… –helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities - Full text - MIT Libraries
D Kim, M Xu, L Nie, XC Peng, E Jimi, RE Voll, T … - Immunity, 2002 - ingentaconnect.com
... Regulate Pre-TCR and TCR Signaling through Modulation of Rel/NF- B ... their activities
through transgenic overexpression of their inhibitors Id1 and Tal1 leads to ...
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Measurement of SIL–TAL1 fusion gene transcripts associated with human T-cell lymphocytic leukemia …
JD Curry, MT Smith - Leukemia Research, 2003 - ehscenter.berkeley.edu
... While the use of plasmid DNA to generate curves has rel- evance when solely ... adult
lymphocyte populations yielded no expres- sion of the SIL–TAL1 fusion gene. ...
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Molecular analysis of 1p32 genetic involvement in pediatric T-cell non-Hodgkin's lymphoma - Full text - MIT Libraries
D Perotti, F Pettenella, R Luksch, R Giardini, F … - Haematologica, 1999 - haematologica.it
... REL: relapse; M-mass: mediastinic mass; EX: dead; MB: bone marrow; PRO ... Discussion
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helix-loop-helix protein - Full text - MIT Libraries
HAIL Hsu, I WADMAN, JT TSAN, R BAER - Biochemistry, 1994 - pnas.org
... Positive and negative transcriptional control by the TAL1 helix-loop-helix protein ...
tranriptional activity (ie, TAL1-E47 heterodimers). How- ...
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Rules discovery in fuzzy relational databases
JC Cubero, O Pons, JM Medina, M Vila - The 3 rd International Symposium on Uncertainty Modeling and …, 1995 - doi.ieeecomputersociety.org
... r2 = F&(r), and the other one 1 = F;(r) where Z = REL - Y), in such a ... f(tal1) = 85
V heavy = heavy is consistent with these impositions and definition of fuzzy ...
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[BOOK] The Oncogene handbook
R Hesketh - 1994 - Academic Press
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NF-kappa B transcription factors are involved in normal erythropoiesis - Full text - MIT Libraries
MY Zhang, SC Sun, L Bell, BA Miller - Blood, 1998 - bloodjournal.org
... To identify potential target genes of NF- B/Rel proteins found in normal ... proliferation
and differentiation include GATA-1, 34 SCL (or TAL1), and other basic ...
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Transaldolase B of Escherichia coli K-12: Cloning of its gene, talB, and characterization of the … - Full text - MIT Libraries
GA Sprenger, U Schoerken, G Sprenger, H Sahm - Journal of Bacteriology, 1995 - jb.asm.org
... at a high apparent K m (>2 M) and with a V rel of 12 ... which showed significant amino
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A multiplex reverse transcription-polymerase chain reaction strategy for the diagnostic molecular … - Full text - MIT Libraries
L Elia, M Mancini, L Moleti, G Meloni, S Buffolino … - Haematologica-, 2003 - haematologica.org
... SIL/TAL1 3 − − − − − 3 ... What is already known on this topic Molecular
characterization of leukemic cells is rel- evant to clinical decision making in ...
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The use of genetic microarray analysis to classify and predict prognosis in haematological … - Full text - MIT Libraries
AP Levene, GJ Morgan, FE Davies - Clinical and Laboratory Haematology, 2003 - blackwell-synergy.com
... had a favourable prognosis (5-year survival 92%), compared with the TAL1 + and LYL1 ...
BCL-2 gene, and chromosome 2p amplifications involving the c-REL gene only ...
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IkBa/IkBe deficiency reveals that a critical NF-kB dosage is required for lymphocyte survival - Full text - MIT Libraries
B Goudeau, F Huetz, S Samson, JP Di Santo, A … - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... apoptosis of T cells at the DP stage in Id1 and Tal1 transgenic mice ... Multiple studies
with various mutant mice, p65(RelA) -/- c-Rel -/- (34), IKKb -/- (35, 36 ...
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Bcl-3 expression and nuclear translocation are induced by granulocyte-macrophage colony-stimulating … - Full text - MIT Libraries
MY Zhang, EW Harhaj, L Bell, SC Sun, BA Miller - Blood, 1998 - bloodjournal.org
... NF- B/Rel designates a widely distributed family of transcription factors that modulate
the expression of genes involved in immune and acute-phase responses as ...
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Notch signaling in leukemia
JC Aster, WS Pear - Curr. Opin. Hematol, 2001 - co-hematology.com
... Moreover, misexpression of TAL1, LMO1, or LMO2, the genes most commonly dysregulated ...
Rel-type transcription factors represent a second potential target for the ...
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Physical interaction of the bHLH LYL 1 protein and NF-κB 1 p 105 - Full text - MIT Libraries
R Ferrier, R Nougarede, S Doucet, B Kahn-Perles, J … - Oncogene, 1999 - nature.com
... among both the bHLH family and the NF- B/Rel family. Notably, we did not observe
significant interaction between p105 and the two LYL1-related TAL1 and TAL2 ...
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Molecular and Genetic Mechanisms of Lymphomagenesis
R Kušec - cmj.hr
... Hprt gene have little conse- quence and are found at low frequency in normal T cells,
whereas the deletions in the TAL1 and MTS1 ... REL 2p13 gene amplification ...
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Stem cell leukaemia gene and its role in normal and leukaemic haematopoiesis
CG Begley - haematologica.org
... The mechanisms by which SCL is controlled are rel- atively poorly understood. ... ization
between Lmo2 (Rbtn2) and Tal1 alters thy- mocyte development and ...
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Transcriptional Control of T Lymphocyte Differentiation - Full text - MIT Libraries
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - Stem Cells, 2001 - stemcells.alphamedpress.org
... of the endogenous TCRA enhancer could be inhibited by the class II bHLH factor TAL1
[69 ... identified in the Il2 minimal promoter such as the NF- B/Rel factors and ...
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Chromosomal abnormalities and tumor development: from genes to therapeutic mechanisms - Full text - MIT Libraries
C Cobaleda, J Perez-Losada, I Sanchez-Garcia - BioEssays, 1998 - doi.wiley.com
... MYC, BTG t(7;19)(q35;p13) T-ALL TCR- , LYL1 t(1;14)(p32;q11) T-ALL TAL1/SCL, TCR ...
CAN t(4;16)(q26;p13) T lymphoma IL-2, BCM inv(2;2)(p13;p11–14) NHL REL/NGR inv ...
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New Molecular Methods for Classification, Diagnosis and Therapy Prediction of Hematological … - Full text - MIT Libraries
A Zvara, L Hackler Jr, BZ Nagy, T Micsik, LG … - Pathol. Oncol. Res, 2002 - webio.hu
... encoding for transcription factors (LYL1, HOX11, HOX11L2, TAL1), their abnormal ...
fluorescent antibodies, the direct visualization of the rel- ative position of ...
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Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute …
JJ van Dongen, EA Macintyre, JA Gabert, E … - Leukemia, 1999 - nature.com
... RARA , inv (16) with CBFB-MYH11 , and microdeletion 1p32 with SIL-TAL1 . ...
del(1)(p32;p32) SIL-TAL1 CEM,RPMI8402 + EA Macintyre et al JJM van Dongen et al ...
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TRANSCRIPTION FACTORS
OFB CELLS - doi.wiley.com
... 31 Yulia Kaluzhny, Mortimer Poncz, and Katya Ravid 4 Role of TAL1/SCL Transcription
Factor in Normal and Leukemic Hematopoiesis 51 Stephen J. Brandt ...
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S tem C ells
FJT Staal, F Weerkamp, AW Langerak, RW Hendriks, … - immuneweb.xxmc.edu.cn
... MyoD, Myf 5, MASH, HASH, TAL1, as-c Class III bHLH-zip proteins ... These include a
microdeletion on chromosome 1p32 harboring the TAL1 or SCL gene [51], and transl
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Molecular diagnosis of lymphoid malignancies by gene expression profiling
RE Davis, LM Staudt - Curr. Opin. Hematol, 2002 - co-hematology.com
... Amplification of the c-rel locus of chromosome 2p is another recurrent abnormality ...
expression levels of certain known T-ALL oncogenes (Hox11, Tal1, Lyl1) were ...
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Molecular diagnosis and monitoring of acute lymphoblastic leukaemia: applications and limitations
A Biondi, G Cazzaniga - haematologica.it
... translocations oc- curring in leukaemia has emerged as one the most rel- evant issue ...
PML-RAR , inv(16) with CBFB-MYH11, and mi- crodeletion 1p32 with SIL-TAL1. ...
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Contribution of immunophenotypic and genotypic analyses to the diagnosis of acute leukemia
R Stasi, CG Taylor, A Venditti, GD Poeta, JM … - Annals of Hematology, 1995 - springerlink.com
... of these techniques it has become apparent that a proportion of leukemias exhibit
the biologically rel- ... or L2/T and T-precursor ALL t (1;3) (p12;p21) TAL1-Xb 2 ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Restoring Adshh stricta to Pbms pahstris Ecosystems, on the Atlantic; Coasti Phin, USA
KW Outd, ME Wi&uns, O Onokpise - srs.fs.fed.us
... an average of eight leaves per plug and were 4 cm tal1 one week ... wiregrass plants
died during the second growmg season but survival was rel- atively constant on ...
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Reduced Widths of Individual Nuclear Energy Levels - Full text - MIT Libraries
AM Lane - Reviews of Modern Physics, 1960 - link.aps.org
... 0.0L - -*-SPECTRUM OF - /REL.5DUAL NUCLEUS rj tAl1 z bi z 0 -A . J z "I'. - - i__ -
INCREA5IN q L)XCITATION OFt RESIDUAL NUCLEU5 / _- / 1 --- . (i) I 527 (ii ...
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Genomic approaches to hematologic malignancies - Full text - MIT Libraries
BL Ebert, TR Golub - Blood, 2004 - bloodjournal.org
... expression patterns revealed dysregulated expression of the key oncogenes HOX11,
TAL1 (SCL), LYL1 ... present in 26 cases, and amplification of the c-rel gene was ...
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Supplementary Data ‘Stemness’: Transcriptional Profiling of Embryonic and Adult Stem Cells
M Ramalho-Santos, S Yoon, Y Matsuzaki, RC Mulligan … - intl.sciencemag.org
... markers Kit, Cd34, Abcg2, Mpl, Tie1, Tie2/Tek, Vla5, Flp, Tal1/Scl, Pu.1 and
Gata2. Detection of Cd34 is consistent ... Flp or Tal1/Scl). This ...
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DERIVATION FONCTIONNELLE ABSTRAITE Jacques Gapaillard
JT SCHWARTZ - manuscripta math, 1974 - springerlink.com
... dl, __de • et tout rel , 0 < e < 1 , il existe un fs , tel ... (I]) Dans les mmes conditions
qu'en (I0) il existe un f 6 et un rel I > 0 tels que 360 ...
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Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative … - Full text - MIT Libraries
GL Condorelli, A Tocci, R Botta, F Facchiano, U … - Mol Cell Biol, 1997 - mcb.asm.org
... dI- dC), and 1 to 3 pmol of a 32 P-labeled, double-stranded oligonucleotide probe
containing the preferred sequence for DNA binding by TAL1/E2A heterodimers ...
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CL-46, a novel collectin highly expressed in bovine thymus and liver - Full text - MIT Libraries
S Hansen, D Holm, V Moeller, L Vitved, C Bendixen, … - J. Immunol, 2002 - jimmunol.org
... found (26, 27). We also identified potential sites for NF- B, c-Rel, and
the gut-enriched Krueppel-like factor (28, 29). Besides the ...
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Cloning and characterization of the proximal murine Phex promoter - Full text - MIT Libraries
S Liu, R Guo, LD Quarles - Endocrinology, 2001 - endo.endojournals.org
... C, Ruben SM, Rosen CA 1992 Selection of optimal B/Rel DNA-binding motifs ... molecule
assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA ...
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Studies of the Ribosomal Protein S19 in Erythropoiesis
H MATSSON - publications.uu.se
... erythroid devel- opment is regulated by several transcription factors including
TAL1, LMO2 and ... of a putative site for the transcription factors c-Rel and Rel-a ...
Web Search - diva-portal.org

Clonogenicity, gene expression and phenotype during neutrophil versus erythroid differentiation of … - Full text - MIT Libraries
L Edvardsson, J Dykes, ML Olsson, T Olofsson - British Journal of Haematology, 2004 - ask.lub.lu.se
... proteinase 3) Hs 00160521_m1 SPI1 PU.1 Hs 00231368_m1 TAL1 SCL/Tal1 Hs 00268434_m1
18S ... The graphs show n-fold differences in gene expression rel- ative to CD34 ...
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A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic … - Full text - MIT Libraries
BJ Feldman, T Hampton, ML Cleary… - Blood, 2000 - bloodjournal.org
... Recent studies have shown that Rel/NF- B triggers Notch pathway signaling by inducing ...
Wadman I, Baer R. Formation of in vivo complexes between the TAL1 and E2A ...
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Acute Lymphoblastic Leukemia - Full text - MIT Libraries
D Hoelzer, N Gokbuget, O Ottmann, CH Pui, MV … - Hematology, 2002 - asheducationbook.org
Page 1. 162 American Society of Hematology Acute Lymphoblastic Leukemia
Dieter Hoelzer, Nicola Gökbuget, Oliver Ottmann, Ching-Hon ...
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Eukaryotic gene regulation: a flew over the transcription factor nest
P Ziros, AG Papavassiliou - mednet.gr
... which, in addition, bear a LZIP motif) and in the factors Tal1, Tal2 and Lyl1 ... contained
in certain proto-on- coproteins such as Elk-1. •the Rel homology domain ...
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An Empirical Evaluation of Simple DTD-Conscious Compression Techniques
J Cheney - homepages.inf.ed.ac.uk
... log excerpt) exhibit substantial improvements of 16– 35%, and large, highly-structured
files (elts, periodic table data; pcc1-3, formal proofs; tal1-3, typed ...
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The roles of Bcl-X (L) and apopain in the control of erythropoiesis by erythropoietin - Full text - MIT Libraries
PA Gregoli, MC Bondurant - Blood, 1997 - bloodjournal.org
... analyzed such as EP receptor, actin, 8 GATA1, EKLF (MCB, unpublished observations),
and SCL/TAL1. ... family that includes ICE, Ich-1/Nedd-2, Ich-2/TX/Rel II, Ich-2 ...
Cited by 75 - Web Search - bloodjournal.org - ncbi.nlm.nih.gov

Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted … - Full text - MIT Libraries
X Ma, T Husain, H Peng, S Lin, O Mironenko, N Maun … - Blood, 2002 - bloodjournal.org
... Sox5 SRY-box containing gene 5 — 3.1 0.22 Tal1 T-cell acute lymphocytic leukemia
1 — — Xbp1 Essential for plasma cell differentiation, liver development ...
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Dynamic spatiotemporal expression of LIM genes and cofactors in the embryonic and postnatal cerebral … - Full text - MIT Libraries
S Bulchand, L Subramanian, S Tole - Developmental Dynamics, 2003 - doi.wiley.com
... of Ap de- pends on the formation of a tet- rameric complex comprising an Ap dimer
bridged by a CHIP dimer, a process that is regulated by the rel- ative levels ...
Cited by 10 - Web Search - ncbi.nlm.nih.gov

CONSEQUENCES OF CHROMOSOMAL ABNORMALITIES IN TUMOR DEVELOPMENT - Full text - MIT Libraries
I Sanchez-Garcia - Annual Review of Genetics, 1997 - dx.doi.org
... Many other translocations and inversions result in gene activation in lymphoid
malignancies (Table 1a ). The TAL1/SCL gene is an important example. ...
Cited by 25 - Web Search - wwwlib.bionet.nsc.ru - genet.annualreviews.org - ncbi.nlm.nih.gov - all 6 versions »

Protein interaction cloning in yeast: Identification of mammalian proteins that react with the … - Full text - MIT Libraries
PM Chevray, D Nathans - Proc. Nat. Acad. Sci, 1992 - pnas.org
PDF Version of this Article. Similar articles found in: PNAS Online PubMed. PubMed
Citation. This Article has been cited by: other online articles. ...
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Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
J Barata, A Cardoso, V Boussiotis - Leukemia & Lymphoma, 2005 - dx.doi.org
... frequent in T-ALL [4], and lead to the abnormal activation of several transcription
factor genes, including members of the bHLH (MYC, TAL1, TAL2, LYL1, BHLHB1 ...
Web Search - taylorandfrancis.metapress.com

Hyperresponse to T-Cell Receptor Signaling and Apoptosis of Id1 Transgenic Thymocytes - Full text - MIT Libraries
Z Qi, XH Sun - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... 1995. Does activation of the TAL1 gene occur in a majority of patients with T-cell
acute ... It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation ...
Web Search - mcb.asm.org - ncbi.nlm.nih.gov

F1EPCflEKThBbI PA3BI1TI1 TEJ1EKOMMYH1KALLL1I1
I Baeqeiuie, R Amplification - ieeexplore.ieee.org
... eicrypy ceTeh [21. J1M6a-KoMMy1-aqiicl pacwtipcie napary KOMMy-
TaL1’1I.I Ha OCHOB MBTOK H8 OflTII4BCKYIO o6nacm. 3/ecb POflb ...
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Peculiarities of Organization and Functioning of the Fish Red Blood System
AA Soldatov - JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY, 2005 - springerlink.com
... have been shown to occur under control of transcription factor SCL/Tal1 [53]. ... The
technique developed on this basis has allowed assessing a rel ative level of ...
Web Search

Embryonic stem cells and transgenic mice in the study of hematopoiesis
SH Orkin - Int. J. Dev. Biol, 1998 - ijdb.ehu.es
... approaches enriches our understanding of the biological rel- evance and ... Protein
dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and ...
Cited by 29 - View as HTML - Web Search - ijdb.ehu.es - ncbi.nlm.nih.gov - Get it from MIT Libraries

Lysine acetylation and the bromodomain: a new partnership for signaling - Full text - MIT Libraries
XJ Yang - BioEssays, 2004 - doi.wiley.com
... K321, 327, 331 p300 Promote apoptosis ( 52) NF- k B p65/Rel A K218, 221 p300 HDAC3 ...
p300/CBP association and transcription (62,63) TAL1/SCL K221 and/or 222 PCAF ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov