MUTATION ANALYSIS OF EP300 IN COLON, BREAST AND OVARIAN CARCINOMAS - Full text - MIT Libraries
IG Campbell - Int. J. Cancer, 2002 - doi.wiley.com
... 20,21 Other key roles for EP300 are in the apoptotic response to DNA damage
as EP300 is intrinsic in the acetylation of TP53. 22,23 ...
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No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative … - Full text - MIT Libraries
BC Res - Breast Cancer Res, 2004 - dx.doi.org
... BRCA2, ATM, TP53, CHK2 and PTEN account for many, but not all, multiple-case breast
and ovarian cancer families. The histone acetyltransferase gene EP300 may ...
Web Search - breast-cancer-research.com - breast-cancer-research.com - biomedcentral.com - all 6 versions »

Analysis of genetic stability at the EP 300 and CREBBP loci in a panel of cancer cell lines
GW Tillinghast, J Partee, P Albert, JM Kelley, KH … - Genes Chromosomes and Cancer, 2003 - doi.wiley.com
... There was no increased tendency for cell lines with wild-type TP53 as compared to
mutant TP53 to have LOH for either the EP300 or CREBBP genetic loci. ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

MOLECULAR PATHOGENESIS OF PANCREATIC CANCER - Full text - MIT Libraries
DE Hansel, SE Kern, RH Hruban - Annual Review of Genomics and Human Genetics, 2003 - fluid.annualreviews.org
... include CDKN2A/p16/MTS1 (95%), TP53 (50–75%), and MADH4/SMAD4/DPC4 (55%) (56). Less
frequently affected genes include BRCA2, MKK4, EP300, STK11, ALK4/ACVR1B ...
Cited by 10 - Web Search - fluid.annualreviews.org - nutr.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

GEArray Q series Human p53 Signaling Pathway Gene Array: AR-SAHS-027
FG Grouping - eurogentec.com
... p53 family: TP53, TP63, TP73 p53 upstream signal/p53 modifiers p53 expression and
stability: BZRP (pBR), CREBBP (CBP), D5S346 (DP1), E2F1 (E2F), EP300 (p300 ...
View as HTML - Web Search - eurogentec.be

GEArray Q series Human p53 Signaling Pathway Gene Array Cat. No.* Kit Size HS-027-2/HS-027N-2 2 …
FG Grouping - tebu-bio.com
... p53 family: TP53, TP63, TP73 p53 upstream signal/p53 modifiers: p53 expression and
stability: BZRP (pBR), CREBBP (CBP), D5S346 (DP1), E2F1 (E2F), EP300 (p300 ...
View as HTML - Web Search

GEArray Q series Human p53 Signaling Pathway Gene Array
FG Grouping - superarray.com
... p53 family: TP53, TP63, TP73 p53 upstream signal/p53 modifiers p53 expression and
stability: BZRP (pBR), CREBBP (CBP), D5S346 (DP1), E2F1 (E2F), EP300 (p300 ...
View as HTML - Web Search - superarray.com - cosmobio.co.jp - cosmobio.co.jp - all 5 versions »

No germline mutations in the histone acetyltransferase gene EP 300 in BRCA 1 and BRCA 2 negative … - Full text - MIT Libraries
I Campbell, D Choong, G Chenevix-Trench - Breast Cancer Res, 2004 - pubmedcentral.nih.gov
... BRCA2, ATM, TP53, CHK2 and PTEN account for many, but not all, multiple-case breast
and ovarian cancer families. The histone acetyltransferase gene EP300 may ...
Web Search - bmc.ub.uni-potsdam.de - citebase.eprints.org - ncbi.nlm.nih.gov

CHEKs and balances: accounting for breast cancer - Full text - MIT Libraries
LC Brody - Nature Genetics, 2002 - nature.com
... No mutations were found in EP300, a gene encoding a histone ... ATM, ataxia-telangiectasia;
BRCA1, inherited breast and ovarian cancer syndrome; TP53, Li-Fraumeni ...
Cited by 3 - Web Search - nature.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov

High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian …
M Benetkiewicz, Y Wang, M Schaner, P Wang, KK … - Genes Chromosomes and Cancer, 2005 - doi.wiley.com
... The EP300 gene is considered a tumor suppressor that encodes the interacting
protein between BRCA1 and TP53 (Pao et al., 2000). ...
Cited by 3 - Web Search - puffer.genpat.uu.se - ncbi.nlm.nih.gov - Get it from MIT Libraries

GEArray S Series Human Immunology Signaling Pathways Gene Array: AR-SAHS-605
FG Grouping, A Molecules, I ICAM, CS Molecules, C … - eurogentec.com
... CEBPB, CREB1, CREBBP, EGFR, EGR1, EGR2, EGR3, ELK1, ELK3, ELK4, EP300, ETS1, ETS2 ...
MYF5, NFKB2, NFKBIB, NFKBIE, NR4A2, PCNA, RAF1, RELA, RPS6KA5, SP1, SP3, TP53. ...
View as HTML - Web Search - eurogentec.be

Prognostic value of cytogenetic findings in adults with acute myeloid leukemia
K Mrozek, K Heinonen, CD Bloomfield - Int J Hematol, 2000 - static.cjp.com
... The only exception is the TP53 gene found to be inactivated in many patients with
AML ... t(8;16)(p11;p13)† MOZ-CBP t(8;22)(p11;q13) ,¶ MOZ-EP300 Involving the ...
Cited by 19 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Allelic losses of loci at 3p25. 1, 8p22, 13q12, 17p13. 3, and 22q13 correlate with postoperative … - Full text - MIT Libraries
A Hirano, M Emi, M Tsuneizumi, Y Utada, M … - Clin Cancer Res, 2001 - clincancerres.aacrjournals.org
... or the MYCC proto-oncogene (20, 21, 22) , mutations or overexpression of TP53 (23,
24 ... respect to the newly identified site of LOH at 22q13, the EP300 gene is a ...
Cited by 12 - Web Search - clincancerres.aacrjournals.org - ncbi.nlm.nih.gov

Emerging issues in genotoxicology
BJ Barclay - currentdrugdiscovery.com
... hydrolase organelles EP300 Histone acetyltransferase Regulation of transcription
Colorectal, breast ... TP53 P53 protein Regulation of G 2 /M cell cycle Li-Fraumeni ...
View as HTML - Web Search - inpharm.com

The p 53 pathway in breast cancer - Full text - MIT Libraries
M Gasco, S Shami, T Crook - Breast Cancer Res, 2002 - dx.doi.org
... Ponder BAJ, Kouzarides T, Caldas C: Mutations truncating the EP300 acetylase in ... LL,
Overgaard J: Heterogeneity in the clinical phenotype of TP53 mutations in ...
Cited by 12 - Web Search - pubmedcentral.nih.gov - breast-cancer-research.com - citebase.eprints.org - all 10 versions »

Genetic and cytogenetic analyses of breast cancer yield different perspectives of a complex disease - Full text - MIT Libraries
P O’Connell - Breast Cancer Res. Treat, 2003 - springerlink.com
... 50] TP53 a Tumor protein 53 TSG, DNA repair 17p13.2 Both [20] ... 22] EP300 E1A
binding protein TSG, chromatin remodeling 22q13 Both [60] ...
Cited by 4 - Web Search - kluweronline.com - ingentaconnect.com - ncbi.nlm.nih.gov

Gene discovery in bladder cancer progression using cDNA microarrays - Full text - MIT Libraries
M Sanchez-Carbayo, ND Socci, JJ Lozano, W Li, E … - Am J Pathol, 2003 - ajp.amjpathol.org
... in invasive tumors (Fig- ure 3, A and B). Because both TP53 and RB ... 3A (STX3A) AA488526
Nucleolar phosphoprotein p130 N94428 E1A binding protein p300 (EP300) ...
Cited by 21 - Web Search - nslij-genetics.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 7 versions »

The role of emerging genomics and proteomics technologies in cancer drug target discovery.
P Onyango - Current Cancer Drug Targets, 2004 - ingentaconnect.com
... EP300 E1A-binding protein (p300) gene Colorectal; breast and pancreatic cancers ... TP53
Tumor suppressor p53 gene Li-Fraumeni syndrome and a wide variety of tumors ...
Cited by 2 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Research Article
M Nakamura, E Ishida, K Shimada, M Kishi, H Nakase … - nature.com
... al, 14 however, did not find evidence of somatic mutations in EP300, and DJ1042K10 ...
is frequently associated with G:C A:T mutations of the TP53 tumor suppressor ...
Cached - Web Search - nature.com

Frequent LOH on 22 q 12. 3 and TIMP-3 inactivation occur in the progression to secondary … - Full text - MIT Libraries
M Nakamura, E Ishida, K Shimada, M Kishi, H Nakase … - Laboratory Investigation, 2005 - nature.com
Page 1. Frequent LOH on 22q12.3 and TIMP-3 inactivation occur in the
progression to secondary glioblastomas Mitsutoshi Nakamura 1 ...
View as HTML - Web Search - nature.com - ncbi.nlm.nih.gov

Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell … - Full text - MIT Libraries
M Grigorova, JM Staines, H Ozdag, C Caldas, PAW … - Cytogenetic and Genome Research, 2004 - content.karger.com
... Or, like TP53 mutation, they may be per- missive, but not sufficient, for ... JD, Ponder
BA, Kouzarides T, Cal- das C: Mutations truncating the EP300 acetylase in ...
Web Search - dx.doi.org - karger.com - ncbi.nlm.nih.gov - all 5 versions »

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease … - Full text - MIT Libraries
A Barbouti, M Hoglund, B Johansson, C Lassen, PG … - Cancer Res, 2003 - cancerres.aacrjournals.org
... mostly focused on well-known tumor suppressor genes (eg, TP53, CDKN2A, and RB1 ...
transformation and also recruits the transcriptional coactivators CREBBP/EP300 ( ...
Cited by 8 - Web Search - cancerres.aacrjournals.org - ncbi.nlm.nih.gov - lu-research.lub.lu.se - all 5 versions »

Candidate nsSNPs That Can Affect the Functions and Interactions of Cell Cycle Proteins - Full text - MIT Libraries
S Savas, MF Ahmad, M Shariff, DY Kim, H Ozcelik - risk - doi.wiley.com
... cancer. 1,2 In addition, germ-line mutations in several cell cycle control
genes such as RB1, 3 BRCA1 and BRCA2, 4 TP53, 5 NF2, 6 and ...
Web Search - ijmm.org - ncbi.nlm.nih.gov

Genetic and epigenetic alterations of the candidate tumor-suppressor geneMYO 18 B, on chromosome arm …
T Nakano, M Tani, M Nishioka, T Kohno, A Otsuka, S … - Genes Chromosomes and Cancer, 2005 - doi.wiley.com
... in colorectal cancer pro- gression, such as APC, on 5q, and TP53, on 17p ... known TSGs
that are inactivated in several types of human cancers: NF2, EP300, and SNF5 ...
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Identification of Novel Candidate Oncogenes and Tumor Suppressors in Malignant Pleural Mesothelioma … - Full text - MIT Libraries
GJ Gordon, GN Rockwell, RV Jensen, JG Rheinwald, … - American Journal of Pathology, 2005 - ajp.amjpathol.org
Page 1. Tumorigenesis and Neoplastic Progression Identification of Novel Candidate
Oncogenes and Tumor Suppressors in Malignant Pleural ...
Web Search - ajp.amjpathol.org - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions »

Gene Expression Profiles Reveal that DCN, DIO 1, and DIO 2 Are Underexpressed in Benign and …
LAT Arnaldi, RC Borra, RMB Maciel, JM Cerutti - Thyroid, 2005 - dx.doi.org
... such as rearrangements in RET, NTRK1, and PAX8-PPAR ; activating point mutations
in BRAF, RAS, GSP; inactivating point mutations in TP53, RB1; overexpres- sion ...
Web Search - liebertonline.com - liebertonline.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

[BOOK] Molecular biology of cancer
F Macdonald, CHJ Ford, AG Casson - 2004 - print.google.com
... 40 3.4 TPS3 (p53) 41 3.4.1 The TPS3 gene and its protein productp53 41 3.4.2 Activation
of TP53 42 3.4.3 Activatedp53 responses — cell cycle inhibition 44 ...
Cited by 10 - Web Search - Get it from MIT Libraries - Library Search

Genes, chromatin, and breast cancer: an epigenetic tale
LM Mielnicki, HL Asch, BB Asch - J Mammary Gland Biol Neoplasia, 2001 - kluweronline.com
Page 1. Journal of Mammary Gland Biology and Neoplasia, Vol. 6, No. 2, 2001
Genes, Chromatin, and Breast Cancer: An Epigenetic Tale ...
Cited by 10 - Web Search - springerlink.com - ingentaconnect.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

1. SYNERGISTIC ANTIGLIOMA ACTIVITY OF INTERLEUKIN-12 AND INTERLEUKIN-18
MOFARIN HUMAN, MGRR CELL, IN VIVO - ingentaconnect.com
Page 1. 374 Neuro-Oncology n OCTOBER 2003 1. SYNERGISTIC ANTIGLIOMA ACTIVITY
OF INTERLEUKIN-12 AND INTERLEUKIN-18 Koji Adachi; Nippon ...
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Bibliography Current World Literature
E Tumors - Current Opinion in Oncology, 2005 - co-oncology.com
January 2005, 17:1 > Bibliography Current World Literature. ...
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Epigenetic and Chromatin Modifiers As Targeted Therapy of Hematologic Malignancies - Full text - MIT Libraries
KN Bhalla - J Clin Oncol, 2005 - jco.org
Search for: Limit by: All Topics ...
Cited by 2 - Web Search - dx.doi.org - jco.org - ncbi.nlm.nih.gov

Epigenetics and cancer - Full text - MIT Libraries
AH Lund, M van Lohuizen - Genes & Development, 2004 - genesdev.org
Institution: Google Indexer Sign In as Individual. GENES &
DEVELOPMENT 18:2315-2335, 2004 ISSN 0890-9369/ $5.00 ...
Cited by 11 - Web Search - dx.doi.org - genesdev.org - ncbi.nlm.nih.gov