Rac1 mediates STAT3 activation by autocrine IL-6 - Full text - MIT Libraries
TR Faruqi, D Gomez, XR Bustelo, D Bar-Sagi, NC … - Cancer Res, 2005 - dx.doi.org
... Home page AK Kamaraju, C. Bertolotto, J. Chebath, and M. Revel Pax3 Down-regulation
and ... M. Krasilnikov, and Ze Ronai Regulation of Fas Expression by STAT3 and c ...
Cited by 25 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Pax 3 Down-regulation and Shut-off of Melanogenesis in Melanoma B 16/F 10. 9 by Interleukin-6 … - Full text - MIT Libraries
AK Kamaraju, C Bertolotto, J Chebath, M Revel - J Biol Chem, 2002 - jbc.org
... This suggests that Stat3 may affect Pax3 and cell shape by modulating signaling
networks rather than by activating STAT target genes. ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov

Interplay between MITF, PIAS3, and STAT3 in Mast Cells and Melanocytes - Full text - MIT Libraries
A Sonnenblick, C Levy, E Razin - Mol Cell Biol, 2004 - mcb.asm.org
... Pax3 down-regulation and shut-off of melanogenesis in melanoma B16/F10 ... Dominant negative
stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

The Transcription Network Regulating Melanocyte Development and Melanoma - Full text - MIT Libraries
KW Vance, CR Goding - Pigment Cell Research, 2004 - blackwell-synergy.com
... The results clearly linked IL6 signalling to the transcription factor STAT3, but
how STAT3 mediated the down-regulation of Pax3 expression was not clear. ...
Cited by 9 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Akt Modulates STAT 3-mediated Gene Expression through a FKHR(FOXO 1 a)-dependent Mechanism - Full text - MIT Libraries
M Kortylewski, F Feld, KD Krueger, G Bahrenberg, … - Journal of Biological Chemistry, 2003 - jbc.org
... turned out to be very potent in transcriptional activation, although PAX3-FKHR proteins ...
C terminus of FKHR is required for an efficient cooperation with STAT3. ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov

Sarcoma Meeting Stuttgart 2005
G Bacci, FG Barr, SJ Xia, M Bernstein, C Montreal, … - taylorandfrancis.metapress.com
... These cancers typically have a characteristic 2;13 chromosomal translocation, which
fuses the PAX3 and FKHR genes and results in a chimeric PAX3-FKHR protein. ...
Web Search

C/EBP-Induction by gp130 Signaling
AK Kamaraju, S Adjalley, P Zhang, J Chebath, M … - jbc.org
... The F10.9 cells respond to IL6RIL6 by a Stat3-mediated down- regulation of Pax3c,
a loss of Pax3-Sox10 synergism, leading to a reduction of transcription ...
Web Search

MyoD Induces Growth Arrest Independent of Differentiation in Normal and Transformed Cells - Full text - MIT Libraries
M Crescenzi, TP Fleming, AB Lassar, H Weintraub, … - Proceedings of the National Academy of Sciences - pnas.org
... and Y. Kanakura Reciprocal Inhibition between MyoD and STAT3 in the ... notch inhibits
muscle differentiation without affecting Myf5 and Pax3 expression in chick ...
Cited by 70 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu

Microarray Analysis of the Involution Switch
RWE Clarkson, CJ Watson - Journal of Mammary Gland Biology and Neoplasia, 2003 - kluweronline.com
... Our results show that both Stat3 and NF-kB target genes are induced by the involution
switch while Stat5 target genes are distinct from Stat3 induced genes. ...
Cited by 3 - Web Search - springerlink.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Inhibition of melanoma inhibitory activity(MIA) expression in melanoma cells leads to molecular and … - Full text - MIT Libraries
J Tatzel, I Poser, J Schroeder, AK Bosserhoff - Pigment Cell Research, 2005 - blackwell-synergy.com
... melanoma cell clones resulted in downregulation of Trp-1. To identify the molecular
mechanisms of MIA regulating pigmentation, MITF and PAX3, two positive ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Embryo morphogenesis: getting down to cells and molecules - Full text - MIT Libraries
L Solnica-Krezel, S Eaton - Development, 2003 - dx.doi.org
... discussed two systems that act downstream of the Pax3 transcription factor ... human
cancer cell lines support this notion; interfering with STAT3 function, using ...
Cited by 4 - Web Search - dev.biologists.org - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver … - Full text - MIT Libraries
H Ye, AX Holterman, KW Yoo, RR Franks, RH Costa - Mol Cell Biol, 1999 - mcb.asm.org
... 1995. Rapid activation of the Stat3 transcription complex in liver regeneration. ...
The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar ...
Cited by 35 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Abstracts of papers presented at the tenth Mammalian Genetics and De elopment Workshop ( …
S HUXTABLE, P SAKER, L HADDAD, A HATTERSLEY - journals.cambridge.org
... Pax3-driven expression from the MITF promoter, a target of Pax3, in cell ... Of these,
activation of the latent transcription factor Stat3 has been shown to be ...
Web Search

Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with … - Full text - MIT Libraries
MK Oh, DR Scoles, C Haipek, AD Strand, DH Gutmann, … - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... as p53 [Zhao et al., 2000], EGR1 [Svaren et al., 2000], E2F [Ma et al., 2002], and
Pax3 [Mayanil et ... Rac and STAT3/5 [Pelton et al., 1998; Scoles et al., 2002]. ...
Web Search - cedars-sinai.edu - ncbi.nlm.nih.gov

Developing a strategy to define the effects of insulin-like growth factor-1 on gene expression … - Full text - MIT Libraries
T Liu, H Lai, W Wu, S Chinn, PH Wang - Circ Res, 2001 - circres.ahajournals.org
... Bcl-2. IGF-1 also increased the expression of cyclin D and STAT3, two proteins ... detect
activation of a myogenic transcription program by the PAX3-FKHR fusion ...
Cited by 15 - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - ahavj.ahajournals.org

Molecular Medicine
T Liu, H Lai, W Wu, S Chinn, PH Wang - sci.sdsu.edu
... Cyclin D3 D16309 161%1 PCNA Y00047 182%1 194%1 Transcription factors ID1 D10862
153%1 STAT3 X91810 171%1 RNA synthesis/processing HNRNP-K D17711 184%1 ...
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A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... of activated T-cells NMYC 01 N-Myc OCT1 02 Octamer factor 1 OCT1 03 Octamer factor
1 OCT1 04 Octamer factor 1 OCT1 Q6 Octamer factor 1 P300 01 p300 PAX3 B Pax3 ...
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Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate … - Full text - MIT Libraries
H Tiedemann, M Asashima, H Grunz, W Knochel - Dev. Growth Differ, 2001 - blackwell-synergy.com
... to elucidate the molecular mechanism of ES cell propagation in a pluripotent state
have identified the importance of the transcription factor STAT3, which is ...
Cited by 13 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Conditional alleles in mice: Practical considerations for tissue-specific knockouts - Full text - MIT Libraries
KM Kwan - genesis, 2002 - doi.wiley.com
... Pax3 1 (44.0) F Koushik et al., 2002* Pax5 ... Stat3 11 (60.5) F Takeda et al., 1998;
Chapman et al., 1999; Sano et al., 1999; Takeda et al., 1999 ...
Cited by 27 - Web Search - tagc.univ-mrs.fr - biochem.wisc.edu - ncbi.nlm.nih.gov - all 6 versions »

A slug, a fox, a pair of sox: Transcriptional responses to neural crest inducing signals
E Heeg-Truesdell, C LaBonne - Birth Defects Research Part C Embryo Today Reviews, 2004 - doi.wiley.com
... Factors such as Pax3 and Msx-1 are expressed in two broad domains along the
anterior-posterior axis, which include placodal, neural crest, and dorsal neural ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Basic and clinical neuroscience applications of embryonic stem cells
S GOKHAN, MD MEHLER - THE ANATOMICAL RECORD (NEW ANAT.), 2001 - doi.wiley.com
... STAT3, an acute phase response factor activated by sev- eral different cytokine ... in
addition to transcriptional regulators of neural tube patterning (Pax3 and 6 ...
Cited by 11 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

TranSignal TM GR-TF Interaction Arrays
PU Manual - panomics.com
... ARE ARE EGR (1) EGR (1) HNF-4 HNF-4 NF-E2 NF-E2 PRE PRE Stat1 Stat1 USF-1 USF-1
6 Br n-3 Br n-3 ERE ERE IRF-1 IRF-1 NFkB NFkB RAR(DR5) RAR(DR5) Stat3 Stat3 VDR ...
View as HTML - Web Search - biocat.de

Cellular and molecular regulation of muscle regeneration - Full text - MIT Libraries
SB Charge, MA Rudnicki - Physiol Rev, 2004 - intl-physrev.physiology.org
... musculature. Pax3 promotes myogenesis in the lateral myotome. ... tube. B: Pax3 expression
in precursor cells contributes to myogenic cell expansion. ...
Cited by 37 - Web Search - intl-physrev.physiology.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Gene expression in human neural stem cells: effects of leukemia inhibitory factor - Full text - MIT Libraries
LS Wright, J Li, MA Caldwell, K Wallace, JA … - Journal of Neurochemistry, 2003 - blackwell-synergy.com
... signal transducer and activator of transcription 1 and 3 (STAT1, STAT3) were modulated
by ... 2002) but not PAX3, 4 or 8. Interestingly, a number of genes that we ...
Cited by 29 - Web Search - ingentaconnect.com - cnc.cj.uc.pt - med.usf.edu - all 9 versions »

Analysis of the Protein Kinase B–Forkhead box O signaling pathway
APJ van den Heuvel - igitur-archive.library.uu.nl
Page 1. Analysis of the Protein Kinase B – Forkhead box O signaling pathway Analyse
van de proteine kinase B – Forkhead box O signaleringsroute ...
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Der Transkriptionsfaktor FKHR interagiert mit STAT-Faktoren und verstaerkt die IL-6- …
DM genehmigte Dissertation, F Feld, H … - sylvester.bth.rwth-aachen.de
... Kortylewski, M.*, Feld, F.*, Krüger, KD, Bahrenberg, G., Roth, RA, Joost, HG, Heinrich,
PC, Behrmann, I., Barthel, A. (2003) Akt modulates STAT3-mediated gene ...
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POSTER SESSIONS ABSTRACTS
EEOFPT KINASE, B CELLULAR, RTDOFTNF RECEPTORS, … - dx.doi.org
... We focused our studies on Stat3, whose role in cancer has received significant
attention. ... Mu- tations of NESs identified in Stat1 were introduced into Stat3. ...
Web Search - liebertonline.com - liebertonline.com

SIAPEC IAP Societa Italiana International Academy di Anatomia Patologica e of Pathology …
B Board, GI di Immunoistochimica, GI di Patologia - springerlink.com
Page 1. 339 Page 2. SIAPEC IAP Società Italiana International Academy di Anatomia
Patologica e of Pathology Citopatologia Diagnostica Italian Division ...
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Prognostic Value of CD40 in Adult Soft Tissue Sarcomas - Full text - MIT Libraries
A Ottaiano, A De Chiara, F Perrone, G Botti, F … - Clinical Cancer Research, 2004 - intl-clincancerres.aacrjournals.org
... metalloproteinases-1 in cervical carcinoma cells: imbalance between NF- B and STAT3
activation ... Full Text]; Sorensen PH, Lynch JC, Qualman SJ, et al PAX3-FKHR and ...
Web Search - intl-clincancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
... ARE ARE EGR (1) EGR (1) HNF-4 HNF-4 NF-E2 NF-E2 PRE PRE Stat1 Stat1 USF-1 USF-1
6 Br n-3 Br n-3 ERE ERE IRF-1 IRF-1 NFkB NFkB RAR(DR5) RAR(DR5) Stat3 Stat3 VDR ...
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Genetics of Soft Tissue Tumors
J Lasota - elsevierinternational.com
... 83 t(12;22)(q13;q12) EWS-CHOP Rhabdomyosarcoma, alveolar t(2;13)(q35;q14)
PAX3-FKHR 101–104 t(1;13)(p36;q14) PAX7-FKHR Synovial ...
View as HTML - Web Search - harcourt-international.com - elsevier-international.com - intl.elsevierhealth.com - all 6 versions »

Gene-engineered models for genetic manipulation and functional analysis of the cardiovascular system …
PH Chu, JT Lu, J Chen - Chang Gung Med J, 2003 - cgmh.org.tw
... NT-3, trkCreceptor, dHAND, hox1.5, Sox4, rae28, NFH-1, NF-1, neuropilin, Pax3, RXRα,
connexin43 ... Gαq, Gq, Ras, RhoA, rac1, PKCβ2, NF-AT3, IL-6, STAT3, IGF-1B ...
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Identification of novel targets of the Forkhead transcription factor FKHR-L1 by gene array analysis
PF Dijkers, JWJ Lammers, L Koenderman, PJ Coffer - library.uu.nl
... DN, Sublett, JE, Li, B., Downing, JR & Naeve, CW Fusion of PAX3 to a member ... JA, Lammers,
JW, Koenderman, L. & de Groot, RP Activation of the STAT3/acute phase ...
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Transcriptional control in myelinating glia: Flavors and spices - Full text - MIT Libraries
M Wegner - Glia, 2000 - doi.wiley.com
... transcription factors have been identi- fied over the years that exhibit preferential
expression in myelinating glia and their progenitors, such as Pax3, Tst-1 ...
Cited by 24 - Web Search - doi.wiley.com - biochem.uni-erlangen.de - ncbi.nlm.nih.gov

MELANOCYTES AND THE MICROPHTHALMIA TRANSCRIPTION FACTOR NETWORK - Full text - MIT Libraries
E Steingrimsson, NG Copeland, NA Jenkins - Annual Review of Genetics, 2004 - arjournals.annualreviews.org
... 24, 87, 189). The transcription factors include Lef-1, Pax3, Sox10, CREB,
and Onecut-2 (22, 81, 149 189 203). All these pathways ...
Cited by 7 - Web Search - arjournals.annualreviews.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays Cat. # MA1010, MA1011, MA1012 Product User
Manual, MA1013 & MA1014, MA1015 Released 09/28/04 Panomics, Inc. ...
View as HTML - Web Search - biocat.de

The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation - Full text - MIT Libraries
LP Van Der Heide, MF Hoekman, MP Smidt - Biochem. J, 2004 - biochemj.org
... Initial studies on FoxO factors were performed on fusions of PAX3 [1] or PAX7 [2]
to FKHR (forkhead in rhabdomyosarcoma) which results in a transcription ...
Cited by 12 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

PROGRAM AND ABSTRACTS
A Meeting, STJ Meeting, F Miami - dx.doi.org
... W-4-7 5:00 PM “STAT3: A tale of multiple NESs” Samita Bhattacharya 1 and Christian
Schindler, 1,2 Departments of Microbiology 1 and Medicine, 2 College of ...
Cited by 2 - Web Search - liebertonline.com - ispp.org.il - societymusictheory.org - all 9 versions »

Protein-Protein-Interaktionen des G-CSFR
D der Naturwissenschaften, DBA Mohr - deposit.ddb.de
Page 1. Protein-Protein-Interaktionen des G-CSFR Vom Fachbereich Chemie der Universität
Hannover zur Erlangung des Grades Doktorin der Naturwissenschaften ...
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[BOOK] Function of PIAS proteins in steroid receptor-dependent signaling
N Kotaja - 2002 - ethesis.helsinki.fi
... PIAS3 (protein inhibitor of activated Stat3) was demonstrated to interact with
Stat3 and inhibit Stat3-dependent signaling (Chung et al. 1997). ...
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Stimulation of myelin gene expression in vitro and of sciatic nerve remyelination by interleukin-6 … - Full text - MIT Libraries
S Haggiag, PL Zhang, G Slutzky, V Shinder, A Kumar … - Journal of Neuroscience Research, 2001 - doi.wiley.com
Page 1. Stimulation of Myelin Gene Expression In Vitro and of Sciatic Nerve
Remyelination by Interleukin-6 Receptor–Interleukin-6 Chimera ...
Cited by 10 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma - Full text - MIT Libraries
K Khaleghpour, Y Li, D Banville, Z Yu, SH Shen - Carcinogenesis, 2003 - carcin.oupjournals.org
... RK and Lin,J. (2000) Elevated phosphorylation of Akt and Stat3 in prostate ... Regulation
of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion ...
Cited by 6 - Web Search - carcin.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Transcriptional control during mammalian anterior pituitary development - Full text - MIT Libraries
JJ Savage, BC Yaden, P Kiratipranon, SJ Rhodes - Gene, 2003 - www-unix.oit.umass.edu
Page 1. Review Transcriptional control during mammalian anterior pituitary development
Jesse J. Savage, Benjamin C. Yaden, Parinda Kiratipranon, Simon J. Rhodes ...
Cited by 7 - View as HTML - Web Search - ncbi.nlm.nih.gov

Univ. of Pennsylvania-Electronic Theses and Dissertations
AS Agbe-Davies, K Aker, LM Anderson, R Anisfeld, … - repository.upenn.edu
Univ. of Pennsylvania - Electronic Theses and Dissertations.
Browse by Year: 2004. Author Last Name: ...
Cached - Web Search - repository.upenn.edu

Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary … - Full text - MIT Libraries
D Fitzsimmons, R Lutz, W Wheat, HM Chamberlin, J … - Nucleic Acids Research, 2001 - nar.oupjournals.org
... 8–10). Competition was not observed when STAT3 binding sites were added at
3000-fold molar excess (lanes 11 and 12). Together, these ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

The Drosophila trithorax group gene tonalli (tna) interacts genetically with the Brahma remodeling … - Full text - MIT Libraries
L Gutierrez, M Zurita, JA Kennison, M Vazquez - Development, 2003 - dev.biologists.org
... Chung, CD, Liao, J., Liu, B., Rao, X., Jay, P., Bertha, P. and Shuai, K. (1997).
Specific inhibition of Stat3 signal transduction by PIAS3. ...
Cited by 6 - Web Search - dx.doi.org - dev.biologists.org - ncbi.nlm.nih.gov - all 5 versions »

Melanin pigmentation in mammalian skin and its hormonal regulation - Full text - MIT Libraries
A Slominski, DJ Tobin, S Shibahara, J Wortsman - Physiol Rev, 2004 - physrev.physiology.org
Institution: Google Indexer Sign In as Member/Non-Member. Physiol. Rev. 84:
1155-1228, 2004; 10.1152/physrev.00044.2003 0031-9333/04 $15.00 ...
Cited by 10 - Web Search - physrev.physiology.org - ncbi.nlm.nih.gov

Integrin Activates Receptor-Like Protein Tyrosine Phosphatase {alpha}, Src, and Rho to Increase … - Full text - MIT Libraries
AI Vulin, KK Jacob, FM Stanley, KC Center, FM … - Endocrinology, 2005 - endo.endojournals.org
Endocrine Society Endocrinology NCI RAPID Program ...
Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

Bibliography Current World Literature
EK Akpek, I Ahmed, FH Hochberg… - Current Opinion in Oncology, 2001 - co-oncology.com
May 2001, 13:3 > Bibliography Current World Literature. < Previous | Next >.
ARTICLE LINKS: Permissions | View full size inline images. ...
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Platinum Benefactors
B Sponsors - sidnet.org
Page 1. 1 Sponsors S PON SO RS Platinum Benefactors Allergan Skin Care Amgen Inc.
Biogen, Inc. Dermik Laboratories Fujisawa Healthcare, Inc. Galderma Genentech ...
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