Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid … - Full text - MIT Libraries
RC Gregory, DJ Taxman, D Seshasayee, MH Kensinger, … - Blood, 1996 - bloodjournal.org
... Interaction of GATAl With Erythroid Kruppel-Like Factor and SP1 at Defined ... Using
Drosophils S2 cells, the actions of GATA1, Spl, and erythroid Krllppel-like ...
Cited by 62 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov

Promoter 1 of LMO2, a master gene for hematopoiesis, is regulated by the erythroid specific …
HH Anthropology, M Genetics, G Berlin - Gene Funct. Dis, 2000 - doi.wiley.com
... Transfection of a combination of GATA1 and SP1 or GATA1 and FOG1 [24] expression
vectors leads to no further activation than with the GATA1 expression vector ...
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Table 1. List of Transcription Factors of Which TFBSs Were Found in the Alk1 Regulatory Fragment and …
AP VEGFR, C VEGFR, G ICAM - ahavj.ahajournals.org
... In Enhancer. SP1, VEGFR2, 13 VE-cadherin, 14 ICAM2, 15 eNOS 16, SP3, VE-cadherin
14, ... NF- B, VEGFR2, 17 PECAM, 19 ICAM2 20, GATA, vWF 21, VEGFR2 22. GATA1, ICAM2 ...
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A Placenta-Specific Enhancer of the Human Syncytin Gene - Full text - MIT Libraries
YH Cheng, S Handwerger, S Handwerger - BIOLOGY OF REPRODUCTION, 2005 - biolreprod.org
... placentas having greater reductions in proliferin [12]. Our findings that the
enhancer region binds SP1 and GATA1 and that mutations in ...
Web Search - biolreprod.org - ncbi.nlm.nih.gov

The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity … - Full text - MIT Libraries
Y Ge, TL Jensen, ML Stout, RM Flatley, P Grohar, Y … - Cancer Res, 2004 - intl-cancerres.aacrjournals.org
... The amplicons were digested by XhoI and subcloned into pPacSp1 after excision
of Sp1 to generate GATA1-L and GATA1-S, respectively. ...
Cited by 4 - Web Search - intl-cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular … - Full text - MIT Libraries
D Mukhopadhyay, B Knebelmann, HT Cohen, S Ananth, … - Mol Cell Biol, 1997 - mcb.asm.org
... The von Hippel-Lindau Tumor Suppressor Gene Product Interacts with Sp1 To Repress
Vascular Endothelial ... Sp1 binds the VHL-responsive cis element. ...
Cited by 138 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the … - Full text - MIT Libraries
S Vallian, KV Chin, KS Chang - Mol. Cell. Biol, 1998 - mcb.asm.org
... One set of these factors includes E2F1, GATA1, and YY1, which act synergistically
with Sp1 on DNA to increase transcriptional activity (21, 36, 45, 46). ...
Cited by 57 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Regulation of the human Na-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1 - Full text - MIT Libraries
MG Martin, J Wang, RS Solorzano-Vargas, JT Lam, E … - Am J Physiol Gastrointest Liver Physiol, 2000 - ajpgi.physiology.org
... Numerous transcription factors have been shown to interact with Sp1, including GATA1,
gut-enriched kruppel-like factor, AP1, NF- B, GATA, and HNF-4 (35, 48). ...
Cited by 18 - Web Search - ajpgi.physiology.org - ncbi.nlm.nih.gov

Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... COUP HNF4 1698.5 NFY PBX1 170.4 NFKAPPAB50 SP1 57.6 CEBP GATA1 28.9 AHRARNT
MYCMAX 1424.3 HSF2 NFAT 170.3 BRN2 HNF1 56.6 ISRE MYB 28.7 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis - Full text - MIT Libraries
R Ferreira, K Ohneda, M Yamamoto, S Philipsen - Mol Cell Biol, 2005 - mcb.asm.org
... Interaction between GATA1 and Sp1 or EKLF may play a crucial role in, for example,
bringing regulatory elements such as enhancers and LCRs in close proximity ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Regulation of Myelin Basic Protein Gene Transcription by Sp1 and Pur: Evidence for Association of Sp … - Full text - MIT Libraries
A Tretiakova, A Steplewski, EM Johnson, K Khalili, … - J Cell Physiol, 1999 - doi.wiley.com
... Transcription by Sp1 and Pur : Evidence for Association of Sp1 and Pur in Brain ... The
immunocomplexes were analyzed by Western blot utilizing anti-Sp1 antibody. ...
Cited by 26 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

E2A and HEB Activate the Pre-TCR Promoter During Immature T Cell Development
A Takeuchi, S Yamasaki, K Takase, F Nakatsu, H … - jimmunol.org
... However, because the pT promoter activity was not induced by cotransfection of the
expression vectors of Sp1 or GATA1/2 along with EP180, Sp1 and GATA-1/2 had ...
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Uroporphyrinogen III synthase erythroid promoter mutations in adjacent GATA1 and CP2 elements cause … - Full text - MIT Libraries
C Solis, GI Aizencang, KH Astrin, DF Bishop, RJ … - J Clin Invest, 2001 - jci.org
... of CP2 with transcriptional factors known to form complexes with GATA1, including
FOG ... a cluster of four mutations (–42 to –45) affect a Sp1 binding site (39 ...
Cited by 10 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Transcriptional activation of endoglin and transforming growth factor-beta signaling components by … - Full text - MIT Libraries
LM Botella, T Sanchez-Elsner, F Sanz-Rodriguez, S … - Blood, 2002 - bloodjournal.org
... Transcriptional activation of endoglin and transforming growth factor- signaling
components by cooperative interaction between Sp1 and KLF6: their potential ...
Cited by 17 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Discovery of estrogen receptor α target genes and response elements in breast tumor cells - Full text - MIT Libraries
CY Lin, A Stroem, V Vega, S Li Kong, A Li Yeo, J … - Genome Biology, 2004 - dx.doi.org
... 5, show distinctly that EREs are enriched in the putative direct estrogen-responsive
genes (p = 0.0027) but that binding sites for AP1, Sp1 or GATA1 (which we ...
Cited by 7 - Web Search - bmc.ub.uni-potsdam.de - research.i2r.a-star.edu.sg - genomebiology.com - all 8 versions »

Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 … - Full text - MIT Libraries
V Valverde-Garduno, B Guyot, E Anguita, I Hamlett, … - Blood, 2004 - bloodjournal.org
... could bind in vitro such a complex that could include either GATA1 or GATA2. ... of this
complex function with the ubiquitous transcription factor Sp1 to regulate ...
Cited by 3 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

E2A and HEB activate the pre-TCR alpha promoter during immature T cell development - Full text - MIT Libraries
A Takeuchi, S Yamasaki, K Takase, F Nakatsu, H … - J. Immunol, 2001 - jimmunol.org
... However, because the pT promoter activity was not induced by cotransfection of the
expression vectors of Sp1 or GATA1/2 along with EP180, Sp1 and GATA-1/2 had ...
Cited by 12 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Serotonin transporter: Evolution and impact of polymorphic transcriptional regulation - Full text - MIT Libraries
K Soeeby, SA Larsen, L Olsen, HB Rasmussen, T … - American Journal of Medical Genetics Part B Neuropsychiatric …, 2005 - doi.wiley.com
... Thus, the length of the VNTR is proportional to the number of putative
Sp1/GATA1 elements in the sequence (Table II). Partially ...
Web Search - ncbi.nlm.nih.gov

Multiple Sp1 Binding Sites in the Cardiac/Slow Twitch Muscle Sarcoplamsic Reticulum Ca-ATPase Gene … - Full text - MIT Libraries
DL Baker, V Dave, T Reed, M Periasamy - Mol. Cell. Biol, 2004 - intl.jbc.org
... Known consensus elements for Sp1, Ap2, E-box, CarG, MCAT, and GATA1 are indicated.
B, expression of SERCA2-CAT deletion constructs in Sol8 muscle cells. ...
Cited by 1 - Web Search - intl.jbc.org

A variant in the CD 209 promoter is associated with severity of dengue disease - Full text - MIT Libraries
A Sakuntabhai, C Turbpaiboon, I Casademont, A … - Nature Genetics, 2005 - nature.com
... of CD209, 212 bp 5' of the major transcription start site 7 . This site affects
multiple predicted transcription factor binding sites for Sp1/GATA1/CACCC- and ...
Web Search - nature.com - ncbi.nlm.nih.gov

Transcriptional activation of endoglin and transforming growth factor-signaling components by … - Full text - MIT Libraries
LM Botella, T Sanchez-Elsner, F Sanz-Rodriguez, S … - BLOOD, 2002 - bloodjournal.org
... Transcriptional activation of endoglin and transforming growth factor- signaling
components by cooperative interaction between Sp1 and KLF6: their potential ...
Web Search

Selective impairment of platelet activation to collagen in the absence of GATA1 - Full text - MIT Libraries
SC Hughan, Y Senis, D Best, A Thomas, J Frampton, … - Blood, 2005 - bloodjournal.org
... substitutions at residue D218 of the X-linked transcription factor GATA1 lead to
altered ... glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1. ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Ribosomal protein S19 expression during erythroid differentiation - Full text - MIT Libraries
L Da Costa, G Narla, TN Willig, LL Peters, M Parra … - Blood, 2003 - bloodjournal.org
... These include SP1, GATA1, CACCCBf in the first consensus region, c-Rel and Rel-A
in the third consensus region, and N-Myc transcription factor in the fourth ...
Cited by 10 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Differential Binding of the NFE3 and CP1/NFY Transcription Factors to the Human-and-Globin CCAAT … - Full text - MIT Libraries
AE Ronchi, S Bottardi, C Mazzucchelli, S … - J. Biol. Chem, 2001 - jbc.org
... Some of these mutations have been suggested to create better binding sites for
transcription factors, such as GATA1 and Sp1 (13, 14, 15, 16, 17, 18) ; others ...
Web Search - jbc.org

In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... (2 copies) HNF-3b (2 copies) 700 to 600 GATA1, GATAX, CdxA SRY Mkx-2 GATA2, GATA1
GATA3 600 to 500 GATA1 Sp1 Mkx-2 500 to 400 E47 c-Ets STATx E12 STATx ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Extracellular Signal-Regulated Kinase Induces the Megakaryocyte GPIIb/CD41 Gene through MafB/ … - Full text - MIT Libraries
JR Sevinsky, AM Whalen, NG Ahn - Mol. Cell. Biol, 2004 - pubmedcentral.nih.gov
... when virally delivered into K562 cells (2), was ineffective in enhancing proximal
promoter activation (either alone or in combination with GATA1 and Sp1) (Fig. ...
Cited by 2 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulation of Expression of the Phospholipid Hydroperoxide/Sperm Nucleus Glutathione Peroxidase Gene - Full text - MIT Libraries
TSE PATTERN, IOF FUNCTIONAL, R ELEMENTS - J. Biol. Chem, 2003 - dx.doi.org
... The corresponding trans-regulatory proteins (SP1, ERG1, GATA1, SREBP1, USF1, and
CREBP1) were identified, and in vivo binding of EGR1 and SREBP1 was shown by ...
Cited by 9 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Hemoglobins from bacteria to man: evolution of different patterns of gene expression - Full text - MIT Libraries
R Hardison - J. Exp. Biol, 1998 - jeb.biologists.org
Page 1. Many heme-binding proteins with diverse functions are known, including
electron-transferring cytochromes, intracellular peroxidases ...
Cited by 78 - Web Search - jeb.biologists.org - 163.238.8.180 - ncbi.nlm.nih.gov - all 5 versions »

Genomic structure and promoter analysis of human NeuAc alpha 2, 3Gal beta 1, 3GalNAc alpha 2, 6- … - Full text - MIT Libraries
SW Kim, NY Kang, SH Lee, KW Kim, KS Kim, JH Lee, … - Gene, 2003 - ingentaconnect.com
... region of this gene lacked canonical TATA and CAAT boxes, but contained several
putative binding sites for transcription factors SP1, MZF1, GATA1, LMO2COM, NFAT ...
Cited by 1 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

An Erythrocyte-Specific DNA-Binding Factor Recognizes a Regulatory Sequence Common to All Chicken … - Full text - MIT Libraries
T Evans, M Reitman, G Felsenfeld - Endocrinology, 2005 - pnas.org
... M. Jasinski, P. Keller, Y. Fujiwara, SH Orkin, and M. Bessler GATA1-Cre mediates ...
Factors Including GATA-1, NF-E2, Erythroid Kruppel-like Factor, and Sp1 J. Biol ...
Cited by 97 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 5 versions »

Combinatorial Expression of GATA 4, Nkx 2-5, and Serum Response Factor Directs Early Cardiac Gene … - Full text - MIT Libraries
JL Sepulveda, S Vlahopoulos, D Iyer, N Belaguli, … - J Biol Chem, 2002 - jbc.org
... Sp1 has been reported to physically interact with GATA1 (27-29), Nkx2-1 (30), and
MEF2C (31) and to functionally interact with SRF to regulate the CA promoter ...
Cited by 36 - Web Search - jbc.org - ncbi.nlm.nih.gov

Characterization of the chicken b-globin insulator - Full text - MIT Libraries
JH Chung, AC Bell, G Felsenfeld - Proc. Natl. Acad. Sci. USA, 1997 - pnas.org
... To control for specificity, oligonucleotide competitors with GATA1 and Sp1
binding sites were also used (lanes 9 and 10, respectively). ...
Cited by 19 - Web Search - pubmedcentral.nih.gov - bio.brandeis.edu

Induction of CRMP-2 by GDNF and analysis of the CRMP-2 promoter region. - Full text - MIT Libraries
Y Kodama, Y Murakumo, M Ichihara, K Kawai, Y … - Biochem Biophys Res Commun, 2004 - ncbi.nlm.nih.gov
... 2 expression. The SP1, E2F, and GATA1/2 binding sites appeared to play
some roles in regulation of CRMP-2 expression. As expected ...
Web Search

Intraembryonic Hematopoietic Cell Migration During Vertebrate Development - Full text - MIT Libraries
IIID HW, MW Kieran, FY Chan, LM Barone, K Yee, JA … - Proceedings of the National Academy of Sciences - pnas.org
... which differentiate into endothelial cells in the absence of Gata1 Development,
December 22 ... Cao, C. Zhao, J. Postlethwait, and A. Meng An SP1-like transcription ...
Web Search

Regulation of Expression of the Phospholipid Hydroperoxide/Sperm Nucleus Glutathione Peroxidase Gene - Full text - MIT Libraries
TSE PATTERN, IOF FUNCTIONAL, R ELEMENTS - J. Biol. Chem, 2003 - jbc.org
... The corresponding trans-regulatory proteins (SP1, ERG1, GATA1, SREBP1, USF1, and
CREBP1) were identified, and in vivo binding of EGR1 and SREBP1 was shown by ...
Web Search - jbc.org

Regulatory Sequence Analysis of Coclustering Genes
A TFBS - ahavj.ahajournals.org
... GATA1, 14/52=27, 11/29=38, 4/11=36, 3/6=50, 6/16=38, 2/3=67, 1/4=25, 2/9=22,
0/1=0, 1/1=100. ... SP1, 27/52=52, 8/29=28, 2/11=18, 5/6=83, 14/16=88, 1/3=33, 1/4=25, ...
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Two-phase liquid culture system models normal human adult erythropoiesis at the molecular level - Full text - MIT Libraries
SH Pope, E Fibach, J Sun, K Chin, GP Rodgers - European Journal Of Haematology, 2000 - blackwell-synergy.com
... expression of each gene. During early phase II, c-globin, Sp1, and GATA-2
mRNAs were expressed at their highest levels. As the cells ...
Cited by 16 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Role of USF 1 in the differential expression of the human deoxycytidine kinase gene in acute myeloid …
Y Ge, TL Jensen, DA Tatman, ML Stout, SA Buck, Y … - Leukemia, 2005 - nature.com
... Physical and functional interactions between usf and sp1 proteins regulate human ...
GATA1, cytidine deaminase and the high cure rate of Down syndrome children ...
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Y Ge TL Jensen DA Tatman ML Stout 2
SA Buck, Y Ravindranath, LH Matherly, JW Taub - Leukemia, 2005 - nature.com
... Physical and functional interactions between usf and sp1 proteins regulate human ...
GATA1, cytidine deaminase and the high cure rate of Down syndrome children ...
Web Search

Regulation of the human sodium-phosphate cotransporter NaP i-IIb gene promoter by epidermal growth … - Full text - MIT Libraries
H Xu, JF Collins, L Bai, PR Kiela, FK Ghishan - Am J Physiol Cell Physiol, 2001 - intl-ajpcell.physiology.org
... However, several other putative cis elements were identified, including transcriptional
factors AP1, AP2, AP4, C/EBP, GATA1, and Sp1 binding sites. ...
Cited by 5 - Web Search - intl-ajpcell.physiology.org - ncbi.nlm.nih.gov

Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity … - Full text - MIT Libraries
H Liu, H Kang, R Liu, X Chen, K Zhao - Mol. Cell. Biol, 2002 - mcb.asm.org
... the other (lanes 4 and 8). The preimmune serum and anti-GATA1 antibodies did not
pull down either the Sp1 or BRG1 proteins (lanes 2, 3, 6, and 7). Since the ...
Cited by 14 - Web Search - pubmedcentral.nih.gov - yurim.skku.ac.kr - ucsf.edu - all 8 versions »

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - Mol. Cell. Biol, 1998 - mcb.asm.org
... GATA family proteins. For example, SP1 and EKLF regulate the globin gene
locus control region with GATA1 (38). In the regulation ...
Cited by 39 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei - Full text - MIT Libraries
JH van Doorninck, J van der Wees, A Karis, E … - J. Neurosci, 1999 - jneurosci.org
... Merika M, Orkin SH (1995) Functional synergy and physical interactions of the erythroid
transcription factor GATA1 with the Kruppel family proteins Sp1 and EKLF ...
Cited by 29 - Web Search - jneurosci.org - ncbi.nlm.nih.gov

Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase …
B Langley, JM Gensert, MF Beal, RR Ratan, SK … - Curr Drug Targets CNS Neurol Disord, 2005 - ingentaconnect.com
... deacetylation. Such proteins include, but are not limited to, E2F [14, 15], p53
[16, 17], Sp1 [18], CREB [19] and GATA1 [20, 21]. Acetylation ...
Web Search - ijmm.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

The human ankyrin-1 gene is selectively transcribed in erythroid cell lines despite the presence of … - Full text - MIT Libraries
PG Gallagher, M Romana, WT Tse, SE Lux, BG Forget - Blood, 2000 - bloodjournal.org
... Gregory RC, Taxman DJ, Seshasayee D, et al. Functional interaction of GATA1 with
erythroid Kruppel-like factor and Sp1 at defined erythroid promoters. Blood. ...
Cited by 15 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

The GATA-E box-GATA motif in the EKLF promoter is required for in vivo expression - Full text - MIT Libraries
KP Anderson, SC Crable, JB Lingrel - Blood, 2000 - bloodjournal.org
... a number of other erythroid-specific genes are still expressed in GATA1 null embryos ...
a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc ...
Cited by 8 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Uroporphyrinogen III Synthase - Full text - MIT Libraries
GI Aizencang, DF Bishop, D Forrest, KH Astrin, RJ … - J Biol Chem, 2000 - jbc.org
... transcription factors Sp1, NF1, AP1, Oct1, and NRF2. The TATA-less erythroid-specific
promoter upstream of exon 2A had nine putative GATA1 erythroid enhancer ...
Cited by 16 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genomic organization and mapping of mouse CDV(carnitine deficiency-associated gene expressed in … - Full text - MIT Libraries
M Higashi, K Kobayashi, M Iijima, S Wakana, M … - Mammalian Genome, 2000 - springerlink.com
... TATA box and consensus binding sites for various transcription factors (Nkx-2.5,
Sp1, C/EBP ... the CDV-1 promoter, we found two VNTRs, 13 repeats of GATA1, and 16 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Erythropoietin receptor signalling is required for normal brain development - Full text - MIT Libraries
X Yu, JJ Shacka, JB Eells, C Suarez-Quian, RM … - Development, 2002 - dev.biologists.org
... Fig. 2). GATA1 and SP1 binding sites are primary features of minimal promoter
activity in erythroid cells (Chin et al., 1995). During ...
Cited by 51 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genomic organization, 5'-flanking region and chromosomal localization of the human glutathione … - Full text - MIT Libraries
F Desmots, C Rauch, C Henry, A Guillouzo, F Morel - Biochem. J, 1998 - biochemj.org
... A potential binding site for the transcription factor Sp1 has been identified ... revealed
putative binding sites for transcription factors AP1, GATA1, STAT and NF ...
Cited by 10 - Cached - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov