TFII-I enhances activation of the c-fos promoter through interactions with upstream elements - Full text - MIT Libraries
DW Kim, V Cheriyath, AL Roy, BH Cochran - Mol. Cell. Biol, 1998 - mcb.asm.org
... factors. Moreover, TFII-I can form in vivo protein-protein complexes with
the c-fos upstream activators SRF, STAT1, and STAT3. These ...
Cited by 28 - Web Search - pubmedcentral.nih.gov - cochranlab.org - ncbi.nlm.nih.gov - all 6 versions »

Simultaneous tyrosine and serine phosphorylation of stat3 transcription factor is involved in rho a … - Full text - MIT Libraries
S Aznar, PF Valeron, SV del Rincon, LF Perez, R … - Mol. Biol. Cell, 2001 - molbiolcell.org
... RhoA QL-induced SIE transcription. (C) Dominant negative Stat3 do not inhibit
SRF activation by RhoA. The same amounts of RhoAQL ...
Cited by 9 - Web Search - molbiolcell.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Contribution of Both STAT and SRF/TCF to c-fos Promoter Activation by Granulocyte-Macrophage Colony- … - Full text - MIT Libraries
S du Qutbec - Blood, 1996 - bloodjournal.org
... activation in response to GM-CSF, the SRF binding site (SRE) and/or the STAT binding ...
indi- cate that GM-CSF induced DNA binding of both STAT1 and STAT3 in NIH ...
Cited by 28 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes - Full text - MIT Libraries
K Kunisada, E Tone, Y Fujio, H Matsui, K Yamauchi- … - Circulation, 1998 - circ.ahajournals.org
... M, Inoue M, Wei S, Takeda K, Matsumoto M, Kishimoto T, Akira S. STAT3 activation
is a ... S, Liu L, Krystal G, Hoang T. Contribution of both STAT and SRF/TCF to c ...
Cited by 77 - Web Search - circ.ahajournals.org - ncbi.nlm.nih.gov

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional … - Full text - MIT Libraries
J Turkson, T Bowman, J Adnane, Y Zhang, JY Djeu, M … - Mol Cell Biol, 1999 - mcb.asm.org
... Requirement for Ras/Rac1-Mediated p38 and c-Jun N-Terminal Kinase Signaling in
Stat3 Transcriptional Activity Induced by the Src Oncoprotein. ...
Cited by 89 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary … - Full text - MIT Libraries
Y Aoki, GM Feldman, G Tosato - Blood, 2003 - bloodjournal.org
... Contribution of both STAT and SRF/TCF to c-fos promoter activation by granulocyte-
macrophage ... A central role for Stat3 in IL-6-induced regulation of growth and ...
Cited by 37 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno- … - Full text - MIT Libraries
C Bousquet, MC Zatelli, S Melmed - J. Clin. Invest, 2000 - jci.org
... contain STAT3 and 36 kDa CRE-like site binding protein(s). Oncogene. 12:547-554.[
Medline]; Rajotte, D. et al.1996. Contribution of both STAT and SRF/TCF to c ...
Cited by 26 - Web Search - jci.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Insulin activates Stat3 independently of p21ras-ERK and PI-3K signal transduction - Full text - MIT Libraries
L Koenderman, JL Bos, W Kruijer - Oncogene, 1997 - nature.com
Insulin activates Stat3 independently of p21ras-ERK and PI-3K signal ... These ®ndings
raise the possibility that Stat3 also contributes to oncogenesis by Src. ...
Web Search

Gfi-1 und Pias3 als Antagonisten bei der Stat3 Signaltransduktion
E des Doktorgrades, B Roedel - miless.uni-essen.de
... 68 über verstärkte Stat3 Aktivierung 3.2.3 Gfi-1 und Stat3 als Onkogene 70 4.
Zusammenfassung 72 5. Material und Methoden ... S6K Sos p38 SRF Elk Rsk ERK MEK3/6 ...
View as HTML - Web Search - deposit.ddb.de

Ras regulation and function in lymphocytes - Full text - MIT Libraries
E Genot, DA Cantrell - Curr Opin Immunol, 2000 - iecb-polytechnique.u-bordeaux.fr
... 3-kinase PI(4,5)P 2 phosphatidylinositol (4,5) biphosphate PLC phospholipase C SH
src-homology SRF serum response factor STAT3 signal transducer and activator ...
Cited by 53 - View as HTML - Web Search - ncbi.nlm.nih.gov

Composite regulatory elements: structure, function and classification.
S Receptor, HMG NF-kB, ETS SRF c-fos - Regulation - gene-regulation.com
... ETS, SRF, c-fos, human ... CA, Sterneck,E., and Johnson,PF (1998) Interleukin-6-specific
activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1 ...
Cached - Web Search - Get it from MIT Libraries

Regulation of expression of the rat serine protease inhibitor 2.3 gene by glucocorticoids and …
AE SIMAR-BLANCHET, P Conception, L MERCIER, A LE … - Eur. J. Biochem, 1996 - blackwell-synergy.com
... Binding specificity C/EBP (u, p, 6) STAT3 HNFl NFKB SRF, STAT C/EBP, Stat 5
5'-gtgTCCAGTGATGTAATCAGGC AGGTCACTACATTAGTCCGgtg-5' Rat hemopexin ...
Cited by 5 - Web Search - ingentaconnect.com - ejbiochem.org - content.febsjournal.org - all 5 versions » - Get it from MIT Libraries

The STAT 3-independent Signaling Pathway by Glycoprotein 130 in Hepatic Cells - Full text - MIT Libraries
C Lai, J Ripperger, Y Wang, H Kim, RB Hawley, H … - J Biol Chem, 1999 - jbc.org
... MAPK is known to phosphorylate and modulate the activities of transcription factors
such as STAT3, C/EBP , CREB, SRF, AP-1, ATF-2, and Elk-1 (35, 53, 54). ...
Cited by 16 - Web Search - jbc.org - ncbi.nlm.nih.gov

SOCS-3 Induces Myoblast Differentiation
EE Spangenburg - Journal of Biological Chemistry - jbc.org
... like growth factor; SOCS, suppressor of cytokine signaling; SRF, serum response
factor; NFAT, nuclear factor of activated T cell; STAT3, signal transducer and ...
Web Search - jbc.org - Get it from MIT Libraries

The endogenous interferon system in anal squamous epithelial lesions with different grades from HIV- … - Full text - MIT Libraries
I Arany, M Muldrow, SK Tyring - International Journal of STD & AIDS, 2001 - ingentaconnect.com
... STAT3 is required for the gp130-mediated full activation of the c-myc genes. ...
Contribution of both STAT and SRF/TCF to c-fos promoter activation by granulocyte ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Functional Interaction of STAT 3 Transcription Factor with the Coactivator NcoA/SRC 1 a - Full text - MIT Libraries
S Giraud, F Bienvenu, S Avril, H Gascan, DM Heery, … - J Biol Chem, 2002 - jbc.org
... NcoA/SRC1 Potentiates STAT3 Transcriptional Activity-- Recent results have shown
that NcoA/SRC1 can potentiate the transcriptional activity of AP-1, SRF, NF- B ...
Cited by 34 - Web Search - med.univ-angers.fr - qb.fcen.uba.ar - ncbi.nlm.nih.gov - all 6 versions »

Lipopolysaccharide Stimulates p 38-dependent Induction of Antiviral Genes in Neutrophils … - Full text - MIT Libraries
KC Malcolm, GS Worthen - J Biol Chem, 2003 - jbc.org
... transcription factors, including activating transcription factor-2, SRF accessory
protein-1 ... Anti-STAT1 and -STAT3 were obtained from Transduction Laboratories ...
Cited by 4 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional Regulatory Networks Activated by PI3K and ERK Trans-duced Growth Signals in Human …
PM Haverty, Z Weng, U Hansen - zlab.bu.edu
... this network on the basis of the promoter analyses are CRE-BP1, CREB, E4F1, and
STAT3. ... analyses are OCT-x, CREB, Freac-3, Freac-4, Roaz, and HFH-3, and SRF. ...
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Characterization and gene structure of a novel retinoblastoma-protein-associated protein similar to … - Full text - MIT Libraries
YAN Xiumin, X ZHAO, Q Min, N GUO, X GONG, ZHU … - Biochem. J, 2000 - biochemj.org
... 2000 Biochemical Society Page 2. 750 X. Yan and others [10], SRF and Phox1
[11], and STAT1 and STAT3 [14]. In addition, TFII-I ...
Cited by 18 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

STAT proteins and transcriptional responses to extracellular signals - Full text - MIT Libraries
CM Horvath - Trends Biochem Sci, 2000 - chosun.ac.kr
... directly to STAT3 and STAT1 (Fig. 3e). TFII-I also binds to the serum-response factor
(SRF) and DNA, potentially forming a scaffold for en- hancer assembly. ...
Cited by 93 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Opposing Roles of Elk-1 and Its Brain-specific Isoform, Short Elk-1, in Nerve Growth Factor-induced … - Full text - MIT Libraries
P Vanhoutte, JL Nissen, B Brugg, BD Gaspera, MJ … - J Biol Chem, 2001 - jbc.org
... the B domain) that mediates protein-protein interaction with SRF (9-11 ... 1 (Santa Cruz
Biotechnology), Zif268 (Santa Cruz Biotechnology), and STAT3 (New England ...
Cited by 16 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

A novel transcriptional regulatory region within the core promoter of the hepatocyte growth factor … - Full text - MIT Libraries
JG Jiang, R Zarnegar - Mol Cell Biol, 1997 - mcb.asm.org
... 3 ; Stat3, 5 -GATCCTTCTGGAATT CCTAGATC-3 ; YY1, 5 -CGCTCCGCGGCCATCTTGGCGGCTGGT-3 ;
and antibodies against C/EBP , C/EBP , C/EBP , SRF, Elk-1, Oct-1, and Stat3. ...
Cited by 20 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

ATL and HTLV-I: In vivo cell growth of ATL cells
T Uchiyama - Journal of Clinical Immunology, 1996 - springerlink.com
... through interaction with transcription factors such as NFkB, SRF, and CREB ... the
activation of signal transducing molecules including JAK1, JAK3, STAT3, and STAT5 ...
Cited by 6 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

On the Power of Profiles for Transcription Factor Binding Site Detection
S Rahmann, T Mueller, M Vingron - Statistical Applications in Genetics and Molecular Biology, 2003 - genereg.molgen.mpg.de
Page 1. On the Power of Profiles for Transcription Factor Binding Site Detection
Sven Rahmann 1,2,∗ , Tobias Muller 1,3 , and Martin Vingron 1 ...
Cited by 11 - View as HTML - Web Search - molgen.mpg.de - gi.cebitec.uni-bielefeld.de

Departments of Biochemistry and Molecular Biophysics, and Medicine Washinaton Universitv School of …
AM Gronowski, Z Zhong, Z Wen, MJ Thomas, JE … - mend.endojournals.org
... Stat3 Ann M. Gronowski*, Zhong Zhong, Zilong Wen, ... Activated Stat3 interacts
with the naturally occurring cs&inducible element of ...
Web Search

Signaling specificity - Full text - MIT Libraries
PBO Tan, SK Kim - protein. Science - ww2.mcgill.ca
... (e) Distinct signals might converge on and control the function of protein complexes,
such as the activity of the SRF–ELK-1 transcription factor complex. ...
Cited by 66 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

IL-12 selectively regulates STAT4 via phosphatidylinositol 3-kinase and Ras-independent signal …
V Athie-M, H Flotow, KL Hilyard, DA Cantrell - differentiation - doi.wiley.com
... The phosphorylation of STAT3 § on serine 727 can be regulated via the Ras/mitogen-
activated protein kinase (MAPK) pathway, notably Erk1,2 [14, 15]. ...
Cited by 9 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Repression of Stat 3 activity by activation of mitogen-activated protein kinase(MAPK) - Full text - MIT Libraries
N Jain, T Zhang, SL Fong, CP Lim, X Cao - Oncogene, 1998 - nature.com
... These data demonstrate that ERK2 activated by MEK1 negatively regulates Stat3
transcriptional activity ... The active TCF binds to SRF and SRE to form a ternary ...
Cited by 73 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and … - Full text - MIT Libraries
D De Cesare, S Jacquot, A Hanauer, P Sassone-Corsi - Biochemistry, 1998 - dx.doi.org
... the Elk-1 B Box Inhibits RhoA-Actin Signaling to SRF and Potentiates ... Kedinger The
Ribosomal S6 Kinases, cAMP-responsive Element-binding, and STAT3 Proteins Are ...
Cited by 110 - Web Search - pnas.org - pubmedcentral.nih.gov - adsabs.harvard.edu - all 8 versions »

Mechanism of plasminogen activator inhibitor-1 regulation by oncostatin M and interleukin-1 in human … - Full text - MIT Libraries
A Kasza, DL Kiss, S Gopalan, W Xu, RE Rydel, A Koj … - Journal of Neurochemistry, 2002 - blackwell-synergy.com
... but can activate c-fos expression via serum response factor (SRF) (Montaner et al ...
B in astrocytes whereas OSM activated the binding of STAT1 and STAT3 (but not ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Steroid Receptor Coactivator SRC-1 links the steroid and interferon γ response pathways - Full text - MIT Libraries
E Tzortzakaki, C Spilianakis, E Zika, A Kretsovali … - Mol Endocrinol, 2003 - mend.endojournals.org
... mediated transcription ie NFκB (30, 31), SRF (32), AP1 (33), STAT6 (34), STAT3
(35), has lately expanded their role in gene regulation. ...
Cited by 4 - Web Search - imbb.forth.gr - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Pleiotropic effects of cytokines on acute myocardial infarction: G-CSF as a novel therapy for acute …
H Takano, M Ohtsuka, H Akazawa, H Toko, M Harada, … - Curr Pharm Design, 2003 - ingentaconnect.com
... upregulated by G-CSF, but not GM- CSF, through activation of JAK2-STAT3 pathway ... They
identified that serum response factor (SRF) and the ETS protein Fli-1 bind ...
Cited by 12 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Statistical Applications in Genetics and Molecular Biology
FBS Detection - bepress.com
Page 1. Statistical Applications in Genetics and Molecular Biology Volume 2, Issue
1 2003 Article 7 On the Power of Profiles for Transcription ...
Web Search

MBC in Press, published on October 16, 2002 as 10.1091/mbc. E02-08-0454
SA Benitah, PF Valeron, H Rui, JC Lacal - molbiolcell.org
... In our particular system, we have observed that Stat5a modulates the expression
of vimentin and E-cadherin. Whether SRF and ... Although Stat3 has been ...
Web Search

A multifunctional DNA-binding protein that promotes the formation of serum response factor/ … - Full text - MIT Libraries
DA Grueneberg, RW Henry, A Brauer, CD Novina, V … - Genes Dev, 1997 - genesdev.org
... Taken together, these results suggest that p120 interacts directly with SRF and
Phox1 ... c-sis-inducible factor), which is composed of Stat1 and Stat3 (Hayes et al ...
Cited by 69 - Web Search - genesdev.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

GEArray Q series Mouse cAMP/Ca2+ PathwayFinder Gene Array: AR-SAMM-028
FG Grouping - eurogentec.com
... Fosb, Hspa4 (hsp70), Junb, Nr4a2 (Nur77), Scg2 (secretogranin II), Srf, Thbs1
(TSP-1 ... Fos, Jund1, Maf2-Ests, Nr4a2 (Nur77), Per1, Pit1, Pou2af1 (OCA- B), Stat3 ...
View as HTML - Web Search - eurogentec.be

GEArray Q Series Human G-Proteins & Signaling Molecules Gene Array: AR-SAHS-047
FG Grouping - eurogentec.be
... GRB2, MAP2K1 (MEK1), MAP2K2, MAPK1, MAPK3, MAPK7 (ERK5), RAF1, RAP1A, SHC1, SOS1,
STAT3. ... PRKCB1, PRKCE, PRKCG, PRKCM, PTK2 (FAK), PXN, RAF1, ROCK1, SRF, VAV1. ...
View as HTML - Web Search - eurogentec.com

GEArray Q series Human cAMP/Ca2+ PathwayFinder Gene Array: AR-SAHS-028
FG Grouping - eurogentec.com
... Hsp70), JUNB, NR4A2 (Nur77), S100A6 (Calcyclin), SCG2 (secretogranin II), SRF, THBS1
(TSP ... JUND, MAF, NR4A2 (Nur77), PER1, POU1F1 (Pit-1), POU2AF1 (OCA-B), STAT3 ...
View as HTML - Web Search - eurogentec.be

TFII-I Regulates Induction of Chromosomally Integrated Human Immunodeficiency Virus Type 1 Long … - Full text - MIT Libraries
J Chen, T Malcolm, MC Estable, RG Roeder, I … - J Virol, 2005 - jvi.asm.org
... bound to upstream enhancer elements in association with a variety of transcription
factors, including USF1, SRF, Phox1, NF- B, Myc, STAT1, STAT3, and YY1 (35). ...
Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Inhibition of Stat1-mediated gene activation by PIAS1 - Full text - MIT Libraries
B Liu, J Liao, X Rao, SA Kushner, CD Chung, DD … - Cell, 1998 - dx.doi.org
... transcriptional activity by protein inhibitor of activated STAT3 (PIAS3) PNAS ... a Potent
Transcriptional Coactivator for Serum Response Factor (SRF), Is Required ...
Cited by 182 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Interleukin-10 Suppresses Tissue Factor Expression in Lipopolysaccharide-Stimulated Macrophages via … - Full text - MIT Libraries
M Kamimura, C Viedt, A Dalpke, ME Rosenfeld, N … - Circulation Research, 2005 - circresaha.org
... phosphorylation of Elk-1, although the mild induction of SRF in response to ... for signal
transducer and activator of transcription (STAT) factors, such as STAT3. ...
Cached - Web Search - circres.ahajournals.org - circresaha.org - circres.ahajournals.org

Growth hormone protects against radiotherapy induced cell death - Full text - MIT Libraries
O Madrid, S Varea, I Sanchez-Perez, L Gomez-Garcı … - Eur J Endocrinol, 2002 - eje.org
... Some of these pathways, particularly those driven by JAK2 and MAPK, can activate
transcription mediated by STAT3 and STAT5 as well as SRF and c-fos (47, 30, 48 ...
Cited by 1 - View as HTML - Web Search - eje.org - eje-online.org - ncbi.nlm.nih.gov

Expression and function of the protein tyrosine phosphatase SHP-1 in oligodendrocytes - Full text - MIT Libraries
PT Massa, S Saha, C Wu, KW Jarosinski - Glia, 2000 - doi.wiley.com
... Specific inhibition of Stat3 signal transduction by PIAS3. ... The Rho family GTPases
RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. ...
Cited by 10 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth … - Full text - MIT Libraries
DW Leaman, S Pisharody, TW Flickinger, MA Commane, … - Mol Cell Biol, 1996 - mcb.asm.org
... Together, the results suggest that STAT1 and STAT3 may each interact directly with
the EGFR. ... The SRF accessory protein Elk-1 contains a growth factor-regulated ...
Cited by 105 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Isolation of a Pluripotent Cell Line from Early Mouse Embryos Cultured in Medium Conditioned by … - Full text - MIT Libraries
GR Martin - Development, 2005 - pnas.org
... Home page, Stem Cells Home page T. Sumi, Y. Fujimoto, N. Nakatsuji, and H. Suemori
STAT3 Is Dispensable for Maintenance of Self-Renewal in Nonhuman Primate ...
Cited by 545 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... JAK and STAT Proteins: JAK1, JAK2, JAK3, STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B ...
MMP3, MST1, NPPB, NOS3, OAS1, ORM1, PIN1, SAA1, SFN, SLC2A4, SRF, TERT, YWHAZ ...
View as HTML - Web Search - eurogentec.be

STAT5a Activation Mediates the Epithelial to Mesenchymal Transition Induced by Oncogenic RhoA. - Full text - MIT Libraries
SA Benitah, PF Valeron, H Rui, JC Lacal - Mol Biol Cell, 2003 - molbiolcell.org
... have been described with respect to the activation of the SRF and its ... reported that
oncogenic RhoA and Cdc42 activate the transcription factor Stat3 in human ...
Cited by 5 - Web Search - pubmedcentral.gov - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »

Role of the tyrosine kinase JAK 2 in signal transduction by growth hormone - Full text - MIT Libraries
C Carter-Su, L Rui, J Herrington - Pediatric Nephrology, 2000 - springerlink.com
... Migrations of Stat1, Stat3 and Stat5 are indi- cated [Reprinted with permission
from ... 1 and 3, and a serum response element (SRE), which binds SRF and ternary ...
Cited by 8 - Web Search - cmmg.biosci.wayne.edu - ncbi.nlm.nih.gov

Workshop J Signal Transduction and Gene Regulation
T Brdicka, N Brdickova, M Imrich, B Schraven, V … - ingentaconnect.com
Page 1. 1 Institute of Molecular Genetics, Academy of Sciences of the Czech
Republic, Prague, Czech Republic and 2 Institute of Immunology ...
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IDENTIFICATIuN OF GROWTH HORMONE RESPONSE SEQUENCE IN RAT IGFBP-
A Thesis, M Winnipeg - collectionscanada.ca
Page 1. IDENTIFICATIûN OF GROWTH HORMONE RESPONSE SEQUENCE IN RAT IGFBP-1
PROMOTER A Thesis Submitted to the fadty of Graduate studies ...
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