Transcription factor activities and gene expression during mouse mammary gland involution
A Marti, H Lazar, P Ritter, R Jaggi - J. Mammary Gland Biol. Neoplasia, 1999 - kluweronline.com
... events such as activation of protein kinase A and JNK 3 and changes in the activity
of several transcription factors including Stat5, Stat3, NF1, Oct-1, and AP ...
Cited by 19 - Web Search - springerlink.com - ingentaconnect.com - ubecx01.unibe.ch - all 5 versions »

GDNF-induced leukemia inhibitory factor can mediate differentiation via the MEK/ERK pathway in … - Full text - MIT Libraries
JI Park, JF Powers, AS Tischler, CJ Strock, DW … - Exp Cell Res, 2005 - ncbi.nlm.nih.gov
... the murine counterpart of the human gene mutated in neurofibromatosis type 1 (NF1). ...
LIF could activate MEK1/2 and STAT3, but LIF-induced differentiation was ...
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Oligo GEArray® Human Neurotrophin and Receptors Microarray
S Conditions - search.cosmobio.co.jp
... FGF2, GDNF, MEF2C, NELL1, NGFR, NRG1, NTF3, NTRK1, NTRK2, NTRK3, PTN, STAT3, TFG. ...
Cell cycle: BAX, BCL2, F2, FGF2, FGF9, IL1B, MYC, NF1, PTN, STAT1, TGFA, TGFB1 ...
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Developing a mammary gland is a stat affair
L Hennighausen, GW Robinson, KU Wagner, X Liu - J. Mammary Gland Biol. Neoplasia, 1997 - springerlink.com
... While Stat5 activity has been linked to alveolar proliferation and function, Stat3
activity correlates ... In addition to a nuclear factor 1 (NF1) and a NF«B site ...
Cited by 14 - Web Search - kluweronline.com - unmc.edu - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulatory elements of hepatitis B virus transcription - Full text - MIT Libraries
N Moolla, M Kew, P Arbuthnot - Journal of Viral Hepatitis, 2002 - blackwell-synergy.com
... 3) factor [39]. HNF-3, and possibly NF1, interact cooperatively with STAT3
and augment enhancer I function. IL6, which is required ...
Cited by 6 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Involvement of ras p21 Protein in Signal-Transduction Pathways from Interleukin 2, Interleukin 3, … - Full text - MIT Libraries
T Satoh, M Nakafuku, A Miyajima, Y Kaziro - Proceedings of the National Academy of Sciences - pnas.org
... and In Vivo Effects of a Farnesyltransferase Inhibitor on Nf1-Deficient Hematopoietic ...
T. Kanayasu-Toyoda, and T. Hayakawa The Role of STAT3 in Granulocyte ...
Cited by 100 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Oncostatin M Stimulates Transcription of the Human alpha 2 (I) Collagen Gene via the Sp 1/Sp 3- … - Full text - MIT Libraries
H Ihn, EC LeRoy, M Trojanowska - J Biol Chem, 1997 - jbc.org
... 4 was also competed off with an excess of NF1, Oct1, and SIE (a sis-inducible element
present in the c-fos promoter known to bind STAT1 and STAT3 (26, 27 ...
Cited by 84 - Web Search - jbc.org - ncbi.nlm.nih.gov

Different signaling pathways mediate regenerative versus developmental sensory axon growth - Full text - MIT Libraries
RY Liu, WD Snider - J. Neurosci, 2001 - jneurosci.org
... M, Nagata S, Hirano T, Fukui Y (1997) Dual control of neurite outgrowth by STAT3
and MAP ... 3 kinase are required for survival of wild-type and NF1 mutant sensory ...
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Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in …
J Chen, DL Clemens, AI Cederbaum, B Gao - Clin Biochem, 2001 - niaaa.nih.gov
... Chen J, Kunos G, Gao B. Ethanol rapidly inhibits IL-6-activated STAT3 and C ... regulation
of 1b adren- ergic receptors ( 1bAR) by nuclear factor 1 (NF1): a decline ...
Cited by 6 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

IDENTIFICATION OF MAMMARY GLAND INVOLUTION DIFFERENTIALLY EXPRESSED GENES IN BREAST CANCER TISSUES
T Erickson, BD Maciejko, C Gee, V Lam, D Ng, A … - tibetsjournal.org
... by changes in Ap-1, Nf1, Nfκb, Oct-1, p53, Stat3, and Stat5 transcription factor
levels with a concomitant upregulation of apoptosis-related genes such as ...
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Socs 3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced … - Full text - MIT Libraries
H Mori, R Hanada, T Hanada, D Aki, R Mashima, H … - Nature Medicine, 2004 - nature.com
... STAT3 signalling is required for leptin regulation of energy balance but not ... Ablation
of NF1 function in neurons induces abnormal development of cerebral ...
Cited by 15 - Web Search - nature.com - tufts.edu - ncbi.nlm.nih.gov

Studies of the regulation of the mouse carboxyl ester lipase gene in mammary gland - Full text - MIT Libraries
M Kannius-Janson, U Lidberg, K Hulten, A Gritli- … - Biochem. J, 1998 - biochemj.org
... The mutated sequence -1480/-1831 NF1:1 mut was then introduced into the ... Super-shifts
were performed by adding antibodies raised against STAT3, STAT5a, STAT5b ...
Cited by 13 - Cached - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Evolutionary aspects of the genomic organization of rat chromosome 10 - Full text - MIT Libraries
A Behboudi, E Sj&ouml strand, P G&oacute mez-Fabre … - Cytogenetic and Genome Research, 2002 - content.karger.com
... Cryba1 11(44.71) Cryba1 10 – 941 (D10Wox15) CRYBA1 17q11.2 28.5 30.2 30.2 Nf1
11(46.06) Nf1 10 – 957 (D10Got80) NF1 17q11.2 30.4 32.5 32.5 ...
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Zytokine, Zytokinrezeptoren und die haematopoetische Stammzelle
H Stammzellen, H Stammzellen - springerlink.com
... JAK) und die sog.„Signal Transducer and Ac- tivators of Transcription“ (STAT-Protei-
ne,STAT3 und STAT5),andererseits über die Ras-Nf1-MAPK- („mitogen ...
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肝炎病毒蛋白对肝细胞基因组转录调节及信号转导机制 的影响
成军, 成军 - wjgnet.com
... 但 是其他的转录因子如ＣＲＥＢ ＮＦ１ Ｃ／ＥＢＰ ... 体转染之后只有
４ｐＸ－１ 细胞中的Ｓｔａｔ３ 信号被激活说 明 ...
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Regulation of Gadd 45 gamma expression by C/EBP - Full text - MIT Libraries
N Jung, YW Yi, D Kim, M Shong, SS Hong, HS Lee, I … - European Journal of Biochemistry, 2000 - dx.doi.org
... tested by cotransfection of STAT3-C[26], the constitutively activated form of STAT3
(Fig ... Although an Oct 1 binding site, a CAAT box, and NF1 binding sites were ...
Cited by 8 - Web Search - content.febsjournal.org - ejbiochem.org - blackwell-synergy.com - all 7 versions »

Giant Cells: Contradiction to Two-Hit Model of Tuber Formation?
J Jozwiak, S Jozwiak - springerlink.com
... null NEP cells expressed high levels of phosphorylated S6K, S6, Stat3, and 4E ... to
tumorigenesis is exemplified by neurofibromatosis type 1 (NF1), where biallelic ...
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GEArray Q series Mouse cAMP/Ca2+ PathwayFinder Gene Array: AR-SAMM-028
FG Grouping - eurogentec.com
... Cables, Ccna1 (CyclinA), Ccnd1 (CyclinD1), Cdk5, Cdkn2b (p15IND4b), Gem, Nf1, Pcna,
Pmaip1 ... Jund1, Maf2-Ests, Nr4a2 (Nur77), Per1, Pit1, Pou2af1 (OCA- B), Stat3 ...
View as HTML - Web Search - eurogentec.be

GEArray Q series Human cAMP/Ca2+ PathwayFinder Gene Array: AR-SAHS-028
FG Grouping - eurogentec.com
... BRCA1, CCNA1 (CyclinA), CCND1 (CyclinD1), CDK5, CDKN2B (p15IND4b), GEM, NF1, PCNA,
PMAIP1 (NoxA ... MAF, NR4A2 (Nur77), PER1, POU1F1 (Pit-1), POU2AF1 (OCA-B), STAT3 ...
View as HTML - Web Search - eurogentec.be

SHP-2 and myeloid malignancies
M Tartaglia, CM Niemeyer, KM Shannon, ML Loh - Curr Opin Hematol, 2004 - co-hematology.com
... Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3-
and SHP2 ... 58.• Birnbaum RA, O'Marcaigh A, Wardak Z, et al.: Nf1 and Gmcsf ...
Cited by 8 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

IL-2 signalling in T and natural killer(NK) cells associated with their class I-non-restricted … - Full text - MIT Libraries
K YONEDA, T OSAKI, T YAMAMOTO - Clinical and Experimental Immunology, 1996 - ingentaconnect.com
... STAT2 and STAT3 were not phosphorylated. ... and STAT3 was performed to determine whether
p95, p105 and p110 were associated with these JAK-STAT proteins (Fig. ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Regulation of Gadd45g expression by C/EBP
N Jung, YW Yi, D Kim, M Shong, SS Hong, HS Lee, I … - ingentaconnect.com
... tested by cotransfection of STAT3-C [26], the constitutively activated form of STAT3
(Fig ... Although an Oct 1 binding site, a CAAT box, and NF1 binding sites were ...
Web Search

Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of … - Full text - MIT Libraries
CK Yung, VL Halperin, GF Tomaselli, RL Winslow - Genomics, 2004 - ccbm.jhu.edu
... (A) Scatter plot of the log 2 intensities of 2200 control probes on a test array
(replicate A of NF3) versus those on a reference array (replicate A of NF1). ...
Cited by 6 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

mammary tissue - Full text - MIT Libraries
X LIu, GW ROBINSON, F GOUILLEUX, B GRONER, L … - Proc. Natl. Acad. Sci. USA, 1995 - pnas.org
Page 1. Proc. Natl. Acad. Sci. USA Vol. 92, pp. 8831-8835, September 1995 Developmental
Biology Cloning and expression of Stat5 and an additional homologue ...
Cited by 1 - Web Search

Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities … - Full text - MIT Libraries
R Kurzrock, HM Kantarjian, JE Cortes, N Singhania, … - Blood, 2003 - bloodjournal.org
... Modulation of Akt, Erk, and signal transducer and activator of transcription 3
(STAT3) phosphorylation was variable, and responses occurred even without their ...
Cited by 18 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov - all 7 versions »

RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in …
E Puxeddu, JA Knauf, MA Sartor, N Mitsutake, EP … - Endocrine-Related Cancer, 2005 - journals.endocrinology.org
... Gstt1), signal transduction (Socs3, Nf1, Jak2, Cpg21, Dusp6, Socs1, Stat1, Stat3,
Cish) and transcription (Nr4a1, Junb, Hfh1, Runx1, Foxe1). ...
View as HTML - Web Search - erc.endocrinology-journals.org - journals.endocrinology.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Repressible transgenic model of NRAS oncogene–driven mast cell disease in the mouse - Full text - MIT Libraries
SM Wiesner, JM Jones, DE Hasz, DA Largaespada - Blood, 2005 - bloodjournal.org
... 36,37 NF1 patients are also at increased risk for the MPD/MDS syndrome ... Janus kinase
2–signal transducer and activator of transcription 3 (JAK2-STAT3) is one ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Structural organization and classification of the human mucin genes
N Moniaux, F Escande, N Porchet, JP Aubert, SK … - Front Biosci, 2001 - xylian.igh.cnrs.fr
... boxes. Other elements found are boxes that bind AP1, AP2, AP3, AP4,
CTF/NF1, ER, PR, Sp1, STAT1, STAT3, STAT5, and YY1. Different ...
Cited by 57 - Cached - Web Search - bioscience.org - bioscience.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Multiple prolactin (PRL) receptor cytoplasmic residues and Stat1 mediate PRL signaling to the … - Full text - MIT Libraries
Y Wang, KD O’Neal, L Yu-Lee - Mol Endocrinol, 1997 - mend.endojournals.org
... MG, Hackett RH, Larner AC, Farrar WL 1996 Prolactin recruits Stat1, Stat3, and Stat5 ...
Fed Eur Biochem Soc 350:177–182; Li S, Rosen JM 1995 CTF/NF1 and mammary ...
Cited by 10 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

CD 44-independent hepatocyte growth factor/c-Met autocrine loop promotes malignant peripheral nerve … - Full text - MIT Libraries
W Su, DH Gutmann, A Perry, R Abounader, J Laterra, … - Glia, 2004 - doi.wiley.com
... study of sporadic and NF1-associated tumors. Am J Clin Pathol 106:282–288. Hung
W, Elliott B. 2001. Co-operative effect of c-Src tyrosine kinase and Stat3 in ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

A common set of immediate-early response genes in liver regeneration and hyperplasia - Full text - MIT Libraries
J Locker, J Tian, R Carver, D Concas, C Cossu, GM … - Hepatology, 2003 - dx.doi.org
... PH ac- tivates nuclear factor B (NF- B) and Stat3, whereas TCPOBOP is a ligand for
the nuclear receptor, constitutive androstane receptor (CAR). ...
Cited by 5 - Web Search - doi.wiley.com - hepcvets.com - all 4 versions »

Genetics of pheochromocytoma and paraganglioma
DE Benn, DJBSA Marsh, BG Robinson - Current Opinion in Endocrinology & Diabetes, 2002 - co-endocrinology.com
... Pheochromocytomas occur in approximately 5% of patients with NF1, and patients have
a ... et al.: MEN2A-RET-induced cellular transformation by activation of STAT3. ...
Cited by 2 - Web Search - co-endocrinology.com

Inhibition of the interferon-gamma/signal transducers and activators of transcription (STAT) pathway … - Full text - MIT Libraries
B Chen, L He, VH Savell, JJ Jenkins, DM Parham - Cancer Res, 2000 - cancerres.aacrjournals.org
... anti-STAT1) added in Lane 15 and a STAT3 antibody (anti-STAT3) in Lane 16. ... at
cAMP-responsive element in the promoter regions of BRCA1 and NF1 inhibits binding ...
Cited by 37 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Dysmyelination and reduced myelin basic protein gene expression by oligodendrocytes of SHP-1- … - Full text - MIT Libraries
PT Massa, C Wu, K Fecenko-Tacka - Journal of Neuroscience Research, 2004 - doi.wiley.com
... An intriguing possibility is that STAT3 or other Erk-activated transcription factors
may act as ... of the myelin basic protein gene promoter requires the NF1 site ...
Web Search - ncbi.nlm.nih.gov

Oncogenic kinase signalling - Full text - MIT Libraries
P Blume-Jensen, T Hunter - Nature, 2001 - nature.com
References 1. Hunter, T. Signaling - 2000 and beyond. Cell 100, 113-127
(2000). | Article | PubMed | ISI | ChemPort |. 2. Pawson, T ...
Cited by 364 - Web Search - biochem.wisc.edu - bio.utexas.edu - lsic.ucla.edu - all 20 versions »

The Role of Cyclic-AMP Binding Protein(CREB) in Leukemia Cell Proliferation and Acute Leukemias
D SHANKAR, K SAKAMOTO - Leukemia & Lymphoma, 2004 - dx.doi.org
... (STAT3) activation, which regulates differentiation and survival, while SHP-2, Grb2 ...
Cognitive defects in neurofibro- matosis type 1 (NF1) mental retardation has ...
Cited by 1 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Affinity Purification of Sequence-Specific DNA Binding Proteins - Full text - MIT Libraries
JT Kadonaga, R Tjian - J. Virol, 2004 - pnas.org
... Home page, EMBO J. Home page Z. Wang, L. Bai, YJ Hsieh, and RG Roeder Nuclear factor
1 (NF1) affects accurate termination and multiple-round transcription by ...
Cited by 124 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Hypermethylation of the Inducible Nitric-oxide Synthase Gene Promoter Inhibits Its Transcription - Full text - MIT Libraries
Z Yu, BC Kone - J Biol Chem, 2004 - jbc.org
... EMSA, supershift analysis was performed with antibodies directed against STAT1,
STAT3, NF B ... element in the promoter regions of BRCA1 and NF1 inhibits binding ...
Cited by 1 - Web Search - jbc.org - ncbi.nlm.nih.gov

Transcriptional Regulation of the ß-Casein Gene by Cytokines: Cross-Talk between STAT5 and Other … - Full text - MIT Libraries
HW Dai Chida, A Yoshimura, A Miyajima - Molecular Endocrinology - mend.endojournals.org
... to be important for the optimal activation of STAT1 and STAT3 (3, 4 ... is regulated
by a cooperative interaction between two transcription factors, NF1 and STAT5 ...
Cited by 17 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

Transcription of the bone sialoprotein gene is stimulated by v-Src acting through an inverted CCAAT … - Full text - MIT Libraries
RH Kim, J Sodek - Cancer Res, 1999 - intl-cancerres.aacrjournals.org
... from Life Technologies, Inc., and the consensus oligonucleotides for CTF/NF1 and
CREB ... Among the members of this family, Stat3, which is activated by various ...
Cited by 21 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Conditional alleles in mice: Practical considerations for tissue-specific knockouts - Full text - MIT Libraries
KM Kwan - genesis, 2002 - doi.wiley.com
... c-Myc 15 (32.0) F de Alboran et al., 2001 Nf1 (neurofibromatosis type 1) 11
(46.1) ΠZhu et al., 2001 ... unknown F Wiebel et al., 2002* Stat3 ...
Cited by 27 - Web Search - tagc.univ-mrs.fr - biochem.wisc.edu - ncbi.nlm.nih.gov - all 6 versions »

Mitogenic signaling cascades in glial tumors
GS Kapoor, DM O'Rourke - Neurosurgery, 2003 - neurosurgery-online.com
... Coqueret O, Gascan H: Functional interaction of STAT3 transcription factor with
the cell ... KM, Loisel DA, Bronson RT, McLaughlin ME, Jacks T: Nf1;Trp53 mutant ...
Cited by 5 - Web Search - neurosurgery-online.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation - Full text - MIT Libraries
MC Harrisingh, E Perez-Nadales, DB Parkinson, DS … - The EMBO Journal, 2004 - nature.com
... 7600309; Published online 8 July 2004 Subject Categories: signal transduction;
differentiation & death Keywords: dedifferentiation; ERK; NF1; Ras; Schwann ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - embojournal.npgjournals.com - ncbi.nlm.nih.gov - all 5 versions »

Synergy of activin and ciliary neurotrophic factor signaling pathways in the induction of vasoactive … - Full text - MIT Libraries
AJ Symes, RL Pitts, J Conover, K Kos, J Coulombe - Mol Endocrinol, 2000 - mend.endojournals.org
... C) is composed of a Stat1 homodimer, and the middle complex (B) is a Stat3-Stat1
heterodimer ... These include AP-1, Sp1, NF1, and CarG elements (35, 36, 37, 38). ...
Cited by 6 - Web Search - mend.endojournals.org - ncbi.nlm.nih.gov

WL Blalock, C Weinstein-Oppenheimer, F Chang, PE Hoyle, XY Wang 3, PA Algate 4, RA Franklin, SM …
LS Steelman, JA McCubrey - Leukemia, 1999 - nature.com
... Interestingly, the neurofibromatosis-1 (NF1) gene, a tumor suppressor frequently
lost in juvenile chronic myelogenous leukemia (CML), is functionally related ...
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The 18 thAnnual Meeting of the Japanese Society for Pigment Cell Research November 27-28, 2004 … - Full text - MIT Libraries
G Eguchi, T Taga, DC Bennett, VC Gray-Schopfer, … - Pigment Cell Research, 2004 - blackwell-synergy.com
... This methylation was found to inhibit STAT3 binding to its recognition element ...
Neurofibromin, the NF1 gene product, is a major negative regulator of the Ras ...
Web Search - ncbi.nlm.nih.gov

The 18 thAnnual Meeting of the - Full text - MIT Libraries
J Kumamoto - Pigment Cell Res, 2004 - ingentaconnect.com
... In the neuroepithelial cells stimulated by LIF and BMP2, their respective downstream
transcription factors STAT3 and Smad1 form a complex in the nucleus with a ...
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A novel computational approach for the prediction of networked transcription factors of Ah-receptor … - Full text - MIT Libraries
A Kel, S Reymann, V Matys, P Nettesheim, E … - Molecular Pharmacology, 2004 - molpharm.aspetjournals.org
Page 1. MOL Manuscript # 1677R 1 A novel computational approach for the prediction
of networked transcription factors of Ah-receptor regulated genes . ...
Cited by 3 - Web Search - molpharm.org - molpharm.aspetjournals.org - ncbi.nlm.nih.gov - all 5 versions »

REGULATION OF MILK PROTEIN GENE EXPRESSION - Full text - MIT Libraries
JM Rosen, SL Wyszomierski, D Hadsell - Annual Review of Nutrition, 1999 - nutr.annualreviews.org
... STAT1 and STAT3 also are expressed during all stages of mammary gland development,
but they are phosphorylated in a pattern reciprocal to that of STAT5. ...
Cited by 42 - Web Search - bcm.edu - public.bcm.tmc.edu - ncbi.nlm.nih.gov - all 6 versions »

Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation - Full text - MIT Libraries
DR HODGE, B PENG, JC CHERRY, EM Hurt, SD Fox, JA … - Cancer Res, 2005 - cancerres.aacrjournals.org
... IL-6 induces expression of the Fli-1 proto-oncogene via STAT3. ... Oncogene
1996;12:1199–204.[Medline]; Furlong EE, Rein T, Martin F. YY1 and NF1 both activate ...
Cited by 1 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov