Physical and Functional Interactions between USF and Sp 1 Proteins Regulate Human Deoxycytidine … - Full text - MIT Libraries
Y Ge, TL Jensen, LH Matherly, JW Taub - J Biol Chem, 2003 - jbc.org
... In Sp- and USF-null Dro- sophila Mel-2 cells, both Sp1 and USF1 stimulated dCK promoter
activity in a dose-dependent manner, how- ever, both Sp3 and USF2a were ...
Cited by 9 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

The roles of Sp1, Sp3, USF1/USF2 and NRF-1 in the regulation and three-dimensional structure of the … - Full text - MIT Libraries
D KUMARI, A GABRIELIAN, D WHEELER, K USDIN - Biochem. J, 2005 - biochemj.org
... The roles of Sp1, Sp3, USF1/USF2 and NRF-1 in the regulation and three-dimensional
structure of the Fragile X mental retardation gene promoter. ...
Cited by 1 - Cached - Web Search - biochemj.org - ncbi.nlm.nih.gov

Occupancy and synergistic activation of the FMR 1 promoter by Nrf-1 and Sp 1 in vivo - Full text - MIT Libraries
KT Smith, B Coffee, D Reines - Human Molecular Genetics, 2004 - hmg.oupjournals.org
... We tested the activity of five such candidate transcription factors, Sp1, USF1 and
2, Max and Nrf-1, by co-transfecting expression vectors encoding the human ...
Cited by 5 - Web Search - hmg.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Characterization of a Rat Neuronal Nicotinic Acetylcholine Receptor alpha 7 Promoter - Full text - MIT Libraries
U Nagavarapu, S Danthi, RT Boyd - J Biol Chem, 2001 - jbc.org
... ice. The Sp1, USF1, and USF2 supershifting antibodies were purchased from
Santa Cruz Biotechnology, Inc (Santa Cruz, CA). Some of ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov

Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate … - Full text - MIT Libraries
M Liu, JR Whetstine, SG Payton, Y Ge, RM Flatley, … - Biochem. J, 2004 - biochemj.org
... a null background for both these transcription factors [30]. Sp1, USF1, and ... interest,
the transactivating effects of Sp1 and USF1 or USF2a were highly ...
Cited by 2 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cooperative E-box regulation of humanGLI 1 by TWIST and USF - Full text - MIT Libraries
EH Villavicencio, JW Yoon, DJ Frank, EM … - genesis, 2002 - doi.wiley.com
... Here we report that the human GLI1 promoter is regulated by Sp1, USF1, USF2,
and Twist. The Twist gene encodes an exclusively nuclear ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Interaction of the transcription factors USF1, USF2, and (alpha)-PAL/Nrf-1 with the FMR1 promoter - Full text - MIT Libraries
D Kumari, K Usdin - J. Biol. Chem, 2001 - jbc.org
... purification. Antibodies against USF1, USF2, Max, c-Myc, Sp1, Sp3, Sp4, and
Egr-1 were from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). ...
Cited by 22 - Web Search - jbc.org - ncbi.nlm.nih.gov

Novel transcriptional regulation of the human CYP3A7 gene by Sp1 and Sp3 through nuclear factor … - Full text - MIT Libraries
T Saito, Y Takahashi, H Hashimoto, T Kamataki - J. Biol. Chem, 2001 - jbc.org
... 6B). HNF-3 , NF1, USF1, and Sp1/Sp3 as Proteins Binding to the Proximal Promoter
Region of the CYP3A7 Gene-- To identify the factors detected with the 136/ 99 ...
Cited by 24 - Web Search - jbc.org - ncbi.nlm.nih.gov

The roles of Sp1, Sp3, USF1/2 and NRF-1 in the regulation and 3 dimensional structure of the Fragile …
D Kumari, A Gabrielian, D Wheeler, K Usdin - biochemj.org
... 12- was published showing that Sp1 and USF1/2 interact [15]. ... combination with
Sp1 and USF1/2 which were already known to cause DNA bending, ...
View as HTML - Web Search - biochemj.org

Physical and Functional Interactions between USF and Sp1 Proteins Regulate Human Deoxycytidine … - Full text - MIT Libraries
KT Smith, B Coffee, D Reines, Y Ge, TL Jensen, ML … - J. Biol. Chem, 2003 - jbc.org
... In Sp- and USF-null Drosophila Mel-2 cells, both Sp1 and USF1 stimulated dCK promoter
activity in a dose-dependent manner, however, both Sp3 and USF2a were ...
Web Search

Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate …
C Hadjiagapiou, A Borthakur, RY Dahdal, RK Gill, J … - ajpgi.physiology.org
... Polyclonal antibodies against SP1, USF1, USF2, and MyoD proteins as well as USF
(5'-CACCCGGTCACGTGGCCTACACC-3') consensus oligonucleotide were purchased from ...
Web Search - ajpgi.physiology.org

Oligo GEArray® Human JAK/STAT Signaling Pathway Microarray
I Response, S Conditions - search.cosmobio.co.jp
... RNA polymerase II transcription factor activity: JUNB, MAF, MHC2TA, SP1, USF1.
Transcription coactivator activity: CREBBP, IL31RA, JUNB, MHC2TA, NCOA1, YY1. ...
View as HTML - Web Search

Transcriptional regulation of the cystathionine-beta-synthase gene in Down syndrome and non-Down … - Full text - MIT Libraries
Y Ge, TL Jensen, LH Matherly, JW Taub - Blood, 2003 - bloodjournal.org
... Competitions with unlabeled Sp1, USF1, or NF-Y consensus oligonucleotides were also
performed in CMK and CMS cells to confirm the identities of the specific ...
Cited by 5 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

Synergistic role of specificity proteins and upstream stimulatory factor 1 in transactivation of the … - Full text - MIT Libraries
T FURIHATA, M HOSOKAWA, T SATOH, K CHIBA - Biochem. J, 2004 - biochemj.org
... combination or the Sp1/USF1 combination (P<0.005). ... interact with the
Sp1/USF1 complex to further increase mCES2 promoter activity. ...
View as HTML - Web Search - dx.doi.org - bj.portlandpress.co.uk - ncbi.nlm.nih.gov - all 6 versions »

Characterization of a Rat Neuronal Nicotinic Acetylcholine Receptor 7 Promoter
U Nagavarapu, S Danthi, RT Boyd - jbc.org
... ice. The Sp1, USF1, and USF2 supershifting antibodies were purchased from
Santa Cruz Biotechnology, Inc (Santa Cruz, CA). Some of ...
Web Search

Oligo GEArray® Mouse JAK/STAT Signaling Pathway Microarray
I Response, S Conditions - search.cosmobio.co.jp
... factors and regulators: C2ta, Cebpb, Gata3, Hmga1, Ifnar2, Isgf3g, Junb, Mcm5, Myc,
Nr3c1, Sfpi1, Smad5, Smad6, Smad7, Smad9, Sp1, Usf1, Yy1 Genes Induced by ...
View as HTML - Web Search

AP-2 {alpha} selectively regulates fragile X mental retardation-1 gene transcription during … - Full text - MIT Libraries
JH Lim, AB Booker, T Luo, T Williams, Y Furuta, O … - Human Molecular Genetics, 2005 - hmg.oxfordjournals.org
... version (24K): [in this window] [in a new window], Figure 1. Human Fmr1 promoter
showing transcription binding sites (boxed; -Pal/Nrf1; AP-2; SP1; USF1/2; Max). ...
Web Search - hmg.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov

Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the adenomatous … - Full text - MIT Libraries
AS Jaiswal, S Narayan - J Cell Biochem, 2001 - doi.wiley.com
... less promoter and contains consensus binding sites for Octamer, AP2, Sp1, a CAAT ...
in several cancer cell lines and upstream stimulating factor-1 (USF1) and USF2 ...
Cited by 13 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Therapeutic potential of CPT I inhibitors: cardiac gene transcription as a target
M Focus, M Endocrine, D Delivery - Expert Opin. Investig. Drugs, 2002 - dx.doi.org
... fructose 6-P fructose 1.6-P pyruvate xylulose 5-phosphate Phosphatases, PP2a
Dephosphorylation of transcription factors like SP1, USF1, USF2 PDH CPT 1 CPT 2 ...
Web Search - ashley-pub.com - ashley-pub.com

Cellular zinc sensors: MTF-1 regulation of gene expression
GK Andrews - Biometals, 2001 - springerlink.com
... In these same samples there was no apparent change in protein- DNA interactions
with Sp1 or USF1 binding sites in this promoter (Dalton et al. 1996b). ...
Cited by 35 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate … - Full text - MIT Libraries
C Hadjiagapiou, A Borthakur, RY Dahdal, RK Gill, J … - Am J Physiol Gastrointest Liver Physiol, 2005 - ajpgi.physiology.org
... vectors encoding USF1 and 2 in Caco-2 cells and determining endogenous MCT1 expression
in USF2 overexpressed cells. The two potential SP1 binding sites found ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Mouse USF1 gene cloning: comparative organization within the c-myc gene family
AA Henrion, S Vaulont, M Raymondjean, A Kahn - Mammalian Genome, 1996 - springerlink.com
... located in the basic region is conserved across MiTF, USF2, and USF1 fac- tors. ... DNA
binding and regulatory effects of transcription factors SP1 and USF at the ...
Cited by 17 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Transcriptional regulation of the human cystathionine beta-synthase-1b basal promoter: synergistic … - Full text - MIT Libraries
Y Ge, MA Konrad, LH Matherly, JW Taub - Biochem. J, 2001 - biochemj.org
... basal promoter: synergistic transactivation by transcription factors NF-Y
and Sp1/Sp3 ... In SL2 cells, NF-Y and Sp1\Sp3 were synergistic. ...
Cited by 20 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast …
S Safe, M Wormke, I Samudio - J. Mammary Gland Biol. Neoplasia, 2000 - kluweronline.com
... can overlap cis elements required for estrogen action or can be 100 bases from these
elements; and AhR/Arnt interacts not only with ER but with Sp1, USF1/2 and ...
Cited by 17 - Web Search - springerlink.com - microvet.arizona.edu - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

A 69-Base Pair Fragment Derived from Human Transcobalamin II Promoter Is Sufficient for High … - Full text - MIT Libraries
N Li, B Seetharam - Journal of Biological Chemistry, 1998 - jbc.org
... mutagenesis studies with the 69-bp fragment demonstrated that a GC box ( 568/ 559)
and an E box ( 523/ 528), which interacted with Sp1/Sp3 and USF1/USF2 (where ...
Cited by 17 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Transcription factor activity of STAT proteins: structural requirements and regulation by … - Full text - MIT Libraries
T Decker, P Kovarik - Cellular and Molecular Life Sciences(CMLS), 1999 - springerlink.com
... Among transcription factors, AP1, c/EBP, IRF-1, NF-sB, Pu.1, Sp1 and USF1 co-operate
functionally, but direct protein contacts to STATs have not been shown. ...
Cited by 39 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Role of USF1 phosphorylation on cardiac alpha-myosin heavy chain promoter activity - Full text - MIT Libraries
Q Xiao, A Kenessey, K Ojamaa - Am J Physiol Heart Circ Physiol, 2002 - intl-ajpheart.physiology.org
... Therefore, phosphorylation of USF1 as well as other nuclear factors, including those
of ... Jun N-terminal kinase, c-Jun, serum response factor, and Sp1 in calcium ...
Cited by 6 - Web Search - ajpheart.physiology.org - ajpheart.physiology.org - ncbi.nlm.nih.gov - all 5 versions »

Role of USF 1 in the differential expression of the human deoxycytidine kinase gene in acute myeloid …
Y Ge, TL Jensen, DA Tatman, ML Stout, SA Buck, Y … - Leukemia, 2005 - nature.com
... Although USF1, USF2a and Sp1 proteins have all been suggested to be important for
dCK promoter activity, only USF1 transcripts significantly correlated with ...
Web Search - nature.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Upstream stimulatory factors, USF1 and USF2, bind to the human haem oxygenase-1 proximal promoter in … - Full text - MIT Libraries
TD HOCK, HS NICK, A AGARWAL - Biochem. J, 2004 - biochemj.org
... nuclear factor κB, AP-1 (activator protein-1), AP-2, Sp1 (stimulating protein-1 ... In
mammalian cells, two ubiquitously expressed genes, USF1 and USF2, have been ...
Cited by 2 - View as HTML - Web Search - biochemj.org - bj.portlandpress.co.uk - ncbi.nlm.nih.gov - all 5 versions »

TRANSCRIPTION FACTOR USF2 IS DEVELOPMENTALLY REGULATED IN FETAL LUNG AND ACTS TOGETHER WITH USF1 TO …
E Gao, Y Wang, JL Alcorn, CR Mendelson - ajplung.physiology.org
... Sp1; mutagenesis of any one of these sites severely reduces basal and cAMP stimulation
of SP-A promoter activity (39). Cooperative interaction of USF2/USF1 ...
Web Search - ajplung.physiology.org

The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene - Full text - MIT Libraries
L Zeng, H Liao, Y Liu, TS Lee, M Zhu, X Wang, MB … - Journal of Lipid Research, 2002 - jlr.org
... Point mutations in either Sp1 site or in the AP1 site had only a ... Preincubation of
nuclear extracts with antibodies established that USF1, USF2, and fos related ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

Contribution of Sp1 to initiation of transcription of angiotensinogen
B Jochimsen… - springerlink.com
... activity has biological and immunologi- cal similarity to USF1, a helix ... In promoters
containing TATA elements, Sp1 interacts with the transcription initiation ...
Web Search

Identification of Sterol-independent Regulatory Elements in the Human ATP-binding Cassette … - Full text - MIT Libraries
T Langmann, M Porsch-Oezcueruemez, S Heimerl, M … - J. Biol. Chem, 2002 - jbc.org
... In order to map the binding area in greater detail and to show whether Sp1, Sp3,
and USF1/2 bind to the Sp1 site and E-box, respectively, mutations were ...
Cited by 12 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

USF1 and USF2 Bind to the Human Heme Oxygenase-1 Proximal Promoter In Vivo and Regulate its …
TD Hock, HS Nick, A Agarwal, A Agarwal - biochemj.org
... of USF1 or USF2 enhances the basal expression of HO-1 and that expression of a ... kappa
B (NF-κB), activator protein-1 (AP-1), AP-2, Sp1, upstream stimulatory ...
View as HTML - Web Search

Characterization of the human liver fructose-1, 6-bisphosphatase gene promoter - Full text - MIT Libraries
B Herzog, M WALTNER-LAW, DK SCOTT, K ESCHRICH, DK … - Biochem J, 2000 - medschool.lsuhsc.edu
... Four of these sites bind to factors that activate FBP1 transcription (Sp1, Sp3,
USF1 and USF2), whereas one sitebindstoafactor(NF-κB)thatcanrepressFBP1 ...
Cited by 3 - View as HTML - Web Search - biochemj.org - medschool.lsumc.edu - ncbi.nlm.nih.gov - all 7 versions »

Regulation of the estrogen receptor α minimal promoter by Sp1, USF-1 and ERα - Full text - MIT Libraries
SAW Fuqua - Breast Cancer Research and Treatment, 2004 - kluweronline.com
... Report Regulation of the estrogen receptor α minimal promoter by Sp1, USF-1 and
ERα ... Key words: breast cancer, estrogen receptor, Sp1, transcription, USF-1 ...
Web Search - springerlink.com

CLONING, EXPRESSION, PURIFICATION AND CRYSTALLISATION OF THE HUMAN Ets-1/USF1/DNA COMPLEX & CRYSTAL …
FJ FERNENDEZ-PEREZ, P DOCTOR - tdx.cesca.es
... CLONING, EXPRESSION, PURIFICATION AND CRYSTALLISATION OF THE HUMAN Ets-1/USF1/DNA
COMPLEX & CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA HISTIDINOL-PHOSPHATE ... USF1. ...
Web Search

BD™ TransFactor Kits Data Sheet
TISOF BD, TKITT FACTORS, PP THP, PP THP - clontech.com
... Sp1 Sp1/Sp3 Raji 631935 1 631942 631936 Sp3 Sp1/Sp3 Raji 631942 STAT1 Stat1 U-937
(IFN-γ) 631935 1 STAT3 Stat3 HepG2 (IL6) 631953 631952 USF1 USF U-937 631937 ...
View as HTML - Web Search

BD™ TransFactor Kits Data Sheet
TISOFT KIT, T FACTORS, PP THP, PP THP - clontech.com
... Sp1 Sp1/Sp3 Raji 1 631934 631935 631942 631936 Sp3 Sp1/Sp3 Raji 631942 STAT1 Stat1
U-937 (IFN-γ) 1, 2 631917 631935 USF1 USF U-937 631937 USF2 USF U-937 ...
View as HTML - Web Search - bdbiosciences.com

The transcription factors MTF-1 and USF 1 cooperate to regulate mouse metallothionein-I expression … - Full text - MIT Libraries
GK Andrews, DK Lee, R Ravindra, P Lichtlen, M … - The EMBO Journal, 2001 - embojournal.npgjournals.com
... Rabbit polyclonal antisera against Sp1 (PEP 2), USF1 and USF2 were purchased from
Santa Cruz Biotechnology (Santa Cruz, CA) and antiserum against -fetoprotein ...
Cited by 29 - Web Search - emboj.org - nature.com - pubmedcentral.nih.gov - all 8 versions »

Participation of upstream stimulator factor(USF) in cadmium-induction of the mouse metallothionein-I … - Full text - MIT Libraries
Q Li, N Hu, MA Daggett, WA Chu, D Bittel, JA … - Nucleic Acids Research, 1998 - nar.oupjournals.org
... 2). The USF1 antisera had no effect on Sp1 binding complexes in the same nuclear
cell extracts (Fig. 2), nor did the USF2 antisera (data not shown). ...
Cited by 25 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Regulation of pdx-1 gene expression - Full text - MIT Libraries
D Melloul, S Marshak, E Cerasi - Diabetes, 2002 - diabetes.diabetesjournals.org
... Indeed, the transcription factors HNF-3ß, HNF-1 , HNF-1ß, SP1/3, USF1/2,
and PDX-1 itself regulate the expression of the pdx-1 gene. ...
Cited by 5 - Web Search - diabetes.diabetesjournals.org - ncbi.nlm.nih.gov

GC- and E-box Motifs as Regulatory Elements in the Proximal Promoter Region of the Neuronal … - Full text - MIT Libraries
C Carrasco-Serrano, A Campos-Caro, S Viniegra, JJ … - J Biol Chem, 1998 - jbc.org
... Antibodies specific for some proteins able to bind to GC-rich regions (Egr-1, Sp1,
AP2) or E-boxes (USF1, USF2, Max) were used to identify the factors ...
Cited by 9 - Web Search - jbc.org - ncbi.nlm.nih.gov

Novel transcriptional regulation of the human CYP3A7 gene by specificity protein (Sp) 1 and Sp3 … - Full text - MIT Libraries
T Saito, Y Takahashi, H Hashimoto, T Kamataki - Mol. Pharmacol, 2004 - jbc.org
... Thus, we conclude that the expression of the CYP3A7 gene in HepG2 cells
is cooperatively regulated by Sp1, Sp3, HNF-3 and USF1. ...
Web Search

A Novel Factor Binding to the Glucose Response Elements of Liver Pyruvate Kinase and Fatty Acid … - Full text - MIT Libraries
J Hasegawa, K Osatomi, RF Wu, K Uyeda - J Biol Chem, 1999 - jbc.org
... 6), but none of the antibodies against USF1, Sp1, and c-Myc affected the
electrophoretic mobility of GRBP, suggesting that GRBP does not belong to any of ...
Cited by 29 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cellular import of cobalamin (vitamin B-12) - Full text - MIT Libraries
B Seetharam, S Bose, N Li - J Nutr, 1999 - nutrition.org
... is some evidence to suggest that physical interaction between Sp1 and the members
of the helix-loop-helix family of transcription factors, USF1/USF2, that bind ...
Cited by 11 - Web Search - nutrition.org - ncbi.nlm.nih.gov

Mini-Review Fragile X Mental Retardation Protein in Plasticity and Disease - Full text - MIT Libraries
PK Todd, JS Malter - Journal of Neuroscience Research, 2002 - doi.wiley.com
... analysis revealed four intereaction sites in the proximal 1.1 kb of the FMR1 promoter
that match consensus sequences for NRF1, Sp1, USF1, USF2, and c-myc. ...
Cited by 4 - Web Search - ntp.neuroscience.wisc.edu - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

c-Myc target gene specificity is determined by a post-DNAbinding mechanism - Full text - MIT Libraries
KE Boyd, J Wells, J Gutman, SM Bartley, PJ Farnham - Mol. Cell. Biol, 2005 - dx.doi.org
... We further demonstrate that although both Myc and USF1 can bind ... Transcriptional
Regulatory Complexes, Including E2F4, p107, p130, and Sp1, Control Fibroblast ...
Cited by 129 - Web Search - pnas.org - mcardle.oncology.wisc.edu - genomics.ucdavis.edu - all 10 versions »

A Role for Sp and Helix-Loop-Helix Transcription Factors in the Regulation of the Human Id 4 Gene … - Full text - MIT Libraries
A Pagliuca, P Cannada-Bartoli, L Lania - J Biol Chem, 1998 - jbc.org
... Conversely, USF1-mediated stimulation was not inhibited by Id4 co-expression. ... cells
showed that this repressor element is recognized by both Sp1 and Sp3 factors ...
Cited by 18 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Metal-responsive transcription factor-1 (MTF-1) selects different types of metal response elements …
Y Wang, I Lorenzi, O Georgiev, W Schaffner - Biol. Chem, 2004 - degruyter.com
... Some MREs in that promoter also contain overlapping/ adjacent binding sites for
other transcription factors, including Sp1, USF1 and nuclear factor-I (CTF-I/NF ...
Web Search - extenza-eps.com - degruyter.de - ncbi.nlm.nih.gov - all 8 versions » - Get it from MIT Libraries