TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - Mol. Cell. Biol, 1998 - mcb.asm.org
... presence of LMO2, HA-TAL1 was coimmunoprecipitated with FLAG-GATA3, suggesting that
LMO2 is capable of bridging TAL1 and GATA3 to form a complex in vivo (Fig. ...
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Transcriptional activity of TAL 1 in T cell acute lymphoblastic leukemia(T-ALL) requires RBTN 1 or-2 … - Full text - MIT Libraries
Y Ono, N Fukuhara, O Yoshie - J Biol Chem, 1997 - jbc.org
... We also examined direct binding between TAL1 and GATA3 by the same protocol
using MBP-TAL1 fusion protein and GST-GATA3 fusion protein. ...
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Formation of in vivo Complexes Between the TAL1 and E2A Polypeptides of Leukemic T Cells - Full text - MIT Libraries
H Hsu, I Wadman, R Baer - Proceedings of the National Academy of Sciences - pnas.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
Cited by 65 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

The LIM Protein RBTN2 and the Basic Helix-Loop-Helix Protein TAL1 are Present in a Complex in … - Full text - MIT Libraries
VE Valge-Archer, H Osada, AJ Warren, A Forster, J … - Proceedings of the National Academy of Sciences - pnas.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
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mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or … - Full text - MIT Libraries
S Huang, SJ Brandt - Mol Cell Biol, 2000 - mcb.asm.org
... All rights reserved. mSin3A Regulates Murine Erythroleukemia Cell Differentiation
through Association with the TAL1 (or SCL) Transcription Factor. ...
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Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 … - Full text - MIT Libraries
Z Xu, S Huang, LS Chang, AD Agulnick, SJ Brandt - Mol Cell Biol, 2003 - pubmedcentral.nih.gov
... TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2
expression ... cell acute lymphoblastic leukemia by acting as cofactors for GATA3.
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ROLE OF THE TAL1/SCL TRANSCRIPTION FACTOR IN NORMAL AND LEUKEMIC HEMATOPOIESIS
SJ BRANDT - doi.wiley.com
Page 1. CHAPTER 4 ROLE OF THE TAL1/SCL TRANSCRIPTION ... Translocations 3 to the TAL1
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A complex linkage in the developmental pathway of endothelial and hematopoietic cells
SI Nishikawa - Curr Opin Cell Biol, 2001 - cbi.pku.edu.cn
... The finding that tal1 (–/–) and lmo2 (–/–) ... Manaia et al. [16] observed GATA3 expression
in mesenchymal cells coinciding with a stromal activity to ...
Cited by 19 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

SCL and LMO 1 alter thymocyte differentiation: inhibition of E 2 A-HEB function and pre-T< img … - Full text - MIT Libraries
S Herblot, AM Steff, P Hugo, PD Aplan, T Hoang - Nature Immunology, 2000 - nature.com
... 9. Ono, Y., Fukuhara, N. & Yoshie, O. TAL1 and LIM-only proteins ... 2 expression in
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Involvement of the TCL5 Gene on Human Chromosome 1 in T-Cell Leukemia and Melanoma - Full text - MIT Libraries
LR Finger, J Kagan, G Christopher, J Kurtzberg, MS … - Development, 2004 - pnas.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
Cited by 60 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord … - Full text - MIT Libraries
R Haddad, P Guardiola, B Izac, C Thibault, J … - Blood, 2004 - bloodjournal.org
... CD7 - HPCs displayed a more immature gene transcription profile with selective
expression of stem cell-associated transcription factors TAL1, GATA3, HLF, and ...
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protein GATAl - Full text - MIT Libraries
H OSADA, G GRUTZ, H AXELSON, A FORSTER, TH … - Proc. Natl. Acad. Sci. USA, 1995 - pnas.org
... involving RBTN2, TAL1, and GATA1, together with E47, the basic helix-loop-helix
heterodimerization partner of TAL1, could be demonstrated. ...
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Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem … - Full text - MIT Libraries
S Gerecht-Nir, JE Dazard, M Golan-Mashiach, S … - Developmental Dynamics, 2005 - doi.wiley.com
... related receptors FLT1, FLT4, PDGFRB, TGF R2, and TGF R3, other markers such as
CD34, VCAM1, PECAM1, VE-CAD, and transcription factors TAL1, GATA2, and GATA3. ...
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The Gene SCL is Expressed during Early Hematopoiesis and Encodes a Differentiation-Related DNA- … - Full text - MIT Libraries
CG Begley, PD Aplan, SM Denning, BF Haynes, TA … - Blood, 2005 - pnas.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
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Analysis of the relationship between Scl transcription factor complex protein expression patterns …
AM Rice, KM Holtz, J Karp, S Rollins, AC … - Leuk Res, 2004 - ncbi.nlm.nih.gov
... Exogenous expression of the transcription factor Scl (Tal1) in WEHI-3B D+
myelomonocytic ... while the levels of expression of Rbtn1, GATA2, and GATA3 were absent ...
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LMO3 Interacts with Neuronal Transcription Factor, HEN2, and Acts as an Oncogene in Neuroblastoma - Full text - MIT Libraries
M Aoyama, T Ozaki, H Inuzuka, D Tomotsune, J … - Cancer Research, 2005 - cancerres.aacrjournals.org
... reported that LMO2 and TAL1 act as cofactors for GATA3 to induce the expression
of the retinaldehyde dehydrogenase 2 gene in T-cell ALL (39). ...
Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell … - Full text - MIT Libraries
T Boehm, L Foroni, Y Kaneko, MF Perutz, TH … - Proceedings of the National Academy of Sciences - pnas.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
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The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid … - Full text - MIT Libraries
JE Visvader, X Mao, Y Fujiwara, K Hahm, SH Orkin - Proc Natl Acad Sci USA, 1997 - dx.doi.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
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Absence of Yolk sac Hematopoiesis from Mice with a Targeted Disruption of the scl Gene - Full text - MIT Libraries
L Robb, I Lyons, R Li, L Hartley, F Kontgen, RP … - Proceedings of the National Academy of Sciences - pnas.org
... S. Fichelson, PH Romeo, A. Dubart-Kupperschmitt, and F. Pflumio Characterization
of DNA-binding-dependent and -independent functions of SCL/TAL1 during human ...
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Structure and function of the SCL/TAL-1 containing transcriptinal complexes in erythropoiesis and …
L Maouche-Chretien - john-libbey-eurotext.fr
... 54. Ono Y, Fukuhara N, Yoshie O. TAL1 and LIM-only proteins synergistically induce ...
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Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in … - Full text - MIT Libraries
LW Jurata, DA Kenny, GN Gill - Developmental Biology, 1996 - dx.doi.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3 Mol ...
Cited by 113 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Helix-loop-helix(E 2-5, HEB, TAL 1 and Id 1) protein interaction with the TCRalphadelta enhancers - Full text - MIT Libraries
M Bernard, E Delabesse, L Smit, C Millien, IR … - International Immunology, 1998 - intimm.oupjournals.org
... 1998 Oxford University Press Helix-loop-helix (E2-5, HEB, TAL1 and Id1) ... TCR
[αE1-2] activity was partially (40%) inhibited by TAL1 but not at all by Id1. ...
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Arthur Sackler Colloquia Home Help [Feedback][For Subscribers][Archive][Search][Contents] - Full text - MIT Libraries
A Skapenko, J Leipe, U Niesner, K Devriendt, R … - J. Exp. Med, 2004 - pnas.org
... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ... 2 Expression
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Transcription factors in hematopoiesis
I Engel, C Murre - Curr. Opin. Genet. Dev, 1999 - www-biology.ucsd.edu
... Ono Y, Fukuhara N, Yoshie O: TAL1 and LIM-only proteins • synergistically induce ...
in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3. ...
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In Silico Identification of Regulatory Elements of GRIN 1 Genes
MK Mejia-Guerra, LR Lareo - Omics A Journal of Integrative Biology, 2005 - dx.doi.org
... 100 to 200 Tal1 - Tal1 - Tal1 - 47S, 47S 47S, CFI-USP CFI-USP ... 700 to 600 GATA1, GATAX,
CdxA SRY Mkx-2 GATA2, GATA1 GATA3 600 to 500 GATA1 Sp1 Mkx-2 ...
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Cellular Gene Expression upon Human Immunodeficiency Virus Type 1 Infection of CD4-T-Cell Lines - Full text - MIT Libraries
MG Katze, RE Bumgarner, GK Geiss, JI Mullins - Journal OF Virology, 2003 - jvi.asm.org
... down-regulated (eg, MYC), a small group of transcription factors including EGR1,
JUN, TNRC3, DRPLA, ARP, SMARCD2, SP140, GATA3, RELB, ELF1, and TAL1 were up ...
Cited by 29 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive … - Full text - MIT Libraries
MC Nawijn, R Ferreira, GM Dingjan, O Kahre, D … - J. Immunol, 2001 - jimmunol.org
... In two independent CD2-GATA3-transgenic lines, 50% of the mice developed thymic
lymphoblastoid tumors that were CD4 + CD8 +/low and mostly CD3 + . ...
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Coexpression of SCL and GATA 3 in the V 2 interneurons of the developing mouse spinal cord - Full text - MIT Libraries
E Smith, M Hargrave, T Yamada, CG Begley, MH … - Developmental Dynamics, 2002 - doi.wiley.com
... The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding
complex which includes the TAL1, E4, GATA-1 ... COEXPRESSION OF SCL AND GATA3
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SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain … - Full text - MIT Libraries
S Herblot, AM Steff, P Hugo, PD Aplan, T Hoang - Nat Immunol, 2000 - nature.com
Nature immunology is an immunology journal publishing science articles and research
papers on topics such as immune systems, immune deficiency, etc.
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P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor … - Full text - MIT Libraries
S Huang, Y Qiu, Y Shi, Z Xu, SJ Brandt - The EMBO Journal, 2000 - embojournal.npgjournals.com
... P/CAF-mediated acetylation regulates the function of the basic helix–loop–helix
transcription factor TAL1/SCL. ... (A) TAL1 acetylation in vivo. ...
Cited by 22 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

Transcriptional Control of T Lymphocyte Differentiation - Full text - MIT Libraries
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - Stem Cells, 2001 - stemcells.alphamedpress.org
... TCRA enhancer could be inhibited by the class II bHLH factor TAL1 [69]. ... Targeted
disruption of the GATA3 gene causes severe abnormalities in the nervous system ...
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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid … - Full text - MIT Libraries
GA Blobel, T Nakajima, R Eckner, M Montminy, SH … - Biochemistry, 1998 - dx.doi.org
... Home page M. Yamashita, M. Ukai-Tadenuma, M. Kimura, M. Omori, M. Inami, M. Taniguchi,
and T. Nakayama Identification of a Conserved GATA3 Response Element ...
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Gradient of E2A activity in B-cell development - Full text - MIT Libraries
S Herblot, PD Aplan, T Hoang - Mol Cell Biol, 2002 - mcb.asm.org
... Ectopic expression in the B lineage of SCL/Tal1, a tissue-specific bHLH factor that
inhibits E2A function, blocks commitment into the B lineage without ...
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Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor … - Full text - MIT Libraries
Y Fujiwara, CP Browne, K Cunniff, SC Goff, SH … - Developmental Biology, 1996 - dx.doi.org
... Crowe, A. Dobbie, G. Hampson, I. Holdaway, MA Levine, R. McWilliams, S. Rigden,
J. Sampson, AJ Williams, and RV Thakker Characterization of GATA3 Mutations in ...
Cited by 165 - Web Search - pnas.org - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 7 versions »

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms - Full text - MIT Libraries
ME Massari, C Murre, R Articles - Mol. Cell. Biol, 2000 - dx.doi.org
... The bHLH protein SCL/Tal1, originally discovered by virtue of its involvement in
a T-cell acute lymphoblastic leukemia (T-ALL)-specific translocation, has been ...
Cited by 292 - Web Search - mcb.asm.org - www-biology.ucsd.edu - sig.biostr.washington.edu - all 9 versions »

S tem C ells
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - immuneweb.xxmc.edu.cn
... MyoD, Myf 5, MASH, HASH, TAL1, as-c Class III bHLH-zip proteins ... These include a
microdeletion on chromosome 1p32 harboring the TAL1 or SCL gene [51], and transl
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E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... as pro-T cells, the E2a/Pbx1 outgrowths expressed the pro-T-cell genes c-kit (SCF
receptor), Scl/tal1, IL-7 receptor α, E2A, Ikaros, PU.1, GATA3, and ID2 (Fig ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without … - Full text - MIT Libraries
C Porcher, EC Liao, Y Fujiwara, LI Zon, SH Orkin - Development, 1999 - dev.biologists.org
Page 1. INTRODUCTION Blood cell production in vertebrates occurs in successive
waves in development, first in the extraembryonic ...
Cited by 43 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Decoding Hematopoietic Specificity in the Helix-Loop-Helix Domain of the Transcription Factor SCL/ … - Full text - MIT Libraries
TM Schlaeger, A Schuh, S Flitter, A Fisher, H … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2
expression ... cell acute lymphoblastic leukemia by acting as cofactors for GATA3. ...
Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Ectopic expression of TAL-1 protein in Ly-6E. 1-htal-1 transgenic mice induces defects in B-and T- … - Full text - MIT Libraries
N Goardon, A Schuh, I Hajar, X Ma, H Jouault, E … - Blood, 2002 - bloodjournal.org
... Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development
and potentiates T cell tumorigenesis in transgenic mice. ...
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State-of-the-Art Review on Vascular Stem Cells and Angiogenesis
AJC BLOOR, J SANCHEZ, AR GREEN, B GOeTTGENS - JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2002 - dx.doi.org
Page 1. JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH 11:195–206 (2002) ©
Mary Ann Liebert, Inc. State-of-the-Art Review on Vascular ...
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Ectopic expression ofTAL-1 protein in Ly-6E. 1-htal-1 transgenic mice induces defects in B-andT- …
L Maouche-Chretien - BLOOD, 2002 - bloodjournal.org
Page 1. HEMATOPOIESIS Ectopic expression ofTAL-1 protein in Ly-6E.1-htal-1 transgenic
mice induces defects in B- andT-lymphoid differentiation ...
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The 25th Volume: Role of the GATA Family of Transcription Factors in Andrology
RS VIGER, H TANIGUCHI, NM ROBERT, JJ TREMBLAY - andrologyjournal.org
... Ono Y, Fukuhara N, Yoshie O. TAL1 and LIM-only proteins synergistically induce ... in
T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3. ...
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Lmo2 and GATA-3 associated expression in intraembryonic hemogenic sites - Full text - MIT Libraries
A Manaia, V Lemarchandel, M Klaine, I Max-Audit, P … - Development, 2000 - dev.biologists.org
Page 1. INTRODUCTION In the mouse embryo, the yolk sac (YS) and the caudal
intraembryonic splanchnopleura (Sp) independently generate hemopoietic precursors. ...
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Different sequence requirements for expression in erythroid and megakaryocytic cells within a … - Full text - MIT Libraries
P Vyas, MA McDevitt, AB Cantor, SG Katz, Y … - Development, 1999 - dev.biologists.org
Page 1. INTRODUCTION The hematopoietic system presents a well-characterized model
to investigate how multiple cell types arise from a common progenitor cell. ...
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Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 … - Full text - MIT Libraries
V Valverde-Garduno, B Guyot, E Anguita, I Hamlett, … - Blood, 2004 - bloodjournal.org
... GATA2 have been implicated in promoting GATA1 expression 16,49 ) and E-boxes that
can bind the hematopoietic transcription factor SCL/Tal1 (hereafter referred ...
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SCL assembles a multifactorial complex that determines glycophorin A expression - Full text - MIT Libraries
R Lahlil, E Lecuyer, S Herblot, T Hoang - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... SCL/TAL1 is a hematopoietic-specific transcription factor of the basic
helix-loop-helix (bHLH) family that is essential for erythropoiesis. ...
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Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding … - Full text - MIT Libraries
PE Mead, AE Deconinck, TL Huber, SH Orkin, LI Zon - Development, 2001 - dev.biologists.org
... TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2
expression ... cell acute lymphoblastic leukemia by acting as cofactors for GATA3. ...
Cited by 21 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei - Full text - MIT Libraries
JH van Doorninck, J van der Wees, A Karis, E … - J. Neurosci, 1999 - jneurosci.org
... Engel JD, Lindenbaum MH (1995) Targeted disruption of the GATA3 gene causes ... assembling
an erythroid, DNA-binding complex which includes the TAL1, E47, GATA1 ...
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Developmental control via GATA factor interplay at chromatin domains. - Full text - MIT Libraries
EH BRESNICK, ML MARTOWICZ, S PAL, KD JOHNSON - JOURNAL OF CELLULAR PHYSIOLOGY, 2005 - doi.wiley.com
Page 1. JOURNAL OF CELLULAR PHYSIOLOGY 205:1–9 (2005) REVIEW ARTICLES Developmental
Control via GATA Factor Interplay at Chromatin Domains ...
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