Progress in Hematology
Y Hayashi - cardenjennings.metapress.com
... is significantly associated with a favorable prognosis, whereas expression of TAL1,
LYL1, or ... TYMS) were down-regulated and major HOX genes (HOXA9, HOXA10, HOXC6 ...
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Conserved noncoding sequences are reliable guides to regulatory elements
RC Hardison - Trends Genet, 2000 - ebc.ee
... 13 found that some noncoding sequences of the SCL/TAL1 gene are strongly conserved
between human and chicken, and they showed ... HOXA10 1 2 HOXA9 1 2 HOXA7 1 2 ...
Cited by 165 - View as HTML - Web Search - dx.doi.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Molecular Cytogenetics A new recurrent inversion, inv (7)(p15q34), leads to transcriptional …
F Speleman, B Cauwelier, N Dastugue, J Cools, B … - Leukemia, 2005 - nature.com
... RBTN1 on 11p15, RBTN2 on 11p13, HOX11 on 10q24, TAN1 on 9q34, TAL1(SCL) on ... 16 Primers
for the other HOXA genes (HOXA2, HOXA3, HOXA6, HOXA9, HOXA10, HOXA13) and ...
Web Search - nature.com

t (4; 11)(q 21; p 15) translocation involving NUP 98 and RAP 1 GDS 1 genes: characterization of a … - Full text - MIT Libraries
C Mecucci, R La Starza, M Negrini, S Sabbioni, B … - British Journal of Haematology, 2000 - blackwell-synergy.com
... of partners, including rhombotin 1 and 2 at 11p15, HOX11 at 10q24, TAL1 at 1p32 ...
indication is also supported by the finding that the NUP98-HOXA9 fusion protein ...
Cited by 8 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

A new recurrent inversion, inv (7)(p15q34), leads to transcriptional activation of
F Speleman, B Cauwelier, N Dastugue, J Cools, B … - Leukemia, 2005 - nature.com
... RBTN1 on 11p15, RBTN2 on 11p13, HOX11 on 10q24, TAN1 on 9q34, TAL1(SCL) on ... 16 Primers
for the other HOXA genes (HOXA2, HOXA3, HOXA6, HOXA9, HOXA10, HOXA13) and ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development
and potentiates ... Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL … - Full text - MIT Libraries
J Soulier, E Clappier, JM Cayuela, A Regnault, M … - Blood, 2005 - bloodjournal.org
... in a genomic region of 2.6-kb length located between the HOXA10 and HOXA9 genes
(BCR ... mechanisms of HOXA activation, as has also been reported for TAL1 and TLX1 ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Transcriptional Regulation of Cardiac Progenitor Cell Populations - Full text - MIT Libraries
AM Masino, TD Gallardo, CA Wilcox, EN Olson, RS … - Circulation Research, 2004 - circresaha.org
... Specifically, Tal1 may function in inhibiting myogenesis; Tal1 suppressed myotube
fusion in ... of the genes we found to be cardiac enriched (Dlx2, Hoxa9, and Hoxd9 ...
Cited by 2 - Cached - Web Search - circres.ahajournals.org - ahavj.ahajournals.org - ncbi.nlm.nih.gov - all 7 versions »

PROGRESOS EN EL TRASPLANTE HEMOPOYETICO ALOGENICO
E DE ENFERMEDAD, R MINIMA - db2.doyma.es
... LLA-T Del1p TAL1 25 T(11;14) RHOM2-TCRD 7 T(10;14) HOX-TCRD 4 T(1;14) TAL1-TCRD
3 ... BCR-ABL < 1 T(6;9) DEK-CAN < 1 T(16;21) FUS-ERG < 1 T(7;11) NUP98-HOXA9 < 1 T ...
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[CITATION] Acute Lymphoblastic Leukemia
MG Alterations
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The use of genetic microarray analysis to classify and predict prognosis in haematological … - Full text - MIT Libraries
AP Levene, GJ Morgan, FE Davies - Clinical and Laboratory Haematology, 2003 - blackwell-synergy.com
... Significantly, HOXA9 is deregulated by the t(7;11)(p15;p15) chromosomal ... of oncogenic
transcription factors identified the association of HOX11, TAL1 and LYL1 ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Chromosomal abnormalities and tumor development: from genes to therapeutic mechanisms - Full text - MIT Libraries
C Cobaleda, J Perez-Losada, I Sanchez-Garcia - BioEssays, 1998 - doi.wiley.com
... BTG t(7;19)(q35;p13) T-ALL TCR- , LYL1 t(1;14)(p32;q11) T-ALL TAL1/SCL, TCR ...
t(6;9)(p23;q34) ANLL DEK, CAN/NUP214 t(7;11)(p15;p15) ANLL (M2, M4) HOXA9, NUP98 ( ...
Cited by 13 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Genomic approaches to the pathogenesis and treatment of acute lymphoblastic leukemias
SA Armstrong, JJD Hsieh, SJ Korsmeyer - Current Opinion in Hematology, 2002 - co-hematology.com
... Gene expression suggests that LYL1, Hox11, and TAL1 expressing T-ALLs are arrested
at ... T, Feinstein E, Mor O, et al.: Upregulation of Meis1 and HoxA9 in acute ...
Cited by 1 - Web Search - co-hematology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

acquises de la cellule souche hematopoietique ou d’un precurseur deja commis vers les lignees …
S YNTHESE - MEDECINE/SCIENCES, 2003 - ist.inserm.fr
... à des complexes transcriptionnels comme les protéines LYL1, TAL1/SCL, LMO1 et ... LAM
secondaires (protéine associée au pore nucléaire) HOXA9 (7p15) Facteur ...
View as HTML - Web Search - erudit.org

CONSEQUENCES OF CHROMOSOMAL ABNORMALITIES IN TUMOR DEVELOPMENT - Full text - MIT Libraries
I Sanchez-Garcia - Annual Review of Genetics, 1997 - dx.doi.org
... specific chromosomal deletion that involved the 5' side of the gene TAL1/SCL and
a ... The NUP98-HOXA9 fusion (15, 91) may also be considered within this framework ...
Cited by 25 - Web Search - wwwlib.bionet.nsc.ru - genet.annualreviews.org - ncbi.nlm.nih.gov - all 6 versions »

Blood First Edition Paper, prepublished online November 2, 2004; DOI 10.1182/blood-2004-09-3459
P Isolation, GGE Analysis - uni-ulm.de
... very strong in EP, and absent (Fog1) and low (Tal1) in GMP. Within the homeobox
domain gene family, only HoxA9 was expressed, with lower expression in EP and ...
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Inaugural-Dissertation zur Erlangung des Doktorgrades der Naturwissenschaftlichen Fakultaet der …
U Fuchs - deposit.ddb.de
Page 1. Charakterisierung der 11q23/MLL-Fusionspartnergene GRAF und FBP17
Inaugural-Dissertation zur Erlangung des Doktorgrades der ...
Web Search - bibl7.hrz.uni-giessen.de - geb.uni-giessen.de - bibd.uni-giessen.de

The Kinetic Status of Hematopoietic Stem Cell Subpopulations Underlies a Differential Expression of … - Full text - MIT Libraries
R Manfredini, R Zini, S Salati, M Siena, E … - Stem Cells, 2005 - stemcells.alphamedpress.org
... In particular, we showed that CD34 + cells coexpress HOXA9 and its cofactors ... assembling
an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 ...
Web Search - dx.doi.org - stemcells.alphamedpress.org - ncbi.nlm.nih.gov

Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit ( … - Full text - MIT Libraries
G Terszowski, C Waskow, P Conradt, D Lenze, J … - Blood, 2005 - bloodjournal.org
... Zfpm1) and Tal1 expressions were very strong in EPs and absent (Fog1) and low (Tal1)
in GMPs. Within the homeobox domain gene family, only HoxA9 was expressed ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells - Full text - MIT Libraries
H Ohta, A Sawada, JY Kim, S Tokimasa, S Nishiguchi … - J Exp Med, 2002 - jem.org
... c-Mpl), transcription factors (c-jun, c-fos, c-myc, c-myb, tal1/SCL, AML1 ... Mice bearing
a targeted interruption of the homeobox gene HOXA9 have defects in myeloid ...
Cited by 29 - Web Search - intl.jem.org - ncbi.nlm.nih.gov

CBP/p300 in cell growth, transformation, and development - Full text - MIT Libraries
RH Goodman, S Smolik - Development, 2000 - genesdev.org
... translocation, the amino terminus of the nuclear pore complex (NPC) protein NUP98
is fused onto the carboxyl terminus of the homeotic transcription factor HOXA9 ...
Cited by 393 - Web Search - genesdev.org - genesdev.org - ncbi.nlm.nih.gov - all 5 versions »

Exploitation of stem cell plasticity - Full text - MIT Libraries
E Martin-Rendon, SM Watt - Transfusion Medicine, 2003 - blackwell-synergy.com
... Overexpression of HoxA9 in HSCs induces stem cell expansion (Thorsteinsdottir et
al., 2002), whereas HoxA5 and HoxA10 perturb their differentiation activity ...
Cited by 4 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Fifty years of studies of the biology and therapy of childhood leukemia - Full text - MIT Libraries
JH Kersey - Blood, 1997 - bloodjournal.org
... lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus:
A ... Shaughnessy JD Jr: Fusion of the nucleoporin gene NUP98 to HOXA9 by the ...
Cited by 74 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Cytogenetic and FISH Studies in Myelodysplasia, Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia …
II Supplement - Genetic Testing - ishapd.org
... TAL1, MLL AF1r, MLL TAL1, TCRad ?, RARa PBX1, E2A Igk, BCL6 ALK, NPM Igk, c-MYC ... PDGFRB,
TEL IL3, IgH NPM, RARa DEK, CAN AF6, MLL IRF4, IgH HOXA9, NUP98 FGFR1 ...
View as HTML - Web Search - haem.nus.edu.sg

The granulocytic inducer C/EBP a inactivates the myeloid master regulator PU. 1: possible role in …
AMK und Poliklinik, III am Klinikum Grosshadern - edoc.ub.uni-muenchen.de
... positively regulates granulocytic/monocytic differentiation, whereas its
down-regulation is necessary for progression of erythropoiesis HOXA9 important role ...
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6 RECURRING CHROMOSOME REARRANGEMENTS IN HUMAN CANCER
OI Olopade, OM Sobulo, JD Rowley - cancer.org
... q13) AML t(3;3)(q21;q26) RPN1-EVI1 Or inv(3)(q21;q26)\ t(3;5)(q21;q31)
t(3;5)(q25;q34) MLF1-NPM1 t(6;9)(p23;q34) DEK-CAN (NUP214) t(7;11)(p15;p15) HOXA9- ...
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Towards an integrated classification of adult acute lymphoblastic leukemia - Full text - MIT Libraries
R Foa, A Vitale - Reviews in Clinical and Experimental Hematology, 2002 - blackwell-synergy.com
... errors which juxtapose the proto-oncogene to regulatory Ig/TCR sequences, leading
to deregulated protein expression, for example the SIL-TAL1/tal d deletions ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov

Gene expression profiling and its application in studies of haematological malignancy - Full text - MIT Libraries
M Hubank - British Journal of Haematology, 2004 - blackwell-synergy.com
... et al (2002) applied hierarchical clustering to T-ALL tumours and showed clustering
of tumours associated with dysregulation of HOX11, TAL1, LYL1, LMO1 and LMO2 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Bibliography Current World Literature
JY Bertrand, S Giroux, R Golub… - Current Opinion in Hematology, 2005 - co-hematology.com
... Blood 2004, 104:2307-2314. • Dorsam ST, Ferrell CM, Dorsam GP, et al.: The
transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells. ...
Web Search - co-gastroenterology.com - co-ophthalmology.com - coronary-artery.com

[BOOK] Cytogenetic and molecular genetic changes in childhood acute leukaemias
T Niini - 2002 - ethesis.helsinki.fi
... t(2;8)(p12;q24) MYC Relocation to IgK TF <1 Immature B t(1;14)(p32;q11) TAL1 Relocation
to TCRδ TF <1 T t(1;7)(p32;q34) TAL1 Relocation to TCRβ TF <1 T ...
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Bibliography Current World Literature
H Ashush, LA Rozenszajn, M Blass, M Barda-Saad, D … - Current Opinion in Oncology, 2001 - co-oncology.com
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