Expression of Bcl-2 and Bcl-xL in Cutaneous and Bone Marrow Lesions of Mastocytosis - Full text - MIT Libraries
K Hartmann, M Artuc, SE Baldus, TK Zirbes, B … - Am J Pathol, 2003 - ajp.amjpathol.org
... 45 It can therefore be speculated that certain transcription factors such as STAT3
and GATA1 may be involved in modulating the expression of bcl-2 and bcl-xL ...
Cited by 3 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self- … - Full text - MIT Libraries
QL Ying, J Nichols, I Chambers, A Smith - Cell, 2003 - genetics.wisc.edu
... Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration
with STAT3 ... activating the transcription factor STAT3. ...
Cited by 62 - View as HTML - Web Search - ucsf.edu - mouse.snu.ac.kr - 147.46.21.237 - all 7 versions »

Short Communication
K Hartmann, M Artuc, SE Baldus, TK Zirbes, B … - American Journal of Pathology, 2003 - ajp.amjpathol.org
Page 1. Short Communication Expression of Bcl-2 and Bcl-xL in Cutaneous and
Bone Marrow Lesions of Mastocytosis Karin Hartmann,* Metin ...
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GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive … - Full text - MIT Libraries
K Onodera, S Takahashi, S Nishimura, J Ohta, H … - Proc. Natl. Acad. Sci. USA, 1997 - dx.doi.org
... Y. Miura, K. Ozawa, and N. Komatsu A functional role of Stat3 in in ... Lei, PE Bennett,
BM Weinstein, and PP Liu A nonsense mutation in zebrafish gata1 causes the ...
Cited by 57 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Oligo GEArray® Human Hematopoietic Stem Cells and Hematopoiesis Microarray
S Conditions - search.cosmobio.co.jp
... BCL11A, CBFB, CD80, CD86, CEBPE, CEBPG, EGR1, ETS1, ETV6, GATA1, GATA2, GFI1 ... NOTCH1,
NOTCH2, NOTCH4, PAX5, RBPSUH, RHOH, RUNX1, SCAND1, STAT1, STAT3, STAT4, TAL1 ...
View as HTML - Web Search

Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice - Full text - MIT Libraries
M Yanagida, M Osato, N Yamashita, H Liqun, B Jacob … - Oncogene, 2005 - nature.com
... of RUNX1, which could stimulate cyclin D expression through its interaction with
STAT3. This growth advantage, when partnered with a GATA1 mutation that blocks ...
Web Search - nature.com - ncbi.nlm.nih.gov

Too Much Interference: Injection of Double-Stranded RNA Has Nonspecific Effects in the Zebrafish … - Full text - MIT Libraries
A Oates, AE Bruce, RK Ho - Developmental Biology, 2000 - ingentaconnect.com
... mRNAs from the papc, tbx6, and gata1 genes, which depend on tbx16/spt function ... of
genes that are unaffected by the spt mutation, such as catenin, stat3, and no ...
Cited by 33 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Hematopoietic gene expression profile in zebrafish kidney marrow
HD Song, XJ Sun, M Deng, GW Zhang, Y Zhou, XY Wu, … - Proceedings of the National Academy of Sciences - pnas.org
... a number of genes encoding homologues of human cytokines, jak1, stat3, raf, erk1 ...
transcription factors associated with globin switch such as GATA1, YY1, NR2F2 ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - snhs-plin.barry.edu - dx.doi.org - all 6 versions » - Get it from MIT Libraries

Molecular Mechanisms of Megakaryocyte Differentiation - Full text - MIT Libraries
H Schulze, RA Shivdasani - Seminars in Thrombosis and Hemostasis, 2004 - thieme-connect.com
... 981-986 12 Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A. GATA1 mutations in ...
4045-4052 68 Kirito K, Osawa M, Morita H. A functional role of Stat3 in in ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Targets of the transcriptional repressor oncoprotein Gfi-1 - Full text - MIT Libraries
Z Duan, M Horwitz - Proceedings of the National Academy of Sciences, 2003 - pnas.org
... IL-2, Jak3, IL-6 receptor, and Stat3 represent ligand-activated ... GATA1 transcription
factor is indispensable for erythroid and megakaryocyte development (29, 30 ...
Cited by 9 - Web Search - pnas.org - dx.doi.org - ncbi.nlm.nih.gov

Zebrafish: An emerging genetic model for the study of cytokines and hematopoiesis in the era of …
GJ Lieschke - Int. J. Hematol, 2001 - cardenjennings.metapress.com
... 22,23]; gata2 U18312 and reference 24, NP_032116; gata1 U18311, S04655 ... jak2a AJ005690,
NM_008413 [30]; stat1 AJ005692, NM_009283 [31]; stat3 AJ005693, U30709 ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression … - Full text - MIT Libraries
AC Oates, A Brownlie, SJ Pratt, DV Irvine, EC Liao … - Blood, 1999 - bloodjournal.org
... the nomenclature for alternately spliced forms of the mammalian STAT1 and STAT3
genes ... 65 Cells in this region have earlier expressed scl 66 and gata1 and gata2 ...
Cited by 27 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Targets of the transcriptional repressor oncoprotein Gfi-1 - Full text - MIT Libraries
S Tables, Z Duan, M Horwitz - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... IL-2, Jak3, IL-6 receptor, and Stat3 represent ligand-activated ... GATA1 transcription
factor is indispensable for erythroid and megakaryocyte development (29, 30 ...
Web Search

The‘definitive’(and‘primitive’) guide to zebrafish hematopoiesis - Full text - MIT Libraries
AJ Davidson, LI Zon - Oncogene, 2004 - nature.com
... (in press) spt/tbx16 T-box spadetail Thompson et al. (1998) stat3 STAT — Oates et
al. (1999) ... (1995) gata1 Zinc-finger vlad tepes Detrich et al. (1995) ...
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Novel transcription factors in human CD34 antigen-positive hematopoietic cells - Full text - MIT Libraries
I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, … - Blood, 2002 - bloodjournal.org
... GATA1 and GATA2 are down-regulated ... Transcription Hs.321677 STAT3 Signal transducer
and activator of transcription 3 (acute-phase response factor) 17q21 437.5 VH ...
Cited by 3 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 7 versions »

Erythropoietin receptor and STAT5-specific pathways promote SKT6 cell hemoglobinization - Full text - MIT Libraries
RC Gregory, N Jiang, K Todokoro, J Crouse, RE … - Blood, 1998 - bloodjournal.org
... of select lineage-restricted trans-factors, including GATA1, 1 Friend of GATA1
(FOG), 2 ... binding domains of murine STAT5A (Thr 409 -Arg 523 ) and STAT3 (Asn 400 ...
Cited by 20 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... Table 2 TFBS with known “terminal N” artifacts in TRANSFAC ® TFBS family Description
GATA1 02 GATA-binding factor 1 GATA1 03 GATA-binding factor 1 GATA1 ...
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Cloning and Characterization of Ehox, a Novel Homeobox Gene Essential for Embryonic Stem Cell … - Full text - MIT Libraries
M Jackson, JW Baird, N Cambray, JD Ansell, LM … - J Biol Chem, 2002 - jbc.org
... The antisense-expressing cells showed no increase in Gata1 expression over ... signaling
cytokines have clearly implicated the transcription factor STAT3 in the ...
Cited by 9 - Web Search - jbc.org - dx.doi.org - ncbi.nlm.nih.gov

Report on the ‘Expert Workshop on the Biology of Chromosome 21: towards gene-phenotype … - Full text - MIT Libraries
K Gardiner, MT Davisson, M Pritchard, D Patterson, … - Cytogenetic and Genome Research, 2005 - content.karger.com
... Principal classes include transcription fac- tors (FOXO1A, STAT3, CREB1 and GLI)
and ... Sheba Medical School, Tel Aviv) described acquired mutations in GATA1, an X ...
Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

Identification of YB-1 as a regulator of PTP 1 B expression: implications for regulation of insulin … - Full text - MIT Libraries
T Fukada, NK Tonks - The EMBO Journal, 2003 - embojournal.npgjournals.com
... GATA family-binding proteins (Fukada and Tonks, 2001), antibodies to GATA1 and GATA2 ...
downstream of the receptor, in that the phosphorylation of STAT3 (Figure 7C ...
Cited by 10 - Web Search - emboj.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion.
SM Onnebo, MM Condron, DO McPhee, GJ Lieschke, AC … - Experimental Hematology, 2005 - eanimal.snu.ac.kr
... tel-jak2a (D,F,H), were analyzed for expression of gata1 at 24 hpf ... Tyrosine-dependent
and independent mechanisms of STAT3 activation by the human granulo- cyte ...
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Enforced Activation of STAT 5 A Facilitates the Generation of Embryonic Stem-Derived Hematopoietic … - Full text - MIT Libraries
JJ Schuringa, K Wu, G Morrone, MAS Moore - Stem Cells, 2004 - stemcells.alphamedpress.org
... day 7. Lysates were Western blotted using antibodies against STAT5, STAT3, OCT4,
and ... on day 7. Similarly, the definitive hematopoiesis marker GATA1 was first ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

Thrombopoietin: a pan-hematopoietic cytokine
AE Geddis, HM Linden, K Kaushansky - Cytokine Growth Factor Rev, 2002 - cardio.bjmu.edu.cn
... domains. For example, STAT3 and STAT5 are recruited to phospho- tyrosines
Tyr 112 and Tyr 117 and phosphorylated by JAK2 [96]. The ...
Cited by 9 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor … - Full text - MIT Libraries
K Li, MP Menon, VG Karur, S Hegde, DM Wojchowski - Blood, 2003 - bloodjournal.org
... Stat1) and interferon (IFN) response pathways 17,18 and for a PY704 Stat3 (and/or ...
containing and PY-null EpoR forms in transgenic mice from a Gata1 gene vector ...
Cited by 3 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov - all 7 versions »

Differentiation status dependent function of FOG-1 - Full text - MIT Libraries
M Tanaka, J Zheng, K Kitajima, K Kita, H Yoshikawa … - Genes to Cells, 2004 - blackwell-synergy.com
... (2001) Platelet characteristics in patients with X-linked macrothrombocytopenia
because of a novel GATA1 mutation. Blood 98, 85 92. ...
Web Search - ingentaconnect.com - genestocellsonline.org - ncbi.nlm.nih.gov

Gene Targeting and Transgenic Strategies for the Analysis of Hematopoietic Development in the Mouse
HKA Mikkola, SH Orkin - Methods Mol Med, 2005 - neurosci.humanapress.com
... Cre Mouse Strategy Deletion Notes References GATA1 Transgene General or red cells,
megakaryocytes, mast cells Early embryonic excision more 44,45 ...
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A mouse model for visualization and conditional mutations in the erythroid lineage - Full text - MIT Libraries
AC Heinrich, R Pelanda, U Klingmuller - Blood, 2004 - bloodjournal.org
... STAT3 is constitutively active in some patients with Polycythemia rubra vera ... Jasinski
M, Keller P, Fujiwara Y, Orkin SH, Bessler M. GATA1-Cre mediates Piga gene ...
Cited by 5 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid … - Full text - MIT Libraries
JJ Schuringa, KY Chung, G Morrone, MAS Moore - J Exp Med, 2004 - jem.org
... GATA1 was expressed in CB CD34 + cells, but was not significantly up ... Constitutive
activation of STAT3 and STAT5 is induced by leukemic fusion proteins with ...
Cited by 4 - Web Search - jem.org - jcb.org - ncbi.nlm.nih.gov

Molecular control of megakaryopoiesis and thrombopoiesis
I Matsumura, Y Kanakura - Int. J. Hematol, 2002 - cardenjennings.metapress.com
... JAKs), thereby activating intracel- lular signaling cascades, such as signal
transducers and acti- vators of transcription (STATs, STAT1, STAT3, and STAT5 ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Technical Bulletin
H Protein, H ELISA - sigmaaldrich.com
... Cy3/Cy5-biotin BSA CAMK4 GATA1 APSCR1 HPFM2_TechBul .indd 12 HPFM2_TechBull.indd
12 ... Array not drawn to scale. Cy3/Cy5-biotin BSA CAMK4 GATA1 APSCR1 ...
View as HTML - Web Search - sigmaaldrich.com

Erythropoietin-induced activation of STAT5 is impaired in the myelodysplastic syndrome - Full text - MIT Libraries
LH Hoefsloot, MP van Amelsvoort, L Broeders, DC … - Blood, 1997 - bloodjournal.org
... it has been established that inhibition of STAT5 and GATA1 interferes with ... human
granulocyte colony-stimulating factor receptor is required for STAT3 but not ...
Cited by 25 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 6 versions »

Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein {beta … - Full text - MIT Libraries
YW Liu, HP Tseng, LC Chen, BK Chen, WC Chang - J. Immunol, 2003 - jimmunol.org
... studies of LPS-induced gene expression of human IL-10, transcription factors STAT3
and SV40 ... Yin and Yang 1 (43), the p65 subunit of NF- B (44), GATA1 (45), and ...
Cited by 6 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov

Regulatory Factors Involved in Cardiogenesis
B Zheng, JK Wen, M Han - BIOCHEMISTRY (Moscow), 2003 - springerlink.com
... GATA proteins have been divided into two subfami lies, GATA1, 2, and ... Jak tyrosine
kinases results in tyrosine phosphorylation of the STAT3 transcription factor ...
Cited by 1 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - maik.ru - all 5 versions » - Get it from MIT Libraries

Structural organization and classification of the human mucin genes
N Moniaux, F Escande, N Porchet, JP Aubert, SK … - Front Biosci, 2001 - xylian.igh.cnrs.fr
... bind AP1, AP2, AP3, AP4, CTF/NF1, ER, PR, Sp1, STAT1, STAT3, STAT5, and ... WAP), elements
specific for transcription in hemapoetic cells (BKLF/TEFII, GATA1, v-Myb ...
Cited by 57 - Cached - Web Search - bioscience.org - bioscience.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

The possible role and application of WT1 in human leukemia
Z Chen - Int J Hematol, 2001 - cardenjennings.metapress.com
... The mediators in the signal transduction pathway of G-CSF/G-CSFR (receptor), Stat3
and Stat3 , were constitutively activated in transfected cells, but ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genome-wide prediction and analysis of function-specific transcription factor binding sites - Full text - MIT Libraries
F Long, H Liu, C Hahn, P Sumazin, MQ Zhang, A … - In Silico Biology, 2004 - iospress.metapress.com
... IL-10 gene via a module consisting of interdependent IRF1 and STAT3 motifs [Ziegler ...
GATA1 06(M00347) 9.56E-04 The GATA transcription factor family has been ...
Cited by 1 - Web Search - bioinfo.de - bioinfo.de - ncbi.nlm.nih.gov

Stretch-inducible expression of the angiogenic factor CCN1 in vascular smooth muscle cells is …
UB KG, IF CG, HD DH - jbc.org
Page 1. Stretch induces CCN1 expression via Egr-1 1 Stretch-inducible
expression of the angiogenic factor CCN1 in vascular smooth ...
Web Search

DYRK3 Activation, Engagement of PKA/CREB and Modulation of Progenitor Cell Survival
K Li, S Zhao, V Karur, DM Wojchowski, D Wojchowski - jbc.org
... phosphorylating forkhead transcription factor FKHR (15), CREB (16) and STAT3 (17).
However, factors ... response to ectopically expressed Gata1) (30). ...
Web Search - jbc.org

The transcriptional co-activator P/CAF potentiates TGF-ß/Smad signaling - Full text - MIT Libraries
S Itoh, J Ericsson, J Nishikawa, CH Heldin, P ten … - Nucleic Acids Res, 2000 - nar.oupjournals.org
... For example, Stat3 and Smad1 are brought together within one functionally synergizing ...
has been reported for p300 following acetylation of p53 and GATA1 (25,26 ...
Cited by 25 - Web Search - nar.oupjournals.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Supplementary Data ‘Stemness’: Transcriptional Profiling of Embryonic and Adult Stem Cells
M Ramalho-Santos, S Yoon, Y Matsuzaki, RC Mulligan … - intl.sciencemag.org
... There are at least 7 additional homebox containing genes, including Pitx2. Other
nucleic acid binding factors of note are Gata1, 2 and 3, ...
Web Search

Cross Talk between Retinoic Acid Signaling and Transcription Factor GATA-2 - Full text - MIT Libraries
S Tsuzuki, K Kitajima, T Nakano, A Glasow, A … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... The forward and reverse primers used to detect human sequences were as follows:
GATA1, 5′-TGCTCTGGTGTCCTCCACAC and 5′-TGGGAGAGGAATAGGCTGCT; β2 ...
Cited by 1 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

IL-12-dependent nuclear factor-kappaB activation leads to de novo synthesis and release of IL-8 and …
F Al-Mohanna, S Saleh, RS Parhar, K Collison - J Leukoc Biol, 2002 - jleukbio.org
... of the signal transducer and activator of transcription family, AP1, GATA1 and
-2 ... L., de Groot, RP (1999) Lineage-specific activation of STAT3 by interferon ...
Cited by 8 - Web Search - jleukbio.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Predicting the effect of transcription therapy in hematologic malignancies
A Melnick - Leukemia, 2005 - nature.com
... 53 A recent report identified peptide aptamers that bind the STAT3 dimerization
domain, block its transcriptional activity and caused apoptosis when transduced ...
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Blood First Edition Paper, prepublished online November 2, 2004; DOI 10.1182/blood-2004-09-3459
P Isolation, GGE Analysis - uni-ulm.de
... Within the Gata family, Gata1 was expressed exclusively in EP, and Gata-2 ... within
the STAT family, Stat3 and Stat4 expression was stronger in GMP while Stat5a ...
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Rapid Generation of de novo Biological Pathways from Large-Scale Gene Expression Data Using the …
DC Siu - ingenuity.com
... STAT3, STAT5A, IRF1, Alpha tubulin, PLCG2, GAB2, DOK1, CBLB, MAP4K1, SHC1, BLNK ... PIN1,
PTPRC, GATA1, SPI1, CEBPB, CEBPE, QKI, MHC class II, SCD1, Calmodulin, NFIC ...
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Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit ( … - Full text - MIT Libraries
G Terszowski, C Waskow, P Conradt, D Lenze, J … - Blood, 2005 - bloodjournal.org
... Within the Gata family, Gata1 was expressed exclusively in EPs and Gata-2 ... Finally,
within the STAT family, Stat3 and Stat4 expressions were stronger in GMPs ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood … - Full text - MIT Libraries
K Kitajima, M Masuhara, T Era, T Enver, T Nakano - The EMBO Journal, 2002 - embojournal.npgjournals.com
... c-Myb was analyzed (Figure 7B). When a GATA-1 promoter (GATA1-luc) was ... Self-renewal
of pluripotent embryonic stem cells is mediated via activation of STAT3. ...
Cited by 20 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

Regulation of skeletal development by the Runx family of transcription factors - Full text - MIT Libraries
T Komori - Journal of Cellular Biochemistry, 2005 - doi.wiley.com
... 447 Page 4. mice by introducing Cbfb using the Gata1 promoter, which directs
transgene expression to erythroid and megakaryocytic lineages. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION - Full text - MIT Libraries
CT Kuo, JM Leiden - Annual Review of Immunology, 1999 - immunol.annualreviews.org
... The GATA family of vertebrate transcription factors contains six members,
GATA1-GATA6, each of which contains a highly related DNA-binding domain composed ...
Cited by 125 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

Cooperation of Spi-1/PU. 1 with an activated erythropoietin receptor inhibits apoptosis and Epo- … - Full text - MIT Libraries
CT Quang, O Wessely, M Pironin, H Beug, J Ghysdael - The EMBO Journal, 1997 - embojournal.npgjournals.com
... known to play a pivotal role in erythropoiesis, including GATA1, GATA2 and ... Friend
cells also results in the constitutive activation of STAT1, STAT3 and STAT5 ...
Cited by 26 - Web Search - nature.com - emboj.org - ncbi.nlm.nih.gov - all 6 versions »