… expression of the neuron-restrictive silencer factor(NRSF)/REST in differentiating neurons disrupts … - Full text - MIT Libraries
AJ Paquette, SE Perez, DJ Anderson - Proceedings of the National Academy of Sciences - pnas.org
... page DM Kemp, JC Lin, and JF Habener Regulation of Pax4 Paired Homeodomain ... Bennett,
and RS Zukin Ischemic Insults Derepress the Gene Silencer REST in Neurons ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 … - Full text - MIT Libraries
A Abderrahmani, M Steinmann, V Plaisance, G … - Mol Cell Biol, 2001 - mcb.asm.org
... Indeed, the function of neuronal genes regulated by REST in pancreatic cells remains
unclear. However, genes such as BETA2/NEUROD1, Islet-1, Pax4, Pax6, Nkx2.2 ...
Cited by 11 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

The REST-mediated transcriptional repression requires the inhibition of Sp1
V Plaisance, G Niederhauser, F Azzouz, V Lenain, … - jbc.org
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of Sp1 ... Running title: REST inhibits the Sp1-mediated activation ...
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Identification of potential target genes for the neuron-restrictive silencer factor
CJ Schoenherr, AJ Paquette, DJ Anderson - Neurobiology, 1996 - dx.doi.org
... page DM Kemp, JC Lin, and JF Habener Regulation of Pax4 Paired Homeodomain ... Bennett,
and RS Zukin Ischemic Insults Derepress the Gene Silencer REST in Neurons ...
Cited by 127 - Web Search - gel.ym.edu.tw - pnas.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Origin of the paired domain - Full text - MIT Libraries
R Breitling, JK Gerber - Development Genes and Evolution, 2000 - springerlink.com
... One exception is the Pax4–6/eyeless subfamily which is extremely conserved, so that
an ... or Pax1–9/meso were shown to diverge first from the rest of Pax ...
Cited by 8 - Web Search - brc.dcs.gla.ac.uk - ncbi.nlm.nih.gov

Phosphorylation of the Transactivation Domain of Pax 6 by Extracellular Signal-regulated Kinase and … - Full text - MIT Libraries
I Mikkola, JA Bruun, G Bjoerkoey, T Holm, T … - J Biol Chem, 1999 - jbc.org
... Pax6, like Pax3, Pax4, and Pax7, also harbors a second DNA-binding domain, the paired ...
of the SpeI (made blunt)-HindIII fragment and ligation of the rest of the ...
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Role of histone and transcription factor acetylation in diabetes pathogenesis.
SG Gray, P De Meyts - Diabetes Metab Res Rev, 2005 - doi.wiley.com
... types. It has also been shown that the regulation of Pax4 expression involves
repression by NRSF/REST in INS-1 cells [83]. As NRSF ...
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Genetics of type 2 diabetes: insight from targeted mouse mutants
D Accili, Y Kido, J Nakae, D Lauro, BC Park - Curr. Mol. Med, 2001 - ingentaconnect.com
... mouse lacking both insulin and IR to put this question to rest has not ... glucagon or
earlier markers of pancreatic endocrine cells like PDX1, Pax4, Pax6, and ...
Cited by 11 - Web Search - bentham.org - bentham.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

High prevalence of glucose-6-phosphate dehydrogenase deficiency without gene mutation suggests a …
C Vaisse, F Mauvais-Jarvis, CA San Francisco - jcem.endojournals.org
... variants in the β-cell transcription factor PAX4 predispose to the disease
in a subset of ... were representative of the rest of the group. ...
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High Prevalence of Glucose-6-Phosphate Dehydrogenase Deficiency without Gene Mutation Suggests a … - Full text - MIT Libraries
E Sobngwi, JF Gautier, JP Kevorkian, JM Villette, … - The Journal of Clinical Endocrinology & Metabolism - jcem.endojournals.org
... that functional gene variants in the ß-cell transcription factor PAX4 predispose
to ... and whose baseline characteristics were representative of the rest of the ...
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Transcribing pancreas - Full text - MIT Libraries
H Edlund - Diabetes, 1998 - diabetes.diabetesjournals.org
... expressed in the presumptive pancreatic epithelium, as compared with the rest of
the ... fate choice and that in absence of Pax4, the default fate would be to ...
Cited by 157 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov

Lineage Commitment and Cellular Differentiation in Exocrine Pancreas
AL Means, SD Leach, SD Leach, F Alert - Pancreatology, 2001 - content.karger.com
... Mice lacking either Pax6, Pax4, or Nkx6.1 also show ongoing expression of Ngn3 ... migration
through the dor- sal mesentery, ultimately coming to rest within the ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

In vivo and in vitro development of mouse pancreatic b-cells in organotypic slices - Full text - MIT Libraries
T Meneghel-Rozzo, A Rozzo, L Poppi, M Rupnik - Cell Tissue Res, 2004 - springerlink.com
... knockout mouse models were reported showing early onset endocrine defects, eg, Pax4,
Pax6 and ... 1d, e) and presented about 10% of the islet; the rest were insulin ...
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Institut fuer Experimentelle Genetik GSF-Forschungszentrum fuer Umwelt und Gesundheit, Neuherberg
DBR Breitling - tumb1.biblio.tu-muenchen.de
Page 1. Institut für Experimentelle Genetik GSF-Forschungszentrum für Umwelt und
Gesundheit, Neuherberg Phylogenetische und bioinformatische Untersuchung der ...
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Ontogeny, differentiation and growth of the endocrine pancreas - Full text - MIT Libraries
J Peters, A J& x 000 FC rgensen, G Kl& x 000 F 6 … - Virchows Archiv, 2000 - springerlink.com
... the pdx-1 gene selectively lacked a pancreas [43], while the rest of the ... epithelium
at e9.0 defines two endocrine cell populations: cells expressing both Pax4 ...
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The role of PAX 2 in normal and abnormal development of the urinary tract - Full text - MIT Libraries
MR Eccles - Pediatric Nephrology, 1998 - springerlink.com
... PAX3 and PAX7 are in group III, with PAX4 and PAX6 in group IV [8]. All the ... It has
been shown that PAX2 is strongly expressed in nephro- genic rest tissue [23 ...
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Polymorphic Variations in the Neurogenic Differentiation-1, Neurogenin-3, and Hepatocyte Nuclear … - Full text - MIT Libraries
AE Jackson, PG Cassell, BV North, S Vijayaraghavan … - Diabetes, 2004 - diabetes.diabetesjournals.org
... type 2 diabetes (65% of the model), whereas the rest was due ... onset diabetic subjects
carrying homozygous mutations in transcription factors NeuroD1 and Pax4. ...
Cited by 2 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Production of Higgs particles through e e---> Hgg - Full text - MIT Libraries
SC Lee, WC Su, JR Roan - Phys Rev D, 1990 - link.aps.org
... The rest are given by Eqs. ... 37) E(Xh= -/2 (0° + 1,-i,O), A=+ which has to be consistent
with the choice made in computing PAx4, we have = g A(OA-lA )+ (a 2-b 2 ...
Cited by 1 - Web Search - adsabs.harvard.edu - ncbi.nlm.nih.gov

Pancreatic disorders and cystic fibrosis: Working Group Report of the First World Congress of …
R Couper, D Belli, P Durie, K Gaskin, J Sarles, S … - J Pediatr Gastroenterol Nutr, 2002 - jpgn.org
... Most therapy is palliative and relies on bowel rest, adequate hydration, and pain ...
The homeobox genes Isl-1, pax4, and pax6 govern murine islet cell formation ...
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Physical Conditions in the Initial Stages of the Expanding Universe - Full text - MIT Libraries
RA Alpher, JW Follin, RC Herman - Physical Review, 1953 - link.aps.org
... small x (high temperatures) the neutrino temperature approaches the temperature
of the rest of the ... Since limpex4= 2 (7/8)pax4, limpec2x4= 2 (7/8)p c2x4, Xt Bo ...
Cited by 2 - Web Search - adsabs.harvard.edu - adsabs.harvard.edu

Neurosecretory cells without neurosecretion: evidence of an independently regulated trait of the … - Full text - MIT Libraries
ML Malosio, R Benfante, G Racchetti, B Borgonovo, … - The Journal of Physiology, 1999 - jp.physoc.org
... REST: a mammalian silencer protein that restricts sodium channel gene expression
to ... The Pax4 gene is essential for differentiation of insulin-producing cells ...
Cited by 7 - Web Search - blackwell-synergy.com - jphysiol.org - ncbi.nlm.nih.gov

PAX6 mutation as a genetic factor common to aniridia and glucose intolerance - Full text - MIT Libraries
T Yasuda, Y Kajimoto, Y Fujitani, H Watada, S … - Diabetes, 2002 - diabetes.diabetesjournals.org
... paired domain and some residues of the linker region and lacks the rest. ... portable
repression domain and an E1A-responsive activation domain in Pax4: a possible ...
Cited by 14 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov

Lack of Association of the Ala 45 Thr Polymorphism and Other Common Variants of the NeuroD Gene With … - Full text - MIT Libraries
BG Report - Diabetes, 2004 - diabetes.diabetesjournals.org
... with type 1 diabetes, was subsequently genotyped in the rest of the ... diabetes-associated
mutations in the transcription factors BETA2/NEUROD1 and PAX4 in type ...
Cited by 5 - Web Search - intl-diabetes.diabetesjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells
S Material, Y Hori, X Gu, X Xie, S Kim - pubmedcentral.nih.gov
... Nestin (NM_006617), ngn3 (AF234829), Nkx6.1 (NM_006168), NRSF/REST (U13879), Olig2 ...
Expression of Pax4 in embryonic stem cells promotes differentiation of Nestin ...
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The Cooperation Between Two Silencers Creates an Enhancer Element that Controls Both the Lens- …
RPH Dirks, HJ Kraft, ST Genesen, EJ Klok, R Pfundt … - European Journal of Biochemistry, 1996 - blackwell-synergy.com
... Second, the Ncol fragment containing the rest of the first intron, the first exon
and approximately 750 bp of upstream sequences, was cloned in front of the 250 ...
Cited by 5 - Web Search - content.febsjournal.org - ejbiochem.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Effects of nonlinear damping in flexible space structures
A Hu, L TAYLOR - AIAA Guidance, Navigation and Control Conference, …, 1988 - pdf.aiaa.org
Page 1. EFFECTS OF NONLINEAR DAMPING IN FLEXIBLE SPACE STRUCTURES * Anren Hu
Dynacs Engineering Corporation Clearwater Florida * * Lawrence ...
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Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells
Y Hori, X Gu, X Xie, SK Kim - PLoS Med - dx.doi.org
... myosin light chain-2 (X57542), Nestin (NM_006617), ngn3 (AF234829), Nkx6.1 (NM_006168),
NRSF/REST (U13879), Olig2 ... (2003) Expression of Pax4 in embryonic stem ...
Cited by 1 - Web Search - medicine.plosjournals.org - plme.allenpress.com - plosmedicine.org - all 7 versions » - Get it from MIT Libraries

In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells - Full text - MIT Libraries
T Leon-Quinto, J Jones, A Skoudy, M Burcin, B … - Diabetologia, 2004 - springerlink.com
... using 4 mol/l HCl. The rest of the protocol is a standard immunocytochemistry
protocol, described below. Mouse anti-BrdU antibody ...
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Special Class of Nonlinear Damping Models in Flexible Space Structures
LW Taylor - pdf.aiaa.org
Page 1. VOL. 14, NO. 1, JAN.-FEB. 1991 J. GUIDANCE 77 Special Class of
Nonlinear Damping Models in Flexible Space Structures Anren ...
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Deciphering Regulatory Patterns of Inflammatory Gene Expression From Interleukin-1—Stimulated … - Full text - MIT Libraries
H Mayer, M Bilban, V Kurtev, F Gruber, O Wagner, … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 - atvbaha.org
... more or less staying at a constant level throughout the rest of the ... yielded several
combinations of known TFBSs, involving AP2, FOXD3, FREAC7, HFH3, and PAX4. ...
Cited by 1 - Cached - Web Search - atvb.ahajournals.org - homepage.univie.ac.at - ncbi.nlm.nih.gov - all 10 versions »

Missense Mutations of Human Homeoboxes: A Review - Full text - MIT Libraries
G Damante - HUMAN MUTATION, 2001 - doi.wiley.com
... is more easily affected by single amino acids changes than the rest of the ... Only a
fraction of PAX proteins have a functional HD (PAX3, PAX4, PAX6, PAX7); in ...
Web Search - doi.wiley.com - geocities.com

Gene regulatory factors in pancreatic development - Full text - MIT Libraries
J Jensen - Developmental Dynamics, 2004 - doi.wiley.com
... neurogenin3 (atoh5) fol- lowed by several genes that may be common between endocrine
cells (eg, Pax6, Isl1, NeuroD), or cell-specific (eg, Pax4, Brn4), among ...
Cited by 14 - Web Search - pi.be - ncbi.nlm.nih.gov

Stimulation of pancreatic islet neogenesis: a possible treatment for type 1 and type 2 diabetes.
A Vinik, L Rosenberg, GL Pittenger, D Taylor- … - Current Opinion in Endocrinology & Diabetes, 2004 - co-endocrinology.com
... adult human duct cells induce gene or protein expression of BETA2/NeuroD, Pax4,
Nkx 2.2 ... islet 96% of the time and spread throughput the pancreas the rest of the ...
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MPIbpc News
YS Chang, K Chowdhury, J Glaubitz, F Kirsch, V … - mpibpc.gwdg.de
Page 1. Max-Planck-Institut für biophysikalische Chemie MPIbpc News 8.
Jahrgang Göttingen Ausgabe Nr. 4 April 2002 The mammalian ...
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Retinoic acid increases the length and volume density of ducts in the rat embryonic pancreas - Full text - MIT Libraries
C Erasmus, C Penny, B Kramer - Development Growth and Differentiation, 2003 - dx.doi.org
... the formula (Vv) = Pd/Pt 100 where Pd is the number of points counted inside the
duct lumen and Pt is the total number of points counted over the rest of the ...
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Boolean feature discovery in empirical learning
G Pagallo, D Haussler - Machine Learning, 1990 - springerlink.com
Page 1. Machine Learning, 5, 71-99 (1990) © 1990 Kluwer Academic Publishers.
Manufactured in The Netherlands. Boolean Feature Discovery in Empirical Learning ...
Cited by 214 - Web Search - kluweronline.com - ingentaconnect.com - portal.acm.org - all 7 versions »

Genetic Association, Post-translational Modification and Protein-protein Interactions in Type 2 …
R Title - mcponline.org
... with the disease qualify, as rare variants while the rest are common variants.
Based on this, we propose that T2DM fits a mosaic model (Fig. ...
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Recent advances in the genetics of maturity-onset diabetes of the young and other forms of autosomal …
A Doria, N Plengvidhya - Curr Opin Endocrinol Diabetes, 2000 - co-endocrinology.com
... 2) [45]. About 60 to 70% of mutation carriers are diagnosed with diabetes
before age 25, the rest between ages 25 and 60. A small ...
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Identification of Domains Mediating Transcription Activation, Repression, and Inhibition in the …
RA Norris, MJ Kern - DNA and Cell Biology, 2001 - dx.doi.org
... demonstrate that the carboxy tail of the Prx2 protein functions as a mask, or
inhibition domain, hiding transcriptionactivation domains within the rest of the ...
Cited by 14 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Six3-mediated auto repression and eye development requires its interaction with members of the … - Full text - MIT Libraries
CC Zhu, MA Dyer, M Uchikawa, H Kondoh, OV Lagutin, … - Development, 2002 - dev.biologists.org
... 2A). The specificity of the binding was corroborated by the failure of the unrelated
homeodomain protein Pax4 to bind to GST-Grg5 (data not shown). ...
Cited by 29 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Lens crystallins of invertebrates
SI IUMAREV - Eur. J. Biochem, 1996 - blackwell-synergy.com
... The siinilar rccquiremetit of Pax4 (and possibly other cotnmon transcription factors)
for eye development as well as thc diversity, taxon-specificity and ...
Cited by 38 - Web Search - content.febsjournal.org - ejbiochem.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

[BOOK] Maternal uniparental disomy of human chromosome 7
K Hannula - 2001 - ethesis.helsinki.fi
... catalog number p short arm of chromosome PAGE polyacrylamide gel electrophoresis
pat paternal patUPD7 paternal uniparental disomy of chromosome 7 PAX4 gene for ...
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Expression and misexpression of members of the FGF and TGF families of growth factors in the … - Full text - MIT Libraries
DS Dichmann, CP Miller, J Jensen, RS Heller, P … - Dev Dyn, 2003 - doi.wiley.com
... FGFR3b was barely detectable at E12 but in- creased 10-fold during the following
2 days and reached a plateau at which it remained during the rest of gestation ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov

23rd Workshop of the Study Group on Artificial Insulin Delivery, Pancreas and Islet Transplantation … - Full text - MIT Libraries
E Board - Acta Diabetol, 2003 - springerlink.com
... Carbohydrate rich meals, exercise on ergometer, bed rest and reference measurements
were accomplished in a strict time schedule. Results Values of the sc. ...
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Electrophysiological characterization of insulin secreting β-cells in pancreatic tissue slices
PD Thesis - webdoc.sub.gwdg.de
Page 1. Electrophysiological characterization of insulin secreting β-cells
in pancreatic tissue slices PhD Thesis in partial fulfilment ...
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BMC Genomics - Full text - MIT Libraries
S Nelander, E Larsson, E Kristiansson, R Maansson, … - BMC Genomics, 2005 - biomedcentral.com
Page 1. ...
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Abstracts of Papers Submitted to the American Pancreatic Association
S by a grant from Solvay, C Pharmaceutical, GA … - Pancreas, 2001 - pancreasjournal.com
November 2001, 23:4 > Abstracts of Papers Submitted to... < Previous |
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