Differential gene expressions during immortalization of normal human fibroblasts and endothelial … - Full text - MIT Libraries
T Kumazaki, K Hiyama, T Takahashi, H Omatsu, K … - Int J Oncol, 2004 - 147.52.72.117
... on-Demand Gene Expression products (Applied Biosystems) for PCNA, RB1, TP53, APAF1,
CDKN1A, CCND1, and internal controls ACTB, GAPD, and TBP, Pre-Developed ...
View as HTML - Web Search - ncbi.nlm.nih.gov

Distinct and Complementary Information Provided by Use of Tissue and DNA Microarrays in the Study of … - Full text - MIT Libraries
C Ginestier, E Charafe-Jauffret, F Bertucci, F … - development - ajp.amjpathol.org
... GTTTCTGCAGGTAATGGTGGC-3 (exon 7) Probe 5 -CCCATGGGCGCTATGTGCCC-3 TBP Forward primer
5 ... addition, other molecules, such as CDH1, Ki67, TP53, progesterone receptor ...
Cited by 24 - Web Search - ingentaconnect.com - utoronto.ca - ncbi.nlm.nih.gov - all 6 versions »

Roles of p 300, pocket proteins, and hTBP in E 1 A-mediated transcriptional regulation and … - Full text - MIT Libraries
N Sang, ML Avantaggiati, A Giordano - Journal of Cellular Biochemistry, 1997 - doi.wiley.com
... complex is required for p53 transactivation and that disruption of p300/ TBP/TFIIB
function is ... lines derived from human osteosarcoma, U-2OS (RB 1/1 , TP53 1/1 ...
Cited by 19 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Does MSI-low exist? - Full text - MIT Libraries
I Tomlinson, S Halford, L Aaltonen, N Hawkins, R … - The Journal of Pathology, 2002 - doi.wiley.com
... Fixed, archival APC, D9S171 , TP53, Mfd25, MId28 BAT25; BAT26; ... D1 3S175 ; D1 8S58;
D1 8S69 AR: TBP; SR: HPRT1 ; HPR TII; MYC L1: RB: REN > 20% uns table N/A ...
Cited by 18 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Molecular Profiling of Inflammatory Breast Cancer - Full text - MIT Libraries
I Bieche, F Lerebours, S Tozlu, M Espie, M Marty, … - Clinical Cancer Research, 2004 - clincancerres.aacrjournals.org
... mechanisms underlying the genesis and progression of IBC (3) . TP53 and ERBB2 ... genes
involved in two cellular metabolic pathways, namely TBP (GenBank accession ...
Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

Quantitative RT-PCR in cirrhotic nodules reveals gene expression changes associated with liver … - Full text - MIT Libraries
M Colombat, V Paradis, I Bieche, D Dargere, I … - The Journal of Pathology, 2003 - doi.wiley.com
... of HCC, such as loss of heterozygosity at 8p22, 17p13.1 (TP53), 13q (RB1 ... We therefore
also quantified transcripts of the gene TBP (Genbank accession NM 003194 ...
Cited by 1 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis … - Full text - MIT Libraries
P Levy, D Vidaud, K Leroy, I Laurendeau, J … - Molecular Cancer, 2004 - dx.doi.org
... p53 in the progression of MPNSTs, mice that harbor both NF1 and TP53 mutations develop ...
The mean TBP gene Ct (threshold cycle) values for the four tumor samples ...
Web Search - pubmedcentral.nih.gov - bmc.ub.uni-potsdam.de - molecular-cancer.com - all 10 versions »

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells - Full text - MIT Libraries
Z Li, S Van Calcar, C Qu, WK Cavenee, MQ Zhang, B … - Proceedings of the National Academy of Sciences, 2003 - pnas.org
... Myc was shown to interact directly with TATA-box-binding protein (TBP) (37, 38 ... P23,
PA2G4, PCNA, PCTK1, PPP2CA, PSMD8, RBBP8, RBL1, SGT1, TOPBP1, TP53, and TSC2 ...
Cited by 46 - Web Search - panomics.com - zlab.bu.edu - rulai.cshl.org - all 10 versions »

Induction of Radioresistance by a Nitric Oxide-Mediated Bystander Effect - Full text - MIT Libraries
H Matsumoto, S Hayashi, M Hatashita, K Ohnishi, H … - Radiation Research, 2001 - bioone.org
... suggested that the activity of TATA-box binding protein (TBP), which is essential
for NOS2 expression, may be suppressed by binding with wild-type TP53 (8, 33 ...
Cited by 28 - Web Search - apt.allenpress.com - ingentaconnect.com - all 7 versions »

CHK 1 frameshift mutations in genetically unstable colorectal and endometrial cancers
F Bertoni, AM Codegoni, D Furlan, MG Tibiletti, C … - Genes Chromosomes and Cancer, 1999 - doi.wiley.com
... D2S123, D2S119, D3S1611, APC, D7S481, D7S517, D13S175, D17S787, TP53, and DCC)and
14 (D6S87, D6S255, D6S193, D6297, D6S149, D6281, D6446, TBP, D2S123, D3S111 ...
Cited by 31 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Two cellular proteins that bind to wild-type but not mutant p53 - Full text - MIT Libraries
K Iwabuchi, PL Bartel, B Li, R Marraccino, S … - Proc. Natl. Acad. Sci. USA, 1994 - pnas.org
... 1). Introduction of the wild-type p53 gene (human gene symbol, TP53) into cells ... 1).
The cellular proteins MDM2 (2, 3), TATA-binding protein (TBP) (4, 5), and ...
Cited by 107 - Web Search - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - adsabs.harvard.edu - all 6 versions »

Identification of a proliferation gene cluster associated with HPV E6/E7 expression level and viral …
C Rosty, M Sheffer, D Tsafrir, N Stransky, I … - Oncogene. In press, 2005 - weizmann.ac.il
... uterine cervix. Viral E6 and E7oncogenes are key mediators in cell
transformation by disrupting TP53 and RB pathways. To investigate ...
Cited by 2 - View as HTML - Web Search

GEArray Q series Human p53 Signaling Pathway Gene Array: AR-SAHS-027
FG Grouping - eurogentec.com
... Functional Gene Grouping p53 family: TP53, TP63, TP73 ... LRDD, MAP4, NDRG (RTP), PIG8
(E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP, THRA, TNFAIP1 ...
View as HTML - Web Search - eurogentec.be

GEArray Q series Human p53 Signaling Pathway Gene Array Cat. No.* Kit Size HS-027-2/HS-027N-2 2 …
FG Grouping - tebu-bio.com
... Functional Gene Grouping p53 family: TP53, TP63, TP73 ... LRDD, MAP4, NDRG (RTP), PIG8
(E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP, THRA, TNFAIP1 ...
View as HTML - Web Search

GEArray Q series Human p53 Signaling Pathway Gene Array
FG Grouping - superarray.com
... p53 family: TP53, TP63, TP73 ... HIF1A, HSPA4 (Hsp70), LRDD, MAP4, NDRG (RTP), PIG8
(E124), PMP22, RELA, REPRIMO, SFN (14-3-3), SP1, STAT5A, TBP, THRA, TNFAIP1 ...
View as HTML - Web Search - superarray.com - cosmobio.co.jp - cosmobio.co.jp - all 5 versions »

A separation-free assay for the detection of mutations: Combination of homogeneous time-resolved … - Full text - MIT Libraries
E Lopez-Crapez, H Bazin, J Chevalier, E Trinquet, … - Human Mutation, 2005 - doi.wiley.com
... KEY WORDS: HTRF; FRET; Europium cryptate; mutation detection; minisequencing; TP53 ...
Europium cryptate, symbolized by tris-bipyridine [TBP(Eu 3+ )], has been ...
Web Search - ncbi.nlm.nih.gov

analysis in Drosophila melanogaster
G product Selected - www-biology.ucsd.edu
... inaC § , Pkc53E Ca 2+ -dependent PKC SCA17 (also known asTBP) Tbp § TATA binding
protein ... Hepatocellular carcinoma TP53 hth § (e <10 –10 ) Cell cycle ...
Web Search - nature.com

Protein kinase CK2-dependent regulation of p53 function: Evidence that the phosphorylation status of …
L McKendrick, D Milne, D Meek - Mol Cell Biochem, 1999 - springerlink.com
... The cells were grown at 37°C in a humidified in- cubator with 5% CO 2 . The tp53
protein is a highly stable C-terminal fragment of p53 comprising amino acids ...
Cited by 7 - Web Search - kluweronline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

[BOOK] Familial cancer and prevention: molecular epidemiology: a new strategy toward cancer control
J Utsunomiya, JJ Mulvihill, W Weber - 1999 - print.google.com
Page 1. UICC International Union Against Cancer FAMILIAL CANCER AND PREVENTION
iiiIIIII I IIIIlIII Th isO fl • 8YYW DKF EN0C Page 2. ...
Cited by 1 - Web Search - Get it from MIT Libraries - Library Search

p53 and brain tumors: from gene mutations to gene therapy - Full text - MIT Libraries
G Fulci, N Ishii, EG Van Meir - Brain Pathol, 1998 - brainpathology.com
... proteins (Table 2); notably, its interaction with CBF/CBP and TBP inhibits
transactivation of ... for the high frequency of mutations found at the TP53 locus in ...
Cited by 37 - Web Search - brainpath.medsch.ucla.edu - brainpath.medsch.ucla.edu - ncbi.nlm.nih.gov

Unique Features of the Mode of Action of ET-743 - Full text - MIT Libraries
M D'Incalci, E Erba, G Damia, E Galliera, L … - The Oncologist, 2002 - theoncologist.alphamedpress.org
... DNA binding was found for Sp1, Maf, MYB, or MYC, while for TBP, E2F, and ... cells from
the A2780/CX3 subline transfected with a dominant-negative mutant TP53 [26 ...
Cited by 12 - Web Search - dx.doi.org - theoncologist.alphamedpress.org - ncbi.nlm.nih.gov

FMGA: finding motifs by genetic algorithm
FFM Liu, JJP Tsai, RM Chen, SN Chen, SH Shih - Bioinformatics and Bioengineering, 2004. BIBE 2004. …, 2004 - ieeexplore.ieee.org
... Besides TBP and Sp1 factors, there are also other factors to aid the DNA ... E-cadherin
(CDH1), E2F1, FABP3, FHIT, M6PR, IGF2R, NF2, NME1, PTEN, TGFB1, TP53 We set ...
Cited by 1 - Web Search - doi.ieeecomputersociety.org - ieeexplore.ieee.org

The p 53 story: layers of complexity - Full text - MIT Libraries
AW Braithwaite, JA Royds, P Jackson - Carcinogenesis, 2005 - carcin.oxfordjournals.org
... for patients with Dukes' C stage rectal tumours if they harboured a wt TP53. ... Histone
acetyl transferase (HAT; bound to p53) and TBP (bound to the TATA-box) are ...
Web Search - carcin.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov

HUMAN pHYDE IS NOT A CLASSICAL TUMOR SUPPRESSOR GENE IN PROSTATE CANCER - Full text - MIT Libraries
F Tampere - Int. J. Cancer, 2003 - doi.wiley.com
... known clas- sical tumor suppressor genes, only mutations of TP53 and PTEN ... the expression
levels, the expression of TATA- box binding protein (TBP) was measured ...
Web Search

Function and dysfunction of the human oncoprotein MDM2
SP Deb - Frontiers in Bioscience, 2002 - bioscience.org
... 276) rich in acidic amino acids is needed for interaction with TBP (94) (Figure
1 ... Reuter VE, &Cordon-Cardo C.: Altered patterns of MDM2 and TP53 expression in ...
Cited by 10 - Cached - Web Search - xylian.igh.cnrs.fr - bioscience.org - ncbi.nlm.nih.gov - all 7 versions » - Get it from MIT Libraries

An update on the molecular genetics of hepatocellular carcinoma - Full text - MIT Libraries
A Suriawinata, R Xu - Semin Liver Dis, 2004 - thieme-connect.com
... TP53 and liver carcinogenesis. ... and with elements of the basal transcription machinery
transcription factor IIB [TFIIB], TATA Box-binding protein [TBP], and RNA ...
Cited by 6 - Web Search - thieme-connect.com - ncbi.nlm.nih.gov

An integrated linkage-radiation hybrid map of the canine genome - Full text - MIT Libraries
CS Mellersh, C Hitte, M Richman, F Vignaux, C … - Mammalian Genome, 2000 - springerlink.com
... retained in any of the radiation hybrids is the tumor suppressor gene TP53, located
on ... on CFA12 indicate that the most likely order of markers is TBP–C12.406 ...
Cited by 84 - Web Search - ncbi.nlm.nih.gov

Analysis of the transcription regulator, CNOT 7, as a candidate chromosome 8 tumor suppressor gene … - Full text - MIT Libraries
J Flanagan, S Healey, J Young, V Whitehall, G … - International Journal of Cancer, 2003 - doi.wiley.com
... to the LOH on chromosomes 5 and 17 where the APC and TP53 genes are ... be involved in
global gene regulation by modulation of TATAA-binding protein (TBP) activity ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The role of transforming growth factor-β in glioma progression
MT Jennings, JA Pietenpol - J. Neuro-Oncol, 1998 - springerlink.com
... The frequency of mutations within glioma-associated TSG, such as TP53 and RB, suggests
that defects in TGFβ’s inhibitory signaling pathway may have ...
Cited by 19 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Hepatocellular carcinoma: molecular interactions between hepatitis C virus and p53 in …
M Anzola, JJ Burgos - Expert Rev Mol Med, 2003 - journals.cambridge.org
... of NS5A give rise to smaller molecular weight forms that are able to translocate
to the nucleus and interact with TATA-box-binding protein (TBP), p53 and ...
Cited by 1 - Web Search - dx.doi.org - www-ermm.cbcu.cam.ac.uk - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

p 53: Biology and Role for Cellular Radiosensitivity - Full text - MIT Libraries
J Dahm-Daphi - Strahlentherapie und Onkologie, 2000 - springerlink.com
... These domaines bind to the basal transcription machinery (ie TFIIH, TBP, p300/CBP)
having both enhancing and repressing activity. ... TFII H TBP topo l Page 4. ...
Cited by 21 - Web Search - ncbi.nlm.nih.gov

Mdm-2:‘‘Big Brother’’of p53 - Full text - MIT Libraries
D TUMORIGENESIS - Journal of Cellular Biochemistry, 1997 - doi.wiley.com
... Partial overlap of the binding sites for Mdm-2, TBP, and the TAFs ... gene amplification
and transcript levels in human sarcomas: Relationship to TP53 gene status. ...
Web Search - doi.wiley.com

Development of a fluorescent multiplex assay for detection of MSI-High tumors
JW Bacher, LA Flanagan, RL Smalley, NA Nassif, LJ … - Disease Markers, 2004 - iospress.metapress.com
... TP53-penta Penta – 14% (4/29) 97% (28/29) A Mean 27% 99% ... using fluorescently labeled
primers for mono- (BAT-40), di- (D5S346), tri- (TBP), tetra- (D5S818 ...
Cited by 2 - Web Search - promega.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in … - Full text - MIT Libraries
M Anzola - Journal of Viral Hepatitis, 2004 - blackwell-synergy.com
... NS5A forms a heteromeric complex with TATA box binding protein (TBP) and
tumour-suppressor protein p53 [100]. NS5A inhibits the ...
Cited by 1 - Web Search - blackwell-synergy.com - ingentaconnect.com - ncbi.nlm.nih.gov

Adams PD; Kaelin WG Jr Transcriptional control by E2F. Semin Cancer Biol 6: 99-108 (1995) - Full text - MIT Libraries
V Adams, W Kempf, S Hassam, J Briner, M Schmid, R … - Semin Cancer Biol, 1995 - stdgen.lanl.gov
... al-Ghamdi AA; Sanders CM; Keefe M; Coggon D; Maitland NJ Human papillomavirus
DNA and TP53 mutations in lung cancers from butchers. ...
Cited by 63 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell … - Full text - MIT Libraries
C Cadwell, GP Zambetti - Gene, 2001 - bio.kaist.ac.kr
... 3). The N-terminus of p53 contains an acidic domain (amino acids 1–42) that interacts
with components of the transcriptional machinery, such as TBP and TAFs, ...
Cited by 37 - View as HTML - Web Search - ncbi.nlm.nih.gov

Diploid, microsatellite stable rectal carcinomas show different molecular phenotypes
E Kapiteijn, WJF de Leeuw, RW van der Gaag, PJJ … - openaccess.leidenuniv.nl
... D8S1130, D15S1232, D16S752, TP53). ... markers. The highest frequencies of LOH
were detected at the TP53 (58%) and D5S346 (42%) loci. ...
View as HTML - Web Search - etcl04.leidenuniv.nl - etcl.nl

Der Tumorsuppressor p53 und Adenoviren als Transkriptionsmodulatoren
D der Naturwissenschaften, K Loehr, M an der Lahn - archiv.ub.uni-marburg.de
... Faktoren, wie zB p300, das TATA-Box binding protein (TBP) (Chen et al., 1995) oder
TFIID (Horikoshi et al., 1995). ... Abbildung 1.5: Genstruktur von TP53/TP73. ...
View as HTML - Web Search - archiv.ub.uni-marburg.de

Aberrant regulation and function of wild-type p53 in radioresistant melanoma cells - Full text - MIT Libraries
K Satyamoorthy, NH Chehab, MJ Waterman, MC Lien, … - Cell Growth Differ, 2000 - cgd.aacrjournals.org
... T., Holm R., Skrede M., Borresen AL, Nesland JM, Fodstad O. TP53 allele loss ... Pan
S., Sehnke PC, Ferl RJ, Gurley WB Specific interactions with TBP and TFIIB in ...
Cited by 20 - Web Search - wistar.upenn.edu - cgd.aacrjournals.org - ncbi.nlm.nih.gov

Differentially Expressed Genes in Prostate Cancer
K PORKKA - acta.uta.fi
... epithelial antigen of the prostate STEAP2 six-transmembrane epithelial antigen of
the prostate 2 TIARP TNFα-induced adipose-related protein TP53 tumor protein ...
Web Search

Li-Fraumeni syndrome and the role of the p53 tumor suppressor gene in cancer susceptibility
M Akashi, HP Koeffler - Clin Obstet Gynecol, 1998 - clinicalobgyn.com
... p53 inhibits the transcription of TATA-controlled genes, perhaps by binding to
TATA-binding proteins (TBP).61 Wild-type p53 also may suppress the transcription ...
Cited by 9 - Web Search - clinicalobgyn.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Journal of Biological Chemistry Home Help [Feedback][For Subscribers][Archive][Search][Contents] - Full text - MIT Libraries
H Carcinoma, H Virus - J. Virol, 2004 - pnas.org
... Home page, Carcinogenesis Home page JL Torino, MS Burger, CA Reznikoff, and S.
Swaminathan Role of TP53 in repair of N-(deoxyguanosin-8-yl)-4-aminobiphenyl ...
Web Search

The Review
BR STRATEGIES, D READING, A READING - jncicancerspectrum.oupjournals.org
... The history of investigations of the p53 (also known as TP53) tumor suppressor gene
is ... perhaps by p53 binding to the TATA binding protein (TBP) and inhibiting ...
Web Search - eduplace.com

Different gene expression of MDM 2, GAGE-1,–2 and FHIT in hepatocellular carcinoma and focal … - Full text - MIT Libraries
T Schlott, K Ahrens, I Ruschenburg, S Reimer, H … - British Journal of Cancer, 1999 - nature.com
... acidic domain of MDM2 interacts with the TATA-binding protein TBP (Leveillard and ...
F, Yokomori K and Hayashi Y (1996) Infrequent mutations of the TP53 gene and ...
Cited by 14 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

BLOOD - Full text - MIT Libraries
M Prokocimer, V Rotter - Blood, 1994 - bloodjournal.org
... p53 was also shown to inhibit the expression of transcription of TATA- controlled
genes, perhaps by binding to TATA binding pro- teins (TBP) or other ...
Cited by 11 - Web Search

Cell-cycle checkpoint kinases: checking in on the cell cycle
NC Walworth - Curr. Opin. Cell Biol, 2000 - microarray1.princeton.edu
... 182. 6. Wahl GM, Linke SP, Paulson TG, Huang LC: Maintaining genetic stability
through TP53 mediated checkpoint control. In Cancer ...
Cited by 54 - View as HTML - Web Search - surrey.ac.uk - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Altered DNA repair capacity in young patients suffering from multiple cancers - Full text - MIT Libraries
U MUeLLER-VOGT, JEE MAURER, GG GRABENBAUER, LVR … - INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2003 - virology.med.uoc.gr
... testicular carcinoma (like i12p mutations) (22), skin tumors (for example TP53
mutations) (23,24 ... SA, Guan Y, et al: Reduced expression of hMLH1 and TBP/hMSH6: a ...
Cited by 2 - View as HTML - Web Search - 147.52.72.117 - ncbi.nlm.nih.gov

Bedeutung des ABC-Transporters MRP2/cMOAT/ABCC2 bei der Cisplatinresistenz humaner Tumorzellen
PDJ Mlynek, PDM Linscheid - dochost.rz.hu-berlin.de
... Vincristin und Etoposid der untersuchten Zellinien. 60 Tab. 3.2: TP53-Status
in den untersuchten Zellinien. 61 Tab. 3.3: Real-time ...
View as HTML - Web Search - edoc.hu-berlin.de - edoc.hu-berlin.de - edoc.hu-berlin.de - all 5 versions »

Untersuchung alternativer Mechanismen der Genregulation durch Oestrogenrezeptor-Isoformen
T Floetotto - deposit.ddb.de
... Translation Kofaktoren B Pol II Transkription TATA TBP ER ER EE ERE A F TAFs E E ...
Translation Kofaktoren B Pol II Transkription TATA TBP ER ER EE ERE A F TAFs E ...
Web Search

Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG 2 … - Full text - MIT Libraries
M Hammarsund, W Wilson, M Corcoran, M Merup, S … - Human Genetics, 2001 - springerlink.com
... factors, such as CREB, AP1, TCF, USF, IK-2, ETS-1, TBP and TFIID (Fig.2 and ... on
chromosome 5q in ovarian cancer is frequently accompanied by TP53 mutation and ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov