IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff - Full text - MIT Libraries
M Paulson, C Press, E Smith, N Tanese, DE Levy - Nature Cell Biology, 2002 - nature.com
... Cooperation of Stat2 and p300/CBP in signalling induced by interferon ... Jacq, X. &
Tora, L. Function of TAF(II)-containing complex without TBP in transcription by ...
Cited by 31 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene …
Z Jallow, UG Jacobi, DL Weeks, IB Dawid, GJC … - Proceedings of the National Academy of Sciences - pnas.org
... activation (36). TFTC may be involved in facilitating TBP-independent
STAT2-mediated transcription during viral infection (37). Here ...
Web Search - pubmedcentral.nih.gov - ncmls.kun.nl - dx.doi.org - all 6 versions » - Get it from MIT Libraries

PLENARY SESSIONS ABSTRACTS
IM Kerr, B Lillemeier, B Strobl, H Is’harc, A … - dx.doi.org
... GCN5 but not p300/CBP or PCAF is required for STAT2 function, as is ... and transcriptional
induction can proceed independently of the TATA-binding protein, TBP. ...
Web Search - liebertonline.com - liebertonline.com

Meeting Report Second International Conference on Signal Transduction, Croatia May 2000 - Full text - MIT Libraries
Z Dembic - Scandinavian Journal of Immunology, 2000 - blackwell-synergy.com
... binding of TF II D to the TATA box via the TAF and TBP proteins. ... Active STAT2 recruits
GCN5 factor, which in turn, recruits TAF II 130 creating the TFTC factor ...
Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Activation and repression in the nervous system - Full text - MIT Libraries
RH Goodman, G Mandel - Current Opinion in Neurobiology, 1998 - neuro.neusc.bcm.tmc.edu
... 1 101 461 661 1107 1171 1621 1877 Nuclear hormone receptors Stat1 SF-1 Stat2 TBP
HIF-1 Ets-1 RXR p65 CREB c-Jun c-Myb Tax Sap1 YY1 SREBP ATF-1 ...
Cited by 6 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and … - Full text - MIT Libraries
I Nusinzon, CM Horvath, E Procedures - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... protein (TBP)-associated factor) HAT complex associated with localized transient
histone H3 acetylation (21). For some but not all target promoters, STAT2 can ...
Cited by 16 - Web Search - biochem.northwestern.edu - dx.doi.org - pnas.org - all 8 versions »

Induction of interferon-stimulated gene expression and antiviral responses require protein … - Full text - MIT Libraries
HM Chang, M Paulson, M Holko, CM Rice, BR Williams … - Proceedings of the National Academy of Sciences, 2004 - pnas.org
... This problem is solved, in part, by the ability of Stat2 to mediate gene ... transcription
factor TAF4 but lacking the TATA box-binding protein TBP (9). Such a ...
Cited by 6 - Web Search - pubmedcentral.nih.gov - dx.doi.org - all 6 versions »

Chromatin-remodelling factor BRG 1 selectively activates a subset of interferon-< img border='0' src … - Full text - MIT Libraries
M Huang, F Qian, Y Hu, C Ang, Z Li, Z Wen - Nature Cell Biology, 2002 - nature.com
... Cooperation of Stat2 and p300/CBP in signaling induced by interferon ... E., Tanese,
N. & Levy, DE IFN-stimulated transcription through a TBP-free acetyltransferase ...
Web Search

Impairment of Interferon-Induced IRF-7 Gene Expression due to Inhibition of ISGF3 Formation by …
P Genin, P Morin, A Civas - J. Virol. 77, 2003 - jvi.asm.org
... 1996. Cooperation of Stat2 and p300/CBP by interferon- . ... 2002. IFN-stimulated
transcription through a TBP-free acetyltransferase complex escapes viral shutoff. ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - jvi.asm.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mechanisms of Type I interferon cell signaling and STAT-mediated transcriptional responses - Full text - MIT Libraries
JF Lau, CM Horvath - Mt Sinai J Med, 2002 - mssm.edu
... Interferon, transcription, co-activators, chromatin, STAT1, STAT2, p48, IRF9 ... of
transcription TAD: transcriptional activation domain TAF: TBP-associated factor ...
Cited by 8 - View as HTML - Web Search - ncbi.nlm.nih.gov

Intracellular domain of the IFNaR 2 interferon receptor subunit mediates transcription via Stat 2 - Full text - MIT Libraries
A El Fiky, AE Arch, JJ Krolewski, CFCC Center - Journal of Cellular Physiology, 2005 - doi.wiley.com
... IFN-stimulated tran- scription through a TBP-free acetyltransferase complex escapes ...
Function of Stat2 protein in transcriptional activation by alpha interferon ...
Cited by 2 - Web Search - ucihs.uci.edu - ncbi.nlm.nih.gov

TATA-binding Protein-free TAF-containing Complex(TFTC) and p 300 Are Both Required for Efficient … - Full text - MIT Libraries
S Hardy, M Brand, G Mittler, J Yanagisawa, S Kato, … - J Biol Chem, 2002 - jbc.org
... complex acts as a co-regulator for c-Myc, E2F, STAT2, and several ... has been demonstrated
in vivo that transcription initiation can occur without TBP on certain ...
Cited by 8 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional control of gene expression
W Johnson, JL Jameson - Principles of Molecular Medicine. Humana Press Inc., Towota, …, 1998 - humanapress.com
... CBP/p300 Nuclear Receptors a : (RAR, RXR, ER, TR, PR, GR) CREB, c-Fos, c-Jun, JunB,
YY1, E1a, SV40 Tag, c-Myb, SRC-1, Sap 1a, STAT2, MyoD, E2F-1, TBP, TF II B ...
Cited by 3 - View as HTML - Web Search - modares.ac.ir

A unique ISRE, in the TATA-less human Isg20 promoter, confers IRF-1-mediated responsiveness to both … - Full text - MIT Libraries
CR Guidelines - Nucleic Acids Research, 2000 - nar.oupjournals.org
... The antibodies against Stat1, Stat2, IRF-1 or IRF-2 used for the supershift are ... may
be initiated by the recruitment of the TATA-box binding protein (TBP) by a ...
Cited by 20 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway - Full text - MIT Libraries
JJ O'Shea, M Gadina, RD Schreiber, M Immunology, I … - Cell, 2002 - courses.vcu.edu
... Cells from these mice Stats Stat1 and Stat2 were first identified as
complexes that are ... subunits. Additionally though, Stat2 and ...
Cited by 183 - View as HTML - Web Search - biochem.wisc.edu - ncbi.nlm.nih.gov - all 4 versions »

Chromatin-remodelling factor BRG 1 selectively activates a subset of interferon-α-inducible genes - Full text - MIT Libraries
M Huang, F Qian, Y Hu, C Ang, Z Li, Z Wen - Nature Cell Biology, 2002 - nature.com
... Here we report that BRG1 interacts with signal transducer and activator of
transcription 2 (STAT2) — a transcription factor that reg- ulates gene expression ...
Cited by 22 - Web Search - nature.com - ncbi.nlm.nih.gov

Phosphorylation of the Stat 1 transactivating domain is required for the response to type I … - Full text - MIT Libraries
A Pilz, K Ramsauer, H Heidari, M Leitges, P … - EMBO Reports, 2003 - emboreports.npgjournals.com
... N. & Levy, DE (2002) IFN-stimulated transcription through a TBP-free acetyltransferase ...
Kerr, IM, Stark, GR & Darnell, JE (1996) Function of Stat2 protein in ...
Cited by 1 - Web Search - nature.com - emboreports.npgjournals.com - ncbi.nlm.nih.gov - all 5 versions »

Phosphorylation of the Stat1 transactivating domain is required for the response totype I … - Full text - MIT Libraries
G Hannover - EMBO reports, 2003 - nature.com
... N. & Levy, DE (2002) IFN- stimulated transcription through a TBP-free acetyltransferase ...
Kerr, IM, Stark, GR & Darnell, JE (1996) Function of Stat2 protein in ...
Web Search - nature.com

Global Effect of PEG-IFN- and Ribavirin on Gene Expression in PBMC In Vitro
MW Taylor, WM Grosse, JE Schaley, C Sanda, X Wu, … - Journal of Interferon & Cytokine Research, 2004 - dx.doi.org
Page 1. JOURNAL OF INTERFERON & CYTOKINE RESEARCH 24:107–118 (2004) © Mary Ann
Liebert, Inc. Global Effect of PEG-IFN-a and Ribavirin on Gene ...
Cited by 4 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Characterization of Human Activating Transcription Factor 4, a Transcriptional Activator That … - Full text - MIT Libraries
G Liang, T Hai - J Biol Chem, 1997 - jbc.org
... Myb (17, 18), YY1 (19, 20), Sap-1a (21), MyoD (22, 23), Stat2 (24), SREBP ... between
the sequence-specific transcriptional activators and GTFs such as TBP (22, 33 ...
Cited by 44 - Web Search - jbc.org - ncbi.nlm.nih.gov

Role of metazoan mediator proteins in interferon-responsive transcription - Full text - MIT Libraries
JF Lau, I Nusinzon, D Burakov, LP Freedman, CM … - Mol. Cell. Biol, 2003 - mcb.asm.org
... IFN-stimulated transcription through a TBP-free acetyltransferase complex escapes
viral shutoff. ... Function of Stat2 protein in transcriptional activation by IFN ...
Cited by 7 - Web Search - pubmedcentral.nih.gov - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 … - Full text - MIT Libraries
LK Felzien, S Farrell, JC Betts, R Mosavin, GJ … - Mol. Cell. Biol, 1999 - mcb.asm.org
... p300, and p300-associated proteins, are components of TATA-binding protein (TBP)
complexes ... Cooperation of Stat2 and p300/CBP in signalling induced by interferon ...
Cited by 31 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Identification of p 100 as a coactivator for STAT 6 that bridges STAT 6 with RNA polymerase II - Full text - MIT Libraries
J Yang, S Aittomaeki, M Pesu, K Carter, J Saarinen … - The EMBO Journal, 2002 - embojournal.npgjournals.com
... Green,MR (2000) TBP-associated factors (TAFIIs): multiple, selective transcriptional
mediators in ... Stat6 and leads to the formation of Stat2:Stat6 complexes in ...
Cited by 10 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

Signalling: Stats: transcriptional control and biological impact - Full text - MIT Libraries
DE Levy, JE Darnell - Nature Reviews Molecular Cell Biology, 2002 - nature.com
1. Fu, XY, Schindler, C., Improta, T., Aebersold, R. & Darnell, J. E.Jr. The
proteins of ISGF-3: the interferon -induced transcriptional ...
Cited by 166 - Web Search - jhcourse.jhu.edu - medicine.facmed.utoronto.ca - qb.fcen.uba.ar - all 14 versions »

Assessment of the gene expression profile of differentiated and dedifferentiated human fetal … - Full text - MIT Libraries
DG Stokes, G Liu, IB Coimbra, S Piera-Velazquez, … - Arthritis & Rheumatism, 2002 - doi.wiley.com
... Transcription factor IIH (44-kd subunit) Hs.191356 3 1.1 7508 STAT2 Hs.72988 3
1.2 5398 (TBP)-associated factor IIA (250 kd) Hs.1179 3 1.2 5292 ...
Cited by 22 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Modulation of Smooth Muscle Gene Expression by Association of Histone Acetyltransferases and … - Full text - MIT Libraries
D Cao, Z Wang, CL Zhang, J Oh, W Xing, S Li, JA … - Mol Cell Biol, 2005 - mcb.asm.org
... These include the amino-terminal zinc finger domain CH1, which interacts with TBP,
RXR, STAT2, and others; the CREB-binding domain in the middle of the protein ...
Cited by 3 - Web Search - mcb.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

p 300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat 6 - Full text - MIT Libraries
S Gingras, J Simard, B Groner, E Pfitzner - Nucleic Acids Research, 1999 - nar.oupjournals.org
... Recently it has been shown that Stat1, Stat2 and Stat5 also interact ... by bridging
transcription factors to basal transcription machinery, eg TFIIB, TBP and RNA ...
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Down-modulation of responses to type I IFN upon T cell activation - Full text - MIT Libraries
E Dondi, L Rogge, G Lutfalla, G Uze, S Pellegrini - The Journal of Immunology, 2003 - jimmunol.org
... Cooperation of Stat2 and p300/CBP in signalling induced by interferon ... IFN-stimulated
transcription through a TBP-free acetyltransferase complex escapes viral ...
Cited by 9 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

The chromatin-remodeling BAF complex mediates cellular antiviral activities by promoter priming - Full text - MIT Libraries
K Cui, P Tailor, H Liu, X Chen, K Ozato, K Zhao - Mol. Cell. Biol, 2004 - pubmedcentral.nih.gov
... Cooperation of Stat2 and p300/CBP in signalling induced by interferon ... IFN-stimulated
transcription through a TBP-free acetyltransferase complex escapes viral ...
Cited by 4 - Web Search - ucsf.edu - dx.doi.org - mcb.asm.org - all 6 versions »

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
... DEK 6p23 NM_021145 cyclin D binding myb-like DMTF1 7q21 transcription factor 1
NM_001938 down-regulator of transcription DR1 1p22.1 1, TBP-binding (negative ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

Regulation of CBP-mediated transcription by neuronal calcium signaling - Full text - MIT Libraries
SC Hu, J Chrivia, A Ghosh - Neuron, 1999 - www-biology.ucsd.edu
... Recruitment of scription activator and interacts with the TBP-associ- CBP ...
concentrations minal domain includes the TBP interaction sites (Swope ...
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Involvement of CREB binding protein in expression of major histocompatibility complex class II genes … - Full text - MIT Libraries
A Kretsovali, T Agalioti, C Spilianakis, E … - Mol. Cell. Biol, 1998 - mcb.asm.org
... Cooperation of Stat2 and p300/CBP in signaling induced by interferon- . ... The class
II trans-activator CIITA interacts with the TBP-associated factor TAFII32. ...
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[CITATION] Histone Deacetylases as Transcriptional Activators? Role Reversal in Inducible Gene Regulation
I Nusinzon, CM Horvath - proteins
... Smith, N. Tanese, DE Levy, IFN-stimulated transcription through a TBP-free
acetyltransferase ... Z. Arany, A. D'Andrea, DM Livingston, Cooperation of Stat2 and ...
Web Search - stke.org - Get it from MIT Libraries

UTF 1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra- … - Full text - MIT Libraries
A Okuda, A Fukushima, M Nishimoto, A Orimo, T … - The EMBO Journal, 1998 - embojournal.npgjournals.com
... F9 (left and middle panels) or NIH 3T3 cell (right panel) nuclear extracts (200
µl) were immunoprecipitated with either polyclonal anti-TBP or anti-UTF1 ...
Cited by 27 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

The viral control of cellular acetylation signaling - Full text - MIT Libraries
C Caron, E Col, S Khochbin - BioEssays, 2003 - doi.wiley.com
... (18,28,29) Furthermore, Tat seems to en- hance the binding of p300/CBP to the basal
transcription factors TBP and TFIIB, (23) as well as to induce the ...
Cited by 15 - Web Search - ncbi.nlm.nih.gov

PU. 1/Interferon Regulatory Factor Interactions
S Marecki, MJ Fenton - Cell Biochemistry and Biophysics, 2000 - journals.humanapress.com
... I/Y, NF-κB, AP-1, Retinoblastoma (Rb), TATA binding pro- tein (TBP), and CREB ...
(ISGF3-γ, a trimeric complex consisting of p48/IRF9, STAT1, and STAT2) and four ...
Cited by 24 - Web Search - neurosci.humanapress.com - now.humanapress.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

The Roles of Inflammation, STAT Transcription Factors, and Nerve Growth Factor in Viral Reactivation …
MA Liebert, I Pp - DNA AND CELL BIOLOGY, 2002 - dx.doi.org
... The presence of STAT1, STAT2, STAT3, STAT5b, and STAT6 in TG neurons from ... antibodies,
and TG nuclear extracts with anti-TATA binding protein (TBP) antibodies. ...
Web Search - liebertonline.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

The role of IRF-4 in transcriptional regulation
S Marecki, MJ Fenton - J. Interferon Cytokine Res, 2002 - dx.doi.org
... a trimeric complex consisting of p48/IRF- 9, Stat1, and Stat2), and four viral ... protein
1 (AP-1), retinoblastoma (Rb), TATA binding protein (TBP), CREB binding ...
Cited by 13 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Regulatory targets in the RNA polymerase II holoenzyme
JD Parvin, RA Young - Curr. Opin. Genet. Dev, 1998 - parvinlab.bwh.harvard.edu
... Abbreviations CTD carboxy-terminal domain HAT histone acetyltransferase Pol II RNA
polymerase II TAFs TBP-associated factors USA upstream stimulatory activity ...
Cited by 34 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

RNA helicase A mediates association of CBP with RNA polymerase II - Full text - MIT Libraries
T Nakajima, C Uchida, SF Anderson, CG Lee, J … - Cell, 1997 - parvinlab.bwh.harvard.edu
... transcriptional apparatus via a constitutive in- teraction with the TBP-associated
factor ... Cooperation of STAT2 and P300/CBP insignaling induced by interferon-a ...
Cited by 233 - View as HTML - Web Search - ncbi.nlm.nih.gov

Interferon-independent and-induced regulation of Epstein-Barr virus EBNA-1 gene transcription in … - Full text - MIT Libraries
C Nonkwelo, IK Ruf, J Sample - J. Virol, 1997 - jvi.asm.org
... IRF-1 and TBP antibodies were obtained from Santa Cruz Biotechnology; IRF-2 and ... trans-
ducer and activator of transcription factor 1 (STAT1), STAT2, and ISGF3 ...
Cited by 32 - Web Search - jvi.asm.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon- … - Full text - MIT Libraries
M Osaki, L Tan, BK Choy, Y Yoshida, KS Cheah, PE … - Biochem. J, 2003 - biochemj.org
... responses to IFN-γ were retained in the U6A (Stat2-deficient) cell line ... is able to
promote more effective interaction with TATA binding protein (TBP)/TFIID. ...
Cited by 15 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

A BAF-centred view of the immune system - Full text - MIT Libraries
T Chi - Nature Reviews Immunology, 2004 - nature.com
... | Article | PubMed | ISI | ChemPort |. 36. Lomvardas, S. & Thanos, D. Nucleosome
sliding via TBP DNA binding in vivo. Cell 106, 685–696 (2001). ...
Web Search - nature.com - ncbi.nlm.nih.gov

[CITATION] The Ins and Outs of STAT1 Nuclear Transport
KM McBride, NC Reich - Sci. STKE, 2003
... Z. Arany, A. D'Andrea, DM Livingston, Cooperation of Stat2 and p300 ... Smith, N. Tanese,
DE Levy, IFN-stimulated transcription through a TBP-free acetyltransferase ...
Cited by 4 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Signal transducer and activator of transcription(STAT) signalling and T-cell lymphomas - Full text - MIT Libraries
TJ Mitchell, S John - Immunology, 2005 - blackwell-synergy.com
... cytokine-induced STAT activation. The mammalian STAT family comprises Stat1,
Stat2, Stat3, Stat4, Stat5a, Stat5b and Stat6. 20 The two ...
Web Search - ingentaconnect.com - immuneweb.xxmc.edu.cn - ncbi.nlm.nih.gov

The Mediator of RNA polymerase II - Full text - MIT Libraries
EBGMM Meisterernst - Chromosoma, 2005 - springerlink.com
... intact TATA box binding factor led to discovery of a group of TBP-associated factors
(TAFs), which together with TBP form the TFIID ... (1999) STAT2 MED14, MED17 ...
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Inverse Interference: How Viruses Fight the Interferon System
F Weber, G Kochs, O Haller - Viral Immunology, 2004 - dx.doi.org
... induction (21) Herpes simplex virus Unknown JAK1, STAT2 (33,238) SOCS-3 induction
Murine cytomegalovirus M27 protein STAT2 (102) Murine ...
Cited by 2 - Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Inhibition of human papillomavirus-16 long control region activity by interferon-gamma overcome by p … - Full text - MIT Libraries
V Fontaine, E van der Meijden, J ter Schegget - Molecular Carcinogenesis, 2001 - doi.wiley.com
... TATAA: TATAA box. TBP: TATA binding proteins. ... 34 FONTAINE ET AL. Page 9. tion of
STAT2, which can compete with NF-kB to bind p300/CBP cofactors. ...
Cited by 3 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB- … - Full text - MIT Libraries
X Shen, PP Hu, NT Liberati, MB Datto, JP Frederick … - Mol. Biol. Cell, 1998 - intl.molbiolcell.org
... Cooperation of Stat2 and p300/CBP in signaling by interferon. ... antibodies raised against
p300: both p300 and CBP are present in intracellular TBP complexes. ...
Cited by 106 - Web Search - molbiolcell.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov

Transgenic Expression in Mouse Lung Reveals Distinct Biological Roles for the Adenovirus Type 5 E1A … - Full text - MIT Libraries
Y Yang, C McKerlie, SH Borenstein, Z Lu, M Schito, … - J Virol, 2002 - jvi.asm.org
... 1) such as TBP, APs, and ATFs (6, 11, 12, 20, 26, 29). ... 1996. Cooperation of
Stat2 and p300/CBP in signalling induced by interferon-alpha. ...
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