Wnt3a minus/minus-like phenotype and limb deficiency in Lef1 minus/minus Tcf1 minus/minus mice - Full text - MIT Libraries
J Galceran, I Farinas, MJ Depew, H Clevers, R … - GENES & DEVELOPMENT - genesdev.org
... In Lef1 / Tcf1 / embryos, En1 is not expressed in the forelimb bud, although abundant
expression can be detected at the mid-/hindbrain boundary (Fig. ...
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Polarity and laminar formation of the optic tectum in relation to retinal projection - Full text - MIT Libraries
H Nakamura, S Sugiyama - Journal of Neurobiology, 2004 - doi.wiley.com
... gradient of ephrinA2 and -A5 in the tectum is regu- lated by En1 and En2 ... Because
Tcf1 and Tcf3 are expressed in the di-mes- encephalic region, it was proposed ...
Web Search - ncbi.nlm.nih.gov

BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral … - Full text - MIT Libraries
S Pizette, C Abate-Shen, L Niswander - Development, 2001 - dev.biologists.org
... effect on Wnt7a or indirect through the regulation of En1 expression ... is implicated
in endogenous AER formation through the activation of TCF1/LEF1 transcription ...
Cited by 34 - Web Search - dev.biologists.org - uvm.edu - ncbi.nlm.nih.gov

mBtd is required to maintain signaling during murine limb development - Full text - MIT Libraries
D Treichel, F Schoeck, H Jaeckle, P Gruss, A … - Genes & Development, 2003 - genesdev.org
... Furthermore, simultaneous inactivation of Lef1 and Tcf1, the mediators of the Wnt
signaling pathway, abolishes En1 expression and prevents limb outgrowth ...
Cited by 4 - Web Search - genesdev.org - pubmedcentral.nih.gov - dx.doi.org - all 7 versions »

Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation - Full text - MIT Libraries
RA Kimmel, DH Turnbull, V Blanquet, W Wurst, CA … - Genes Dev, 2000 - genesdev.org
... One border is transient and at the limit of expression of the ventral gene En1,
which corresponds to the D/V midline of the AER, and the second border ...
Cited by 38 - Web Search - genesdev.org - saturn.med.nyu.edu - pubmedcentral.nih.gov - all 7 versions »

Wnts and wing: Wnt signaling in vertebrate limb development and musculoskeletal morphogenesis
Y Yang - Birth Defects Research Part C Embryo Today Reviews, 2003 - doi.wiley.com
... As both Lef1 and Tcf1 are expressed in the limb meso- derm, it is possible that ...
canonical Wnt sig- naling is also required upstream of Engrailed 1(En1) in the ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Tbx 5 is essential for forelimb bud initiation following patterning of the limb field in the mouse … - Full text - MIT Libraries
P Agarwal, JN Wylie, J Galceran, O Arkhitko, C Li, … - Development, 2003 - dev.biologists.org
... Lef1/Tcf1-dependent Wnt signaling is not essential for initiation of Tbx5 or Fgf10
transcription, but is required in concert with Tbx5 for maintenance of ...
Cited by 22 - Web Search - mstp.northwestern.edu - mstp.nwu.edu - dx.doi.org - all 8 versions »

A role for the mesenchymal T-box gene Brachyury in AER formation during limb development - Full text - MIT Libraries
C Liu, E Nakamura, V Knezevic, S Hunter, K … - Development, 2003 - dev.biologists.org
... is not primarily affected by loss of T function; reduced Bmp4 and irregular En1
and Wnt7a ... Wnt3a -/- like phenotype and limb deficiency in Lef1 -/- Tcf1 -/- mice ...
Cited by 6 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic … - Full text - MIT Libraries
M Ishibashi, AP McMahon - Development, 2002 - dev.biologists.org
... (EJ) Expression patterns of Emx2, En1 and Pax6. A gap between the Emx2 and En1
expression domains represents the anterior midbrain and P1/2 (brackets in EH). ...
Cited by 22 - Web Search - note.cellbio.duke.edu - cellbio.duke.edu - ncbi.nlm.nih.gov - all 5 versions »

Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK) - Full text - MIT Libraries
Y Xue, X Wang, Z Li, N Gotoh, D Chapman, EY … - Development, 2001 - dev.biologists.org
... Herrmann, 1991), Mox1 (Candia et al., 1992), HNF3β (Ang et al., 1993), fgf4, Tbx6
(Chapman et al., 1996), Otx2 (Simeone et al., 1993), En1 (Davis and Joyner ...
Cited by 6 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov