Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... AP2 SP1 1708.7 ER PAX3 173.1 MZF1 RREB1 58.4 MYCMAX WHN 28.9 COUP HNF4
1698.5 NFY PBX1 170.4 NFKAPPAB50 SP1 57.6 CEBP GATA1 28.9 ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Pax3 and the splotch mutations: structure, function, and relationship to teratogenesis, including …
AF Machado, LJ Martin, MD Collins - Curr. Pharm. Design, 2001 - ingentaconnect.com
... Analysis of the 5'-flanking sequence of PAX3 revealed potential binding sites for
a variety of transcription factors including AP-1, AP-2, SP1, TFIID, PEA3, UBP ...
Cited by 7 - Web Search - bentham.org - bentham.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Transcriptional control of Nramp1: a paradigm for the repressive action of c-Myc - Full text - MIT Libraries
AS Lapham, ES Phillips, CH Barton - Biochem. Soc. Trans, 2004 - bst.portlandpress.com
... not affect the ability of c-Myc to activate the Pax3 promoter in ... alternative mechanism
independent of Miz-1, such as interaction with Sp1 (specificity protein 1 ...
View as HTML - Web Search - biochemsoctrans.org - bst.portlandpress.co.uk - ncbi.nlm.nih.gov - all 7 versions »

Activation of Myelin Genes during Transdifferentiation from Melanoma to Glial Cell Phenotype - Full text - MIT Libraries
SG Slutsky, AK Kamaraju, AM Levy, J Chebath, M … - J Biol Chem, 2003 - jbc.org
... Such partners of Sox10, besides Pax3, are, for example, SCIP/Oct-6 (49) and Sp1
(60). SCIP, like Pax3, is an inhibitor that is down-regulated before SC ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov

Cloning and Characterization of the Human PAX7 Promoter
OV Murmann, F Niggli, BW Schaefer - Biological Chemistry, 2000 - degruyter.com
... Furthermore, embryonal rhabdomyosarcoma (eRMS) cells frequently express PAX3
and/or PAX7 ... sites (Figure 3). General transcription factors like Sp1, Sp4 (GC-, GT ...
Cited by 2 - Web Search - extenza-eps.com - degruyter.de - ncbi.nlm.nih.gov - all 8 versions » - Get it from MIT Libraries

ACTIVATION OF MYELIN GENES DURING TRANSDIFFERENTIATION FROM MELANOMA TO GLIAL CELL PHENOTYPE
R Title - jbc.org
... Such partners of Sox10, besides Pax3, are for example SCIP /Oct-6 (49), and Sp1
(60). SCIP, like Pax3, is an inhibitor that is down-regulated ...
Web Search

Cytosine methylation and mammalian development - Full text - MIT Libraries
CP Walsh, TH Bestor - Genes Dev, 1999 - genesdev.org
... Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor ... negative
DNA sequence elements are required to establish the pattern of Pax3 expression ...
Cited by 141 - Web Search - genesdev.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX - Full text - MIT Libraries
JS Michaelson, P Leder - J. Cell Sci, 2003 - jcs.biologists.org
... family of transcription factors, and on overexpression DAXX repressed Pax3-mediated
transcriptional ... E2F1-luc and SP1-luc were kind gifts from P. Farnham ...
Cited by 23 - Web Search - jcs.biologists.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Cloning and Characterization of the Human PAX 2 Promoter - Full text - MIT Libraries
CK Stayner, HE Cunliffe, TA Ward, MR Eccles - J Biol Chem, 1998 - jbc.org
... that were conserved between human and mouse sequences included an SP1 site, recognition ...
site in human fetal kidney, and unlike the PAX5 or murine Pax3 and Pax8 ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Hyperglycemia-induced oxidative stress in diabetic complications - Full text - MIT Libraries
GL King, MR Loeken - Histochemistry and Cell Biology, 2004 - springerlink.com
... As a consequence of insufficient Pax3 expression, differentiation of Pax3-dependent
tis ... activator inhibitor-1 gene promoter and Sp1 transcriptional activation ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

Genetic divergence between mouse and humans: A useful direction for gene pathway analysis
C Ottolenghi, M Vekemans - Teratology, 1998 - doi.wiley.com
... to this autoregulatory DNA site, as this site is apparently occupied by Sp1-like
factors ... C/EBP Timchenko et al., ’95 Gene dosage sen- sitivity PAX3 Steel and ...
Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Homeodomain Protein Barx 2 Promotes Myogenic Differentiation and Is Regulated by Myogenic … - Full text - MIT Libraries
R Meech, H Makarenkova, DB Edelman, FS Jones - J Biol Chem, 2003 - jbc.org
... In addition, several homeobox genes, including Msx1, Pax3, and Pax7 influence ... of
transcription factors, including sequences that match the Sp1 consensus motif ...
Cited by 4 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Selective inhibition of P-glycoprotein expression in multidrug-resistant tumor cells by a designed … - Full text - MIT Libraries
D Xu, D Ye, M Fisher, RL Juliano - J Pharmacol Exp Ther, 2002 - jpet.aspetjournals.org
... Juliano RL (1997) Selection of peptides that functionally replace a zinc finger
in the Sp1 transcription factor ... (2000) An engineered PAX3-KRAB transcriptional ...
Cited by 12 - Web Search - intl-jpet.aspetjournals.org - ncbi.nlm.nih.gov

Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and … - Full text - MIT Libraries
JA Ecsedy, JS Michaelson, P Leder - Mol. Cell. Biol, 2003 - mcb.asm.org
... that Pax3-FKHR circumvents the transcriptional controls normally applied to Pax3
(11). ... The E2F1 and SP1-luciferase reporter vectors (29) were obtained from P ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Distinct enhancers regulate neural expression of Pax7 - Full text - MIT Libraries
D Lang, CB Brown, R Milewski, YQ Jiang, MM Lu, JA … - Genomics, 2003 - uphs.upenn.edu
... gene through the exon 1 enhancer by transcription factors SEF and Sp1, Nucleic Acids ...
[20] AG Borycki, J. Li, F. Jin, CP Emerson, JA Epstein, Pax3 func- tions ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcription factors: Are they a real target for future therapeutic strategies?
M Roth - pharmacologyonline.unisa.it
... epithelial transition and the Pax3/FKHR complex affected the morphogenesis of human ...
described for NF-kappaB and Sp1 and were used in vitro cultured in human ...
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Functional characterization of the 5 Hanking region of human Ubiquitin Fusion Degradation 1 Like …
F Amati, E Conti, A Botta, P Amicucci, B … - Cell Biochem Funct, 2002 - doi.wiley.com
... ve functional consensus sequences respectively for the transcription complex TFIID
and for the transcription factors AP-1 (one site), AP-2 (one) and Sp1 (two). ...
Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas …
JA Bridge, J Liu, SJ Qualman, R Suijkerbuijk, G … - Genes Chromosomes and Cancer, 2002 - doi.wiley.com
... In this investigation, we selected PAX3/FKHR and PAX7/FKHR fusion transcript–positive
and –negative alveolar rhab- domyosarcomas (ARMSs) and embryonal ...
Cited by 12 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Acetylation of histones associated with the p 21 WAF 1/CIP 1 gene by butyrate is not sufficient for … - Full text - MIT Libraries
H Kobayashi, EM Tan, SE Fleming - International Journal of Cancer, 2004 - doi.wiley.com
... NaB stimulated re- cruitment of the transcription factors ZBP89 and Sp1 as well
as GCN5, but did not influence recruitment of Sp3, HDAC1, p300, or CBP. ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Daxx Mediates the Small Ubiquitin-like Modifier-dependent Transcriptional Repression of Smad 4
CC Chang, DY Lin, HI Fang, RH Chen, HM Shih - Journal of Biological Chemistry - jbc.org
... factor-responsive reporter activities, including reporters of CRE, E2F1, Sp1, and
NF ... potential of several transcription factors, such as ETS1 (24), Pax3 (25, 26 ...
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Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators
M Wilson, P Koopman - Curr Opin Genet Dev, 2002 - imb.uq.edu.au
... SOX10 Pax3 N/D c-ret Neural crest [52,53] SOX10 EGR2/Krox-20 N/D Connexin32 Glial
cells [41,53] SOX10 Sp1/3 HMG domain nicotinic acetylcholine PNS [25] ...
Cited by 41 - View as HTML - Web Search - imb.uq.edu.au - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

Report A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells …
P Perry, S Sauer, N Billon, WD Richardson, M … - landesbioscience.com
... DNA replication at a subset of neural-associated genes including Pax3, Pax6, Irx3 ...
containing 1 µg/µl DAPI and examined using a confocal SP1 Leica microscope. ...
Web Search - landesbioscience.com

An In Vitro Approach to Test the Possible Role of Candidate Factors in the Transcriptional …
T BACHETTI, S BORGHINI, R RAVAZZOLO, I CECCHERINI - Gene Expr - ingentaconnect.com
... Gel shift assays performed with oligonucleotides spanning this promoter sequence
showed a change of the SP1 interaction with its binding sites, consequent to ...
Cited by 1 - Web Search

The Gene Encoding the T-box Factor Tbx 2 Is a Target for the Microphthalmia-associated Transcription … - Full text - MIT Libraries
S Carreira, B Liu, CR Goding - J Biol Chem, 2000 - jbc.org
... potential binding sites for several transcription factors, including AP1, AP2, SP1,
SIF-1 ... A precedent for this is provided by both Mitf and Pax3, which are both ...
Cited by 19 - Web Search - mcri.ac.uk - godlab.mcri.ac.uk - ncbi.nlm.nih.gov - all 6 versions »

Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal … - Full text - MIT Libraries
E Lamar, C Kintner, M Goulding - Development, 2001 - dev.biologists.org
... two-hybrid screen searching for proteins that interact with Pax3; however, subsequent ...
Double-stranded oligonucleotide Sp1 binding sites dsI and dsII (Jones et ...
Cited by 11 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the … - Full text - MIT Libraries
PL Pfeffer, M Bouchard, M Busslinger - Development, 2000 - dev.biologists.org
... EMSA analysis The mouse Pax2b, Pax3, Pax5, Pax6, Oct1, Otx2, Gbx2 ...
AGCTCCAAATTTAATTGAAGAGTG-3′; Sp1, 5′-AATTCGATC- GGGGCGGGGCGAGCG-3′; Oct (H2A octamer) ...
Cited by 21 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Impact of manipulations of myogenesis in utero on the performance of adult skeletal muscle - Full text - MIT Libraries
CA Maltin, MI Delday, KD Sinclair, J Steven, AA … - Reproduction, 2001 - reproduction-online.org
... In addition, combined Shh and Wnt-1 signals can induce the expression of the
transcription factor Pax3 in the dorsal lip of the dermomyotome (Stern et al., 1995 ...
Cited by 8 - Web Search - reproduction-online.org - ncbi.nlm.nih.gov

Structural and functional characterization of the human PAX7 5 0-flanking regulatory region - Full text - MIT Libraries
YV Syagailo, O Okladnova, E Reimer, M Graessle, R … - Gene, 2002 - uni-wuerzburg.de
... invitroaswasshownbyfunctionalanalysis.Thus,incontrast to the promoter of the human
PAX3 gene, that ... Several potential binding sites for Sp1, AP-2, AP-4, NF-1 ...
Cited by 2 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

The mechanism of biogenesis and potential function of the two alternatively spliced mRNAs encoded by …
H Matsui, T Takahashi, R Raghow - Molecular and Cellular Biochemistry, 2004 - springerlink.com
... In transient expression assays, the repressive action of Msx3-s on Msx1 promoter
could also be reversed by co-expression of exogenous Sp1. ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Six family genesÐstructure and function as transcription factors and their roles in development - Full text - MIT Libraries
K Kawakami, S Sato, H Ozaki, K Ikeda - BioEssays - doi.wiley.com
... In the same study, three Sp1 binding sites and two negative regulatory elements
were ... expression of Pax3, Six (Six1, Six4) and Eya (Eya1, Eya2) is observed in ...
Cited by 55 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Abundant raw material for cis-regulatory evolution in humans - Full text - MIT Libraries
MV Rockman, GA Wray - Mol. Biol. Evol, 2002 - mbe.oupjournals.org
... factors, especially Sp1, and by the occurrence in our data set of four transcription
factors whose cis-regulation is polymorphic (IRF1, PAX3, PAX6, and VDR). ...
Cited by 65 - Web Search - longitude.weizmann.ac.il - biology.duke.edu - ncbi.nlm.nih.gov - all 8 versions »

Zhao-xia Chen and Arthur D. Riggs 566
GH Yanez, SJ Khan, AM Locovei, IM Pedroso, TM … - pubs.nrc-cnrc.gc.ca
... Specifically, the Pax3 homeodomain can associate with pericentric heterochromatin
while the ... Multiple transcription factors, such as SP1, AP-1, NFκB and the ...
Web Search

A Binding Site for Nuclear Receptors Is Required for the Differential Expression of the Aldolase A … - Full text - MIT Libraries
F Spitz, J Demignon, J Demeurie, JC Sabourin, A … - J Biol Chem, 1998 - jbc.org
... complex A could not be easily distinguished from the additional SP1-like binding ...
that will make head muscles; mice lacking functional Myf-5 and Pax3 genes do ...
Cited by 6 - Web Search - jbc.org - ncbi.nlm.nih.gov

UNCORRECTED
H Matsui, T Takahashi, R Raghow - kluweronline.com
... In transient expression assays, the repressive action of Msx3-s on Msx1 promoter
could also be reversed by co-expression of exogenous Sp1. ...
Web Search

Defects in cardiac conduction system lineages and malignant arrhythmias: developmental pathways and …
TRS Amand, JT Lu, KR Chien - doi.wiley.com
... HF1b is an SP1-related transcription factor preferentially expressed in the conduction
system and ventricular ... Ken, I had a question about your Pax3-Cre work. ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

The chicken telomerase RNA gene: conservation of sequence, regulatory elements and synteny among … - Full text - MIT Libraries
ME Delany, LM Daniels, FTC Alert - Cytogenetic and Genome Research, 2003 - content.karger.com
... on 5) transcription factor binding motifs among the various genomes as well as show
type and number of TERT-related motifs 3) of chicken TR (eg, Sp1, c-Myb, c ...
Cited by 2 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

TranSignal TM GR-TF Interaction Arrays
PU Manual - panomics.com
... AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A T c Pit 1 Pit 1
Sp1 Sp1 TR TR 1 AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A ...
View as HTML - Web Search - biocat.de

Pax 7 distribution in human skeletal muscle biopsies and myogenic tissue cultures - Full text - MIT Libraries
J Reimann, K Brimah, R Schroeder, A Wernig, JR … - Cell and Tissue Research, 2004 - springerlink.com
... precursors do not migrate to the limb bud for lack of Pax3 driven c ... Additional images
were made using a Leica TCS SP1 confocal microscope with the respective ...
Web Search - ncbi.nlm.nih.gov

Differential regulation of polysialyltransferase expression during hippocampus development: … - Full text - MIT Libraries
M Brocco, GD Pollevick, ACC Frasch - Journal of Neuroscience Research, 2003 - doi.wiley.com
... STX and ST8SiaIV/PST genes revealed no extensive homology; however, both promoters
have functional Sp1 site(s ... (2000) have suggested that PAX3—a transcription ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Abstracts of papers presented at the se enth Mammalian Genetics and De elopment Workshop held at the …
SA SHEARDOWN, A NEWALL, DP NORRIS, C JOHNSTON, S … - journals.cambridge.org
... regulatory switch since it overlaps a canonical CAAT box and an SP1 site, and can ...
Among the genes mapped around the Dbf locus, Pax3 might be a candidate gene. ...
Web Search - journals.cambridge.org

Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene … - Full text - MIT Libraries
H Maier, R Ostraat, S Parenti, D Fitzsimmons, LJ … - Nucleic Acids Res, 2003 - nar.oupjournals.org
... The M17 promoter Sp1 binding site is a loading control for protein concentration
and ... Wilson,RB, Rauscher,FJ,III and Barr,FG (1995) Wild type PAX3 protein and ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

MyoD Induces Growth Arrest Independent of Differentiation in Normal and Transformed Cells - Full text - MIT Libraries
M Crescenzi, TP Fleming, AB Lassar, H Weintraub, … - Proceedings of the National Academy of Sciences - pnas.org
... notch inhibits muscle differentiation without affecting Myf5 and Pax3 expression
in ... RW Leggett, SA Armstrong, D. Barry, and CR Mueller Sp1 Is Phosphorylated ...
Cited by 70 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
... AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A T c Pit 1 Pit 1
Sp1 Sp1 TR TR 1 AP-1 (1) AP-1 (1) CREB (1) CREB (1) GA T A GA T A NF A T c NF A ...
View as HTML - Web Search - biocat.de

Akt Modulates STAT 3-mediated Gene Expression through a FKHR(FOXO 1 a)-dependent Mechanism - Full text - MIT Libraries
M Kortylewski, F Feld, KD Krueger, G Bahrenberg, … - Journal of Biological Chemistry, 2003 - jbc.org
... for the Coactivation of IL-6-dependent Gene Expression-- The PAX3-FKHR fusion ... Examples
of such a cooperativity include STAT1 and Sp1 (35), STAT5 and the ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov

Genomic organization, expression, and localization of murine Ran-binding protein 2(RanBP 2) gene - Full text - MIT Libraries
S Fauser, A Aslanukov, R Roepman, PA Ferreira - Mammalian Genome, 2001 - springerlink.com
... E-box/USF, E-box for upstream stimulating factor; AP1/AP2, activator protein 1/2;
SP1, simian-virus-40-protein-1; Nkx-2.5/Csx and Pax3, homeodomain elements ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cell type-specific activation of neuronal nicotinic acetylcholine receptor subunit genes by Sox10 - Full text - MIT Libraries
Q Liu, IN Melnikova, M Hu, PD Gardner - J. Neurosci, 1999 - jneurosci.org
... Moreover, it appears that the transactivation potentials of Sp1 and Sp3 are
differentially ... transcription factors such as Tst-1/Oct6/SCIP or Pax3 (Kuhlbrodt et ...
Cited by 10 - Web Search - jneurosci.org - ncbi.nlm.nih.gov

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage
CR Goding - Signal Transduction, 2000 - genesdev.org
... promoter has been primed already by other regulatory factors such as Pax3 or Sox10 ...
These are an Sp1 transcription factor binding site at 40, an E box element ...
Cited by 79 - Web Search - genesdev.org - godlab.mcri.ac.uk - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

The insulin-sensitive glucose transporter (GLUT4) is involved in early bone growth in control and … - Full text - MIT Libraries
G Maor, E Karnieli - Endocrinology, 1999 - endo.endojournals.org
... GLUT4 and IGF-I receptor genes, contain DNA-binding sites for Sp1 (34, 35 ... Furthermore,
the PAX3 gene product, which is important in early differentiation of the ...
Cited by 12 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease - Full text - MIT Libraries
M Garcia-Barcelo, RW Ganster, VCH Lui, TYY Leon, … - Human Molecular Genetics, 2004 - hmg.oupjournals.org
... For instance, trans-acting regulatory factors such as Sox10 and Pax3 physically
interact with ... as a repressor and may compete with positively acting Sp1 and Sp3 ...
Cited by 2 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Regulation of cholesterol/lipid biosynthetic genes by Egr 2/Krox 20 during peripheral nerve … - Full text - MIT Libraries
SE LeBlanc, R Srinivasan, C Ferri, GM Mager, AL … - Journal of Neurochemistry, 2005 - blackwell-synergy.com
... to as Egr2 and SCIP, respectively), Sox10, nuclear factor- B, Pax3, and Brn2 ... genes
by interacting with a variety of accessory factors, including Sp1 (Sanchez et ...
Web Search - ncbi.nlm.nih.gov