Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the … - Full text - MIT Libraries
PL Pfeffer, M Bouchard, M Busslinger - Development, 2000 - dev.biologists.org
... and 2 (E2) are underlined, and the binding sites of homeodomain (HD), POU, Pax and
Sp1-like zinc finger (Zn) proteins are boxed. Fig. 4. Binding of Pax2/5/8 ...
Cited by 21 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The zebrafish buttonhead-like factor Bts1 is an early regulator of pax2. 1 expression during mid- … - Full text - MIT Libraries
A Tallafuss, TP Wilm, M Crozatier, P Pfeffer, M … - Development, 2001 - dev.biologists.org
... isolation of 11 new zebrafish btd/Sp1-related genes (bts genes). One of these genes,
bts1, is transcribed within the presumptive MHD before her5, pax2.1, wnt1 ...
Cited by 11 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by … - Full text - MIT Libraries
PL Pfeffer, B Payer, G Reim, MP di Magliano, M … - Development, 2002 - dev.biologists.org
... zebrafish transcription factor Bts1, belonging to the Sp1 protein family, was recently
shown to be both necessary and sufficient for inducing the Pax2.1 gene ...
Cited by 12 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Drosophila head segmentation factor Buttonhead interacts with the same TATA box-binding protein- … - Full text - MIT Libraries
F Schoeck, F Sauer, H Jaeckle, BA Purnell - Developmental Biology, 1999 - pnas.org
... Furthermore, because Sp1 is not sufficient to establish all aspects of mandibular ...
buttonhead-like factor Bts1 is an early regulator of pax2.1 expression during ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

PAX genes in development and disease: The role of PAX2 in urogenital tract development
MR Eccles, S He, M Legge, R Kumar, J Fox, C Zhou, … - Int J Dev Biol, 2002 - ijdb.ehu.es
Page 1. PAX genes in development and disease: the role of PAX2 ... In the developing
metaneph- ros, the expression of Pax2 and the related Pax gene, Pax8, Page 3. ...
Cited by 5 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - ijdb.ehu.es - Get it from MIT Libraries

Sp1-like transcription factors are regulators of embryonic development in vertebrates - Full text - MIT Libraries
C Zhao, A Meng - Development Growth & Differentiation, 2005 - blackwell-synergy.com
... of the midbrain/hindbrain boundary through regulating the expression of pax2.1 ... It
is not known whether other members of Sp1-like family compromise the phenotype ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Ataxia-Telangiectasia Mutated Gene Controls Insulin-Like Growth Factor I Receptor Gene Expression in … - Full text - MIT Libraries
L Shahrabani-Gargir, TK Pandita, H Werner - Endocrinology, 2004 - endo.endojournals.org
... human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2. ...
factor-I receptor promoter activity: potential interaction between BRCA1 and Sp1. ...
Cited by 1 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

ATM controls IGF-IR gene expression in a DNA damage response pathway via mechanism/s involving zinc- …
L Shahrabani-Gargir, TK Pandita, H Werner - endo.endojournals.org
... of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2.
Oncogene 14:2689-2700 35. ... and Sp1. Mol. Gen. Metab. 69:130-136 37. ...
Web Search - dx.doi.org - endo.endojournals.org

The Sp1-Related Transcription Factors sp5 and sp5-like Act Downstream of Wnt/-Catenin Signaling in … - Full text - MIT Libraries
G Weidinger, CJ Thorpe, IK Wuennenberg-Stapleton, … - Current Biology, 2005 - microarrays.berkeley.edu
... DOI 10.1016/j.cub.2005.01.041 The Sp1-Related Transcription Factors sp5 and ...
zinc-finger transcription factor of the Sp1 family. sp5- neural genes. ...
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Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... AP1 TCF11 633.5 Oct-1 TST1 130.1 AHRARNT WHN 49.4 AHRARNT SP1 25.7 ATF XBP1
631.2 AP1 PAX2 129.2 GDPCR3HD YY1 49.3 FREAC2 HFH3 25.1 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Cloning and Characterization of the Human PAX 2 Promoter - Full text - MIT Libraries
CK Stayner, HE Cunliffe, TA Ward, MR Eccles - J Biol Chem, 1998 - jbc.org
... By comparison with the murine Pax2 promoter sequences, the NF-IL6 site, an
EGR-1 site, an SP1 site, and three PEA3 sites were all conserved. ...
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Advances in the molecular basis of renal neoplasia
HT Cohen - Curr Opin Nephrol Hypertens, 1999 - co-nephrolhypertens.com
... 80•]. Proposed transcriptional regulators include WT1 itself [81,82],
Sp1 [78•,83], Pax2 [84,85], Pax8 [86,87], and NFκB [88•]. ...
Cited by 9 - Web Search - co-nephrolhypertens.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Activation of the WT1 tumor suppressor gene promoter by Pea3
MT Discenza, D Vaz, JA Hassell, J Pelletier - medicine.mcgill.ca
... WT1 expression is known to be regulated by at least six di¡erent transcription
factors: Sp1, GATA-1, NF- UB, WT1, Pax2, and Pax8. ...
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mBtd is required to maintain signaling during murine limb development - Full text - MIT Libraries
D Treichel, F Schoeck, H Jaeckle, P Gruss, A … - Genes & Development, 2003 - genesdev.org
... Common and diverged functions of the Drosophila gene pair D-Sp1 and buttonhead ... zebrafish
buttonhead-like factor Bts1 is an early regulator of pax2.1 expression ...
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Aberrant expression of Pax-2 mRNA in renal cell carcinoma tissue and parenchyma of the affected … - Full text - MIT Libraries
T Igarashi, T Ueda, H Suzuki, T Tobe, A Komiya, T … - International Journal of Urology, 2001 - blackwell-synergy.com
... The von Hippel-Lindau tumor suppressor gene product interacts with SP1 to repress
vascular ... Dressler GR, Deutsch U, Chowdhury K, Nornes HO, Gruss P. Pax2, a new ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

DEV01733 Supplementary Material
S Figure, S Figure, S Figure - dev.biologists.org
Wnt/ß-catenin regulation of the Sp1-related transcription factor sp5l promotes tail ...
and stained with opl, to mark the prospective telencephalon, pax2, to mark ...
Web Search

A novel subfamily of zinc finger genes involved in embryonic development - Full text - MIT Libraries
M Nakamura, AP Runko, CG Sagerstroem, M Worcester - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... In contrast, a Drosophila protein named D-Sp1 [Wimmer et al., 1996] clusters with
vertebrate Sp8. ... Sp1-mediated transcriptional activation is repressed by Sp3. ...
Web Search - ncbi.nlm.nih.gov

Sp 1 is a critical regulator of the Wilms' tumor-1 gene. - Full text - MIT Libraries
HT Cohen, SA Bossone, G Zhu, GA McDonald, VP … - J Biol Chem, 1997 - jbc.org
... Sp1 may be a prerequisite for WT1 expression, and that Sp1 may have a ... igf 1 receptor
(23), epidermal growth factor receptor (egfr) (24), and Pax2 (25), among ...
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A Far Upstream Cis-element Is Required for Wilms' Tumor-1(WT 1) Gene Expression in Renal Cell … - Full text - MIT Libraries
H Scholz, SA Bossone, HT Cohen, U Akella, WM … - J Biol Chem, 1997 - jbc.org
... growth factor receptor (20), insulin-like growth factor-1 receptor (21), PAX2 (22),
and WT1 ... We have recently shown that Sp1, which binds to a 9-base pair CTC ...
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CELL BIOLOGY-IMMUNOLOGY-PATHOLOGY Suppression of chaperone-mediated autophagy in the renal cortex … - Full text - MIT Libraries
S Sooparb, SR Price, J Shaoguang, HA Franch - Kidney International, 2004 - blackwell-synergy.com
... motif increased 38% and individual KFERQ containing proteins [eg, M2 pyruvate kinase,
glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and pax2] were more ...
Web Search

Chromatin modification of the human imprintedNDN(necdin) gene detected by in vivo footprinting - Full text - MIT Libraries
ML Hanel, JCY Lau, I Paradis, R Drouin, R Wevrick - Journal of Cellular Biochemistry, 2005 - doi.wiley.com
... Predicted SP1 and AP1 binding sites, which occur frequently in GC-rich DNA, as ... consensus
binding sites for the PAX subfamily that includes the PAX2, PAX5, and ...
Web Search - ncbi.nlm.nih.gov

The WT1 Wilms' tumor suppressor gene: a novel target for IGF-I action - Full text - MIT Libraries
I Bentov, D LeRoith, H Werner - Endocrinology, 2003 - endo.endojournals.org
... Transcription factor Sp1 fulfills an important role in controlling WT1 gene expression
(21). ... factors involved in activation of the WT1 gene are NF-κB, PAX2, ...
Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

Distinct enhancers regulate neural expression of Pax7 - Full text - MIT Libraries
D Lang, CB Brown, R Milewski, YQ Jiang, MM Lu, JA … - Genomics, 2003 - uphs.upenn.edu
... P. Urbanek, I. Fetka, MH Meisler, M. Busslinger, Cooperation of Pax2 and Pax5 ... through
the exon 1 enhancer by transcription factors SEF and Sp1, Nucleic Acids ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Expression, Regulation, and Function of Paired-Box Gene 8 in the Human Placenta and Placental Cancer … - Full text - MIT Libraries
E Ferretti, F Arturi, T Mattei, A Scipioni, G Tell … - Endocrinology - endo.endojournals.org
... gene 8; Q-PCR, quantitative PCR; siRNA, small interfering mRNA; SP1, specificity
protein 1 ... AE 1995 Comparative in situ hybridization analysis of PAX2, PAX8, and ...
Web Search - endo.endojournals.org

Endocrinology. First published June 16, 2005 as doi: 10.1210/en. 2005-0084
E FERRETTI, F ARTURI, T MATTEI, A SCIPIONI, G TELL … - endo.endojournals.org
... in DNA-binding to the control oligonucleotide, SP1 (Fig. 3B). ... PAX2, PAX8, and WT1
gene transcription in human fetal kidney and Wilms' tumors. Am J Pathol ...
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Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal … - Full text - MIT Libraries
E Lamar, C Kintner, M Goulding - Development, 2001 - dev.biologists.org
... Double-stranded oligonucleotide Sp1 binding sites dsI and dsII (Jones et al ... Antibodies
used in this study were Pax2, rabbit polyclonal (Dressler and Douglass ...
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An SP 1-like transcription factor Spr 2 acts downstream of Fgf signaling to mediate mesoderm … - Full text - MIT Libraries
J Zhao, Y Cao, C Zhao, J Postlethwait, A Meng - The EMBO Journal, 2003 - nature.com
... 1. Phylogenetic analysis of vertebrate SP1-related factors. ... Dorsal (L) and lateral
(M) views of a bud-stage embryo simultaneously labeled for pax2.1 (red) and ...
Cited by 7 - Web Search - emboj.org - pubmedcentral.nih.gov - embojournal.npgjournals.com - all 6 versions »

WT 1: what has the last decade told us? - Full text - MIT Libraries
M Little, G Holmes, P Walsh - BioEssays, 1999 - doi.wiley.com
... By comparison, the transcription factors Sp1, Pax6, and TFIID predominantly localise
to domains while splicing proteins, as ... (14) Repression of Pax2 by WT1, as ...
Cited by 35 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Suppression of chaperone-mediated autophagy in the renal cortex during acute diabetes mellitus - Full text - MIT Libraries
S Sooparb, SR Price, J Shaoguang, HA Franch - Kidney International, 2004 - ingentaconnect.com
... motif increased 38% and individual KFERQ containing proteins [eg, M2 pyruvate ki-
nase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and pax2] were more ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Evolution of regulatory elements producing a conserved gene expression pattern in Caenorhabditis
X Wang, JF Greenberg, HM Chamberlin - Evolution and Development, 2004 - blackwell-synergy.com
... Combinatorial regulation of the murine RAG-2 promoter by Sp1 and distinct ... Spatially
and temporally restricted expression of Pax2 during murine neurogenesis. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Upregulation of Wilms’ tumor gene 1 (WT1) in desmoid tumors - Full text - MIT Libraries
SA Nik, P Hohenstein, A Jadidizadeh, K Van Dam, A … - Int. J. Cancer, 2005 - doi.wiley.com
... Transcription factor Sp1 fulfills an important role in controlling WT1 gene expression. ...
in activation of the WT1 gene are nuclear factor- B, PAX2, and PAX8. ...
Web Search - ncbi.nlm.nih.gov

TranSignal TM GR-TF Interaction Arrays
PU Manual - panomics.com
... AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A T c Pit 1 Pit 1
Sp1 Sp1 TR TR 1 AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A ...
View as HTML - Web Search - biocat.de

Involvement of Pax-2 in the action of activin A on tubular cell regeneration - Full text - MIT Libraries
A Maeshima, K Maeshima, Y Nojima, I Kojima - J Am Soc Nephrol, 2002 - jasn.org
... of human PAX2 promoter. J Biol Chem 273: 25472–25479, 1998 [Abstract/Free Full Text];
Feng XH, Lin X, Derynck R: Smad2, Smad3 and Smad4 cooperate with Sp1 to ...
Cited by 7 - Web Search - jasn.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a … - Full text - MIT Libraries
Y Fujitani, Y Kajimoto, T Yasuda, TA Matsuoka, H … - Mol Cell Biol, 1999 - mcb.asm.org
... pointed out that this did not totally eliminate the possibility of Pax2/5/8 ... with
DNA-bound transcription factors such as TBP, USF, ATF2/CRE-BP1, Sp1, and c-Jun ...
Cited by 16 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Mutations in SRY and WT1 genes required for gonadal development are not responsible for XY partial … - Full text - MIT Libraries
EB Tagliarini, JG Assumpcao, MR Scolfaro, MP de … - Braz J Med Biol Res, 2005 - scielo.br
... A paternally inherited 3-bp deletion in the SRY 5'UTR Sp1 binding site has ... of the
mature glomerulus function, by repressing or activating PAX2 expression (37,38 ...
Cited by 1 - Cached - Web Search - scielo.br - ncbi.nlm.nih.gov

The gene, protein and glycan structures of laccase from Pleurotus ostreatus
N TABBAM-CNR - Eur. J. Biochem, 1996 - blackwell-synergy.com
... conditions examined. We report in this papcr the cloning and sequencing of the
pax2 gene and of the corresponding cDNA. Mass spectrometry ...
Web Search - ingentaconnect.com - Get it from MIT Libraries

Six family genesÐstructure and function as transcription factors and their roles in development - Full text - MIT Libraries
K Kawakami, S Sato, H Ozaki, K Ikeda - BioEssays - doi.wiley.com
... in zebrafish or in medaka fish induced expression of Emx2 and Pax2, (21,30 ... In the
same study, three Sp1 binding sites and two negative regulatory elements were ...
Cited by 55 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
... AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A T c Pit 1 Pit 1
Sp1 Sp1 TR TR 1 AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A ...
View as HTML - Web Search - biocat.de

Cloning and Characterization of the Human PAX7 Promoter
OV Murmann, F Niggli, BW Schaefer - Biological Chemistry, 2000 - degruyter.com
... factor binding sites (Figure 3). General transcription factors like Sp1, Sp4 (GC ...
Thus, the PAX7 promoter is very similar to the TATA-less PAX2 promoter (Stayner ...
Cited by 2 - Web Search - extenza-eps.com - degruyter.de - ncbi.nlm.nih.gov - all 8 versions » - Get it from MIT Libraries

Structural and functional characterization of the human PAX7 5 0-flanking regulatory region - Full text - MIT Libraries
YV Syagailo, O Okladnova, E Reimer, M Graessle, R … - Gene, 2002 - uni-wuerzburg.de
... described TATA- less human PAX2 and mouse Pax4 gene regulatory regions (Stayner
et al., 1998; Brink et al., 2001). Several potential binding sites for Sp1, AP-2 ...
Cited by 2 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

The role of Wilms’ tumor genes - Full text - MIT Libraries
M Hirose - J Med Invest, 1999 - med.tokushima-u.ac.jp
... for regulating the tissue specific expression of WT1 are not known, although Sp1
and GATA ... of genes such as EGR-1, EGF-R, inhibin-α, Pax2, transforming growth ...
Cited by 17 - View as HTML - Web Search - medical.med.tokushima-u.ac.jp - ncbi.nlm.nih.gov

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity - Full text - MIT Libraries
B Kammandel, K Chowdhury, A Stoykova, S Aparicio, … - Dev. Biol, 1999 - fbmc.fcen.uba.ar
... sequences for various basal promoter elements, such as a conserved TATA-like se-
quence (AATATTT), three CCAAT boxes, and consensus binding sites for Sp1 and Ap ...
Cited by 66 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Mutations in SRY and WT1 genes required for gonadal development are not responsible for XY partial … - Full text - MIT Libraries
JG Assumpcao, MR Scolfaro, MP de Mello, AT Maciel- … - Braz J Med Biol Res, 2005 - scielo.br
... A paternally inherited 3-bp dele- tion in the SRY 5’UTR Sp1 binding site ... of the ma-
ture glomerulus function, by repressing or activating PAX2 expression (37 ...
View as HTML - Web Search - scielo.br

Direct and concentration-dependent regulation of the proneural gene Neurogenin 2 by Pax 6 - Full text - MIT Libraries
R Scardigli, N Baumer, P Gruss, F Guillemot, I Le … - Development, 2003 - dev.biologists.org
... Sections and whole-mount samples were analysed using a confocal microscope (Leica
Sp1). ... 1 is disrupted by incubation with an antibody to Pax6 but not to Pax2. ...
Cited by 7 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov

Methylation profiling of CpG islands in human breast cancer cells - Full text - MIT Libraries
T Huang, MR Perry, DE Laux - Human Molecular Genetics, 1999 - hmg.oupjournals.org
... and -9) contained sequences identical to the 5[prime] end of PAX2 (paired box ... M.,
Nemes, A., Temper, V., Razin, R. and Cedar, H. ( 1995 ) Sp1 elements protect a ...
Cited by 96 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Kruppel-like Factor 15, a Zinc-Finger Transcriptional Regulator, Represses the Rhodopsin and … - Full text - MIT Libraries
DC Otteson, Y Liu, H Lai, CW Wang, S Gray, MK Jain … - Investigative Ophthalmology & Visual Science, 2004 - iovs.org
... Pax2 expression and retinal morphogenesis in the normal and Krd mouse. ... [Abstract/
Free Full Text]; Black AR, Black JD, Azizkhan-Clifford J. Sp1 and Krüppel-like ...
Cited by 2 - Web Search - dx.doi.org - iovs.org - ncbi.nlm.nih.gov

Transcriptional regulation of the human PAX 6 gene promoter. - Full text - MIT Libraries
ZP Xu, GF Saunders - J Biol Chem, 1997 - jbc.org
... length (as in Pax3, Pax4, Pax6, and Pax7) or truncated (as in Pax2, Pax5, and ... region
(at bases 452 to +166), including single binding sites for Sp1 protein (at ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov

Tracing of her 5 progeny in zebrafish transgenics reveals the dynamics of midbrain-hindbrain … - Full text - MIT Libraries
A Tallafuss, L Bally-Cuif - Development, 2003 - dev.biologists.org
... trace the molecular identity of GFP-positive cells in the acerebellar (ace) and
no-isthmus (noi) mutant backgrounds to analyze directly fgf8 and pax2.1 mutant ...
Cited by 2 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Activation of vitamin D receptor by the Wilms’ tumor gene product mediates apoptosis of renal … - Full text - MIT Libraries
KD Wagner, N Wagner, VP Sukhatme, H Scholz - J Am Soc Nephrol, 2001 - jasn.org
... promoting genes, such as insulin-like growth factor 2 (9), Pax2 (10), amphiregulin ...
band shift was obtained with an oligonucleotide containing an Sp1 instead of ...
Cited by 14 - Web Search - jasn.org - ncbi.nlm.nih.gov

BRCA1 is a component of the RNA polymerase II holoenzyme - Full text - MIT Libraries
R Scully, SF Anderson, DM Chao, W Wei, L Ye, RA … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
Full Text of this Article. PDF Version of this Article. Similar articles found
in: PNAS Online ISI Web of Science PubMed. PubMed Citation. ...
Cited by 207 - Web Search - pnas.org - pubmedcentral.nih.gov - parvinlab.bwh.harvard.edu - all 7 versions »