator of pax2. 1 expression during mid- … - Full text - MIT Libraries
A Tallafuss, TP Wilm, M Crozatier, P Pfeffer, M … - Development, 2001 - dev.biologists.org
... Note that at five somites, the pax2.1-dependent markers eng3 and pax5 are also ... to
the mid-hindbrain level and tail bud and extinguishes from the rest of the ...
Cited by 11 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Tlx genes make an exciting choice - Full text - MIT Libraries
S Anderson - Nature Neuroscience, 2004 - nature.com
... In the mantle region, Tlx1/3 repress Pax2 expression and promote glutamatergic
differentiation. ... part, unless it is clearly in continuity with the rest of the ...
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Midline signaling in the primordium of the zebrafish anterior central nervous system - Full text - MIT Libraries
K HATTA, AW POSCHEL, CB KIMMEL - Developmental Biology, 1994 - pnas.org
... forebrain with-that along the rest of the neuraxis. ... As forpax6, the extent of pax2
expression along the anterioposterior axis seems unaffected by the mutation. ...
Cited by 50 - Web Search - pubmedcentral.nih.gov - pnas.org - ncbi.nlm.nih.gov

Ocular and cerebellar defects in zebrafish induced by overexpression of the LIM domains of the islet … - Full text - MIT Libraries
Y Kikuchi, H Segawa, M Tokumoto, T Tsubokawa, Y … - Neuron, 1997 - invivo.caltech.edu
... hr and 30 hr embryos. Pax2 expression pattern in the rest of the brain
remained identical to that in the normal embryos. Page 7. ...
Cited by 23 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

The zebrafish pronephros: a genetic system for studies of kidney development - Full text - MIT Libraries
IA Drummond - Pediatric Nephrology, 2000 - springerlink.com
... In recent experiments analyzing nephron development in the zebrafish pax2.1 mutant ...
In zebrafish, the nephron pri- mordia rest directly on the ventral surface ...
Cited by 17 - Web Search - receptor.mgh.harvard.edu - danio.mgh.harvard.edu - ncbi.nlm.nih.gov - all 5 versions »

Primary, Nonsyndromic Vesicoureteric Reflux and Its Nephropathy Is Genetically Heterogeneous, with a … - Full text - MIT Libraries
SA Feather, S Malcolm, AS Woolf, V Wright, D … - The American Journal of Human Genetics, 2000 - journals.uchicago.edu
... 1998) such as the renal-coloboma syndrome, which is caused by PAX2 mutations on ... as
indicated in figure 1. This prompted further inquiry into the rest of the ...
Cited by 32 - Web Search - ncbi.nlm.nih.gov

Expression of ZIC genes in the development of the chick inner ear and nervous system - Full text - MIT Libraries
SJ Warner, MR Hutson, SH Oh, LM Gerlach-Bank, MI … - Developmental Dynamics, 2003 - doi.wiley.com
... However, in the rest of the otic epi- thelium, Pax2 expression reverted to a pattern
in which it was higher on the hindbrain side, as in the normal expression ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov

The role of PAX 2 in normal and abnormal development of the urinary tract - Full text - MIT Libraries
MR Eccles - Pediatric Nephrology, 1998 - springerlink.com
... cancerous stage [44]. It has been shown that PAX2 is strongly expressed
in nephro- genic rest tissue [23]. Further support for the ...
Cited by 13 - Web Search - ncbi.nlm.nih.gov

Early nephron formation in the developing mouse kidney - Full text - MIT Libraries
JBL BARD, A GORDON, L SHARP, WI SELLERS - Journal of Anatomy, 2001 - journals.cambridge.org
... Examination of E12 Pax2-stained specimens has confirmed that this transcription
factor is expressed in ... and in the ducts themselves, but not in rest of the MM. ...
Cited by 8 - Web Search - blackwell-synergy.com - homepage.mac.com - mac-huwis.lboro.ac.uk - all 6 versions »

Computer simulation of left ventricular filling flow: Impact study on echocardiograms
J Vierendeels, K Riemslagh, E Dick, P Verdonck - COMPUT CARDIOL. pp. 177-180. 1999, 1999 - ieeexplore.ieee.org
... that initially the flow is at rest and that LV relaxation is homogeneous. ... LV relaxation
(2,x2), higher LV stiffness (E,,,x2) and higher atrial pressure (Pax2). ...
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Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations - Full text - MIT Libraries
Y Imai, WS Talbot - Genesis, 2001 - doi.wiley.com
... 1C). Most of these embryos lysed during somitogenesis, and the rest of them had
a ... Early in segmentation (3-somite stage, 11 h), pax2.1 expression in midbrain ...
Cited by 6 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Patterning of the mammalian cochlea - Full text - MIT Libraries
R Cantos, LK Cole, D Acampora, A Simeone, DK Wu - Proceedings of the National Academy of Sciences - pnas.org
... 2A). In contrast, single injections to either the utricle or ampulla fill the rest
of the ... of the cochlea (Table 1). For example, the absence of Pax2, a paired ...
Cited by 29 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

The dysregulated glomerular cell growth in Denys–Drash syndrome - Full text - MIT Libraries
AH Yang, JY Chen, BF Chen - Virchows Archiv, 2004 - springerlink.com
... to be capable of stimulating cell proliferation by the observations that PAX2 induced ...
The rest of the glomeruli in the DDS kidneys show complex morphological ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

New perspectives on the evolution of protochordate sensory and locomotory systems, and the origin of …
TC Lacalli - Philosophy Transactions of the Royal Society of London B, …, 2001 - journals.royalsoc.ac.uk
... Pax2/5/8 ... Motor neurons in the latter control the adult pharynx and gut, as well as
the rest of the body muscula- ture, so one expects that at least a subset of ...
Cited by 10 - Web Search - nbb.cornell.edu - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Feature Article Ontogeny of congenital anomalies of the kidney and urinary tract, CAKUT - Full text - MIT Libraries
Y Miyazaki, I Ichikawa - Pediatrics International, 2003 - blackwell-synergy.com
... In this regard, PAX2, a paired-box transcription factor, has been identified as
the ... beyond the initial budding stage, and throughout the rest of intrauterine ...
Cited by 1 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Mammalian sex determination: a molecular drama - Full text - MIT Libraries
A Swain, R Lovell-Badge - Development, 1999 - genesdev.org
... from the testes, which determine the sexual development of the rest of the ... also
contribute to the cells of the early gonad, although the Pax2 mutant phenotype ...
Cited by 134 - Web Search - mcb.berkeley.edu - mne.uni-karlsruhe.de - npb.ucdavis.edu - all 7 versions »

lim 6, a novel LIM homeobox gene in the zebrafish: Comparison of its expression pattern with lim 1 - Full text - MIT Libraries
R Toyama, IB Dawid - Developmental Dynamics, 1997 - doi.wiley.com
... that inhibits the DNA binding and transcriptional activity of the rest of the ... To
aid in localization, double-staining was performed with pax2, a marker of the ...
Cited by 19 - Web Search - doi.wiley.com - invivo.caltech.edu - ncbi.nlm.nih.gov - all 5 versions »

Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral … - Full text - MIT Libraries
F Muller, S Albert, P Blader, N Fischer, M … - Development, 2000 - dev.biologists.org
... and G,H, respectively), beginning from the diencephalon and extending into the rest
of the ... one would predict that netrin1 or the ventral eye marker pax2.1 can ...
Cited by 31 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Paradigm shift from classic anatomic theories to contemporary cell biological views of CAKUT - Full text - MIT Libraries
I Ichikawa, F Kuwayama, JC Pope, FD Stephens, Y … - Kidney International, 2002 - blackwell-synergy.com
... It is not well understood, however, how haploinsufficiency of Pax2 or Eya1 ... continues
beyond the initial budding stage, and throughout the rest of intrauterine ...
Cited by 13 - Web Search - ingentaconnect.com

Foxj 3, a novel mammalian forkhead gene expressed in neuroectoderm, neural crest, and myotome - Full text - MIT Libraries
H Landgren, P Carlsson - Developmental Dynamics, 2004 - doi.wiley.com
... dicted DNA binding domain with those from the rest of the forkhead family ... mount in
situ hybridizations with probes for Foxj3, Foxd3, Twist1, Pax2, Myod1, and ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Development and pathology: the Pax gene - Full text - MIT Libraries
C Berry - J Pathol, 2002 - doi.wiley.com
... patterns (although Pax1 and Pax9 have a wider range than the rest of the ... edge of
the dermatomyotome into the limb bud fails to occur [7]. Pax2 is essential for ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Origin of the paired domain - Full text - MIT Libraries
R Breitling, JK Gerber - Development Genes and Evolution, 2000 - springerlink.com
... Accession numbers are: human Pax1, P15863; mouse Pax2, P32114; quail Pax3, O13081;
human Pax6 ... plus Pax1–9/meso and the rest of the proteins, in accor- dance ...
Cited by 8 - Web Search - brc.dcs.gla.ac.uk - ncbi.nlm.nih.gov

Midline signals regulate retinal neurogenesis in zebrafish - Full text - MIT Libraries
I Masai, DL Stemple, H Okamoto, SW Wilson, G … - Neuron, 2000 - ucl.ac.uk
... outer nuclear layer was variably present, cells through- out the rest of the ... Figure
5. ath5 Expression Is Closely Associated with pax2.1- Expressing Optic ...
Cited by 41 - View as HTML - Web Search - ncbi.nlm.nih.gov

TBX 1 is required for inner ear morphogenesis - Full text - MIT Libraries
F Vitelli, A Viola, M Morishima, T Pramparo, A … - Human Molecular Genetics, 2003 - hmg.oupjournals.org
... while expression of non-overlapping markers is conserved (Lfng, Pax2 ventral–medial ...
with the exception of Fgf10, are expressed normally in the rest of the ...
Cited by 5 - Web Search - biolchem.ucla.edu - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Pre-pattern in the pronephric kidney field of zebrafish - Full text - MIT Libraries
FC Serluca, MC Fishman - Development, 2001 - dev.biologists.org
... posterior cells contribute to the nephric duct, and these express pax2.1 and ... structural
elements of organs may be selectively removed leaving the rest of the ...
Cited by 20 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Six 3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos - Full text - MIT Libraries
O Lagutin, CC Zhu, Y Furuta, DH Rowitch, AP … - Developmental Dynamics, 2001 - doi.wiley.com
... however, Six3 expression seems to be independent of Pax6 in the rest of the ... decided
to ectopicaly express Six3 under the control of the Pax2 promoter element ...
Cited by 20 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Interactions between the middle and inner ear in patients with ear malformations
G Granstroem - Audiological Medicine, 2004 - dx.doi.org
... The rest occur in combination with a syndrome of which several are hereditary. ... A
candidate gene for the CHARGE association could be the PAX2 gene (13). ...
Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ingentaconnect.com

Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain … - Full text - MIT Libraries
M Carl, J Wittbrodt - Development, 1999 - dev.biologists.org
... (C,D) The expression of Pax2 and (E ... suggests that the mechanisms patterning the MHB
in AP direction relate to those employed in DV patterning in the rest of the ...
Cited by 18 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Methylation profiling of CpG islands in human breast cancer cells - Full text - MIT Libraries
T Huang, MR Perry, DE Laux - Human Molecular Genetics, 1999 - hmg.oupjournals.org
... HBC-17, 0.75, HBC-18, 1.30, PAX2, M89470. HBC-19, 0.90, PAX7, AL021528. HBC-20,
0.45, CGI clone 67g9, Z62363. ... This approach was applied for the rest of the CpG island ...
Cited by 96 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Evolving concepts in human renal dysplasia - Full text - MIT Libraries
AS Woolf, KL Price, PJ Scambler, PJD Winyard - J Am Soc Nephrol, 2004 - jasn.org
... renal failure in children have patent urinary tracts, whereas the rest have obstructive ...
PAX2 and BCL2 are cell survival genes (33,34) normally expressed as ...
Cited by 4 - Web Search - jasn.org - jasn.org - ncbi.nlm.nih.gov - all 6 versions »

Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem Cells - Full text - MIT Libraries
Y Yan, D Yang, ED Zarnowska, Z Du, B Werbel, C … - Stem Cells, 2005 - stemcells.alphamedpress.org
... Pax2 (5'-ATGTTCGCCTGGGAGATTCG,-3' 5'-GCAAGTGCTTCCGCAAACTG-3', 361 bp). ... V rest and
action potentials (APs) were examined in current-clamp mode. ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

Genes involved in forebrain development in the zebrafish, Danio rerio - Full text - MIT Libraries
CP Heisenberg, M Brand, YJ Jiang, RM Warga, D … - Development, 1996 - dev.biologists.org
... pax[zf-a]) (Macdonald et al., 1994; 1:400), anti-pax2 (also called pax[zf-b]) (Mikkola
et al., 1992; Püschel et al., 1992b; 1:100), anti- ntl (Schulte-Merker ...
Cited by 35 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for … - Full text - MIT Libraries
D Acampora, V Avantaggiato, F Tuorto, P Briata, G … - Development, 1998 - dev.biologists.org
... The rest of the manipulations were performed according to the streptavidin- biotin ...
The Wnt1, Pax2 and Fgf8 probes are the same as previously described (Acampora ...
Cited by 79 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry - Full text - MIT Libraries
BW Bisgrove, JJ Essner, HJ Yost - Development, 2000 - dev.biologists.org
... used include: lefty1, lefty2 and pitx2 (Bisgrove et al., 1999); cyclops (ndr2,
Rebagliati et al., 1998a); preproinsulin (Milewski et al., 1998); pax2 (pax(zf-b ...
Cited by 52 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Regulation of zebrafish primordial germ cell migration by attraction towards an intermediate target - Full text - MIT Libraries
G Weidinger, U Wolke, M Koeprunner, C Thisse, B … - Development, 2002 - dev.biologists.org
... 1994), papc (pcdh8 – Zebrafish Information Network) (Yamamoto et al., 1998),
pax2.1 (pax2a ... lateral lines at the head-trunk border, while the rest are located ...
Cited by 22 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Region-specific effects of glia on neuronal induction and differentiation with a focus on … - Full text - MIT Libraries
AC Hall, H Mira, J Wagner, E Arenas - Glia, 2003 - doi.wiley.com
... astrocytes have been reported to express patterning genes, including Pax2, Wnt-1 ...
developing ventral mesencephalon (VM) remains unclear: (1) RG at rest: Early in ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

Wnt-6 is expressed in the ureter bud and induces kidney tubule development in vitro - Full text - MIT Libraries
P Itaeranta, Y Lin, J Peraesaari, G Roel, O … - genesis, 2002 - doi.wiley.com
... becomes induced in vivo as the expression of the early molecular markers Pax2 and
N ... The rest of the embryo was used for genotyping by PCR according to Stark et ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Potential Biological Role of Transforming Growth Factor-ss1 in Human Congenital Kidney Malformations - Full text - MIT Libraries
SP Yang, AS Woolf, HT Yuan, RJ Scott, RA Risdon, … - American Journal of Pathology, 2000 - ajp.amjpathol.org
... For the rest of the experiments in this study, therefore, we used ... Exogenous TGF-ß1
induced a reproducible decrease in immunoreactive PAX2, BCL2, and PCNA ...
Cited by 18 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte … - Full text - MIT Libraries
C Bingham, S Ellard, TRP Cole, KE Jones, LIS Allen … - Kidney International, 2002 - blackwell-synergy.com
... There is no known history of diabetes in the rest of the family but ... expression of
a single autosomal dominant gene [2]. The transcription factor PAX2 has been ...
Cited by 17 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Dosage requirement and allelic expression of PAX6 during lens placode formation - Full text - MIT Libraries
CD van Raamsdonk, SM Tilghman - Development, 2000 - dev.biologists.org
... Recently, increased apoptosis was found to be correlated with reduced Pax2 gene
dosage ... the wild-type placode, where the placode connects with the rest of the ...
Cited by 25 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Comparative genomics provides evidence for an ancient genome duplication event in sh
JS Taylor, Y Van de Peer, I Braasch, A Meyer - Phil. Trans. R. Soc. Lond. B, 2001 - journals.royalsoc.ac.uk
... The goal of our study was to use a phylogenetic approach to evaluate the hypothesis
that the `extra’ Hox genes and the rest of the genome in ¢shes were ...
Cited by 102 - Web Search - evolutionsbiologie.uni-konstanz.de - mit.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Retinoid-dependent gene expression regulates early morphological events in the development of the … - Full text - MIT Libraries
DL Stull, KC Wikler - The Journal of Comparative Neurology, 2000 - doi.wiley.com
... by our finding that these ectopic pieces of ventral retina express Pax2, a marker
of ... of the ventral epithelium that have been segregated from the rest of the ...
Cited by 12 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit … - Full text - MIT Libraries
C Irving, I Mason - Development, 2000 - dev.biologists.org
... 1A-C; Table 1); by contrast, Pax2 was induced only in a small number of ... For example,
it is distinguished from both midbrain and the rest of the hindbrain by ...
Cited by 62 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Aphakia(ak), a mouse mutation affecting early eye development: Fine mapping, consideration of …
C Grimm, B Chatterjee, J Favor, T Immervoll, J … - Developmental Genetics, 1998 - doi.wiley.com
... The ak mutation does not affect the expression pattern of Pax2, which is important
during ... sac-like structure in the eye cup remains present for the rest of the ...
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Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and … - Full text - MIT Libraries
M Willem, N Miosge, W Halfter, N Smyth, I Jannetti … - Development, 2002 - dev.biologists.org
... membrane, but independent of a proliferation defect or differentiation processes
regulated by Pax2. ... 6C), whereas the rest had either a reduced (25%) or missing ...
Cited by 26 - Web Search - mstp.nwu.edu - mstp.northwestern.edu - ncbi.nlm.nih.gov - all 7 versions »

Homeobox genes in the genetic control of eye development
G Lupo, M Andreazzoli, G Gestri, Y Liu, RQ He, G … - Int. J. Dev. Biol, 2000 - ijdb.ehu.es
... by a delay in neuronal differentiation when com- pared to the rest of the ... well character-
ized cyclops mutant, the paired-like homeobox gene pax2 - a specific ...
Cited by 8 - View as HTML - Web Search - ijdb.ehu.es - ncbi.nlm.nih.gov - Get it from MIT Libraries