Myogenic basic helix–loop–helix proteins and Sp1 interact as components of a multiprotein … - Full text - MIT Libraries
E Biesiada, Y Hamamori, L Kedes, V Sartorelli - Mol Cell Biol, 1999 - mcb.asm.org
... Through the use of a combined gel mobility shift-Western blot technique, we first
demonstrate that cellular Sp1, SRF, and myogenin are all part of this ...
Cited by 35 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions - Full text - MIT Libraries
MD Roos, K Su, JR Baker, JE Kudlow - Mol. Cell. Biol, 1997 - mcb.asm.org
... serine 489 in Sp1 (Fig. 1). Thus, it appears that Sp1 and SRF differ in
the precise serines recognized by the O-GlcNAc transferase. ...
Cited by 64 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Sp1 represses IL-2 receptor alpha chain gene expression
DG Roman, MB Toledano, WJ Leonard - New Biol, 1990 - ncbi.nlm.nih.gov
... expression. In this study, the results of competition experiments suggest that
Sp1 and SRF compete for binding to the CArG region. Site ...
Cited by 10 - Web Search - Get it from MIT Libraries

Expression of the serum response factor gene is regulated by serum response factor binding sites. - Full text - MIT Libraries
JA Spencer, RP Misra - J Biol Chem, 1996 - jbc.org
... We are currently investigating further the nature of Sp1 and SRF interactions and
their role in SRF promoter serum responsiveness as well as the role of zif ...
Cited by 37 - Web Search - jbc.org - ncbi.nlm.nih.gov

Interaction of CArG Elements and a GC-rich Repressor Element in Transcriptional Regulation of the … - Full text - MIT Libraries
CS Madsen, CP Regan, GK Owens - J Biol Chem, 1997 - jbc.org
... Furthermore, unlike other factors shown to inhibit SRF activity, gel-shift analysis
of Sp1 and SRF binding to the juxtaposed GC-rich repressor and CArG-box2 ...
Cited by 24 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, …
V Sartorelli, KA Webster, L Kedes - Genes Dev, 1990 - genesdev.org
... Previously characterized sites interact with a protein identical with or related
to the serum response factor (SRF) at -100 and Sp1 at -70. ...
Cited by 78 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

YY 1 Is Regulated by O-Linked N-Acetylglucosaminylation(O-GlcNAcylation) - Full text - MIT Libraries
M Hiromura, CH Choi, NA Sabourin, H Jones, D … - J Biol Chem, 2003 - jbc.org
... 6B) as was found to be the case for the glycosylated forms of Sp1 and SRF. View
larger version (31K): [in this window] [in a new window], Fig. ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Role of transcription factor TFIIF in serum response factor-activated transcription - Full text - MIT Libraries
H Zhu, V Joliot, R Prywes - J Biol Chem, 1994 - jbc.org
... A low amount of TFIIF was sufficient for basal transcription, whereas higher
amounts were required for SRF, but not Sp1, activation. ...
Cited by 25 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells - Full text - MIT Libraries
D Freyssenet, I Irrcher, MK Connor, M Di Carlo, DA … - Am J Physiol Cell Physiol, 2004 - intl-ajpcell.physiology.org
... A23187 also increased Egr-1, SRF and Sp1 protein expression, ... Time-dependent changes
in Sp1, SRF, and Tfam protein expression following A23187 treatment. ...
Cited by 4 - Web Search - intl-ajpcell.physiology.org - ajpcell.physiology.org - ncbi.nlm.nih.gov - all 5 versions »

… granulosa cells by FSH and LH; combinatorial regulation by transcription factors CREB, SRF, Sp1, and … - Full text - MIT Libraries
DL Russell, KMH Doyle, I Gonzales-Robayna, C … - Molecular Endocrinology, 2003 - mend.endojournals.org
... Egr-1 induction in rat granulosa cells by FSH and LH; combinatorial regulation
by transcription factors CREB, SRF, Sp1, and Egr-1. ...
Cited by 1 - Web Search

An approach to identify over-represented cis-elements in related sequences - Full text - MIT Libraries
J Zheng, J Wu, Z Sun - Nucleic Acids Research, 2003 - nar.oupjournals.org
... promoters, most of the copies of MEME Motif-2 and Motif-3 were covered by the putative
cis-elements detected with the matrices for Sp1 and SRF, respectively. ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Basic fibroblast growth factor activates serum response factor gene expression by multiple distinct … - Full text - MIT Libraries
JA Spencer, ML Major, RP Misra - Mol Cell Biol, 1999 - mcb.asm.org
... Support for the idea that Sp1 and SRF can exist in a complex has come from our
observation that SRF and Sp1 can associate in vivo, as determined in a yeast two ...
Cited by 9 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Regulation of Egr-1, SRF, and Sp1 mRNA expression in contracting skeletal muscle cells - Full text - MIT Libraries
I Irrcher, DA Hood - J Appl Physiol, 2004 - jap.org
... The mRNA expression of Sp1 and SRF in response to contractile activity differed
considerably from that of Egr-1. No change in Sp1 mRNA expression was observed ...
Cached - Web Search - jap.physiology.org - jap.physiology.org - ncbi.nlm.nih.gov - all 5 versions »

Composite regulatory elements: structure, function and classification.
S Receptor, HMG NF-kB, ETS SRF c-fos - Regulation - gene-regulation.com
... C00185. CEs containing binding sites for ETS and MADS factors. ETS, SRF, c-fos,
human egr-1, mouse. ... Oct-2A, lymphoid-specific. Sp1, ubiquitous Oct-1, ubiquitous. ...
Cached - Web Search - Get it from MIT Libraries

In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... Position 800 to 700 Lyf-1, Sp1, SRF SRF, Kr MEF-2 En, Sp1, GCF, ANF, ... Sp1 ODC1, (4
copies), RXR , Olf-1 XPF-1 400 to 300 Sp1 D1, SRF, Sp1 SRF, SRF, Sp1 SRF, ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Myocardial activation of the human cardiac alpha-actin promoter by helix-loop-helix proteins. - Full text - MIT Libraries
V Sartorelli, NA Hong, NH Bishopric, L Kedes - Proc Natl Acad Sci US A, 1992 - pubmedcentral.nih.gov
... The same DNA sequence elements recognized by SRF, Sp1, and MyoD and required for
HCA transcription in skeletal muscle cells were also found to be necessary for ...
Cited by 31 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Smooth Muscle-Specific Transcription Without a CArG Box Element - Full text - MIT Libraries
MW Majesky - Circulation Research, 2002 - circres.ahajournals.org
... of the cardiac -actin promoter in skeletal muscle cells was shown to depend upon
a muscle-specific multiprotein complex containing myogenin, Sp1, and SRF. ...
Cited by 1 - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov

The hardwiring of development: organization and function of genomic regulatory systems - Full text - MIT Libraries
MI Arnone, EH Davidson - Development, 1997 - dev.biologists.org
... YY1 MAPF SRF MEF2 MDF MDF MDF HD MDF MAPF MDF MDF MEF2 SRF HF1 SRF SRF SRF MDF SRF
MDF SRF SRF YY1 TEF1 SP1 SP1 SRF TEF1 TEF1 SP1 TATA TATA TATA TATA +1 +1 +
Cited by 258 - Web Search - ipef.br - wwwlib.bionet.nsc.ru - bioinformatics.buffalo.edu - all 8 versions »

Differential patterns of human cytomegalovirus gene expression in various T-cell lines carrying …
Z Beck, A Bacsi, X Liu, P Ebbesen, I Andirko, E … - Journal of Medical Virology, 2003 - doi.wiley.com
... The mouse MAb to ATF-1 and rabbit affinity-purified polyclonal antibodies
to SP1 and SRF were also from Santa Cruz Biotechnology. ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Sporogen, S14–95 and S-curvularin, three inhibitors of human inducible nitricoxide synthase … - Full text - MIT Libraries
Y Yao, M Hausding, G Erkel, T Anke, U Forstermann, … - Mol Pharmacol, 2003 - molpharm.aspetjournals.org
... for transcription factors such as AP-1, C/EBP, c-ETS-1, CREB, GATA, IRF-1, NF-1,
NFAT, NF- B, NF-IL6, Oct-1, PEA3, p53, Sp1, SRF, and STAT1 (GenBank AC005697). ...
Cited by 4 - Web Search - molpharm.aspetjournals.org - ncbi.nlm.nih.gov

Electrical activity regulates AChR gene expression via JNK, PKCj and Sp1 in skeletal chick muscle
N Altiok, JP Changeux - pasteur.fr
... has been shown that activation of the human car- diac K-actin promoter in skeletal
muscle requires the integrity of DNA binding sites for the SRF, Sp1 and for ...
View as HTML - Web Search

Interaction with RAP 74 subunit of TFIIF is required for transcriptional activation by serum … - Full text - MIT Libraries
V Joliot, M Demma, R Prywes - Nature, 1995 - nature.com
... to support SRF-activated transcription in vitro but has little effect on the protein's
basal transcription activity or its ability to support SP1-activated ...
Cited by 45 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

M-CAT, CarG and Sp1 elements are required for 1-adrenergic induction of the skeletal-actin promoter … - Full text - MIT Libraries
LR Karns, K Kariya, PC Simpson - J. Biol. Chem, 1995 - jbc.org
... target for -adrenergic signaling at the skACT promoter, or whether the SRF is simply ...
promoter fragment (-155/-76) containing a CArG and a putative Sp1 site did ...
Cited by 8 - Web Search - jbc.org

Regulation of MCL 1 through a Serum Response Factor/Elk-1-mediated Mechanism Links Expression of a … - Full text - MIT Libraries
KJ Townsend, P Zhou, L Qian, CK Bieszczad, CH … - J Biol Chem, 1999 - dx.doi.org
... Serum response factor (SRF), Elk-1, and Sp1 bound to cognate sites within this segment,
SRF and Elk-1 acting coordinately to affect both basal activity and TPA ...
Cited by 31 - Web Search - jbc.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1 - Full text - MIT Libraries
S Sif, TD Gilmore - J. Virol, 1994 - pubmedcentral.nih.gov
... The v-Rel oncoprotein increases expression from Sp1 site-containing promoters in
chicken ... binds to NF-kappa B p50 and serum response factor (SRF) and associates ...
Cited by 20 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

p21WAF1/CIP1 is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a … - Full text - MIT Libraries
J Adnane, FA Bizouarn, Y Qian, AD Hamilton, SM … - Mol. Cell. Biol, 1998 - mcb.asm.org
... and Sp1-Responsive Element: Involvement ... Electrophoretic mobility shift assays showed
a small increase in the amount of DNA-bound Sp1-Sp3 complexes. ...
Cited by 64 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Role of Sp1 in insulin regulation of gene expression
SL Samson, NC Wong - J. Mol. Endocrinol, 2002 - journals.endocrinology.org
... Solomon SS, Palazzo MR, Takahashi T & Raghow R. 1997 Transcription factor Sp1 is
necessary ... 1999 Expression of the SRF gene occurs through a Ras/Sp/SRF-mediated ...
Cited by 14 - Cached - Web Search - dx.doi.org - jme.endocrinology-journals.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Eukaryotic Regulatory Element Conservation Analysis and Identification Using Comparative Genomics - Full text - MIT Libraries
Y Liu, XS Liu, L Wei, RB Altman, S Batzoglou - Genome Research, 2004 - genome.org
... 15/2/11 From the 28 human-muscle-specific genes, CompareProspector correctly identified
the MYF, MEF2, SP1, and SRF motifs out of six known transcription-factor ...
Cited by 16 - Web Search - gremlin1.zool.iastate.edu - ai.stanford.edu - dx.doi.org - all 13 versions »

Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter - Full text - MIT Libraries
F Galvagni, S Capo, S Oliviero - J. Mol. Biol, 2001 - unisi.it
... by adding speci®c antibody for Sp1 (lanes 3, 7 and 11) or Sp3 (lanes 4, 8 and 12)
to the reaction mixture. The unrelated (unr) antibody anti-SRF did not ...
Cited by 24 - Web Search - unisi.it - ncbi.nlm.nih.gov - all 4 versions »

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor … - Full text - MIT Libraries
SV Subramanian, JA Polikandriotis, RJ Kelm Jr, JJ … - Mol. Biol. Cell, 2004 - pubmedcentral.nih.gov
... may be related to differences in the levels of native Pur proteins and/or availability
of SMA enhancer activating factors such as Sp1, TEF1, or SRF in each ...
Cited by 2 - Web Search - ijmm.org - ncbi.nlm.nih.gov

Expression of the smooth muscle myosin heavy chain gene is regulated by a negative-acting GC-rich … - Full text - MIT Libraries
CS Madsen, JC Hershey, MB Hautmann, SL White, GK … - J Biol Chem, 1997 - jbc.org
... The Sp1, Sp3, SRF, and CTF/NF1 antibodies used for EMSA supershift experiments
were all purchased commercially (Santa Cruz). EMSA ...
Cited by 60 - Web Search - jbc.org - ncbi.nlm.nih.gov

Rho GTPases as Modulators of the Estrogen Receptor Transcriptional Response - Full text - MIT Libraries
LF Su, R Knoblauch, MJ Garabedian - J Biol Chem, 2001 - jbc.org
... To determine whether Rho GDI-mediated activation is specific to steroid receptors,
we tested the effect of Rho GDI on Sp1- and SRF-dependent transactivation. ...
Cited by 21 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Induction of Vascular Smooth Muscle {alpha}-Actin Gene Transcription in Transforming Growth Factor { …
M Editor, CH Heldin - molbiolcell.org
... may be related to differences in the levels of native Pur proteins and/or availability
of SMA enhancer activating factors such as Sp1, TEF1, or SRF in each ...
Web Search - molbiolcell.org

SRF protein is upregulated during stretch-induced hypertrophy of rooster ALD muscle - Full text - MIT Libraries
M Flueck, JA Carson, RJ Schwartz, FW Booth - J Appl Physiol, 1999 - jap.org
... Home page I. Irrcher and DA Hood Regulation of Egr-1, SRF, and Sp1 mRNA expression
in contracting skeletal muscle cells J Appl Physiol, December 1, 2004; 97(6 ...
Cited by 19 - Cached - Web Search - jap.physiology.org - jap.org - ncbi.nlm.nih.gov - all 5 versions »

Organization and myogenic restricted expression of the murine serum response factor gene - Full text - MIT Libraries
NS Belaguli, LA Schildmeyer, RJ Schwartz - J. Biol. Chem, 1997 - jbc.org
... A and B show binding of SRF and Sp1 from myotube nuclear extracts to cognate probes. ...
Sp1 Binding Activity Is Required for SRF Promoter Activity ...
Cited by 61 - Web Search - jbc.org - ncbi.nlm.nih.gov

Regulation of SRF Activity by Rho Family GTPases
R TREISMAN, AS ALBERTS, E SAHAI - Cold Spring Harbor Symposia on Quantitative Biology, 1998 - dx.doi.org
... 1994) and cooperate with the SRF carboxy-terminal activation domain to activate
transcription (Hill et al. ... Regulation of SRF Activity by Rho Family GTPases ...
Cited by 21 - Web Search - cshl-symposium.org - cshl-symposium.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer - Full text - MIT Libraries
L Wang, D Wei, S Huang, Z Peng, X Le, TT Wu, J Yao … - Clin Cancer Res, 2003 - intl-clincancerres.aacrjournals.org
... [Abstract/Free Full Text]; Sorensen P., Wintersberger E. Sp1 and NF-Y ... [Abstract/Free
Full Text]; Spencer JA, Misra RP Expression of the SRF gene occurs through a ...
Cited by 11 - Web Search - intl-clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

… transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF … - Full text - MIT Libraries
B Cen, A Selvaraj, RC Burgess, JK Hitzler, Z Ma, … - Mol Cell Biol, 2003 - mcb.asm.org
... In addition, SRF binds and functionally cooperates with several other transcriptional
factors, including Sp1, C/EBPß, and TFII-I (24, 33, 52, 54). ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - columbia.edu - dx.doi.org - all 7 versions »

Muscle actin genes: A first step towards computational classification of tissue specific promoters - Full text - MIT Libraries
K Frech, K Quandt, T Werner - In Silico Biology, 1998 - iospress.metapress.com
... SRF - TATA 0.005 0.245 1: 53.761 SRF - SP1 0.019 0.694 1: 35.712 MyoD -
MEF2 0.154 0.449 1: 2.925 CEBP - MyoD 0.167 0.449 1: 2.685 ...
Cited by 41 - Web Search - bioinfo.de - bioinfo.de - ncbi.nlm.nih.gov - all 5 versions »

Prediction of C regulatory elements using statistical analysis.
P Qiu, W Ding, Y Jiang, J Greene, L Wang - ScientificWorldJournal, 2002 - thescientificworld.com
... By this approach, we have been able to Page 2. confirm quite some, for example
Pbx and Oct-1, C/EBP and SRF, YY1 and NF-AT, EGR and SP1 etc. ...
Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Computational analysis of composite regulatory elements - Full text - MIT Libraries
P Qiu, W Ding, Y Jiang, JR Greene, L Wang - Mammalian Genome, 2002 - springerlink.com
... 24.7 NF1 NFY 490.5 Oct-1 TCF11 123.3 MEF2 TATA 45.9 ELK1 SP1 24.6 CREB XBP1
454.6 SRF YY1 123.0 MZF1 NFKB 45.6 CDP PBX1 24.3 CEBPB ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

Influence of promoter potency on the transcriptional effects of YY 1, SRF and Msx-1 in transient … - Full text - MIT Libraries
T Lee, ME Bradley, JL Walowitz - Nucleic Acids Research, 1998 - nar.oupjournals.org
... mediating transrepression, which essentially rules out protein factors such as Sp1,
YAF2 and ... which have been shown to interact with YY1 and SRF respectively (34 ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Transforming growth factor-beta response elements of the skeletal alpha- actin gene. Combinatorial … - Full text - MIT Libraries
WR MacLellan, TC Lee, RJ Schwartz, MD Schneider - J Biol Chem, 1994 - jbc.org
... role of YY1 as an inhibitor of SRF effects. However, efficient SkA transcription
requires combinatorial action of SRE1 with consensus sites for Sp1 and the ...
Cited by 88 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Effect of ecteinascidin-743 on the interaction between DNA binding proteins and DNA - Full text - MIT Libraries
M Bonfanti, E La Valle, JMFS Faro, G Faircloth, G … - Anti-Cancer Drug Design, 1999 - ingentaconnect.com
... transcriptional activators regulated during the cell cycle (E2F) or growth stimulation
by serum (SRF); and (iii) general transcription factors (TBP, Sp1 and NF ...
Cited by 31 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Multiple Sp1 Binding Sites in the Cardiac/Slow Twitch Muscle Sarcoplamsic Reticulum Ca-ATPase Gene … - Full text - MIT Libraries
DL Baker, V Dave, T Reed, M Periasamy - Mol. Cell. Biol, 2004 - intl.jbc.org
... For example, the cardiac -actin gene has been shown to require Sp1 in addition to
MyoD1 and an SRF-like factor for muscle-specific gene expression(41) . ...
Cited by 1 - Web Search - intl.jbc.org

Specific inhibition of skeletal alpha-actin gene transcription by applied mechanical forces through … - Full text - MIT Libraries
AM Lew, M Glogauer, CA McUlloch - Biochem J, 1999 - biochemj.org
... TEF-1 and YY1 caused significant (P 0.01) increases in luciferase activity,
whereas SRF and SP1 caused signficant decreases (P 0.01). ...
Cited by 19 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification of multiple proteins that interact with functional regions of the human cardiac alpha … - Full text - MIT Libraries
TA Gustafson, L Kedes - Mol. Cell. Biol, 1989 - pubmedcentral.nih.gov
... SRF. SRF was found to bind to the remaining three CArG boxes, two of which
were closely interdigitated with Sp1 sites. In addition ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification of sparsely distributed clusters of cis-regulatory elements in sets of co-expressed … - Full text - MIT Libraries
G Kreiman - Nucleic Acids Research, 2004 - nar.oupjournals.org
... An example of the results obtained is shown in Figure 3. This module, formed by
SP1, SRF, TEF and another putative motif, locates the known regulatory regions ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - ramonycajal.mit.edu - ingentaconnect.com - all 10 versions »

Displacement of BrdUrd-Induced YY1 by Serum Response Factor Activates Skeletal {alpha}-Actin … - Full text - MIT Libraries
T Lee, Y Shi, RJ Schwartz - Proceedings of the National Academy of Sciences - pnas.org
... KA Youker, ML Entman, and RJ Schwartz Inhibitory Cardiac Transcription Factor,
SRF-N, Is ... XP Dong and H. Pfister Overlapping YY1- and aberrant SP1-binding sites ...
Cited by 40 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

AG/C Element Mediates Repression of the SM22 {alpha} Promoter Within Phenotypically Modulated Smooth … - Full text - MIT Libraries
BR Wamhoff, MH Hoofnagle, A Burns, S Sinha, OG … - Circulation Research, 2004 - circresaha.org
... that Sp1 does not alter SRF binding to CArG boxes, there is lack of direct evidence
for this mechanism and the involvement of Sp1 regulation of SRF binding to ...
Cited by 2 - Cached - Web Search - circres.ahajournals.org - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »