Regulation of Human Monoamine Oxidase B Gene by Sp1 and Sp3 - Full text - MIT Libraries
WK Wong, K Chen, JC Shih - Regulation, 2001 - molpharm.org
... ER), and sex-determining region Y-box 5 (SOX5). Analysis of nine site-directed
mutations of 246/ 99 region reveals that both clusters of Sp1 sites contribute ...
Cited by 12 - Cached - Web Search - molpharm.aspetjournals.org - intl-molpharm.aspetjournals.org - ncbi.nlm.nih.gov - all 5 versions »

Characterization of a new TSPY gene family member in Yq (TSPYq1)
A Ratti, L Stuppia, V Gatta, I Fogh, G Calabrese, … - Cytogenet Cell Genet, 2000 - content.karger.com
... Accession Nos. X74029, X06325, and M98524) with TSPYq1 (AF106331). Conserved
SOX5, SP1, and NFY binding sites are boxed. One TSPYq1 ...
Cited by 6 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Muscle actin genes: A first step towards computational classification of tissue specific promoters - Full text - MIT Libraries
K Frech, K Quandt, T Werner - In Silico Biology, 1998 - iospress.metapress.com
... Poly A ds - CEBP 0.151 0.163 1: 1.081 MyoD - AP1 0.719 0.735 1: 1.022 SP1 - CREB
0.569 0.572 1: 1.006 OCT1 - SOX5 0.718 0.449 1: 0.626 Page 5. K. Frech et al. ...
Cited by 41 - Web Search - bioinfo.de - bioinfo.de - ncbi.nlm.nih.gov - all 5 versions »

SESSION 1: CLINICAL OVERVIEW: SETTING THE SCENE
LS Lohmander, MC Hochberg - Scand J Rheumatol, 2005 - taylorandfrancis.metapress.com
... GST pull-down assays using GST-ESE-1 indicate that Sox9, L-Sox5, Sox6 and Egr-1,
but not Sp1, are potential binding partners of ESE-1. Our results indicate ...
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SESSION 1: CLINICAL OVERVIEW: SETTING THE SCENE
LS Lohmander, MC Hochberg - Scand J Rheumatol, 2005 - dx.doi.org
... GST pull-down assays using GST-ESE-1 indicate that Sox9, L-Sox5, Sox6 and Egr-1,
but not Sp1, are potential binding partners of ESE-1. Our results indicate ...
Web Search - ingentaconnect.com

Molecular regulation of the chondrocyte phenotype - Full text - MIT Libraries
MB Goldring - J Musculoskelet Neuronal Interact, 2002 - ismni.org
... Functional binding motifs for Sp1 family members 27,30,31 , E-box-binding, bHLH ... mobility
group DNA-binding domain and acts cooperatively with L-Sox5 and Sox6 ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov

Divergent Regulation of the Growth-promoting Gene IEX-1 by the p 53 Tumor Suppressor and Sp 1 - Full text - MIT Libraries
HJ Im, MR Pittelkow, R Kumar - J Biol Chem, 2002 - jbc.org
... CCA CCA ATC CTG GCA GAG-3'. Other Sox cDNAs (Sox5, Sox6, and Sox9) were provided
by Dr. Veronique Lefebvre (University of Texas, Houston, TX). pCMV-Sp1 and pCMV ...
Cited by 10 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

SOX9 Exerts a Bifunctional Effect on Type II Collagen Gene (COL2A1) Expression in Chondrocytes …
M KYPRIOTOU, M FOSSARD-DEMOOR, C CHADJICHRISTOS, C … - DNA AND CELL BIOLOGY, 2003 - dx.doi.org
... How- ever, the role of L-SOX5 and SOX6, which have been shown to be equally ... they
may help to understand the role of these fac- tors, together with Sp1 and C ...
Cited by 5 - Web Search - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

The DNA-binding specificity of SOX 9 and other SOX proteins - Full text - MIT Libraries
S Mertin, SG McDowall, VR Harley - Nucleic Acids Research, 1999 - nar.oupjournals.org
... the SCBE, while this Ala is substituted with Ser in SRY and Sox5, which both ... SP1
and YY1 are two examples where their in vitro selected DNA-binding sites ...
Cited by 50 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

The novel zinc finger-containing transcription factor osterix is required for osteoblast … - Full text - MIT Libraries
K Nakashima, X Zhou, G Kunkel, Z Zhang, JM Deng, … - Cell, 2002 - faculty.evansville.edu
... like factor family (Philipsen and Suske, 1999; Turner and Crossley, 1999).
Osx binds to Sp1 and EKLF consensus ... Sox5, Col2a1, and Ihh. ...
Cited by 136 - View as HTML - Web Search - faculty.evansville.edu - ncbi.nlm.nih.gov

Characterization of the Promoter of Human Leukocyte-specific Transcript - Full text - MIT Libraries
X Yu, SM Weissman - J. Biol. Chem, 2000 - intl.jbc.org
... DNA-binding sites within these probe regions, for example, C/EBP and GATA sites
in BI probe, PU.1 and SOX5 sites in BII probe, and an SP1 site in BIV probe. ...
Cited by 3 - Web Search - jbc.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and … - Full text - MIT Libraries
DG Stokes, G Liu, R Dharmavaram, D Hawkins, S … - Biochem J, 2001 - bj.portlandpress.com
... Interestingly, Sp1 is a positive regulator of the COL1A1 gene, but the mechanism ...
factors are SOX tran- scription factors (SOX6, SOX9 and L-SOX5), which have ...
Cited by 20 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Testis Hormone-sensitive Lipase Expression in Spermatids Is Governed by a Short Promoter in … - Full text - MIT Libraries
R Blaise, T Guillaudeux, G Tavernier, D Daegelen, … - J Biol Chem, 2001 - jbc.org
... We showed that the high mobility group domain of Sox5 induces a strong bend in DNA ...
region contains a GT-rich sequence that could bind members of the Sp1 family ...
Cited by 12 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Characterization of the Promoter of Human LST1: A Small Gene with a Complex Pattern of Alternative … - Full text - MIT Libraries
X Yu, SM Weissman, SM Weissman - J. Immunol, 2003 - jbc.org
... EBPβ and GATA sites in BI probe, PU.1 and SOX5 sites in BII probe, and an
SP1 site in BIV probe. 16 Page 17. However, EMSA competition ...
Web Search - jbc.org

Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators
M Wilson, P Koopman - Curr Opin Genet Dev, 2002 - imb.uq.edu.au
... SOX4 Syntenin (PDZ protein) N/D N/A B cells [40 ] SOX5 SOX6 Coiled-coil domains
col2A1 Chondrocytes [49] ... SOX10 Sp1/3 HMG domain nicotinic acetylcholine PNS ...
Cited by 41 - View as HTML - Web Search - imb.uq.edu.au - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

CCAAT-binding factor regulates expression of the beta1 subunit of soluble guanylyl cyclase gene in … - Full text - MIT Libraries
IG Sharina, E Martin, A Thomas, KL Uray, F Murad - Proc Natl Acad Sci USA, 2003 - intl.pnas.org
... 4B, lane 4), but not in the presence of GFI1 or SP1 antibodies (data not ... 20, 21),
and factors involved in morphogenesis and development, such as Sox5, Prx2 and ...
Cited by 4 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Testis Hormone-sensitive Lipase Expression in Spermatids Is Governed by a Short Promoter in …
B Evrard, A Mairal, C Holm, B Jegou, D Langin - jbc.org
Page 1. Testis Hormone-sensitive Lipase Expression in Spermatids Is Governed
by a Short Promoter in Transgenic Mice* Received for ...
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The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon- … - Full text - MIT Libraries
M Osaki, L Tan, BK Choy, Y Yoshida, KS Cheah, PE … - Biochem. J, 2003 - biochemj.org
... intronic enhancer, which binds Sox9, L-Sox5, and Sox6 [3], is required for cartilage ...
for binding Sp1, basic HLH/E box binding proteins, and cKrox, and expresses ...
Cited by 15 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Isolation and characterization of the human syncytin gene promoter - Full text - MIT Libraries
YH Cheng, BD Richardson, MA Hubert, S Handwerger - Biol Reprod, 2004 - bioone.org
... FP3 contains a Sox5 binding site and a putative TATA box ... the HERV-W gene revealed
a putative CCAAT box and many putative cis-acting elements, including Sp1, AP-1 ...
Cited by 5 - Web Search - biolreprod.org - biolreprod.org - ncbi.nlm.nih.gov - all 7 versions »

Mouseµ opioid receptor distal promoter transcriptional regulation by SOX proteins - Full text - MIT Libraries
CK Hwang, X Wu, G Wang, CS Kim, HH Loh - J. Biol. Chem, 2003 - jbc.org
... 5, SOX5-BS12 (26); lane 6, TCF1 (T cell receptor chain enhancer) (27); lane 7, SRY
(sex region of the Y chromosome) (28). The nonspecific competitor Sp1 was ...
Cited by 6 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Sp 1 and Sp 3 Transcription Factors Mediate Interleukin-1 {beta} Down-regulation of Human Type II … - Full text - MIT Libraries
C Chadjichristos, C Ghayor, M Kypriotou, G Martin, … - J Biol Chem, 2003 - jbc.org
... form chondrocyte-specific complexes, such as SOX9, L-SOX5, and SOX6 (6, 7), and
also with factors having less tissue-specific expression, such as Sp1, Sp3, and ...
Cited by 3 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta - Full text - MIT Libraries
L Tan, H Peng, M Osaki, BK Choy, PE Auron, LJ … - J. Biol. Chem, 2003 - jbc.org
... 35, 39), and recent work has shown that Sp3 represses Sp1-mediated transactivation ...
group (HMG) DNA binding domain and acts cooperatively with L-Sox5 and Sox6 ...
Cited by 16 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Highly conserved proximal promoter element harboring paired Sox9-binding sites contributes to the … - Full text - MIT Libraries
O Rentsendorj, A Nagy, I Sinko, A Daraba, E Barta, … - Biochem J, 2005 - biochemj.org
... 5) and also at G residues of several Sp1-like elements located between SII and the
TATA motif ... Sox9, L-Sox5 and Sox6 interact with the Pe1 element in vitro ...
View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov

Transcription of bone and cartilage genes
LJ Sandell, DA Towler - Current Opinion in Orthopaedics, 2002 - co-orthopedics.com
... Osx is a 44 kDa C2H2 zinc finger family member related to Sp1 and binds G/C rich
DNA ... 9. Lefebvre V, Li P, de Crombrugghe B: A new long form of Sox5 (L-Sox5 ...
Cited by 2 - Web Search - co-orthopedics.com

Floppy SOX: mutual induced fit in HMG (high-mobility group) box-DNA recognition - Full text - MIT Libraries
MA Weiss - Mol. Endocrinol, 2001 - mend.endojournals.org
... synergy between Sox10 and the classical Zn finger protein Sp1 in transcriptional ...
transcriptional activator Sox-4 and testis-specific factor Sox5 in the absence ...
Cited by 14 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic … - Full text - MIT Libraries
H Kasimiotis, MA Myers, A Argentaro, S Mertin, S … - Diabetes, 2000 - diabetes.diabetesjournals.org
... 1 3 was determined by 5 RACE using three antisense primers (SP1 5 GCAGCCAGTTCTTCTGCT ...
mammals, the SOX13 HMG domain sequence shows 90% identity to SOX5 and Sox6 ...
Cited by 19 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Modelling and identification of transcription-factor binding motifs in human chondrogenesis - Full text - MIT Libraries
Y Liu, H Yokota - Syst. Biol, 2004 - ieeexplore.ieee.org
... of 5 0 -AGGGCGGGTGGGCGGG-3 0 consisting of Sp1 binding motif was used. ... Sp1 was known
to be stimulatory in chondrogenesis, and was used as a positive control. ...
Web Search - iee.org - ieeexplore.ieee.org

Genetic divergence between mouse and humans: A useful direction for gene pathway analysis
C Ottolenghi, M Vekemans - Teratology, 1998 - doi.wiley.com
... SOX5 expression in man is more widely distributed than in mice, and additionally
humans ... DNA site, as this site is apparently occupied by Sp1-like factors. ...
Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation of Human COL2A1 Gene Expression in Chondrocytes - Full text - MIT Libraries
IOFCKR ELEMENTS, MBYP ALTERATION - J. Biol. Chem, 2000 - jbc.org
... Other transcription factors, including L-SOX5, SOX6, and proteins not yet characterized,
are ... Moreover, an Sp1 binding activity has been shown to be involved in ...
Web Search - jbc.org

Induction of the Human Papillomavirus Type 31 Late Promoter Requires Differentiation but Not DNA … - Full text - MIT Libraries
KM Spink, LA Laimins - J Virol, 2005 - jvi.asm.org
... inhibition of transcription appears to act by displacement of Sp1, along with ... Additional
potential transcription factor binding sites for Oct-1, SOX5, and SRY ...
Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Expression of the human oestrogen receptor-alpha gene is regulated by promoter F in MG-63 … - Full text - MIT Libraries
E Lambertini, L Penolazzi, S Giordano, L Del Senno … - Biochem. J, 2003 - biochemj.org
... corebinding factor], GATA-1 [(A/T)GATA(A/G) binding protein], Sox5 [sex- determining ...
by the equivalence of binding of the extracts to the Sp1 and nuclear ...
Cited by 2 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The murine homolog of the HIN 200 family, Ifi 204, is constitutively expressed in myeloid cells and …
M Gariglio, M De Andrea, M Lembo, M RAVOTTO, C … - J. Leukocyte Biol, 1998 - jleukbio.org
... provided evidence that binding of both the PU.1 and the Sp1 transcrip- tion ... binding
sites are present, together with AML1 (one match) and Sox5 (two matches ...
Cited by 18 - Web Search - jleukbio.org - jleukbio.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

EXPRESSION OF HUMAN ESTROGEN RECEPTOR α {alpha} GENE IS REGULATED BY PROMOTER F IN MG-63 …
E LAMBERTINI, L PENOLAZZI, S GIORDANO, L DEL SENNO … - biochemj.org
... regulatory elements for many transcription factors including Cbfa1, GATA-1, SOX5,
SRY, AP1 and CP2. ... extracts to the Sp1 and NF-kB sequences (see Fig. 4). ...
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Serum-Free Growth Medium Sustains Commitment of Human Articular Chondrocyte through Maintenance of … - Full text - MIT Libraries
B DOZIN - TISSUE ENGINEERING, 2004 - dx.doi.org
... by peroxidase-based immunochemistry 12 with the monoclonal antibodies SP1.D8 (anti ...
and the presence of ad- ditional cooperative effectors, such as Sox5, Sox6 or ...
Cited by 2 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions »

Regulation of chondrocyte gene expression
TM Hering - Front Biosci, 1999 - bioscience.org
Page 1. [Frontiers in Bioscience 4, d743-761, October 15, 1999] 743 REGULATION
OF CHONDROCYTE GENE EXPRESSION Thomas M Hering Department ...
Cited by 18 - View as HTML - Web Search - bioscience.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Structure and Expression of the Scallop &OHgr;-Crystallin Gene - Full text - MIT Libraries
E Carosa, Z Kozmik, JE Rall, J Piatigorsky - J. Biol. Chem, 2002 - jbc.org
... revealed a group of ubiquitous transcription factors (AP-1, USF, CREB, and Sp1)
as well ... 1, three USF, two NKx25, and one CREB/Jun, Oct1, and Sox5 DNA-binding ...
Cited by 7 - Web Search - jbc.org - ncbi.nlm.nih.gov

Charge movement and transcription regulation of L-type calcium channel alpha 1 S in skeletal muscle … - Full text - MIT Libraries
Z Zheng, ZM Wang, O Delbono - The Journal of Physiology, 2002 - jphysiol.org
... sequence (CCCAGCCC), found at position -148 to -139 represents a binding site for
SP1. ... A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in ...
Cited by 7 - Web Search - blackwell-synergy.com - dx.doi.org - jp.physoc.org - all 7 versions »

Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene … - Full text - MIT Libraries
A Klooster, S Bernier - Arthritis Res Ther, 2004 - dx.doi.org
... activity. There are, however, alternate sites within these genes that may govern
expression, such as SP1/SP3, C-Krox, and Stat1 [45-48]. ...
Web Search - pubmedcentral.nih.gov - bmc.ub.uni-potsdam.de - arthritis-research.com - all 8 versions »

ACCESS PUBMED REPRINTS CAVEAT LECTOR
TM Hering - Frontiers in Bioscience, 1999 - bioscience.org
... aggrecan and COL2A1 promoters were found to contain numerous clusters of SP1 sites. ...
specific enhancer-binding proteins, include a new long form of Sox5 (L-Sox5 ...
Cited by 2 - Cached - Web Search - xylian.igh.cnrs.fr - bioscience.org - xylian.igh.cnrs.fr - all 6 versions »

Sequence analysis of porcine endogenous retrovirus long terminal repeats and identification of … - Full text - MIT Libraries
CA Wilson, S Laeeq, A Ritzhaupt, W Colon-Moran, FK … - J Virol, 2003 - jvi.asm.org
... These binding sites include those for the transcription factors SOX5, Ets-1, Evi1,
GATA ... potential protein binding sites for the REBP, AML1, AP1, Sp1, and MZF1 ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Charge movement and transcription regulation of L-type calcium channel a 1S in skeletal muscle cells
Z Zheng, ZM Wang, O Delbono - jp.physoc.org
... deletion (see below). The CG-repeat sequence (CCCAGCCC), found at position
_148 to _139 represents a binding site for SP1. GATA-2 ...
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cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase - Full text - MIT Libraries
Y Hirahara, M Tsuda, Y Wada, K Honke - European Journal of Biochemistry, 2000 - ejbiochem.org
... The upstream regions of exons 1c and 1g contain a GC box for Sp1 which is ... The upstream
region of exon 1f contains binding sites for CREB, SOX5, and SRY, which ...
Cited by 15 - Web Search - content.febsjournal.org - blackwell-synergy.com - ingentaconnect.com - all 7 versions »

Differentiation-dependent chromatin rearrangement coincides with activation of human papillomavirus … - Full text - MIT Libraries
LM del Mar Pena, LA Laimins - J Virol, 2001 - jvi.asm.org
... promoters appears to be mediated by transcription factors, such as Sp1, that presumably ...
the E7 ORF and identified in vitro binding of Oct-1, SOX5, and SRY (L ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on … - Full text - MIT Libraries
DC Ambrosetti, C Basilico, L Dailey - Mol Cell Biol, 1997 - mcb.asm.org
... Like- wise, ternary-complex formation and activation of the human immunodeficiency
virus type 1 enhancer by NF- B and Sp1 is abolished by base pair insertions ...
Cited by 93 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Regulation of the Orphan Nuclear Receptor Steroidogenic Factor 1 by Sox Proteins - Full text - MIT Libraries
HCS Jennifer, HA Ingraham - Molecular Endocrinology - mend.endojournals.org
... Limited studies have also implicated the CAAT-box and an SP1 site in the ... For example,
during chondrocyte differentiation, Sox5, Sox6, and Sox9 are proposed to ...
Cited by 1 - Web Search - mend.endojournals.org

Differentiation-Dependent Chromatin Rearrangement Coincides with Activation of Human Papillomavirus …
P work from Meyers… - milkpa.idv.tw
... promoters appears to be mediated by transcription factors, such as Sp1, that presumably ...
the E7 ORF and identified in vitro binding of Oct-1, SOX5, and SRY (L ...
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Spatially Precise DNA Bending Is an Essential Activity of the Sox 2 Transcription Factor - Full text - MIT Libraries
P Scaffidi, ME Bianchi - J Biol Chem, 2001 - jbc.org
... The Fgf4 enhancer, containing Sox2, Oct-3, and Sp1 binding sites, was cloned in ... for
other HMG box transcription factors, such as SRY, LEF1, and Sox5 (8, 20, 21 ...
Cited by 15 - Web Search - jbc.org - southalabama.edu - ncbi.nlm.nih.gov

Oct-3/4 and Sox 2 Regulate Oct-3/4 Gene in Embryonic Stem Cells - Full text - MIT Libraries
S Okumura-Nakanishi, M Saito, H Niwa, F Ishikawa - J Biol Chem, 2005 - jbc.org
... 1C, bars 9–12) is consistent with the idea that the putative Sp1/Sp3 binding ... in EC
cells, and such related factors as Oct-1, Oct-6 or Sox5 cannot substitute ...
Cited by 3 - Web Search - jbc.org - ncbi.nlm.nih.gov

Turning on the male – SRY, SOX 9 and sex determination in mammals - Full text - MIT Libraries
KC Knower, S Kelly, VR Harley, F Alert - Cytogenetic and Genome Research, 2003 - content.karger.com
... This region also contains two defined SP1 binding sites that are capable of acting
as basal elements for the regulation of SRY expression (Desclozeaux et al ...
Cited by 9 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

National Academy of Clinical Biochemistry Guidelines for the Use of Tumor Markers in Testicular …
UH Stenman, R Lamerz, LH Looijenga, GJ Bosl - nacb.org
... 10 Other markers Although pregnancy-specific beta-1 glycoprotein (or SP1) and hCG
are both expressed in ... Consequently, SP1 is not routinely measured. ...
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