Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription …
C Szpirer, M Riviere, R Cortese, T Nakamura, MQ … - Genomics, 1992 - ncbi.nlm.nih.gov
... Gene Symbols: CEA; CEBP; CYP2B1; DBP; Dbp; EPO; Epo; GPI; HGF; IL6; LHB; MET; PAH;
PEPD; PGY1; PSBG1; Pah; Pgy1; RARG; Rar-g; Sp1; TCF1; TCF5; TCRB; Tcrb. Substances ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genomic organization and transcriptional analysis of the human L-glutaminase gene - Full text - MIT Libraries
C Perez-Gomez, JM Mates, PM Gomez-Fabre, A del … - Biochem. J, 2003 - ncbi.nlm.nih.gov
... DNA-Binding Proteins; Transcription Factor, Sp1; Transcription Factors; TCF1 protein,
human; hepatocyte nuclear factor 1-beta; hepatic leukemia factor; Glutaminase ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Characterization of the mouse lysosomal sialidase promoter. - Full text - MIT Libraries
MJ Champigny, M Johnson, SA Igdoura - Gene, 2003 - ncbi.nlm.nih.gov
... Recombinant Fusion Proteins; Repressor Proteins; Transcription Factor, Sp1;
Transcription Factors; TCF1 protein, human; hepatocyte nuclear ...
Web Search

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION - Full text - MIT Libraries
CT Kuo, JM Leiden - Annual Review of Immunology, 1999 - immunol.annualreviews.org
... of similar defects in thymocyte maturation in the LEF1/TCF1- and Sox4 ... domains of
several other mammalian transcription factors, including Sp1, BETB2, and Wilms ...
Cited by 125 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

Human HMG box transcription factor HBP 1: a role in hCD 2 LCR function - Full text - MIT Libraries
T Zhuma, R Tyrrell, B Sekkali, G Skavdis, A … - The EMBO Journal, 1999 - embojournal.npgjournals.com
... as follows: lanes 3 and 4, FT1.J; lanes 5 and 6, LEF1/TCF1; lanes 7 and 8, SOX4;
lanes 9 and 10, SRY; lanes 11 and 12, FT1.mB; lanes 13 and 14, SP1 (in 20 and ...
Cited by 21 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

Mouse prostasin gene structure, promoter analysis, and restricted expression in lung and kidney - Full text - MIT Libraries
GM Verghese, ZY Tong, V Bhagwandin, GH Caughey - Am J Respir Cell Mol Biol, 2003 - ajrcmb.org
... 1, ETF, N-Oct-3, HFH-8, TCF-1, and NF-AT sites in sequence 2; and Cdx-1, nuclear
factor (NF)- B, AP-2, Yi, TCF1, and SP1 sites in sequence 3 (data not shown). ...
Cited by 4 - Web Search - ajrcmb.atsjournals.org - intl-ajrcmb.atsjournals.org - ncbi.nlm.nih.gov - all 6 versions »

Development of artificial chimerical gene regulatory elements specific for cancer gene therapy - Full text - MIT Libraries
JHO SHIN, J YI, YJIN LEE, A KIM, M PARK, SH KIM, H … - ONCOLOGY REPORTS, 2003 - virology.med.uoc.gr
... The HK II promoter consists of CAAT elements, SP1 binding sites and glucose/insulin/
cAMP ... The 470 bp Tcf1 · enhancer is composed of a CpG island containing two ...
View as HTML - Web Search - 147.52.72.117 - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Sequence Note
C MONTAVON, L VERGNE, A BOURGEOIS, E MPOUDI-NGOLE, … - AIDS RESEARCH AND HUMAN RETROVIRUSES, 2002 - dx.doi.org
... All the previ- ously described sites in LTR, like TCF1-a, two NF-kB and three SP1,
the TATA box, and the poly(A) signal, were pres- ent in the newly described ...
Web Search - dx.doi.org - liebertonline.com - liebertonline.com

Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger … - Full text - MIT Libraries
ES Hwang, A Choi, IC Ho - The Journal of Immunology, 2002 - jimmunol.org
... competition assay, excessive unlabeled D-25 bp or SP1 oligonucleotides were ...
CCAAGCGAAGGCTGTCGGCAG-TAMRA, T cell-specific factor 1 (TCF1); 5'-CGCTGCCATCAACCAGATC ...
Cited by 6 - Web Search - jimmunol.org - jimmunol.org - ncbi.nlm.nih.gov - all 6 versions »

mBtd is required to maintain signaling during murine limb development - Full text - MIT Libraries
D Treichel, F Schoeck, H Jaeckle, P Gruss, A … - Genes & Development, 2003 - genesdev.org
... contains functional features of BTD, which are absent from SP1 and BTS1. ... Furthermore,
simultaneous inactivation of Lef1 and Tcf1, the mediators of the Wnt ...
Cited by 4 - Web Search - genesdev.org - pubmedcentral.nih.gov - dx.doi.org - all 7 versions »

CRF06-cpx: A New Circulating Recombinant Form of HIV-1 in West Africa Involving Subtypes A, G, K, …
C Montavon, C Toure-Kane, JN Nkengasong, L Vergne, … - JAIDS Journal of Acquired Immune Deficiency Syndromes, 2002 - jaids.org
... All previously described sites in LTR, TCF1-α, two NF-κB and three SP1, the TATA
box, and the poly-A signal were present in the newly described isolates. ...
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Identification of novel genes with somatic frameshift mutations within coding mononucleotide repeats …
U Potocnik, D Glavac, M Ravnik-Glavac - Genes Chromosomes Cancer, 2003 - doi.wiley.com
... genes in our study were CMRI-H and could thus possibly play a role in the development
of MSI-H tumors: TFE3 (9/38), TEF4 (12/38), RGS12 (11/38), and TCF1 (12/38 ...
Cited by 3 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Structural Organization and Promoter Analysis of Murine Heat Shock Transcription Factor-1 Gene - Full text - MIT Libraries
Y Zhang, S Koushik, R Dai, NF Mivechi - J Biol Chem, 1998 - jbc.org
... Furthermore, it is known that Sp1 elements can confer either negative or positive ...
times more efficient in stimulating the T cell receptor enhancer than TCF1. ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Strong expression of methylthioadenosine phosphorylase(MTAP) in human colon carcinoma cells is …
F Bataille, G Rogler, K Modes, I Poser, M … - Laboratory Investigation, 2004 - nature.com
... analysed the promoter region and identified con- sensus sites for binding of
TCF/LEF, Oct, Sp1, AP1, NF ... Conse- quently, expression of LEF1 and TCF1 was verified ...
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Research Article
F Bataille, G Rogler, K Modes, I Poser, M … - nature.com
... region and identified consensus sites for binding of TCF/LEF, Oct, Sp1, AP1,
NF-AT ... Consequently, expression of LEF1 and TCF1 was verified by RT-PCR and reporter ...
Web Search - nature.com

Expression of the mouse pre-T cell receptor alpha gene is controlled by an upstream region … - Full text - MIT Libraries
B Reizis, P Leder - J. Exp. Med, 1999 - intl.jem.org
... binding sites for T cell-specific transcription factors such as GATA3 or TCF1/LEF1. ...
Indeed, the bHLH proteins, YY1 and Sp1, are known to be involved in complex ...
Cited by 29 - Web Search - dx.doi.org - intl.jem.org - ncbi.nlm.nih.gov - all 5 versions »

Wnt-3A/b-catenin signaling induces transcription from the Lef-1 promoter - Full text - MIT Libraries
M Filali, N Cheng, D Abbott, V Leontiev, JF … - J Biol Chem, 2002 - elab.genetics.uiowa.edu
... start site ATG codon at 1. Numerous DNA binding domains for several transcription
factors, including Tcf1/LEF-1, Tcf11, NF-AT, and Sp1 were observed. ...
Cited by 10 - View as HTML - Web Search - jbc.org - jbc.org - ncbi.nlm.nih.gov - all 5 versions »

Mouseµ opioid receptor distal promoter transcriptional regulation by SOX proteins - Full text - MIT Libraries
CK Hwang, X Wu, G Wang, CS Kim, HH Loh - J. Biol. Chem, 2003 - jbc.org
... SOX5-BS12 (26); lane 6, TCF1 (T cell receptor chain enhancer) (27); lane 7, SRY
(sex region of the Y chromosome) (28). The nonspecific competitor Sp1 was used ...
Cited by 6 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

A conserved tissue-specific structure at a human T-cell receptor-chain core promoter - Full text - MIT Libraries
JP Halle, P Haus-Seuffert, C Woltering, G Stelzer, … - Mol. Cell. Biol, 1997 - mcb.asm.org
... Moderate ubiquitous activation is further induced by CREB/ATF and Sp1 factors through ...
family of high-mobility- group (HMG) box-containing factors TCF1 and LEF1 ...
Cited by 30 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

Identification of mZnf8, a mouse Kruppel-like transcriptional repressor, as a novel nuclear … - Full text - MIT Libraries
K Jiao, Y Zhou, BL Hogan - Mol Cell Biol, 2002 - mcb.asm.org
... Many nuclear proteins such as c-Jun/c-Fos (48), SnoN (31), Ski (23, 32), TGF-ß induced
factor (TGIF) (43), Sp1 (7), Lef1/Tcf1 (18), and GATA3 (5) have been ...
Cited by 8 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov - all 5 versions »

Germline alterations in the cyclooxygenase‐2 gene are not associated with the development of … - Full text - MIT Libraries
B Humar, O Giovanoli, A Wolf, M Attenhofer, I … - International Journal of Cancer, 2000 - doi.wiley.com
... upon various stimuli and contains majority of all regulatory elements so far identified,
including Sp1, Ap2, NF-IL6, NF- B, C/EBP, CRE, Tcf1, and Ets1 sites ...
Cited by 12 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Cdx1 Autoregulation Is Governed by a Novel Cdx1-LEF1 Transcription Complex - Full text - MIT Libraries
M Beland, N Pilon, M Houle, K Oh, JR Sylvestre, P … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... like phenotype and limb deficiency in Lef1 −/− Tcf1 −/− mice ... regulates c-kit
expression in hematopoietic cells through functional interaction with Sp1. ...
Cited by 2 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

The orphan nuclear receptor HNF4alpha determines PXR-and CAR-mediated xenobiotic induction of CYP3A4 - Full text - MIT Libraries
RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V … - Nat Med, 2003 - nature.com
... Hepatocyte nuclear factor-1α (HNF1α; TCF1) and liver receptor homolog-1 (LRH-1;
NR5A2) only modestly al- tered PXR-mediated activation of the CYP3A4 promoter ...
Cited by 55 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Structural and functional analysis of a promoter of the human granulin/epithelin gene - Full text - MIT Libraries
V Bhandari, R Daniel, PS Lim, A Bateman - Biochem. J, 1996 - biochemj.org
... the two genes in this region, such as the nuclear factors SP1 (nucleotides -87 ... 40],
as well as the tissue-specific transcription factors TCF1 (nucleotides -175 ...
Cited by 5 - Cached - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Genomic Organization of Mouse Gene zfp 162
C Wrehlke, WR Wiedemeyer, HP Schmitt-Wrede, A … - DNA and Cell Biology, 1999 - dx.doi.org
... The promoter exhibits the following mo- tifs: AP-2, CRE, Ets, GRE, HNF5, MRE,
SP-1, TRE, TCF1, and PU.1. The core promoter, from position 2 331 ...
Cited by 6 - Web Search - liebertonline.com - ncbi.nlm.nih.gov - all 4 versions » - Get it from MIT Libraries

Analysis of the Tcf-3 promoter during early development of Xenopus. - Full text - MIT Libraries
N Spieker, J Peterson, S Reneman, O Destree - DEVELOPMENTAL DYNAMICS, 2004 - doi.wiley.com
... Sp1-like proteins and Krüpel-like factors (KLFs) are highly related zinc-finger
proteins that regulate expression of a large number of genes that have GC-rich ...
Web Search - ncbi.nlm.nih.gov

SNAIL vs vitamin D receptor expression in colon cancer: therapeutics implications - Full text - MIT Libraries
MJ Larriba, A Munoz - British Journal of Cancer, 2005 - nature.com
... 3 inhibits the expression of -catenin target genes such as c-MYC, TCF1 or CD44 ...
regulation: Wilm's tumour suppressor, Zeb-1, Cdx-2 and Sp1 transcription factors ...
Web Search - nature.com - ncbi.nlm.nih.gov

Negative regulation of the Wnt–ß-catenin pathway by the transcriptional repressor HBP1 - Full text - MIT Libraries
EM Sampson, ZK Haque, MC Ku, SG Tevosian, C … - EMBO J, 2001 - embojournal.npgjournals.com
... Secondly, the TCF1 family member may be a candidate repressor. Gene knockout
studies of the TCF1 family member resulted in increased ...
Cited by 20 - Web Search - nature.com - emboj.org - pubmedcentral.nih.gov - all 7 versions »

Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta 7(CD 103) - Full text - MIT Libraries
PW Robinson, SJ Green, C Carter, J Coadwell, PJ … - Immunology, 2001 - blackwell-synergy.com
... contains a consensus initiator motif within close proximity of an SP1 site (Fig. ...
factors of particular significance to T cells, 26 eg GATA3, TCF1, LEF1 and Sox4 ...
Cited by 11 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

The C/EBP family of transcription factors in the liver and other organs - Full text - MIT Libraries
M Takiguchi - International Journal of Experimental Pathology, 1998 - blackwell-synergy.com
... 1995); C/EBP -glucocorticoid receptor (GR) ( Nishio et al. 1993); C/EBP
-Sp1 ( Lee et al. 1994, 1997b); C/EBP -Myb ( Mink et al. ...
Cited by 39 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma - Full text - MIT Libraries
XL Li, Y Eishi, YQ Bai, H Sakai, Y Akiyama, M Tani … - Int J Oncol, 2004 - 147.52.72.117
... It has been reported that MUC5AC was also up-regulated by Sp1, an ubiquitous ... H: Synergy
between tumor suppressor APC and the ß-catenin-Tcf4 target Tcf1. ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

A comprehensive review of genetic association studies
JN Hirschhorn, K Lohmueller, E Byrne, K Hirschhorn - Genet Med, 2002 - psych.umn.edu
... 37) PPP1R3 (298) RRAD (299) SLC2A1 (300) SLC2A2 (301) TCF1 (302) UCP3
(303) Gastroenterology Celiac disease CTLA4 (304) TNF (305) ...
Cited by 184 - View as HTML - Web Search - geneticsinmedicine.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

Full Text View - Full text - MIT Libraries
N Hsia, GA Cornwall - Biology of Reproduction - bioone.org
... the JAK/STAT pathway were present, as were CRSP2 (cofactor for Sp1 transactivation)
and ... factor 3γ (isgf3g), and hepatocyte nuclear factor 1α (TCF1) were also ...
Web Search

Mechanism of Chromatin Recognition and Transcriptional Regulation by LEF-1 and the Wnt/Wg-responsive …
A Tutter, GS Mc Alpine, KA Jones - Cold Spring Harb Symp Quant Biol, 1999 - dx.doi.org
... a novel multiprotein coactivator are required for synergistic activation by Sp1
and SREBP ... ergy between tumor suppressor APC and the β-catenin-Tcf4 target Tcf1. ...
Web Search - cshl-symposium.org - cshl-symposium.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

DNA Microarray Analysis of Region-Specific Gene Expression in the Mouse Epididymis - Full text - MIT Libraries
N Hsia, GA Cornwall - Biol Reprod, 2004 - biolreprod.org
... of the JAK/STAT pathway were present, as were CRSP2 (cofactor for Sp1 transactivation)
and ... factor 3 (isgf3g), and hepatocyte nuclear factor 1 (TCF1) were also ...
Cited by 6 - Web Search - bioone.org - dx.doi.org - ncbi.nlm.nih.gov - all 10 versions »

Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from …
EG Rizzatti, R Passetto, WT Anselmo-Lima, OK … - ingentaconnect.com
... signalling 12 4p16Æ3 10Æ2 NM_005077 TLE1 Transducin-like enhancer of split
1 (E(sp1) homolog, Drosophila) 9q21Æ32 9Æ9 NM_005086 ...
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DNA Microarray Analysis of Region-Specific Gene Expression 14 In the Mouse Epididymis 15 16 17
N Hsia, GA Cornwall - DNA - biolreprod.org
... pathway were present as well as CRSP2 (cofactor for Sp1 transactivation) and 380
Page 18. 18 ... factor 1 alpha (TCF1) were also detected in the epididymis. 389 ...
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Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T- … - Full text - MIT Libraries
GN Marchenko, ND Marchenko, J Leng, AY Strongin - Biochem J, 2002 - biochemj.org
... TATA, TATA-box; TIE, TGF-β inhibitory element; Sp1, transcription factor Sp-1;
OSE-2, osteoblast- specific element-2; TRF, octamer-binding protein; LBP-1 ...
Cited by 22 - View as HTML - Web Search - biochemj.org - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Full Text View - Full text - MIT Libraries
R Frank, HJ van Kranen, A van Schanke - Photochemistry and Photobiology - bioone.org
... of which (eg AP1, NFκB subunit p65, ATF2, Ets1 and Sp1) the cyclin ... Furthermore, PTEN
can counteract β-catenin in TCF1-mediated transcription of cyclin D1 (93 ...
Web Search - bioone.org

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
... repressor of CREG 1q24 E1A-stimulated genes NM_001881 cAMP responsive element modulator
CREM 10p12.1-p11.1 NM_004270 cofactor required for Sp1 CRSP9 5q33.3 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

Activity of hepatocyte nuclear factor 1a and hepatocyte nuclear factor 1b isoforms is differently … - Full text - MIT Libraries
V CARRIERE, M LACASA, M ROUSSET - Biochem. J, 2001 - biochemj.org
... HNF1b-C behaves as a transdominant repressor [5]. Invalidation of the TCF1 gene
(coding ... of the human Na + -glucose cotransporter gene, SGLT1, by HNF1 and SP1. ...
Cited by 6 - Cached - Web Search - biochemj.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Research Article - Full text - MIT Libraries
S Rutherford, GM Hampton, H F Frierson Jr, CA … - Laboratory Investigation, 2005 - nature.com
... with the consensus deletion loci identified in the LOH analysis of ACC (ANP32D,
HCCR1, SP1, DUSP6 and PRDM4 ... Bi-allelic inactivation of TCF1 in hepatic adenomas. ...
Cached - Web Search - nature.com

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors - Full text - MIT Libraries
F LOMBARDO, D KOMATSU, M HADJIARGYROU - Biochemistry, 1998 - pnas.org
... Home page, Nucleic Acids Res Home page MA Cohn, I. Hjelmso, LC Wu, P. Guldberg,
EM Lukanidin, and EM Tulchinsky Characterization of Sp1, AP-1, CBF and KRC ...
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Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypes - Full text - MIT Libraries
MA Montano, VA Novitsky, JT Blackard, NL Cho, DA … - J Virol, 1997 - jvi.asm.org
... Sequence variations within NF-AT, USF, TCF1 , TATA, and TAR as well as copy ... Contribution
of NF- B and Sp1 binding motifs to the repli- cative capacity of human ...
Cited by 52 - Web Search - hsph.harvard.edu - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 6 versions »

Common variations in noncoding regions of the human natriuretic peptide receptor A gene have … - Full text - MIT Libraries
J Knowles, L Erickson, V Guy, C Sigel, J Wilder, N … - Human Genetics, 2003 - springerlink.com
Page 1. Abstract Genetic susceptibility to common conditions, such as
essential hypertension and cardiac hypertrophy, is probably ...
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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors - Full text - MIT Libraries
ATLSTC Containing, RAMHCCI Expression - Biochemistry, 1998 - dx.doi.org
Vol. 95, Issue 20, 11590-11595, September 29, 1998. Biochemistry Transcriptional
repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors. ...
Web Search - pnas.org

Activity of hepatocyte nuclear factor 1α and hepatocyte nuclear factor 1β isoforms is differently … - Full text - MIT Libraries
M LACASA, M ROUSSET - Biochem. J, 2001 - biochemj.org
... C behaves as a transdominant repressor [5]. Invalidation of the TCF1 gene (coding ...
of the human Na + -glucose cotransporter gene, SGLT1, by HNF1 and SP1. Am. ...
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Biochemical and kinetic characterization of the glucocorticoid-induced apoptosis of immature CD4 CD8 …
VN Ivanov, J Nikolic-Zugic - intimm.oupjournals.org
Page 1. International Immunology, Vol. 10, No. 12, pp. 1807–1817 © 1998 Japanese
Society for Immunology Biochemical and kinetic characterization of ...
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Evaluation of the host transcriptional response to human cytomegalovirus infection - Full text - MIT Libraries
JF Challacombe, A Rechtsteiner, R Gottardo, LM … - Physiological Genomics, 2004 - physiolgenomics.physiology.org
Page 1. Evaluation of the host transcriptional response to human cytomegalovirus
infection Jean F. Challacombe 1 , Andreas Rechtsteiner ...
Web Search - stat.washington.edu - intl-physiolgenomics.physiology.org - ncbi.nlm.nih.gov - all 6 versions »

T-box genes in early embryogenesis - Full text - MIT Libraries
C Showell, O Binder, FL Conlon - Developmental Dynamics, 2004 - doi.wiley.com
Page 1. REVIEWS–A PEER REVIEWED FORUM T-box Genes in Early Embryogenesis
Chris Showell, Olav Binder, and Frank L. Conlon* The T ...
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