Kruppel-like Factor 4 Abrogates Myocardin-induced Activation of Smooth Muscle Gene Expression - Full text - MIT Libraries
Y Liu, S Sinha, OG McDonald, Y Shang, MH Hoofnagle … - J Biol Chem, 2005 - jbc.org
... 2. Possible physical interaction between SRF and KLF4 was examined by
co-immunoprecipitation (IP) assay. The experiments were done ...
Cited by 1 - Web Search - dx.doi.org - ijmm.org - ncbi.nlm.nih.gov - all 5 versions »

A Transforming Growth Factor-{beta} Control Element Required for SM{alpha}-Actin Expression in Vivo … - Full text - MIT Libraries
Y Liu, S Sinha, G Owens - J Biol Chem, 2003 - jbc.org
... likely to involve complex combinatorial interactions of many cis-elements/transcription
factors including E-Box/E12/HEB, CArG/SRF/myocardin, and TCE/KLF4/KLF5. ...
Cited by 10 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A Transforming Growth Factor- Control Element Required for SM-Actin Expression in Vivo Also …
Y Liu, S Sinha, G Owens - Journal of Biological Chemistry - jbc.org
... Page 6. complex combinatorial interactions of many cis-elements/tran- scription
factors including E-Box/E12/HEB, CArG/SRF/myo- cardin, and TCE/KLF4/KLF5. ...
Web Search - Get it from MIT Libraries

Regulation of Smooth Muscle Phenotype - Full text - MIT Libraries
I Manabe, R Nagai - Current Science, 2003 - current-reports.com
Cited by 1 - Web Search - current-reports.com - biomedcentral.com - ncbi.nlm.nih.gov

Selective modulation of the SM22α promoter by the binding of BTEB3 to TGGG repeats
KM Martin, PD Ellis, JC Metcalfe, PR Kemp - biochemj.org
... to express multiple forms of SRF capable of binding and activating the SM22α ... factor
(GKLF/KLF4) bound to the SM22α promoter but transfection analysis showed ...
View as HTML - Web Search

Table 1. Transcription Factors Known or Likely to be Involved in Regulation of SMC Differentiation/ …
T Factor, MB Proteins, H Proteins, SMC Barx2b, KZF … - ahavj.ahajournals.org
... MADS Box Proteins, SRF, numerous SMC differentiation markers 4,6. MEF2B, SM MHC
101. ... Sp1/3, ACLP 12 ; ? SM MHC and SM22 95,107. GKLF/KLF4, SM22 and SM -actin 30. ...
Web Search

Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific … - Full text - MIT Libraries
JM Spin, S Nallamshetty, R Tabibiazar, EA Ashley, … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
... thought to suppress SM -actin (Klf4, Purb, Rbms1: patterns 3 and 4), while others
suppress neuronal growth (Hes1, Maged1, Ndn: all pattern 2). The SRF-CArG box ...
Cited by 1 - Web Search - physiolgenomics.physiology.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Selective modulation of the SM22alpha promoter by the binding of BTEB3 (basal transcription element- … - Full text - MIT Libraries
KM Martin, PD Ellis, JC Metcalfe, PR Kemp - Biochem. J, 2003 - biochemj.org
... Fully differentiated adult aortic VSMCs have been shown to express multiple forms
of SRF capable of binding and ... 8] showed that gut-enriched KLF (KLF4) bound to ...
Cited by 1 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

5'CArG degeneracy in smooth muscle {alpha}-actin is required for injury-induced gene suppression in … - Full text - MIT Libraries
JA Hendrix, BR Wamhoff, OG McDonald, S Sinha, T … - J. Clin. Invest, 2005 - jci.org
... and thus it will be interesting to determine whether KLF4 can mediate ... with other
regulatory mechanisms such as posttranslational modifications of SRF (36, 37 ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ijp-online.com - all 7 versions »

Molecular Determinants of Vascular Smooth Muscle Cell Diversity - Full text - MIT Libraries
JB Guest - Circulation Research, 2005 - circresaha.org
... of Elk-1, 45 KLF4-dependent downregulation of myocardin expression (Y. Liu and GK
Owens, unpublished data, 2004), and possible disruption of SRF binding to ...
Cached - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - circresaha.org - all 6 versions »

Patterns of Gene Expression Differentially Regulated by Platelet-derived Growth Factor and … - Full text - MIT Libraries
N Kaplan-Albuquerque, YE Bogaert, V Van Putten, MC … - J. Biol. Chem, 2005 - jbc.org
... with the array data, Western blotting showed that GKLF (KLF4) protein expression
was ... and expression is likely to be controlled through SRF-dependent pathways ...
Web Search - ncbi.nlm.nih.gov

Proteomic Profiling of Bone Marrow Mesenchymal Stem Cells upon Transforming Growth Factor{beta} 1 … - Full text - MIT Libraries
D Wang, JS Park, JSF Chu, A Krakowski, K Luo, DJ … - J Biol Chem, 2004 - jbc.org
... TCE element by decreasing KLF4 expression and increasing KLF5 expression (35–37).
In addition, TGF- enhances serum-response factor (SRF) expression/activity ...
Cited by 3 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL) - Full text - MIT Libraries
M Matsuoka - Retrovirology, 2005 - dx.doi.org
... and activates transcriptional pathways, such as NF-κB, AP-1 and SRF [8,17 ... while
hypermethylation silences transcription of the p16 [73], EGR3 and KLF4 genes as ...
Web Search - pubmedcentral.nih.gov - retrovirology.com - bmc.ub.uni-potsdam.de - all 10 versions »

Sp 1 and krueppel-like factor family of transcription factors in cell growth regulation and cancer - Full text - MIT Libraries
AR Black, JD Black, J Azizkhan-Clifford - Journal of Cellular Physiology, 2001 - doi.wiley.com
... includes the Sp proteins, Sp1, Sp2, Sp3, Sp4, and the ``kruÈppel- like factors''
(KLFs), EKLF (KLF1), LKLF (KLF2), BKLF/TEF-2(KLF3),GKLF/EZF(KLF4),IKLF/BTEB2 ...
Cited by 157 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Molecular regulation of vascular smooth muscle cell differentiation in development and disease - Full text - MIT Libraries
GK Owens, MS Kumar, BR Wamhoff - Physiol Rev, 2004 - physrev.physiology.org
... One of the most exciting recent discoveries was the identification of the serum
response factor (SRF) coactivator gene myocardin that appears to be required ...
Cited by 32 - Web Search - dx.doi.org - physrev.physiology.org - ncbi.nlm.nih.gov

Bone Morphogenetic Proteins in Vascular Calcification - Full text - MIT Libraries
LD Guest - Circulation Research, 2005 - circresaha.org
Institution: Google Indexer Sign In as Member/Individual
(Non-Member) Subscription Activation ...
Cached - Web Search - circres.ahajournals.org - circres.ahajournals.org - circresaha.org