Oligo GEArray® Mouse JAK/STAT Signaling Pathway Microarray
I Response, S Conditions - search.cosmobio.co.jp
... activity: Crebbp, Il31ra, Ncoa1 Transcriptional activator activity: Ifng, Stat3
Other transcription factors and regulators: C2ta, Cebpb, Gata3, Hmga1, Ifnar2 ...
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Oligo GEArray® Human JAK/STAT Signaling Pathway Microarray
I Response, S Conditions - search.cosmobio.co.jp
... Stat3: A2M, BCL2L1, CDKN1A, CRP, IRF1, MMP3, MYC, SOCS1, TNFRSF6. Stat4: FCER2,
FCGR1A, IFNG, IRF1, MYC. ... Stat6: FCER1A, GATA3, IGHG3, IL4, IL4R, MAF. ...
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Leukemia Inhibitory Factor Is Linked to Regulatory Transplantation Tolerance.
SM Metcalfe, TJ Watson, S Shurey, E Adams, CJ … - Transplantation, 2005 - transplantjournal.com
... factor that transactivates the gene encoding IL-4, whilst GATA3 itself is ... Santa Cruz
Biotechnology USA were used for STAT 1 (sc346), STAT3 (sc7197), STAT5a and ...
Web Search - transplantjournal.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

GEArray Q Series Human JAK/STAT Signaling Pathway Gene Array:
FG Grouping - eurogentec.be
... Stat3: A2M, BCL2L1 (BclxL), CDKN1A (p21), CRP, IRF1, JUNB, MMP3, MYC, SOCS1, TNFRSF6
(Fas). ... Stat6: FCER1A, GATA3, IGHG3, IL4, IL4R, MAF. Stat1/Stat1/p48: GBP1. ...
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GEArray Q Series Mouse JAK/STAT Signaling Pathway Gene Array: AR-SAMM-039
FG Grouping - eurogentec.com
... Stat3: Bcl2l (BclxL), Cdkn1a (p21), Crp, Irf1, Junb, Mmp3, Myc, Pzp (A1m), Saa3,
Socs1, Tnfrsf6 (Fas). ... Stat6: Fcer1a, Gata3, Il4, Il4ra, Maf. ...
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GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A ... ETS1,
ETS2, FKBP1B, FLJ14639 (NIP45), FOS, FOSL1, FOXO1A, FOXO3A, GATA3, GATA4, GRLF1 ...
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Transcription Factors: New Targets for Antiallergic Therapy
D Quarcoo, E Hamelmann, F Alert - Pathobiology, 2002 - content.karger.com
... L, Ray P, Ray A: A critical role for NF-kappa B in GATA3 expression and ... Q, Geisler
C, Nissen MH, Ropke C, Wasik MA, Odum N: Constitutive STAT3-activation in ...
Cited by 1 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Differential activation of signal transducer and activator of transcription(STAT) 3 and STAT 5 and … - Full text - MIT Libraries
P Anderson, A Sundstedt, L Li, EJ O’Neill, S Li, … - International Immunology, 2003 - intimm.oupjournals.org
... h 1- and T h 2-specific transcription factors such as T-bet and GATA3 promote T ... The
selective activation of STAT3 and STAT5 pathways in T h 1 cells could be an ...
Cited by 2 - Web Search - intimm.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

MAPPIT: a cytokine receptor-based two-hybrid method in mammalian cells 1 - Full text - MIT Libraries
J Tavernier, S Eyckerman, I Lemmens, J Van der … - Clinical & Experimental Allergy, 2002 - blackwell-synergy.com
... Finally, expression of the GATA3 transcription factor is required for commitment
of ... receptor and heteromeric IL-6 receptor both use JAK2 and STAT3 in their ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production - Full text - MIT Libraries
RY Yu, X Wang, FJ Pixley, JJ Yu, AL Dent, HE … - Blood, 2005 - bloodjournal.org
... differentiation at least partly through its ability to negatively regulate GATA3,
a well ... that the inhibitory effect of BCL-6 on IL-6/STAT3 signaling represents ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Notch Governing Mature T Cell Differentiation - Full text - MIT Libraries
S Tsukumo, K Yasutomo - The Journal of Immunology, 2004 - jimmunol.org
... A critical role for NF- B in GATA3 expression and TH2 differentiation in allergic ...
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling ...
Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

The Role of STATs in Inflammation and Inflammatory Diseases
S PATHWAY - Current Pharmaceutical Design, 2004 - ingentaconnect.com
... of the STAT protein family in particular STAT1, STAT2, STAT3, STAT4 and ... of the
lineage-defining transcription factors T-bet and GATA3, respectively, which are ...
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Transcription Factors: New Targets for Antiallergic Therapy
DQE Hamelmann - Pathobiology, 2002 - content.karger.com
... L, Ray P, Ray A: A critical role for NF-kappa B in GATA3 expression and ... Q, Geisler
C, Nissen MH, Ropke C, Wasik MA, Odum N: Constitutive STAT3- activation in ...
Web Search - content.karger.com

Interleukin-6 promotes the production of interleukin-4 and interleukin-5 by interleukin-2-dependent … - Full text - MIT Libraries
IH Heijink, E Vellenga, P Borger, DS Postma, JGR … - Immunology, 2002 - blackwell-synergy.com
... phospho-Stat3 (New England Biolabs, Hitchin, UK), pan-p38 and pan-Stat3 (Santa Cruz ...
GATA3: 5'-GAACATCATCTCGGG-3' sense and 3'-CACGTACTGAGTGACCTTTC-5' antisense ...
Cited by 3 - Web Search - ingentaconnect.com - dissertations.ub.rug.nl - ncbi.nlm.nih.gov - all 7 versions »

G-CSF: A key regulator of neutrophil production, but that’s not all!
AW ROBERTS - Growth Factors, 2005 - taylorandfrancis.metapress.com
... 2002), and limits signalling by inhibiting STAT3 directly and by targeting the
activated ... to G-CSF in vitro demonstrate altered expression of GATA3 mRNA and ...
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BMC Genomics - Full text - MIT Libraries
JJ Hutton, AG Jegga, S Kong, A Gupta, C Ebert, S … - BMC Genomics, 2004 - biomedcentral.com
... Examples include PU.1/Ets, Ikaros, E2A, EBF, PAX5, GATA3, NFAT, cMYB, and OCT-2 ... both
signal transducers and activators of transcription (Stat1, Stat3, and Stat4 ...
Cited by 1 - View as HTML - Web Search - dx.doi.org - pubmedcentral.nih.gov - bmc.ub.uni-potsdam.de - all 8 versions »

ORIGINAL ARTICLE Expression of human pim family genes is selectively up-regulated by cytokines … - Full text - MIT Libraries
TLT Aho, RJ Lund, EK Ylikoski, S Matikainen, R … - Immunology, 2005 - blackwell-synergy.com
... be induced by IL-4 and to promote Th2-cell expansion in synergy with GATA3. ... the GAS
element of the pim-1 promoter, while IFN- stimulates STAT1, STAT3 and STAT4 ...
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Interleukin-2 family cytokines: potential for therapeutic immmunoregulation
FJ Dumont - dx.doi.org
... This induces the association of SHC and Stat proteins (Stat3 and Stat5) with the ...
4 is regu- lated by the T H 2-specific transcription factor GATA3, whereas its ...
Web Search - ashley-pub.com - ashley-pub.com

Immune networks in animal models of inflammatory bowel disease
A Mizoguchi, E Mizoguchi, AK Bhan - Inflamm Bowel Dis, 2003 - ibdjournal.com
... intestine; LT, lymphotoxin; LysMcre/Stat, mice in which STAT3 expression is ... Th2
differentiation is initiated by GATA3- and cMaf-mediated chromatin remodeling ...
Cited by 5 - Web Search - ibdjournal.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Lymphoid enhancer-binding factor-1 binds and activates the recombination-activating gene-2 promoter … - Full text - MIT Libraries
ZX Jin, H Kishi, XC Wei, T Matsuda, S Saito, A … - J. Immunol, 2002 - jimmunol.org
... with distinct transcription factors: Pax-5 (18, 19) in B cells and GATA3 (18) or
c ... at 4°C for 3 h. As a control, oligonucleotides, containing STAT3 binding site ...
Cited by 7 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

Kinetics of Senescence-associated Changes of Gene Expression in an Epithelial, Temperature-sensitive … - Full text - MIT Libraries
O Larsson, C Scheele, Z Liang, J Moll, C Karlsson, … - Cancer Res, 2004 - intl-cancerres.aacrjournals.org
... Five of these (Pparg, Gata3, M-twist, Dlx2, and Pem) are transcription factors,
and ... Stat3 and Itga5 have been described to have growth-regulatory as well as ...
Cited by 3 - Web Search - cgb.ki.se - intl-cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its … - Full text - MIT Libraries
M Becker, A Sommer, JR Kraetzschmar, H Seidel, HD … - Mol Cancer Ther, 2005 - mct.aacrjournals.org
... estrogen-responsive and which are down-regulated in MaCa 3366/TAM are cyclin D1
(65), GATA3 (66), PDZK1 ... The promoter contains three STAT3 DNA-binding sites (81 ...
Web Search - mct.aacrjournals.org - ncbi.nlm.nih.gov

Subburaj Ilangumaran Robert Rottapel - Full text - MIT Libraries
S Ilangumaran - Immunological Reviews, 2003 - ingentaconnect.com
... The promoter region of the SOCS1 gene contains binding sites for STAT1, STAT3 and
STAT6 (9, 20), which explains the induc- tion of SOCS1 gene by many cytokines ...
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A Distal Region in the Interferon-{gamma} Gene Is a Site of Epigenetic Remodeling and … - Full text - MIT Libraries
JH Bream, DL Hodge, R Gonsky, R Spolski, WJ … - J Biol Chem, 2004 - jbc.org
... However, we did not find Stat3 interacting with the distal Stat5 region ... to an enhancer
element that binds the Th2-specfic transcription factor GATA3 as well as ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov

Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells - Full text - MIT Libraries
H Kishi, ZX Jin, XC Wei, T Nagata, T Matsuda, S … - Blood, 2002 - bloodjournal.org
... transcription factors: Pax-5 18 , 19 in B cells and GATA3 18 or c ... 31 As a control,
oligonucleotides containing the STAT3 binding site (5'-TCGACTCGTTCCCAGCAGCAC-3 ...
Cited by 9 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION - Full text - MIT Libraries
CT Kuo, JM Leiden - Annual Review of Immunology, 1999 - immunol.annualreviews.org
... These include the Ikaros, LKLF, and GATA3 zinc-finger proteins; the Ets, CREB/ATF,
and NF- B/Rel/NFAT transcription factors; the Stat proteins; and HMG box ...
Cited by 125 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

Suppression of Nuclear Factor-kappa B Activation Pathway by Spice-Derived Phytochemicals:
BB AGGARWAL, S SHISHODIA - atherosclerosis - agrawal.org
... A critical role for NF-kappa B in GATA3 expression and TH2 differentiation ... Nuclear
factor-{kappa}B and STAT3 are constitutively active in CD138+ cells derived ...
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Molecular regulation of cytokine gene expression during the immune response
JP Viola, A Rao - J Clin Immunol, 1999 - springerlink.com
... Homozygous disruption of the STAT3 gene resulted in an embryonic lethal phenotype
that attests to the pleiotropic role of cytokines in early development (37). ...
Cited by 13 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity - Full text - MIT Libraries
D Artis, A Villarino, M Silverman, W He, EM … - J Immunol, 2004 - jimmunol.org
... (34), demonstrating that IL-27 can directly inhibit transcription of GATA3, a critical ...
the recognition that IL-27 can activate STAT1 and STAT3 (10, 15, 36 ...
Cited by 10 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Suppression of the Nuclear Factor-{kappa} B Activation Pathway by Spice-Derived Phytochemicals: … - Full text - MIT Libraries
N Products, G Expression, M Genetics - Ann. NY Acad. Sci, 2004 - annalsnyas.org
... A critical role for NF- B in GATA3 expression and TH2 differentiation in ... Nuclear
factor- B and STAT3 are constitutively active in CD138+ cells derived from ...
Cited by 1 - Web Search - annalsnyas.org - ncbi.nlm.nih.gov

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
Page 1. BioSystems xxx (2005) xxx–xxx A statistical analysis of the TRANSFAC database
Gary B. Fogel a , Dana G. Weekes a , Gabor Varga b , Ernst R. Dow b , ...
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Melanie A. Sherman The role of STAT6 in mast cell IL-4 production - Full text - MIT Libraries
MA Sherman - Immunological Reviews, 2001 - ingentaconnect.com
... a conditionally active mu- tant STAT6 show upregulation of the c-maf and GATA3 pro-
teins (40 ... Proc Natl Acad Sci USA variant of transcription factor STAT3, is a ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov

The‘definitive’(and‘primitive’) guide to zebrafish hematopoiesis - Full text - MIT Libraries
AJ Davidson, LI Zon - Oncogene, 2004 - nature.com
... stat3 STAT — Oates et al. ... Between 3–4 dpf, these cells can be detected by examining
the expression of genes such as ikaros, gata3, lck, and recombination ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Interleukin-5, eosinophilic diseases and therapeutic intervention.
L Zabeau, P Gevaert, C Bachert, J Tavernier - Curr Drug Targets Inflamm Allergy, 2003 - ingentaconnect.com
... Thus far, three GATA3 binding sites have been identified in the IL-5 promoter. ... STAT5
homologues STAT5A and STAT5B [94- 96], but also STAT1 [85,97], STAT3 [85,97 ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation - Full text - MIT Libraries
S Diehl, CW Chow, L Weiss, A Palmetshofer, T … - J. Exp. Med, 2002 - intl.jem.org
... Tyk2 by IL-6 results in the phosphorylation and activation of STAT3 and, to ... by
IL-6 early during activation, but other transcription factors (eg, GATA3, c-maf ...
Cited by 18 - Web Search - dx.doi.org - jem.org - ncbi.nlm.nih.gov - all 5 versions »

Prediction of IFN g regulated gene transcription
H Liu, N Ge, KT Yu, D Krolikowski, A Zilberstein, … - bioinfo.de
... 2001]; the binding site of STATx (binding site for chimeric Stat1: Stat3 molecules)
[Horvath ... response, such as NF-AT and AP1 [Rao et al., 1997], GATA3 [Rao et ...
Cached - Web Search

Genome-wide prediction and analysis of function-specific transcription factor binding sites - Full text - MIT Libraries
F Long, H Liu, C Hahn, P Sumazin, MQ Zhang, A … - In Silico Biology, 2004 - iospress.metapress.com
... IL-10 gene via a module consisting of interdependent IRF1 and STAT3 motifs [Ziegler ...
GATA3 is involved in T helper cell differentiation and GATA4 is required for ...
Cited by 1 - Web Search - bioinfo.de - bioinfo.de - ncbi.nlm.nih.gov

Prediction of IFN γ Regulated Gene Transcription - Full text - MIT Libraries
H Liu, N Ge, KT Yu, D Krolikowski, A Zilberstein, … - In Silico Biology, 2004 - iospress.metapress.com
... 2001]; the binding site of STATx (binding site for chimeric Stat1: Stat3 molecules)
[Horvath ... response, such as NF-AT and AP1 [Rao et al., 1997], GATA3 [Rao et ...
Web Search - bioinfo.de - ncbi.nlm.nih.gov

Stretch-inducible expression of the angiogenic factor CCN1 in vascular smooth muscle cells is …
UB KG, IF CG, HD DH - jbc.org
Page 1. Stretch induces CCN1 expression via Egr-1 1 Stretch-inducible
expression of the angiogenic factor CCN1 in vascular smooth ...
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MOLECULAR MECHANISMS REGULATING TH1 IMMUNE RESPONSES - Full text - MIT Libraries
SJ Szabo, BM Sullivan, SL Peng, LH Glimcher - Annual Review of Immunology, 2003 - immunol.annualreviews.org
... IL-12R complex is coupled to the Jak-STAT signaling pathway, specifically to the
Jak2 and Tyk2 kinases and the transcription factors STAT1, STAT3, and STAT4 ...
Cited by 78 - Web Search - phyto.annualreviews.org - bio.classes.ucsc.edu - ncbi.nlm.nih.gov - all 8 versions »

Recreational music-making modulates the human stress response: a preliminary individualized gene … - Full text - MIT Libraries
BD Collection, CS Analysis, DD Interpretation, EM … - Med Sci Monit, 2005 - medscimonit.com
... phosphatedehydrogenase) GATA3 (GATA binding protein 3) ... 1) STAT3 (signal transducer
and activator of transcription 3 (acute-phase response factor)) ...
Cited by 1 - View as HTML - Web Search - medscimonit.com - ncbi.nlm.nih.gov

Cytokines and transcription factors that regulate T helper cell differentiation: new players and new …
D Agnello, CS Lankford, J Bream, A Morinobu, M … - J Clin Immunol, 2003 - springerlink.com
... Although Stat1, Stat3, Stat4, and Stat5 have all been reported to be activated by
IL-12, Stat4 appears to be the major player in IL-12-induced responses (61, 62 ...
Cited by 29 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

STRUCTURAL AND FUNCTIONAL SIMILARITIES AND DIFFERENCES BETWEEN THE GPS PROTEINS - Full text - MIT Libraries
H Jafar-Nejad, HJ Bellen - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... IL-6-mediated signaling through STAT3 is involved in the proliferation of T cells
upon antigenic stimulation, and the observation that Gfi-1 physically ...
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Oct-4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in … - Full text - MIT Libraries
DC Hay, L Sutherland, J Clark, T Burdon - Stem Cells, 2004 - intl-stemcells.alphamedpress.org
... Moreover, with the exception of Gata3, little induction was observed for either ...
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. ...
Cited by 12 - Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov - all 7 versions »

The origin of hematopoietic cell type diversity - Full text - MIT Libraries
T Hoang - Oncogene, 2004 - nature.com
... HEB, GATA3 ... self-renewal and differentiation in ES cells appears to depend on the
balance between the BMP-Smad (acting via Id) and the LIF-STAT3 path- ways ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
... protein 3 NM_003910 maternal G10 transcript G10 7q22.1 NM_003644 growth arrest-specific
7 GAS7 17p NM_002051 GATA binding protein 3 GATA3 10p15 NM_004492 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through … - Full text - MIT Libraries
S Ezoe, I Matsumura, S Nakata, K Gale, K Ishihara, … - Blood, 2002 - bloodjournal.org
... promoter is activated by Ras/Raf signaling and gp130-activated STAT3, 50 , 51 ... Targeted
disruption of the GATA3 gene causes severe abnormalities in the nervous ...
Cited by 7 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

[CITATION] NEW IL-12-FAMILY MEMBERS: IL-23 AND IL-27, CYTOKINES WITH DIVERGENT FUNCTIONS - Full text - MIT Libraries
CA Hunter - Nature Reviews Immunology, 2005
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THELPER D EVELOPMENT - Full text - MIT Libraries
KM Murphy, W Ouyang, JD Farrar, J Yang, S … - Annu. Rev. Immunol, 2000 - phyto.annualreviews.org
... Signaling through IL-12 receptor also activates Stat1 and Stat3 in addition to
Stat4, and yet neither Stat1 nor Stat3 induces Th1 development. ...
Cited by 1 - Web Search

Iron chelators inhibit VCAM-1 induction in dermal endothelial cells by acting as hypoxia mimetics
RA Swerlick, K Casper, S Caughman, B Boehme, A … - blackwell-synergy.com
... 004 IL-6-induced basic fibroblast growth factor 2 dependent angiogenesis in basal
cell carcinoma cells (BCC) via STAT3 and PI3-Kinase/Akt Pathway S Jee, 1,2 C ...
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