Analysis of a non-functional HNF-1 α(TCF 1) mutation in Japanese subjects with familial type 1 … - Full text - MIT Libraries
I Yoshiuchi, K Yamagata, M Yoshimoto, Q Zhu, Q … - Human Mutation, 2001 - doi.wiley.com
... Analysis of a Non-functional HNF-1α (TCF1) ... Takao Nammo, 1 Rikako Uenaka, 1
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Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription …
C Szpirer, M Riviere, R Cortese, T Nakamura, MQ … - Genomics, 1992 - ncbi.nlm.nih.gov
... rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and
HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and ...
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… targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2 - Full text - MIT Libraries
K Sigal, A ARONHEIM - Biochem. J, 2002 - biochemj.org
... Similarity between the binding motifs of c-Jun, ELK1\TCF1 (ternary complex factor
1) [7] and JNK inhibitory protein (JIP)-1 [8] is found in a consensus R ...
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Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line … - Full text - MIT Libraries
… Jun, GUO Shi Ying, Y Run Lin, Y Jun, WEN Chuan Jun … - Cell Research, 2004 - cell-research.com
... GUO, Run Lin YANG, Jun YUAN, Chuan Jun WEN, Kai Ya ZHOU, Chao Jun LI * ... TCF/LEF family
include LEF-1, TCF1, TCF3, TCF3 a, TCF4, which all contain DNA- binding ...
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Association of I27L polymorphism of hepatocyte nuclear factor-1 alpha gene with high-density … - Full text - MIT Libraries
N Babaya, H Ikegami, T Fujisawa, K Nojima, M Itoi- … - J Clin Endocrinol Metab, 2003 - jcem.endojournals.org
... Fujisawa , Koji Nojima , Michiko Itoi-Babaya , Kaori Inoue , Jun Nakura , Michiko ...
of the young; SNP, single-nucleotide polymorphism; TCF1, transcription factor ...
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Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development. - Full text - MIT Libraries
AS Nateri, B Spencer-Dene, A Behrens - Nature, 2005 - nature.com
... A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and ...
MTAP) in human colon carcinoma cells is regulated by TCF1/[beta]-catenin ...
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GEArray Q Series Mouse Signal Transduction in Cancer Gene Array: AR-SAMM-044
FG Grouping, A Pathway, C Cdk, E Pathway, B Bcl, H … - eurogentec.be
... Wnt Pathway: Abcb1a, Abcb1b, Bmp4, Ccnd1 (cyclin D1), Enpp2 (Autotaxin), Fosl1
(Fra-1), Idb2, Jun (c-jun), Mmp7, Myc (c-myc), Vegfa, Tcf1, Wisp1. Page 2. ...
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Interleukin 5, a T-cell-derived B-cell differentiation factor also induces cytotoxic T lymphocytes. - Full text - MIT Libraries
K Takatsu, Y Kikuchi, T Takahashi, T Honjo, M … - Proc Natl Acad Sci US A, 1987 - pubmedcentral.nih.gov
... vitro by nick translation with DNA polymerase I. J Mol Biol 1977 Jun 15;113 ... of IL
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The genes encoding the glutamate receptor subunits KA1 and KA2 (GRIK4 and GRIK5) are located on … - Full text - MIT Libraries
C Szpirer, M Molne, R Antonacci, NA Jenkins, P … - Proc Natl Acad Sci US A, 1994 - pubmedcentral.nih.gov
... and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of
the hepatocyte growth factor/scatter factor gene (HGF). Genomics 1992 Jun;13(2 ...
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Transcription factor expression in cell lines derived from natural killer-cell and natural killer- …
Y Matsuo, HG Drexler, A Harashima, A Okochi, N … - Hum Cell, 2004 - ncbi.nlm.nih.gov
2004 Jun;17(2):85-92. ... analyzed the expression of the following 13 TFs: AML1, CEBPA,
E2A, ETS1, GATA1, GATA2, GATA3, IKAROS, IRF1, PAX5, PU1, TBET and TCF1 in 7 ...
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Mutations in the hepatocyte nuclear factor-1 α gene in maturity-onset diabetes of the young(MODY 3) - Full text - MIT Libraries
K Yamagata, H Furuta, N Oda, PJ Kaisaki, S Menzel, … - Nature, 1996 - nature.com
... Yano † , Michelle M. Le Beau ‡ , Shirou Yamada ¶ , Hidekazu Nishigori ¶ , Jun Takeda ¶ ,
Stefan S ... factor-1 (HNF-1 , which is encoded by the gene TCF1). ...
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Activation of Wnt/b-Catenin/Tcf Signaling in Mouse Skin Carcinogenesis - Full text - MIT Libraries
N Bhatia, VS Spiegelman - MOLECULAR CARCINOGENESIS, 2005 - doi.wiley.com
... genes, c-myc and c-jun [28,29], revealed their upre- gulation in all tumors ... Immunoblot
analy- sis of Lef1, Tcf1, and Tcf3proteins revealed a very low levels of ...
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Dimethyl sulfoxide modulates NF- Kappa B and cytokine activation in lipopolysaccharide-treated … - Full text - MIT Libraries
KA Kelly, M Hill, K Youkhana, F Wanker, JM Gimble - Infection and Immunity, 1994 - pubmedcentral.nih.gov
... M, Ceredig R. Antioxidant treatment of thymic organ cultures decreases NF-kappa
B and TCF1(alpha) transcription factor ... J Exp Med 1976 Jun 1;143(6):1528–1533. ...
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Molecular causes of colon cancer - Full text - MIT Libraries
IM Oving, HC Clevers - European Journal of Clinical Investigation, 2002 - blackwell-synergy.com
... Reported target genes of the Wnt pathway include cyclin D1, c-myc, c-jun,
TCF1, metalloproteinase matrilysin and PPAR delta [21-24]. ...
Cited by 23 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Identification of mZnf8, a mouse Kruppel-like transcriptional repressor, as a novel nuclear … - Full text - MIT Libraries
K Jiao, Y Zhou, BL Hogan - Mol Cell Biol, 2002 - mcb.asm.org
... Many nuclear proteins such as c-Jun/c-Fos (48), SnoN (31), Ski (23, 32), TGF-ß induced
factor (TGIF) (43), Sp1 (7), Lef1/Tcf1 (18), and GATA3 (5) have been ...
Cited by 8 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

ß-Catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer - Full text - MIT Libraries
T Brabletz, A Jung, S Dag, F Hlubek, T Kirchner - Am. J. Pathol, 1999 - ajp.amjpathol.org
... m), and TCF(2.m)), leaving the other intact, or at both sites (TCF1.m/2 ... Recent data
demonstrating that ß-catenin/TCF also activates c-jun gene transcription 18 ...
Cited by 148 - Web Search - ajp.amjpathol.org - ncbi.nlm.nih.gov - all 4 versions »

Mutations in the hepatocyte nuclear factor-1α gene (MODY3) are not a major cause of early-onset non …
B Jochimsen… - springerlink.com
... Yamada · Tomoko Kohama Toshihiro Utsugi · Hiroyuki Shimizu · Toshiyuki Takeuchi
Jun Takeda ... encoding hepatocyte nuclear factor-1α (HNF-1α) (TCF1) are the ...
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Nature or nurture: an insightful illustration from a Chinese family with hepatocyte nuclear factor-1 … - Full text - MIT Libraries
MC Ng, JK Li, WY So, JA Critchley, CS Cockram, GI … - Diabetologia, 2000 - ncbi.nlm.nih.gov
Diabetologia. 2000 Jun;43(6):816-8 ... Insulin; TCF1 protein, human; hepatocyte nuclear
factor 1-beta. PMID: 10907130 [PubMed - indexed for MEDLINE]
Cited by 4 - Web Search - ncbi.nlm.nih.gov

The significance of the Wnt pathway in the pathology of human cancers
CS Lee - Pathology (April 2004) - dx.doi.org
... also can relay signals for the activation of Jun kinases. ... 1–3,17–19 The TCF/LEF family
contains at least four members in mammals; LEF, TCF1, TCF3 and TCF4. ...
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A simple test for the high-frequency P291fsinsC mutation in the HNF1 {alpha}/MODY3 gene - Full text - MIT Libraries
L Bjoerkhaug, O Soevik, GI Bell, PR Njoelstad, A … - Diabetologia, 2000 - ncbi.nlm.nih.gov
Diabetologia. 2000 Jun;43(6):818-9 ... genetics*. Substances: DNA Primers; DNA
Transposable Elements; Transcription Factors; TCF1 protein, human; ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Analysis of Transcription Factor Expression during Discrete Stages of Postnatal Thymocyte … - Full text - MIT Libraries
S Tabrizifard, A Olaru, J Plotkin, M Fallahi- … - The Journal of Immunology, 2004 - jimmunol.org
... The y-axis values represent relative fos or jun expression, compared with that of ...
2). In Tcf1 mutant mice (36), differentiation is impaired just before the DP ...
Cited by 1 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Maturity-onset diabetes of the young (MODY): the history of its dismemberment
P Froguel - Ann Endocrinol (Paris), 2003 - ncbi.nlm.nih.gov
Ann Endocrinol (Paris). 2003 Jun;64(3 Suppl):S12-6 ... TCF1 protein, human; HNF4A
protein, human; hepatocyte nuclear factor 1-beta; Glucokinase. ...
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Early-onset diabetes in the Mexican population: prevalence, genetic and metabolic features - Full text - MIT Libraries
T Factors - Rev Invest Clin, 2003 - ncbi.nlm.nih.gov
Rev Invest Clin. 2003 May-Jun;55(3):305-7 ... Substances: Phosphoproteins;
Transcription Factors; TCF1 protein, human; HNF4A protein, human; ...
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MODY in clinical practice. When and why to consider it?
G Velho - Ann Endocrinol (Paris), 2003 - ncbi.nlm.nih.gov
2003 Jun;64(3 Suppl):S17-21. ... TCF1 protein, human; hepatocyte nuclear factor 1-beta;
Glucokinase. PMID: 12910054 [PubMed - indexed for MEDLINE]
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Wnt-1 but not epidermal growth factor induces ß-catenin/T-cell factor-dependent transcription in … - Full text - MIT Libraries
T Mizushima, H Nakagawa, YG Kamberov, EL Wilder, … - Cancer Res, 2002 - cancerres.aacrjournals.org
... Western blotting with the anti-TCF1 antibody (top panel) and the anti-TCF4 antibody ...
inhibits apoptosis and that the inhibition is independent of the c-Jun-NH 2 ...
Cited by 15 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Transcriptional Profiles of Intestinal Tumors in Apc Min Mice are Unique from those of Embryonic … - Full text - MIT Libraries
T Reichling, KH Goss, DJ Carson, RW Holdcraft, C … - Cancer Research, 2005 - cancerres.aacrjournals.org
... with members of the T-cell factor (TCF) transcription factor family (TCF1, LEF1,
TCF3, and ... 43, WISP1, WISP2, fibronectin, Nr-CAM, AXIN2, fra-1, c-jun, and the ...
Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov

The significance of the Wnt pathway in the pathology of human cancers
CS Lee - Pathology (April 2004) - taylorandfrancis.metapress.com
... also can relay signals for the activation of Jun kinases. ... 1–3,17–19 The TCF/LEF family
contains at least four members in mammals; LEF, TCF1, TCF3 and TCF4. ...
Web Search - ingentaconnect.com

Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros … - Full text - MIT Libraries
C Orelio, E Dzierzak - Blood, 2003 - bloodjournal.org
... The expression of TCF1 and LEF1 corresponds to previous findings of Oosterwegel
et al. ... of TAK1 and is involved in nuclear factor- B (NF B) and Jun N-terminal ...
Cited by 1 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov

You Wnt some, you lose some: oncogenes in the Wnt signaling pathway
JH van Es, N Barker, H Clevers - Curr Opin Genet Dev, 2003 - microarray1.princeton.edu
... through small GTPases such as RhoA and Rac and activates c-Jun amino-terminal ... the
transcription of multiple Wnt target genes including c-Myc, Tcf1 and CyclinD1 ...
Cited by 34 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Gene expression in response to ionizing radiation: An overview of molecular features in …
M MORI, C DESAINTES - jbrha.com
... binding to their specific recognition sequences is also reported (AP1 for jun-fos
but ... Among the up-regulated genes are BTG3, BTG2, Lck, TCF1 whereas some down ...
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Search Article Keyword：
DX Cui, G Gomez, HJ Gao, L Zhang, LX Zhang, JR Xu, … - wjgnet.com
... 14-1219/R World J Gastroenterol 2005 March 7;11(9):1273-1282 A microarray-based
gastric carcinoma prewarning system Da-Xiang Cui, Li Zhang, Xiao-Jun Yan, Ling ...
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A microarray-based gastric carcinoma prewarning system
DX Cui, L Zhang, XJ Yan, LX Zhang, JR Xu, YH Guo, … - wjgnet.com
... Da-Xiang Cui, Li Zhang, Xiao-Jun Yan, Ling-Xia Zhang, Jun-Rong Xu, Yan-Hai Guo,
Gui-Qiu Jin, Giovani Gomez, Ding Li, Jin-Rong Zhao, Fen-Chan Han, Ju Zhang, Jia ...
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Gene Expression Profile Following Stable Expression of the Cellular Prion Protein
J Satoh, T Yamamura - Cellular and Molecular Neurobiology, 2004 - springerlink.com
... Expression of the Cellular Prion Protein Jun-ichi Satoh 1,2 and Takashi
Yamamura 1 Received April 20, 2004; accepted July 29, 2004 ...
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ORIGINAL ARTICLE Cytokines and Signal Transduction Pathways Mediated by Anthralin in Alopecia Areata …
L Tang, L Cao, S Pelech, H Lui, J Shapiro - Journal of Investigative Dermatology, 2003 - blackwell-synergy.com
... pathways (extracellular signal-regulated kinase pathway, c-Jun N-terminal ... Its downstream
substrate, -catenin, and transcriptional factor, TCF1 (Lef1), have ...
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Pin 1 regulates turnover and subcellular localization of< img border='0' src='/__chars/beta/black/ … - Full text - MIT Libraries
A Ryo, M Nakamura, G Wulf, YC Liou, KP Lu - Nature Cell Biology, 2001 - nature.com
... Synergy between tumor suppressor APC and the -catenin-Tcf4 target Tcf1. ... cancer and
potentiates the transcriptional activity of phosphorylated c-Jun towards the ...
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Naphthalene exposure: Effects on gene expression and proliferation in human cord blood cells
C Diodovich, I Malerba, G Bowe, F Acquati, MG … - Journal of Biochemical and Molecular Toxicology, 2003 - doi.wiley.com
... anti- rabbit IgG (Oncogene Research, diluted 1:3000 for BAX, BCL-2, and c-JUN) for
1 h ... TABLE 2. Summary of PCR Parameters for IL-8, FUS, TCF1, and GAPDH Genes ...
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Wnt signalling during limb development
VL Church, P Francis-West - Int J Dev Biol, 2002 - ijdb.ehu.es
... to Wnt signalling signals via the small GTPases Rho and Cdc42 to c-Jun N-terminal ...
of Wnts in limb outgrowth, gene-inactivation of both Lef1 and Tcf1, which are ...
Cited by 13 - View as HTML - Web Search - ncbi.nlm.nih.gov - ijdb.ehu.es - Get it from MIT Libraries

Short Communication
T Brabletz, A Jung, S Dag, F Hlubek, T Kirchner - American Journal of Pathology, 1999 - ajp.amjpathol.org
... However combined expression of both TCF4/ -catenin and Ets1, c-Jun/c-Fos led to
a ... TCF(1.m), and TCF(2.m)), leaving the other intact, or at both sites (TCF1.m/ 2 ...
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Gene expression profiling of tumours derived from rasV 12/E 1 A-transformed mouse embryonic … - Full text - MIT Libraries
S Vasseur, C Malicet, E Calvo, J Dagorn, J Iovanna - Molecular Cancer, 2005 - dx.doi.org
... finger C2H2 type, BTB (POZ) domain containing 14A, Jun oncogene, general ... dimerization
cofactor of hepatocyte nuclear factor 1 alpha (TCF1), chromobox homolog 3 ...
Web Search - pubmedcentral.nih.gov - molecular-cancer.com - citebase.eprints.org - all 9 versions »

BATF transgenic mice reveal a role for activator protein-1 in NKT cell development - Full text - MIT Libraries
KL Williams, AJ Zullo, MH Kaplan, RR Brutkiewicz, … - J. Immunol, 2003 - jimmunol.org
... transcription factors, including Ikaros, GATA-3, c-Myb, Ets1, TCF1, and members ... 1
transcription complexes function as dimers composed of the Fos, Jun, and ATF ...
Cited by 6 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 5 versions »

Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T- … - Full text - MIT Libraries
GN Marchenko, ND Marchenko, J Leng, AY Strongin - Biochem J, 2002 - biochemj.org
... Amersham (Piscataway, NJ, USA). Nuclear extracts from HeLa cells and purified
c-Jun protein were from Promega. All oligonucleotides used ...
Cited by 22 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Selected Papers on Zebrafish and Other Aquarium Fish Models
A Amsterdam, RM Nissen, Z Sun, EC Swindell, S … - dx.doi.org
... Two distinct teleost he- patocyte nuclear factor 1 genes, hnf1alpha/tcf1 and
hnf1beta/tcf2 ... Development Epub 2004 Jun 30; 2004 Aug; 131(15):3681–3692. ...
Web Search - liebertonline.com - liebertonline.com

Cytokines and Signal Transduction Pathways Mediated by Anthralin in Alopecia Areata-A¡ ected Dundee …
B Rats - ingentaconnect.com
... kinase pathways (extracellular signal-regulated kinase pathway, c-Jun N-terminal ...
downstream substrate, b-catenin, and transcriptional factor,TCF1 (Lef1), have ...
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Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome … - Full text - MIT Libraries
D Jung, M Fried, GA Kullak-Ublick - J Biol Chem, 2002 - jbc.org
... in the gene coding for hepatocyte nuclear factor 1 (HNF1 ) (encoded by Tcf1) have
no ... the rat ASBT gene promoter contains an AP-1 element that binds c-Jun and c ...
Cited by 12 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Tcf Binding Sequence and Position Determines b-Catenin and Lef-1 Responsiveness of MMP-7 Promoters - Full text - MIT Libraries
MD Gustavson, HC Crawford, B Fingleton, LM … - MOLECULAR CARCINOGENESIS, 2004 - doi.wiley.com
... of MMP-7 in the human embryonic kidney 293 (HEK293) cell line can be induced by
ectopic expression of Lef-1 and b-catenin in conjunction with PEA3 and c-Jun [33 ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov

Biochemical and kinetic characterization of the glucocorticoid-induced apoptosis of immature CD4 CD8 …
VN Ivanov, J Nikolic-Zugic - intimm.oupjournals.org
... also resulted in a remarkable and quick down-regulation of basal levels of other
TF, including NF-κB p50–p50, AP-1 (the upper band Jun–Fos complex; the ...
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New aspects of Wnt signaling pathways in higher vertebrates
J Huelsken, W Birchmeier - Curr. Opin. Genet. Dev, 2001 - bret.mc.vanderbilt.edu
... In the planar cell polarity pathway (orange in Figure 1), Wnt signaling activates
Jun-N-terminal ... This induction of FGF8 is dependent on LEF-1 and TCF1 and is ...
Cited by 145 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

Caught up in a Wnt storm: Wnt signaling in cancer
RH Giles, JH van Es, H Clevers - Biochim Biophys Acta, 2003 - rkblab.biochem.uci.edu
... Wnt pathways transduce Wnt signal to either the JNK (c-Jun N- terminal ... human
TCF/LEF family of transcription factors consists of four members: TCF1, LEF1, TCF3 ...
Cited by 133 - View as HTML - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression - Full text - MIT Libraries
J Zhao, R Pestell, JL Guan - Mol. Biol. Cell, 2001 - molbiolcell.org
... Jihe Zhao, * Richard Pestell, and Jun-Lin Guan * Dagger ... these elements deleted (Figure
5A). Figure 5B shows that deletion of the AP1, EtsA, EtsC, TCF1, or CRE ...
Cited by 21 - Web Search - intl.molbiolcell.org - pubmedcentral.nih.gov - genetics.biol.ttu.edu - all 7 versions »

Wnt Target Genes Identified by DNA Microarrays in Immature CD34 Thymocytes Regulate Proliferation … - Full text - MIT Libraries
FJT Staal, F Weerkamp, MRM Baert, CMM van den Burg … - The Journal of Immunology, 2004 - jimmunol.org
... small number ( 30) of genes changed expression, including several proliferation-
inducing transcription factors such as c-fos and c-jun, protein phosphatases ...
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