Dimerization with PEBP2ss protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation - Full text - MIT Libraries
G Huang, K Shigesada, K Ito, HJ Wee, T Yokomizo, Y … - EMBO J, 2001 - embojournal.npgjournals.com
... with PEBP2ß protects RUNX1/AML1 from ubiquitin–proteasome-mediated degradation.
Gang Huang , Katsuya Shigesada 1 , Kosei Ito , Hee-Jun Wee , Tomomasa ...
Cited by 53 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 8 versions »

Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera - Full text - MIT Libraries
G Huang, K Shigesada, HJ Wee, PP Liu, M Osato, Y … - Blood, 2004 - dx.doi.org
... Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion
16 chimera. Gang Huang , Katsuya Shigesada , Hee-Jun Wee , P. Paul Liu ...
Cited by 2 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear … - Full text - MIT Libraries
MY Ahn, G Huang, SC Bae, HJ Wee, WY Kim, Y Ito - Mol. Cell. Biol, 2005 - dx.doi.org
... Mee-Young Ahn, Gang Huang, Suk-Chul Bae * , Hee-Jun Wee, Woo-Young Kim ... Cytoplasm
and Prevented from Functioning as a Partner of the Runx1 Transcription Factor ...
Cited by 4 - Web Search - pnas.org - pnas.org - pubmedcentral.nih.gov

The leukemia-associated AML1 (Runx1)–CBF beta complex functions as a DNA-induced molecular clamp - Full text - MIT Libraries
J Bravo, Z Li, NA Speck, AJ Warren - Nat. Struct. Biol, 2001 - nature.com
... sugar phosphate The leukemia-associated AML1 (Runx1)–CBFβ complex functions
as a DNA-induced molecular clamp Jerónimo Bravo ...
Cited by 39 - Web Search - nature.com - cs.dartmouth.edu - ncbi.nlm.nih.gov

Eukaryotic transcriptional regulatory complexes: cooperativity from near and afar - Full text - MIT Libraries
K Ogata, K Sato, T Tahirov, T Tahirov - Curr Opin Struct Biol, 2003 - cm.utexas.edu
... structures have revealed different modes of protein±protein interaction on the promoter
DNA from near (eg the Runx1±CBFb±DNA, NFAT±Fos±Jun±DNA, GABPa ...
Cited by 17 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

NCAM (CD56) and RUNX1 (AML1) Are Up-Regulated in Human Ischemic Cardiomyopathy and a Rat Model of … - Full text - MIT Libraries
H Tissue - American Journal of Pathology, 2003 - ajp.amjpathol.org
... to analyze NCAM expression in relation to c-JUN kinase activity. According to this
hypothesis, concomitant up-regula- tion of NCAM(CD56) and RUNX1(AML1) is not ...
Cited by 2 - Web Search - ajp.amjpathol.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

SHORT REPORT A novel inherited mutation of the transcription factor RUNX1 causes thrombocytopenia …
LC Walker, J Stevens, H Campbell, R Corbett, R … - blackwell-synergy.com
... Architecture and anatomy of the genomic locus encoding the human leukemia-associated
transcription factor RUNX1/AML1. ... Online publication date: 1 - Jun - 2004 . ...
Web Search

Oligo GEArray® Mouse TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Plat, Plau, Serpine1, Tdgf1, Tgfb3, Tgfbr1, Tgfbr3 Transcription Factors and Regulators:
Dlx2, Fos, Gsc, Idb1, Idb3, Jun, Junb, Myc, Nr0b1, Runx1, Runx2, Smad1 ...
View as HTML - Web Search

Jun Hirose A developing picture of Taku Kouro lymphopoiesis in bone marrow - Full text - MIT Libraries
H Igarashi, T Yokota, N Sakaguchi, PW Kincade - Immunological Reviews, 2002 - ingentaconnect.com
Page 1. Jun Hirose A developing picture of Taku Kouro lymphopoiesis in bone marrow
Hideya Igarashi Takafumi Yokota Nobuo Sakaguchi Paul W. Kincade ...
Web Search

AT Lymphocyte-Specific Transcription Complex Containing RUNX1 Activates MHC Class I Expression - Full text - MIT Libraries
TK Howcroft, JD Weissman, A Gegonne, DS Singer - The Journal of Immunology, 2005 - jimmunol.org
... AT Lymphocyte-Specific Transcription Complex Containing RUNX1 Activates MHC Class
I Expression. ... The mutant RUNX1 protein, L148D, does not bind DNA. ...
Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Oligo GEArray® Rat TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... Transcription Factors and Regulators: Dlx2, Fos, Gsc, Idb1, Idb3, Jun, Junb, Madh1,
Madh3, Madh4, Madh5, Madh7, Madh9, Myc, Nr0b1, Runx1, Runx2, Sox4, Stat1 ...
View as HTML - Web Search

Oligo GEArray® Human TGFβ BMP Signaling Pathway Microarray
S Conditions - search.cosmobio.co.jp
... INHBB, INHBC, PDGFB, PLAU, SERPINE1 Transcription Factors and Regulators: DLX2,
EVI1, FOS, GSC, HIPK2, ID1, ID3, ID4, JUN, JUNB, MYC, NR0B1, RUNX1, RUNX2, SMAD1 ...
View as HTML - Web Search

Translocation t (12; 21) is related to in vitro cellular drug sensitivity to doxorubicin and … - Full text - MIT Libraries
BM Frost, E Forestier, G Gustafsson, P Nygren, M … - Blood, 2004 - ncbi.nlm.nih.gov
2004 Oct 15;104(8):2452-7. Epub 2004 Jun 24. ... britt-marie.frost@kbh.uu.se The
t(12;21) (p13;q22) translocation resulting in ETV6/RUNX1 (previously named TEL/AML1 ...
Cited by 1 - Web Search

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34 cells, allowing nerve growth …
JC Mulloy, V Jankovic, M Wunderlich, R Delwel, J … - pnas.org
... ETO (RUNX1-CBFA2T1) [t(8;21)], RUNX1/MDS/EVI1 [t(3;21)], ETV6-RUNX1 [t(12;21 ... activator
in certain cellular contexts, perhaps by up-regulating c-JUN activity (22 ...
Web Search - dx.doi.org - dx.doi.org - pnas.org

Runt-related Gene 2 in Endothelial Cells - Full text - MIT Libraries
L Sun, M Vitolo, A Passaniti - Cancer Research, 2001 - cancerres.aacrjournals.org
... appears to be restricted to ECs (21 , 22) , others, such as fos/jun (23) , nuclear ...
2 is a member of the mammalian RUNX family, which also includes RUNX1/Cbf 2 ...
Cited by 13 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila … - Full text - MIT Libraries
E Ogawa, M Maruyama, H Kagoshima, M Inuzuka, J Lu, … - Proceedings of the National Academy of Sciences - pnas.org
... for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1
transgene ... of the Activator Protein-1 Factors c-Fos and c-Jun with Cbfa1 for ...
Cited by 272 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A RUNX2/PEBP2 alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in … - Full text - MIT Libraries
YW Zhang, N Yasui, K Ito, G Huang, M Fujii, J … - Cancer Res, 2005 - dx.doi.org
... Wen Zhang * , , Natsuo Yasui , Kosei Ito * , Gang Huang * , Makiko Fujii § ,
Jun-ichi Hanai ... and Y. Ito Dimerization with PEBP2{beta} protects RUNX1/AML1 from ...
Cited by 88 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size HS-023-2/HS-023N-2 …
FG Grouping - tebu-bio.com
... EVI1 (Evi-1), FKBP1B, FST (follistatin), NBL1 (DAN), NMA, PLAU (uPA), RUNX1 (AML1),
RUNX2 ... convergence of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187 (3 ...
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Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among …
A Andersson, P Eden, D Lindgren, J Nilsson, C … - Leukemia, 2005 - ncbi.nlm.nih.gov
2005 Jun;19(6):1042-50. ... of 40 cell lines as well as of primary leukemias harboring
11q23/MLL rearrangements, t(1;19)[TCF3/PBX1], t(12;21)[ETV6/RUNX1], t(8;21 ...
Web Search - nature.com - nature.com - Get it from MIT Libraries

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array Cat. No.* Kit Size MM-023-2/MM-023N-2 …
FG Grouping - tebu-bio.com
... 1), Fkbp1b, Fst (follistatin), Lap3 (Lano), Nbl1 (DAN), Nog (noggin), Runx1 (AML1),
Runx2 ... convergence of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187 (3 ...
View as HTML - Web Search

ETV6: a versatile player in leukemogenesis. - Full text - MIT Libraries
SK Bohlander - Semin Cancer Biol, 2005 - ncbi.nlm.nih.gov
2005 Jun;15(3):162-74. ... sbohlan@gwdg.de Alterations of the ets family transcription
factor ETV6 (TEL) and the RUNT domain transcription factor RUNX1 (AML1) play ...
Web Search

The G/G Genotype of a Resistin Single-Nucleotide Polymorphism at-420 Increases Type 2 Diabetes … - Full text - MIT Libraries
H Osawa, K Yamada, H Onuma, A Murakami, M Ochi, H … - The American Journal of Human Genetics, 2004 - journals.uchicago.edu
... 1 Mitsuru Hashiramoto, 1 Azuma Kanatsuka, 4 Yasuhisa Fujii, 2 Jun Ohashi, 6 ... and in
the gene encoding Runt-related transcription factor 1 (RUNX1) for rheumatoid ...
Cited by 4 - Web Search - fukui-med.ac.jp - ncbi.nlm.nih.gov

Mutations of the PU. 1 Ets domain are specifically associated with murine radiation-induced, but not … - Full text - MIT Libraries
N Suraweera, E Meijne, J Moody, LG Carvajal- … - Oncogene, 2005 - nature.com
... proteins including GATA1 binding protein 1 (GATA1), CCAAT/enhancer binding protein
beta (CEBPB), and other myeloid regulators such as c-jun and RUNX1/AML-1 ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov

GEArray Q Series Mouse TGFβ BMP Signaling Pathway Gene Array: AR-SAMM-023
FG Grouping - eurogentec.be
... noggin), Runx1 (AML1), Runx2 References 1. Miyazono K, Kusanagi K, Inoue H., Divergence
and convergence of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; 187 ...
View as HTML - Web Search - eurogentec.com

GEArray Q Series Human TGFβ BMP Signaling Pathway Gene Array: AR-SAHS-023
FG Grouping - eurogentec.com
... uPA), RUNX1 (AML1), RUNX2, TDGF1 References 1. Miyazono K, Kusanagi K, Inoue H.,
Divergence and convergence of TGF-beta/BMP signaling, J Cell Physiol 2001 Jun; ...
View as HTML - Web Search - eurogentec.be

Upstream and downstream targets of RUNX proteins - Full text - MIT Libraries
F Otto, M Luebbert, M Stock - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... RUNX protein that regulates osteocalcin expression, the earlier experiments involving
RUNX1 point to ... the activator protein-1 factors c-Fos and c-Jun with Cbfa1 ...
Cited by 16 - Web Search - ncbi.nlm.nih.gov

Gene expression and viral prodution in latently infected, resting CD4 T cells in viremic versus … - Full text - MIT Libraries
TW Chun, JS Justement, RA Lempicki, J Yang, G … - Proc. Natl. Acad. Sci. USA, 2003 - pnas.org
... Tae-Wook Chun* † , J. Shawn Justement*, Richard A. Lempicki ‡ , Jun Yang ‡ , Glynn
Dennis, Jr. ‡ , Claire W. Hallahan*, ... (CMYB, YY1, TFCP2 and RUNX1). ...
Cited by 24 - Web Search - david.niaid.nih.gov - apps1.niaid.nih.gov - dx.doi.org - all 8 versions »

Establishment and characterization of a stable cell line to evaluate cellular Runx 2 activity - Full text - MIT Libraries
HJ Kim, HD Park, JH Kim, JY Cho, JY Choi, JK Kim, … - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... but was increased to the highest by Runx2 (about 10 folds) while Runx1 and Runx3 ...
activation of the 6xOSE2-luc reporter gene, c-fos and c-jun, components of ...
Web Search - ncbi.nlm.nih.gov

Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2
J Snaddon, ML Smith, M Neat, M Cambal-Parrales, A … - Genes Chromosomes Cancer, 2003 - doi.wiley.com
... For example, RUNX1 mutations have been reported in cases of both AML and
myelodysplastic ... regions of C/EBP, GCN4, and the proteins of the myc, jun, and fos ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Cbfβ interacts with Runx 2 and has a critical role in bone development - Full text - MIT Libraries
M Kundu, A Javed, JP Jeon, A Horner, L Shum, M … - Nature Genetics, 2002 - nature.com
... Co-immunoprecipitation assays showed that Cbfβ and Cbfβ–GFP could interact with
Runx1 (Fig. ... including Smads, C/EBP, Msx2, Groucho and c-Fos/c-Jun 19–23 . ...
Cited by 42 - Web Search - nature.com - cellbio.wustl.edu - ncbi.nlm.nih.gov - all 5 versions »

A Literature Based Method for Identifying Gene-Disease Connections
LA Adamic, D Wilkinson, BA Huberman, E Ada - CSB, 2002 - dx.doi.org
... Focusing on “acute myeloid leukemia” (AML), consider for example the gene
RUNX1, which our measure shows to be most tied to AML. ...
Cited by 12 - Web Search - ieeexplore.ieee.org - doi.ieeecomputersociety.org - doi.ieeecs.org - all 10 versions »

Progress in Hematology
T Yamagata, K Maki, K Mitani - Int J Hematol, 2005 - cardenjennings.metapress.com
... However, in some cases, Runx1- ETO has been reported to enhance the expression
of genes such as C/EBP , c-Jun, and TRKA [27-29]. ...
Web Search

Genomic organization of the mouse peroxisome proliferator-activated receptor beta/delta gene: … - Full text - MIT Libraries
LK Larsen, EZ Amri, S Mandrup, C Pacot, K … - Biochem. J, 2002 - biochemj.org
... encoding AML1/RUNX1, we performed a series of experiments to investigate if the
5’-UTR Biochemical Journal Immediate Publication. Published on 12 Jun 2002 as ...
Cited by 8 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors - Full text - MIT Libraries
ATLSTC Containing, RAMHCCI Expression - Biochemistry, 1998 - dx.doi.org
... Home page, Mol Cancer Res Home page JR Biggs, Y. Zhang, LF Peterson, M. Garcia,
DE Zhang, and AS Kraft Phosphorylation of AML1/RUNX1 Regulates Its Degradation ...
Web Search - pnas.org

Respiratory Research - Full text - MIT Libraries
EA Renzoni, DJ Abraham, S Howat, X Shi-Wen, P … - Respiratory Research, 2004 - eprints.kcl.ac.uk
... JUNB 2049_s_at 3.7 4.2 jun B proto-oncogene JUNB 32786_at 4.4 3.0 jun B proto ... 2 NRIP1
40088_at 2.3 1.8 nuclear receptor interacting protein 1 RUNX1 393_s_at 2.3 ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de

Using a Customized DNA Microarray for Expression Profiling of the Estrogen-Responsive Genes to … - Full text - MIT Libraries
S Terasaka, Y Aita, A Inoue, S Hayashi, M … - Environmental Health Perspectives, 2004 - earthscape.org
... associated proteins 5.1 FOS-like antigen 2 (FRA2) 3.0 v-jun avian sarcoma virus
17 oncogene homolog (JUN) 7.5 c-fos (FOS) 14.4 AML1b (RUNX1) Tumor-associated ...
Cited by 3 - View as HTML - Web Search - ehis.niehs.nih.gov - dx.doi.org - csa.com - all 7 versions »

Molecular Mechanisms of Megakaryocyte Differentiation - Full text - MIT Libraries
H Schulze, RA Shivdasani - Seminars in Thrombosis and Hemostasis, 2004 - thieme-connect.com
... c-Jun is a JNK-independent coactivator of the PU.1 transcription factor. ... RUNX1 and
GATA-1 coexpression and cooperation in megakaryocytic differentiation. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Genetic evidence supporting selection of the valpha14i NKT cell lineage from double-positive … - Full text - MIT Libraries
T Egawa, G Eberl, I Taniuchi, K Benlagha, F … - Immunity, 2005 - ncbi.nlm.nih.gov
Immunity. 2005 Jun;22(6):705-16 ... Their development is absolutely dependent on Runx1
and RORgammat, transcription factors that influence, but are not required for ...
Web Search

Isolated recurrence of granulocytic sarcoma manifesting as extra-and intracranial masses--case …
S Nishimura, Y Kyuma, A Kamijo, A Maruta - Neurol Med Chir (Tokyo), 2004 - ncbi.nlm.nih.gov
Neurol Med Chir (Tokyo). 2004 Jun;44(6):311-6 ... Runx1 protein; Transcription Factors;
Cytarabine. PMID: 15253547 [PubMed - indexed for MEDLINE]
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In vitro hematopoietic differentiation of human embryonic stem cells induced by co-culture with … - Full text - MIT Libraries
J Wang, HP Zhao, G Lin, CQ Xie, DS Nie, QR Wang, … - Cell Biol Int, 2005 - ncbi.nlm.nih.gov
2005 Jun 8; [Epub ahead of print ... cells, and expressed hematopoietic genes such as
KDR, stem cell leukemia (scl) and runt-related transcription factor 1 (Runx1). ...
Web Search

CBFβ-SMMHC slows proliferation of primary murine and human myeloid progenitors
J D'Costa, S Chaudhuri, CI Civin, AD Friedman - Leukemia, 2005 - ncbi.nlm.nih.gov
Leukemia. 2005 Jun;19(6):921-9 ... USA. CBFbeta-SMMHC is expressed in 8% of
acute myeloid leukemias and inhibits AML1/RUNX1. In this ...
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Recent findings on genes associated with inflammatory disease.
R Yamada, K Ymamoto - ncbi.nlm.nih.gov
2005 Jun 3;573(1-2):136-51 ... diseases (cytotoxic T lymphocyte-associated 4 (CTLA4),
CARD15, DLG5, SLC22A4/A5, programmed cell death 1 (PDCD1), RUNX1, SLC9A3R1/NAT9 ...
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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors - Full text - MIT Libraries
F LOMBARDO, D KOMATSU, M HADJIARGYROU - Biochemistry, 1998 - pnas.org
... O. Brenner, G. Berke, D. Levanon, and Y. Groner Runx3 and Runx1 are required ... Physical
Interaction of the Activator Protein-1 Factors c-Fos and c-Jun with Cbfa1 ...
Web Search

Phorbol Ester Treatment of K 562 Cells Regulates the Transcriptional Activity of AML 1 c through … - Full text - MIT Libraries
Y Zhang, JR Biggs, AS Kraft - J Biol Chem, 2004 - jbc.org
... 2 The functional significance of RUNX1/AML1c amino-terminal phosphorylation therefore
remains ... of a number of transcription factors, including c-JUN and ETS. ...
Cited by 1 - Web Search - jbc.org - ncbi.nlm.nih.gov

GEArray S Series Mouse Autoimmune and Inflammatory Response Gene Array: AR-SAMM-602.3
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.com
... Elk3, Fkbp1b, Fos, Fosb, Fosl1, Fosl2, Gata3, Gata4, Icos, Irf1, Jun, Junb, Jund1 ...
Nfkbib, Nfkbie, Nfkbil1, P300-ESTs, Raf1, Rel, Rela, Relb, Runx1, Runx2, Sp1 ...
View as HTML - Web Search - eurogentec.be

GEArray S Series Human Autoimmune and Inflammatory Response Gene Array: AR-SAHS-602
FG Grouping, A Proteins, CS Receptors, ST Proteins … - eurogentec.be
... FOS, FOSL1, FOSL2, FOXP3, GATA3, GATA4, GRLF1, ICOS, IRF1, JUN, JUNB, JUND, MAF ... NFKBIB,
NFKBIE, NFKBIL1, NFKBIL2, NFRKB, RAF1, REL, RELA, RELB, RUNX1, RUNX2, SP1 ...
View as HTML - Web Search - eurogentec.com

A RUNX/AML-binding motif residing in a novel 13-bp DNA palindrome may determine the expression of … - Full text - MIT Libraries
E KOPF, R MISKIN - Journal of Thrombosis and Haemostasis - ingentaconnect.com
... Additionally, electrophoretic mobility shift assays have shown that the palindrome
could bind the RUNX1 component in nuclear extracts of myeloid cell lines ...
Web Search - ingentaconnect.com

Dysregulation of Chondrogenesis in Human Cleidocranial Dysplasia. - Full text - MIT Libraries
Q Zheng, E Sebald, G Zhou, Y Chen, W Wilcox, B Lee … - Am. J. Hum. Genet, 2005 - journals.uchicago.edu
... interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 ... EM, O'Keefe
RJ, Stein GS, Drissi MH (2005) Overlapping expression of Runx1(Cbfa2) and ...
Web Search - ncbi.nlm.nih.gov

Histone Deacetylase 3 Interacts with Runx 2 to Repress the Osteocalcin Promoter and Regulate … - Full text - MIT Libraries
TM Schroeder, RA Kahler, X Li, JJ Westendorf - J Biol Chem, 2004 - jbc.org
... of JNK and c-Jun relieve interactions between c-Jun- and HDAC3 ... and colleagues (83)
recently demonstrated that interactions between mSin3A and Runx1 (AML1) are ...
Cited by 3 - Web Search - jbc.org - ncbi.nlm.nih.gov

Cell cycle inhibition mediated by the outer surface of the C/EBP basic region is required but not … - Full text - MIT Libraries
Q Wang, R Cleaves, T Kummalue, C Nerlov, AD … - Oncogene, 2003 - nature.com
... upon known interaction domains for E2F, cdk2, cdk4, and c-Jun, we found ... or
downregulation of transcriptional regulators such as MyoD, c-Myb, AML1/Runx1, and ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov