A comparative analysis of relative occurrence of transcription factor binding sites in vertebrate … - Full text - MIT Libraries
M Stepanova, T Tiazhelova, M Skoblov, A Baranova - Bioinformatics, 2005 - bioinformatics.oxfordjournals.org
... Five TFs, namely TP53, NRSF, EVI1, SP1 and GC box element were characterized by
real occurrences prevailing on F-values in all five vertebrate genomes analyzed ...
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Cytogenetic and Molecular Genetic Evolution of Chronic Myeloid Leukemia
A Haematologica - Acta Haematologica, 2002 - dx.doi.org
... of the BCR/ABL transcript, upregulation of the EVI1 gene, increased telomerase activity,
and mutations of the tumor suppressor genes RB1, TP53, and CDKN2A. ...
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A Novel Cryptic Translocation t (12; 17)(p13; p12–p13) in a Secondary Acute Myeloid Leukemia …
E MN - GENES, CHROMOSOMES & CANCER, 2003 - doi.wiley.com
... the breakpoints could be localized in intron 1 of ETV6 and centromeric to TP53. ... proteins
as occurring in the translo- cations leading to ETV6-MDS/EVI1 and ETV6 ...
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Copy number changes of target genes in chromosome 3q25. 3-qter of esophageal squamous cell carcinoma …
WHH Wu, LS Wang, MH Huang, BS Huang, CP Hu, PM … - wjgnet.com
... to telomere): SSR3: 4.19 (±0.69); CCNL1: 5.24 (±0.67); SMC4L1: 2.01 (±0.16); EVI1:
2.02 (±0.12 ... TP63 gene, one of TP53 gene family, is a well-known oncogene ...
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Diagnostic value of fluorescence in situ hybridization for the detection of genomic aberrations in … - Full text - MIT Libraries
S Froehling, S Kayser, C Mayer, S Miller, C … - Haematologica, 2005 - haematologica.org
... 3q 858_c_9/14EE12 3q26 EVI1, D3S1212 CEPH/ICI +4q F06184 4q22 RZPD ... 17p–
K0189 17p13 TP53 RZPD 20q– 808_c_5 20q12 D20S99 CEPH ...
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A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease … - Full text - MIT Libraries
A Barbouti, M Hoglund, B Johansson, C Lassen, PG … - Cancer Res, 2003 - cancerres.aacrjournals.org
... studies have mostly focused on well-known tumor suppressor genes (eg, TP53, CDKN2A,
and RB1 ... translocations/fusion genes, eg, t(3;21)(q26;q22)/RUNX1-EVI1, t(7;11 ...
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Pathogenese und Biologie der Leukaemien - Full text - MIT Libraries
M Feuring-Buske, W Hiddemann, C Buske - Der Internist, 2002 - springerlink.com
... dem AML1-MDS1, AML1-EVI1 oder dem kombinierten AML1-MDS1/EVI1-Fusionsgen (Tabelle1 ...
wie zBRB1, pCDKN2 (p16, p15).Alterationen von TP53 (Deletionen, Rearrangements ...
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Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with …
H Van Limbergen, B Poppe, L Michaux, C Herens, J … - Genes Chromosomes and Cancer, 2002 - doi.wiley.com
... Gene-specific probes used were: LSI p53 (encom- passing TP53), LSI MLL dual-color ...
by Dr. Peter Marynen, Leuven, Belgium) (Peeters et al., 1997), EVI1 BAC clones ...
Cited by 21 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia - Full text - MIT Libraries
J Pedersen-Bjergaard, MK Andersen, DH Christiansen … - Blood, 2002 - bloodjournal.org
... Thus, the AML1-MDS1-EVI1 fusion gene, primarily observed in the t(3 ... Distinct genetic
involvement of the TP53 gene in therapy-related leukemia and myelodysplasia ...
Cited by 35 - Web Search - bloodjournal.org - dx.doi.org - ncbi.nlm.nih.gov

Analysis of the interaction of TIP60β and PIN1 with the ets family transcription factor ETV6
CD Zhang - edoc.ub.uni-muenchen.de
... protein tyrosine kinases, such as ARG, NTRK3/TRKC, PDGFRβ, JAK2, ABL, SYK, and
FGFR3, to transcription factors, such as AML1/RUNX1, EVI1, ...
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Cytogenetic and Molecular Genetic Evolution of Chronic Myeloid Leukemia
A Haematologica - Acta Haematologica, 2002 - content.karger.com
... of the BCR/ABL transcript, upregulation of the EVI1 gene, increased telomerase activity,
and mutations of the tumor suppressor genes RB1, TP53, and CDKN2A. ...
Web Search - dx.doi.org - content.karger.com - karger.com

Cytogenetic and Molecular Genetic Evolution of Philadelphia-Chromosome-Positive Chronic Myeloid …
BJTFF Mitelman - content.karger.com
... of the BCR/ABL transcript, up-regula- tion of the EVI1 gene, increased telomerase
activity, and muta- tions of the tumour suppressor genes RB1, TP53, and CDKN2A ...
Web Search - content.karger.com

Search for unknown tumor-antagonizing genes
S Imreh, G Klein, ER Zabarovsky - Genes Chromosomes and Cancer, 2003 - doi.wiley.com
... oncogenesis in a positive fashion. They include FIM3, EVI1, BCL6, ETS1, ERM,
and the RNA subunit of telomerase (hTR). It is noteworthy in ...
Cited by 12 - Web Search - mtc.ki.se - 130.237.124.206 - ncbi.nlm.nih.gov - all 8 versions » - Get it from MIT Libraries

G ENETIC P ROFILE OF A CUTE M YELOID L EUKEMIA - Full text - MIT Libraries
C Mecucci, R Rosati, R La Starza - Reviews in Clinical & Experimental Hematology, 2002 - blackwell-synergy.com
... I gene is involved at 3q21 as in the inv(3). Both EVI1 and MEL1 have a ... such as complete
loss or interstitial deletion of chromosome 5q, and mutations of TP53. ...
Cited by 4 - Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Cytogenetic and Molecular Genetic Evolution of Chronic Myeloid Leukemia
BJTFF Mitelman - Acta Haematol, 2002 - content.karger.com
... of the BCR/ABL transcript, upregulation of the EVI1 gene, increased telomerase activity,
and muta- tions of the tumor suppressor genes RB1, TP53, and CDKN2A. ...
Web Search - content.karger.com - cmlsupport.com

Acute myelogenous leukemia associated with extreme symptomatic thrombocytosis and chromosome 3 q …
VT Chang, H Aviv, LM Howard, F Padberg - American Journal of Hematology, 2003 - doi.wiley.com
... (ii) Digoxigenin-labeled DNA probe TP53, which hybridizes to the ... A gene ho- mologous
to the MDS/EVI1 gene on chromosome 1 is thought to be activated in this ...
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Prognostic value of cytogenetic findings in adults with acute myeloid leukemia
K Mrozek, K Heinonen, CD Bloomfield - Int J Hematol, 2000 - static.cjp.com
... The only exception is the TP53 gene found to be inactivated in many patients with
AML (and ... Affecting the EVI1 gene at 3q26 inv(3)(q21q26)† EVI1 t(3;3)(q21;q26 ...
Cited by 19 - View as HTML - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Mechanisms of BCR–ABL in the pathogenesis of chronic myelogenous leukaemia - Full text - MIT Libraries
R Ren - Nature Reviews Cancer, 2005 - nature.com
... EVI1 was first identified as a gene whose expression was activated by retroviral ...
isolated from patients with blast-phase CML include mutations in TP53, RB, and ...
Cited by 2 - Web Search - nature.com - ncbi.nlm.nih.gov

Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced …
A Barbouti, B Johansson, M Hoeglund, N Mauritzson, … - Genes Chromosomes and Cancer, 2002 - doi.wiley.com
... mainly focused on alterations of well-known tumor-suppressor genes (eg, TP53, CDKN2A,
and ... acute myeloid leukemias (AMLs) (eg, t(3;21)(q26;q22)/CBFA2-EVI1, t(7 ...
Cited by 6 - Web Search - lu-research.lub.lu.se - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Myelodysplastic Syndrome
H Sill - Am J Cancer, 2002 - ingentaconnect.com
... Structural changes on chromosome 3 typically target the EVI1 gene located
on 3q26. [27] Deregulated expression of the EVI1 gene, a ...
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Daniel den Hoed Cancer News
EMCO Magazine - oncologie.nl
Page 1. Daniel den Hoed Cancer News Highlights in Basic and Translational Cancer
Research International Oncology Congress September 17, 2004 ...
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Genetic differences detected by comparative genomic hybridization in head and neck squamous cell …
Q Huang, GP Yu, SA McCormick, J Mo, B Datta, M … - Genes Chromosomes and Cancer, 2002 - doi.wiley.com
... ECT2, EVI1, RAB7, and THPO. How- ever, none of the above-mentioned genes has been
described to be involved in tumorigenesis of HNSCC. The AIS gene, a TP53 ...
Cited by 23 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Cytogenetics and molecular pathology in cancer diagnostics
S Knuutila - Annals of Medicine, 2004 - dx.doi.org
... inv(3)(q21q26)/ ROPN1;EVI1 AMLFrequent presence of thrombocytosis Resistant to
chemotherapy ... Neuroblastoma Poor prognosis (del(17p13)/TP53) CLL Poor prognosis ...
Cited by 1 - Web Search - taylorandfrancis.metapress.com - ingentaconnect.com - ncbi.nlm.nih.gov - all 5 versions » - Get it from MIT Libraries

AML1 interconnected pathways of leukemogenesis
J Michaud, HS Scott, R Escher - Cancer Invest, 2003 - taylorandfrancis.metapress.com
Page 1. MOLECULAR BIOLOGY AND GENETICS AML1 Interconnected Pathways of
Leukemogenesis Joëlle Michaud, Hamish S. Scott, * and Robert Escher ...
Cited by 5 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Bibliography Current World Literature
MR Baer, LA Pixley, LA Ford… - Current Opinion in Oncology, 2002 - co-oncology.com
... gene, MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and ... S, Appelbaum
FR, Slovak ML, Willman CL, Radich JP: FLT3, RAS, and TP53 mutations in ...
Web Search - co-rheumatology.com - co-gastroenterology.com - co-endocrinology.com - all 9 versions »

6 RECURRING CHROMOSOME REARRANGEMENTS IN HUMAN CANCER
OI Olopade, OM Sobulo, JD Rowley - cancer.org
... crisis. The genes cloned at this translocation breakpoint have been AML1,
on band 21q22 fused to EVI1, EAP, or MDS1 on band 3q26. ...
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Epigenetics and cancer - Full text - MIT Libraries
AH Lund, M van Lohuizen - Genes & Development, 2004 - genesdev.org
... 2004 ). MDS-EVI1 was originally annotated as two independent genes. ... EVI1 acts
dominantly over its presumed antagonist MDS-EVI1 (Soderholm et al. ...
Cited by 11 - Web Search - dx.doi.org - genesdev.org - ncbi.nlm.nih.gov

Myeloid- and lymphoid-specific breakpoint cluster regions in chromosome band 13 q 14 in acute …
LJA Coignet, CSP Lima, T Min, B Streubel, J … - Genes Chromosomes and Cancer, 1999 - doi.wiley.com
... Examples of tumor suppressor genes in hematologic malignan- cies include TP53 g
at 17p13.1 (Hollstein ... Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13 ...
Cited by 13 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

De la cytogenetique a la cytogenomique des tumeurs: le point en 2004
A Bernheim, JL Huret, M Guillaud-Bataille, O … - Bull Cancer, 2004 - john-libbey-eurotext.fr
... LAM, myélodysplasies t(3;3)(q21;q26) RPN1-EVI1 ou inv(3)(q21;q26) ou ins(3;3)(q26;
q21q26) t(3;5)(q25 ... Côlon del(17p), TP53 -18 DCC ouDPC4/SMAD4 del(5q21)* APC ...
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Myelodysplastic syndromes: recent advances - Full text - MIT Libraries
EP Alessandrino, S Amadori, M Cazzola, F Locatelli … - Haematologica, 2001 - haematologica.it
Page 1. haematologica vol. 86(11):november 2001 Correspondence: Prof. Sante
Tura, MD, Istituto di Ematologia e Oncolo- gia Medica ...
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Der Einsatz der vergleichenden genomischen Hybridisierung, CGH, im Vergleich zur klassischen …
IN Hahntow - vts.uni-ulm.de
... ETS v-ets avian erythroblastosis virus oncogene homolog EVI1 ectropic viral
integration site 1 ... oncogene homolog TP53 tumor protein p53 ...
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Brief Data Reports
W Pretsch, J Favor, LL Peters, SL Ciciotte, L Lin, … - springerlink.com
Page 1. Brief Data Reports A precise localization of a mouse gene encoding increased
phosphoglycerate mutase activity (Pgam1e1) on Chromosome 19 ...
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Multicolor karyotyping in acute myeloid leukemia
J Tchinda, S Volpert, N McNeil, T NEUMANN, I … - Leuk Lymphoma, 2003 - taylorandfrancis.metapress.com
... aberrations involving new translocation partners of RUNX1, at(3;21)(p13 or
p?25;q22) and at(7;21)(p22;q22), as well as one translocation involving EVI1, t( ...
Cited by 1 - Web Search - ncbi.nlm.nih.gov - ncbi.nlm.nih.gov - Get it from MIT Libraries

Multicolor Karyotyping in Acute Myeloid Leukemia
J TCHINDA, S VOLPERT, N McNEIL, T NEUMANN, I … - Leukemia & Lymphoma, 2003 - dx.doi.org
... aberrations involving new translocation partners of RUNX1, at(3;21)(p13 or
p?25;q22) and at(7;21)(p22;q22), as well as one translocation involving EVI1, t( ...
Web Search

Leukemias related to treatment with DNA topoisomerase II inhibitors
CA Felix - Medical and Pediatric Oncology, 2001 - doi.wiley.com
... t(3;21)(q26;q22) translocations are variant transloca- tions that fuse AML1 and
the EVI1, EAP, MDS1 gene cluster in treatment-related AML and treatment-related ...
Cited by 34 - Web Search - doi.wiley.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

Paroxysmal nocturnal haemoglobinuria clones in patients with myelodysplastic syndromes - Full text - MIT Libraries
M Iwanaga, K Furukawa, T Amenomori, H Mori, H … - British Journal of Haematology, 1998 - ingentaconnect.com
Page 1. Paroxysmal nocturnal haemoglobinuria clones in patients with
myelodysplastic syndromes M ASAKO I WANAGA , 1 K OICHI F URUKAWA ...
Cited by 24 - Web Search - ncbi.nlm.nih.gov

POSTER SESSION I
CD Baldus, SM Tanner, A Ruppert, SP Whitman, G … - springerlink.com
... on the following chromosome arms: 2p (n=2, hMSH2), 5q (n=9, APC), 7q (n=5, D5486,
c-met), 8q (n=8, Eto), 11q (n=6, MLL), 17q (n=6, BRCA1), 17p (n=3, TP53). ...
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Epigenetic and Chromatin Modifiers As Targeted Therapy of Hematologic Malignancies - Full text - MIT Libraries
KN Bhalla - J Clin Oncol, 2005 - jco.org
Search for: Limit by: All Topics ...
Cited by 2 - Web Search - dx.doi.org - jco.org - ncbi.nlm.nih.gov

Comprehensive genotypic analysis of leukemia: clinical and therapeutic implications
L Kelly, J Clark, DG Gilliland - Curr. Opin. Oncol, 2002 - co-oncology.com
... Published examples of progression in BCR/ABL positive CML include acquisition
of t(3;21) AML1/EVI1 or t(7;11) NUP98/HOXA9 gene rearrangements. ...
Cited by 11 - Web Search - siteman.wustl.edu - co-oncology.com - ncbi.nlm.nih.gov - Get it from MIT Libraries

G ENETICS OF M YELOID L EUKEMIAS - Full text - MIT Libraries
LM Kelly, DG Gilliland - Annual Review of Genomics and Human Genetics, 2002 - genom.annualreviews.org
Annual Reviews tagline graphic, ...
Cited by 35 - Web Search - 128.194.251.107 - fluid.annualreviews.org - ncbi.nlm.nih.gov - all 5 versions »

Pathogenesis of acute myeloid leukaemia and inv (16)(p 13; q 22): a paradigm for understanding … - Full text - MIT Libraries
JT Reilly - British Journal of Haematology, 2005 - blackwell-synergy.com
... A similar interference of AML1-dependent transcriptional activation has also been
reported for the AML1 ETO and AML1 EVI1 fusion proteins (Meyers et al, 1995 ...
Web Search - ingentaconnect.com - ncbi.nlm.nih.gov

Combined karyotyping, CGH and M-FISH analysis allows detailed characterization of unidentified … - Full text - MIT Libraries
M Van Gele, JH Leonard, N Van Roy, H Van Limbergen … - International Journal of Cancer, 2002 - doi.wiley.com
... 22q11.2/22q13), LSI SRY/CEP X (Yp11.3/Xp11.1-q11.1; Vysis, Downers Grove, IL), BAC
clones RPCI-11 178P16 (16q23-24), RPCI-11 1094H24 (17q21), EVI1 BAC clones ...
Cited by 13 - Web Search - ncbi.nlm.nih.gov

CLUB ESPANOL DE CITOLOGIA HEMATOLOGICA: REFLEXIONES EN EL DIAGNOSTICO DE LOS SINDROMES …
M Recio - db2.doyma.es
Page 1. CLUB ESPAÑOL DE CITOLOGÍA HEMATOLÓGICA: REFLEXIONES EN EL DIAGNÓSTICO
DE LOS SÍNDROMES MIELODISPLÁSICOS. VALORACIÓN DE LAS DISTINTAS ...
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Characterization of the recurrent translocation t (1; 1)(p 36. 3; q 21. 1-2) in non-Hodgkin lymphoma …
VS Lestou, O Ludkovski, JM Connors, RD Gascoyne, … - Genes Chromosomes and Cancer, 2003 - doi.wiley.com
... Establishment of a cell line with AML1-MTG8, TP53, and TP73 abnormalities from acute ...
MEL1, mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is ...
Cited by 7 - Web Search - ncbi.nlm.nih.gov - Get it from MIT Libraries

Professor Sakari Knuutila, Ph. D. Department of Medical Genetics Haartman Institute University of …
O Opponent - ethesis.helsinki.fi
... kinase erbB-4 precursor ERCC2 DNA excision repair protein EVI1 ecotropic viral ... TNFRSF10A
tumor necrosis factor receptor superfamily 10a TP53 tumor protein 53 ...
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The biology of CML blast crisis - Full text - MIT Libraries
C Cycle, S Transduction, G Expression - Blood, 2004 - bloodjournal.org
Institution: Google Indexer Sign In as Individual. Blood, 1 June 2004,
Vol. 103, No. 11, pp. 4010-4022. Prepublished online as a ...
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CLUB ESPANOL DE CITOLOGIA HEMATOLOGICA: EL LINFOBLASTO EN EL CONTEXTO
A DE LA LEUCEMIA LINFOBLASTICA - db2.doyma.es
Page 1. CLUB ESPAÑOL DE CITOLOGÍA HEMATOLÓGICA: EL LINFOBLASTO EN EL CONTEXTO DE
LA LEUCEMIA LINFOBLÁSTICA AGUDA C OORDINADORAS : M.ªC. J IMÉNEZ . ...
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Bibliography Current world literature
J Adami, O Nyren, R Bergstrom, A Ekbom, G Engholm, … - Current Opinion in Hematology, 1999 - co-hematology.com
July 1999, 6:4 > Bibliography Current world literature. < Previous | Next >.
ARTICLE LINKS: Permissions | View full size inline images. ...
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