Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes - Full text - MIT Libraries
JP Ioannidis, SH Ralston, ST Bennett, ML Brandi, D … - JAMA, 2004 - jama.ama-assn.org
Page 1. ORIGINAL CONTRIBUTION Differential Genetic Effects of ESR1 Gene Polymorphisms
on Osteoporosis Outcomes ... 17 2105 Page 2. estrogen receptor (ESR1) gene. ...
Cited by 4 - Web Search - jama.ama-assn.org

About GATA3, HNF3A and XBP1, three genes co-expressed with the oestrogen receptor-a gene (ESR1) in …
M Lacroix, G Leclercq - Molecular and Cellular Endocrinology, 2004 - geocities.com
... Review 3 About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen
receptor- gene (ESR1) in breast cancer 4 5 M. Lacroix ∗ , G. Leclercq 6 ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Oligo GEArray® Human Breast Cancer Biomarkers Microarray
PP Markers - search.cosmobio.co.jp
... IGFBP3, PTEN Transcription factors and regulators: AR, BRCA1, BRCA2, CTNNB1, EGR3,
ESR1, ESR2, FOS, JUN, MYC, NR4A1, PCNA, PGR, RB1, SP1, TNF, TP53, TSG101. ...
View as HTML - Web Search

Tobacco smoking, estrogen receptor {alpha} gene variation and small low density lipoprotein level - Full text - MIT Libraries
AM Shearman, S Demissie, LA Cupples, I Peter, CH … - Human Molecular Genetics, 2005 - hmg.oxfordjournals.org
... LDL receptor expression can be stimulated via an ESR1/Sp1 complex through which
estrogen and related hormone therapies lower plasma LDL concentrations (38 ). ...
Web Search - hmg.oxfordjournals.org

Genetic determinants of osteoporosis.
SH Ralston - Current Opinion in Rheumatology, 2005 - co-rheumatology.com
... on the basis of reduced bone density, implying that the Sp1 allele also ... The oestrogen
receptor α, encoded by the ESR1 gene, is another important functional ...
Web Search - co-rheumatology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The genetics of osteoporosis:'complexities and difficulties' - Full text - MIT Libraries
Y Giguere, F Rousseau - Clinical Genetics, 2000 - blackwell-synergy.com
... Even though the Sp1 COLIA1 gene polymorphism may eventually prove to be of some
value in the prediction of ... The estrogen receptor (ESR1) gene (locus: 6q25.1). ...
Cited by 22 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Suggestive linkage of the parathyroid receptor type 1 to osteoporosis
EL Duncan, MA Brown, J Sinsheimer, J Bell, AJ Carr … - J Bone Miner Res, 1999 - well.ox.ac.uk
... vitamin D receptor (VDR), colony-stimulating factor 1, cal- cium-sensing receptor,
epidermal growth factor (EGF), estrogen receptor 1 (ESR1), fibrillin type 1 ...
Cited by 56 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Differentiation of Caucasians and Chinese at Bone Mass Candidate Genes: Implication for Ethnic … - Full text - MIT Libraries
V Dvornyk, XH Liu, H Shen, SF Lei, LJ Zhao, QR … - Annals of Human Genetics, 2003 - blackwell-synergy.com
... receptor (CASR) gene, the SacI polymorphism of the 2 HS-glycoprotein (AHSG) gene,
the PvuII and XbaI polymorphisms of the estrogen receptor (ESR1) gene, the ...
Cited by 9 - Web Search - ingentaconnect.com - creighton.edu - ncbi.nlm.nih.gov

On the search for the osteoporosis genes: how many more do we need? - Full text - MIT Libraries
C Wuester - Eur J Clin Invest, 2000 - ingentaconnect.com
... patients and a positive association between BMD values and an Sp1 binding site ... seven
other candidate genes such as EGF/COLIA1, COLIIA1/VDR, ESR1, IL-1a, IL-4 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral … - Full text - MIT Libraries
JBJ van Meurs, SC Schuit, AE Weel, M van der Klift … - Human Molecular Genetics, 2003 - hmg.oupjournals.org
... the risk of fractures, the BMD-independent relation of ESR1 genotype with ... observed
for the relation between the collagen-type Ialpha1 Sp1 polymorphism, BMD and ...
Cited by 15 - Web Search - hmg.oupjournals.org - ncbi.nlm.nih.gov

Candidate Genes for Osteoporosis
T Implications - Am J Pharmacogenomics, 2001 - ingentaconnect.com
... body BMD, and gene- gene interaction was found between the PvuII ESR1 and BsmI ... A
single nucleotide polymorphism (SNP) at the Sp1 binding motif in intron 1 of ...
Web Search

The allelic modulation of apolipoprotein E expression by oestrogen: potential relevance for … - Full text - MIT Libraries
JC Lambert, N Coyle, C Lendon - Journal of Medical Genetics, 2004 - jmedgenet.com
... near the -219 G/T polymorphism are several potential SP1 and AP1 ... intracellular
concentrations of oestrogen receptors, the relative proportions of ESR1 to ESR2 ...
Cited by 5 - Cached - Web Search - dx.doi.org - jmg.bmjjournals.com - ncbi.nlm.nih.gov - all 6 versions »

Association of oestrogen receptor {alpha} gene polymorphisms with postmenopausal bone loss, bone … - Full text - MIT Libraries
OME Albagha, U Pettersson, A Stewart, FEA McGuigan … - Journal of Medical Genetics, 2005 - jmg.bmjjournals.com
... a new window], Figure 1 Evolutionarily conserved regions in the human ESR1 gene
compared ... bone density and osteoporosis associated with a polymorphic Sp1 site in ...
Cited by 1 - Web Search - jmedgenet.com - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Molecular Genetics and Epidemiology of Osteoporosis
Y Yamada - Current Pharmacogenomics, 2003 - ingentaconnect.com
... However, ESR1 may be a determinant of bone mass or of genetic predisposition to ... first
base of a consensus binding site for the transcription factor Sp1 in the ...
Web Search

GEArray Q series Human p53 Signaling Pathway Gene Array: AR-SAHS-027
FG Grouping - eurogentec.com
... DAXX, ESR1, FADD, FAF1, GADD45A, GTSE1 (B99), HIF1A, HSPA4 (Hsp70), LRDD, MAP4,
NDRG (RTP), PIG8 (E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP ...
View as HTML - Web Search - eurogentec.be

GEArray Q series Mouse p53 Signaling Pathway Gene Array: AR-SAMM-027
FG Grouping - eurogentec.be
... Esr1, Fadd, Faf1, Gadd45a, Gtse1 (B99), Hif1a, Hspa4 (Hsp70), Lrdd, Mtap4 (Map4),
NDRG-na (RTP), Pmp22, Ppm1d (Wip 1), Rela, Reprimo-Rik, Sfn (14-3-3), Sp1, ...
View as HTML - Web Search - eurogentec.com

GEArray Q series Human p53 Signaling Pathway Gene Array Cat. No.* Kit Size HS-027-2/HS-027N-2 2 …
FG Grouping - tebu-bio.com
... DAXX, ESR1, FADD, FAF1, GADD45A, GTSE1 (B99), HIF1A, HSPA4 (Hsp70), LRDD, MAP4,
NDRG (RTP), PIG8 (E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP ...
View as HTML - Web Search

GEArray Q series Mouse p53 Signaling Pathway Gene Array Cat. No.* Kit Size MM-027-2/MM-027N-2 2 …
FG Grouping - tebu-bio.com
... Esr1, Fadd, Faf1, Gadd45a, Gtse1 (B99), Hif1a, Hspa4 (Hsp70), Lrdd, Mtap4 (Map4),
NDRG-na (RTP), Pmp22, Ppm1d (Wip 1), Rela, Reprimo-Rik, Sfn (14-3-3), Sp1, ...
View as HTML - Web Search

GEArray Q series Human p53 Signaling Pathway Gene Array
FG Grouping - superarray.com
... DAXX, ESR1, FADD, FAF1, GADD45A, GTSE1 (B99), HIF1A, HSPA4 (Hsp70), LRDD, MAP4,
NDRG (RTP), PIG8 (E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP ...
View as HTML - Web Search - superarray.com - cosmobio.co.jp - cosmobio.co.jp - all 5 versions »

GEArray Q series Mouse p53 Signaling Pathway Gene Array
FG Grouping - cosmobio.co.jp
... Esr1, Fadd, Faf1, Gadd45a, Gtse1 (B99), Hif1a, Hspa4 (Hsp70), Lrdd, Mtap4 (Map4),
Ndrg (RTP), Pmp22, Ppm1d (Wip 1), Rela, Reprimo-Rik, Sfn (14-3-3), Sp1, Stat5a ...
View as HTML - Web Search - superarray.com - cosmobio.co.jp - superarray.com

Molecular triangulation: Bridging linkage and molecular-network information for identifying …
M Krauthammer, CA Kaufmann, TC Gilliam, A Rzhetsky - Proceedings of the National Academy of Sciences - pnas.org
... For example, seed genes ESR1 and APP turned out to be the two highest-ranking ... For
example, node SP1, a transcription factor, achieves a triangulation rank of 8 ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - mcb.mcgill.ca - statgen.ncsu.edu - all 8 versions » - Get it from MIT Libraries

Gute Gene fuer kraeftige Knochen?
R Salazar, W Hoeppner - gynundgeburtshilfe.de
... 9. MacDonald HM et al: Col1A1 Sp1 polymor- phism predicts perimenopausal and early
postmenopausal spinal bone loss. ... ESR1 Estrogen-Rezeptor 1 ( ) 6q25.1 ...
View as HTML - Web Search

Molecular mechanisms, physiological consequences and pharmacological implications of estrogen …
T Barkhem, S Nilsson, JA Gustafsson - Am J Pharmacogenomics, 2004 - ingentaconnect.com
... 36] Moreover, raloxifene was more efficient sumably by the formation of an ER :
Sp1 complex ... 72] male patient with a disruptive mutation in ESR1 showed premature ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genetic determinants of bone strength and fracture in humans: dreams and realities - Full text - MIT Libraries
SL Ferrari - Osteoporosis International, 2003 - springerlink.com
... Asians) alters the binding affinity of the transcription factor Sp1, resulting in ...
Receptors Vitamin D VDR Estrogen ESR1 (a) ESR2 (b) Parathyroid hormone PTH1R ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Histone Deacetylase Inhibitor Trichostatin A Represses Estrogen Receptor {alpha}-Dependent … - Full text - MIT Libraries
JP Alao, EW Lam, S Ali, L Buluwela, W Bordogna, P … - Clin Cancer Res, 2004 - clincancerres.aacrjournals.org
... by cyclic AMP response element (CRE) but also by AP-1 and Sp1 sites (27 , 28 ... Primer
pairs used for ER (ESR1) RT-PCR were forward, 5'-CAGATGGCCACAGTTTCC-3', and ...
Cited by 1 - Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

Full Text View - Full text - MIT Libraries
MC Velarde, Y Geng, RR Eason, FA Simmen, RCM … - Biology of Reproduction - bioone.org
... compartments, as well as the numbers of PGR-, HOXA10-, and ESR1-expressing ST ...
transcription element binding protein-1 (BTEB1), a member of the Sp1 family of ...
Web Search - biolreprod.org - biolreprod.org - ncbi.nlm.nih.gov

Gene expression signature of estrogen receptor α status in breast cancer - Full text - MIT Libraries
M Abba, Y Hu, H Sun, J Drake, S Gaddis, K Baggerly … - BMC Genomics, 2005 - biomedcentral.com
... to steroid hormone receptor activity proteins includes: estrogen receptor 1 (ESR1,
ie ERα ... as those involving ER binding to the AP1 or SP1 transcription factors ...
Cached - Web Search - dx.doi.org - pubmedcentral.nih.gov - citebase.eprints.org - all 7 versions »

Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder - Full text - MIT Libraries
DE Comings, R Gade-Andavolu, N Gonzalez, S Wu, D … - Clinical Genetics, 2000 - dx.doi.org
... In contrast to ADHD and ODD, CD preferentially utilized hormone and neuropeptide
genes These included CCK, CYP19 (aromatase cytochrome P-450), ESR1, and INS (p ...
Cited by 32 - Web Search - blackwell-synergy.com - ingentaconnect.com - darkwing.uoregon.edu - all 5 versions »

BMC Genomics - Full text - MIT Libraries
MC Abba, Y Hu, H Sun, JA Drake, S Gaddis, K … - BMC Genomics, 2005 - biomedcentral.com
... DNA-bound transcription factors that in turn bind DNA sequences (eg via AP1, SP1
complexes) [5,6 ... Regulation of transcription related ESR1 (estrogen receptor 1) ...
View as HTML - Web Search - sciencepark.mdanderson.org

Genomewide Linkage Analysis of Stature in Multiple Populations Reveals Several Regions with Evidence … - Full text - MIT Libraries
JN Hirschhorn, CM Lindgren, MJ Daly, A Kirby, SF … - The American Journal of Human Genetics, 2001 - journals.uchicago.edu
... for DRD2 [MIM 126450],VDR [MIM 601769], COL1A1 [MIM 120150], ESR1 [MIM 133430 ... O,
Grant SF, Ralston SH, Delmas PD (1998) Collagen Ialpha1 Sp1 polymorphism, bone ...
Cited by 54 - Web Search - broad.mit.edu - ncbi.nlm.nih.gov

The genetics of panic disorder: state of the art - Full text - MIT Libraries
D van West, S Claes - Acta Neuropsychiatrica, 2004 - blackwell-synergy.com
... They found aC/T transition at position 36 [CCK(-36C/T)] in a GC box, a binding site
for transcription factor Sp1, in the ... Estrogen receptor 1 gene (ESR1). ...
Web Search - ingentaconnect.com

A comprehensive review of genetic association studies
JN Hirschhorn, K Lohmueller, E Byrne, K Hirschhorn - Genet Med, 2002 - psych.umn.edu
... CYP1B1 (55, 56) ERBB2 (57) ESR1 (58) GSTM1 (59) ... UCHL1 (449) Obstetric disease
Endometriosis ESR1 (450) Fetal loss ACP1 (451) CTLA4 (452) EPHX1 (453) F2 (454) ...
Cited by 184 - View as HTML - Web Search - geneticsinmedicine.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

The endothelin receptor B(EDNRB) promoter displays heterogeneous, site specific methylation patterns … - Full text - MIT Libraries
MM Pao, M Tsutsumi, G Liang, E Uzvolgyi, FA … - Human Molecular Genetics, 2001 - hmg.oupjournals.org
... This situation is analogous to the one in the estrogen receptor (ESR1) promoter,
where ... Macleod, D., Charlton, J., Mullins, J. and Bird, AP (1994) Sp1 sites in ...
Cited by 24 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

BOR Papers in Press. Published on June 1, 2005 as DOI: 10.1095/biolreprod. 105.039701
AL Filby, CR Tyler - biolreprod.org
... (5-fold) of fhm esr1 but no ... genes, or indirectly, via interactions with other
transcription factors such as Sp1 or the AP1 complex [4, 5, reviewed in 6-7]. ...
Web Search

Double-strand break repair mediated by DNA end-joining - Full text - MIT Libraries
Y Tsukamoto, H Ikeda - Genes to Cells, 1998 - blackwell-synergy.com
... is a serine/threonine protein kinase that targets p53, c-Myc, Sp1, simian virus
40 T ... has not been identified in yeast, though there are Tel1 and Esr1/Mec1 that ...
Cited by 48 - Web Search - genestocellsonline.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Erb-und Umweltfaktoren in der Entstehung der Osteoporose
U Langenbeck - aerzteblatt.lnsdata.de
... Abstam- mung können der Wirkung des COL- 1A1/SP1-Polymorphismus zugeordnet ... Defektes
im Gen für die Alphakette des Östrogen- rezeptors (ESR1) (83) gezeigt wor ...
Web Search

Vitamin D receptor gene variants and osteoporosis
JM Zmuda, JA Cauley, RE Ferrell - Epidemiol. Rev, 2000 - cdc.gov
... In another report, a complex interaction between the two-locus VDR-ESR1 genotype
and hormone ... 0.7, 1.6) among women with the G/G genotype at an Sp1 binding site ...
Cited by 5 - Cached - Web Search - %5Cwww.cdc.gov - cdc.gov - %5Cwww.cdc.gov

From transcriptional regulation to aggressive behavior
UM D’Souza, A Kel, F Sluyter - Behav. Genet, 2003 - kluweronline.com
... sites for the transcription factor Sp1. ... These include the androgen receptor (AR),
aro- matase, estrogen receptor 1 (ESR1), estrogen receptor 2 (ESR2 ...
Cited by 2 - Web Search - springerlink.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Transcriptional control during mammalian anterior pituitary development - Full text - MIT Libraries
JJ Savage, BC Yaden, P Kiratipranon, SJ Rhodes - Gene, 2003 - www-unix.oit.umass.edu
... ERa ESR1, ESRA Nuclear receptor Important in PRL and gonadotropin gene expression
and lactotrope cell growth ... SP1 Zinc finger Involved in basal gene regulation ...
Cited by 7 - View as HTML - Web Search - ncbi.nlm.nih.gov

Candidate nsSNPs That Can Affect the Functions and Interactions of Cell Cycle Proteins - Full text - MIT Libraries
S Savas, MF Ahmad, M Shariff, DY Kim, H Ozcelik - risk - doi.wiley.com
... RBBP8. Group B: ABI2, BCL3, BCR, CRK, CSNK2A1, CSNK2B, CTNNB1, DNMT1, ESR1,
HDAC1, HSPA8, HSPCA, LMNA, PSMA3, STAT3, TFDP2. Evolutionary ...
Web Search - ijmm.org - ncbi.nlm.nih.gov

Transcriptional profiling of estrogenregulated gene expression via estrogen receptor {alpha} or … - Full text - MIT Libraries
F Stossi, DH Barnett, J Frasor, B Komm, CR Lyttle, … - Endocrinology, 2004 - endo.endojournals.org
... with other transcription factors without direct ERα or ERβ binding to
DNA (ie, at AP-1, Sp1, and other sites) (8-13). In both ...
Cited by 4 - Web Search - endo.endojournals.org

HuGE Review
ERG Polymorphisms, C Cancer - cdc.gov
... The human ER gene (also named ESR1) is located on chromosome 6q25. ... gene (134), with
a VNTR polymorphism at the aromatase gene (135), with the Sp1 binding site ...
Cached - Web Search - cdc.gov

The DNA-dependent protein kinase - Full text - MIT Libraries
GC Smith, SP Jackson - Genes Dev, 1999 - genesdev.org
... kinase was discovered in HeLa cell extracts as an activity that was capable of
phosphorylating SV40 virus large T antigen, transcription factor Sp1, and a ...
Cited by 362 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

GENETIC FACTORS IN BONE DISORDERS
B Oulu - herkules.oulu.fi
Page 1. GENETIC FACTORS IN BONE DISORDERS Osteogenesis imperfecta, juvenile
osteoporosis and stress fractures HEINI HARTIKKA Faculty ...
View as HTML - Web Search

Estrogen Receptor-ß Is Critical to Granulosa Cell Differentiation and the Ovulatory Response to … - Full text - MIT Libraries
JF Couse, MM Yates, BJ Deroo, KS Korach - Endocrinology, 2005 - endo.endojournals.org
... We have previously reported that mice null for estrogen receptor (ER)- (Esr1) or
estrogen receptor-ß (Esr2) also exhibit distinct ovarian defects that lead to ...
Web Search - endo.endojournals.org

Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the … - Full text - MIT Libraries
AS Brodsky, W Li, J Eeckhoute, W Shao, EA Fox, PA … - Cell, 2005 - research.dfci.harvard.edu
Page 1. Cell, Vol. 122, 33–43, July 12, 2005, Copyright ©2005 by Elsevier Inc. DOI
10.1016/j.cell.2005.05.008 Chromosome-Wide Mapping of Estrogen Receptor ...
View as HTML - Web Search

Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, … - Full text - MIT Libraries
C Szpirer, J Szpirer, PV Vooren, F Tissir, JS … - Mammalian Genome, 1998 - springerlink.com
Page 1. Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new
regional localizations, orientation of the linkage groups, and ...
Cited by 32 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cloning of a novel estrogen receptor expressed in rat prostate and ovary - Full text - MIT Libraries
GG Kuiper, E Enmark, M Pelto-Huikko, S Nilsson, JA … - Biochemistry, 1996 - dx.doi.org
... S. Subramanian, M. Tovey, AA Vandenbark, H. Offner, JF Zachary, PD Fillmore, EP
Blankenhorn, JA Gustafsson, and C. Teuscher Estrogen Receptor-1 (Esr1) and -2 ...
Cited by 864 - Web Search - pnas.org - medicine.tamu.edu - pubmedcentral.nih.gov - all 5 versions »

Pathology and molecular genetics of oligodendroglial tumors - Full text - MIT Libraries
C Hartmann, W Mueller, A Deimling - Journal of Molecular Medicine, 2004 - springerlink.com
... This mode of epigenetic deregula- tion has been shown in oligodendrogliomas for
CDKN2A, CDKN2B, p14 ARF , RB1, TP73, DAPK1, ESR1 GSTP1, THBS1, TIMP3, HIC and ...
Web Search - ncbi.nlm.nih.gov

Strategies for Studying Complex Genetic Traits.
BM Nathan, JN Hirschhorn, MR Palmert - theendocrinologist.org
... Most recently, Schuit et al have reported that variation in the estrogen receptor
α gene (ESR1) affects adult stature in women.85 Previous association studies ...
Web Search - theendocrinologist.org