Sry and Sox9: mammalian testis-determining genes - Full text - MIT Libraries
P Koopman - Cell Mol Life Sci, 1999 - springerlink.com
... This observation placed SRY among a set of sequence-specific DNA-binding
transcription fac- tors that include TCF1 and LEF1 [12–14]. ...
Cited by 66 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Phosphorylation of an N-terminal Motif Enhances DNA-binding Activity of the Human SRY Protein - Full text - MIT Libraries
M Desclozeaux, F Poulat, PS Barbara, JP Capony, P … - Journal of Biological Chemistry, 1998 - jbc.org
... This subclass includes transcriptional regulators such as TCF1 (6) and
LEF-1 (7, 8), or diverse SOX (SRY-box related) proteins (9). ...
Cited by 23 - Web Search - jbc.org - ncbi.nlm.nih.gov

Cloning and characterisation of the Sry-related transcription factor gene Sox 8 - Full text - MIT Libraries
GE Schepers, M Bullejos, BM Hosking, P Koopman - Nucleic Acids Research, 2000 - nar.oupjournals.org
... discovery of the mammalian Y-linked sex-determining gene Sry, the Sry-related HMG ...
SOX group on the other hand contains the transcription factors TCF1 and LEF1 ...
Cited by 18 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Human sex reversal due to impaired nuclear localization of SRY - Full text - MIT Libraries
B Li, W Zhang, G Chan, A Jancso-Radek, S Liu, MA … - J. Biol. Chem, 2001 - jbc.org
... The upper group contains mammalian SRY sequences (h, human; m, mouse; b, bovine;
g ... lower group contains related sequences of Lef-1 and T-cell factor 1 (TCF1). ...
Cited by 10 - Web Search - jbc.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

SRY and architectural gene regulation: the kinetic stability of a bent protein-DNA complex can … - Full text - MIT Libraries
E Ukiyama, A Jancso-Radek, B Li, L Milos, W Zhang, … - Molecular Endocrinology, 2001 - mend.endojournals.org
... or Met (Fig. 1 B). Met occurs in Lef1/Tcf1 HMG boxes (12) where its role
is similar to that of I13 in SRY (10). The inserted side ...
Cited by 13 - Web Search - mgh.harvard.edu - dx.doi.org - ncbi.nlm.nih.gov - all 5 versions »

Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma - Full text - MIT Libraries
XL Li, Y Eishi, YQ Bai, H Sakai, Y Akiyama, M Tani … - Int J Oncol, 2004 - 147.52.72.117
... campomelic dysplasia are caused by mutations in and around the SRY-related gene ... H:
Synergy between tumor suppressor APC and the ß-catenin-Tcf4 target Tcf1. ...
Cited by 3 - View as HTML - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Sequence-specific High Mobility Group Box Factors Recognize 10-12-Base Pair Minor Groove Motifs - Full text - MIT Libraries
M van Beest, D Dooijes, M van de Wetering, S … - J Biol Chem, 2000 - jbc.org
... sequence-specific HMG domain family (2) as follows: the S. pombe mating type factor
MatMc (36), the lymphoid-specific factor Tcf1 (11), and the Sry-like factor ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov

Interactions between HMG boxes - Full text - MIT Libraries
S Taudte, H Xin, AJ Bell Jr, NR Kallenbach - Protein Engineering, 2001 - peds.oupjournals.org
... bind DNA with little apparent sequence specificity [HMG1, HMG2, UBF (upstream binding
factor)] while others recognize specific sequences (LEF1, SRY, TCF1). ...
Web Search - peds.oxfordjournals.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Human HMG box transcription factor HBP 1: a role in hCD 2 LCR function - Full text - MIT Libraries
T Zhuma, R Tyrrell, B Sekkali, G Skavdis, A … - The EMBO Journal, 1999 - embojournal.npgjournals.com
... FT1.J oligo with no protein; lanes 2-13 correspond to the following oligos incubated
with the HMG box: lanes 2-4, LEF1/TCF1, SOX4 and SRY, respectively; lanes 5 ...
Cited by 21 - Web Search - nature.com - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

The DNA bend angle and binding affinity of an HMG box increased by the presence of short terminal … - Full text - MIT Libraries
M Lnenicek-Allen, CM Read, C Crane-Robinson - Biophys. J, 2005 - nar.oupjournals.org
... The HMG box of human LEF-1 (hLEF-1, formerly TCF1 [alpha] ) has been expressed in ...
specific DNA sequence, eg the single boxes of LEF-1 ( 4 , 5 ) and SRY ( 6 , 7 ...
Cited by 19 - Web Search - nar.oupjournals.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Solution structure and backbone dynamics of the DNA-binding domain of mouse Sox-5 - Full text - MIT Libraries
PD Cary, CM Read, B Davis, PC Driscoll, C Crane- … - Protein Science, 2001 - protsci.highwire.org
... chain turning through 90°. Keywords: HMG box; LEF-1; TCF1 SRY; DNA bending.
Abbreviations: NOESY, nuclear Overhauser enhancement ...
Cited by 3 - Cached - Web Search - proteinscience.org - dx.doi.org - ncbi.nlm.nih.gov - all 8 versions »

Mutagenesis of the HMGB protein Cmb1 of Schizosaccharomyces pombe: effects on recognition of DNA …
C Kunz, K Zurbriggen, O Fleck - biochemj.org
... one HMG domain, like the transcription factors LEF-1 [13], SRY [14] and
TCF1 [15], which bind to specific nucleotide sequences. ...
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Mutagenesis of the HMGB (high-mobility group B) protein Cmb1 (cytosine-mismatch binding 1) of … - Full text - MIT Libraries
K Christophe, K ZURBRIGGEN, O FLECK - Biochem. J, 2003 - biochemj.org
... of proteins containing one HMG domain, such as the transcription factors LEF-1
[13], SRY [14] and TCF1 [15], which bind to specific nucleotide sequences. ...
View as HTML - Web Search - biochemj.org - dx.doi.org

High-mobility group box 1 protein(HMGB 1): nuclear weapon in the immune arsenal - Full text - MIT Libraries
MT Lotze, KJ Tracey - Nature Reviews Immunology, 2005 - nature.com
... TCF1 (T-cell factor 1) and LEF1 (lymphoid-enhancer-binding factor 1),the fungal
mating genes mat-Mcand MATa1,and the mammalian sex-determining gene SRY (sex ...
Web Search - ncbi.nlm.nih.gov

Cellular and molecular pathways regulating mammalian sex determination - Full text - MIT Libraries
C Tilmann, B Capel - Recent Prog. Horm. Res, 2002 - note.cellbio.duke.edu
... Other members of this family include Tcf1 (T-cell factor 1), Tcf4, Lef1 (lymphoid
enhancer binding factor), and Sox (Sry-related box) genes. ...
Cited by 22 - View as HTML - Web Search - cellbio.duke.edu - rphr.endojournals.org - ncbi.nlm.nih.gov

Diversification pattern of the HMG and SOX family members during evolution - Full text - MIT Libraries
S Soullier, P Jay, F Poulat, JM Vanacker, P Berta, … - J Mol Evol, 1999 - springerlink.com
... such as the T-cell transcription factors TCF1 and LEF1, the mating-type proteins
of several fungi, the mammalian male sex-determining factor SRY, and the ...
Cited by 26 - Web Search - ncbi.nlm.nih.gov

Cdx1 Autoregulation Is Governed by a Novel Cdx1-LEF1 Transcription Complex - Full text - MIT Libraries
M Beland, N Pilon, M Houle, K Oh, JR Sylvestre, P … - Mol Cell Biol, 2004 - pubmedcentral.nih.gov
... LEF1 and TCF1 as well as Cdx2 are also involved in events related to ... potentially
relevant HMG box-Cdx1 interactions, we investigated the ability of Sry HMG box ...
Cited by 2 - Web Search - mcb.asm.org - ncbi.nlm.nih.gov

Mouseµ opioid receptor distal promoter transcriptional regulation by SOX proteins - Full text - MIT Libraries
CK Hwang, X Wu, G Wang, CS Kim, HH Loh - J. Biol. Chem, 2003 - jbc.org
... related binding sequences for T cell factor (TCF)-MW56 (T cell receptor) (26),
SOX5-BS12 (26), TCF1 (T cell receptor chain enhancer) (27), and SRY (sex region ...
Cited by 6 - Web Search - dx.doi.org - jbc.org - ncbi.nlm.nih.gov

The high mobility group transcription factor, SOX 4, transactivates the human CD 2 enhancer. - Full text - MIT Libraries
D Wotton, RA Lake, CJ Farr, MJ Owen - J Biol Chem, 1995 - jbc.org
... elements shows homology to the canonical HMG site bound by the T cell-specific
transcription factors, TCF1 and TCF1- , and the sex-determining gene, SRY(8, 22 ...
Cited by 11 - Web Search - jbc.org - ncbi.nlm.nih.gov

Molecular Mechanisms Regulating Hair Follicle Development - Full text - MIT Libraries
SE Millar - Journal of Investigative Dermatology, 2002 - blackwell-synergy.com
... It is likely that further analysis of Tcf1 and Tcf4 expression patterns in skin ... A
member of the Sry-type high mobility group box (SOX) transcription factor ...
Cited by 61 - Web Search - jidonline.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

A Direct{beta}-Catenin-independent Interaction between Androgen Receptor and T Cell Factor 4 - Full text - MIT Libraries
AL Amir, M Barua, NC McKnight, S Cheng, X Yuan, SP … - J Biol Chem, 2003 - jbc.org
... SRY interaction was direct and mediated by the AR DBD and the HMG domain of SRY. ...
Tcf4 and the other human Tcf proteins (Tcf1, Tcf2/Lef1, and Tcf3) are sequence ...
Cited by 9 - Web Search - jbc.org - ncbi.nlm.nih.gov

RESEARCH ARTICLES Structure Prediction of a Complex Between the Chromosomal Protein HMG-D and DNA - Full text - MIT Libraries
A Balaeff, MEA Churchill, K Schulten - PROTEINS: Structure, Function, and Genetics, 1998 - doi.wiley.com
... features seen in the NMR structures of the sequence-specific HMG- domain-DNA complexes,
lymphoid enhancer factor 1 (LEF-1) and testis determining factor (SRY). ...
Cited by 15 - Web Search - doi.wiley.com - ks.uiuc.edu - ncbi.nlm.nih.gov - all 5 versions »

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION - Full text - MIT Libraries
CT Kuo, JM Leiden - Annual Review of Immunology, 1999 - immunol.annualreviews.org
... It was first identified using a low-stringency PCR screen of mouse T cell RNA and
is highly related to TCF1, LEF1, and the sex-determining gene, Sry (81). ...
Cited by 125 - Web Search - immunol.annualreviews.org - ncbi.nlm.nih.gov

Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression
E Bandres, E Andion, A Escalada, B Honorato, V … - Journal of Neuro-Oncology, 2005 - springerlink.com
... SMARCD1 IKBKG SMARCD1 BICD1 EZH2 DDX16 GCMA FOXJ1 HOXA4 CDX4 LMX1B IER3 MYF3 MYOG
POLR2E NPAS1 TCF1 PBX2 RENT1 NKX2B SRY TCF21 TLE3 195 Page 8. ...
Web Search - ingentaconnect.com

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
Page 1. Molecular Vision 2004; 10:163-76 <http://www.molvis.org/molvis/v10/a22>
Received 3 October 2003 | Accepted 16 March 2004 | Published 22 March 2004 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

Genetic dissection of mammalian fertility pathways - Full text - MIT Libraries
MM Matzuk, DJ Lamb - Nature Cell Biology, 2002 - mrg.genetics.washington.edu
... and infertility revealed that many XX males have translocations of a small piece
of the Y chromosome,so that the sex-determining region Y gene (SRY) results in ...
Cited by 60 - View as HTML - Web Search - nature.com - tu-cottbus.de - ncbi.nlm.nih.gov - all 5 versions »

The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation - Full text - MIT Libraries
C Zhang, T Basta, ED Jensen, MW Klymkowsky - Development, 2003 - dev.biologists.org
... The HMG boxes of SOX proteins share at least 50% identity with the HMG
box of the mammalian male sex determining polypeptide SRY. ...
Cited by 5 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from …
EG Rizzatti, R Passetto, WT Anselmo-Lima, OK … - ingentaconnect.com
... 3q13Æ2 6Æ8 AB028641 SOX11 SRY (sex-determining region Y)-box 11 2p25 6Æ8 ... 1q22-q23
)29Æ5 NM_003107 SOX4 SRY (sex-determining region Y)-box 4 6p22Æ3 )22Æ3 ...
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of Biology - Full text - MIT Libraries
T Okubo, BLM Hogan - Journal of Biology, 2004 - biomedcentral.com
... Lef1 Tcf1 Tcf4 ... 1424903_at Smcy selected mouse cDNA on the Y Mm.1064 AF127244 10.8
0.006 1451835_at Sox21 SRY-box containing gene 21 Mm.70950 AY069926 8.9 0.001 ...
View as HTML - Web Search - bmc.ub.uni-potsdam.de - cellbio.duke.edu - genetics.wisc.edu - all 5 versions »

Activation and Repression of Wingless/Wnt Target Genes by the TCF/LEF-1 Family of Transcription …
HC KORSWAGEN, HC CLEVERS - Cold Spring Harbor Symposia on Quantitative Biology, 1999 - dx.doi.org
... This type of DNA- binding domain is also found in the SOX/SRY family of ... Wnt3a –/–
-like phenotype and limb deficiency in Lef1(–/–)Tcf1(–/–) mice. ...
Cited by 12 - Web Search - cshl-symposium.org - cshl-symposium.org - ncbi.nlm.nih.gov - Get it from MIT Libraries

All Tcf HMG box transcription factors interact with Groucho-related co-repressors - Full text - MIT Libraries
H Brantjes, J Roose, M van De Wetering, H Clevers - Nucleic Acids Research, 2001 - nar.oupjournals.org
... H. (1999) Synergy between tumor suppressor APC and the ß-catenin-Tcf4 target Tcf1. ...
J. and Goodfellow,P. (1993) SOX3 is an X-linked gene related to SRY. Hum. ...
Cited by 56 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

Isolation of a mammalian homologue of a fission yeast differentiation regulator - Full text - MIT Libraries
H Yamamoto, K Tsukahara, Y Kanaoka, S Jinno, H … - Mol. Cell. Biol, 1999 - mcb.asm.org
... Sry has been proposed to act as a transcriptional regulator, which recognizes specific ...
On the other hand, in Tcf1 / mouse, T-cell differentiation is blocked at ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov

AND-1, a natural chimeric DNA-binding protein, combines an HMG-box with regulatory WD-repeats - Full text - MIT Libraries
A Kohler, MS Schmidt-Zachmann, WW Franke - J. Cell Sci, 1997 - jcs.biologists.org
Page 1. INTRODUCTION The nucleoplasm is a large subcellular compartement
contain- ing a pool of soluble proteins, protein complexes ...
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List of Research Projects
MPMC GRN - cco.caltech.edu
... Deletion of the three Tcf1-binding sites also decreased the promoter activity. ... Lynne
Angerer* S. purparatus SoxB1 (SpSoxB1), a member of Sox (SRY-related box ...
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Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted … - Full text - MIT Libraries
X Ma, T Husain, H Peng, S Lin, O Mironenko, N Maun … - Blood, 2002 - bloodjournal.org
... Sox4 Important for very early B-cell differentiation 2.1 1.1 2.7 0.26 Sox5 SRY-box
containing gene 5 — 3.1 0.22 Tal1 T-cell acute lymphocytic leukemia 1 ...
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Regulation der BOB. 1/OBF. 1-Expression und der BOB. 1/OBF. 1-Proteinstabilitaet
J Boehm - opus.bibliothek.uni-wuerzburg.de
... kloniert. Die Analyse der Promotor-Sequenz ergab Bindungsstellen für die
Transkriptionsfaktoren CREB, NF-AT und ein SRY-Motiv. In ...
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Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells - Full text - MIT Libraries
J Houldsworth, SC Heath, GJ Bosl, L Studer, RS … - Cell Growth Differ, 2002 - cgd.aacrjournals.org
... expressed such as the RNA-binding protein musashi (MSI1) and the SRY-related high ...
H. Synergy between tumor suppressor APC and the ß-catenin-Tcf4 target Tcf1. ...
Cited by 6 - Web Search - cgd.aacrjournals.org - ncbi.nlm.nih.gov

Ligand-dependent inhibition of b-catenin/TCF signaling by androgen receptor - Full text - MIT Libraries
DR Chesire, WB Isaacs - Oncogene, 2002 - nature.com
... Most CaP cell lines in culture express TCF4, but little or none of the three other
TCF/LEF transcription factor family members (LEF, TCF1, TCF3; unpub- lished ...
Cited by 19 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

Pin 1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction … - Full text - MIT Libraries
A Ryo, M Nakamura, G Wulf, YC Liou, KP Lu - Nature Cell Biology, 2001 - nature.com
... gsk CD97 α-2-actinin BIP/GRP78 Tu translation-elongation factor (p43) PPAR-delta*
Platelet-activating factor acetylhydrolase Ib- γ SRY (sex-determination Y ...
Cited by 58 - Web Search - research.caregroup.org - research.bidmc.harvard.edu - ncbi.nlm.nih.gov - all 7 versions »

Meta-analysis of indels causing human genetic disease: mechanisms of mutagenesis and the role of … - Full text - MIT Libraries
NA Chuzhanova, EJ Anassis, EV Ball, M Krawczak, DN … - Human Mutation, 2003 - doi.wiley.com
Page 1. RESEARCH ARTICLE Meta-Analysis of Indels Causing Human Genetic Disease:
Mechanisms of Mutagenesis and the Role of Local DNA Sequence Complexity ...
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Lymphoid enhancer factor/T cell factor expression in colorectal cancer
ML Waterman - Cancer and Metastasis Reviews, 2004 - springerlink.com
Page 1. Cancer and Metastasis Reviews 23: 41–52, 2004. # 2004 Kluwer Academic
Publishers. Manufactured in The Netherlands. Lymphoid ...
Cited by 1 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Multistep tumorigenesis of medullary thyroid carcinoma in man and transgenic mouse models
DS Acton - 2005 - igitur-archive.library.uu.nl
... gene (EDNRB), glial-cell-line-derived neurotrophic factor (GDNF), endothelin converting
enzyme (ECE1) and the gene encoding the Sry-related transcription ...
View as HTML - Web Search - dspace.library.uu.nl - dspace.library.uu.nl

Discrimination of Vanadium from Zinc Using Gene Profiling in Human Bronchial Epithelial Cells
Z Li, J Stonehuerner, RB Devlin, YCT Huang - ehp.niehs.nih.gov
Page 1. Discrimination of Vanadium from Zinc Using Gene Profiling in Human Bronchial
Epithelial Cells Zhuowei Li, Jackie Stonehuerner, Robert B. Devlin, ...
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[BOOK] Essential developmental biology
JMW Slack - 2000 - print.google.com
Page 1. Essential Developmental Biology JMW Slack DepartmentofBiologyand
Biochemistry UniversityofBath Blackwell S Publishing Page 2. ...
Cited by 12 - Web Search - Get it from MIT Libraries - Library Search

Aus dem Institut fuer Tieranatomie der Ludwig-Maximilian-Universitaet Muenchen Lehrstuhl fuer …
I Schroll - edoc.ub.uni-muenchen.de
... 135 24. Sox (Sry-type high-mobility group box protein) 137 25. ... Shh Sonic hedgehog
Sox Sry-type high-mobility group box protein TGF Transforming Growth Factor ...
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TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein … - Full text - MIT Libraries
S Spicuglia, D Payet, RK Tripathi, P Rameil, C … - The EMBO Journal, 2000 - embojournal.npgjournals.com
... a notion that is consistent with the defects in expression and rearrangement of
the TCR locus in double knock-out Lef1 –/– Tcf1 –/– thymocytes (Okamura ...
Cited by 14 - Web Search - nature.com - emboj.org - ciml.univ-mrs.fr - all 8 versions »

PATTERNING MECHANISMS CONTROLLING VERTEBRATE LIMB DEVELOPMENT - Full text - MIT Libraries
J Capdevila, JCI Belmonte - Annual Review of Cell and Developmental Biology, 2001 - intl-cellbio.annualreviews.org
Annual Reviews tagline graphic, ...
Cited by 99 - Web Search - astro.annualreviews.org - lifesci.sussex.ac.uk - ncbi.nlm.nih.gov - all 6 versions »

EVOLUTION OF COMPONENTS OF GENE REGULATION IN DROSOPHILA AND MAMMALS
ET Dermitzakis - etda.libraries.psu.edu
Page 1. The Pennsylvania State University The Graduate School The Eberly College
of Science EVOLUTION OF COMPONENTS OF GENE REGULATION IN DROSOPHILA AND MAMMALS ...
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Liver-Enriched Transcription Factors in Liver Function and Development. Part II: the C/EBPs and D … - Full text - MIT Libraries
H Schrem, J Klempnauer, J Borlak - Pharmacol Rev, 2004 - pharmrev.org
Institution: Google Indexer Sign In as Member/Non-Member. 0031-6997/
04/5602-291-330$7.00 Pharmacol Rev 56:291-330, 2004 ...
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JBC Papers in Press. Published on October 24, 2001 as Manuscript M107795200
C Kumar-Sinha, S Varambally, A Sreekumar, AM … - jbc.org
Page 1. Molecular Cross-Talk Between the TRAIL and Interferon Signaling Pathways
Chandan Kumar-Sinha, Sooryanarayana Varambally, Arun ...
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