Fusion genes in leukemia: an emerging network
SK Bohlander, FTC Alert - Cytogenet Cell Genet, 2000 - content.karger.com
... etc.), but also networks connecting several genes with more than one fusion partner
(eg ETV6/RUNX1 (AML1), RUNX1/CBFA2T1 (ETO), ETV6/EVI1, RUNX1/EVI1, ETV6/ABL ...
Cited by 13 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease … - Full text - MIT Libraries
A Barbouti, M Hoglund, B Johansson, C Lassen, PG … - Cancer Res, 2003 - cancerres.aacrjournals.org
... 2 , 3) . Possible clues behind CML progression are given by the occurrence of
AML-associated translocations/fusion genes, eg, t(3;21)(q26;q22)/RUNX1-EVI1, t(7 ...
Cited by 8 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - lu-research.lub.lu.se - all 5 versions »

Progress in Hematology
T Yamagata, K Maki, K Mitani - Int J Hematol, 2005 - cardenjennings.metapress.com
... has been identified in leukemia-associated chromosomal translocations, including
t(8;21) (Runx1-ETO/MTG8), t(16;21) (Runx1-MTG16), t(3;21) (Runx1-Evi1), t(12;21 ...
Web Search

Core binding factor genes and human leukemia - Full text - MIT Libraries
SM Hart, L Foroni - Haematologica, 2002 - haematologica.it
... Background. The core binding factor (CBF) transcription complex, consisting of the
interacting proteins RUNX1 and CBFβ, is essential for normal hematopoiesis. ...
Cited by 9 - View as HTML - Web Search - haematologica.org - ncbi.nlm.nih.gov - haematologica.org - all 8 versions »

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 … - Full text - MIT Libraries
ML Kalev-Zylinska, JA Horsfield, MV Flores, JH … - Development, 2002 - dev.biologists.org
... RUNX1 is involved in several other chromosomal translocations in acute leukemias,
of which TEL-RUNX1 in t(12;21) and RUNX1-EVI1 in t(3;21) are the most common ...
Cited by 30 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Prevalence estimates of recurrent balanced cytogenetic aberrations and gene fusions in unselected …
F Mitelman, F Mertens, B Johansson - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
Page 1. Prevalence Estimates of Recurrent Balanced Cytogenetic Aberrations and
Gene Fusions in Unselected Patients with Neoplastic Disorders ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Familial mutations of the transcription factor RUNX1 (AML1, CBFA2) predispose to acute myeloid …
P Ganly, LC Walker, CM Morris - Leuk Lymphoma, 2004 - dx.doi.org
... fusion genes, including ETV6-RUNX1 associated with the commonly recurring
t(12;21)(p13;q22) [11], RUNX1-EAP, RUNX1-MDS1 or RUNX1-EVI1 variously associated ...
Cited by 2 - Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

The runx genes: gain or loss of function in cancer - Full text - MIT Libraries
K Blyth, ER Cameron, JC Neil - Nature Reviews Cancer, 2005 - nature.com
... For exam- ple, RUNX1–ETO is particularly common in primary AML of the subtype M2,
whereas RUNX1–EVI1 and many of the less common translocations are found ...
Web Search - ncbi.nlm.nih.gov

A Novel Gene, FGA7, Is Fused to RUNX1/AML1 in a t (4; 21)(q28; q22) in a Patient With T-Cell Acute …
FM Mikhail, L Coignet, N Hatem, ZI Mourad, HM … - GENES, CHROMOSOMES & CANCER, 2004 - doi.wiley.com
... INTRODUCTION The AML1 gene (also known as RUNX1 or CBFA2), located in chromosome
band ... to the 3 region of a partner gene, including EAP, MDS1, EVI1, ETO, and ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34 cells, allowing nerve growth …
JC Mulloy, V Jankovic, M Wunderlich, R Delwel, J … - pnas.org
... is frequently affected by chromosomal translocations in acute leukemia, leading
to the formation of the AML1-ETO (RUNX1-CBFA2T1) [t(8;21)], RUNX1/MDS/EVI1 [t(3 ...
Web Search - dx.doi.org - dx.doi.org - pnas.org

PRDX4, a member of the peroxiredoxin family, is fused to AML (RUNX1) in an acute myeloid leukemia …
Y Zhang, N Emmanuel, G Kamboj, J Chen, M Shurafa, … - Genes, Chromosomes and Cancer, 2004 - doi.wiley.com
... The AML1 gene (also known as RUNX1) at 21q22 codes for core binding factor (CBF ... exon
6 were reported in t(3;21) involving AML1 and MDS1/EVI1 (Nucifora et al ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 … - Full text - MIT Libraries
H Yuasa, Y Oike, A Iwama, I Nishikata, D Sugiyama, … - EMBO J, 2005 - embojournal.npgjournals.com
... OP9 cocultures prevents the defective vascular remodeling in Runx1 homozygous mutant ...
its cognate receptor, Tie2, significantly decreased in Evi1 –/– embryos ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - embojournal.npgjournals.com - ncbi.nlm.nih.gov

Analysis of the interaction of TIP60β and PIN1 with the ets family transcription factor ETV6
CD Zhang - edoc.ub.uni-muenchen.de
... SYK, and FGFR3, to transcription factors, such as AML1/RUNX1, EVI1, HLXB9, MN1
or PAX5, to genes of various or unknown functions, such as ...
View as HTML - Web Search

Phosphorylation of AML1/RUNX1 Regulates Its Degradation and Nuclear Matrix Association - Full text - MIT Libraries
JR Biggs, Y Zhang, LF Peterson, M Garcia, DE Zhang … - Molecular Cancer Research, 2005 - mcr.aacrjournals.org
... The importance of acute myeloid leukemia 1 (AML1; RUNX1) to normal hematopoietic ...
disruption of AML1 secondary to translocations (AML/ETO, AML/EVI1, and TEL/AML ...
Web Search - mcr.aacrjournals.org

Consistent Intergenic Splicing and Production of Multiple Transcripts Between AML1 at 21q22 and … - Full text - MIT Libraries
G Nucifora, CR Begy, H Kobayashi, D Roulston, D … - Proceedings of the National Academy of Sciences - pnas.org
... Imayoshi, N. Asou, T. Nakamura, and K. Morishita A novel EVI1 gene family ... Bushweller,
and NA Speck Energetic Contribution of Residues in the Runx1 Runt Domain ...
Cited by 100 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA … - Full text - MIT Libraries
M Niki, H Okada, H Takano, J Kuno, K Tani, H … - Proc Natl Acad Sci USA, 1997 - dx.doi.org
... Wee, T. Yokomizo, and Y. Ito Dimerization with PEBP2{beta} protects RUNX1/AML1 from ...
page GM Cuenco, G. Nucifora, and R. Ren Human AML1/MDS1/EVI1 fusion protein ...
Cited by 95 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Oligo GEArray® Human TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... signaling of TGF-β superfamily: BAMBI, BMPER, CDKN2B, CER1, CHRD, CST3, ENG, EVI1,
FKBP1B, FST, GREM1, HIPK2, MAP3K7, NBL1, NOG, PLAU, RUNX1, RUNX2, SMURF1 ...
View as HTML - Web Search

Oligo GEArray® Mouse TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... regulating signaling of TGF-β superfamily: Bambi, Bmper, Cdkn2b, Cer1, Chrd, Eng,
Evi1, Fkbp1b, Fst, Grem1, Lap3, Ltbp4, Nbl1, Nog, Runx1, Runx2, Smurf1 ...
View as HTML - Web Search

Oligo GEArray® Rat TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... TGF-β superfamily: Bambi, Cdkn2b, Chrd, Cktsf1b1, Cst3, Eng, Evi1, Fkbp1b, Fmod,
Fnta, Fst, Glmn, Hipk2, Lap3, Ltbp4, Map3k7, Nbl1, Nog, Runx1, Runx2, Smurf1 ...
View as HTML - Web Search

Diagnostic value of fluorescence in situ hybridization for the detection of genomic aberrations in … - Full text - MIT Libraries
S Froehling, S Kayser, C Mayer, S Miller, C … - Haematologica, 2005 - haematologica.org
... reference inv(3)/t(3;3) 858_c_9/14EE12 3q26 EVI1, D3S1212 CEPH/ICI
t(8;21) 464_h_8/72_h_9 21q22 RUNX1 CEPH +P1 164 8q22 CBFA2T1 t ...
View as HTML - Web Search - ncbi.nlm.nih.gov

The acetyltransferase Tip60 interacts with TEL/ETV6 and functions as a transcriptional co-repressor
I NORDENTOFT, P JOeRGENSEN - biochemj.org
... JAK2(9p24) [31], TRKC(15q24) [9] and transcription factors: AML1/RUNX1(21q22)
[2;17;41] EVI1(3q26) [39], and CDX2(13q12) [8]. TEL contains two functional ...
View as HTML - Web Search

t (8; 21) Breakpoints on Chromosome 21 in Acute Myeloid Leukemia are Clustered within a Limited … - Full text - MIT Libraries
H Miyoshi, K Shimizu, T Kozu, N Maseki, Y Kaneko, … - Proceedings of the National Academy of Sciences - pnas.org
... MM Le Beau, RA Larson, and JD Rowley Genomic DNA breakpoints in AML1/RUNX1 and ETO ...
page GM Cuenco, G. Nucifora, and R. Ren Human AML1/MDS1/EVI1 fusion protein ...
Cited by 241 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Translocation Breakpoints in Cancer
AM Oliveira, JA Fletcher - ehgonline.net
... syndrome 1 (MDS1) in myelodysplastic (preleukemic) syndromes, RUNX1±ecotropic viral
integration site 1 (EVI1) in chronic myelogenous leukemia in blast crisis ...
View as HTML - Web Search

Analysis of ETV 6/RUNX 1 fusions for evaluating the late effects of cancer therapy in ALL(acute … - Full text - MIT Libraries
MS Brassesco, ML Camparoto, LG Tone, ET Sakamoto- … - Cytogenetic and Genome Research, 2004 - content.karger.com
... Translocations involving the RUNX1 gene have been identified in therapy-related ... balanced
translocations with ETO (Eight Twenty One) and EVI1 (Ecotropic Viral ...
Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

The leukemic fusion gene AML 1-MDS 1-EVI 1 suppresses CEBPA in acute myeloid leukemia by activation … - Full text - MIT Libraries
D Helbling, BU Mueller, NA Timchenko, A Hagemeijer … - Proceedings of the National Academy of Sciences - pnas.org
... with chronic myeloid leukemia in blast crisis (CML-BC) (3-5). AME is an in-frame
fusion of the AML1 and MDS1/EVI1 genes (6). AML1 (also known as RUNX1) is one ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia … - Full text - MIT Libraries
T Yoshida, H Kanegane, M Osato, M Yanagida, T … - Am J Hum Genet, 2002 - journals.uchicago.edu
... truncated artificially or is replaced with foreign sequences, as seen in
leukemia-associated chimeric products of RUNX1 such as AML1-ETO and AML1-Evi1, or ...
Cited by 13 - Web Search - journals.uchicago.edu - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the … - Full text - MIT Libraries
M Stewart, N MacKay, ER Cameron, JC Neil - J. Virol, 2002 - jvi.asm.org
... that they are separated by a large distance, 160, 90, and 30 kb for RUNX1, RUNX2,
and ... and Cb1/Fim3 loci, which appear to activate the c-Myc and Evi1 genes from ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

A unique AML1 (CBF2A) rearrangement, t (1; 21)(p32; q22), observed in a patient with acute … - Full text - MIT Libraries
AM Cherry, CD Bangs, P Jones, S Hall, Y Natkunam - Cancer Genet. Cytogenet, 2001 - ncbi.nlm.nih.gov
... q26;q22) or AML1 fusion with one of three genes, MDS1, EAP or EVI1, in therapy ... Runx1
protein; Transcription Factors. PMID: 11566347 [PubMed - indexed for MEDLINE ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Core-binding factors in haematopoiesis and leukaemia - Full text - MIT Libraries
NA Speck, DG Gilliland - Nature Reviews Cancer, 2002 - nature.com
... 12. Huang, G. et al. Dimerization with PEBP2 protects RUNX1/AML1 from
ubiquitin-proteosome-mediated degradation. EMBO J. 20, 723-733 (2001). ...
Cited by 60 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size HS-023-2/HS-023N-2 …
FG Grouping - tebu-bio.com
... CER1 (cerberus), CHRD (chordin), CKTSF1B1 (gremlin), ENG (endoglin), EVI1 (Evi-1),
FKBP1B, FST (follistatin), NBL1 (DAN), NMA, PLAU (uPA), RUNX1 (AML1), RUNX2 ...
View as HTML - Web Search

Molecular mechanism of blastic crisis in chronic myelocytic leukemia.
K Mitani - Leukemia, 1997 - ncbi.nlm.nih.gov
... Substances: Chimeric Proteins; DNA-Binding Proteins; EVI1 protein, human; Neoplasm
Proteins; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Runx1 protein ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array: AR-SAMM-023
FG Grouping - eurogentec.be
... Chrd (chordin), Cktsf1b1 (gremlin), Eng (endoglin), Evi1 (Evi-1), Fkbp1b, Fst
(follistatin), Lap3 (Lano), Nbl1 (DAN), Nog (noggin), Runx1 (AML1), Runx2 ...
View as HTML - Web Search - eurogentec.com

Transcription Factors: Normal and Malignant Development of Blood Cells
IJ Hematol - Int J Hematol, 2001 - cardenjennings.metapress.com
... Two, which focuses on myeloid differentiation,consists of the topics RUNX1(AML1)/
CBFB ... targets nine factors: retinoic acid receptor (RAR) , inv(16), EVI1, t(8;21 ...
Web Search

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array: AR-SAHS-023
FG Grouping - eurogentec.com
... CER1 (cerberus), CHRD (chordin), CKTSF1B1 (gremlin), ENG (endoglin), EVI1 (Evi-1),
FKBP1B, FST (follistatin), NBL1 (DAN), NMA, PLAU (uPA), RUNX1 (AML1), RUNX2 ...
View as HTML - Web Search - eurogentec.be

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size MM-023-2/MM-023N-2 …
FG Grouping - tebu-bio.com
... Chrd (chordin), Cktsf1b1 (gremlin), Eng (endoglin), Evi1 (Evi-1), Fkbp1b, Fst
(follistatin), Lap3 (Lano), Nbl1 (DAN), Nog (noggin), Runx1 (AML1), Runx2 ...
View as HTML - Web Search

AML1-FOG2 fusion protein in myelodysplasia - Full text - MIT Libraries
EM Chan, EM Comer, FC Brown, KE Richkind, ML … - Blood, 2005 - bloodjournal.org
... Requirement of Runx1/AML1/PEBP2alphaB for the generation of haematopoietic cells ...
The leukemia-associated transcription repressor AML1/MDS1/EVI1 requires CtBP ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

GEArray S Series Mouse Autoimmune and Inflammatory Response Gene Array: AR-SAMM-602.3
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.com
... Camk2b, Camk4, Cdc25a, Cdkn1a, Cdkn2b, Chuk, Csnk2a1, Csnk2b, Eng, Evi1, Gsk3a-Rik ...
Nfkbib, Nfkbie, Nfkbil1, P300-ESTs, Raf1, Rel, Rela, Relb, Runx1, Runx2, Sp1 ...
View as HTML - Web Search - eurogentec.be

GEArray S Series Human Autoimmune and Inflammatory Response Gene Array: AR-SAHS-602
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.be
... CAMK2B, CAMK4, CDC25A, CDKN1A, CDKN2B, CHUK, CSNK2A1, CSNK2B, ENG, EVI1, GSK3A,
GSK3B ... NFKBIE, NFKBIL1, NFKBIL2, NFRKB, RAF1, REL, RELA, RELB, RUNX1, RUNX2, SP1 ...
View as HTML - Web Search - eurogentec.com

Multicolor karyotyping in acute myeloid leukemia
J Tchinda, S Volpert, N McNeil, T NEUMANN, I … - Leuk Lymphoma, 2003 - taylorandfrancis.metapress.com
... aberrations involving new translocation partners of RUNX1, at(3;21)(p13 or
p?25;q22) and at(7;21)(p22;q22), as well as one translocation involving EVI1, t( ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Multicolor Karyotyping in Acute Myeloid Leukemia
J TCHINDA, S VOLPERT, N McNEIL, T NEUMANN, I … - Leukemia & Lymphoma, 2003 - dx.doi.org
... aberrations involving new translocation partners of RUNX1, at(3;21)(p13 or
p?25;q22) and at(7;21)(p22;q22), as well as one translocation involving EVI1, t( ...
Web Search

Fusion of the TEL Gene on 12p13 to the AML1 Gene on 21q22 in Acute Lymphoblastic Leukemia - Full text - MIT Libraries
TR Golub, GF Barker, SK Bohlander, SW Hiebert, DC … - Proceedings of the National Academy of Sciences, 1995 - pnas.org
... MM Le Beau, RA Larson, and JD Rowley Genomic DNA breakpoints in AML1/RUNX1 and ETO ...
page GM Cuenco, G. Nucifora, and R. Ren Human AML1/MDS1/EVI1 fusion protein ...
Cited by 349 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TEL/AML1 Overcomes Drug Resistance Through Transcriptional Repression of Multidrug Resistance-1 Gene … - Full text - MIT Libraries
K Asakura, H Uchida, H Miyachi, H Kobayashi, Y … - Molecular Cancer Research, 2004 - mcr.aacrjournals.org
... AML1 (also known as Runx1) is a transcription factor, which is essential for the
development ... ETO [t(8;21)(q22;q22)], CBFß/MYH11 [inv(16)], and AML1/EVI1 [t(3 ...
Cited by 1 - Web Search - mcr.aacrjournals.org - ncbi.nlm.nih.gov

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor … - Full text - MIT Libraries
P Hematti, BK Hong, C Ferguson, R Adler, H Hanawa, … - PLoS Biol, 2004 - dx.doi.org
... be involved in oncogenic translocations: ARHGEF12, MDS1, MKL1, MSF, HMGA2, RAD51L1,
and RUNX1. ... second intron, 20–180 kb upstream of the first intron of EVI1. ...
Cited by 6 - Web Search - medicine.plosjournals.org - plme.allenpress.com - plosbiology.org - all 11 versions »

AML 1/RUNX 1 mutations are infrequent, but related to AML-M 0, acquired trisomy 21, and leukemic …
T Taketani, T Taki, J Takita, M Tsuchida, R Hanada … - Genes Chromosomes and Cancer, 2003 - doi.wiley.com
... The AML1/RUNX1 gene is located on chromo- some band 21q22 and is recognized as an ...
AML1-MTG8/ETO) (Miyoshi et al., 1991), t(3;21)(q26;q22) (AML1- EVI1/EAP/MDS1 ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Phorbol Ester Treatment of K 562 Cells Regulates the Transcriptional Activity of AML 1 c through … - Full text - MIT Libraries
Y Zhang, JR Biggs, AS Kraft - J Biol Chem, 2004 - jbc.org
... by the frequent disruption of AML1 secondary to translocations (AML/ETO, AML/EVI1,
and TEL/AML ... RUNX2/AML3 shares extensive sequence homology with RUNX1/AML1. ...
Cited by 1 - Web Search - jbc.org - ncbi.nlm.nih.gov

Point mutation in AML 1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects … - Full text - MIT Libraries
D Vradii, SK Zaidi, JB Lian, AJ van Wijnen, JL … - Proceedings of the National Academy of Sciences, 2005 - pnas.org
... This cell line expresses Runx1 (Fig. ... Our findings are reinforced by the induction
of FGF4 and EVI1, key regulators of cell transformation, in the MT cell line ...
Web Search - dx.doi.org - ncbi.nlm.nih.gov

Production of high-titer helper-free retroviruses by transient transfection - Full text - MIT Libraries
WS PEAR, GP NOLAN, ML SCOTT, D BALTIMORE - Proc. Nat. Acad. Sci, 1993 - pnas.org
... Immunoprecipitation Screen Reveals Protein Kinase C{beta} as a Direct RUNX1 Target
Gene J. Biol. ... N. Asou, T. Nakamura, and K. Morishita A novel EVI1 gene family ...
Cited by 1223 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 5 versions »

Focus on myeloproliferative diseases and myelodysplastic syndromes - Full text - MIT Libraries
RA Van Etten, KM Shannon - Cancer Cell, 2004 - tufts-mori.org
... Somatic RUNX1 mutations have also been reported recently in de novo and
therapy-induced MDS ... of t(11;16) in t-MDS (Lavau et al., 2000), and of EVI1, a zinc ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov

Stem cell expression of the AML 1/ETO fusion protein induces a myeloproliferative disorder in mice - Full text - MIT Libraries
TS Fenske, G Pengue, V Mathews, PT Hanson, SE Hamm … - Proceedings of the National Academy of Sciences - pnas.org
... Similarly, both Runx1 and Runx3 are critical for T cell development (29, 30). ... genes
associated with human leukemia (eg, PML/RAR and AML1/MDS1/EVI1) support the ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Drug therapy for acute myeloid leukemia - Full text - MIT Libraries
MS Tallman, DG Gilliland, JM Rowe - Blood, 2005 - bloodjournal.org
... Table 3 and may involve the hematopoietic transcription factors RUNX1, GATA-1 ... evidence
for overexpression of certain transcription factors such as EVI1 in AML ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov