Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an … - Full text - MIT Libraries
J Viti, A Feathers, J Phillips, L Lillien - J. Neurosci, 2003 - jneurosci.org
... Key words: EGF receptor; LIF; astrocyte; cortex; STAT3; stem cell; PAX6; BMP4.
Copyright © 2003 Society for Neuroscience 0270-6474/03/2383385-09$05.00/0. ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

S9-P82 Analysis of the role of Stat3 in mouse eye
AH Hart, F Melet, P Grossfeld, K Chien, A … - Analysis - blackwell-synergy.com
... To analyze the role of Stat3 in eyes, we generated retina or lens-specific
stat3-KO mice by ... We further found that Pax6 mutants are devoid of Raldh-3 expression ...
Web Search - Get it from MIT Libraries

Characterization of the roles of STAT1 and STAT3 signal transduction pathways in mammalian lens … - Full text - MIT Libraries
S Ebong, AB Chepelinsky, ML Robinson, H Zhao, CR … - Mol Vis, 2004 - molvis.org
... control of an αA-crys- tallin promoter modified by the insertion of a Pax6 consensus
binding element (unpublished). The floxed STAT3 DNAfrag- ment is deleted ...
Cited by 1 - View as HTML - Web Search - molvis.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular aspects of vertebrate retinal development
SS Zhang, XY Fu, CJ Barnstable - Mol. Neurobiol, 2002 - biomed.humanapress.com
... Another transcription factor, Pax6, is vital in very early development and ... The
intracellular signaling molecule Stat3 shows a pattern of expression during ...
Cited by 9 - Web Search - neurosci.humanapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

ROCK and Nuclear Factor-{kappa} B–dependent Activation of Cyclooxygenase-2 by Rho GTPases: Effects … - Full text - MIT Libraries
SA Benitah, PF Valeron, JC Lacal - Mol Biol Cell, 2003 - molbiolcell.org
... Rho proteins regulate transcription via several transcription factors that include
SRF, NF- B, E2F, Stat3, Stat5a, Pax6, FHL-2, Estrogen Receptor / , ELK, PEA3 ...
Cited by 7 - Web Search - molbiolcell.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Directing pluripotent cell differentiation using“diced RNA” in transient transfection - Full text - MIT Libraries
L Carpenter, M Zernicka-Goetz - genesis, 2004 - doi.wiley.com
... by RT-PCR also revealed increased lev- els of Pax6 transcripts, a ... dsiRNA to Stat3,
which maintains ES cell pluripotency and fate commitment (Niwa et al., 1998 ...
Web Search - ncbi.nlm.nih.gov

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells - Full text - MIT Libraries
RH Xu, RM Peck, DS Li, X Feng, T Ludwig, JA … - Nature Methods, 2005 - nature.com
... Id genes 7 . Addition of LIF to culture medium 1 or activation of Stat3 (ref. ... Neither
the neural progenitor markers PAX6 and NEUROD1; T, a homolog of the mouse ...
Cited by 7 - Web Search - nature.com - ncbi.nlm.nih.gov

Pituitary Development: Regulatory Codes in Mammalian Organogenesis - Full text - MIT Libraries
S Regulation - Science, 2002 - sciencemag.org
... Thus, Pax6 may functionally oppose Shh signaling to specify a dorsal rather than
ventral ... and Egr-1 (38) (gonadotropes); and T-pit and possibly STAT3 (POMC gene ...
Web Search - mcb.berkeley.edu - pharmacology.case.edu - pharmacology.cwru.edu - all 5 versions »

Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor–induced … - Full text - MIT Libraries
T Setoguchi, T Kondo - The Journal of Cell Biology - jcb.org
... Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of ... Regionalization
and fate specification in neurospheres: the role of Olig2 and Pax6. Mol. ...
Cited by 1 - Web Search - jcb.org - ncbi.nlm.nih.gov

Serum-free culture of rhesus monkey embryonic stem cells.
Y PEI, J MA, X ZHANG, W JI - Archives of Andrology, 2003 - taylorandfrancis.metapress.com
... Furthermore, transcripts of PAX6, BMP4, and CGa were also detected in the rES ... molecules
of LIF required for mouse ES cell growth, including STAT3, are already ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural … - Full text - MIT Libraries
J Aubert, H Dunstan, I Chambers, A Smith, S Table, … - Nature Biotechnology, 2002 - nature.com
... renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. ... |
Article | PubMed | ISI | ChemPort |; Walther, C. & Gruss, P. Pax6, a murine ...
Cited by 41 - Web Search - nature.com - era.lib.ed.ac.uk - ncbi.nlm.nih.gov

BMP4 and CNTF are neuroprotective and suppress damage-induced proliferation of Mueller glia in the … - Full text - MIT Libraries
AJ Fischer, M Schmidt, G Omar, TA Reh - Mol. Cell. Neurosci, 2004 - faculty.washington.edu
... We have shown previously that these proliferating Pax6-expressing cells are derived ...
and stress stimuli induce the accumulation of activated STAT3 in Mqller glia ...
View as HTML - Web Search - ncbi.nlm.nih.gov

Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate … - Full text - MIT Libraries
H Tiedemann, M Asashima, H Grunz, W Knochel - Dev. Growth Differ, 2001 - blackwell-synergy.com
... Cell type-specific interpretation of STAT3 activation may explain its diverse
developmental ... The expression of the Pax6 homeobox gene in the chicken neural ...
Cited by 13 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Basic and clinical neuroscience applications of embryonic stem cells
S GOKHAN, MD MEHLER - THE ANATOMICAL RECORD (NEW ANAT.), 2001 - doi.wiley.com
... STAT3, an acute phase response factor activated by sev- eral different cytokine
subclasses ... of genes involved in neural tube pattern- ing (Pax6) and neurogenesis ...
Cited by 11 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal … - Full text - MIT Libraries
AF Muro, AK Chauhan, S Gajovic, A Iaconcig, F … - J Cell Biol, 2003 - jcb.org
... of alternatively spliced exons in different protein systems such as 6 integrin,
-aminobutyrate receptor, dopamine D2 receptor, FN, Pax6, and Stat3 (Gimond et al ...
Cited by 17 - Web Search - dx.doi.org - jcb.org - ncbi.nlm.nih.gov - all 5 versions »

TRANSGENESIS AND GENE TARGETING
EG ENGINEERS - kcl.ac.uk
... requires Oct4, Sox2, and FoxD3 In the ES cell Oct4, Sox2, Stat3, and Nanog ... En2
Mid/hindbrain lacZ Wnt1 Neural crest lacZ Camk2a Forebrain Hdh Pax6 Retina Pax6 ...
View as HTML - Web Search

IL-6 Plays a Unique Role in Initiating c-Maf Expression during Early Stage of CD4 T Cell Activation - Full text - MIT Libraries
Y Yang, J Ochando, A Yopp, JS Bromberg, Y Ding - The Journal of Immunology, 2005 - jimmunol.org
... To determine whether Stat3 transactivates the c-maf promoter, the c-maf promoter
was ... fibroblast cell line C3H10T1/2. Both c-Maf itself and Pax6 activate the c ...
Cited by 1 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Induction of Ectopic Olfactory Structures and Bone Morphogenetic Protein Inhibition by Rossy, a … - Full text - MIT Libraries
I Munoz-Sanjuan, AH Brivanlou - Mol Cell Biol, 2005 - mcb.asm.org
... not express Pax6, suggesting a non-cell-autonomous effect on Pax6 expression ... pathways
and basic fibroblast growth factor (bFGF)/Ras, Wnt, or Stat3 signaling in ...
Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Abstracts of papers presented at the tenth Mammalian Genetics and De elopment Workshop ( …
S HUXTABLE, P SAKER, L HADDAD, A HATTERSLEY - journals.cambridge.org
... Together, these results demonstrate requirements for functional Pax6 in both the
optic ... Of these, activation of the latent transcription factor Stat3 has been ...
Web Search

Transcriptional Control of the Cell Cycle in Mammary Gland Development and Tumorigenesis
RD Coletta, P Jedlicka, A Gutierrez-Hartmann, HL … - Journal of Mammary Gland Biology and Neoplasia, 2004 - springerlink.com
... Six3 is able to rescue the small eye phenotype in Pax6 haploinsufficient mice ... There
are seven STAT genes in mammals (STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B ...
Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

14th International Congress on Developmental Biology S45
JM Miller, DK Hoshizaki, AC Wizenmann, AGS Lumsden - blackwell-synergy.com
... S2-P5 The spatio-temporal pattern of Pax6 and Notch expression during newt retinal
regeneration Yuko Kaneko, 1 Yoshiro Hanyu, 2 Kiyonori Hirota, 2 Gen ...
Web Search

MAP kinases - Full text - MIT Libraries
Z Chen, TB Gibson, F Robinson, L Silvestro, G … - Chem. Rev, 2001 - audreyli.com
Page 1. MAP Kinases Zhu Chen, † Tara Beers Gibson, Fred Robinson, Loraine
Silvestro, Gray Pearson, Bing-e Xu, Angelique Wright, Colleen ...
Cited by 70 - View as HTML - Web Search - ncbi.nlm.nih.gov

Conditional alleles in mice: Practical considerations for tissue-specific knockouts - Full text - MIT Libraries
KM Kwan - genesis, 2002 - doi.wiley.com
... Pax5 4 (20.7) F Horcher et al., 2001 Pax6 2 (58.0) ✚ Ashery-Padan et al., 2000;
Marquardt et al., 2001 Pex5 ... unknown F Wiebel et al., 2002* Stat3 ...
Cited by 27 - Web Search - tagc.univ-mrs.fr - biochem.wisc.edu - ncbi.nlm.nih.gov - all 6 versions »

Monoclonal Antibody Defining a Stage-Specific Mouse Embryonic Antigen (SSEA-1) - Full text - MIT Libraries
D Solter, BB Knowles - Glycobiology, 2005 - pnas.org
... N. Takashima, Y. Ishii, S. Nakamura, N. Osumi, and Y. Sanai Pax6 Controls the ... K.
Nakao, T. Arai, M. Katsuki, T. Heike, and T. Yokota STAT3 activation is ...
Cited by 218 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

JCB Article - Full text - MIT Libraries
AF Muro, AK Chauhan, S Gajovic, A Iaconcig, F … - The Journal of Cell Biology, 2003 - icbxs.ethz.ch
... grin, -aminobutyrate receptor, dopamine D2 receptor, FN, Pax6, and Stat3 (Gimond
et al., 1998; Homanics et al., 1999; Usiello et al., 2000; Wang et al., 2000 ...
View as HTML - Web Search

Regulation of insulin gene transcription - Full text - MIT Libraries
D Melloul, S Marshak, E Cerasi - Diabetologia, 2002 - springerlink.com
... This C2 element binds the tran- scription factors containing a paired domain and
a homeodomain, PAX6 which acts as a transactivator [77] and PAX4 as a ...
Cited by 37 - Web Search - ncbi.nlm.nih.gov

Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell - Full text - MIT Libraries
L Conti, SM Pollard, T Gorba, E Reitano, M Toselli … - PLoS Biol, 2005 - biology.plosjournals.org
... Gfap (P03995), Nanog (Q7TN85), Nestin (Q6P5H2), Olig2 (Q9EQW6), Pax6 (P63015), Pax7 ...
and sustains embryonic stem cell self-renewal in collaboration with STAT3. ...
Cached - Web Search - plme.allenpress.com - plbi.allenpress.com - pubmedcentral.nih.gov - all 5 versions »

A mouse model for visualization and conditional mutations in the erythroid lineage - Full text - MIT Libraries
AC Heinrich, R Pelanda, U Klingmuller - Blood, 2004 - bloodjournal.org
... 2) and the signal transducer and activator of transcription 3 (STAT3), 13 which
is ... for different cis-regulative elements in paired box gene 6 (PAX6) intron 7 ...
Cited by 5 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The role of Wilms’ tumor genes - Full text - MIT Libraries
M Hirose - J Med Invest, 1999 - med.tokushima-u.ac.jp
... The WT1 and aniridia gene of Pax6 are located at band 11p13, and ... inducing signal
mediated by G-CSF receptor and constitutively activated Stat3, resulting in ...
Cited by 17 - View as HTML - Web Search - medical.med.tokushima-u.ac.jp - ncbi.nlm.nih.gov

Gene expression in human neural stem cells: effects of leukemia inhibitory factor - Full text - MIT Libraries
LS Wright, J Li, MA Caldwell, K Wallace, JA … - Journal of Neurochemistry, 2003 - blackwell-synergy.com
... signal transducer and activator of transcription 1 and 3 (STAT1, STAT3) were modulated ...
PAX6, which is known to play a role in cortical neurogenesis, was also ...
Cited by 29 - Web Search - ingentaconnect.com - cnc.cj.uc.pt - med.usf.edu - all 9 versions »

Activation of Stem-Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34 Human Cord …
CM Ferrell, ST Dorsam, H Ohta, RK Humphries, MK … - stemcells.alphamedpress.org
... Chauhan BK, Zhang W, Cveklova K et al. Identification of differentially expressed
genes in mouse Pax6 heterozygous lenses. ... Tip 60 is a co-repressor for STAT3. ...
Web Search - dx.doi.org - stemcells.alphamedpress.org

A comparative analysis of relative occurrence of transcription factor binding sites in vertebrate … - Full text - MIT Libraries
M Stepanova, T Tiazhelova, M Skoblov, A Baranova - Bioinformatics, 2005 - bioinformatics.oxfordjournals.org
... matches in sequence of study was underestimated previously, especially for PAX6
and COMP1 ... On the other hand, binding sites for factors STAT1, STAT3 and V-JUN ...
Web Search - bioinformatics.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs - Full text - MIT Libraries
M Kasai, K Satoh, T Akiyama - Genes to Cells, 2005 - blackwell-synergy.com
... Neuronal differentiation is regulated by the bHLH proteins neurogenin 1 and 2 as
well as the homeodomain proteins Pax6 and Emx (Schuurmans & Guillemot 2002 ...
Web Search - ingentaconnect.com - genestocellsonline.org

Regulatory genes controlling cell fate choice in embryonic and adult neural stem cells - Full text - MIT Libraries
RMR Gangemi, M Perera, G Corte - Journal of Neurochemistry, 2004 - blackwell-synergy.com
... decisions during corticogenesis has focused recently on two genes already involved
in the regional identity specification of dorsal telencephalon: Pax6 and Emx2 ...
Cited by 3 - Web Search - ingentaconnect.com - biox.cn - ncbi.nlm.nih.gov - all 6 versions »

Transcriptional control during mammalian anterior pituitary development - Full text - MIT Libraries
JJ Savage, BC Yaden, P Kiratipranon, SJ Rhodes - Gene, 2003 - www-unix.oit.umass.edu
... 3.1.3. PAX6 The Pax6 gene encodes a conserved PAX-class transcrip- tion factor
containing both a paired DNA binding domain and a paired-class homeodomain. ...
Cited by 7 - View as HTML - Web Search - ncbi.nlm.nih.gov

Abstracts of Communications of the 45 thAnnual Meeting of the Japanese Society for Neurochemistry
SPRBY STARGAZIN, N FUNCTION, I TRANSPORT, ASALORD … - Neurochemical Research, 2003 - springerlink.com
Page 1. Abstracts of Communications of the 45 th Annual Meeting of the
Japanese Society for Neurochemistry 1063 0364-3190/03/0700 ...
Web Search - kluweronline.com

Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary … - Full text - MIT Libraries
D Fitzsimmons, R Lutz, W Wheat, HM Chamberlin, J … - Nucleic Acids Research, 2001 - nar.oupjournals.org
... Competition was not observed when STAT3 binding sites were added at 3000-fold molar ...
Maas,RL and Pabo,CO (1999) Crystal structure of the human Pax6 paired domain ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

TranSignal TM GR-TF Interaction Arrays
PU Manual - panomics.com
... ARE ARE EGR (1) EGR (1) HNF-4 HNF-4 NF-E2 NF-E2 PRE PRE Stat1 Stat1 USF-1 USF-1
6 Br n-3 Br n-3 ERE ERE IRF-1 IRF-1 NFkB NFkB RAR(DR5) RAR(DR5) Stat3 Stat3 VDR ...
View as HTML - Web Search - biocat.de

The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition - Full text - MIT Libraries
M Melnick, H Chen, Y Min Zhou, T Jaskoll - BMC Developmental Biology, 2001 - biomedcentral.com
... c-Raf [55a]. Further, both the SHP-2/Ras and JAK/STAT3 pathways are activated
by IL-6R/gp130 signaling (Fig. 1). Moreover, it is ...
Cited by 10 - Cached - Web Search - dx.doi.org - pubmedcentral.nih.gov - genomebiology.com - all 12 versions »

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... OCT1 Q6 Octamer factor 1 P300 01 p300 PAX3 B Pax3 binding sites PAX4 01 Pax-4 binding
sites PAX4 03 Pax-4 binding sites PAX4 04 Pax-4 binding sites PAX6 01 Pax ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

EGL-38 Pax regulates the ovo-related gene lin-48 during Caenorhabditis elegans organ development - Full text - MIT Libraries
AD Johnson, D Fitzsimmons, J Hagman, HM Chamberlin - Development, 2001 - dev.biologists.org
... Competition was not detected using lre1 DNA, or by control STAT3-binding sites ... Crystal
structure of the human Pax6 paired domain-DNA complex reveals specific ...
Cited by 12 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Untitled
dx.doi.org
1. Yarranton, GT Inducible vectors for expression in mammalian cells. Curr. Opin.
Biotechnol. 3, 506-511 (1992). | PubMed | ChemPort |. 2. Khillan, JS et al. ...
Cited by 146 - milkpa.idv.tw - fbmc.fcen.uba.ar - neuroscience.unc.edu - all 13 versions »

TranSignal TM Protein/DNA Arrays
CS Version - panomics.com
... ARE ARE EGR (1) EGR (1) HNF-4 HNF-4 NF-E2 NF-E2 PRE PRE Stat1 Stat1 USF-1 USF-1
6 Br n-3 Br n-3 ERE ERE IRF-1 IRF-1 NFkB NFkB RAR(DR5) RAR(DR5) Stat3 Stat3 VDR ...
View as HTML - Web Search

Oct-4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in … - Full text - MIT Libraries
DC Hay, L Sutherland, J Clark, T Burdon - Stem Cells, 2004 - intl-stemcells.alphamedpress.org
... of FGF5, (a primitive ectoderm marker), Brachyury (mesoderm), or Pax6 (embryonic
ectoderm ... Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by ...
Cited by 12 - Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov - all 7 versions »

Oct-3/4 Maintains the Proliferative Embryonic Stem Cell State via Specific Binding to a Variant … - Full text - MIT Libraries
M Nishimoto, S Miyagi, T Yamagishi, T Sakaguchi, H … - Mol Cell Biol, 2005 - mcb.asm.org
... bp 376 to 604; Brachyury (T), bp 1763 to 1921; Pax6, bp 1045 ... STAT3 activation is
sufficient to maintain an undifferentiated state of mouse embryonic stem cells ...
Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Directed differentiation of embryonic stem cells: Genetic and epigenetic methods - Full text - MIT Libraries
K O'SHEA - Wound Repair and Regeneration, 2001 - blackwell-synergy.com
... that have a critical function in differentiation are members of the GATA family
of transcription factors, particularly GATA-4 and GATA-6, 26,27 Stat3, 28 and ...
Cited by 8 - Web Search - ncbi.nlm.nih.gov

TranSignal TM Protein/DNA Arrays
PU Manual, MA MA1014 - panomics.com
Page 1. TranSignal TM Protein/DNA Arrays Cat. # MA1010, MA1011, MA1012 Product User
Manual, MA1013 & MA1014, MA1015 Released 09/28/04 Panomics, Inc. ...
View as HTML - Web Search - biocat.de

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
Page 1. Molecular Vision 2004; 10:163-76 <http://www.molvis.org/molvis/v10/a22>
Received 3 October 2003 | Accepted 16 March 2004 | Published 22 March 2004 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

MELANOCYTES AND THE MICROPHTHALMIA TRANSCRIPTION FACTOR NETWORK - Full text - MIT Libraries
E Steingrimsson, NG Copeland, NA Jenkins - Annual Review of Genetics, 2004 - arjournals.annualreviews.org
... Baumer and associates (10) subsequently showed that optic vesicle-expressed Pax2
and Pax6 are necessary for Mitf expression during eye development and can bind ...
Cited by 7 - Web Search - arjournals.annualreviews.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

BMC Developmental Biology - Full text - MIT Libraries
M Melnick, H Chen, YM Zhou, T Jaskoll - BMC Developmental Biology, 2001 - biomedcentral.com
... c-Raf [55a]. Fur- ther, both the SHP-2/Ras and JAK/STAT3 pathways are
activated by IL-6R/gp130 signaling (Fig. 1). Moreover, it ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de - usc.edu