Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast … - Full text - MIT Libraries
WM Yang, C Inouye, Y Zeng, D Bearss, E Seto - Proc. Natl. Acad. Sci. USA, 1996 - dx.doi.org
... Biochemistry. Transcriptional repression by YY1 is mediated by interaction
with a mammalian homolog of the yeast global regulator RPD3. ...
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mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or … - Full text - MIT Libraries
S Huang, SJ Brandt - Mol Cell Biol, 2000 - mcb.asm.org
... All rights reserved. mSin3A Regulates Murine Erythroleukemia Cell Differentiation
through Association with the TAL1 (or SCL) Transcription Factor. ...
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Conserved E Boxes Function as Part of the Enhancer in Hypersensitive Site 2 of the beta-Globin Locus … - Full text - MIT Libraries
L Elnitski, W Miller, R Hardison - J. Biol. Chem, 2004 - jbc.org
... The TAL1 binding site probe contains the optimal binding site for a TAL1-E47
heterodimer (37). The YY1 binding site is from the P5 promoter of adeno-associated ...
Cited by 33 - Web Search - jbc.org - ncbi.nlm.nih.gov

Transcriptional control of globin gene switching during vertebrate development
MH Baron - Biochim Biophys Acta, 1997 - immuneweb.xxmc.edu.cn
... family, which Ž . recognize CACCC motifs Table 1 and include the ubiquitous
proteins Sp1 and YY1, erythroid Ž . Kruppel-like factor ...
Cited by 22 - View as HTML - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Acetylation of the BETA2 transcription factor by PCAF is important in Insulin gene expression
NIH NCI, NIH NIDDK - jbc.org
... factors (p53 (44, 54), HIV Tat (61, 62), E2F (56), TAL1 (57), YY1 (63)) but not
all (GATA-1 (43, 64) and EKLF (65, 66), p300 only; MyoD (58), PCAF only). ...
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Identity of the beta-Globin Locus Control Region Binding Protein HS 2 NF 5 as the Mammalian Homolog … - Full text - MIT Libraries
LT Lam, EH Bresnick - J Biol Chem, 1998 - jbc.org
... 27), GATA-1 (28, 29), TAL-1 (30), USF (20, 31), SP1 (32), YY1 (33), and ... conserved
region of HS2 containing an E box (34), which was a putative TAL1-binding site ...
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Acetylation and modulation of erythroid Krueppel-like factor (EKLF) activity by interaction with … - Full text - MIT Libraries
W Zhang, JJ Bieker - Biochemistry, 1998 - dx.doi.org
... Home page, J. Biol. Chem. Home page CY Wang, YJ Liang, YS Lin, HM Shih, YS
Jou, and WCY Yu YY1AP, A Novel Co-activator of YY1 J. Biol. ...
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A novel DNA-binding protein, HS 2 NF 5, interacts with a functionally important sequence of the … - Full text - MIT Libraries
LT Lam, EH Bresnick - J Biol Chem, 1996 - jbc.org
... Although no evidence for TAL1 binding was observed, a previously unreported DNA ... that
binds multiple proteins; NF-E2, GATA-1, USF, and YY1, known transcription ...
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Locus Control Regions: Description in the LCR-TRRDatabase
OA Podkolodnaya, VG Levitsky, NL Podkolodnyi - MOLECULAR BIOLOGY, 2001 - kluweronline.com
... NF-E2 USF/TAL1 USF J-BP GATA-1 GATA-1 HS2NF CAC USF/TAL1 NF-E2 ... HBP1, LEF-1/TCF-1,
SOX4, Bach1/MafK, USF, NF-E2, YY1 Enhancer and chromatin-opening re- gions ...
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SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain … - Full text - MIT Libraries
S Herblot, AM Steff, P Hugo, PD Aplan, T Hoang - Nat Immunol, 2000 - nature.com
... to be controlled primarily by an upstream genomic region that contains three E boxes
together with a number of binding sites for other factors (YY1, ZBP-89, SP1 ...
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Requirements for utilization of CREB binding protein by hypersensitive site two of the ß-globin … - Full text - MIT Libraries
KD Johnson, JE Norton, EH Bresnick - Nucleic Acids Research, 2002 - nar.oupjournals.org
... binding sites for C-promoter binding factor 1 (29) and TAL1 (27); GATA-1 ... 1; E,
E-box; USF, binding site for the upstream stimulatory factor; YY1, binding site ...
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Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells - Full text - MIT Libraries
H Ohta, A Sawada, JY Kim, S Tokimasa, S Nishiguchi … - J Exp Med, 2002 - jem.org
... HDAC may constitute the repressive domain, while zeste and YY1 the DNA binding domain
(12, 13, 16, 17 ... c-erbA , c-Mpl, c-jun, c-fos, c-myc, c-myb, tal1/SCL, AML1 ...
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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid … - Full text - MIT Libraries
GA Blobel, T Nakajima, R Eckner, M Montminy, SH … - Biochemistry, 1998 - dx.doi.org
... Chem. Home page SS Bhalla, L. Robitaille, and M. Nemer Cooperative Activation by
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The use of genetic microarray analysis to classify and predict prognosis in haematological … - Full text - MIT Libraries
AP Levene, GJ Morgan, FE Davies - Clinical and Laboratory Haematology, 2003 - blackwell-synergy.com
... a favourable prognosis (5-year survival 92%), compared with the TAL1 + and LYL1 ... RSK1,
defender against cell death 1 (DAD1), and the transcription factor YY1. ...
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Transcriptional Regulation of the Stem Cell Leukemia Gene(SCL)--- Comparative Analysis of Five … - Full text - MIT Libraries
B Gottgens, LM Barton, MA Chapman, AM Sinclair, B … - Genome Research, 2002 - genome.org
... The SCL gene (also known as Tal1) encodes a basic helix-loop-helix (bHLH ... B) Alignment
of the conserved sequences in exon 1. The conserved YY1 site is indicated. ...
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Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2 … - Full text - MIT Libraries
Y Qiu, M Guo, S Huang, R Stein - Mol Cell Biol, 2002 - mcb.asm.org
... p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein. ... Relief
of YY1 transcriptional repression by adenovirus E1A is mediated by E1A ...
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The NFY transcription factor functions as a repressor and activator of the von Willebrand factor … - Full text - MIT Libraries
Y Peng, N Jahroudi - Blood, 2002 - bloodjournal.org
... We have also used oligonucleotides that contain Tal1 and Oct binding consensus
sequences ... The transcription factor YY1 can function as either an activator or a ...
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Histone Acetylation/Deacetylation and Cancer: An “Open” and “Shut” Case?
G SG, BT Teh - Current Molecular Medicine, 2001 - ingentaconnect.com
... p53 [35-38,551] Rch 1 [547] Sp1 [552] Taf I 68 [553] Tal1/SCL [554 ... HDAC2 was also
found to associate with the mammalian zinc finger transcription factor YY1 [157 ...
Cited by 14 - Web Search - hagedorn.dk - ncbi.nlm.nih.gov - Get it from MIT Libraries

Chromatin immunoselection defines a TAL-1 target gene - Full text - MIT Libraries
S Cohen-Kaminsky, L Maouche-Chretien, L Vitelli, … - The EMBO Journal, 1998 - embojournal.npgjournals.com
... Text] . Baer, R. (1993) TAL1, TAL2 and LYL1: a family of basic helix-loop-
helix proteins implicated in T cell acute leukaemia. Semin. ...
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CLINICAL DEVELOPMENT OF HISTONE DEACETYLASE INHIBITORS AS ANTICANCER AGENTS* - Full text - MIT Libraries
DC Drummond, CO Noble, DB Kirpotin, Z Guo, GK … - Annual Review of Pharmacology and Toxicology, 2005 - arjournals.annualreviews.org
... (160) Sp3 Transcriptional activator or repressor (161) TAL1 Regulator of normal
and leukemic hematopoiesis (162) YY1 Multifunction transcription factor (163) ...
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Unanticipated repression function linked to erythroid Krueppel-like factor - Full text - MIT Libraries
X Chen, JJ Bieker - Mol Cell Biol, 2001 - mcb.asm.org
... Positive and negative transcriptional control by the TAL1 helix-loop-helix protein. ...
GATA1 and YY1 are developmental repressors of the human epsilon-globin gene ...
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The leukaemia-associated transcription factors EVI-1 and MDS 1/EVI 1 repress transcription and … - Full text - MIT Libraries
U Vinatzer, J Taplick, C Seiser, C Fonatsch, R … - British Journal of Haematology, 2001 - blackwell-synergy.com
... A number of these leukaemogenic factors, eg PML-RAR , PLZF-RAR , AML-ETO, AML-TEL,
or TAL1 have been shown to functionally associate with HDACs ( Grignani et al ...
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Identification and characterization of Grainyhead-like epithelial transactivator(GET-1), a novel … - Full text - MIT Libraries
EI Kudryavtseva, TM Sugihara, N Wang, RJ Lasso, JF … - Developmental Dynamics, 2003 - doi.wiley.com
... on context, repress transcription and was shown to co- operate with YY1 to repress ...
1. In erythroid cells, LMO-2 interacts with the E-box bind- ing TAL1/SCL-E12 ...
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Lysine acetylation and the bromodomain: a new partnership for signaling - Full text - MIT Libraries
XJ Yang - BioEssays, 2004 - doi.wiley.com
... p300/CBP association and transcription (62,63) TAL1/SCL K221 and/or 222 PCAF Stimulate ...
CBP Stimulate transcription (81) YY1 p300, PCAF HDAC1 Increase HDAC ...
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A role for histone deacetylase activity in HDAC1-mediated transcriptional repression - Full text - MIT Libraries
CA Hassig, JK Tong, TC Fleischer, T Owa, PG Grable … - Biochemistry, 1998 - dx.doi.org
... Home page, Mol. Cell. Biol. Home page YL Yao, WM Yang, and E. Seto Regulation of
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Promoter 1 of LMO2, a master gene for hematopoiesis, is regulated by the erythroid specific …
HH Anthropology, M Genetics, G Berlin - Gene Funct. Dis, 2000 - doi.wiley.com
... [11], which is a binding site for a DNA binding complex including TAL1,
E47, GATA1, LDB1/NL1 and LMO2 found in erythroid cells. ...
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The function of the bcl-x promoter in erythroid progenitor cells - Full text - MIT Libraries
C Tian, P Gregoli, M Bondurant - Blood, 2003 - bloodjournal.org
... AP-2 (all isoforms), Brn-3 , PU-1, GATA-1, YY1, PPAR- , PPAR ... bearing a binding sequence
for the transcription factor TAL1 (5'-CTCCCAGCAGCTGGCCTAGGAGATAGCAGCAG-3 ...
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Identification of Id2 as a globin regulatory protein by representational difference analysis of K562 … - Full text - MIT Libraries
ML Holmes, JD HALEY, L CERRUTI, WL Zhou, H Zogos, … - Mol. Cell. Biol, 1999 - mcb.asm.org
... binding motifs for a variety of ubiquitous (Sp1, USF, YY1, and others ... Coordinate
expression and developmental role of Id2 protein and TAL1/E2A heterodimer in ...
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LONG-SHENG CHANG
P DATA, S LICENSE - ibgp.org
... Identification of A TAL1 Target Gene Reveals a Requirement for Ldb1 Dimerization
in ... of Large Quantity of Growth Regulatory Proteins, RB, p53, YY1, and Pol δ ...
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Eukaryotic promoter recognition - Full text - MIT Libraries
JW Fickett, AG Hatzigeorgiou - Genome Res, 1997 - genome.org
... Some of these seem to be capable of directing the initiation of transcription even
in the absence of TBP (eg, YY1; cf. Usheva and Schenk 1994). Javahery et al. ...
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Methylation of histone H4 by arginine methyltransferase PRMT1 is essential in vivo for many … - Full text - MIT Libraries
S Huang, M Litt, G Felsenfeld - GENES & DEVELOPMENT, 2005 - genesdev.org
... 2001 ), transcription factor YY1 (Rezai-Zadeh et al. ... mediated acetylation regulates
the function of the basic helix–loop–helix transcription factor TAL1/SCL ...
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LEADING ARTICLE THE REGULATION OF b GLOBIN GENE EXPRESSION AND
PJ Ho - Pathology, 1999 - dx.doi.org
... a distal promoter containing binding sites for the negative regulator YY1 27 and ...
that a large DNA-binding complex in erythroid cells comprising tal1, lmo2, GATA ...
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Bcl-x promoter function in erythroid progenitor cells - Full text - MIT Libraries
C Tian, P Gregoli, M Bondurant, TN Nashville, M … - Blood, 2003 - bloodjournal.org
... the above labeled oligonucleotides: AP-2 (all isoforms), Brn-3α, PU-1,
GATA-1, YY1, PPAR α, γ and δ, E47 and SP1. None of the ...
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E2A and HEB activate the pre-TCR alpha promoter during immature T cell development - Full text - MIT Libraries
A Takeuchi, S Yamasaki, K Takase, F Nakatsu, H … - J. Immunol, 2001 - jimmunol.org
... E, E-box; S, Sp1; Y, YY1; I, Ikaros; G, GATA-1/2. ... 1998. Helix-loop-helix (E2–5, HEB,
TAL1 and Id1) protein interaction with the TCR enhancers. Int. Immunol. ...
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LEADING ARTICLE THE REGULATION OF b GLOBIN GENE EXPRESSION AND
PJ Ho - Pathology, 1999 - taylorandfrancis.metapress.com
... a distal promoter containing binding sites for the negative regulator YY1 27 and ...
that a large DNA-binding complex in erythroid cells comprising tal1, lmo2, GATA ...
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Increased Induction of Osteopetrosis, but Unaltered Lymphomagenicity, by Murine Leukemia Virus SL3-3 … - Full text - MIT Libraries
S Ethelberg, BD Tzschaschel, A Luz, SJ Diaz-Cano, … - J. Virol, 1999 - jvi.asm.org
... human p53 promoter by alternatively binding to a composite element, and YY1 and
E1A ... E-box sequence and context-dependent TAL1/SCL modulation of basic helix-loop ...
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E2A and HEB Activate the Pre-TCR Promoter During Immature T Cell Development
A Takeuchi, S Yamasaki, K Takase, F Nakatsu, H … - jimmunol.org
... E, E-box; S, Sp1; Y, YY1; I, Ikaros; G, GATA-1/2. 2159 ... 1998. Helix-loop-helix
(E2–5, HEB, TAL1 and Id1) protein interaction with the TCR enhancers. Int. ...
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The pathologist’s view point. Part II–aggressive lymphomas - Full text - MIT Libraries
SA Pileri, S Ascani, E Sabattini, G Fraternali- … - Haematologica, 2000 - haematologica.it
... γ T-cell receptor (TCR) genes (at bands 14q11 and 7q34, respectively) and on the
other partners encoding for transcription factors (eg MYC, TAL1, RBTN1, RBTN2 ...
Cited by 11 - View as HTML - Web Search - haematologica.org - haematologica.org - ncbi.nlm.nih.gov - all 9 versions »

Differential Regulation of Hand1 Homodimer and Hand1-E12 Heterodimer Activity by the Cofactor FHL2 - Full text - MIT Libraries
AA Hill, PR Riley - Mol. Cell. Biol, 2004 - mcb.asm.org
... LMO1 (RBTN1) and LMO2 (RBTN2), LIM domain proto-oncogenes activated in T-cell leukemia,
interact with the bHLH factor SCL/TAL1 during erythroid development (54 ...
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Novel strategies in cancer therapeutics: targeting enzymes involved in cell cycle regulation and …
MC Liu, JL Marshall, RG Pestell - Current Cancer Drug Targets, 2004 - ingentaconnect.com
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$45.00+.00 © 2004 Bentham Science Publishers Ltd. Novel Strategies ...
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Molecular organization, expression and chromosomal localization of the mouse pronapsin gene - Full text - MIT Libraries
PJ Tatnell, M Cook, C Peters, J Kay - European Journal of Biochemistry, 2000 - content.febsjournal.org
... assembling an erythroid, DNA-binding complex which includes the TAL1, E47,
GATA-1 ... J., Sissons, JGP & Sinclair, JH (1994) The transcription factor YY1 binds ...
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A novel E 2 box-GATA element modulates Cdc 6 transcription during human cells polyploidization - Full text - MIT Libraries
N Vilaboa, R Bermejo, P Martinez, R Bornstein, C … - Nucleic Acids Research, 2004 - nar.oupjournals.org
... The formation of a multimeric complex formed by GATA-1, Tal1, E47, Lmo2 and Ldb1A
seems to rely on a specific spacing of 8–10 bp ( 1 helix turn) between the ...
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The 11 Conference on Hemoglobin Switching th
B Embryogenesis - scripps.edu
... Interestingly, the Krüppel-like factor YY1 modulates gene expression by interacting
with CREB-binding protein (CBP), a large coactivator molecule with histone ...
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Site-specific Acetylation of the Fetal Globin Activator NF-E 4 Prevents Its Ubiquitination and … - Full text - MIT Libraries
Q Zhao, H Cumming, L Cerruti, JM Cunningham, SM … - J Biol Chem, 2004 - jbc.org
... Recombinant SCL (TAL1), which is acetylated in vitro by both acetyltransferases
(13 ... The acetylation status of MyoD and YY1 also influences the ability of these ...
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Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction … - Full text - MIT Libraries
SJ KIMBER, P HUSSLEIN - Biochem. J, 2002 - biochemj.org
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Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic ...
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Inferring gene regulatory relationships by combining target-target pattern recognition and regulator … - Full text - MIT Libraries
H Wei, Y Kaznessis - Biotechnology and Bioengineering, 2005 - doi.wiley.com
Page 1. Inferring Gene Regulatory Relationships by Combining Target–Target
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