Transcriptional activity of TAL 1 in T cell acute lymphoblastic leukemia(T-ALL) requires RBTN 1 or-2 … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - J Biol Chem, 1997 - jbc.org
... differentiation (27-30). Furthermore, Osada et al. (24) demonstrated direct
binding of RBTN2 with TAL1 and GATA2. On the other hand ...
Cited by 18 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

protein GATAl - Full text - MIT Libraries
H OSADA, G GRUTZ, H AXELSON, A FORSTER, TH … - Proc. Natl. Acad. Sci. USA, 1995 - pnas.org
... like pro- teins GATAl (4-7) and GATA2 (8) and-later that the basic
helix-loop-helix (bHLH) protein TAL1/SC1 (9) are neces- sary for ...
Cited by 85 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

RBPj {kappa}-dependent Notch function regulates Gata2 and is essential for the formation of intra- … - Full text - MIT Libraries
A Robert-Moreno, L Espinosa, JL de la Pompa, A … - Development, 2005 - dx.doi.org
... the absence of hematopoietic progenitors, accompanied by the lack of expression
of the hematopoietic transcription factors Aml1/Runx1, Gata2 and Scl/Tal1. ...
Web Search - dev.biologists.org - dev.biologists.org - ncbi.nlm.nih.gov

THE LMO2 MASTER GENE; ITS ROLE AS A TRANSCRIPTION REGULATOR DETERMINING CELL FATE IN LEUKEMOGENESIS …
C TRANSLOCATIONS, D REGULATION - doi.wiley.com
... In this model, as differentiation proceeds, Gata2 of a Lmo2/Tal1/Gata2 complex,
in an early hematopoietic progenitor, is replaced by Gata1 in erythroid ...
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TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - Mol. Cell. Biol, 1998 - mcb.asm.org
... 5D), the TAL1-E47 heterodimer may act as a transcriptional coactivator for ... the
regulation of endothelin-1 gene expression in endothelial cells, GATA2 and AP1 ...
Cited by 39 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem … - Full text - MIT Libraries
S Gerecht-Nir, JE Dazard, M Golan-Mashiach, S … - Developmental Dynamics, 2005 - doi.wiley.com
... related receptors FLT1, FLT4, PDGFRB, TGF R2, and TGF R3, other markers such as
CD34, VCAM1, PECAM1, VE-CAD, and transcription factors TAL1, GATA2, and GATA3. ...
Cited by 2 - Web Search - weizmann.ac.il - weizmann.ac.il - ncbi.nlm.nih.gov

Hematopoietic Stem Cell Enrichment From the AGM Region of the Mouse Embryo
C Robin, E Dzierzak - Methods Mol Med, 2005 - biomed.humanapress.com
... CD34 + cells in the clusters express some transcriptional factors (SCL/Tal1,
GATA2 and 3, c-myb; refs. 29,46,48) and also many molecules ...
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A complex linkage in the developmental pathway of endothelial and hematopoietic cells
SI Nishikawa - Curr Opin Cell Biol, 2001 - cbi.pku.edu.cn
... The finding that tal1 (–/–) and lmo2 ... HPC and vascular remodelling Runt related
transcription factor 1 (Runx1), GATA-binding protein 2 (GATA2) and c-myb are ...
Cited by 19 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Functional Analysis of Human Hematopoietic Stem Cell Gene Expression Using Zebrafish - Full text - MIT Libraries
CE Eckfeldt, EM Mendenhall, CM Flynn, TF Wang, MA … - PLoS Biol, 2005 - medicine.plosjournals.org
... BMP signaling) and commitment (vascular endothelial growth factor signaling; flk1,
also known as kdr; lmo2; scl, also known as tal1; gata2; gata1) are ...
Cached - Web Search - plme.allenpress.com - biology.plosjournals.org - pubmedcentral.nih.gov

Studies of the Ribosomal Protein S19 in Erythropoiesis
H MATSSON - publications.uu.se
... The commitment of hematopoietic cells to undergo erythroid devel- opment is regulated
by several transcription factors including TAL1, LMO2 and GATA2 (4). ...
Web Search - diva-portal.org

Expression of alpha4-integrin defines the earliest precursor of hematopoietic cell lineage diverged … - Full text - MIT Libraries
M Ogawa, M Kizumoto, S Nishikawa, T Fujimoto, H … - Blood, 1999 - bloodjournal.org
... Different dilutions of cDNA prepared from sorted cells were subjected to PCR
amplification specific for Gata1, Gata2, Tal1, Lmo2, Myb, and Gapd transcripts. ...
Cited by 35 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Hematopoietic differentiation of human embryonic stem cells progresses through sequential … - Full text - MIT Libraries
ET Zambidis, B Peault, TS Park, F Bunz, CI Civin - Blood, 2005 - bloodjournal.org
... expression analysis of differentiating hEBs revealed that initiation of hematopoiesis
correlated with increased levels of SCL/TAL1, GATA1, GATA2, CD34, CD31 ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

The GATA-E box-GATA motif in the EKLF promoter is required for in vivo expression - Full text - MIT Libraries
KP Anderson, SC Crable, JB Lingrel - Blood, 2000 - bloodjournal.org
... cells that apparently contacts the DNA through the GATA1 and Tal1 proteins ... One
explanation for this apparent inconsistency is compensation by GATA2 because the ...
Cited by 8 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Supplementary Data ‘Stemness’: Transcriptional Profiling of Embryonic and Adult Stem Cells
M Ramalho-Santos, S Yoon, Y Matsuzaki, RC Mulligan … - intl.sciencemag.org
... While this subtractive approach did not detect numerous HSC markers (including
Notch1, Abcg2, Tie1, Tie2, Vla5, Flp, Tal1/Scl, Gata2, Mll, ...
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Analysis of the relationship between Scl transcription factor complex protein expression patterns …
AM Rice, KM Holtz, J Karp, S Rollins, AC … - Leuk Res, 2004 - ncbi.nlm.nih.gov
... Exogenous expression of the transcription factor Scl (Tal1) in WEHI-3B D+
myelomonocytic ... APL blasts, while the levels of expression of Rbtn1, GATA2, and GATA3 ...
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Oligo GEArray® Human Hematopoietic Stem Cells and Hematopoiesis Microarray
S Conditions - search.cosmobio.co.jp
... CBFB, CD80, CD86, CEBPE, CEBPG, EGR1, ETS1, ETV6, GATA1, GATA2, GFI1, HDAC4 ... NOTCH4,
PAX5, RBPSUH, RHOH, RUNX1, SCAND1, STAT1, STAT3, STAT4, TAL1, VAV1, WWP1 ...
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In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... 100 to 200 Tal1 - Tal1 - Tal1 - 47S, 47S 47S, CFI-USP CFI-USP ... 700 to 600 GATA1, GATAX,
CdxA SRY Mkx-2 GATA2, GATA1 GATA3 600 to 500 GATA1 Sp1 Mkx-2 ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells - Full text - MIT Libraries
H Ohta, A Sawada, JY Kim, S Tokimasa, S Nishiguchi … - J Exp Med, 2002 - jem.org
... gp130, Epo receptor, G-CSF receptor, GM-CSF receptor, c-erbA , c-Mpl, c-jun, c-fos,
c-myc, c-myb, tal1/SCL, AML1, GATA1, GATA2, and PU.1. Expression of none of ...
Cited by 29 - Web Search - intl.jem.org - ncbi.nlm.nih.gov

transcripts including those of the PU. 1 gene - Full text - MIT Libraries
H Okada, T Watanabe, M Niki, H Takano, N Chiba, N … - Oncogene, 1998 - nature.com
... AML1 PEBP2 b/CBF b PEBP2 aA GATA1 GATA2 Ikaros Scl/tal1 PU.1 NFE2 c-Myb ¯k-1
¯k-2/¯t-3 ¯t-1 SCF c-Kit Epo Epo receptor M-CSF M-CSF receptor G-CSF G-CSF ...
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Scl is required for dorsal aorta as well as blood formation in zebrafish embryos - Full text - MIT Libraries
LJ Patterson, M Gering, R Patient - Blood, 2005 - bloodjournal.org
... One gene, expressed in hemangioblast populations, is scl/tal1, hereafter referred
to as scl ... E, arrows) and was lost by 10 somites (14 hpf) (E). Gata2, fli1, and ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Tal 1/SCL Binding to Pericentromeric DNA Represses Transcription - Full text - MIT Libraries
J Wen, S Huang, SD Pack, X Yu, SJ Brandt, CT … - J Biol Chem, 2005 - jbc.org
... preferred Tal1/SCL sequence (T1, lane 8). Binding to the GATA motif was reduced
by antibodies specific for GATA-1 ( -GATA1, lane 10) and GATA-2 ( -GATA2, lane ...
Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of … - Full text - MIT Libraries
L Edvardsson, J Dykes, ML Olsson, T Olofsson - British Journal of Haematology, 2004 - ask.lub.lu.se
... Hs 00372339_g1 EPOR EpoR Hs 00181092_m1 GATA1 GATA-1 Hs 00231112_m1 GATA2 GATA-2 ...
PRTN3 PR3 (proteinase 3) Hs 00160521_m1 SPI1 PU.1 Hs 00231368_m1 TAL1 SCL/Tal1 ...
Cited by 1 - View as HTML - Web Search - ncbi.nlm.nih.gov

A nonsense mutation in zebrafish gata 1 causes the bloodless phenotype in vlad tepes - Full text - MIT Libraries
SE Lyons, ND Lawson, L Lei, PE Bennett, BM … - Proceedings of the National Academy of Sciences, 2002 - pnas.org
... However, up-regulation of gata2 within a subset of cells such as the proerythroblasts
would ... Y. Yamada, TH Rabbitts, and RK Patient Lmo2 and Scl/Tal1 convert non ...
Cited by 12 - Web Search - med.umich.edu - pubmedcentral.gov - dx.doi.org - all 8 versions »

Increased expression of the distal, but not of the proximal, Gata 1 transcripts during … - Full text - MIT Libraries
AM Vannucchi, S Linari, CS Lin, MJ Koury, MC … - Journal of Cellular Physiology, 1999 - doi.wiley.com
... an increase in the expression of Eklf, Scl, and Nfe2, three genes required for
erythroid differentiation, and preceded by 24 h the repression of Gata2 and Myb ...
Cited by 9 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

LMO3 Interacts with Neuronal Transcription Factor, HEN2, and Acts as an Oncogene in Neuroblastoma - Full text - MIT Libraries
M Aoyama, T Ozaki, H Inuzuka, D Tomotsune, J … - Cancer Research, 2005 - cancerres.aacrjournals.org
... On the other hand, a stable complex comprising LMO2, TAL1, and GATA1 was ... Our preliminary
data have suggested that GATA2, GATA3, GATA4, and GATA6 are highly ...
Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

Identification of novel vascular endothelial–specific genes by the microarray analysis of the … - Full text - MIT Libraries
S Sumanas, T Jorniak, S Lin - Blood, 2005 - bloodjournal.org
... Scl/tal1 transcription factor functions at the level of hemangioblast, affecting
both ... 7-9 Transcription factors including gata2, gata1, cmyb, and transcription ...
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Zebrafish myelopoiesis and blood cell development
K Hsu, JP Kanki, AT Look - Curr Opin Hematol, 2001 - co-hematology.com
... known mammalian hematopoietic transcription factor genes such as Gata-2, Tal1/Scl,
and ... cells appear later than those expressing scl, lmo2 and gata2, and this ...
Cited by 8 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

The 25th Volume: Role of the GATA Family of Transcription Factors in Andrology
RS VIGER, H TANIGUCHI, NM ROBERT, JJ TREMBLAY - andrologyjournal.org
... especially the testis, which is described next, target genes for GATA2 in the ... Ono
Y, Fukuhara N, Yoshie O. TAL1 and LIM-only proteins synergistically induce ...
Web Search

Gene expression profile of human endothelial cells exposed to sustained fluid shear stress - Full text - MIT Libraries
SM Wasserman, F Mehraban, LG Komuves, RB Yang, JE … - Physiol Genomics, 2002 - intl-physiolgenomics.physiology.org
... 3, C–D). GATA2 and Jagged2 have been implicated in the differentiation of ... of
endothelial-selective bHLH proteins, such as EPAS-1, bHLH-EC2, Tal1, and CLIF ...
Cited by 21 - Web Search - intl-physiolgenomics.physiology.org - physiolgenomics.physiology.org - ncbi.nlm.nih.gov

Enforced Activation of STAT 5 A Facilitates the Generation of Embryonic Stem-Derived Hematopoietic … - Full text - MIT Libraries
JJ Schuringa, K Wu, G Morrone, MAS Moore - Stem Cells, 2004 - stemcells.alphamedpress.org
... GATA2 RNA was expressed in all samples, particularly at day 5, and was ... additionally
revealed a STAT5A(1*6)-induced upregulation of SCL/Tal1, Runx2, embryonic ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis - Full text - MIT Libraries
R Ferreira, K Ohneda, M Yamamoto, S Philipsen - Mol Cell Biol, 2005 - mcb.asm.org
... GATA1, GATA2, and GATA3 belong to the hematopoietic subfamily, since they are expressed
mainly in the hematopoietic system (Fig. 2) (121). ... (i) GATA2. ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 … - Full text - MIT Libraries
V Valverde-Garduno, B Guyot, E Anguita, I Hamlett, … - Blood, 2004 - bloodjournal.org
... GATA1 and GATA2 have been implicated in promoting GATA1 expression 16,49 ) and
E-boxes that can bind the hematopoietic transcription factor SCL/Tal1 (hereafter ...
Cited by 3 - Web Search - dx.doi.org - bloodjournal.org - ncbi.nlm.nih.gov

GATA-1- and FOG-dependent Activation of Megakaryocytic alpha IIB Gene Expression - Full text - MIT Libraries
P Gaines, JN Geiger, G Knudsen, D Seshasayee, DM … - J Biol Chem, 2000 - jbc.org
... 1 (and/or FOG-GATA-2) complexes via its potential to bind Tal1-Lmo2 complexes ... We
thank Dr. Stuart Orkin for pEFNeoFOG and pUC-GATA2, Dr. Barbara Graves for pKS ...
Cited by 18 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The making of an erythroid cell
AR Migliaccio, G Migliaccio - Biotherapy, 1998 - ingentaconnect.com
... cells, eosinophils, Sertoli cells. GATA2 (A/T)GATA (A/G) Progenitor cells,
megakaryocytes, mast cells, brain cells. b-ZIP NFE2 TGAGTCA ...
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Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor … - Full text - MIT Libraries
Y Fujiwara, CP Browne, K Cunniff, SC Goff, SH … - Developmental Biology, 1996 - dx.doi.org
... Home page, Development Home page Y Zhou, M Yamamoto, and J. Engel GATA2 is required
for the generation of V2 interneurons Development, January 9, 2000; 127(17 ...
Cited by 165 - Web Search - pnas.org - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 7 versions »

Cloning and developmental expression of the murine homolog of the acute leukemia proto-oncogene AF 4 - Full text - MIT Libraries
K Baskaran, F Erfurth, G Taborn, NG Copeland, DJ … - Oncogene, 1997 - nature.com
... of the hematopoietic transcription factors AML1 (Okuda et al., 1996), GATA2 (Tsai
et al., 1994), Ttg2/rbnt2 (Warren et al., 1994) and SCL/tal1 (Shivdasani et al ...
Cited by 13 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Physiol. Genomics Articles in PresS. Published on November 5, 2002 as DOI 10.1152/physiolgenomics. …
SM Wasserman, F Mehraban, LG Komuves, RB Yang, JE … - physiolgenomics.physiology.org
... vessel wall in vivo (Fig. 2C-D). GATA2 and Jagged2 have been implicated in the
differentiation of ... bHLH-EC2, Tal1 and CLIF, have been described. ...
Web Search

GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei - Full text - MIT Libraries
JH van Doorninck, J van der Wees, A Karis, E … - J. Neurosci, 1999 - jneurosci.org
... SH (1994) An early haematopoietic defect in mice lacking the transcription factor
GATA2. ... an erythroid, DNA-binding complex which includes the TAL1, E47, GATA1 ...
Cited by 29 - Web Search - jneurosci.org - ncbi.nlm.nih.gov

Initiation of murine embryonic erythropoiesis: a spatial analysis - Full text - MIT Libraries
L Silver, J Palis - Blood, 1997 - bloodjournal.org
... gastrulation through the ordered temporal expression of tal-1, rbtn2, GATA2, and
GATA ... LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present ...
Cited by 40 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Coexpression of SCL and GATA 3 in the V 2 interneurons of the developing mouse spinal cord - Full text - MIT Libraries
E Smith, M Hargrave, T Yamada, CG Begley, MH … - Developmental Dynamics, 2002 - doi.wiley.com
... complex which includes the TAL1, E4, GATA-1 and Ldb1/NLI proteins. The EMBO Journal
16:3145–3157. Zhou Y, Yamamoto M, Engel JD. 2000. GATA2 is required for ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish … - Full text - MIT Libraries
M Kobayashi, K Nishikawa, M Yamamoto - Development, 2001 - dev.biologists.org
... It is intriguing to note that not only the gata1 gene, but other family members
of the hematopoietic GATA factor family, gata2 and gata3, contain the first ...
Cited by 17 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

[BOOK] Transcriptional regulation of endothelial cell-specific Tie1 and Vegfr3 genes
K Iljin - 2003 - ethesis.helsinki.fi
Page 1. Helsinki University Biomedical Dissertations No. 28 Transcriptional regulation
of endothelial cell-specific Tie1 and Vegfr3 genes Kristiina Iljin ...
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Genetics of mouse growth
A Efstratiadis - Int. J. Dev. Biol, 1998 - ijdb.ehu.es
... Nkx2-5 (17) Drosophila NK2 transcription factor related locus 5 GR e9.0; death
e11.0 Tal1 (4) T cell acute lymphocytic leukemia 1 GR e8.75; death by e11.5 ...
Cited by 88 - View as HTML - Web Search - ncbi.nlm.nih.gov - ijdb.ehu.es - Get it from MIT Libraries

SCL/tal-1-dependent process determines a competence to select the definitive hematopoietic lineage … - Full text - MIT Libraries
M Endoh, M Ogawa, S Orkin, S Nishikawa - The EMBO Journal, 2002 - embojournal.npgjournals.com
... On the other hand, SCL, LMO2 and GATA2, which are essential for HPC ... M., Davis,L.,
Oppenheimer-Marks,N. and Baer,R. (1993) Expression of the TAL1 proto-oncogene ...
Cited by 15 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

A novel E 2 box-GATA element modulates Cdc 6 transcription during human cells polyploidization - Full text - MIT Libraries
N Vilaboa, R Bermejo, P Martinez, R Bornstein, C … - Nucleic Acids Research, 2004 - nar.oupjournals.org
... non-immune goat serum (Goat NI), rabbit anti-GATA-2 antibody ( -GATA2) or non ... The
formation of a multimeric complex formed by GATA-1, Tal1, E47, Lmo2 and Ldb1A ...
Cited by 1 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

BMC Biotechnology - Full text - MIT Libraries
BMC Biotechnology - BMC Biotechnology, 2005 - biomedcentral.com
... transcription factors (GATA2, Fli1, Trp53, Mdm2, JUN, FOS, MAD, MAX). Over ... fusions.
These included CDK2, FLI1, CDKN-1B, mdm2, GATA2, Ephb2(LB) and ...
View as HTML - Web Search - dx.doi.org - gdrs-intranet.ath.cx - botany.sinica.edu.tw - all 6 versions »

Mutant-specific gene programs in the zebrafish - Full text - MIT Libraries
GJ Weber, SE Choe, KA Dooley, NN Paffett-Lugassy, … - Blood, 2005 - bloodjournal.org
Institution: Google Indexer Sign In as Individual. Blood, 15 July 2005, Vol.
106, No. 2, pp. 521-530. Prepublished online as a Blood ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the-globin … - Full text - MIT Libraries
L Elnitski, J Li, CT Noguchi, W Miller, R Hardison - J. Biol. Chem, 2001 - jbc.org
... In particular, GATA1 and/or GATA2 (26, 33, 45, 46), basic helix-loop-helix proteins
and other E box-binding proteins (32), HS2NFE5 (47), and proteins binding ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov

Expression of genes involved in vascular development and angiogenesis in endothelial cells freshly … - Full text - MIT Libraries
CJ Favre, M Mancuso, K Maas, JW McLean, P Baluk, … - Am. J. Physiol. Heart. Circ. Physiol, 2003 - ajpheart.physiology.org
Page 1. Am. J. Physiol.- Heart & Circ. Physiol. #H-00983-2002.R1 FINAL ACCEPTED
VERSION June 27, 2003 Expression of genes involved in vascular development ...
Cited by 12 - Web Search - intl-ajpheart.physiology.org - ajpheart.physiology.org - ncbi.nlm.nih.gov

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