Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes … - Full text - MIT Libraries
H Yoon, S Liyanarachchi, FA Wright, R Davuluri, JC … - Bioinformatics, 2005 - dx.doi.org
... a strategy to demonstrate that many genes are affected by TP53 gene dosage ... Ziegelbauer,
B. Stuart, B. Wahle, W. Bomann, and HJ Ahr Characteristic Expression ...
Cited by 19 - Web Search - pnas.org - pubmedcentral.nih.gov - osuccc.osu.edu - all 7 versions »

Oligo GEArray® Mouse Toxicology & Drug Resistance Microarray
S Conditions - search.cosmobio.co.jp
... Negative regulation of cell cycle: APC, ATM, BAX, BRCA1, CDKN2A, CDKN2D, MLH1, MSH2,
RB1, TP53. Other cell cycle genes: ABL1, AHR, BCL2, BRCA2, CCNC, CCND1 ...
View as HTML - Web Search

Oligo GEArray® Human Toxicology & Drug Resistance Microarray
S Conditions - search.cosmobio.co.jp
... Negative regulation of cell cycle: APC, ATM, BAX, BRCA1, CDKN2A, CDKN2D, MLH1, MSH2,
RB1, TP53. Other cell cycle genes: ABL1, AHR, BCL2, BRCA2, CCNC, CCND1 ...
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Oligo GEArray® Rat Toxicology & Drug Resistance Microarray
S Conditions - search.cosmobio.co.jp
... Mgmt. Other genes involved in apoptosis: Ahr, Akt1, Bag1, Clu, Dnaja3, E2f1,
Gadd45b, Nfkb1, Tnfrsf1a, Tnfsf10, Tnfsf6, Tp53. Cell ...
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Pancreatic cancer research: challenges, opportunities, and recent developments.
ME Fernandez-Zapico, JA Kaczynski, R Urrutia - Current Opinion in Gastroenterology, 2002 - co-gastroenterology.com
... Abbreviations:AhR aryl hydrocarbon receptor, Arnt aryl hydrocarbon receptor nuclear
translocator ... a homozygous deletion of the tumor suppressor gene p53 (TP53). ...
Web Search - co-gastroenterology.com

Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells … - Full text - MIT Libraries
N Martinez, M Sanchez-Beato, A Carnero, V Moneo, … - Mol Cancer Ther, 2005 - mct.aacrjournals.org
... expression levels of TAp73 and Np73 genes were not related to TP53 status or ... resistant
cells has also revealed a set of genes, including MMP3, AHR, and TIMP3 ...
Web Search - mct.aacrjournals.org - ncbi.nlm.nih.gov

The proteasome in cancer biology and treatment - Full text - MIT Libraries
F Pajonk, WH McBride - Radiat. Res, 2001 - bioone.org
... In addition, mutated TP53 can be stabilized by binding of HSP90, which could be ... ARNT
is able to bind to the aryl hydrocarbon receptor (AHR) and subsequently ...
Cited by 13 - Web Search - strahlenbiologie.bei.t-online.de - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - all 5 versions »

Lung cancer susceptibility
S Mollerup, D Ryberg, V Skaug, A Haugen - Norsk Epidemiologi, 2002 - medisin.ntnu.no
... breast tumor cell lines, it has been demonstrated that the presence of ER may be
important for the induction of CYP1A1 via the AhR (34 ... The TP53 mutation database ...
View as HTML - Web Search

GEArray Q Series Human Cancer Drug Resistance & Metabolism Gene Array: AR-SAHS-019
FG Grouping - eurogentec.com
... BAX, BCL2, BCL2L1 (bcl-x), MVP (LRP), RB1, TOP1, TOP2A, TOP2B, TP53 (p53). ... Transcription
Factors: AHR, AP1S1, ELK1, FOS (c-fos), HIF1A, MAFB, MYC (c-myc), NFKB1 ...
View as HTML - Web Search - eurogentec.be

Molecular Detection of Early Lung Cancer - Full text - MIT Libraries
AF Gazdar, JD Minna - Journal of the National Cancer Institute, 1999 - jncicancerspectrum.oupjournals.org
... found that point mutations in the p53 (also known as TP53) and ras ... or mediastinal
biopsies, and the bronchoalveolar lavage (BAL) technique used by Ahr- endt et ...
Cited by 30 - Web Search - ingentaconnect.com - ingentaconnect.com - ncbi.nlm.nih.gov

Somatic mutations in the p 53 gene and prognosis in breast cancer: a meta-analysis - Full text - MIT Libraries
PDP Pharoah, NE Day, C Caldas - British Journal of Cancer, 1999 - nature.com
... Cancer Res 58: 1451–1455 Gohring UJ, Scharl A, Heckel C, Ahr A and ... Olafsdottir K,
Agnarsson BA, Ogmundsdottir H and Eyfjord JE (1996) TP53 mutation analyses ...
Cited by 47 - Web Search - nature.com - ncbi.nlm.nih.gov

Characteristic Expression Profiles Induced by Genotoxic Carcinogens in Rat Liver - Full text - MIT Libraries
… -Ziegelbauer, B Stuart, B Wahle, W Bomann, HJ Ahr - Toxicological Sciences, 2004 - toxsci.oupjournals.org
... Articles by Ellinger-Ziegelbauer, H. Articles by Ahr, HJ. ... Heidrun Ellinger-Ziegelbauer *
,1 , Barry Stuart , Brad Wahle , Werner Bomann and Hans-Jürgen Ahr * ...
Cited by 7 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - csa.com - all 6 versions »

Expression array technology in the diagnosis and treatment of breast cancer - Full text - MIT Libraries
SS Jeffrey, MJ Fero, AL Borresen-Dale, D Botstein - Mol Interv, 2002 - molinterv.aspetjournals.org
... B group had and only 13% of the Luminal A group contained TP53 mutations. ... Ahr and
colleagues (18,19) have identified a different set of marker genes in fifty ...
Cited by 8 - Web Search - faculty.evansville.edu - dx.doi.org - ncbi.nlm.nih.gov - all 6 versions »

Dysregulation of apoptosis is a major mechanism in the lymph node involvement in colorectal … - Full text - MIT Libraries
E BANDRES, V CATALAN, I SOLA, B HONORATO, E CUBEDO … - ONCOLOGY REPORTS, 2004 - 147.52.72.117
... TK1, TP53, TP53BP2, Drug resistance proteins ABCC2, BCRP, CRA, DPYD, GST-T1, LRP,
MDR1, MRP1, SOD2, TopoIIA, UBL1, UMPK, UMPS, XRCC1 Transcription factors AHR, ...
View as HTML - Web Search - ncbi.nlm.nih.gov

Nature and nurture– lessons from chemical carcinogenesis - Full text - MIT Libraries
A Luch - Nature Reviews Cancer, 2005 - nature.com
... Studies using the AhR-null mice. Drug Metab. Dispos. ... 69. Mimura, J. & Fujii-Kuriyama,
Y. Functional role of AhR in the expression of toxic effects by TCDD. ...
Cited by 2 - Web Search - nature.com - ncbi.nlm.nih.gov

Molekularbiologische Klassifikation von Hochrisiko-Patientinnen beim primaeren Mammakarzinom durch … - Full text - MIT Libraries
A Ahr, U Holtrich, C Solbach, A Scharl, K … - Geburtshilfe und Frauenheilkunde, 2001 - thieme-connect.com
... 1 Ahr A, Holtrich U, Karn T, Solbach C, Göhring UJ, Scharl A, Strebhardt K ... OD, von
Deimling A. Genomic deletions in the BRCA1, BRCA2 and TP53 regions associate ...
Cited by 1 - Web Search

GEArray Q Series Human Breast Cancer and Estrogen Receptor Signaling Gene Array: AR-SAHS-020
FG Grouping - eurogentec.com
... maspin), SERPINE1 (PAI-1), TGFA, THBS1 (thrombospondin-1), TIE (Tie-1), TNFRSF6
(Fas), TNFSF6 (FasL), TOP2A (topoisomerase Iia), TP53, VEGF ... 3. Ahr A, et al. ...
View as HTML - Web Search - eurogentec.be

Genomics in breast cancer—therapeutic implications
PE Loenning, T Soerlie, AL Boerresen-Dale - Nature Clinical Practice Oncology, 2005 - nature.com
... like c-erbB-2 overexpression seem to be associated with a dose-response relationship
to anthracycline sensitivity, 6 and mutations in the TP53 gene that are ...
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Supplementary methods and information
C Klein - nature.com
... EEF1A1 GHPDH ACTB KRT19 TIMP1 CTSB ITGB4 ITGB5 TP53 KRT10 KRT13 ADAM9 Page 9. 9 ... ADSL
HLADQ1B PKUA ADSS HLADRB1 PLA2 AHR HMG2 PLAU AK1 HMGIY PLAUR ANT2 HNRPK PM5 ...
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Overexpression of p 53 Protein in Cutaneous T Cell Lymphoma: Relationship to Large Cell … - Full text - MIT Libraries
G Li, L Chooback, JT Wolfe, AH Rook, CA Felix, SR … - Journal of Investigative Dermatology, 1998 - blackwell-synergy.com
... Fund Award (KES); NIH grants T32 AR 07565 (LC & GL), R01 CA 58841 (AHR), R29 CA ... 18,
Ara, S, Lee, PSY, Hansen, MF, Saya, H. Codon 72 polymorphism of the TP53 gene ...
Cited by 21 - Web Search - jidonline.org - ncbi.nlm.nih.gov

[BOOK] Protein-Protein Interactions: A Molecular Cloning Manual
E Golemis - 2002 - print.google.com
Page 1. Protein—Protein Interactions A Molecular Clon ing Ma nual
iiiiiiiiFiãiiiiiiiiii KZ61-3QL-W8w8 Page 2. Protein—Protein Interactions ...
Cited by 14 - Web Search - Get it from MIT Libraries - Library Search

In Saccharomyces cerevisiae, the RAD10 and RAD1 genes
LHPTMFIN RATS - doi.wiley.com
Page 1. 2000 EMS Abstracts 9 1 OXIDATIVE MUTAGENESIS INDUCED BY NITRIC OXIDE AND
HYDROGEN PEROXIDE IN THE G12 TRANSGENIC CHINESE HAMSTER CELLS. ...
Web Search - doi.wiley.com

Genetische Risikofaktoren des Mammakarzinoms
MW Beckmann, PA Fasching, C Gall, M Bani, C Brumm, … - Der Gynaekologe, 2002 - springerlink.com
... Hierbei spie- len neben dem TP53-Gen, dem ATM- Gen (Ataxia teleangiectatica) und
dem PTEN-Gen (Cowden-Syndrom) vor al- lem das BRCA1- und das BRCA2-Gen (Breast ...
Cited by 2 - Web Search - Get it from MIT Libraries

Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells - Full text - MIT Libraries
M van Erk, E Teuling, Y Staal, S Huybers, P van … - Journal of Carcinogenesis, 2004 - dx.doi.org
... Curcumin downregulated expression of tumor protein p53 (TP53) (Figure 3), a ... Expression
of the aryl hydrocarbon receptor (AHR) was also slightly downregulated ...
Cited by 2 - Web Search - pubmedcentral.nih.gov - carcinogenesis.com - citebase.eprints.org - all 9 versions »

ICTX Congress Special Issue - Full text - MIT Libraries
I LECTURES - Toxicology and Applied Pharmacology, 2004 - adlitip.ankara.edu.tr
... the new CYP2S family, it exhibits many features typical to CYP1 family members,
eg dioxin-inducibility mediated by aryl hydro- carbon receptor (AHR) and aryl ...
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Allelic imbalance in hMLH1 or BRCA2 loci associated with response of cervical and endometrial cancer … - Full text - MIT Libraries
DA ARVANITIS, E ANGELAKIS, EE KOUMANTAKIS, DA … - INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2002 - virology.med.uoc.gr
... D13S290 13q12.1 0.75 241-253 260 C D13S289 13q12.1 0.74 260-276 280 D TP53
17p13.1 0.9 103-135 150 b THRA1 17q11.2-q12 0.81 158-176 150 C ...
Cited by 1 - View as HTML - Web Search - 147.52.72.117 - ncbi.nlm.nih.gov

Bioassay of mannitol and caprolactam and assessment of response to diethylnitrosamine in … - Full text - MIT Libraries
G SchluEter, HG Enzmann, GM Williams - Arch Toxicol, 2001 - springerlink.com
... of DNA adduct for- mation may re¯ect the fact that the TP53 mutation is not ...
26:461±473 Enzmann H, Iatropoulos M, Brunnemann KD, Bomhard E, Ahr HJ, Schlueter ...
Cited by 3 - Web Search - environmental-center.com - environmental-expert.com - ncbi.nlm.nih.gov - all 5 versions »

Molekulare Frauenheilkunde
M Medizin, G Diagnostik - Der Gynaekologe, 2002 - springerlink.com
... ATM-)Erkrankung (11q22 ATM); Familiäres Mamma-/Ovarial- Syndrom (HBOC; 13q12 BRCA2,
17q21 BRCA1); Li-Fraumeni-Syndrom (LFS; 17p13 TP53)] hat die Nachfrage ...
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Analysis of genomic DNA alterations and mRNA expression patterns in a panel of human pancreatic …
S Gysin, P Rickert, K Kastury, M McMahon - GENES, CHROMOSOMES & CANCER, 2005 - doi.wiley.com
... Genomic alterations influencing the expression and/or activity of tumor suppressors
or oncogenes such as KRAS2, CDKN2A, TP53, and DPC4 have been directly ...
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Journal of Carcinogenesis - Full text - MIT Libraries
MJ van Erk, E Teuling, YCM Staal, S Huybers, PJ … - Journal of Carcinogenesis, 2004 - bmc.ub.uni-potsdam.de
Page 1. ...
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A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of …
D Genetica, SU e Ambiente, C Articles - jpharmacogenetics.com
... Evaluating the arrayed primer extension resequencing assay of TP53 tumor suppressor
gene ... Ma Q. Induction of CYP1A1 The AhR/DRE paradigm: transcription, receptor ...
Web Search

Promise of new technologies in understanding pre-invasive breast lesions - Full text - MIT Libraries
SS Jeffrey, JR Pollack - Breast Cancer Res, 2003 - stanford.edu
... the retained, non-random genomic DNA gains and losses drive aberrant expression
of oncogenes (eg ERBB2) and tumor-suppressor genes (eg TP53), con- tributing to ...
Cited by 2 - View as HTML - Web Search - citebase.eprints.org - pubmedcentral.nih.gov - breast-cancer-research.com - all 9 versions »

Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a … - Full text - MIT Libraries
A Lamy, R Sesboue, J Bourguignon, B Dautreaux, J … - Int J Cancer, 2002 - doi.wiley.com
... In contrast to TP53 mutations, 40 the role of tobacco smoke exposure in CDKN2A ... 8.
Yuan J, Knorr J, Altmannsberger M, Goeckenjan G, Ahr A, Scharl A, Strebhardt K ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov

Risikoberechnungsverfahren fuer die Entstehung eines Mammakarzinoms und das Vorliegen einer …
D der Medizin - deposit.ddb.de
... DNA-Schäden am Erbgut genetische Prädisposition (BRCA1/2; TP53; RB; AT) ... TP53, Ataxia
Telangiectasia-Gen (AT), PTEN, HRAS1 und Mismatchrepair-Gene wie ...
Web Search

CYP1A1 and GSTM1 genotypes affect benzo [a] pyrene DNA adducts in smokers' lung: comparison with … - Full text - MIT Libraries
K Alexandrov, I Cascorbi, M Rojas, G Bouvier, E … - Carcinogenesis, 2002 - carcin.oupjournals.org
... of CYP1A1 in human lung is not ascribed to polymorphisms in the AHR, ARHT, or ... analysis
of PAH-DNA adducts in human lung and relationship to TP53 mutations. ...
Cited by 14 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov - csa.com - all 8 versions »

Immunohistochemical evaluation of cathepsin D in normal, hyperplastic and malignant endometrium: … - Full text - MIT Libraries
E Ioachim, E Kitsiou, K Charalabopoulos, A … - International Journal of Gynecological Cancer, 2003 - ingentaconnect.com
... Mod Pathol 1994;7:469—74. 21 FIGO stages-1988 revisions,. Gynecol Oncol
1989;35:125—7. 22 Gohring UJ, Scharl A, Thelen U, Ahr A, Crombach G, Titius BR. ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov

TWO STEP MECHANISM FOR FORMATION OF COMPLEX 9; 22 CHROMOSOME TRANSLOCATION IN CHRONIC MYELOCYTIC …
AII NEIAeIIE, ANI AEAÐEAeECAOeEE - Experimental Oncology, 2001 - exp-oncology.com.ua
... and 9p12 region was precisely analyzed using seven cosmid probes mapped on 17p13
(D17S34, cCl17-624, cCl17-453, D17S379, cCl17-636, cCl17-732, TP53) and two ...
Cited by 1 - Web Search - morion.kiev.ua

CDKN 2 A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine … - Full text - MIT Libraries
AL Cook, PM Pollock, J Welch, MD Walsh, RV Bowman, … - International Journal of Cancer, 2001 - doi.wiley.com
... expression in neuroendocrine tumors of the lung. Cancer 2000;88: 550–6. 16. Yuan
J, Knorr J, Altmannsberger M, Goeckenjan G, Ahr A, Scharl A, et al. ...
Cited by 8 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov

Characterisation of biomolecular profiles in primary high-grade prostate cancer treated by radical … - Full text - MIT Libraries
H Augustin, PG Hammerer, M Graefen, J Palisaar, F … - Journal of Cancer Research and Clinical Oncology, 2003 - springerlink.com
... of p53 is an abnormal finding which may indicate a mutation in the TP53 gene. ... J Urol
167:528–534 Ismail AHR, Landry F, Aprikian AG, Chevalier S (2002) Andro ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

[BOOK] Lung Cancer: Volume 1: Molecular Pathology Methods and Reviews
RH Miller, B Driscoll - 2002 - print.google.com
Page 1. Lung Cancer Volume 1 Page 2. METHODSINMOLECULARMED ICINE John M. Walker,
Series Editor 79. Drugs of Abuse: Neurological Reviews and 62. ...
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Value of epidermal growth factor receptor, HER2, p53, and steroid receptors in predicting the … - Full text - MIT Libraries
AS Knoop, SM Bentzen, MM Nielsen, BB Rasmussen, C … - J Clin Oncol, 2001 - jco.org
... Br J Cancer 69: 26-31, 1994[Medline]; Göhring UJ, Scharl A, Ahr A: Value ... Andersen
TI, Holm R, Nesland JM, et al: Prognostic significance of TP53 alterations in ...
Cited by 21 - Web Search - jco.org - ncbi.nlm.nih.gov

Application of DNA microarray technology in determining breast cancer prognosis and therapeutic …
DJ Brennan, S LO’Brien, A Fagan, AC Culhane, DG … - Expert Opin. Biol. Ther, 2005 - ashley-pub.com
... Ahr [35] 21 cDNA (45,000) HC + SOM n/a n/a n/a n/a n/a n/a n/a ... TP53 tumour suppressor
gene, whereas only 13% of luminal A tumours harboured TP53 mutations. ...
Web Search - ashley-pub.com

Research Article Carboxypeptidase E and thrombospondin-1 are differently expressed in subcutaneous …
JM Ramis, NLW Franssen-van Hal, E Kramer, I Llado, … - springerlink.com
Page 1. Research Article Carboxypeptidase E and thrombospondin-1 are differently
expressed in subcutaneous and visceral fat of obese subjects ...
Web Search

Distinct and Complementary Information Provided by Use of Tissue and DNA Microarrays in the Study of … - Full text - MIT Libraries
C Ginestier, E Charafe-Jauffret, F Bertucci, F … - development - ajp.amjpathol.org
... In addition, other molecules, such as CDH1, Ki67, TP53, progesterone receptor, TACC1,
20 and TACC2, were re- tained because of a known or suspected role in ...
Cited by 24 - Web Search - ingentaconnect.com - utoronto.ca - ncbi.nlm.nih.gov - all 6 versions »

Extrahepatic cytochrome P450s–relation to cancer susceptibility
TR Rudqvist - diss.kib.ki.se
... AhR aryl hydrocarbon receptor B(a)P benzo(a)pyrene BMI body mass index CI confidence
interval COC combined oral contraceptives COMT catechol-O ...
Web Search

Bioavailability and Risk Assessment of Orally Ingested Polycyclic Aromatic Hydrocarbons
A Ramesh, S Walker, D Hood, M Guillen, K Schneider … - International Journal of Toxicology, 2004 - dx.doi.org
... 1997). Ah receptor (Ahr) signaling plays an important role in regulation and induction
of several drug metabolizing en- zymes such as CYP1A1, CYP1A2, CYP1B1 ...
Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

Cancer DE Mama: Marcadores Tumorais (Revisao DE Literatura)
ALA Eisenberg, S Koifman - Revista Brasileira de Cancerologia, 2001 - inca.gov.br
Page 1. 377 RESUMO A identificação de marcadores que possam predizer o
comportamento dos tumores é especialmente importante em ...
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Pattern recognition tumor targetting
A Glazier - Transactions of the integrated biomedical informatics and …, 2004 - tibetsjournal.org
Page 1. Transactions of the Integrated Biomedical Informatics & Enabling
Technologies Symposium Journal 2004, 1; 61-78. Windber ...
Cited by 2 - View as HTML - Web Search

BRCA 1 gene in breast cancer - Full text - MIT Libraries
EM Rosen, S Fan, RG Pestell, ID Goldberg - Journal of Cellular Physiology, 2003 - doi.wiley.com
Page 1. JOURNAL OF CELLULAR PHYSIOLOGY 196:19–41 (2003) BRCA1 Gene in Breast
Cancer ELIOT M. ROSEN, 1,2,3,5 * SAIJUN FAN, 1,2 RICHARD ...
Cited by 26 - Web Search - biology.mcgill.ca - ww2.mcgill.ca - ncbi.nlm.nih.gov

The absence of Msh2 alters abelson virus pre-B-cell transformation by influencing p53 mutation - Full text - MIT Libraries
J Jenab-Wolcott, D Rodriguez-Correa, AH Reitmair, … - Mol Cell Biol, 2000 - mcb.asm.org
... GM 08448, DR-C. was supported by grant HL07785, and AHR was supported by a ... Mutation
of Tp53 contributes to the malignant phenotype of Abelson virus-transformed ...
Cited by 3 - Web Search - pubmedcentral.nih.gov - mcb.asm.org - ncbi.nlm.nih.gov