Transcriptional autorepression of Msx1 gene is mediated by interactions of Msx1 protein with a multi … - Full text - MIT Libraries
S Shetty, T Takahashi, H Matsui, R Ayengar, R … - Biochem. J, 1999 - biochemj.org
... A graded expression of Sp1 steadily relieved Msx1 autorepression; co-transfection
of cells with 0.75 µg of CMV-Sp1 restored almost completely the activity of ...
Cited by 13 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Interaction of platelet-derived growth factor with thrombospondin 1 - Full text - MIT Libraries
PJ Hogg, KA Hotchkiss, BM Jimenez, P Stathakis, CN … - Biochem J, 1997 - biochemj.org
... Msx1 protein wth a multi-protein complex containing TATA-binding protein, Sp1 and
cAMP-response-element-binding protein-binding protein (CBP/p300) ...
Cited by 18 - View as HTML - Web Search - ncbi.nlm.nih.gov - biochemj.org

A Minimal Murine Msx-1 Gene Promoter. ORGANIZATION OF ITS cis-REGULATORY MOTIFS AND THEIR ROLE IN … - Full text - MIT Libraries
T Takahashi, C Guron, S Shetty, H Matsui, R Raghow - J Biol Chem, 1997 - ncbi.nlm.nih.gov
... Substances: Culture Media, Serum-Free; Homeodomain Proteins; MSX1 transcription
factor; Transcription Factor, Sp1; Transcription Factors; beta-Galactosidase. Grant ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov

Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter - Full text - MIT Libraries
R Mehra-Chaudhary, H Matsui, R Raghow - Biochem. J, 2001 - biochemj.org
... of the presence or absence of the Msx1 recognition motifs on the promoter [18,19].
It was also demonstrated that exogenous co- expression of TBP, Sp1 or cAMP ...
Cited by 12 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Exogenous expression of Msx1 renders myoblasts refractory to differentiation into myotubes and …
S Thompson-Jaeger, R Raghow - Mol Cell Biochem, 2000 - springerlink.com
... of Msx1 gene is mediated by interactions of Msx1 protein with a multi-protein
transcriptional complex containing TATA- binding protein, Sp1 and cAMP-response ...
Cited by 6 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The mechanism of biogenesis and potential function of the two alternatively spliced mRNAs encoded by …
H Matsui, T Takahashi, R Raghow - Molecular and Cellular Biochemistry, 2004 - springerlink.com
... We have demonstrated earlier that the auto-repressive action of Msx1 could
be abolished by exogenous expression of Sp1 [13]. Based ...
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UNCORRECTED
H Matsui, T Takahashi, R Raghow - kluweronline.com
... In transient expression assays, the repressive action of Msx3-s on Msx1 promoter
could also be reversed by co-expression of exogenous Sp1. ...
Web Search

title: SMAD 8 BINDING TO MICE MSX-1 BASAL PROMOTER IS REQUIRED FOR TRANSCRIPTIONAL ACTIVATION
R Binato, CEA Martinez, L Pizzatti, B Robert, E … - biochemj.org
... Copyright 2005 Biochemical Society Page 5. sites for SP1, Y-box, NF1.2, JunB,
CTF/CBP, RXR, Msx1, MTI.1 as described by Gonzalez et al [18]. ...
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Cooperativity between Far Upstream Enhancer and Proximal Promoter Elements of the Human {alpha} 2 (I … - Full text - MIT Libraries
S Tanaka, TT Antoniv, K Liu, L Wang, DJ Wells, F … - J. Biol. Chem, 2004 - jbc.org
... The results are also consistent with implicating the CyRE-bound Sp1 in conferring
bone ... of the dorsolateral dermis derive from the dermatome and express Msx1 (36 ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Influence of promoter potency on the transcriptional effects of YY 1, SRF and Msx-1 in transient … - Full text - MIT Libraries
T Lee, ME Bradley, JL Walowitz - Nucleic Acids Research, 1998 - nar.oupjournals.org
... 5 µg pSV-GAL, pSV-GAL-Msx1, pADH-GAL or pADH-GAL-Msx1 were co ... in mediating
transrepression, which essentially rules out protein factors such as Sp1, YAF2 and ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene - Full text - MIT Libraries
P Ducy, G Karsenty - Mol. Cell. Biol, 1995 - mcb.asm.org
... 17/2.8 nuclear extract and a 200-fold molar excess of an Sp1 oligonucleotide (Table
1 ... in the B region are represented in boldface; a putative MSX1-binding site ...
Cited by 144 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Msx2 and p21 (CIP1/WAF1) mediate the proapoptotic effects of bone morphogenetic protein-4 on … - Full text - MIT Libraries
N Israsena, JA Kessler - J. Neurosci. Res, 2002 - doi.wiley.com
... et al., 2000) Moreover, in the absence of SMAD4, endogenous msx1 and msx2 ... WAF1/ Cip1
promoter in hepatic cells by functional interactions between Sp1 and Smad ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov

Msx-1 and Msx-2 in Mammary Gland Development
K Satoh, E Ginsburg, BK Vonderhaar - Journal of Mammary Gland Biology and Neoplasia, 2004 - kluweronline.com
... Regulation of gene expression through receptor–Sp1 interactions has been ... proliferation
and differentiation during embryogenesis, and in Msx1 and Msx2 null ...
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Genomic approaches to identifying transcriptional regulators of osteoblast differentiation - Full text - MIT Libraries
J Stains, R Civitelli - Genome Biology, 2003 - pubmedcentral.nih.gov
... CBFA1 [1]. Other structurally related zinc-finger family members, SP1 and SP3 ... Homeobox
transcription factors - in particular MSX1, MSX2, DLXs, DLXs, ALX4, SHOX ...
Web Search - genomebiology.com - citebase.eprints.org - dx.doi.org - all 7 versions »

Conserved and muscle group-specific gene expression patterns shape postnatal development of the … - Full text - MIT Libraries
G Cheng, AP Merriam, B Gong, P Leahy, S Khanna, JD … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... prominent, but encountered less frequently (eg, Sp1, 31%; Msx1, 23%; Pou2f1,
23%; Usf, 8%, Myog, 6%, and Myod1, 2%). Consistent with ...
Web Search - dx.doi.org - ncbi.nlm.nih.gov - ijmm.org - all 5 versions »

Constitutive expression of the gene for the cell-specific p 48 DNA-binding subunit of pancreas … - Full text - MIT Libraries
M Knoefler, A Krapp, O Hagenbuechle, PK Wellauer - J Biol Chem, 1996 - jbc.org
... do not necessarily have to be the same as those (Sp1, Cbf) ensuring ... context, it is
interesting to note that a homeobox protein, Msx1, represses transcription ...
Cited by 6 - Web Search - jbc.org - ncbi.nlm.nih.gov

The Homeodomain Protein Barx 2 Promotes Myogenic Differentiation and Is Regulated by Myogenic … - Full text - MIT Libraries
R Meech, H Makarenkova, DB Edelman, FS Jones - J Biol Chem, 2003 - jbc.org
... In addition, several homeobox genes, including Msx1, Pax3, and Pax7 influence ... of
transcription factors, including sequences that match the Sp1 consensus motif ...
Cited by 4 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Regulators of G1 cyclin-dependent kinases and cancers
MH Lee, HY Yang - Cancer Metastasis Rev, 2003 - kluweronline.com
... It is then possible that that Msx1 activates cyclin D1 through interaction with ... Neu
activates cyclin D1 promoter through E2F1 and Sp1 binding sites and this ...
Cited by 7 - Web Search - springerlink.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Nitric oxide donor induces temporal and dose-dependent reduction of gene expression in human … - Full text - MIT Libraries
B Braam, R de Roos, A Dijk, P Boer, JA Post, PP … - Am J Physiol Heart Circ Physiol, 2004 - ajpheart.physiology.org
... at 4 h), with a remarkable downregulation of the transcription factors MSX1, RELB,
and ... response-1 (Egr-1) (36), activating protein-1 (AP-1), Sp1, and nuclear ...
Cited by 1 - Web Search - ajpheart.physiology.org - ncbi.nlm.nih.gov

Comprehensive survey of carapacial ridge-specific genes in turtle implies co-option of some …
S Kuraku, R Usuda, S Kuratani - Evolution and Development, 2005 - blackwell-synergy.com
... whereas T. scripta and E. orbicularis, in which expressions of Fgf10 and Msx1 have
been ... Regulation of the activity of Sp1-related transcription factors. Mol. ...
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Msx homeobox gene family and craniofacial development - Full text - MIT Libraries
S Alappat, ZY Zhang, YP Chen - Cell Res, 2003 - cell-research.com
... The mammalian Msx gene family consists of 3 physically unlinked members, named
Msx1, Msx2, and Msx3[14, 15]. ... Contrary to Msx1, whose expre- ...
Cited by 4 - View as HTML - Web Search - members.tripod.com - ncbi.nlm.nih.gov

P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and …
I Bach, SJ Rhodes, RV Pearse 2nd, T Heinzel, B … - pnas.org
... Promoter of the Neuronal Nitric Oxide Synthase Gene Contains an Sp1-, LIM Homeodomain ...
Sarapura, HL Strouth, DF Gordon, WM Wood, and EC Ridgway Msx1 Is Present ...
Cited by 101 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 5 versions » - Get it from MIT Libraries

Repression of Bone Morphogenetic Protein and Activin-inducible Transcription by Evi-1 - Full text - MIT Libraries
T Alliston, TC Ko, Y Cao, YY Liang, XH Feng, C … - J. Biol. Chem, 2005 - jbc.org
... addition of the Msx1 primers Msx1-U 5'-GCTAAAAATGGCTGCTAA-3' and Msx1-D 5 ... activated
Smad3/4 cooperates with sequence-specific transcription factors (ie Sp1 or c ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Msx homeobox gene family and craniofacial development - Full text - MIT Libraries
YP CHEN - Cell Research, 2003 - cell-research.com
... of Msx1 gene is mediated by interactions of Msx1 protein with a multi-protein
trans-criptional complex containing TATA-binding protein, Sp1 and cAMP-response ...
Cached - Web Search

Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like … - Full text - MIT Libraries
L Kan, M Hu, WA Gomes, JA Kessler - Am J Pathol, 2004 - ajp.amjpathol.org
... Bmp4 transgenic mice overexpressing human BMP4 under control of mouse Msx1 minimal
promoter ... Mouse anti-col I (SP1.D8), mouse anti-col II (CIIC1), mouse anti ...
Cited by 4 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Report A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells …
P Perry, S Sauer, N Billon, WD Richardson, M … - landesbioscience.com
... were mounted in Vectashield (Vector) containing 1 µg/µl DAPI and examined using
a confocal SP1 Leica microscope. ... Ebf (11; B1.1) Msx1 (5; B2) Cripto (9; F2) ...
Web Search - landesbioscience.com

Stimulus-selective Inhibition of Rat Osteocalcin Promoter Induction and Protein-DNA Interactions by … - Full text - MIT Libraries
EP Newberry, JM Boudreaux, DA Towler - J Biol Chem, 1997 - jbc.org
... lanes 3 and 4, respectively), whereas excess unlabeled OCFRE and Sp1 cognates do
not ... By contrast, the homeodomain transcription factors Msx1 and Msx2 regulate ...
Cited by 19 - Web Search - endo.wustl.edu - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Functional Antagonism between Msx 2 and CCAAT/Enhancer-binding Protein alpha in Regulating the Mouse … - Full text - MIT Libraries
YL Zhou, Y Lei, ML Snead - J Biol Chem, 2000 - jbc.org
... In cotransfection assays, Msx1 can repress amelogenin-promoter reporter constructs
only ... receptor, transcription factor v-myb or Sp1, interacts directly with C ...
Cited by 6 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcription of bone and cartilage genes
LJ Sandell, DA Towler - Current Opinion in Orthopaedics, 2002 - co-orthopedics.com
... has been less well characterized; however, others recently identified that Msx1
and Msx2 ... is a 44 kDa C2H2 zinc finger family member related to Sp1 and binds G ...
Cited by 2 - Web Search - co-orthopedics.com

Physiology and pathology of mammary cell proliferation and death
E Scientific - users.unimi.it
Page 1. 1 COST ACTION B20 MAMMARY GLAND DEVELOPMENT, FUNCTION AND CANCER Physiology
and pathology of mammary cell proliferation and death European Scientific ...
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In search of candidate genes critically expressed in the human endometrium during the window of … - Full text - MIT Libraries
S Mirkin, M Arslan, D Churikov, A Corica, JI Diaz, … - Human Reproduction, 2005 - humrep.oxfordjournals.org
... MSX1 is expressed at high levels in adult mice uterine epithelium, and ... transcription
through interaction with other transcription factors (eg Sp1) (Owen et al ...
Web Search - humrep.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov

The Conservation and Regulation of Rat DSP-PP Gene
HH Ritchie, XR Li, CT Hanks, K Knudtson, LH Wang … - Connective Tissue Research, 2002 - taylorandfrancis.metapress.com
... sites previously identified in mouse DSPP promoter were AP1, SP1, AP2, TCF-1 ... example,
extensive sequence conservation between mouse and human Msx1 promoter was ...
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An Otx-related homeodomain protein binds an LHss promoter element important for activation during … - Full text - MIT Libraries
SB Rosenberg, PL Mellon - Mol Endocrinol, 2002 - mend.endojournals.org
... 9A , uppermost bands, SP1+HD). ... to Ptx and Otx HD family members as it fails to interact
with other HD proteins such as Oct-1, Pbx1/2/3, PREP-1, Msx1, and Dlx2 ...
Cited by 15 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

The Polycomb Ezh 2 methyltransferase regulates muscle gene expression and skeletal muscle … - Full text - MIT Libraries
G Caretti, M Di Padova, B Micales, GE Lyons, V … - Genes & Development, 2004 - genesdev.org
... 4K). The levels of the transcription factor Sp1, used as loading control ... Interestingly,
the DNA-binding homeoprotein Msx1, a repressor of muscle differentiation ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

TGF-bold beta signalling from cell membrane to nucleus through SMAD proteins - Full text - MIT Libraries
CH HELDIN, K MIYAZONO, P TEN DIJKE - Nature, 1997 - nature.com
... p15 (ref. 70) and p21 (ref. 71), with involvement of Sp1. Whether SMADs
interact with AP-1 and Sp1 is not known. Studies on the ...
Cited by 664 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity - Full text - MIT Libraries
B Kammandel, K Chowdhury, A Stoykova, S Aparicio, … - Dev. Biol, 1999 - fbmc.fcen.uba.ar
... sequences for various basal promoter elements, such as a conserved TATA-like se-
quence (AATATTT), three CCAAT boxes, and consensus binding sites for Sp1 and Ap ...
Cited by 66 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A PEBP2/AML-1-related factor increases osteocalcin promoter activity through its binding to an … - Full text - MIT Libraries
V Geoffroy, P Ducy, G Karsenty - J Biol Chem, 1995 - jbc.org
... were as described under ``Materials and Methods.'' C, labeled Sp1 oligonucleotide
was ... a binding site for the homeodomain containing proteins MSX1 and MSX2 has ...
Cited by 62 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the … - Full text - MIT Libraries
C Banerjee, SW Hiebert, JL Stein, JB Lian, GS … - Biochemistry, 1996 - dx.doi.org
... Papagerakis, M. Macdougall, B. Robert, and A. Berdal Endogenous Msx1 antisense
transcript ... TL McCarthy, and M. Centrella Multiple and Essential Sp1 Binding Sites ...
Cited by 83 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Transcription factors: Are they a real target for future therapeutic strategies?
M Roth - pharmacologyonline.unisa.it
... described for NF-kappaB and Sp1 and were used in vitro cultured in human ... Fux C, Langer
D, Fussenegger M. Dual-regulated myoD- and msx1-based interventions in ...
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Transcriptional control during mammalian anterior pituitary development - Full text - MIT Libraries
JJ Savage, BC Yaden, P Kiratipranon, SJ Rhodes - Gene, 2003 - www-unix.oit.umass.edu
... development MSX1 HOX7, MSH HD Expressed in thyrotropes; can activate the GSU gene ...
proliferation SP1 Zinc finger Involved in basal gene regulation ...
Cited by 7 - View as HTML - Web Search - ncbi.nlm.nih.gov

Regulation of Msx2 gene expression by steroid hormones in human nonmalignant and malignant breast …
T Malewski, T Milewicz, J Krzysiek, EL … - Cancer Investigation, 2005 - taylorandfrancis.metapress.com
... Increased expression of Msx1 and Msx2 genes in the mammary gland during periods
of active ... Recently, ER interactions with AP1 [28] or SP1 [29,30] were reported ...
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Cell Lineages and Tissue Boundaries in Cardiac Arterial and Venous Poles - Full text - MIT Libraries
S Ausoni, S Sartore - Arteriosclerosis, Thrombosis, and Vascular Biology, 2001 - atvb.ahajournals.org
... Characterization of the rat connexin40 promoter: two Sp1/Sp3 binding sites ... D. A
signaling cascade involving endothelin-1, dHAND and msx1 regulates development ...
Cited by 1 - Web Search - atvb.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 5 versions »

Developmental Diethylstilbestrol Exposure Alters Genetic Pathways of Uterine Cytodifferentiation - Full text - MIT Libraries
WW Huang, Y Yin, Q Bi, TC Chiang, N Garner, J … - Molecular Endocrinology, 2005 - mend.endojournals.org
... Although their role in uterine differentiation is not clear at present, both Msx1
and Msx2 have been shown to function in genetic pathways involving growth ...
Cited by 1 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

Bone morphogenetic protein-2(BMP-2) transactivates Dlx 3 through Smad 1 and Smad 4: alternative mode … - Full text - MIT Libraries
GT Park, MI Morasso - Nucleic Acids Research, 2002 - nar.oupjournals.org
... is dependent on transcription factors such as Dlx3 and Msx1, which have ... mouse
keratinocytes Dlx3 expression is dependent on the activity of Sp1 family members ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

TGF-signalling from cell membrane to nucleus through SMAD proteins - Full text - MIT Libraries
CH Heldin, K Miyazono, P ten Dijke - Nature, 1997 - nature.com
Page 1. Nature © Macmillan Publishers Ltd 1997 NATURE | VOL 390 | 4 DECEMBER 1997
465 review article TGF- signalling from cell membrane to nucleus through ...
Cited by 513 - Web Search - fulcrum.physbio.mssm.edu - uchicago.edu - beagle.colorado.edu - all 5 versions »

TGF-< img border='0' src='/__chars/beta/black/med/base/glyph. gif' align='middle' alt='beta'/> … - Full text - MIT Libraries
CH Heldin, K Miyazono, P ten Dijke - Nature - nature.com
References 1. Massagué, J., Hata, A. & Liu, F. TGF- signalling through the Smad
pathway. Trends Cell Biol. 7, 187 -192 (1997). | Article | ISI | ChemPort |. ...
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Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation … - Full text - MIT Libraries
G Sheng, M dos Reis, CD Stern - Cell, 2003 - 130.15.90.245
... expression of neural (Sox2, Sox3) epidermal (GATA2, GATA3, E-cadherin) or neural
plate border (Msx1) mark- ... neural plate border markers Msx1 and BMP4). ...
Cited by 16 - View as HTML - Web Search - sternlab.anat.ucl.ac.uk - ingentaconnect.com - all 7 versions »

ANALISE DOS POLIMORFISMOS NA REGIAO PROMOTORA DOS GENES TGF β-1, MMP-9, TIMP-2 E PAX-9: CORRELACAO …
O de Piracicaba, H Dental - libdigi.unicamp.br
... entre estes fatores irão elicitar a expressão de diversos fatores de transcrição
como MSX1, MSX2, PAX9, PITX2. ... MSX1 and PAX9 genes in human families. ...
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Animal Model
K Politi, M Szabolcs, P Fisher, A Kljuic, T Ludwig … - American Journal of Pathology, 2004 - ajp.amjpathol.org
... Igf1 Insulin-like growth factor 1 3.2 Hoxb7 Homeobox B7 2.4 Cdc711 Cell division
cycle 71 hom.-like 1 4.0 Msx1 Homeobox, msh-like 1 12.8 Sfrp2 Sec. ...
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A Mouse Model of Uterine Leiomyosarcoma - Full text - MIT Libraries
K Politi, M Szabolcs, P Fisher, A Kljuic, T Ludwig … - American Journal of Pathology, 2004 - ajp.amjpathol.org
... SVST can induce the transcriptional activity of Ap1, Nfkb, Sp1 and other ... For example,
the homeobox-containing Msx1 gene that is expressed exclusively in the ...
Cited by 1 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov