A Proximal Promoter Domain Containing a Homeodomain-Binding Core Motif Interacts with Multiple … - Full text - MIT Libraries
CH Kim, DY Hwang, JJ Park, KS Kim - The Journal of Neuroscience, 2002 - jneurosci.org
... Antibodies used in this study included antibody against Sp1 (Santa Cruz Biotechnology,
Santa Cruz, CA), antibody against HoxA5 (Babco, Richmond, CA), antibody ...
Cited by 3 - Web Search - jneurosci.org - jneurosci.org - ncbi.nlm.nih.gov - all 5 versions »

Cdx Protein Interaction with Hoxa5 Regulatory Sequences Contributes to Hoxa5 Regional Expression … - Full text - MIT Libraries
S Tabaries, J Lapointe, T Besch, M Carter, J … - Mol Cell Biol, 2005 - mcb.asm.org
... Sequence comparisons of the surrounding Hoxa5 genomic environment revealed that
Cdx consensus ... the addition of a 100-fold excess of an unrelated SP1 primer (Fig ...
Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf 3 … - Full text - MIT Libraries
K Isono, Y Mizutani-Koseki, T Komori, MS Schmidt- … - Genes & Development, 2005 - genesdev.org
... Anti-Sp1 was used as a negative control. ... Significant changes were not observed for
Hoxa5, Hoxb3, Hoxb4, or Hoxd4 expression in the paraxial mesoderm of Sf3b1 ...
Cited by 1 - Web Search - dx.doi.org - genesdev.org - ncbi.nlm.nih.gov

Human Homeobox HOXA 7 Regulates Keratinocyte Transglutaminase Type 1 and Inhibits Differentiation - Full text - MIT Libraries
PT La Celle, RR Polakowska - J Biol Chem, 2001 - jbc.org
... keratinocytes, and new evidence that HOXA7, potentially in conjunction with HOXA5
and HOXAB7 ... binding factors, including members of the AP-1, AP-2, Sp1, and ets ...
Cited by 9 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Clonal T-large granular lymphocyte proliferations associated with clonal B cell lymphoproliferative …
S Durland-Busbice, D Reisman - Leukemia, 2002 - nature.com
... WF, Jaffee E, Marks J, Sukumar S. Control of p53 transcription by HOXA5 may play ...
N, McGee TL, Robbins PD, Dryja T. Oncogenic germ-line mutations in Sp1 and ATF ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

GEArray Q series Mouse p53 Signaling Pathway Gene Array: AR-SAMM-027
FG Grouping - eurogentec.be
... p53 expression: Hoxa5, Nfkb1 ... Hif1a, Hspa4 (Hsp70), Lrdd, Mtap4 (Map4), NDRG-na (RTP),
Pmp22, Ppm1d (Wip 1), Rela, Reprimo-Rik, Sfn (14-3-3), Sp1, Stat5a, Tbp ...
View as HTML - Web Search - eurogentec.com

GEArray Q series Mouse p53 Signaling Pathway Gene Array Cat. No.* Kit Size MM-027-2/MM-027N-2 2 …
FG Grouping - tebu-bio.com
... p53 upstream signal/p53 modifiers: p53 expression: Hoxa5, Nfkb1 ... Map4), NDRG-na (RTP),
Pmp22, Ppm1d (Wip 1), Rela, Reprimo-Rik, Sfn (14-3-3), Sp1, Stat5a, Tbp ...
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GEArray Q series Mouse p53 Signaling Pathway Gene Array
FG Grouping - cosmobio.co.jp
... p53 expression: Hoxa5, Nfkb1 ... B99), Hif1a, Hspa4 (Hsp70), Lrdd, Mtap4 (Map4), Ndrg
(RTP), Pmp22, Ppm1d (Wip 1), Rela, Reprimo-Rik, Sfn (14-3-3), Sp1, Stat5a, Tbp ...
View as HTML - Web Search - superarray.com - cosmobio.co.jp - superarray.com

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone … - Full text - MIT Libraries
Y Zhou, BC Xu, HG Maheshwari, L He, M Reed, M … - Proc Natl Acad Sci USA, 1997 - dx.doi.org
... and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box ...
murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 ...
Cited by 269 - Web Search - intl.pnas.org - pnas.org - pubmedcentral.nih.gov - all 6 versions »

The neuronal microtubule-associated protein 1B is under homeoprotein transcriptional control - Full text - MIT Libraries
ML Montesinos, I Foucher, M Conradt, G Mainguy, L … - J. Neurosci, 2001 - jneurosci.org
... from pTL1mEn2 H1) (Joliot et al., 1998 ), and mouse Hoxa5 (pCL9A5m; derived ... several
regulatory motifs, including two cAMP-responsive elements, an Sp1 site, a ...
Cited by 10 - Web Search - jneurosci.org - ncbi.nlm.nih.gov

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is … - Full text - MIT Libraries
K Sjoegren, JL Liu, K Blad, S Skrtic, O Vidal, V … - Endocr. Rev, 2004 - dx.doi.org
... and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead ... LS
Phillips Insulin-responsive Nuclear Proteins Facilitate Sp1 Interactions with ...
Cited by 152 - Web Search - pnas.org - ncbi.nlm.nih.gov

Identification and classification of p53-regulated genes - Full text - MIT Libraries
J Yu, L Zhang, PM Hwang, C Rago, KW Kinzler, B … - Cancer Res, 2004 - dx.doi.org
... Cell. Biol. Home page H. Chen, S. Chung, and S. Sukumar HOXA5-Induced Apoptosis
in Breast Cancer Cells Is Mediated by Caspases 2 and 8 Mol. Cell. ...
Cited by 199 - Web Search - pnas.org - pubmedcentral.nih.gov - milkpa.idv.tw - all 8 versions »

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is … - Full text - MIT Libraries
K Sjoegren, JL Liu, K Blad, S Skrtic, O Vidal, V … - Endocr. Rev, 2004 - dx.doi.org
... and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead ... LS
Phillips Insulin-responsive Nuclear Proteins Facilitate Sp1 Interactions with ...
Cited by 68 - Web Search - pnas.org - pnas.org - pubmedcentral.nih.gov

TBX 5, a gene mutated in Holt-Oram syndrome, is regulated through a GC box and T-box binding … - Full text - MIT Libraries
G Sun, LE Lewis, X Huang, Q Nguyen, C Price, T … - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... contains a potential homeobox protein HOX-1.3 (HOXA5) binding site ... Sp1-
specificoligonucleotidefromPromega(lane5), but not the nonspecific Sp1 competitor ( ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Hypermethylation of the CpG island of Ras association domain family 1A (RASSF1A), a putative tumor … - Full text - MIT Libraries
R Dammann, G Yang, GP Pfeifer - Cancer Res, 2001 - cancerres.aacrjournals.org
... 18 , 19) , BRCA1 (20, 21, 22, 23) , HIC-1 (24) , 14.3.3 (25) , HOXA5 (26) , and ... We
analyzed 16 CpGs in a 205-bp fragment containing three Sp1 consensus binding ...
Cited by 86 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genes, chromatin, and breast cancer: an epigenetic tale
LM Mielnicki, HL Asch, BB Asch - J Mammary Gland Biol Neoplasia, 2001 - kluweronline.com
... Genes affected by epigenetic changes in breast cancers include HoxA5, p21 WAF ...
HDACI-induced p21 expression was found to be mediated through SP1 sites within ...
Cited by 10 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

A Role for p 53 in Maintaining and Establishing the Quiescence Growth Arrest in Human Cells - Full text - MIT Libraries
K Itahana, GP Dimri, E Hara, Y Itahana, Y Zou, PY … - J Biol Chem, 2002 - jbc.org
... irrelevant, antibody (Fig. 2). SP1 DNA binding served to verify the
concentration and integrity of the extracts (Fig. 2). We also ...
Cited by 18 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulation of Smooth Muscle-specific Gene Expression by Homeodomain Proteins, Hoxa10 and Hoxb8 - Full text - MIT Libraries
O El-Mounayri, JW Triplett, CW Yates, BP Herring - J. Biol. Chem, 2005 - jbc.org
... GATA 4/5/6, Krupple-like zinc finger proteins such as Sp1/3, BTEB3 ... Several other
Hox genes, including HOXA5, HOXA11, HOXB1, HOXB7, and HOXC9 were found to be ...
Web Search - jbc.org - ncbi.nlm.nih.gov

The Role of C/EBP {varepsilon} in the Terminal Stages of Granulocyte Differentiation - Full text - MIT Libraries
JA Lekstrom-Himes - Stem Cells, 2001 - stemcells.alphamedpress.org
... Sp1 is also essential for CD11b expression [20]. ... HoxA9, HoxA10, and HoxA5 are expressed
early during myelopoiesis, with aberrant expression affecting overall ...
Cited by 19 - Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov - all 5 versions »

The STATs of cancer—new molecular targets come of age - Full text - MIT Libraries
H Yu, R Jove - Nat Rev Cancer, 2004 - nature.com
1. Bishop, JM The molecular genetics of cancer. Science 235, 305–311 (1987). |
PubMed | ISI | ChemPort |. 2. Vogelstein, B. & Kinzler ...
Cited by 51 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Plasticity in Skeletal, Cardiac, and Smooth Muscle - Full text - MIT Libraries
AJ Halayko, J Solway - J Appl Physiol, 2001 - jap.org
... in the "stereotypical" smooth muscle contractile protein promoter include Sp1 and
AP2 ... are expressed at high levels, including Mhox, Gax, HoxA5, HoxA11, and ...
Cited by 4 - Cached - Web Search - intl-jap.physiology.org - jap.org - intl-jap.physiology.org

S tem C ells - Full text - MIT Libraries
JA Lekstrom-Himes - Stem Cells, 2001 - immuneweb.xxmc.edu.cn
... Sp1 is also essential for CD11b expression [20]. ... HoxA9, HoxA10, and HoxA5 are expressed
early during myelopoiesis, with aberrant expression affecting overall ...
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Lack of p53 expression in human myeloid leukemias is not due to mutations in transcriptional …
J Zhang, Y Li, B Shen - Leukemia, 2002 - nature.com
... WF, Jaffee E, Marks J, Sukumar S. Control of p53 transcription by HOXA5 may play ...
N, McGee TL, Robbins PD, Dryja T. Oncogenic germ-line mutations in Sp1 and ATF ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

AC Ward, DM Loeb 2, AA Soede-Bobok, IP Touw and AD Friedman 2
G Factors - Leukemia, 2000 - nature.com
... of C/EBP , but not C/EBP , to cooperate with Sp1 in hepatocytes ... 141 HoxA5 is also
expressed during early myelopoiesis – inhi- bition of HoxA5 expression with ...
Web Search

Transcription factors in mouse lung development and function - Full text - MIT Libraries
RH Costa, VV Kalinichenko, L Lim - Am J Physiol Lung Cell Mol Physiol, 2001 - ajplung.physiology.org
... Interestingly, HFH-8 may regulate expression of the lung mesenchymal transcription
factors homeodomain Hoxa5 and Hoxb5 genes, and they share overlapping ...
Cited by 62 - Web Search - ajplung.physiology.org - lungtranscriptome.bwh.harvard.edu - ncbi.nlm.nih.gov

Dcode. org anthology of comparative genomic tools
GG Loots, I Ovcharenko - nar.oxfordjournals.org
... in a new window], Figure 2 Phylogenetic shadowing of the HOXA4/HOXA5/HOXA6/HOXA7 ...
We were specifically searching for HNF1/4 and SP1 TFBS known to enhance the ...
Web Search - pubmedcentral.nih.gov - ivan.dcode.org - citebase.eprints.org - all 5 versions »

Identification of novel functional regions important for the activity of HOXB7 in mammalian cells - Full text - MIT Libraries
Y Yaron, JK McAdara, M Lynch, E Hughes, JC Gasson - J. Immunol, 2001 - jimmunol.org
... pBluescript (pBSK); Stratagene, La Jolla, CA), releasing the HOXA5 coding sequence ...
kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its ...
Cited by 10 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

HOX and Non-HOX Homeobox Genes in Leukemic Hematopoiesis - Full text - MIT Libraries
BM Owens, RG Hawley - Stem Cells, 2002 - stemcells.alphamedpress.org
... HOXA5 overexpression in human bone marrow and cord blood progenitors leads to a
selective greater number of myeloid cells and lower BFU-E numbers and erythroid ...
Cited by 32 - Web Search - stemcells.alphamedpress.org - dx.doi.org - ncbi.nlm.nih.gov

Twelfth International Workshop on the Identification of Transcribed Sequences: Functional, … - Full text - MIT Libraries
T Werner, S Weissman, SB Hedges, K Gardiner - Cytogenet Genome Res, 2002 - content.karger.com
... A number of regulatory factor binding sites (for c-myc, SP1 and p53) were ... 100 kilo-
bases for gorillas and chimpanzees), including the HOXA4, HOXA5, HOXA6, and ...
Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

The Molecular Basis for Abnormal Human Lung Development - Full text - MIT Libraries
F Groenman, S Unger, M Post, M Post, F Alert - Biology of the Neonate, 2005 - content.karger.com
... Mouse studies for Hox show that Hoxa5–/– mice have laryngotracheal malformations
and lung hypoplasia [44] ; Hoxa1–/–; Hoxb1–/– mutants suffer from ...
Web Search - content.karger.com - dx.doi.org - ncbi.nlm.nih.gov

The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... HOXA5 several lines of evidence indicate that HOXA5 gene expression positively
regulates granulocytic ... promoter, an octamer site at bp -54, an Sp1 site at bp -39 ...
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Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... FYN, SYK COL1A2, DNTT,TNC, CDC4, TGFBR2, SP1, SP3, PSG1, ERG, USF1, ETS1 ... TR ALPHA,
HOXB7,TCF3, HOXB8, HOXC8, HOXA5, HOXD10, REN, HOXB3, HOXA3, HOXD3, CREBBP ...
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The molecular basis of lung morphogenesis - Full text - MIT Libraries
D Warburton, M Schwarz, D Tefft, G Flores-Delgado, … - Mech Dev, 2000 - lungtranscriptome.bwh.harvard.edu
... ubiquitous and speci®c transcription factors including GATA-6, HNF-3, Sp1 and Sp3
as ... On the other hand, retinoic acid induces Hoxa5, b5 and b6 gene expression ...
Cited by 151 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

How to make an egg: transcriptional regulation in oocytes - Full text - MIT Libraries
JL Song, GM Wessel - Differentiation, 2005 - blackwell-synergy.com
... The minimal promoter contains a GC box with putative-binding sites for Sp1 and Sp3
transcription factors and a hormone-responsive element (HRE) (Sylvester and ...
Web Search - ncbi.nlm.nih.gov

Gene therapy targeting in the central nervous system
JA Benitez, J Segovia - Curr Gene Ther, 2003 - ingentaconnect.com
Page 1. Current Gene Therapy, 2003, 3, 127-145 127 1566-5232/03 $41.00+.00 ©
2003 Bentham Science Publishers Ltd. Gene Therapy Targeting ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Children and adults with acute lymphoblastic leukaemia have similar gene expression profiles. - Full text - MIT Libraries
E Kuchinskaya, M Heyman, D Grander, M Linderholm, … - European Journal Of Haematology, 2005 - blackwell-synergy.com
Page 1. Children and Adults with Acute Lymphoblastic Leukaemia have similar
Gene Expression Profiles E Kuchinskaya 1,6 , M Heyman ...
Web Search - blackwell-synergy.com - ejh.dk - ncbi.nlm.nih.gov

EVOLUTION OF COMPONENTS OF GENE REGULATION IN DROSOPHILA AND MAMMALS
ET Dermitzakis - etda.libraries.psu.edu
Page 1. The Pennsylvania State University The Graduate School The Eberly College
of Science EVOLUTION OF COMPONENTS OF GENE REGULATION IN DROSOPHILA AND MAMMALS ...
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