Lipopolysaccharide Stimulates p 38-dependent Induction of Antiviral Genes in Neutrophils … - Full text - MIT Libraries
KC Malcolm, GS Worthen - J Biol Chem, 2003 - jbc.org
... transcription factors, including activating transcription factor-2, SRF accessory
protein-1 ... to the phosphorylation of the STAT1 and STAT2 transcription factors ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

STAT proteins and transcriptional responses to extracellular signals - Full text - MIT Libraries
CM Horvath - Trends Biochem Sci, 2000 - chosun.ac.kr
... TFII-I also binds to the serum-response factor (SRF) and DNA, potentially ... screening
of cDNA libraries and sequence databases for homologues of STAT1 and STAT2. ...
Cited by 93 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B ...
MMP3, MST1, NPPB, NOS3, OAS1, ORM1, PIN1, SAA1, SFN, SLC2A4, SRF, TERT, YWHAZ ...
View as HTML - Web Search - eurogentec.be

Oncogenic Ki-Ras Inhibits the Expression of Interferon-responsive Genes through Inhibition of STAT 1 … - Full text - MIT Libraries
L Klampfer, J Huang, G Corner, J Mariadason, D … - J Biol Chem, 2003 - jbc.org
... cells is sufficient to inhibit the endogenous expression of STAT1 and STAT2, confirming
the ... factors, such as ELK-1, serum response factor (SRF), members of the ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

THERMODYNAMIC AND PARTICLE-DYNAMIC STUDIES ON SYNTHESIS OF SILICA NANOPARTICLES USING MICROWAVE- …
R Hong, J Ding, G Zheng - jproeng.com
Page 1. CHINA PARTICUOLOGY Vol. 2, No. 5, 207-214, 2004 THERMODYNAMIC AND
PARTICLE-DYNAMIC STUDIES ON SYNTHESIS OF SILICA NANOPARTICLES USING ...
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Inhibition of Stat1-mediated gene activation by PIAS1 - Full text - MIT Libraries
B Liu, J Liao, X Rao, SA Kushner, CD Chung, DD … - Cell, 1998 - dx.doi.org
... showed that PIAS1 was associated with Stat1 but not Stat2 or Stat3 after ... 1, a Potent
Transcriptional Coactivator for Serum Response Factor (SRF), Is Required ...
Cited by 182 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Crystal Structure of PU. 1/IRF-4/DNA Ternary Complex - Full text - MIT Libraries
CR Escalante, AL Brass, JMR Pongubala, E Shatova, … - Mol. Cell, 2002 - atlas.physbio.mssm.edu
... between SAP-1 and SRF also depends on a region out- side the Ets domain: aB box
that becomes ordered ... The mutant STAT1 and STAT2, contains residues (Asp104 and ...
Cited by 4 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Signaling from the IL-2 receptor to the nucleus
JX Lin, WJ Leonard - Cytokine Growth Factor Rev, 1997 - hivmedicine.md
... Stat5 Elf-1 SRF Elf-1 ... Stat2 [IFN/fl]), IL-2 rapidly activated STAT proteins, although
in this case, Stat3, Stat5a and Stat5b are the STAT proteins activated in ...
Cited by 53 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Modulation of Smooth Muscle Gene Expression by Association of Histone Acetyltransferases and … - Full text - MIT Libraries
D Cao, Z Wang, CL Zhang, J Oh, W Xing, S Li, JA … - Mol Cell Biol, 2005 - mcb.asm.org
... perhaps it selectively activates smooth muscle target genes by bridging SRF bound
at ... zinc finger domain CH1, which interacts with TBP, RXR, STAT2, and others ...
Cited by 3 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Ca 2-dependent regulation in neuronal gene expression - Full text - MIT Libraries
H Bito, K Deisseroth, RW Tsien - Curr Opin Neurobiol, 1997 - stanford.edu
... aspartate pCREB phospho-CREB PKA protein kinase A PP1 protein phosphatase 1 SAPK
stress-activated protein kinase SRE serum response element SRF serum response ...
Cited by 112 - View as HTML - Web Search - ncbi.nlm.nih.gov

Role of the tyrosine kinase JAK 2 in signal transduction by growth hormone - Full text - MIT Libraries
C Carter-Su, L Rui, J Herrington - Pediatric Nephrology, 2000 - springerlink.com
... 3 and 5. It did not stimulate the tyrosyl phos- phorylation of Stat2 (data not ... Stats
1 and 3, and a serum response element (SRE), which binds SRF and ternary ...
Cited by 8 - Web Search - cmmg.biosci.wayne.edu - ncbi.nlm.nih.gov

The carboxyl terminus of v-Abl protein can augment SH2 domain function - Full text - MIT Libraries
D Warren, AJ Heilpern, K Berg, N Rosenberg - J. Virol, 2000 - jvi.asm.org
... The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the ... Rho family
GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. ...
Cited by 5 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Diversity and Relatedness Among the Type I Interferons
J Chen, E Baig, EN Fish - Journal of Interferon & Cytokine Research, 2004 - dx.doi.org
... stimulated gene factor 3 (ISGF3), which is composed of transcriptional factors,
Stat1 and Stat2, and IFN ... IRP/CDP/CP1/CP2/H1 TF2/NF-1/NF-E/SRF AP-2 TGGGGA A1 a9 ...
Cited by 2 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Angiotensin peptides and inducible transcription factors - Full text - MIT Libraries
A Blume, T Herdegen, T Unger - Journal of Molecular Medicine, 1999 - springerlink.com
... proteins: STAT, CREB, ternary complex factors (TCF), serum response factor (SRF),
ATF-2 ... Stat1 and Stat2 (Stat 84) are rapidly tyrosine phosphorylated as well [85 ...
Cited by 25 - Web Search - ncbi.nlm.nih.gov

Mechanism of plasminogen activator inhibitor-1 regulation by oncostatin M and interleukin-1 in human … - Full text - MIT Libraries
A Kasza, DL Kiss, S Gopalan, W Xu, RE Rydel, A Koj … - Journal of Neurochemistry, 2002 - blackwell-synergy.com
... but can activate c-fos expression via serum response factor (SRF) (Montaner et ... Urokinase
induces activation and formation of Stat4 and Stat1-Stat2 complexes in ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Nuclear calcium: a key regulator of gene expression
GE Hardingham, H Bading - Biometals, 1998 - springerlink.com
... The SRE comprises a core element 5'-CC[A/T] 6 GG-3' that is the binding site for
serum response factor, SRF (Treisman 1987; Schroter et al. 1987; Norman et al. ...
Cited by 21 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

A Stat1 a Factor Regulates the Expression of the Human Vimentin Gene by IFN-g
ES IZMAILOVA, SR SNYDER, ZE ZEHNER - JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2000 - dx.doi.org
... Other Stat family members, for example, Stat2, Stat4, and Stat6, have been
shown to be induced by other cytokines, such as IFN- a
Cited by 4 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth … - Full text - MIT Libraries
DW Leaman, S Pisharody, TW Flickinger, MA Commane, … - Mol Cell Biol, 1996 - mcb.asm.org
... Role of STAT2 in the alpha interferon signaling pathway. ... The SRF accessory protein
Elk-1 contains a growth factor-regulated transcriptional activation domain. ...
Cited by 105 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Transcriptional control of gene expression
W Johnson, JL Jameson - Principles of Molecular Medicine. Humana Press Inc., Towota, …, 1998 - humanapress.com
... SRE) recruits ternary complex factors (Ets-1). The syn- ergistic interaction between
SRF and Ets ... JunB, YY1, E1a, SV40 Tag, c-Myb, SRC-1, Sap 1a, STAT2, MyoD, E2F ...
Cited by 3 - View as HTML - Web Search - modares.ac.ir

Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors - Full text - MIT Libraries
S Pelletier, F Duhamel, P Coulombe, MR Popoff, S … - Mol Cell Biol, 2003 - mcb.asm.org
... The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the ... Rho family
GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. ...
Cited by 17 - Web Search - pubmedcentral.nih.gov - dx.doi.org - all 7 versions »

Signal Transduction Pathways Induced by GM-CSF in Microglia: - Full text - MIT Libraries
SM LIVA, MA KAHN, JM DOPP, J DE VELLIS - GLIA, 1999 - doi.wiley.com
... Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene
expression in ... Contribution of both STAT and SRF/TCF to c-fos promoter activation ...
Cited by 1 - Web Search - doi.wiley.com

Regulation of intercellular adhesion molecule-1 (CD54) gene expression
KA Roebuck, A Finnegan - J Leukoc Biol, 1999 - jleukbio.org
... The SRE (serum response element) is bound by serum response factor (SRF)
that recruits Elk-1 to form a ternary complex [139]. Elk ...
Cited by 85 - Web Search - jleukbio.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Recent advances in angiotensin II signaling - Full text - MIT Libraries
RM Touyz, C Berry - Braz J Med Biol Res, 2002 - scielo.br
... of the STAT proteins p91/84 (STAT1a/ß), p113 (STAT2) and p92 ... of the myosin
light-chain phosphatase; PRK2, protein kinase C-related kinase; SRF, serum response ...
Cited by 30 - Cached - Web Search - scielo.br - ncbi.nlm.nih.gov

[CITATION] Signal Transduction Virtual Journal - Full text - MIT Libraries
S Pelletier, F Duhamel, P Coulombe, MR Popoff, S … - Mol. Cell. Biol
Web Search

STAT 4 Is Required for Interleukin-12-induced Chromatin Remodeling of the CD 25 Locus - Full text - MIT Libraries
A O'Sullivan, HC Chang, Q Yu, MH Kaplan - J Biol Chem, 2004 - jbc.org
... what has been seen for STAT1 and STAT2 promoter binding. ... STAT1 binding to the Class
II transactivator promoter and STAT2 to the ISG54 promoter ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

The mechanism of IL-5 signal transduction - Full text - MIT Libraries
T Adachi, R Alam - Am J Physiol Cell Physiol, 1998 - ajpcell.physiology.org
... members of the STAT family have been identified: STAT1 (STAT1 , STAT1 ), STAT2,
STAT3, STAT4 ... The SRF accessory protein Elk-1 contains a growth factor-regulated ...
Cited by 48 - Web Search - ajpcell.physiology.org - ncbi.nlm.nih.gov

Departments of Biochemistry and Molecular Biophysics, and Medicine Washinaton Universitv School of …
AM Gronowski, Z Zhong, Z Wen, MJ Thomas, JE … - mend.endojournals.org
... Both proteins are related to previously characterized Stat1 and Stat2, and there
is approximately 40-50% identity between any pair of these four sequences (14 ...
Web Search

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
Page 1. Molecular Vision 2004; 10:163-76 <http://www.molvis.org/molvis/v10/a22>
Received 3 October 2003 | Accepted 16 March 2004 | Published 22 March 2004 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

Assembly requirements of PU. 1–Pip(IRF-4) activator complexes: inhibiting function in vivo using … - Full text - MIT Libraries
AL Brass, AQ Zhu, H Singh - The EMBO Journal, 1999 - embojournal.npgjournals.com
... SAP-1, to the c-fos promoter by the serum response factor, SRF (Dalton and ... with
IRF-2 (Sharf et al., 1997 ) or p48's association with STAT1 and STAT2 (Veals et ...
Cited by 52 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Bovine interferon-tau stimulates the Janus kinase-signal transducer and activator of transcription … - Full text - MIT Libraries
M Binelli, P Subramaniam, T Diaz, GA Johnson, TR … - Biol Reprod, 2001 - biolreprod.org
... Application of genomic DNA affinity chromatography identifies multiple
interferon-alpha-regulated Stat2 complexes. J Biol Chem 1996; 271:12408–12413. ...
Cited by 14 - Web Search - biolreprod.org - bioone.org - ncbi.nlm.nih.gov - all 7 versions »

CELLULAR SIGNALLING PATHWAYS: NEW TARGETS IN LEUKAEMIA THERAPY - Full text - MIT Libraries
F Ravandi, M Talpaz, H Kantarjian, Z Estrov - British Journal of Haematology, 2002 - blackwell-synergy.com
Full Article. View/Print PDF article (715K). Download to reference manager.
British Journal of Haematology Volume 116 Issue 1 Page ...
Cited by 9 - Web Search - ncbi.nlm.nih.gov

Gene Expression Profiling Reveals Role for EGF-Family Ligands in Mesangial Cell Proliferation
R Title - ajprenal.physiology.org
Page 1. Gene Expression Profiling Reveals Role for EGF-Family Ligands in Mesangial
Cell Proliferation Running Title: Expression Profiling in Mesangial Cells ...
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CELLULAR SIGNALLING PATHWAYS: NEW TARGETS IN LEUKAEMIA THERAPY - Full text - MIT Libraries
CMJAKS SIGNALLING - British Journal of Haematology, 2002 - ingentaconnect.com
... Thrombopoietin Jak2 Stat5a, Stat5b Jak2 Stat5a, Stat5b Interferons: IFNa, IFNb Jak1,
Tyk2 Stat1, Stat2 IFNc Jak1, Jak2 Stat1 IL-10à Jak1, Tyk2 Stat3 ...
Web Search

Modulation of Cellular Signaling Pathways - Full text - MIT Libraries
F Ravandi, M Talpaz, Z Estrov - Clinical Cancer Research, 2003 - clincancerres.aacrjournals.org
... For example, ATRA up-regulates Stat1 and Stat2 activity in the IFN- signaling pathway,
thereby potentiating the growth-inhibitory effects of IFN- (211, 212, 213 ...
Cited by 7 - Web Search - pharmacology.case.edu - pharm.cwru.edu - ncbi.nlm.nih.gov - all 7 versions »

Recent advances in angiotensin II signaling - Full text - MIT Libraries
C Berry - Braz J Med Biol Res, 2002 - scielo.br
... AT 1 receptor-induced activation of JAK leads to phosphorylation of the STAT proteins
p91/84 (STAT1a/ß), p113 (STAT2) and p92 (STAT3), which are transcription ...
View as HTML - Web Search - scielo.br

Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression … - Full text - MIT Libraries
Y Gu, MC Byrne, NC Paranavitana, B Aronow, JE … - Mol Cell Biol, 2002 - mcb.asm.org
Page 1. M OLECULAR AND C ELLULAR B IOLOGY , Nov. 2002, p. 7645–7657 Vol.
22, No. 21 0270-7306/02/$04.00 0 DOI: 10.1128/MCB.22.21 ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - stanford.edu - ncbi.nlm.nih.gov - all 6 versions »

[BOOK] Protein kinase functions
JR Woodgett - 2000 - print.google.com
... Page 9. 3.2 JAK2 200 3.3 JAK3 203 3.4 Tyk2 206 3.5 Stati 206 3.6 Stat2 208 3.7 Stat3
209 3.8 Stat4 21 1 3.9 Stat6 212 3.10 Stat4/Stat6 (—/—) 214 3.1 1 Stat5 ...
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