JAK/STAT but not ERK1/ERK2 pathway mediates IL-6/sIL-6R down-regulation of type II collagen, … - Full text - MIT Libraries
F Legendre, J Dudhia, JP Pujol, P Bogdanowicz - Cancer Res, 2005 - jbc.org
... soluble receptor (sIL-6R), induces activation of JAK1, JAK2, and STAT1/STAT3 proteins
in ... genes by IL-6. In addition, a parallel reduction of SOX9 expression, a ...
Web Search

S9-P82 Analysis of the role of Stat3 in mouse eye
AH Hart, F Melet, P Grossfeld, K Chien, A … - Analysis - blackwell-synergy.com
... S9-P82 Analysis of the role of Stat3 in mouse eye Akihiko Muto, 1 Yutaka Aoki, 1
Hiroshi Sagara, 2 Kiyoshi Takeda, 3 Shizuo Akira, 3 Ken-ichi Arai, 1 Sumiko ...
Web Search - Get it from MIT Libraries

Different contributions of STAT3, ERK1/2, and PI3-K signaling to cardiomyocyte hypertrophy by …
T Ze-jun, CUI Wei, LI Yong-jun, HAO Yu-ming, DU … - chinaphar.com
... in articular chondrocytes: association with a down-regulation of sox9 expression. ...
signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2 ...
View as HTML - Web Search - chinaphar.com

Mini Review New insights in congenital bowing of the femora - Full text - MIT Libraries
V Cormier-Daire, D Genevieve, A Munnich, M Le … - Clinical Genetics, 2004 - blackwell-synergy.com
... due to LIFR mutations, Compomelic dysplasia due to SOX9 mutations and ... By Western
blot and immunofluorescence analysis using an antiphospho STAT3 antibody in ...
Web Search - blackwell-synergy.com

JAK/STAT but Not ERK 1/ERK 2 Pathway Mediates Interleukin(IL)-6/Soluble IL-6 R Down-regulation of … - Full text - MIT Libraries
F Legendre, J Dudhia, JP Pujol, P Bogdanowicz - J Biol Chem, 2003 - jbc.org
... F-2 or C-20), anti-phosphospecific STAT1-Tyr 701 (A-2), STAT3-Tyr 705 ... Rabbit polyclonal
anti-Sox9 antibody was kindly provided by B. de Crombrugghe (Department ...
Cited by 7 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A decade of site- and phosphorylation state-specific antibodies: recent advances in studies of … - Full text - MIT Libraries
K Nagata, I Izawa, M Inagaki - Genes to Cells, 2001 - genestocellsonline.org
... 1999 63 Stat3 Ser727 ? ... Chk2/Cds1 Ser68 ATM kinase ATM kinase SOX9 transcription factor
Ser211 PKA enhance transcriptional and DNA-binding activity of SOX9 ...
Cited by 5 - Web Search - ingentaconnect.com - genestocellsonline.org - ncbi.nlm.nih.gov

Multiple functions of BMPs in chondrogenesis - Full text - MIT Libraries
BS Yoon, KM Lyons - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... mechanisms underlying the ability of BMP signaling to maintain Sox9 expression are ...
that BMPs can inhibit the phosphorylation and activation of STAT3 by an ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon- … - Full text - MIT Libraries
M Osaki, L Tan, BK Choy, Y Yoshida, KS Cheah, PE … - Biochem. J, 2003 - biochemj.org
... mRNA levels by IFN-γ and that changes in the levels of Sox9 and related ... Antibody
against either Stat2 or Stat3 did not alter the pattern of binding to this ...
Cited by 15 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Glial specification in the vertebrate neural tube - Full text - MIT Libraries
DH Rowitch - Nature Reviews Neuroscience, 2004 - nature.com
1. Ramón y Cajal, S. Histologie du Systeme Nerveux de l'Homme et des
Vertebres (Consejo Superior de Investigaciones Cientificas ...
Cited by 7 - Web Search - cb207.med.harvard.edu - cellbio.wustl.edu - ncbi.nlm.nih.gov - all 5 versions »

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity - Full text - MIT Libraries
D Schmidt, S Mueller - J. Biol. Chem, 2005 - dx.doi.org
... SF-1) Regulates Synergistic Transcription between Ad4BP/SF-1 and Sox9 Mol. ... of Smad
transcriptional activity by protein inhibitor of activated STAT3 (PIAS3) PNAS ...
Cited by 92 - Web Search - pnas.org - pubmedcentral.gov - ncbi.nlm.nih.gov - all 6 versions »

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex - Full text - MIT Libraries
JD Fondell, H Ge, RG Roeder - Biochemistry, 1996 - dx.doi.org
... STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full
transcriptional ... Scherer, RG Roeder, F. Poulat, and P. Berta SOX9 interacts with ...
Cited by 233 - Web Search - pnas.org - biochem.med.umich.edu - ncbi.nlm.nih.gov - all 7 versions »

Constitutive activation of MEK 1 in chondrocytes causes Stat 1-independent achondroplasia-like … - Full text - MIT Libraries
S Murakami, G Balmes, S McKinney, Z Zhang, D Givol … - Genes & Development, 2004 - genesdev.org
... for collagen type X and persistent expression of Sox9 in chondrocytes ... to activate
multiple signal transduction pathways; these include Stat1, Stat3, Stat5, ERK1 ...
Cited by 8 - Web Search - genesdev.org - pubmedcentral.nih.gov - dx.doi.org - all 7 versions »

Sustained ERK 1/2 but not STAT 1 or 3 activation is required for thanatophoric dysplasia phenotypes … - Full text - MIT Libraries
N Nowroozi, S Raffioni, T Wang, BL Apostol, RA … - Human Molecular Genetics, 2005 - hmg.oxfordjournals.org
... STAT1, STAT3, STAT5b and p21 WAF1/CIP1 were from Santa Cruz Biotechnology and ... WL
and de Crombrugghe, B. (2000) Up-regulation of the chondrogenic Sox9 gene by ...
Web Search - hmg.oxfordjournals.org - hmg.oupjournals.org - ncbi.nlm.nih.gov

Hypothesis: sex determination and germline formation are committed at the pronucleate stage in … - Full text - MIT Libraries
RG Edwards, HK Beard - Molecular Human Reproduction, 1999 - molehr.oupjournals.org
... body (Gardner, 1996 , 1997 ), and an anterior/posterior polarity was identified
in the distribution of the leptin (cytokine), and STAT3 (signal transducer and ...
Cited by 8 - Web Search - molehr.oupjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a … - Full text - MIT Libraries
S Miyake, M Makimura, Y Kanegae, S Harada, Y Sato, … - J. Biol. Chem, 2005 - dx.doi.org
... M. Detmar, and K. Hashimoto Nuclear Translocation of Phosphorylated STAT3 Is Essential ...
Chondrocyte-specific Gene Expression via Association with Sox9 J. Biol. ...
Cited by 460 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Identification of Neuronal Enhancers of the Proopiomelanocortin Gene by Transgenic Mouse Analysis … - Full text - MIT Libraries
FSJ de Souza, AM Santangelo, V Bumaschny, ME Avale … - Mol Cell Biol, 2005 - mcb.asm.org
... Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation ...
STAT3 signalling is required for leptin regulation of energy balance but not ...
Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Conditional alleles in mice: Practical considerations for tissue-specific knockouts - Full text - MIT Libraries
KM Kwan - genesis, 2002 - doi.wiley.com
... Smad4 (or Madh4) 18 (48.0) F Yang et al., 2002* Sox9 11 (69.5) F Kist et al., 2002*
Srf (serum response factor) unknown F Wiebel et al., 2002* Stat3 ...
Cited by 27 - Web Search - tagc.univ-mrs.fr - biochem.wisc.edu - ncbi.nlm.nih.gov - all 6 versions »

Embryonic brain‐gonadal axis in temperature‐dependent sex determination of reptiles: A role for … - Full text - MIT Libraries
P Jeyasuria, AR Place - The Journal of Experimental Zoology, 1998 - doi.wiley.com
... Two other genes involved in gonad cell lineage determination are the SRY-related
gene SOX9 and an unusual member of the nuclear hormone receptor superfamily ...
Cited by 26 - Web Search - doi.wiley.com

A slug, a fox, a pair of sox: Transcriptional responses to neural crest inducing signals
E Heeg-Truesdell, C LaBonne - Birth Defects Research Part C Embryo Today Reviews, 2004 - doi.wiley.com
Page 1. A Slug, a Fox, a Pair of Sox: Transcriptional Responses to Neural Crest
Inducing Signals Elizabeth Heeg-Truesdell* and Carole LaBonne ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

LESSONS IN ESTROGEN BIOLOGY FROM KNOCKOUT AND TRANSGENIC ANIMALS - Full text - MIT Libraries
SC Hewitt, JC Harrell, KS Korach - Annual Review of Physiology, 2005 - arjournals.annualreviews.org
... We examined some novel signals that were initiated and noted activation of
phospho-STAT3, a transcriptional activator that is a target for cytokine signal ...
Web Search - ncbi.nlm.nih.gov

Lessons IN Estrogen Biology FROM Knockout AND Transgenic Animals
A DV - arjournals.annualreviews.org
Page 1. 28 Sep 2004 18:22 AR AR237-PH67-07.tex AR237-PH67-07.sgm LaTeX2e(2002/01/
18) P1: IKH AR REVIEWS IN ADVANCE10.1146/annurev.physiol.67.040403.115914 ...
Web Search - arjournals.annualreviews.org

A statistical analysis of the TRANSFAC database.
GB Fogel, DG Weekes, G Varga, ER Dow, AM Craven, … - Biosystems, 2005 - natural-selection.com
... 4 binding sites PAX4 04 Pax-4 binding sites PAX6 01 Pax-6 PU1 B Pu.1 (Pu120)
Ets-like transcription factor identified in lymphoid B-cells S8 01 S8 SOX9 B1 SOX ...
View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulation of skeletal development by the Runx family of transcription factors - Full text - MIT Libraries
T Komori - Journal of Cellular Biochemistry, 2005 - doi.wiley.com
... The transcription factor Sox9 plays an essential role in mesenchymal condensation
leading to formation of the cartilaginous tem- plate; Sox5 and Sox6 are ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Mechanisms balancing skeletal matrix synthesis and degradation - Full text - MIT Libraries
HC Blair, M Zaidi, PH Schlesinger - Biochem. J, 2002 - biochemj.org
... The nuclear transcription factor Sox9 is required for cartilage differen- tiation;
its absence causes a lethal skeletal malformation, campo- melic dysplasia [29 ...
Cited by 17 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Regulatory genes controlling cell fate choice in embryonic and adult neural stem cells - Full text - MIT Libraries
RMR Gangemi, M Perera, G Corte - Journal of Neurochemistry, 2004 - blackwell-synergy.com
Page 1. Regulatory genes controlling cell fate choice in embryonic and adult neural
stem cells Rosaria Maria Rita Gangemi,* Marzia Perera* and Giorgio Corte* , ...
Cited by 3 - Web Search - ingentaconnect.com - biox.cn - ncbi.nlm.nih.gov - all 6 versions »

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
Page 1. Molecular Vision 2004; 10:163-76 <http://www.molvis.org/molvis/v10/a22>
Received 3 October 2003 | Accepted 16 March 2004 | Published 22 March 2004 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

Cellular Physiology and Biochemistry
V Dossinger, T Kayademir, N Blin, P Goett - Cell Physiol Biochem, 2002 - content.karger.com
... three TFF genes (Figure 3). Since we found no putative STAT3 binding sites ... de
Crombrugghe B: Potent inhibition of the master chondro- genic factor Sox9 gene by ...
Web Search - content.karger.com

Y o ur R e s o u r c e f o r T e
CN Notes - promega.com
Page 1. Page 2. P r o m e g a : Y o ur R e s o u r c e f o r T e c h n
i c a lI n fo r m a t i o n Our technical publications are ...
View as HTML - Web Search

Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP-2- … - Full text - MIT Libraries
E Balint, D Lapointe, H Drissi, C van der Meijden, … - Journal of Cellular Biochemistry, 2003 - doi.wiley.com
... Transcription factors that have been identified as BMP-2 responsive for skeletogen-
esis include Sox9, which is crucial for chondro- genesis and Cbfa1/Runx2 ...
Cited by 16 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Anti-inflammatory Properties of the Novel Antitumor Agent Yondelis (Trabectedin): Inhibition of … - Full text - MIT Libraries
P Allavena, M Signorelli, M Chieppa, E Erba, G … - Cancer Research, 2005 - cancerres.aacrjournals.org
... Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and
malignant human ovarian ... Association with a down-regulation of SOX9 expression. ...
Cited by 1 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Abstracts from the 4th Annual Conference on Mesenchymal and Non-Hematopoietic Stem Cells: Focus on …
S II, P SESSION - Cytotherapy, 2005 - taylorandfrancis.metapress.com
... The MSC nature of purified cells was further confirmed by real-time measurements
of transcription factors cbfa-1, Sox9 and PPARγ that were 10–100-fold ...
Web Search

25 thAnnual Minisymposium on Reproductive Biology
HG Inn - northwestern.edu
Page 1. Center for Reproductive Science 25 th Annual Minisymposium on
Reproductive Biology October 18, 2004 Hilton Garden Inn 1818 ...
View as HTML - Web Search

A Synthetic Inhibitor of the Mitogen-Activated Protein Kinase Cascade - Full text - MIT Libraries
DT Dudley, L Pang, SJ Decker, AJ Bridges, AR … - Proceedings of the National Academy of Sciences - pnas.org
Proceedings of the National Academy of Sciences, Vol 92, 7686-7689, Copyright ©
1995 by National Academy of Sciences. ARTICLE. A ...
Cited by 1517 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 5 versions »

FGF signaling pathways in endochondral and intramembranous bone development and human genetic … - Full text - MIT Libraries
DM Ornitz, PJ Marie - Development, 2002 - dx.doi.org
... mesenchymal cells, FGF signaling pathways induce the expression of SOX9, an essential ...
with FGF can induce nuclear translocation of STAT1 and STAT3 and induce ...
Cited by 77 - Web Search - genesdev.org - genesdev.org - ncbi.nlm.nih.gov - all 5 versions »

The Transcriptional Regulating Protein of 132 kDa(TReP-132) Enhances P 450 scc Gene Transcription … - Full text - MIT Libraries
F Gizard, B Lavallee, F DeWitte, E Teissier, B … - J Biol Chem, 2002 - jbc.org
... directly in the process of male sex determination, and synergizes with SOX9 and
WT1 ... as a "bridging molecule" in the positive cross-talk between STAT3 and Smad1 ...
Cited by 17 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Thirty-fourth Annual Scientific Meeting
P Stanton, P Sluka, L O’Donnell, GP Risbridger, … - publish.csiro.au
Page 1. Society for Reproductive Biology Thirty-fourth Annual Scientific
Meeting ABSTRACTS (Nos 1–110 in order of presentation) ...
Web Search

OPENING PLENARY LECTURES
S LECTURES - blackwell-synergy.com
Page 1. OPENING PLENARY LECTURES OP-1 Molecular basis of eye development
Peter Gruss, Gilbert Bernier, Till Marquardt, Xunlei Zhou ...
Web Search - bcasj.or.jp - ibvt.uni-stuttgart.de

Regulation and function of somatostatin receptors - Full text - MIT Libraries
G Olias, C Viollet, H Kusserow, J Epelbaum, W … - Journal of Neurochemistry, 2004 - blackwell-synergy.com
Full Article. View/Print PDF article (558K). Download to reference manager.
Journal of Neurochemistry Volume 89 Issue 5 Page 1057 - June ...
Cited by 5 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Communications Update
S Cells, DNA Repair, P Assay, C Signaling - Neuroscience - chemicon.com
... AB5995 Pdx-1 (Hu, Rodent) AB5999 Scratch/Scrt (Hu, Rodent) AB5801 Sox4 (Hu, Rodent)
AB5803 Sox6 (Hu, Rodent) AB5805 Sox8 (Hu, Rodent) AB5807 Sox9 (Hu, Rodent ...
View as HTML - Web Search - chemicon.com - Get it from MIT Libraries

Bibliography Current World Literature
S Aggarwal, Y Takada, S Singh… - Current Opinion in Oncology, 2005 - co-oncology.com
May 2005, 17:3 > Bibliography Current World Literature. ...
Web Search - co-cardiology.com