Cooperative Transcriptional Activation by Serum Response Factor and the High Mobility Group Protein … - Full text - MIT Libraries
JA Spencer, MH Baron, EN Olson - J Biol Chem, 1999 - jbc.org
... 4. SSRP1 enhances SRF-CArG box interaction. A, gel mobility shift assays
were performed using in vitro translated SRF and Myc-SSRP1. ...
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catalytic subunits in Arabidopsis thaliana
T Mizoguchi, K Yamaguchi-Shinozaki, N Hayashida, H … - Plant Molecular Biology, 1993 - springerlink.com
... include DNA topoisomeraselI, RNA poly- merase I and II, oncoproteins (adenovirus
Ela and SV40 large T antigen) and transcription fac- tors (SRF, Myc, Fos, Myb ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Calcium/Calmodulin-dependent Protein Kinase Activates Serum Response Factor Transcription Activity … - Full text - MIT Libraries
IINCMG REGULATION, D HYPERTROPHY - J. Biol. Chem, 2003 - jbc.org
... In Vitro CaMK Phosphorylation of GST-SRF or Myc-HDAC4 —GST-SRF, Myc-HDAC4, or GST
alone (1 µg) was incubated in a kinase reaction buffer (50 mM HEPES, pH 7.4 ...
Cited by 14 - Web Search - faculty.biu.ac.il - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Cyclin E 2: a novel CDK 2 partner in the late G 1 and S phases of the mammalian cell cycle - Full text - MIT Libraries
N Lauper, ARP Beck, S Cariou, L Richman, K Hofmann … - Oncogene, 1998 - nature.com
... This promoter is responsive to an SRF-VP16 hybrid (Dalton and Treisman, 1992) or
to co-expression of an SRF-Myc bait and an interacting VP16-Max prey (Amati et ...
Cited by 40 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transactivation domains are not functionally conserved between vertebrate and invertebrate serum … - Full text - MIT Libraries
S Avila, MC Casero, R Fernandez-Canton, L Sastre - European Journal of Biochemistry, 2002 - ejbiochem.org
... Western blots and co-immunoprecipitations Expression of SRF-myc molecules in
transiently transfected cells was analyzed by Western blot. ...
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… , hydroperoxyoctadecadienoic acids, stimulate c-Fos, c-Jun, and c-Myc mRNA expression, mitogen- … - Full text - MIT Libraries
GN Rao, RW Alexander, MS Runge - J Clin Invest, 1995 - pubmedcentral.nih.gov
... Characterization of the phosphorylation of c-myc and c-jun proteins by an ... [PubMed]
[Full Text]; Marais R, Wynne J, Treisman R. The SRF accessory protein Elk-1 ...
Cited by 54 - Web Search - ncbi.nlm.nih.gov

SRF and MCM1 have related but distinct DNA binding specificities - Full text - MIT Libraries
J Wynne, R Treisman - Nucleic Acids Res, 1992 - pubmedcentral.nih.gov
... A protein domain conserved between yeast MCM1 and human SRF directs ternary ... Isolation
of monoclonal antibodies specific for human c-myc proto-oncogene product. ...
Cited by 26 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov

SignaTECT TM DNA-Dependent Protein Kinase Assay System
S Goueli, K Hsiao - promega.com
... factors including Fos, Jun, SRF, Myc, SP1, Oct-1, TFIID, E2F, the estrogen receptor,
and the large subunit of RNA Polymerase II (4,7). The ability of DNA-PK to ...
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Serum response factor promotes reepithelialisation and muscular structure restoration during gastric …
J CHAI, D BAATAR, AS TARNAWSKI - GASTROENTEROLOGY, 2004 - clinmed.med.ncku.edu.tw
... (A) A reverse-transcription polymer- ase chain reaction showing specific expression
of SRF transgene (SRF-myc) in the rat (Tg) injected with a SRF expres- sion ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

SignaTECT® DNA-Dependent Protein Kinase Assay System
BDNAPKA Protocol - promega.com
... protein RPA, heat shock protein hsp90, SV40 large T antigen (TAg of simian virus
40), a variety of transcription factors, including Fos, Jun, SRF, Myc, Sp1, Oct ...
Web Search

SignaTECT® DNA-Dependent Protein Kinase Assay System
I Description, IIP Components, VR Products, VI … - shpromega.cn
... protein RPA, heat shock protein hsp90, SV40 large T antigen (TAg of simian virus
40), a variety of transcription factors, including Fos, Jun, SRF, Myc, Sp1, Oct ...
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Actin dynamics control SRF activity by regulation of its coactivator MAL - Full text - MIT Libraries
F Miralles, G Posern, AI Zaromytidou, R Treisman - Cell, 2003 - uni-tuebingen.de
... with anti-myc beads (data not shown). ... tants thus represent specific inhibitors of
Rho-actin sig- naling, which act at the level of MAL rather than SRF. ...
Cited by 57 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A NF-kappa B/c-myc-dependent survival pathway is targeted by corticosteroids in immature thymocytes - Full text - MIT Libraries
W Wang, J Wykrzykowska, T Johnson, R Sen, J Sen - J. Immunol, 1999 - jimmunol.org
... Other factors, in particular those binding to a probe containing SRF/SP-1 binding ...
expression and decreased expression of the putative NF- B target gene, c-myc. ...
Cited by 23 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

MYC recruits the TIP 60 histone acetyltransferase complex to chromatin - Full text - MIT Libraries
SR Frank, T Parisi, S Taubert, P Fernandez, M … - EMBO Reports, 2003 - emboreports.npgjournals.com
... to Myc-induced H4 acetylation (Figs 2A, 4; Frank et al., 2001) and had RNA pol II
loaded onto their cap sites before MYC induction (SRF, unpublished data). ...
Cited by 28 - Web Search - nature.com - nature.com - ncbi.nlm.nih.gov - all 5 versions »

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle … - Full text - MIT Libraries
K Kimura, H Saga, K Hayashi, H Obata, Y Chimori, H … - Nucleic Acids Research, 1998 - nar.oupjournals.org
... factor is a chicken homolog of human MSSP-1 (c-myc gene single ... Serum response factor
(SRF) and essential transcriptional enhancer factor-1 (TEF-1), reported as ...
Cited by 7 - Web Search - nar.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 8 versions »

Induction of c 2 fos/c 2 myc expression by epidermal growth factor decreases with alteration of …
TJ Tong - Chinese Medical Journal, 1997 - age.bjmu.cn
... Our finding , the reduction of c2 myc expression in old cells , was contrast to
the ... 28 ,29 Recent stud2 ies showed that serum response factor (SRF) , a tran2 ...
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Functional domains of c-myc promoter binding protein 1 involved in transcriptional repression and … - Full text - MIT Libraries
AK Ghosh, R Steele, RB Ray - Mol. Cell. Biol, 1999 - mcb.asm.org
... The role of c-myc in cell growth ... Identification of transcriptional activation and
inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs ...
Cited by 9 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

The immunoglobulin heavy chain locus control region increases histone acetylation along linked c-myc … - Full text - MIT Libraries
L Madisen, A Krumm, TR Hebbes, M Groudine - Mol. Cell. Biol, 1998 - mcb.asm.org
... Nucleosomal structures of c-myc promoters with transcriptionally engaged RNA polymerase ...
Activation of SRF-regulated chromosomal templates by Rho-family GTPases ...
Cited by 50 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic … - Full text - MIT Libraries
M Affolter, J Montagne, U Walldorf, J Groppe, U … - Development, 1994 - dev.biologists.org
... large family of genes, including the proto-oncogenes c- fos, c-jun, c-myc and c ... The
vertebrate SRF is a DNA-binding protein that recog- nizes the SRE as a dimer ...
Cited by 41 - Web Search - wwwalt.med-rz.uni-sb.de - med-rz.uni-sb.de - ncbi.nlm.nih.gov - all 6 versions »

The serum response factor is extensively modified by phosphorylation following its synthesis in … - Full text - MIT Libraries
RP Misra, VM Rivera, JM Wang, PD Fan, ME Greenberg - Mol Cell Biol, 1991 - pubmedcentral.nih.gov
... activation of c-myc. Nature 312(5996):716–720. [PubMed]; Norman C, Runswick M, Pollock
R, Treisman R. Isolation and properties of cDNA clones encoding SRF, a ...
Cited by 31 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Influence of promoter potency on the transcriptional effects of YY 1, SRF and Msx-1 in transient … - Full text - MIT Libraries
T Lee, ME Bradley, JL Walowitz - Nucleic Acids Research, 1998 - nar.oupjournals.org
... SRF respectively (34,40), may be affected by high levels of YY1 or SRF proteins ... the
basal transcription machinery, as has been demonstrated for YY1 and c-Myc (41 ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Myocardial activation of the human cardiac alpha-actin promoter by helix-loop-helix proteins. - Full text - MIT Libraries
V Sartorelli, NA Hong, NH Bishopric, L Kedes - Proc Natl Acad Sci US A, 1992 - pubmedcentral.nih.gov
... that a member of the basic helix-loop-helix family, together with SRF and Sp1 ... A gene
with homology to the myc similarity region of MyoD1 is expressed during ...
Cited by 31 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

SRF and TEF-1 control of chicken skeletal a-actin gene during slow-muscle hypertrophy
JA CARSON, RJ SCHWARTZ, FW BOOTH - Am. J. Physiol, 1996 - ajpcell.physiology.org
Page 1. SRF and TEF-1 control of chicken skeletal ... Booth. SRF and TEF-1 control of
chicken skeletal cx-actin gene during slow-muscle hypertrophy. Am. J. Physiol. ...
Cited by 33 - Web Search - ajpcell.physiology.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

A role for VASP in RhoA-Diaphanous signalling to actin dynamics and SRF activity - Full text - MIT Libraries
R Grosse, JW Copeland, TP Newsome, M Way, R … - The EMBO Journal, 2003 - embojournal.npgjournals.com
... in the absence of cotransfected mDia1 proteins using either anti-myc or anti ... domains
required for this coincide with those required for SRF activation (Figure 8A ...
Cited by 9 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

MAD 1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation - Full text - MIT Libraries
G Poortinga, KM Hannan, H Snelling, CR Walkley, A … - The EMBO Journal, 2004 - embojournal.npgjournals.com
... UBF protein levels are regulated at the level of transcription in a manner
very similar to primary response genes such as SRF and c-MYC. ...
Cited by 5 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Myc is an essential negative regulator of platelet-derived growth factor beta receptor expression - Full text - MIT Libraries
SK Oster, WW Marhin, C Asker, LM Facchini, PA Dion … - Mol. Cell. Biol, 2000 - mcb.asm.org
... such as GATA-1, SRF, AP1, NF1, AP2, and NF-Y, and it is possible that one or all
of these sites are required to mediate the repression of pdgf- r mRNA by Myc. ...
Cited by 23 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Nuclear translocation of the SRF co-activator MAL in cortical neurons: role of RhoA signalling. - Full text - MIT Libraries
A Tabuchi, M Estevez, JA Henderson, R Marx, J … - Journal of Neurochemistry, 2005 - blackwell-synergy.com
... As it has been suggested that activation of the MAL/SRF pathway represents a ... 2005),
the myc-tagged Tech245 C construct used in these studies decreased the ...
Web Search - ncbi.nlm.nih.gov

N-Myc induction stimulated by insulin-like growth factor I through mitogen-activated protein kinase … - Full text - MIT Libraries
A Misawa, H Hosoi, A Arimoto, T Shikata, S Akioka, … - Cancer Res, 2000 - cancerres.aacrjournals.org
... to retinoid in morphological differentiation, tumorigenesis and N-myc expression
in ... 1995.[Abstract]; Marais R., Wynne J., Treisman R. The SRF accessory protein ...
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G3139, a Bcl-2 antisense oligodeoxynucleotide, may overcome drug resistance in VAD refractory …
SRF Stralen, A Hagenbeek, AC Bloem, HM Lokhorst - library.uu.nl
... of Bcl-2 in transgenic mice prolongs the life span of plasma cells and in combination
with abnormal expression of other oncogenes such as c-myc, contributes to ...
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Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced … - Full text - MIT Libraries
LG Larsson, F Bahram, H Burkhardt, B Luescher - Oncogene, 1997 - nature.com
... described for several transcription factors such as c- Jun, c-Myb, SRF, myogenin
and ... been suggested to be in operation for the regulation of the Myc/Max/Mad ...
Cited by 18 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

DYNAMIC O-LINKED GLYCOSYLATION OF NUCLEAR AND CYTOSKELETAL PROTEINS - Full text - MIT Libraries
GW Hart - Annual Review of Biochemistry, 1997 - biochem.annualreviews.org
... None of the four sites was anywhere near the primary casein kinase II phosphorylation
sites in p67 SRF . ... The c-myc oncoprotein is O-GlcNAcylated (20, 21). ...
Cited by 147 - Web Search - plant.annualreviews.org - soc.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

The RNA polymerase I transcription factor UBF is the product of a primary response gene. - Full text - MIT Libraries
M Glibetic, L Taylor, D Larson, R Hannan, B Sells, … - J Biol Chem, 1995 - jbc.org
... on assays and Northern blot analyses demonstrated that the UBF gene was a primary
response gene, exhibiting characteristics similar to those of c-myc and SRF. ...
Cited by 12 - Web Search - jbc.org - ncbi.nlm.nih.gov

Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation - Full text - MIT Libraries
K Tamura, B Hua, S Adachi, I Guney, J Kawauchi, M … - The EMBO Journal, 2005 - embojournal.npgjournals.com
... In this study, we could not determine the significance of the binding sites for
c-Myc, E2F, SRF, or AP1 in the ATF3 promoter, although the deletion of these ...
Web Search - pubmedcentral.nih.gov - embojournal.npgjournals.com

Point mutational analysis of the human c-fos serum response factor binding site - Full text - MIT Libraries
S Leung, NG Miyamoto - Nucleic Acids Res, 1989 - pubmedcentral.nih.gov
... c-fos transcription observed in serum-deprived cells is mediated through SRF binding
to ... c-fos gene and protein by growth factors precedes activation of c-myc. ...
Cited by 14 - Web Search - nar.oupjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Proteolytic Regulation of the Zinc Finger Transcription Factor YY 1, a Repressor of Muscle- … - Full text - MIT Libraries
JL Walowitz, ME Bradley, SJ Chen, TC Lee - J Biol Chem, 1998 - jbc.org
... of simultaneously activating and repressing the expression of the c-myc proto-oncogene ...
transcription of the skeletal -actin gene by excluding SRF, a positive ...
Cited by 20 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor - Full text - MIT Libraries
LM Boxer, R Prywes, RG Roeder, L Kedes - Mol Cell Biol, 1989 - pubmedcentral.nih.gov
... Furthermore, immune serum raised against the c-fos SRF also recognized the actin
CBF. ... is accompanied by the rapid induction of c-fos and c-myc proto-oncogenes. ...
Cited by 44 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein … - Full text - MIT Libraries
N Semova, B Kapanadze, M Corcoran, A Kutsenko, A … - Genomics, 2003 - biocristalografia.df.ibilce.unesp.br
... protein that selec- tively recognized the second ISRE in the MYC promoter and ... 174,
and 187), nuclear factor Y ( 93), serum response factor (SRF) ( 105), Wilms ...
View as HTML - Web Search - gmu.edu - ncbi.nlm.nih.gov - all 4 versions »

Mutation of serum response factor phosphorylation sites and the mechanism by which its DNA-binding … - Full text - MIT Libraries
JR Manak, R Prywes - Mol Cell Biol, 1991 - pubmedcentral.nih.gov
... synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin ... Treisman
R. Isolation and properties of cDNA clones encoding SRF, a transcription ...
Cited by 25 - Web Search - virologyj.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulation of the Human c-fos Gene: X-ray Structure of the SAP-1, SRF, DNA Ternary Complex
DN ETH - e-collection.ethbib.ethz.ch
... 14435 Regulation of the Human c-fos Gene: X-ray Structure of the SAP-1, SRF, ... protein
complex at the SRE comprising a homo-dimer of serum response factor (SRF) ...
View as HTML - Web Search - e-collection.ethbib.ethz.ch

Identification of serum-inducible genes: different patterns of gene regulation during G0→ S and G1 … - Full text - MIT Libraries
M Wick, C Burger, S Brusselbach, FC Lucibello, R … - J Cell Sci, 1994 - jcs.biologists.org
... Many genes of the IE response encode transcription factors belonging to the AP-1,
NFκB, SRF and Myc families and in some cases the functional significance of ...
Cited by 32 - Web Search - jcs.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Identification of a CArG Box-Dependent Enhancer within the Cysteine-Rich Protein 1 Gene That Directs … - Full text - MIT Libraries
B Lilly, EN Olson, MC Beckerle - Developmental Biology, 2001 - ncbi.nlm.nih.gov
... regulatory programs within SMCs and suggest a role for SRF in the ... Smooth,
Vascular/metabolism*; Mutation; Nuclear Proteins*; Proto-Oncogene Proteins c-myc/ ...
Cited by 17 - Web Search

Expression and activity of serum response factor is required for expression of the muscle- … - Full text - MIT Libraries
C Gauthier-Rouviere, M Vandromme, D Tuil, N … - Mol Biol Cell, 1996 - pubmedcentral.nih.gov
... R, Treisman R. Isolation and properties of cDNA clones encoding SRF, a transcription ...
MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert ...
Cited by 24 - Web Search - molbiolcell.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Effect of ecteinascidin-743 on the interaction between DNA binding proteins and DNA - Full text - MIT Libraries
M Bonfanti, E La Valle, JMFS Faro, G Faircloth, G … - Anti-Cancer Drug Design, 1999 - ingentaconnect.com
... types of factors: (i) oncogene products such as MYC, c-MYB and Maf; (ii) trans-
criptional activators regulated during the cell cycle as E2F and SRF; and (iii ...
Cited by 31 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The cellular and molecular response of cardiac myocytes to mechanical stress
J Sadoshima, S Izumo - Annu Rev Physiol, 1997 - physiol.annualreviews.org
... early genes such as c-fos, c-jun, Egr-1, and c-myc (38, 74). ... that the signal generated
by mechanical stretch activates the serum response factor (SRF)-p62 TCF ...
Cited by 266 - Web Search - physiol.annualreviews.org - phyto.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Primer Pairs for Neurotrophic Factors & β-Actin
P Neurosciences - EMBO J - shpromega.cn
... SV40 large T antigen, the estrogen receptor, RNA polymerase II large subunit and
a variety of other transcription factors (eg, Fos, Jun, SRF, Myc, Sp1, Oct-1 ...
View as HTML - Web Search - shpromega.com.cn - promega.com - Get it from MIT Libraries

Neonatal induction of a nuclear protein that binds to the c-fos enhancer. - Full text - MIT Libraries
BZ Levi, JW Kasik, PA Burke, R Prywes, RG Roeder, … - Proc Natl Acad Sci US A, 1989 - pubmedcentral.nih.gov
... The band III factor was indistinguishable from the SRF in all criteria tested. ... of
c-fos gene and protein by growth factors precedes activation of c-myc. ...
Cited by 1 - Web Search - pnas.org - ncbi.nlm.nih.gov

Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal a-actin transcription …
TEC LEE, Y SHIt, RJ SCHWARTZ - Cell, 1992 - pnas.org
... ABSTRACT Muscle-restricted transcription oftheskeletal a-actin gene is controlled
in partby a positive regulator, serum response factor (SRF), and a negative ...
Cited by 18 - Web Search - Get it from MIT Libraries

Induction of Early Growth Response Gene Egr2 by Basic Calcium Phosphate Crystals through a Calcium- …
FTC Alert, AW English, G Atlanta - Cells Tissues Organs, 2003 - content.karger.com
... that induced Egr2 could stimulate the activities of several transcription factors
that are associated with cell proliferation, such as c-fos, SRF and c-myc. ...
Cited by 1 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Vav 1 Couples T Cell Receptor to Serum Response Factor-dependent Transcription via a MEK-dependent … - Full text - MIT Libraries
C Charvet, P Auberger, S Tartare-Deckert, A … - J Biol Chem, 2002 - jbc.org
... were stimulated and analyzed as in panel A. Lysates were analyzed for Vav1 and SRF
mutant expression by immunoblotting with anti-Myc and anti-HA antibodies. ...
Cited by 15 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Unique Features of the Mode of Action of ET-743 - Full text - MIT Libraries
M D'Incalci, E Erba, G Damia, E Galliera, L … - The Oncologist, 2002 - theoncologist.alphamedpress.org
... Y. No inhibition of DNA binding was found for Sp1, Maf, MYB, or MYC, while for TBP,
E2F, and SRF, inhibition was observed at concentrations higher than 50 µM. ...
Cited by 12 - Web Search - dx.doi.org - theoncologist.alphamedpress.org - ncbi.nlm.nih.gov