Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis - Full text - MIT Libraries
Q Zhao, H Eberspaecher, V Lefebvre, B de … - Dev Dyn, 1997 - doi.wiley.com
... hindlimbs. Sox9 was expressed in the epiphyseal cartilage and in rest- ing
and proliferating chondrocytes of the growth plate (Fig. 6A ...
Cited by 93 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Sox9 and Nkx2. 5 determine the pyloric sphincter epithelium under the control of BMP signaling. - Full text - MIT Libraries
NA Theodosiou, CJ Tabin - Developmental Biology, 2005 - genetics.med.harvard.edu
... Keywords: Sox9; Nkx2.5; BMP signaling; Pyloric sphincter; Epithelial–mesenchymal
interactions ... or posterior stomach), which are absent from the rest of the ...
View as HTML - Web Search - ncbi.nlm.nih.gov

Hoxa-2 restricts the chondrogenic domain and inhibits bone formation during development of the … - Full text - MIT Libraries
B Kanzler, SJ Kuschert, YH Liu, M Mallo - Development, 1998 - dev.biologists.org
... 1I,J). The expression of Sox9 in this area was again complementary to that of
Hoxa-2: Sox9 was detected in the rest of the otic capsule, but not in the oval ...
Cited by 46 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Mammalian sex determination: joining pieces of the genetic puzzle - Full text - MIT Libraries
R Jimenez, M Burgos - BioEssays, 1998 - doi.wiley.com
... and this gene may then transactivate male pathway genes (MPGs), including SOX9,
AMH , and ... oocytes may be necessary to keep MPGs inactive during the rest of life ...
Cited by 5 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A major locus on mouse chromosome 18 controls XX sex reversal in Odd Sex(Ods) mice - Full text - MIT Libraries
Y Qin, C Poirier, C Truong, A Schumacher, AI … - Human Molecular Genetics, 2003 - hmg.oupjournals.org
... This is consistent with recent data showing that Sox9 can induce testis development
in ... XX Ods/+ mice developed as fully fertile females, the rest developing as ...
Cited by 5 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Sex Determination in Primates: the SRY Locus.
SM Thompson - bio.fsu.edu
... SOX9 predated the evolution of its potential activator, the SRY protein. ... from the
rest of the dataset and forms a natural outgroup. Combined with the inclusion ...
View as HTML - Web Search - csit.fsu.edu

Assembling a functional tympanic membrane: signals from the external acoustic meatus coordinate … - Full text - MIT Libraries
M Mallo, H Schrewe, JF Martin, EN Olson, S Ohnemus - Development, 2000 - dev.biologists.org
... present in the right relative position, irrespective of the morphology of the rest
of the ... the EAM is the source of an activity capable of inducing Sox9 in the ...
Cited by 5 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Regulation of Human COL9A1 Gene Expression - Full text - MIT Libraries
P Zhang, SA Jimenez, DG Stokes - J. Biol. Chem, 2003 - jbc.org
... This segment was also shown to interact with SOX9 and promote cartilage-specific ...
Van der Rest, M., Mayne, R., Ninomiya, Y., Seidah, NG, Chretien, M., and Olsen ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov

HMG box transcription factor geneHbp 1 is expressed in germ cells of the developing mouse testis - Full text - MIT Libraries
JM Smith, J Bowles, M Wilson, P Koopman - Developmental Dynamics, 2004 - doi.wiley.com
... Expression of Hbp1 in vitro leads to cell cycle ar- rest even in the ... Hprt (a
ubiquitously expressed gene in- cluded as a positive control), Sox9 (a Sertoli ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to … - Full text - MIT Libraries
S Grimmond, N Van Hateren, P Siggers, R Arkell, R … - Human Molecular Genetics, 2000 - hmg.oxfordjournals.org
... The rest of the embryo was used for Southern analysis in order to identify W e ... Sue
Morse for assistance with timed matings and Peter Koopman for the Sox9 probe ...
Cited by 38 - Web Search - hmg.oupjournals.org - hmg.oupjournals.org - ncbi.nlm.nih.gov - all 6 versions »

Searching for missing pieces of the sex-determination puzzle - Full text - MIT Libraries
M Bullejos, J Bowles, P Koopman - Journal of Experimental Zoology, 2001 - doi.wiley.com
... regulatory relationships have been elucidated (for example SF1 and SOX9 cooperate
to ... The success of this screening approach will rest on three main parameters ...
Cited by 5 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A broader perspective of sexual differentiation - Full text - MIT Libraries
M Fiddler, E Pergament - American Journal of Medical Genetics, 1997 - doi.wiley.com
... From a pheno- typic perspective, successful differentiation may rest on a threshold
of ... by mutations in and around the SRY-related gene, SOX9, on chromosome 17 ...
Cited by 4 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Sex and Molecular Biology
PN GOODFELLOW - oup.co.uk
... Both hypotheses are correct: about 85 per cent of XX males have Y chromosome sequences
in their genomes and the rest have mutations ... SRY, SOX9, and more genes ...
Web Search

Sex-determining genes in mice: building pathways
R Lovell-Badge, C Canning, R Sekido - Novartis Found Symp, 2002 - doi.wiley.com
... It then becomes important to establish whether SRY directly regulates Sox9 and if
so ... compared there is no homology outside the box, including the rest of the 10 ...
Cited by 16 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Effect of Bone Morphogenetic Protein-2 on Rat Intervertebral Disc Cells in Vitro
DC Isolation, PP Assay, RTPC Reaction, QRTPC … - Spine, 2003 - spinejournal.com
... Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Dev Dyn
1997; 209: 377-86. [Context Link]. 44. Bruckner P, van der Rest M. Structure ...
Cited by 6 - Web Search - spinejournal.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Screening of the 1 Mb SOX 9 5' control region by array CGH identifies a large deletion in a case of … - Full text - MIT Libraries
R Pop, C Conz, KS Lindenberg, S Blesson, B … - Journal of Medical Genetics, 2004 - dx.doi.org
... The junctional CAA homology is set off from the rest of the sequence. ... 29 KCNJ2, the
5' flanking gene to SOX9, is 105 kb from the centromeric deletion breakpoint ...
Cited by 6 - Web Search - jmedgenet.com - jmg.bmjjournals.com - ncbi.nlm.nih.gov - all 6 versions »

Mammalian sex determination: a molecular drama - Full text - MIT Libraries
A Swain, R Lovell-Badge - Development, 1999 - genesdev.org
... In addition, the HMG box domain is relatively well conserved, unlike the rest of
the protein which is so ... A candidate for this type of downstream gene is Sox9. ...
Cited by 134 - Web Search - mcb.berkeley.edu - mne.uni-karlsruhe.de - npb.ucdavis.edu - all 7 versions »

Meeting Report: 16 th International Mouse Genome Conference - Full text - MIT Libraries
SK Loftus - Mammalian Genome, 2003 - springerlink.com
... that a previous Rab3a null allele had an undetected ‘‘rest–activity’’ phenotype ... Qin
(Baylor University) presented data on the role of Sox9 and Fgf9 in ...
Web Search - ncbi.nlm.nih.gov

Molecular aspects of sex differentiation
WY Chan, OM Rennert - Current molec Med, 2002 - ingentaconnect.com
... XX mice carrying a dominant 150 kb deletion, approximately 1 Mb upstream
of Sox9, develop as sterile XX males lacking Sry. ... SOX9 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Investigation of the Viability of Urtica dioica Extracts for Use in Anti-inflammatory Rheumatoid …
S Whyte - stfrancis.edu
... at least one hour; pain occurs at all times and disturbs rest; swelling, fatigue ...
through the down-regulation of transcription factor sox9, which is involved in ...
View as HTML - Web Search

In vitro mesengenic potential of human umbilical cord blood-derived mesenchymal stem cells - Full text - MIT Libraries
EJ Gang, SH Hong, JA Jeong, SH Hwang, SW Kim, IH … - Biochem. Biophys. Res. Commun, 2004 - gencat.net
... Ex- pression of chondrocyte-specific genes, such as Runx2, SOX9, and aggrecan, was ...
of cells were actively involved in pro- liferation while the rest of cells ...
Cited by 2 - View as HTML - Web Search - ncbi.nlm.nih.gov

Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm - Full text - MIT Libraries
M Kishi, K Mizuseki, N Sasai, H Yamazaki, K Shiota … - Development, 2000 - dev.biologists.org
... the time of mid-gastrulation and remains pan-neural during the rest of embryogenesis. ...
For instance, Sox9, which belongs to group E, shares about 60% amino acid ...
Cited by 39 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

der Skelettentwicklung - Full text - MIT Libraries
UK Mainz - Monatsschr Kinderheilkd, 1997 - springerlink.com
... Mutationen des SOX9- Gens (rechts) führen zu einem veränderten Transkriptionsfaktor,
der die ... Nat Genet 10: 330– 336 2. Bruckner P, Rest M van der (1994 ...
Web Search

[CITATION] ARTICLE IN PRESS
NA Theodosiou, CJ Tabin
Web Search

Conserved molecular program regulating cranial and appendicular skeletogenesis - Full text - MIT Libraries
BF Eames, JA Helms - Developmental Dynamics, 2004 - doi.wiley.com
... For ex- ample, Sox9(-/-) Sox5(-/-)Sox6(-/-) Runx2(-/-) and Osx(-/-) mice exhib ... The
rest of the pharyngeal arch cartilaginous skeleton, includ- ing Meckel ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and … - Full text - MIT Libraries
DG Stokes, G Liu, R Dharmavaram, D Hawkins, S … - Biochem J, 2001 - bj.portlandpress.com
... of Sry-type high-mobility-group box (SOX) transcription factors to the enhancer
region was modulated by the culture conditions, as were the mRNA levels for SOX9 ...
Cited by 20 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

DIFERENCIACION SEXUAL EMBRIO-FETAL: DE LAS MOLECULAS A LA ANATOMIA FETAL SEX DIFFERENTIATION: FROM …
PDR Rey - scielo.cl
... DAX1 aumenta su expresión y SOX9 disminuye ... Due to its determining importance in the
rest of sexual development, testicular differentiation due to SRY has been ...
Cached - Web Search - scielo.cl

Muellerian Anomalies - Full text - MIT Libraries
JS Gell - Semin Reprod Med, 2003 - thieme-connect.com
... SOX9 may act to regulate the expression of MIS, resulting in continued high levels
of ... the lower end of the vagina lengthens and ultimately comes to rest on the ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Homeotic transformation of branchial arch identity after Hoxa2 overexpression - Full text - MIT Libraries
GA Grammatopoulos, E Bell, L Toole, A Lumsden, AS … - Development, 2000 - dev.biologists.org
... quail fate-map studies to be r4 derived, while the rest of Meckel ... cartilage
differentiation As Hoxa2 is downregulated in presumptive cartilages, Sox9 and Cbfa1 ...
Cited by 49 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition - Full text - MIT Libraries
BL Thomas, AS Tucker, M Qui, CA Ferguson, Z … - Development, 1997 - dev.biologists.org
... markers of branchial arch neural crest (Barx1) and commitment to chondrogenic
differentiation (Sox9), we show ... 3A. The rest of the embryo was used for genotyping ...
Cited by 67 - Web Search - dev.biologists.org - wwwlib.bionet.nsc.ru - ncbi.nlm.nih.gov - all 5 versions »

The Genetic Basis for Sex Differences in Human Behaviour: Role of the Sex Chromosomes - Full text - MIT Libraries
IW Craig, E Harper, CS Loat - Annals of Human Genetics, 2004 - blackwell-synergy.com
... genes in a complex sex determination cascade, with expression levels of SOX9
(chromosome 17 ... wide re- gions of the chromosome from exchange with the rest of the ...
Cited by 2 - Web Search - ingentaconnect.com - 207.210.67.162 - ncbi.nlm.nih.gov

Modular Arrangement of Cartilage- and Neural Tissue-specific cis-Elements in the Mouse alpha 2 (XI) … - Full text - MIT Libraries
N Tsumaki, T Kimura, K Tanaka, JH Kimura, T Ochi, … - J Biol Chem, 1998 - jbc.org
... Sox9 was shown to bind to the enhancer of the 1(II) collagen gene and ... article via
Infotrieve]; Bernard, M., Yoshioka, H., Rodriguez, E., van der Rest, M., Kimura ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies
J Sharpe, U Ahlgren, P Perry, B Hill, A Ross, J … - Nature, 1976 - ecse.rpi.edu
... situ hybridization on an E11.5 mouse embryo for mRNA expression of the Sox9 gene
(Fig ... expresses E-cadherin at a lower level than is expressed in the rest of the ...
Cited by 42 - View as HTML - Web Search - epcc.ed.ac.uk - dx.doi.org - sciencemag.org - all 6 versions » - Get it from MIT Libraries

Cellular and Molecular Changes During Sex Differentiation of Embryonic Mammalian Gonads
E GONADS - doi.wiley.com
... TESTIS AND OVARY The formation of the basal lamina surround- ing cords defines the
rest of the ... SOX9 gene has recently been found to code for a transcription fac ...
Web Search - doi.wiley.com

Transcriptional Activation by Hyaluronan Oligosaccharide in Chondrocytes
S Ohno, CB Knudson, W Knudson - matrixbiologyinstitute.org
... Deng, JM, Zhang, Z., Behringer, RR, and de Crombrugghe, B. (1999) Sox9 is required ...
GW, and Dempfle, L. (2002) Relative expression software tool (REST) for group ...
Web Search

Sex chromosomes and sex-determining genes: insights from marsupials and monotremes - Full text - MIT Libraries
A Pask, JA Marshall Graves - Cellular and Molecular Life Sciences, 1999 - springerlink.com
... Vertebrate sex determination; comparative analysis; DAX1; SOX9; SOX3; SF1; SRY. ... X.
However, the marsupial and monotreme X lack the genes on the rest of the ...
Cited by 22 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Evolution of the Mammalian Y Chromosome and Sex-Determining Genes
GCOF MAMMALIAN, SEX CHROMOSOMES - doi.wiley.com
... paralogue SOX3, which in turn inhibits an ancient autosomal sex-determining gene
SOX9. ... marsupial and monotreme X, however, lacks the genes on the rest of the ...
Web Search - doi.wiley.com

Intersex disorders: shedding light on male sexual differentiation beyond SRY - Full text - MIT Libraries
HE MacLean, GL Warne, JD Zajac - Clinical Endocrinology, 1997 - ingentaconnect.com
... of DSS ) SOX9 Campomelic ... persistent Müllerian duct syndrome and defects of androgen
metabolism including 5a-reductase deficiency accounting for the rest. ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Early gene response in lithium chloride induced apoptosis
WV Zhang, M Juellig, AR Connolly, NS Stott - APOPTOSIS, 2005 - springerlink.com
... β-catenin in mouse keratinocytes leads to G2 cell cycle ar- rest and apoptosis ... they
do have some features of primary chondrocytes including expression of SOX9. ...
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Clinical Report Microcephaly, Jejunal Atresia, Aberrant Right Bronchus, Ocular Anomalies, and XY Sex … - Full text - MIT Libraries
CE Keegan, E Vilain, M Mohammed, J Lehoczky, WB … - American Journal of Medical Genetics, 2004 - doi.wiley.com
... SOX9 was sequenced according to Kwok et al. [1995]. ... The pregnancy was complicated
by premature labor at 27 weeks and was treated with bed rest. ...
Web Search - ncbi.nlm.nih.gov

Simulated microgravity suppresses osteoblast phenotype, Runx 2 levels and AP-1 transactivation - Full text - MIT Libraries
C Ontiveros, LR McCabe - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... Abstract Conditions of disuse such as bed rest, space flight, and immobilization
result in decreased mechanical loading of ... SOX9 AAG CTG GCA AAG TTG ATC TGA AG ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

The Sexes: New Insights into the X and Y Chromosomes
B Beale - The Scientist, 2001 - the-scientist.com
... Another, called SOX9, combines with SRY to promote the formation of testicular cells ...
an ovary, which starts to produce estrogen and feminizes the rest of the ...
Cached - Web Search - the-scientist.com

Methylation in the Core-promoter Region of the Chondromodulin-I Gene Determines the Cell-specific … - Full text - MIT Libraries
T Aoyama, T Okamoto, S Nagayama, K Nishijo, T … - J Biol Chem, 2004 - jbc.org
... sample was set aside as an input control, and the rest was precleared ... most of OS
irrespective with the histological subtype expressed the SOX9 gene, whereas ...
Cited by 3 - Web Search - jbc.org - intl.jbc.org - ncbi.nlm.nih.gov - all 5 versions »

AMH and AMH receptor defects in persistent Muellerian duct syndrome - Full text - MIT Libraries
N Josso, C Belville, N di Clemente, JY Picard - Human Reproduction Update, 2005 - humupd.oxfordjournals.org
... namely SF-1, SOX9 and GATA-1, the most important one being SOX9 (Arango et al ... domain,
exon 4 codes for most of the transmembrane domain and the rest encodes the ...
Web Search - humupd.oxfordjournals.org - ncbi.nlm.nih.gov

BMP4 promotes chondrocyte proliferation and hypertrophy in the endochondral cranial base
L Shum, X Wang, AA Kane, GH Nuckolls - Int. J. Dev. Biol, 2003 - ijdb.ehu.es
... cas- cade in chondrogenic cells leads to in- creased expression of Sox9, a key ... not
shown), we used the simpler submerged configura- tion for the rest of our ...
Cited by 1 - View as HTML - Web Search - ijdb.ehu.es - ncbi.nlm.nih.gov - Get it from MIT Libraries

AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune … - Full text - MIT Libraries
M Halonen, P Eskelin, AG Myhre, J Perheentupa, ES … - J Clin Endocrinol Metab, 2002 - intl-jcem.endojournals.org
... For the rest of the patients, individual clinicians filled in our ... against 21-, 17-,
tryptophan, phenylalanine and tyrosine hydroxylases, SOX9, aromatic L-amino ...
Cited by 17 - Web Search - intl-jcem.endojournals.org - ncbi.nlm.nih.gov

Cartilage repair with chondrocytes: clinical and cellular aspects
A Lindahl, M Brittberg, L Peterson - Novartis Found Symp, 2003 - doi.wiley.com
... Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B 1999 Sox9 is required ... nasal
cartilage is derived from the cranial neural crest, whereas the rest is from ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

A Kruppel-associated box-zinc finger protein, NT2, represses cell-type-specific promoter activity of … - Full text - MIT Libraries
K Tanaka, N Tsumaki, CA Kozak, Y Matsumoto, F … - Mol. Cell. Biol, 2002 - mcb.asm.org
... T., KS Cheah, SD Chan, VC Lui, MG Mattei, M. van der Rest, K. Ono ... SOX9 is a potent
activator of the chondrocyte-specific enhancer of the proá1(II) collagen gene ...
Cited by 13 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

The degenerate Y chromosome–can conversion save it?
JAM Graves - Reproduction, Fertility and Development - publish.csiro.au
... is represented by chicken chromosome 4.The rest was added more ... For example,
haplo-insufficiency for SOX9 or DMRT1, deletion of ATRX and duplication of DAX1 ...
Web Search - ingentaconnect.com - publish.csiro.au - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Comparative mapping between human chromosome 3 and porcine chromosome 13
M Van Poucke, A Toernsten, M Mattheeuws, A Van … - Cytogenet Cell Genet, 1999 - content.karger.com
... of genes involved in sexual differentiation: AMH, CYP19, DAX1, SF1, SOX2, SOX9,
and WT ... External Resources Van der Rest M, Garrone R: Collagen family of proteins ...
Cited by 14 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries