Phosphorylation of the TAL1 oncoprotein by the extracellular-signal-regulated protein kinase ERK1 - Full text - MIT Libraries
JT Cheng, MH Cobb, R Baer - Mol Cell Biol, 1993 - pubmedcentral.nih.gov
... Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic ...
chromosome breakage 25 kilobase pairs downstream of the TAL1 protooncogene. ...
Cited by 33 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine … - Full text - MIT Libraries
AL Zaiman, A Nieves, J Lenz - J. Virol, 1998 - jvi.asm.org
... c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently
to ... E-box sequence and context-dependent TAL1/SCL modulation of basic helix ...
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Measurement of SIL–TAL1 fusion gene transcripts associated with human T-cell lymphocytic leukemia …
JD Curry, MT Smith - Leukemia Research, 2003 - ehscenter.berkeley.edu
... Measurement of SIL–TAL1 fusion gene transcripts associated ... A reverse transcriptase
real-time PCR assay to quantify SIL–TAL1 fusion genes is described. ...
Cited by 1 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

Expression of alpha4-integrin defines the earliest precursor of hematopoietic cell lineage diverged … - Full text - MIT Libraries
M Ogawa, M Kizumoto, S Nishikawa, T Fujimoto, H … - Blood, 1999 - bloodjournal.org
... 4-integrin fraction also indicates that these mature primitive erythrocytes contributed
to neither the expression of the Gata2, Tal1, and Myb genes detected by ...
Cited by 35 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

A complex linkage in the developmental pathway of endothelial and hematopoietic cells
SI Nishikawa - Curr Opin Cell Biol, 2001 - cbi.pku.edu.cn
... The finding that tal1 (–/–) and lmo2 ... vascular remodelling Runt related transcription
factor 1 (Runx1), GATA-binding protein 2 (GATA2) and c-myb are group 2 ...
Cited by 19 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

transcripts including those of the PU. 1 gene - Full text - MIT Libraries
H Okada, T Watanabe, M Niki, H Takano, N Chiba, N … - Oncogene, 1998 - nature.com
... AML1 PEBP2 b/CBF b PEBP2 aA GATA1 GATA2 Ikaros Scl/tal1 PU.1 NFE2 c-Myb ¯k-1
¯k-2/¯t-3 ¯t-1 SCF c-Kit Epo Epo receptor M-CSF M-CSF receptor G-CSF G-CSF ...
Cited by 30 - Web Search - nature.com - ncbi.nlm.nih.gov

XIX Symposium of the International Association for Comparative Research on Leukemia and Related … - Full text - MIT Libraries
A Hochhaus, U Berger, A Kr& x 000 E 4 mer, A … - Journal of Cancer Research and Clinical Oncology, 1998 - springerlink.com
... normally involved in erythroid development that acts synergistically with TAL1 to
promote T ... that the avian leukemia virus E26 onco- gene v-myb down-regulates ...
Web Search

Transcription factors in hematopoiesis
I Engel, C Murre - Curr. Opin. Genet. Dev, 1999 - www-biology.ucsd.edu
... Furthermore, it was determined that c-myb –/– ES cells were also unable to ... SCL and
LMO proteins in normal and aberrant development The SCL/Tal1 gene (SCL ...
Cited by 10 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells - Full text - MIT Libraries
H Ohta, A Sawada, JY Kim, S Tokimasa, S Nishiguchi … - J Exp Med, 2002 - jem.org
... gp130, Epo receptor, G-CSF receptor, GM-CSF receptor, c-erbA , c-Mpl, c-jun, c-fos,
c-myc, c-myb, tal1/SCL, AML1, GATA1, GATA2, and PU.1. Expression of none of ...
Cited by 29 - Web Search - intl.jem.org - ncbi.nlm.nih.gov

Expression of Transcription Factors During Sodium Phenylacetate Induced Erythroid Differentiation in … - Full text - MIT Libraries
AV Rath, GE Schmahl, CM Niemeyer - Blood Cells, Molecules, and Diseases, 1997 - scripps.edu
... Constitutive c-myb expres- sion in K562 cells inhibits induced erythroid differ ... The
LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in ...
Cited by 2 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions »

Important roles of reversible acetylation in the function of hematopoietic transcription factors - Full text - MIT Libraries
X Huo, J Zhang - J. Cell. Mol. Med, 2005 - jcmm.org
... c-Myb P300 transcriptional activation not changed ... The amino-terminal sequence of
p300 and the bHLH domain of TAL1 interact in vitro, but the interaction does ...
View as HTML - Web Search - jcmm.ro - jcmm.org - ncbi.nlm.nih.gov

The Ets family contains transcriptional activators and repressors involved in angiogenesis - Full text - MIT Libraries
E Lelievre, F Lionneton, F Soncin, B Vandenbunder - Int J Biochem Cell Biol, 2001 - ingentaconnect.com
... Scl/Tal1 which is essential for angiogenic remodelling of the yolk sac capillary ...
D. Stehelin, Complementary patterns of expression of c-etsl, c-myb and c-myc ...
Cited by 35 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Multiple Proteins Binding to a GATA-E Box-GATA Motif Regulate the Erythroid Kruppel-like Factor(EKLF … - Full text - MIT Libraries
KP Anderson, SC Crable, JB Lingrel - J Biol Chem, 1998 - jbc.org
... Evidence for a model in which Lmo2 interacts with both GATA-1 and Tal1 serving as ...
discovered three Sp1 sites, two GATA sites, an E box motif, a c-myb site, and ...
Cited by 21 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

[BOOK] The Oncogene handbook
R Hesketh - 1994 - Academic Press
Cited by 21 - Web Search - Get it from MIT Libraries - Library Search

A transcription factor party during blood cell differentiation
MH Sieweke, T Graf - Curr. Opin. Genet. Dev, 1998 - ciml.univ-mrs.fr
... c-Maf can inhibit the synergistic activity of c-Ets-1 and c-Myb on the ... molecule
assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA ...
Cited by 62 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

NF-kappa B transcription factors are involved in normal erythropoiesis - Full text - MIT Libraries
MY Zhang, SC Sun, L Bell, BA Miller - Blood, 1998 - bloodjournal.org
... oligonucleotides covering the B sites from the IL-2R , c-myb, and c ... of erythroid
proliferation and differentiation include GATA-1, 34 SCL (or TAL1), and other ...
Cited by 25 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

RUNX1/AML1: a central player in hematopoiesis
T Okuda, M Nishimura, M Nakao, Y Fujita - Int J Hematol, 2001 - cardenjennings.metapress.com
... Tal1/SCL and LMO2/ rbtn2, and other factors, including RUNX1/AML1 (runt- related
transcription factor 1/acute myeloid leukemia 1), CBF (PEBP2 ), c-Myb, Pu.1 ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation - Full text - MIT Libraries
VM Richon, Y Webb, R Merger, T Sheppard, B Jursic, … - J. Clin. Oncol, 2005 - dx.doi.org
... resistant MEL cell variant, and differences in c-myb expression during ... Murine
Erythroleukemia Cell Differentiation through Association with the TAL1 (or SCL ...
Cited by 94 - Web Search - pnas.org - pubmedcentral.nih.gov - adsabs.harvard.edu - all 8 versions »

Transcriptional regulation of erythropoiesis - Full text - MIT Libraries
C Perry, H Soreq - Eur. J. Biochem, 2002 - content.febsjournal.org
... 653–660.[Medline]; Drake, CJ, Brandt, SJ, Trusk, TC & Little, CD (1997) TAL1/SCL
is ... Pietryga, DW, Scott, WJ Jr & Potter, SS (1991) A functional c-myb gene is ...
Cited by 11 - Cached - Web Search - ejbiochem.org - blackwell-synergy.com - ingentaconnect.com - all 8 versions »

An SL3-3 murine leukemia virus enhancer variant more pathogenic than the wild type obtained by … - Full text - MIT Libraries
S Ethelberg, AB Soerensen, J Schmidt, A Luz, FS … - J. Virol, 1997 - jvi.asm.org
... E-box sequence and context-dependent TAL1/SCL modulation of basic helix-loop- helix ...
Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3 ...
Cited by 11 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular … - Full text - MIT Libraries
EC Liao, BH Paw, AC Oates, SJ Pratt, JH … - Genes Dev, 1998 - genesdev.org
... Tal1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a
dorsal-to ... A functional c-myb gene is required for normal murine fetal hepatic ...
Cited by 103 - Web Search - genesdev.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Dependence of both spontaneous and antibody-dependent, granule exocytosis-mediated NK cell …
R Trotta, KA Puorro, M Paroli, L Azzoni, B Abebe, … - J. Immunol, 1998 - jimmunol.org
... The involvement of ERK in the control of gene expression via phosphorylation of
several transcription factors (eg, Elk 1, c-Myb, TAL1) is well established (43 ...
Cited by 36 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Transcription Factors: Normal and Malignant Development of Blood Cells
IJ Hematol - Int J Hematol, 2001 - cardenjennings.metapress.com
... GATA-1 and friend of GATA (FOG), nuclear factor erythroid 2 (NF-E2), TAL1/SCL,
erythroid ... is relatively short,with two chapters,one for myc and myb and another ...
Web Search

TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 4 Role of TAL1/SCL Transcription Factor in Normal and Leukemic Hematopoiesis ... 29 The
Roles of the c-myc and c-myb Oncogenes in Hematopoiesis and Leukemogenesis ...
Web Search

Bcl-3 expression and nuclear translocation are induced by granulocyte-macrophage colony-stimulating … - Full text - MIT Libraries
MY Zhang, EW Harhaj, L Bell, SC Sun, BA Miller - Blood, 1998 - bloodjournal.org
... Stimulation with GM-CSF enhanced c-myb mRNA expression in these cells. ... Induction
of c-myb mRNA was observed in GM-CSF-stimulated TF-1 cells. ...
Cited by 22 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Arthur Sackler Colloquia Home Help [Feedback][For Subscribers][Archive][Search][Contents] - Full text - MIT Libraries
A Skapenko, J Leipe, U Niesner, K Devriendt, R … - J. Exp. Med, 2004 - pnas.org
... Immunol Home page C. Hernandez-Munain and MS Krangel Distinct Roles for c-Myb and
Core ... Home page Y. Ono, N. Fukuhara, and O. Yoshie TAL1 and LIM-Only Proteins ...
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Erythroblasts from Friend virus infected- and phenylhydrazine-treated mice accurately model … - Full text - MIT Libraries
VM Hodges, PC Winter, TRJ Lappin - British Journal of Haematology, 1999 - blackwell-synergy.com
... The contributions of other transcription factors such as TAL1, Lmo2, c-myb, c-myc,
Id and other MARE binding factors during terminal erythropoiesis in PHZ and ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov

The Vascular Wall as a Source of Stem Cells - Full text - MIT Libraries
M TAVIAN, BO ZHENG, E OBERLIN, M CRISAN, BIN SUN, … - Ann. NY Acad. Sci, 2005 - annalsnyas.org
... with early blood cell progenitors (CD45 + , CD34 ++ , CD31 + , CD43 + , CD44 + ,
CD164 + , CD38 – , Lin-, GATA-2 + , GATA-3 + , c-myb + , SCL/Tal1 + , c-kit ...
Web Search - annalsnyas.org - ncbi.nlm.nih.gov

Multiple negative elements contribute to repression of the HOX 11 proto-oncogene - Full text - MIT Libraries
RL Brake, UR Kees, PM Watt - Oncogene, 1998 - nature.com
... c-Myb is expressed in cells of the haematopoietic lineages (Sullivan et al., 1997 ...
Moreover, expression of the TAL1/SCL proto-oncogene is reported to be deregu ...
Cited by 8 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding … - Full text - MIT Libraries
A Miyamoto, X Cui, L Naumovski, ML Cleary - Mol. Cell. Biol, 1996 - mcb.asm.org
... as there have been no reports of in vivo DNA-binding sites activated by either LYL1
or TAL1. ... Oncogenes c-myb and c-fos contain the consensus LYL1-E12 site. ...
Cited by 22 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Hematopoietic-specific genes are not induced during in vitro differentiation of scl-null embryonic … - Full text - MIT Libraries
AG Elefanty, L Robb, R Birner, CG Begley - Blood, 1997 - bloodjournal.org
... Mice deficient in c-myb had a selective defect in fetal liver hematopoiesis, but
analysis ... W, Amylon M, Smith R, Baer R: Does activation of the TAL1 gene occur ...
Cited by 65 - Web Search - bloodjournal.org - bloodjournal.org - ncbi.nlm.nih.gov - all 5 versions »

Phosphorylation by Mitogen-activated Protein Kinase Mediates the Hypoxia-induced Turnover of the TAL … - Full text - MIT Libraries
T Tang, JL Arbiser, SJ Brandt - J Biol Chem, 2002 - jbc.org
Page 1. Phosphorylation by Mitogen-activated Protein Kinase Mediates the
Hypoxia-induced Turnover of the TAL1/SCL Transcription Factor in Endothelial Cells* ...
Cited by 6 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Locus Control Regions: Description in the LCR-TRRDatabase
OA Podkolodnaya, VG Levitsky, NL Podkolodnyi - MOLECULAR BIOLOGY, 2001 - kluweronline.com
... NF-E2 USF/TAL1 USF J-BP GATA-1 GATA-1 HS2NF CAC USF/TAL1 NF-E2 ... GATA-1, NF-E2, EKLF,
PU.1, Pit-1, Myb, Elf1 Enhancer regions Tissue-specific transcription trans ...
Cited by 1 - Web Search - springerlink.com - Get it from MIT Libraries

Hematopoietic Stem Cell Enrichment From the AGM Region of the Mouse Embryo
C Robin, E Dzierzak - Methods Mol Med, 2005 - biomed.humanapress.com
... CD34 + cells in the clusters express some transcriptional factors (SCL/Tal1,
GATA2 and 3, c-myb; refs. 29,46,48) and also many molecules ...
Web Search - journals.humanapress.com - neurosci.humanapress.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Hematopoietic differentiation of human embryonic stem cells progresses through sequential … - Full text - MIT Libraries
ET Zambidis, B Peault, TS Park, F Bunz, CI Civin - Blood, 2005 - bloodjournal.org
... of MHE colonies and primitive erythroid colonies coincides with a dramatic increase
in expression of SCL/TAL1, GATA1, GATA2, EKLF, PU.1, C-MYB, and CDX4 in day ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Haemangioblast commitment is initiated in the primitive streak of the mouse embryo - Full text - MIT Libraries
TL Huber, V Kouskoff, H Joerg Fehling, J Palis, G … - Nature, 2004 - nature.com
... Trauth, K. & Klempnauer, KH Expression of mouse c-myb during embryonic ... Combinatorial
effects of Flk1 and Tal1 on vascular and hematopoietic development in the ...
Cited by 11 - Web Search - nature.com - ncbi.nlm.nih.gov

Oncogenes et leucemies: historique et perspectives
S Gisselbrecht, BG Roussy - M e decine et Science, 2003 - erudit.org
... Ras, Harvey et Kirsten Ras, des oncogènes nucléaires Myc, Myb, et de ... associées à
des complexes transcriptionnels comme les protéines LYL1, TAL1/SCL, LMO1 ...
Cited by 2 - Cached - Web Search

Manipulation of Mouse Hematopoietic Progenitors by Specific Retroviral Infection - Full text - MIT Libraries
GJ Murphy, B Gottgens, A Vegiopoulos, MJ Sanchez, … - J Biol Chem, 2003 - medsciences.bham.ac.uk
... in the chicken and is likewise dependent on the particular structure of v-Myb. ... of
a hematopoietic progenitor-specific enhancer from the scl (tal1) gene offers ...
Cited by 2 - View as HTML - Web Search - jbc.org - ncbi.nlm.nih.gov

E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause … - Full text - MIT Libraries
DB Sykes, MP Kamps - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... c-kit (SCF receptor), Scl/tal1, IL-7 receptor α, E2A, Ikaros, PU.1, GATA3, and ID2
(Fig. 2). E2a/Pbx1 pro-T-cell proliferations also expressed c-myb and Egr2 ...
Cited by 4 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Increased lymphomagenicity and restored disease specificity of AML1 site (core) mutant SL3-3 murine … - Full text - MIT Libraries
S Ethelberg, J Lovmand, J Schmidt, A Luz, FS … - J. Virol, 1997 - jvi.asm.org
... 28, 53), basic helix-loop-helix (bHLH) factor transcription factors (26, 27), the
glucocorti- coid receptor (GR) (6), and the c-Myb transcription factor (28, ...
Cited by 15 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov

Lysine acetylation and the bromodomain: a new partnership for signaling - Full text - MIT Libraries
XJ Yang - BioEssays, 2004 - doi.wiley.com
... For example, bromodomains of Gcn5, PCAF, TAF1 and CBP are able to recognize
acetyllysine residues in histones, HIV Tat, p53, c-Myb or MyoD. ... (62,63) TAL1/SCL ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

Scl is required for dorsal aorta as well as blood formation in zebrafish embryos - Full text - MIT Libraries
LJ Patterson, M Gering, R Patient - Blood, 2005 - bloodjournal.org
... One gene, expressed in hemangioblast populations, is scl/tal1, hereafter referred
to as scl ... Runx1-depletion in zebrafish results in the loss of c-myb and ikaros ...
Web Search - bloodjournal.org - ncbi.nlm.nih.gov

CBP and p300: versatile coregulators with important roles in hematopoietic gene expression
GA Blobel - J Leukoc Biol, 2002 - jleukbio.org
... transcription factors that interact with CBP (including the AML, C/EBP, E2A,
GATA-2, GATA-3, Myb, and Ets ... The latter include GATA-1, NF-E2, EKLF, and SCL/TAL1. ...
Cited by 11 - Web Search - ncbi.nlm.nih.gov - virologyj.com - Get it from MIT Libraries

Characterization of Interactions between Transcription Factors and a Regulatory Region Spanning nt …
LA Pereira, MJ Churchill, AG Elefanty, T Gouskos, … - Journal of Biomedical Science, 2002 - content.karger.com
... Key Words HIV-1 LTR promoter W c-Myb W Basic helix-loop-helix W ... The LTR 9 Myb –
oligonucleotide was unable to bind recombi- nant c-Myb (data not shown). ...
Cited by 4 - Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
J Barata, A Cardoso, V Boussiotis - Leukemia & Lymphoma, 2005 - dx.doi.org
... differentiation, erythropoietin induces phosphoryla- tion of TAL1 [6], and TAL1
levels are ... Interestingly, IL-7 regulates the expression of c-myb in cutaneous T ...
Web Search - taylorandfrancis.metapress.com

acquises de la cellule souche hematopoietique ou d’un precurseur deja commis vers les lignees …
S YNTHESE - MEDECINE/SCIENCES, 2003 - ist.inserm.fr
... Ras, Harvey et Kirsten Ras, des oncogènes nucléaires Myc, Myb, et de ... associées à
des complexes transcriptionnels comme les protéines LYL1, TAL1/SCL, LMO1 ...
View as HTML - Web Search - erudit.org

GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES … - Full text - MIT Libraries
N Suwabe, S Takahashi, T Nakano, M Yamamoto - Blood, 1998 - bloodjournal.org
... Transcription factors expressed in erythroid cells include GATA-1, GATA-2, NF-E2,
AML1, EKLF, Myb, PU1, rbtn2, and SCL/tal-1. 4-12 These transcription factors ...
Cited by 34 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Chromosomal abnormalities and tumor development: from genes to therapeutic mechanisms - Full text - MIT Libraries
C Cobaleda, J Perez-Losada, I Sanchez-Garcia - BioEssays, 1998 - doi.wiley.com
... Many other translocations and inversions result in gene activation in lymphoid
malignancies. (6,7) The TAL1/SCL gene is one important example. ...
Cited by 13 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Increased expression of the distal, but not of the proximal, Gata 1 transcripts during … - Full text - MIT Libraries
AM Vannucchi, S Linari, CS Lin, MJ Koury, MC … - Journal of Cellular Physiology, 1999 - doi.wiley.com
... in the expression of Eklf, Scl, and Nfe2, three genes required for erythroid
differentiation, and preceded by 24 h the repression of Gata2 and Myb expression. ...
Cited by 9 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is … - Full text - MIT Libraries
M Centola, G Wood, DM Frucht, J Galon, M Aringer, … - Blood, 2000 - bloodjournal.org
... factors shown to mediate myelomonocytic-specific expression, including AML (acute
myelogenous leukemia), c-Myb, MZF (myeloid zinc finger), and TAL1, were also ...
Cited by 53 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov