Activated G Protein-coupled Receptor Induces Tyrosine Phosphorylation of STAT3 and Agonist-selective … - Full text - MIT Libraries
REONC PROLIFERATION - J Biol Chem, 1999 - jbc.org
... of ERK1, ERK2, STAT3, and Elk1-- To analyze changes in the phosphorylation status
of ERK1 and ERK2 and the transcription factors STAT3 and Elk1 at various ...
Cited by 19 - Web Search - jbc.org - ncbi.nlm.nih.gov

Global Gene Expression Analysis of Keloid Fibroblasts in Response to Electron Beam Irradiation … - Full text - MIT Libraries
M Tosa, M Ghazizadeh, H Shimizu, T Hirai, H … - Journal of Investigative Dermatology, 2005 - blackwell-synergy.com
... 6, was downregulated, we sought to examine changes in mRNA expression of two downstream
targets in the IL-6 signaling pathway, namely STAT3 and ELK1 and found ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

GEArray Q Series Mouse Neurotrophin and Receptors Gene Array: AR-SAMM-018
FG Grouping, S Molecules, E Atf, AR Genes, B Apaf - eurogentec.be
... Signaling Molecules: Atf2, Elk1, Ets1, Fos, Jun, Mef2c, Myc, Ncoa1,
Rps6ka6-Rik, Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, Stat6 ...
View as HTML - Web Search - eurogentec.com

Independent and Cooperative Activation of Chromosomal c-fos Promoter by STAT 3 - Full text - MIT Libraries
E Yang, L Lerner, D Besser, JE Darnell Jr - J Biol Chem, 2003 - ncbi.nlm.nih.gov
... Also, when resident nuclear proteins such as ELK1 are activated to varying extents
by mitogen-activated protein kinase pathways, STAT3 activation provides a 2 ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

Oligo GEArray® Human Neurotrophin and Receptors Microarray
S Conditions - search.cosmobio.co.jp
... NR1I2. Transcription factors: ELK1, ETS1, JUN, MEF2C, MYC, NR1I2, STAT1, STAT2,
STAT3, STAT4, STAT5A, STAT5B, TP53. Storage Conditions ...
View as HTML - Web Search

Alcohol-Induced c-Fos Expression in the Edinger-Westphal Nucleus: Pharmacological and Signal … - Full text - MIT Libraries
RK Bachtell, NO Tsivkovskaia, AE Ryabinin - Alcohol, 2002 - jpet.aspetjournals.org
... serine 727 phospho-signal transducer and activator of transcription 3 (Stat3) but
no changes in phospho-cAMP response element-binding protein and phospho-Elk1. ...
Cited by 8 - Web Search - intl-jpet.aspetjournals.org - ncbi.nlm.nih.gov

PESI - An intelligent system for Prediction of Enzyme - Substrate Interactions based on experimental … - Full text - MIT Libraries
G Nudelman, T Tennenbaum, R Mehr, R Unger - In Silico Biology, 2002 - bioinfo.de
... ERK1, mbp, +, –. ERK2, map2, +, –. ERK2, mbp, +, –. ERK2, Elk1, +, –. akt1, GSK3, +, –.
ilk1, akt1, +, –. ... The program predicted the protein STAT3 as a substrate ...
Cached - Web Search - bioinfo.de - ncbi.nlm.nih.gov

Growth Hormone Receptor Signalling and Actions in Bone Growth
PA Kelly, J Finidori, S Moulin, C Kedzia, N Binart … - Hormone Research, 2001 - content.karger.com
... tyrosine is required for this effect, it appears that Stat1 and Stat3 activation
is ... MAP kinase substrates include the ternary complex factor or Elk1, Egr1, and ...
Cited by 3 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

PESI oe An Intelligent System for Prediction of Enzyme-Substrate Interactions Based on Experimental … - Full text - MIT Libraries
G Nudelman, T Tennenbaum, R Mehr, R Unger - In Silico Biology, 2002 - iospress.metapress.com
... ERK1 mbp + œ ERK2 map2 + œ ERK2 mbp + œ ERK2 Elk1 + œ akt1 GSK3 + œ ilk1 akt1 +
œ ... The program predicted the protein STAT3 as a substrate candidate. ...
Web Search

Des-{gamma}-carboxy Prothrombin Is a Potential Autologous Growth Factor for Hepatocellular Carcinoma - Full text - MIT Libraries
M Suzuki, H Shiraha, T Fujikawa, N Takaoka, N Ueda … - J Biol Chem, 2005 - jbc.org
... Gene Reporter Assay—The reporter plasmids, 30 µg of pFA2-Elk1, 30 µg of ... For the STAT3
activity reporter assay, 30 µg of pSTAT3-Luc (Clontech laboratories ...
Web Search - jbc.org - ncbi.nlm.nih.gov

The hepatitis C virus NS5A protein inhibits activating protein-1 (AP1) function by perturbing Ras- … - Full text - MIT Libraries
A Macdonald, K Crowder, A Street, C McCormick, K … - J Biol Chem, 2003 - jbc.org
... phosphorylated ETS-family transcription factor Elk1 (39). ... activity, ERK has a number
of independent functions including regulation of the STAT3 ...
Cited by 2 - Web Search

TNF-{alpha} Induces Tyrosine Phosphorylation and Recruitment of the Src Homology Protein-Tyrosine … - Full text - MIT Libraries
JG Bode, J Schweigart, J Kehrmann, C Ehlting, F … - The Journal of Immunology, 2003 - jimmunol.org
... chimeric receptor (EG(YYYYYY), the pFR-Luc plasmid and the pFA2 Elk1 plasmid of ... in
inhibition of IL-6 signaling by TNF- , the inhibition of STAT3 and promoter ...
Cited by 1 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov

Glucose-dependent insulinotropic polypeptide is a growth factor for ß (INS-1) cells by pleiotropic … - Full text - MIT Libraries
A Trumper, K Trumper, H Trusheim, R Arnold, B Goke … - Mol Endocrinol, 2001 - mend.endojournals.org
... 701 of STAT1, serine 727 of STAT3, tyrosine 705 of STAT3, tyrosine 694 ... Transreporting
System for Elk1 and CREB Phosphorylation INS-1 cells were grown for 48 h ...
Cited by 40 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

Activation of c-fos by lipopolysaccharide in glial cells via p 38 mitogen-activated protein kinase- … - Full text - MIT Libraries
A Simi, Y Edling, M Ingelman-Sundberg, N Tindberg - Journal of Neurochemistry, 2005 - blackwell-synergy.com
... However, it was recently described that STAT3 can influence c-fos transcription
in ... by directly interacting with other DNA-bound proteins such as Elk1 (Yang et ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B ...
Factors: ATF2, CEBPB, CREB1, CREBBP, EGFR, EGR1, EGR2, EGR3, ELK1, ELK3, ELK4 ...
View as HTML - Web Search - eurogentec.be

GEArray Q Series Human EGF/PDGF Signaling Pathway Gene Array: AR-SAHS-040
FG Grouping, R Ligands, N Regulators, IS Molecules - eurogentec.be
... CREB1, CSNK2A1 (CK-II alpha), CSNK2B (CK-II beta), DUSP6, EIF4E, ELK1, GRB2, HRAS ...
ACTR3, ARHA (RhoA), JAK1, PLCG1, PLCG2, PRKCA (PKC alpha), STAT1, STAT3, STAT5A ...
View as HTML - Web Search - eurogentec.com

GEArray Q Series Human Neurotrophin and Receptors Gene Array: AR-SAHS-018
FG Grouping - eurogentec.com
... Signaling Molecules: ATF2, ELK1, ETS1, FOS, JUN, MEF2C, MYC, NCOA1, NELL1,
RPS6KA6, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B Apoptosis ...
View as HTML - Web Search - eurogentec.be

Growth Hormone Receptor Signalling and Actions in Bone Growth
PAKJF Stephanie, MC Kedzia, N Binart - Horm Res, 2001 - content.karger.com
... tyrosine is required for this effect, it appears that Stat1 and Stat3 activation
is ... MAP kinase substrates include the ternary complex factor or Elk1, Egr1, and ...
Web Search - content.karger.com

UVA Induces Ser 381 Phosphorylation of p 90 RSK/MAPKAP-K 1 via ERK and JNK Pathways - Full text - MIT Libraries
Y Zhang, S Zhong, Z Dong, N Chen, AM Bode, W Ma, Z … - J Biol Chem, 2001 - jbc.org
... STAT3 was used as an internal control to determine equal loading of protein. ... JNK2,
or p38 kinase was tested by incubating with kinase substrates, Elk1, or ATF2 ...
Cited by 26 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The Hepatitis C Virus Non-structural NS 5 A Protein Inhibits Activating Protein-1 Function by … - Full text - MIT Libraries
A Macdonald, K Crowder, A Street, C McCormick, K … - J Biol Chem, 2003 - jbc.org
... is bound by the phosphorylated ETS family transcription factor Elk1 (39 ... a number
of independent functions including regulation of the STAT3 transcription factor ...
Cited by 5 - Web Search - jbc.org - virologyj.com - ncbi.nlm.nih.gov - all 5 versions »

Ataxia Telangiectasia Mutated Proteins, MAPKs, and RSK 2 Are Involved in the Phosphorylation of STAT … - Full text - MIT Libraries
Y Zhang, YY Cho, BL Petersen, AM Bode, F Zhu, Z … - J Biol Chem, 2003 - jbc.org
... kinase were incubated for 20 min at 30 °C, respectively, with Elk1, c-Jun ... or p38
kinase and their corresponding controls, as well as STAT3-mediated luciferase ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The role of apoptosis in response to photodynamic therapy: what, where, why, and how - Full text - MIT Libraries
NL Oleinick, RL Morris, I Belichenko, NL Oleinick, … - Photochem. Photobiol. Sci, 2002 - pubs.rsc.org
Page 1. The role of apoptosis in response to photodynamic therapy: what, where,
why, and how Nancy L. Oleinick,* Rachel L. Morris and Irina Belichenko ...
Cited by 70 - Web Search - dx.doi.org - members.rsc.org - ncbi.nlm.nih.gov - all 8 versions »

CrkII Participation in the Cellular Effects of Growth Hormone and Insulin-like Growth Factor-1 - Full text - MIT Libraries
ELK Goh, T Zhu, S Yakar, D LeRoith, PE Lobie - J. Biol. Chem, 2000 - jbc.org
... determined as described under "Experimental Procedures." The position of the
phospho-Elk1 fusion protein ... A, effect of hGH and hIGF-1 on STAT1 and STAT3 (c-fos ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

CIS 3/SOCS-3 Suppresses Erythropoietin(EPO) Signaling by Binding the EPO Receptor and JAK 2 - Full text - MIT Libraries
A Sasaki, H Yasukawa, T Shouda, T Kitamura, I … - J Biol Chem, 2000 - jbc.org
... Luciferase Assay-- The STAT3 and STAT5 responsive promoter-luciferase reporter gene,
which ... 293 cells were transfected with 0.05 µg of pFA-Elk1, 0.1 µg of pFR ...
Cited by 73 - Web Search - jbc.org - ncbi.nlm.nih.gov

RhoA/ROCK Activation by Growth Hormone Abrogates p 300/Histone Deacetylase 6 Repression of Stat 5- …
L Ling, PE Lobie - Journal of Biological Chemistry - jbc.org
... tyrosine and serine residues of Stat3 and subsequent activation of Stat3 essential
for ... 1 phosphorylation was detected by use of a specific phospho-Elk1 (Ser-383 ...
Cited by 2 - Web Search - jbc.org - Get it from MIT Libraries

The Androgen Receptor Gene is Preferentially Hypermethylated in Follicular Non-Hodgkin’s Lymphomas - Full text - MIT Libraries
H Yang, CM Chen, P Yan, TH Huang, H Shi, M Burger, … - Clin Cancer Res, 2003 - 140.120.130.112
... NM_005229 ELK1 Xp11.2 ELK1, member of ETS oncogene family NM_000125 ESR1 6q25 Estrogen
receptor 1 ... AR (Ps) ELK1 (Ps) Locus 1 2.19 10 4 Locus 1 7.93 10 3 ...
Cited by 3 - View as HTML - Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive … - Full text - MIT Libraries
VN Ivanov, TK Hei - Oncogene, 2005 - nature.com
... Two fundamental signaling path- ways, Ras-Raf-MEK-ERK-(Elk1, activator protein ... of
tyrosine phosphoryla- tion and functional activation of Stat3, which controls ...
Cited by 1 - Web Search - nature.com - ncbi.nlm.nih.gov

A Maximum Entropy Approach to Biomedical Named Entity Recognition
YF Lin, TH Tsai, WC Chou, KP Wu, TY Sung, WL Hsu - iasl.iis.sinica.edu.tw
... An NE may belong to multiple categories, eg, ELK1 is both a DNA and ... PKC, calcineurin,
molecules, GM-CSF, GATA-1, IL- 12, subunit, cell, STAT3, family, antibody ...
Cited by 1 - View as HTML - Web Search - iis.sinica.edu.tw - cs.rpi.edu - iis.sinica.edu.tw - all 5 versions »

Gab 2 Is Phosphorylated on Tyrosine upon Interleukin-2/Interleukin-15 Stimulation in Mycosis- …
JL Brockdorff, H Gu, T Mustelin, K Kaltoft, C … - Experimental and Clinical Immunogenetics, 2001 - content.karger.com
... involved in T cell trans- formation, and constitutively activated Stat3 has been ...
SHP2 inhibited cytokine-induced Stat5 as well as Elk1-mediated transactivation ...
Cited by 4 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Prolactin and growth hormone signal transduction in lymphohaemopoietic cells - Full text - MIT Libraries
L Yu-Lee, G Luo, S Moutoussamy, J Finidori - Cellular and Molecular Life Sciences(CMLS), 1998 - springerlink.com
... PRL acti- vates Stat1, Stat3 and Stat5 in Nb2 cells [46 ... toskeletal proteins or
transcription factors like c-jun and ternary complex factor or elk1 (see review ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov

c-Cbl Is a Negative Regulator of GH-Stimulated STAT5-Mediated Transcription - Full text - MIT Libraries
EL Goh, T Zhu, WY Leong, PE Lobie - Endocrinology, 2002 - endo.endojournals.org
... A, Western blot analysis with anti-phospho-Elk1 to demonstrate the activity of p44 ...
and STAT6 turnover but not that of STAT1, STAT2, and STAT3 by significantly ...
Cited by 4 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

Keyword index
Z Cu - aging - ingentaconnect.com
... 1256 electrospray ionization–quadrupole time of flight, 1306 Elk1, 915 endocannabinoid ...
apparatus, 597 sprouting, 831 Src, 1377 Stat1, 505 Stat3, 505 statins ...
Web Search - blackwell-synergy.com - Get it from MIT Libraries

T-cell-derived Interleukin-17 Regulates the Level and Stability of Cyclooxygenase-2 (COX-2) mRNA … - Full text - MIT Libraries
WH Faour, A Mancini, QW He, JA Di Battista - J. Biol. Chem, 2003 - jbc.org
... phospho-p44/42 (Thr 202 /Tyr 204 ), and total and anti-phospho-STAT3 (Ser 727 ). ...
and c-Jun, whereas rhIL-1 activated the transactivational capacity of Elk1 (Fig ...
Cited by 7 - Web Search - jbc.org - ncbi.nlm.nih.gov

Mcl-1 is a common target of stem cell factor and interleukin-5 for apoptosis prevention activity via … - Full text - MIT Libraries
HM Huang, CJ Huang, JJ Yen - Blood, 2000 - bloodjournal.org
... 1 cells stimulated by IL-5 (lane 3). Among other STAT family members, STAT3 was
slightly ... P-Elk1 is the product of the kinase reaction of MAP kinase and H2B is ...
Cited by 37 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... 2). In some cases, as few as four motifs were used (eg, ELK1 01, HNF4 02 B, DTYPEPA
B), while in others as many as 389 motifs were used (TATA 01) (Fig. ...
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TRANSGENIC MODELS OF GROWTH HORMONE ACTION - Full text - MIT Libraries
JJ Kopchick, LL Bellush, KT Coschigano - Annual Review of Nutrition, 1999 - nutr.annualreviews.org
... STAT1, STAT3, STAT5, and possibly STAT4 are found in GH-induced DNA binding complexes
of several genes (Figure 1). For example, STAT1, STAT3, and in ... TCF /ELK1, ...
Cited by 29 - Web Search - nutr.annualreviews.org - ncbi.nlm.nih.gov

Activation of JNK by TPA promotes apoptosis via PKC pathway in gastric cancer cells - Full text - MIT Libraries
Y Chen, Q Wu, SY Song, WJ Su - World J Gastroenterol, 2002 - wjgnet.com
... and activation of the transcription factors, such as c-Jun, ATF2, and ElK1 [12,13 ...
Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun ...
Cited by 10 - View as HTML - Web Search - wjgnet.com - wjgnet.com - ncbi.nlm.nih.gov - all 5 versions »

Funktion der Protein-Tyrosin-Phosphatase SHP2 und des feedback-Inhibitors SOCS3 in der IL-6- …
RWTH Aachen, U Lehmann, PDJ Mey - sylvester.bth.rwth-aachen.de
... Page 15. Einleitung 6 Nach IL-6 Stimulation werden STAT1 und STAT3 über ihre
SH2-Domänen an die Membran- ... Dabei bindet STAT3 an die Erkennungssequenz ...
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[CITATION] Signal Transduction Virtual Journal - Full text - MIT Libraries
V Cavalli, P Kujala, J Klumperman, LSB Goldstein - J. Cell Biol
Web Search

[CITATION] Sunday Driver links axonal transport to damage signaling - Full text - MIT Libraries
V Cavalli, P Kujala, J Klumperman, LSB Goldstein - The Journal of Cell Biology, 2005
Page 1. THE JOURNAL OF CELL BIOLOGY © The Rockefeller University Press $8.00
The Journal of Cell Biology, Vol. 168, No. 5, February ...
Web Search - jcb.org - jcb.org - ncbi.nlm.nih.gov

MAP kinases - Full text - MIT Libraries
Z Chen, TB Gibson, F Robinson, L Silvestro, G … - Chem. Rev, 2001 - audreyli.com
Page 1. MAP Kinases Zhu Chen, † Tara Beers Gibson, Fred Robinson, Loraine
Silvestro, Gray Pearson, Bing-e Xu, Angelique Wright, Colleen ...
Cited by 70 - View as HTML - Web Search - ncbi.nlm.nih.gov

BY THE TELJAK2 ONCOPROTEIN
JMY Ho - collectionscanada.ca
Page 1. THE ACTIVATION OF MITOGEN-ACTIVATED PROTEIN KINASE PATHWAYS BY THE
TELJAK2 ONCOPROTEIN Jenny Mei-Yen Ho A thesis submitted ...
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Epidermal Growth Factor and Thrombin Induced Proliferation of ImmortalizedHuman Keratinocytes is … - Full text - MIT Libraries
K Kaufmann andGeraldThiel - Journal of Cellular Biochemistry, 2002 - doi.wiley.com
... mous epithelial cells EGF stimulation induces the phosphorylation of STAT3 [Grandis
et al ... The ternary complex factor Elk1 is phosphorylated by ERK, connect- ing ...
Web Search

The IMPACT™ of Protein Splicing Research
MQ Xu - neb.com
Page 1. January 1997 Vol. 8 No. 2 Inside : printed on recycled paper A Scientific
Newsletter from New England Biolabs (continued on page 2) ...
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Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
... Transcription Hs.321677 STAT3 Signal transducer and activator of
transcription 3 (acute-phase response factor) 17q21 437.5 VH W ...
Cited by 3 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Identification of the Critical Features of a Small Peptide Inhibitor of JNK Activity - Full text - MIT Libraries
RK Barr, TS Kendrick, MA Bogoyevitch - J Biol Chem, 2002 - jbc.org
... example is seen with the single replacement within a STAT3-binding phosphopeptide ...
I-JIP Also Prevents JNK Phosphorylation of ATF2 and Elk1-- JNKs phosphorylate ...
Cited by 30 - Web Search - jbc.org - ncbi.nlm.nih.gov

病毒性肝炎发病机制中的反式调节机制
成军 - wjgnet.com
... 可显著激活ＭＡＰＫ／ＥＲＫ的级联反应包括Ｅｌｋ１． ＨＣＶ
核 ... ＬＩＦ）诱导ＳＴＡＴ３ 的信号转导． 但对于 ...
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Hepatocyte transformation and tumor development induced by hepatitis C virus NS3 c-terminal deleted … - Full text - MIT Libraries
QQ He, RX Cheng, Y Sun, DY Feng, ZC Chen, H Zheng - World J Gastroenterol, 2003 - wjgnet.com
... Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c ... core protein
enhances the acti- vation of the transcription factor, Elk1, in response ...
Cited by 7 - View as HTML - Web Search - wjgnet.com - wjgnet.com - ncbi.nlm.nih.gov - all 5 versions »

Signal transduction pathways: targets for green and black tea polyphenols - Full text - MIT Libraries
AM Bode, Z Dong - J. Biochem. Mol. Biol, 2003 - jbmb.or.kr
... theaflavin-3,3’-digallate decreased phosphorylation of ERK1/2, MEK1/2 and Elk1. ... of
transcription3 (STAT3) and ERKs was also inhibited by EGCG (Masuda et al ...
Cited by 10 - View as HTML - Web Search - ncbi.nlm.nih.gov - jbmb.or.kr - jbmb.or.kr

The Formin/Diaphanous-related Protein, FHOS, Interacts with Rac 1 and Activates Transcription from … - Full text - MIT Libraries
JJ Westendorf - J Biol Chem, 2001 - jbc.org
... factor, SRF (25), and certain Ets domain proteins, such as Elk1 and SAP1, that ... other
Rac1-inducible pathways including the E2F (43), pRb (43), and STAT3 (44, 45 ...
Cited by 21 - Web Search - jbc.org - ncbi.nlm.nih.gov