A role for the Msx-1 homeodomain in transcriptional regulation: Residues in the N-terminal arm … - Full text - MIT Libraries
H Zhang, KM Catron, C Abate-Shen - Biochemistry, 1996 - dx.doi.org
... the Smad Corepressor TGIF Is Disrupted by a Holoprosencephaly Mutation in TGIF J.
Biol ... Sarapura, HL Strouth, DF Gordon, WM Wood, and EC Ridgway Msx1 Is Present ...
Cited by 37 - Web Search - pnas.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

GENETICS OF CRANIOFACIAL DEVELOPMENT AND MALFORMATION - Full text - MIT Libraries
AOM Wilkie, GM Morriss-Kay - Nature Reviews Genetics, 2001 - nature.com
... 40. Gripp, KW et al. Mutations in TGIF cause holoprosencephaly and link NODAL
signalling to human neural axis determination. Nature Genet. 25, 205-208 (2000). ...
Cited by 63 - Web Search - nature.com - ncbi.nlm.nih.gov

Mouse models of holoprosencephaly
M Hayhurst, SK McConnell - Curr Opin Neurol, 2003 - co-neurology.com
... The transcriptional co-repressor tumor growth interacting factor (TGIF) [12] represses ...
However, Msx1 (a downstream target of BMPs) shows an expanded expression ...
Cited by 4 - Web Search - stanford.edu - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in … - Full text - MIT Libraries
S Chiba, K Takeshita, Y Imai, K Kumano, M Kurokawa … - Proc Natl Acad Sci US A, 2003 - pubmedcentral.nih.gov
... the transcriptional activation by BMPs (6). A ubiquitously expressed homeoprotein
TGIF binds to Smad3 ... It is known that DLX1 and DLX2, as well as MSX1 and MSX2 ...
Web Search - dx.doi.org - pnas.org - ncbi.nlm.nih.gov - all 6 versions »

Homeodomain Sequences
SD Subsets, V Plots - pnas.org
... LMX1, MBH1, MEIS1, Meis2, Meis3, Mix.1, Mix.2, Mix.3, Mix.4, MOX1, MOX2, MSX1,
Msx-2 ... Prop-1, PROX1, Psx, Ptx-1, Rx1, S8, SIX1, Six2, Spx1, Tcl-3, TGIF, Tlx2, Tst ...
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Repression of Bone Morphogenetic Protein and Activin-inducible Transcription by Evi-1 - Full text - MIT Libraries
T Alliston, TC Ko, Y Cao, YY Liang, XH Feng, C … - J. Biol. Chem, 2005 - jbc.org
... that enhance the transcription response or corepressors, including c-Ski, TGIF,
SIP1, SNIP1 ... were as described (41), with the addition of the Msx1 primers Msx1-U ...
Web Search - jbc.org - ncbi.nlm.nih.gov

Molecular evolution of the homeodomain family of transcription factors - Full text - MIT Libraries
S Banerjee-Basu, AD Baxevanis - Nucleic Acids Research, 2001 - nar.oupjournals.org
... 2). Furthermore, MSX1 is closely linked to two NK class members (HMX1 and ... Another
atypical class member TGIF is expressed during early brain development in ...
Cited by 25 - Web Search - pubmedcentral.nih.gov - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions »

Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle … - Full text - MIT Libraries
RSV Chadalavada, J Houldsworth, AB Olshen, GJ Bosl … - Functional & Integrative Genomics, 2005 - springerlink.com
... GPR39 STC1 PLP1 HXB CEP3 ARHE LOC51580 MID1 ABLIM ENC1 KAL1 CAV1 TGIF VSNL1 PEA15 ...
SIAT1 PAK1 OLFM1 ZIC3 TMSNB EPHB6 PTN EED MYO10 GJA1 NEFL ADORA1 MSX1 ID3 ID1 ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

Original Research Report
ESC Differentiation - dx.doi.org
... HIPK2; HN1; HOXB2; ID3; IRX2; IRX3; IRX4; LASP1; LLGL2; MILD1; MSX1; MSX2; NEUROG1 ...
SOX13; SOX17; SOX18; SOX2; SOX20; SOX3; SOX4; SOX5; SOX6; TGIF; TGIF2; weak ...
Web Search - liebertonline.com - liebertonline.com

The Spectrum of Orofacial Clefting.
BLMD Eppley, JAMD van Aalst, A Robey, RJMD Havlik, … - Plastic and Reconstructive Surgery, 2005 - plasreconsurg.com
... incidence of orofacial clefting.39 Infants with allelic variants at the MSX1 site
born ... These include sonic hedgehog (SHH),60 TGIF,61 SIX3,62 ZIC2,63 and PTCH ...
Web Search - plasreconsurg.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD 13 … - Full text - MIT Libraries
P Debeer, C Bacchelli, PJ Scambler, L De Smet, JP … - Journal of Medical Genetics, 2002 - dx.doi.org
... of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel ...
A human MSX1 homeodomain missense mutation causes selective tooth agenesis. ...
Cited by 9 - Web Search - jmg.bmjjournals.com - jmg.bmjjournals.com - ncbi.nlm.nih.gov - all 5 versions »

Homeodomain revisited: a lesson from disease-causing mutations - Full text - MIT Libraries
YI Chi - Human Genetics, 2005 - springerlink.com
... Hypodontia MSX1 142983 Homeodomain (166–225) R196P PS/DB ... PS(?) PS PS/DB
Holoprosencephaly TGIF 602630 Homeodomain (35–97) P63R R90C PS/DB DB ...
Web Search - ncbi.nlm.nih.gov

Septo-Optic Dysplasia and Related Malformations
MT Dattani - Hypothalamic-pituitary development: genetic and clinical …, 2001 - content.karger.com
... PAX3 (Waardenberg syndrome type I), PAX6 (anir- idia), MSX1 (selective tooth ... of
holoprosencephaly – these are Sonic Hedgehog (SHH), ZIC2, TGIF and SIX3. ...
Cited by 2 - Web Search - content.karger.com

Status of the Human Malformation Map: 2002
JC CAREY, DH VISKOCHIL - American Journal of Medical Genetics (Semin. Med. Genet.), 2002 - doi.wiley.com
... Holoprosencephaly-4 142946 602630 18p11 TGIF TG-interacting factor ... Hypodontia with
orofacial cleft 106600 142983 4p16.1 MSX1 Muscle segment homeo box ...
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Perspectives on Growth Factors and Orofacial Development
RM Greene, MM Pisano - Current Pharmaceutical Design, 2004 - ingentaconnect.com
... Thus, induction of TGFß target genes represents a balance between recruitment of
activators (such as CBP and p300) and repressors (such as TGIF, c-Ski and SnoN ...
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Molecular aspects of vertebrate retinal development
SS Zhang, XY Fu, CJ Barnstable - Mol. Neurobiol, 2002 - biomed.humanapress.com
... Six6 (Optx2) TF – (67) Hesx1 TF y (68) TGIF TF – (69) FGF8 GF – (17) Formation of
optic cup ... Lhx2 TF y (23) BF-1 TF y (71) Msx1 TF y (24) Msx2 TF y (25) ...
Cited by 9 - Web Search - neurosci.humanapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 6 versions » - Get it from MIT Libraries

Malformations of the Craniofacial Region: Evolutionary, Embryonic, Genetic, and Clinical …
M MICHAEL COHEN JR - American Journal of Medical Genetics (Semin. Med. Genet.), 2002 - doi.wiley.com
... Hypodontia/clefting 4p16 MSX1 Mucopolysaccharidosis IH 4p16.3 IDA ...
Holoprosencephaly 18p11.3 TGIF Peutz-Jeghers syndrome 19p13.3 STK11 ...
Cited by 12 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Microarray analysis of gene expression in human donor sclera - Full text - MIT Libraries
TL Young, GS Scavello, PC Paluru, JD Choi, EF … - Mol Vis, 2004 - molvis.org
... musculin (activated B-cell MSC 8q21 factor-1) NM_078629 male-specific lethal 3-like
1 MSL3L1 Xp22.3 (Drosophila) NM_002448 msh homeo box homolog 1 MSX1 4p16.3 ...
Cited by 3 - View as HTML - Web Search - molvis.org - scavello.net - ncbi.nlm.nih.gov

Smad4 and β-catenin co-activators functionally interact with Lef1to regulate graded
SM Hussein, EK Duff, C Sirard - jbc.org
... its interaction with the homeodomain protein TGIF (8) to either induce or repress ...
Msx1 in the ectoderm of Xenopus embryos inhibits neural and promotes epidermal ...
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Epithelial-Mesenchymal Transformation during Craniofacial Development - Full text - MIT Libraries
P Kang, KKH Svoboda - J Dent Res, 2005 - jdr.iadrjournals.org
... Msx1 was identified as having a critical role in mediating epithelial-mesenchymal
interactions during craniofacial bone and tooth development. ...
Web Search - jdr.iadrjournals.org

Smad 4 and{beta}-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to … - Full text - MIT Libraries
SM Hussein, EK Duff, C Sirard - J Biol Chem, 2003 - jbc.org
... deacetylase HDAC-1 via its interaction with the homeodomain protein TGIF (8) to ... genes
appear to mediate this response, because overexpression of Msx1 in the ...
Cited by 13 - Web Search - jbc.org - ncbi.nlm.nih.gov

A novel homeobox gene mediates the Dpp signal to establish functional specificity within target … - Full text - MIT Libraries
H Nakagoshi, M Hoshi, Y Nabeshima, F Matsuzaki - Genes Dev, 1998 - genesdev.org
... 1991 ), Bagpipe (d-NK3), d-NK2 (Kim and Nirenberg 1989 ), h-Msx1 (Hox-7 ... Analysis
of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a ...
Cited by 16 - Web Search - genesdev.org - pubmedcentral.nih.gov - ncbi.nlm.nih.gov - all 7 versions »

The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and … - Full text - MIT Libraries
J Gomez-Skarmeta, E de la Calle-Mustienes, J … - Development, 2001 - dev.biologists.org
Page 1. INTRODUCTION Vertebrate neural tissue is generated by an inductive
process. In Xenopus embryos, the Spemann organizer, which ...
Cited by 27 - Web Search - dev.biologists.org - ncbi.nlm.nih.gov

Limb anomalies and craniofacial syndromes II. Gene regulation of morphogenetic and dysmorphogenetic …
FN Synodinos, MJ Papagrigorakis - grortho.gr
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59 ∞ӈ̷ϛ˜ ÙˆÓ ¿ÎÚˆÓ Î·È Û‡Ó‰ÚÔÌ· ÙÔ ...
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TGF-ß SIGNAL TRANSDUCTION IN ORO-FACIAL HEALTH AND NON-MALIGNANT DISEASE (PART I)
SS Prime, M Pring, M Davies, IC Paterson - crobm.iadrjournals.org
... In contrast, repression of Smad-activated transcription occurs through the action
of co-repressors such as TGIF (Wotton et al., 1999) and the proto-oncogenes ...
Web Search - crobm.iadrjournals.org

The TGF-β Family: Signaling Pathways, Developmental Roles, and Tumor Suppressor Activities
AN Johnson, SJ Newfeld - TheScientificWorldJOURNAL, 2002 - thescientificworld.com
... The homeodomain protein TGIF[105,106], the oncogene c-ski, and the related protein
SnoN bind active Smad2/Smad4 and Smad3/Smad4 ... Msx1 Frog Blastomere 239 ...
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