Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1 - Full text - MIT Libraries
CA Cantwell, E Sterneck, PF Johnson - Mol. Cell. Biol, 1998 - mcb.asm.org
... Interleukin-6-Specific Activation of the C/EBP Gene in Hepatocytes Is Mediated by
Stat3 and Sp1. Carrie A. Cantwell, Esta Sterneck, and Peter F. Johnson * ...
Cited by 55 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Stat3 and Stat4: Members of the Family of Signal Transducers and Activators of Transcription - Full text - MIT Libraries
Z Zhong, Z Wen, JE Darnell Jr - Proceedings of the National Academy of Sciences - pnas.org
... Home page CA Cantwell, E. Sterneck, and PF Johnson Interleukin-6-Specific Activation
of the C/EBPdelta Gene in Hepatocytes Is Mediated by Stat3 and Sp1 Mol. ...
Cited by 121 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Co-operative Effect of c-Src Tyrosine Kinase and Stat 3 in Activation of Hepatocyte Growth Factor … - Full text - MIT Libraries
W Hung, B Elliott - J Biol Chem, 2001 - jbc.org
... activated c-Src alone. This effect is probably due to a limiting amount of
endogenous Stat3 in SP1 cells. When both Stat3 and activated ...
Cited by 26 - Web Search - meds.queensu.ca - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Identification of a signal transducer and activator of transcription (STAT) binding site in the … - Full text - MIT Libraries
DK Lee, J Carrasco, J Hidalgo, GK Andrews - Biochem. J, 1999 - biochemj.org
... complex III. Complex II was not supershifted or inhibited with STAT1, STAT3
or Sp1 antisera (results not shown). Western blotting ...
Cited by 30 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

[CITATION] IL-6 induces transcriptional activation of vascular endothelial growth factor in astrocytes in vivo …
S Loeffler, B Fayard, J Weis, J Weissenberger - Int J Cancer (in press)
Cited by 1 - Web Search

Induction of Sp1 activity by prolactin and interleukin-2 in Nb2 T-cells: differential association of …
CK Too - Mol Cell Endocrinol, 1997 - ingentaconnect.com
... Electrophoretic mobility shift assays using an Sp1 consensus oligonucleotide as
probe ... using specific Stat antibodies failed to detect Stat1 , Stat3 or Stat5 in ...
Cited by 6 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Spacing of Palindromic Half Sites as a Determinant of Selective STAT (Signal Transducers and … - Full text - MIT Libraries
HM Seidel, LH Milocco, P Lamb, JE Darnell Jr, RB … - Proceedings of the National Academy of Sciences - pnas.org
... Nakajima, and T. Hirano Tissue-Specific Autoregulation of the stat3 Gene and ... Factor
Stimulates Phosphorylation and Activation of the Sp1 Transcription Factor ...
Cited by 102 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2 - Full text - MIT Libraries
A Martino, JH Holmes, JD Lord, JJ Moon, BH Nelson - J Immunol, 2001 - jimmunol.org
... Stat3 and Stat5 participation in the Sp1-DNA complex was detected by supershifting
Ab EMSA reactions, but the contributions of these factors to transcriptional ...
Cited by 33 - Web Search - jimmunol.org - jimmunol.org - jimmunol.org

Linkage between STAT regulation and Epstein-Barr virus gene expression in tumors - Full text - MIT Libraries
H Chen, JM Lee, Y Zong, M Borowitz, MH Ng, RF … - J Virol, 2001 - jvi.asm.org
... Johnson. 1998. Interleukin-6-specific activation of the C/EBPdelta gene in
hepatocytes is mediated by Stat3 and Sp1. Mol. Cell. Biol. ...
Cited by 22 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Angiogenic signal triggered by ischemic stress induces myocardial repair in rat during chronic … - Full text - MIT Libraries
S Fukuda, S Kaga, H Sasaki, L Zhan, L Zhu, H Otani … - J Mol Cell Cardiol, 2004 - uphs.upenn.edu
... post LAD occlusion. Significant activation of Stat3, Sp1, AP-1, TFIID,
Pax-5, NFjB were observed in IPMI group. Where Sham: Control ...
Cited by 5 - View as HTML - Web Search - ncbi.nlm.nih.gov

A ß-galactosidase Hybrid Protein Targeted to Nuclei as a Marker for Developmental Studies - Full text - MIT Libraries
C Bonnerot, D Rocancourt, P Briand, G Grimber, JF … - Am J Physiol Gastrointest Liver Physiol, 2003 - pnas.org
... Home page CA Cantwell, E. Sterneck, and PF Johnson Interleukin-6-Specific Activation
of the C/EBPdelta Gene in Hepatocytes Is Mediated by Stat3 and Sp1 Mol. ...
Cited by 74 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - csa.com

IMPAIRED INDUCTION OF IL-10 EXPRESSION IN THE LUNG FOLLOWING HEMORRHAGIC SHOCK.
RG Khadaroo, J Fan, KA Powers, B Fann, A Kapus, OD … - Shock, 2004 - shockjournal.com
... Effect of shock/resuscitation on STAT3 and Sp1/Sp3 nuclear translocation
TOP. Transcription factors STAT3 and Sp1/Sp3 have been shown ...
Cited by 1 - Web Search - shockjournal.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

C/EBPdIsa Downstream Mediatorof IL-6 Induced Growth Inhibitionof Prostate Cancer Cells
DC Sanford, JW DeWille, T … - The Prostate, 2004 - doi.wiley.com
... A third À393 bp promoter mutant construct was created which contained both
the STAT3 and Sp1 (double mutant) mutated binding sites. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Different mechanisms for leukemia inhibitory factor-dependent activation of two proopiomelanocortin … - Full text - MIT Libraries
V Mynard, L Guignat, J Devin-Leclerc, X Bertagna, … - Endocrinology, 2002 - endo.endojournals.org
... Free Full Text]; Cantwell CA, Sterneck E, Johnson PF 1998 Interleukin-6-specific
activation of the C/EBP gene in hepatocytes is mediated by Stat3 and Sp1. ...
Cited by 6 - Web Search - endo.endojournals.org - ncbi.nlm.nih.gov

Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in … - Full text - MIT Libraries
S Loeffler, B Fayard, J Weis, J Weissenberger - Int J Cancer, 2005 - ncbi.nlm.nih.gov
... endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter
activity in glioblastoma cells via direct interaction between STAT3 and Sp1. ...
Web Search

Signal Transducer and Activator of Transcription 3 {alpha} and Specificity Protein 1 Interact to … - Full text - MIT Libraries
XP Yang, K Irani, S Mattagajasingh, A DiPaula, F … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2005 - atvb.ahajournals.org
... HR Increases Phosphorylation of Stat3 on S727 and Results in Binding of Sp1 To study
the possible role of Stat3 and Sp1 cooperativity during HR, cultured HUVE ...
Web Search - atvbaha.org - atvb.ahajournals.org - ncbi.nlm.nih.gov - all 5 versions »

TransAM™
ST Factor, A Kits - activemotif.com
Page 1. I TransAM™ STAT3 Transcription Factor Assay Kits (version B2)
Catalog Nos. 45196 & 45696 ... 4 TransAM STAT3 . . . . . ...
View as HTML - Web Search - activemotif.com - funakoshi.co.jp - 61.195.166.45 - all 6 versions »

Activation of the Jak 3 pathway and myeloid differentiation
J Mangan, EP Reddy - Leukemia & Lymphoma, 2005 - dx.doi.org
... interferon-g [56], that STAT5 and Sp1 are responsible for IL-2-inducible regulation
of the cyclin D2 gene [57], and that STAT3 and Sp1 activate transcription ...
Web Search - taylorandfrancis.metapress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Aromatase expression in the human fetal osteoblastic cell line SV-HFO
M Watanabe, ER Simpson, N Pathirage, S Nakajin, CD … - Journal of Molecular Endocrinology - jme.endocrinology-journals.org
... Transfection of exogenous glucocorticoid receptor, STAT3 or Sp1 increased promoter
activity, indicating a potential role for these transcription factors in ...
Web Search - journals.endocrinology.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

CCAAT/Enhancer Binding Protein d (C/EBPd) Regulation and Expression in Human Mammary Epithelial … - Full text - MIT Libraries
GS Sivko, DC Sanford, LD Dearth, D Tang, JW … - Journal of Cellular Biochemistry, 2004 - doi.wiley.com
... Site- directed mutagenesis was used to create muta- tions in the STAT3 and Sp1 sites
within the À393 bp C/EBPd promoter/luciferase construct individually ...
Web Search

Angiogenic signal during cardiac repair
N Maulik - Molecular and Cellular Biochemistry, 2004 - springerlink.com
... Significant activation of Stat3, Sp1, AP-1, TFIID, Pax-5, NFκB were observed in
IPMI group; (A) CMI: non-preconditioned followed by LAD occlusion; (B) IPMI ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mechanisms associated with IL-6–induced up-regulation of Jak3 and its role in monocytic … - Full text - MIT Libraries
JK Mangan, SG Rane, AD Kang, A Amanullah, BC Wong, … - Blood, 2004 - bloodjournal.org
... 30K): [in this window] [in a new window], Figure 7. Cotransfection of Stat3 enhances
Jak3 promoter activity in M1 cells, and Sp1 and Stat3 proteins present in ...
Cited by 3 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Sp3 is involved in the regulation of SOCS3 gene-expression
C Ehlting, D Haeussinger, JG Bode - biochemj.org
... incubation with a STAT3- or a Sp1-specific antibody, indicating that neither
STAT3 nor Sp1 binds to the GC motif of the SOCS3 promoter. ...
Cited by 1 - View as HTML - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Composite regulatory elements: structure, function and classification.
S Receptor, HMG NF-kB, ETS SRF c-fos - Regulation - gene-regulation.com
... Cantwell,CA, Sterneck,E., and Johnson,PF (1998) Interleukin-6-specific activation
of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1. Mol. ...
Cached - Web Search - Get it from MIT Libraries

UNCORRECTED
N Maulik - kluweronline.com
Page 1. UNCORRECTED PR OOF TECHBOOKS Journal: MCBI MS Code: ND-04-6673
PIPS No: 5275104 DISK 22-6-2004 21:43 Pages: 11 Molecular ...
Web Search

Insulin Increases the Abundance of the Growth Hormone Receptor in Liver and Adipose Tissue of … - Full text - MIT Libraries
RP Rhoads, JW Kim, BJ Leury, LH Baumgard, N … - J Nutr, 2004 - nutrition.org
... 20). Primary antibodies were diluted in blocking solution (GHR and HNF4,
1:1000; STAT5, STAT3, Sp1 and JAK2, 1:2000). After incubation ...
Web Search - nutrition.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Forum Review
IP MediatedAngiogenic - ANTIOXIDANTS & REDOX SIGNALING, 2004 - dx.doi.org
... LAD occlusion. Significant activation of Stat3, SP1, AP-1, TFIID, Pax-5,
and NFkB were observed in the IPMI group. Sham, control ...
Web Search - liebertonline.com - liebertonline.com

IFN-alpha induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3 - Full text - MIT Libraries
L Ziegler-Heitbrock, M Lotzerich, A Schaefer, T … - J. Immunol, 2003 - jimmunol.org
... Rather, there is a complete dependence of the IRF action on Stat3. ... for the R(A) and
R(B) elements within the human RANTES promoter, which bind Sp1 and NK- B (28 ...
Cited by 10 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Cooperation between STAT3 and c-jun suppresses Fas transcription - Full text - MIT Libraries
VN Ivanov, A Bhoumik, M Krasilnikov, R Raz, LB … - Mol. Cell, 2001 - medschool.mc.vanderbilt.edu
... Stat3 / as well as c-Jun / cells exhibited in- creased Fas cell surface expression
and higher sensi- Similarly, the association of Stat1 with SP1 (Look et al ...
Cited by 51 - View as HTML - Web Search - ingentaconnect.com - all 5 versions »

Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus … - Full text - MIT Libraries
G Waris, A Siddiqui - J Virol, 2002 - jvi.asm.org
... 1998. Interleukin-6-specific activation of the C/EBP gene in hepatocyte is
mediated by Stat3 and Sp1. Mol. Cell. Biol. 18:2108-2117. ...
Cited by 8 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1 - Full text - MIT Libraries
K Su, X Yang, MD Roos, AJ Paterson, JE Kudlow - Biochem. J, 2000 - biochemj.org
... by Western-blot analysis using anti-Sp1 antibody (A, D and G). The membranes from
(A), (D) and (G) were stripped and reprobed with an anti-Stat3 antibody as a ...
Cited by 11 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Functional differences between STAT3 and STAT3 - Full text - MIT Libraries
TS Schaefer, LK Sanders, OK Park, D Nathans - Mol. Cell. Biol, 1997 - mcb.asm.org
... Examples of such cooperativity are those between Stat3 and Jun (24), between Stat1
and Sp1 (17), and between Stat5 and the glu- cocorticoid receptor (27). ...
Cited by 6 - Web Search

Induction of Human NF-IL6 {beta} by Epidermal Growth Factor Is Mediated through the p38 Signaling …
JM Wang, JT Tseng, WC Chang - molbiolcell.org
... 2000 ). STAT3 and Sp1 mediated the IL-6–induced mouse C/EBP gene expression
in hepatoma cells (Cantwell et al., 1998 ). STAT3 ...
Web Search - molbiolcell.org

A Member of the C/EBP Family, NF-IL6ss, Forms a Heterodimer and Transcriptionally Synergizes with NF … - Full text - MIT Libraries
S Kinoshita, S Akira, T Kishimoto - Proceedings of the National Academy of Sciences - pnas.org
... Home page CA Cantwell, E. Sterneck, and PF Johnson Interleukin-6-Specific Activation
of the C/EBPdelta Gene in Hepatocytes Is Mediated by Stat3 and Sp1 Mol. ...
Cited by 90 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Functional Analysis of–571 IL-10 Promoter Polymorphism Reveals a Repressor Element Controlled by … - Full text - MIT Libraries
JW Steinke, E Barekzi, J Hagman, L Borish - The Journal of Immunology, 2004 - jimmunol.org
... Proteins were cross-linked to the DNA with formaldehyde, and Abs directed against
Sp1, Sp3, or Stat3 (Ab control) were added to precipitate any protein-DNA ...
Cited by 1 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

E€ ect of dietary zinc deficiency on brain metallothionein-I and-III mRNA levels during stress and …
M Giralt, A Molinero, J Carrasco, J Hidalgo - Neurochemistry International, 2000 - tdx.cbuc.es
... In particular, it is thought that STAT3 plays a central role in the response to
IL-6 [4–6]. STAT3 binding to specific sequences in the promoter regions of ...
Cited by 5 - Web Search - tdx.cesca.es - ingentaconnect.com - all 6 versions »

ACTIVATION OF STAT3 BY ONCOGENIC RET/PTC TYROSINE KINASE: ROLES IN SPECIFIC GENE REGULATION AND …
JH Hwang, DW Kim, JM Suh, H Kim, JH Song, M Shong - mend.endojournals.org
- 1 - ACTIVATION OF STAT3 BY ONCOGENIC RET/PTC TYROSINE KINASE: ROLES IN SPECIFIC
GENE REGULATION AND CELLULAR ... Running title: Activation of STAT3 by RET/PTC ...
Web Search - mend.endojournals.org

Mpl ligand enhances the transcription of the cyclin D3 gene: a potential role for Sp1 transcription … - Full text - MIT Libraries
Z Wang, Y Zhang, J Lu, S Sun, K Ravid - Blood, 1999 - bloodjournal.org
... two distinct signaling pathways: a specific Tyk2-JAK2/STAT1-STAT3-STAT5 signaling ...
17-19 Our EMSA experiments suggested that dephosphorylation of Sp1 by PP1 ...
Cited by 17 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Regulation of IL-6 signaling by p53: STAT3-and STAT5-masking in p53-Val135-containing human hepatoma … - Full text - MIT Libraries
RJ Rayanade, MI Ndubuisi, JD Etlinger, PB Sehgal - J. Immunol, 1998 - jimmunol.org
... loss of STAT3 and STAT5 immunofluorescence was selective in that it was not observed
for STAT1; STAT4; STAT6; C/EBP- , -ß, or - ; or Sp1 transcription factors ...
Cited by 16 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Stat3 and Tumor Cell Proliferation
N Schick - unibas.ch
Page 1. Stat3 and Tumor Cell Proliferation Inauguraldissertation zur Erlangung der
Würde eines Doktors der Philosophie ... 42 4.2 Stat2 42 4.3 Stat3 42 3 Page 5. ...
View as HTML - Web Search - pages.unibas.ch - unibas.ch - pages.unibas.ch

Stat 1 depends on transcriptional synergy with Sp 1. - Full text - MIT Libraries
DC Look, MR Pelletier, RM Tidwell, WT Roswit, MJ … - J Biol Chem, 1995 - jbc.org
... Additional immunoblotting indicated that hTBECs also contain Stat2, -3, -5, and
-6; however, only Stat3 appeared to directly interact with Sp1 (data not shown ...
Cited by 117 - Web Search - jbc.org - ncbi.nlm.nih.gov

CCAAT/enhancer binding protein δ(C/EBPδ) regulation and expression in human mammary epithelial … - Full text - MIT Libraries
GS Sivko, DC Sanford, LD Dearth, D Tang, JW … - Journal of Cellular Biochemistry, 2004 - ncbi.nlm.nih.gov
... STAT3 construct (STAT3delta) reduces C/EBPdelta promoter activity in response to
growth arrest conditions. The human C/EBPdelta promoter also contains an Sp1 ...
Cited by 3 - Web Search

Characterization of new mutations in the coding sequence and 5′-untranslated region of the human … - Full text - MIT Libraries
D Chevalier, C Cauffiez, C Bernard, JM Lo-Guidice, … - Hum. Genet, 2001 - springerlink.com
... 11:1–3 Cantwell CA, Sterneck E, Johnson PF (1998) Interleukin-6-spe- cific activation
of the C/EBPdelta gene in hepatocytes is medi- ated by Stat3 and Sp1. ...
Cited by 16 - Web Search - ncbi.nlm.nih.gov

Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin … - Full text - MIT Libraries
M Harris, C Aschkenasi, CF Elias, A Chandrankunnel … - J Clin Invest, 2001 - jci.org
... Interleukin-6-specific activation of the C/EBP gene in hepatocytes is
mediated by STAT3 and SP1. Mol. Cell. Biol. 18:2108-2117. ...
Cited by 53 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Requirement of STAT3 activation for differentiation of mucosal stratified squamous epithelium - Full text - MIT Libraries
R WU, S SUN, BM STEINBERG - Mol. Med, 2003 - molmed.org
... Sp1 and AP2 transcription factors also were shown to be important for the up-regulation
of keratin genes during dif- ferentiation (44,45). Potential STAT3 ...
Cited by 2 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Inhibitory effect of genistein on activation of STAT3 induced by brain ischemia/reperfusion in rat …
LI Hong-Chun, Z Guang-Yi - chinaphar.com
... Lane 2 is non-competitive reactions with nonrelated probe SP1. Lane 3 indicates
supershift assay with anti-STAT3 antibody, and lane 4 specifies competitive ...
View as HTML - Web Search - chinaphar.com

A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT 3 - Full text - MIT Libraries
K Nakayama, KW Kim, A Miyajima - The EMBO Journal, 2002 - embojournal.npgjournals.com
... Cantwell,CA, Sterneck,E. and Johnson,PF (1998) Interleukin-6-specific activation
of the C/EBP gene in hepatocytes is mediated by Stat3 and Sp1. Mol. Cell. ...
Cited by 5 - Web Search - nature.com - emboj.org - ncbi.nlm.nih.gov - all 7 versions »

Characterization of phosphopeptide motifs specific for the src homology 2 (SH2) domains of signal … - Full text - MIT Libraries
M Wiederkehr-Adam, P Ernst, K Mueller, E Bieck, FO … - J. Biol. Chem, 2004 - jbc.org
... transcription 1 (STAT1) and STAT3 Michèle Wiederkehr-Adam*, Philipp Ernst*, Kurt
Müller†, Elke Bieck*, Frank O. ... Phosphopeptide binding of STAT1 and STAT3 ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov

Aromatase P 450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of … - Full text - MIT Libraries
Y Zhao, JE Nichols, SE Bulun, CR Mendelson, ER … - J Biol Chem, 1995 - ncbi.nlm.nih.gov
... STAT3 but not STAT1 was also phosphorylated and bound to the GAS element ... a Jak/STAT
signaling mechanism acting together with glucocorticoids and Sp1 appears to ...
Cited by 116 - Web Search

The STAT3 DNA-Binding Domain Mediates Interaction with NF-{kappa} B p65 and Inducible Nitric Oxide … - Full text - MIT Libraries
Z Yu, BC Kone - J Am Soc Nephrol, 2004 - jasn.org
... binding domain, outside the region identified in the present report, of STAT3 were
found ... a wide variety of factors, including p48/IRF9, these SMAD, Sp1, USF-1 ...
Cited by 2 - Web Search - jasn.org - jasn.org - ncbi.nlm.nih.gov - all 5 versions »